William Tyor - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Microbiology Biology, Pathology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhang Z, Scanlan A, Koneru R, Morrell CR, Reece MD, Edwards E, Roa S, Gavegnano C, Bimonte-Nelson H, Arbiser J, Tyor W. Honokiol hexafluoro confers reversal of neuropathological markers of HIV infection in a murine SCID model. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. e00329. PMID 38388224 DOI: 10.1016/j.neurot.2024.e00329  0.594
2022 Scanlan A, Zhang Z, Koneru R, Reece M, Gavegnano C, Anderson AM, Tyor W. A Rationale and Approach to the Development of Specific Treatments for HIV Associated Neurocognitive Impairment. Microorganisms. 10. PMID 36422314 DOI: 10.3390/microorganisms10112244  0.564
2020 Gavegnano C, Haile W, Koneru R, Hurwitz SJ, Kohler JJ, Tyor WR, Schinazi RF. Novel method to quantify phenotypic markers of HIV-associated neurocognitive disorder in a murine SCID model. Journal of Neurovirology. PMID 32901392 DOI: 10.1007/s13365-020-00842-3  0.633
2020 Almodovar S, Wade BE, Porter KM, Smith JM, Lopez-Astacio RA, Bijli K, Kang BY, Cribbs SK, Guidot DM, Molehin D, McNair BK, Pumarejo-Gomez L, Perez Hernandez J, Salazar EA, Martinez EG, ... ... Tyor WR, et al. HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension. Scientific Reports. 10: 11696. PMID 32678115 DOI: 10.1038/S41598-020-68060-9  0.526
2019 Gavegnano C, Haile WB, Hurwitz S, Tao S, Jiang Y, Schinazi RF, Tyor WR. Baricitinib reverses HIV-associated neurocognitive disorders in a SCID mouse model and reservoir seeding in vitro. Journal of Neuroinflammation. 16: 182. PMID 31561750 DOI: 10.1186/S12974-019-1565-6  0.457
2019 Ozturk T, Kollhoff A, Anderson AM, Christina Howell J, Loring DW, Waldrop-Valverde D, Franklin D, Letendre S, Tyor WR, Hu WT. Linked CSF reduction of phosphorylated tau and IL-8 in HIV associated neurocognitive disorder. Scientific Reports. 9: 8733. PMID 31217522 DOI: 10.1038/S41598-019-45418-2  0.475
2019 Rosenthal J, Tyor W. Aging, comorbidities, and the importance of finding biomarkers for HIV-associated neurocognitive disorders. Journal of Neurovirology. PMID 30868422 DOI: 10.1007/S13365-019-00735-0  0.549
2018 Koneru R, Bimonte-Nelson H, Ciavatta V, Haile W, Elmore K, Ward J, Maroun L, Tyor WR. Reversing interferon-alpha neurotoxicity in a HIV-associated neurocognitive disorders mouse model. Aids (London, England). PMID 29683852 DOI: 10.1097/QAD.0000000000001836  0.5
2018 Anderson AM, Tyor WR, Mulligan MJ, Waldrop-Valverde D, Lennox JL, Letendre SL. HIV p24 antigen is quantifiable at low concentrations in human cerebrospinal fluid with digital ELISA and is associated with decreased neuropsychological performance. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 29385540 DOI: 10.1093/Cid/Ciy056  0.371
2017 Tyor WR, Bimonte-Nelson H. A mouse model of HIV-associated neurocognitive disorders: a brain-behavior approach to discover disease mechanisms and novel treatments. Journal of Neurovirology. PMID 28895064 DOI: 10.1007/s13365-017-0572-6  0.473
2016 Anderson AM, Lennox JL, Mulligan MM, Loring DW, Zetterberg H, Blennow K, Kessing C, Koneru R, Easley K, Tyor WR. Cerebrospinal fluid interferon alpha levels correlate with neurocognitive impairment in ambulatory HIV-Infected individuals. Journal of Neurovirology. PMID 27400930 DOI: 10.1007/s13365-016-0466-z  0.518
2016 Anderson AM, Lennox JL, Nguyen ML, Waldrop-Valverde D, Tyor WR, Loring DW. Preliminary study of a novel cognitive assessment device for the evaluation of HIV-associated neurocognitive impairment. Journal of Neurovirology. PMID 27245594 DOI: 10.1007/s13365-016-0458-z  0.496
2016 Anderson AM, Schinazi RF, Tyor WR. HIV latency reversal research and the potential effects on the central nervous system: is concern warranted? Journal of the International Aids Society. 19: 21008. PMID 27166355  0.472
2016 Haile WB, Gavegnano C, Tao S, Jiang Y, Schinazi RF, Tyor WR. The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model. Neurobiology of Disease. PMID 26851503 DOI: 10.1016/J.Nbd.2016.02.007  0.591
2016 Anderson AM, Schinazi RF, Tyor WR. HIV latency reversal research and the potential effects on the central nervous system: Is concern warranted? Journal of the International Aids Society. 19. DOI: 10.7448/IAS.19.1.21008  0.472
2016 Cook J, Tyor W. The Pathogenesis of HIV-Associated Dementia: Recent Advances Using a SCID Mouse Model of HIV-Encephalitis Einstein Journal of Biology and Medicine. 22: 32. DOI: 10.23861/Ejbm2006229  0.624
2015 Rumbaugh JA, Tyor W. HIV-associated neurocognitive disorders: Five new things. Neurology. Clinical Practice. 5: 224-231. PMID 26124979 DOI: 10.1212/CPJ.0000000000000117  0.546
2015 Kessing CF, Tyor WR. Interferon-α induces neurotoxicity through activation of the type I receptor and the GluN2A subunit of the NMDA receptor. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 35: 317-24. PMID 25517826 DOI: 10.1089/jir.2014.0105  0.339
2014 Fritz-French C, Shawahna R, Ward JE, Maroun LE, Tyor WR. The recombinant vaccinia virus gene product, B18R, neutralizes interferon alpha and alleviates histopathological complications in an HIV encephalitis mouse model. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 34: 510-7. PMID 24564363 DOI: 10.1089/jir.2013.0072  0.367
2014 Koneru R, Olive MF, Tyor WR. Combined antiretroviral therapy reduces brain viral load and pathological features of HIV encephalitis in a mouse model. Journal of Neurovirology. 20: 9-17. PMID 24415129 DOI: 10.1007/S13365-013-0223-5  0.579
2013 Tyor W, Fritz-French C, Nath A. Effect of HIV clade differences on the onset and severity of HIV-associated neurocognitive disorders. Journal of Neurovirology. 19: 515-22. PMID 24129908 DOI: 10.1007/S13365-013-0206-6  0.613
2013 Rao VR, Neogi U, Talboom JS, Padilla L, Rahman M, Fritz-French C, Gonzalez-Ramirez S, Verma A, Wood C, Ruprecht RM, Ranga U, Azim T, Joska J, Eugenin E, Shet A, ... ... Tyor WR, et al. Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence. Retrovirology. 10: 61. PMID 23758766 DOI: 10.1186/1742-4690-10-61  0.565
2013 Rumbaugh J, Harrison T, Tyor W. Human immunodeficiency virus infection/AIDS Birkhauser Advances in Infectious Diseases. 145-181. DOI: 10.1007/978-3-0348-0425-7_7  0.564
2012 Tyor WR, Hwang HY, Fritz-French C. Morphine exposure during HIV encephalitis in SCID mice. Neurochemical Research. 37: 2836-41. PMID 22965853 DOI: 10.1007/s11064-012-0877-z  0.441
2012 Fritz-French C, Tyor W. Interferon-α (IFNα) neurotoxicity. Cytokine & Growth Factor Reviews. 23: 7-14. PMID 22342642 DOI: 10.1016/J.Cytogfr.2012.01.001  0.49
2009 Sas AR, Bimonte-Nelson H, Smothers CT, Woodward J, Tyor WR. Interferon-alpha causes neuronal dysfunction in encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3948-55. PMID 19321791 DOI: 10.1523/Jneurosci.5595-08.2009  0.671
2008 Rao VR, Sas AR, Eugenin EA, Siddappa NB, Bimonte-Nelson H, Berman JW, Ranga U, Tyor WR, Prasad VR. HIV-1 clade-specific differences in the induction of neuropathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10010-6. PMID 18829958 DOI: 10.1523/Jneurosci.2955-08.2008  0.673
2008 Sas A, Jones R, Tyor W. Intra-peritoneal injection of polyclonal anti-interferon alpha antibodies cross the blood brain barrier and neutralize interferon alpha Neurochemical Research. 33: 2281-2287. PMID 18461447 DOI: 10.1007/S11064-008-9715-8  0.381
2008 Sas AR, Bimonte-Nelson HA, Tyor WR. Cognitive dysfunction in HIV encephalitic SCID mice correlates with levels of Interferon-α in the brain (AIDS (2007) 21, 16, (2151-2159)) Aids. 22: 555.  0.517
2007 Sas AR, Bimonte-Nelson HA, Tyor WR. Cognitive dysfunction in HIV encephalitic SCID mice correlates with levels of Interferon-alpha in the brain. Aids (London, England). 21: 2151-9. PMID 18090041 DOI: 10.1097/Qad.0B013E3282F08C2F  0.677
2007 Cook-Easterwood J, Middaugh LD, Griffin WC, Khan I, Tyor WR. Highly active antiretroviral therapy of cognitive dysfunction and neuronal abnormalities in SCID mice with HIV encephalitis. Experimental Neurology. 205: 506-12. PMID 17442303 DOI: 10.1016/J.Expneurol.2007.03.007  0.582
2007 Griffin WC, Middaugh LD, Tyor WR. Chronic cocaine exposure in the SCID mouse model of HIV encephalitis. Brain Research. 1134: 214-9. PMID 17189621 DOI: 10.1016/J.Brainres.2006.11.059  0.455
2006 Hauser KF, El-Hage N, Buch S, Nath A, Tyor WR, Bruce-Keller AJ, Knapp PE. Impact of opiate-HIV-1 interactions on neurotoxic signaling. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 98-105. PMID 18040795 DOI: 10.1007/S11481-005-9000-4  0.501
2005 Hauser KF, El-Hage N, Buch S, Berger JR, Tyor WR, Nath A, Bruce-Keller AJ, Knapp PE. Molecular targets of opiate drug abuse in neuroAIDS. Neurotoxicity Research. 8: 63-80. PMID 16260386 DOI: 10.1007/Bf03033820  0.37
2005 Cook JE, Dasgupta S, Middaugh LD, Terry EC, Gorry PR, Wesselingh SL, Tyor WR. Highly active antiretroviral therapy and human immunodeficiency virus encephalitis. Annals of Neurology. 57: 795-803. PMID 15852478 DOI: 10.1002/Ana.20479  0.572
2004 Griffin WC, Middaugh LD, Cook JE, Tyor WR. The severe combined immunodeficient (SCID) mouse model of human immunodeficiency virus encephalitis: deficits in cognitive function. Journal of Neurovirology. 10: 109-15. PMID 15204929 DOI: 10.1080/13550280490428333  0.602
1998 Avgeropoulos NG, Burris GW, Ohlandt GW, Wesselingh SL, Markham RB, Tyor WR. Potential relationships between the presence of HIV, macrophages, and astrogliosis in SCID mice with HIV encephalitis. Journal of Neuro-Aids. 2: 1-20. PMID 16873182 DOI: 10.1300/J128v02n01_01  0.594
1998 Avgeropoulos N, Kelley B, Middaugh L, Arrigo S, Persidsky Y, Gendelman HE, Tyor WR. SCID mice with HIV encephalitis develop behavioral abnormalities. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 18: 13-20. PMID 9593453 DOI: 10.1097/00042560-199805010-00003  0.635
1997 Griffin D, Levine B, Tyor W, Ubol S, Desprès P. The role of antibody in recovery from alphavirus encephalitis Immunological Reviews. 159: 155-161. PMID 9416509 DOI: 10.1111/J.1600-065X.1997.Tb01013.X  0.41
1997 da Cunha A, Jefferson JJ, Tyor WR, Glass JD, Jannotta FS, Cottrell JR, Resau JH. Transforming growth factor-beta1 in adult human microglia and its stimulated production by interleukin-1. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 17: 655-64. PMID 9402103  0.411
1996 Persidsky Y, Limoges J, McComb R, Bock P, Baldwin T, Tyor W, Patil A, Nottet HS, Epstein L, Gelbard H, Flanagan E, Reinhard J, Pirruccello SJ, Gendelman HE. Human immunodeficiency virus encephalitis in SCID mice. The American Journal of Pathology. 149: 1027-53. PMID 8780406  0.604
1996 Avgeropouios N, Burris G, Qhlandt G, Wesselingh S, Gendelman H, Markham R, Tyor W. The presence of HIV in SCID MICE with HIV encephalitis correlates with gliosis Faseb Journal. 10.  0.594
1995 Rho MB, Wesselingh S, Glass JD, McArthur JC, Choi S, Griffin J, Tyor WR. A potential role for interferon-alpha in the pathogenesis of HIV-associated dementia. Brain, Behavior, and Immunity. 9: 366-77. PMID 8903853 DOI: 10.1006/Brbi.1995.1034  0.444
1995 Tyor WR, Wesselingh SL, Griffin JW, McArthur JC, Griffin DE. Unifying hypothesis for the pathogenesis of HIV-associated dementia complex, vacuolar myelopathy, and sensory neuropathy Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 9: 379-388. PMID 7600105  0.567
1995 Tyor WR, Wesselingh SL, Griffin JW, McArthur JC, Griffin DE. Unifying Hypothesis for the Pathogenesis of HIV-Associated Dementia Complex, Vacuolar Myelopathy, and Sensory Neuropathy Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 9: 379???388. DOI: 10.1097/00042560-199508000-00008  0.471
1995 Avgeropoulos N, Burris G, Ohlandt G, Wesselingh S, Gendelman H, Tyor W. Mononuclear Phagocytes and Astrocytes Participate in the Pathogenesis of HIV Encephalitis Journal of Neuroimmunology. 63: 99. DOI: 10.1016/0165-5728(96)80984-2  0.515
1994 Fuchs D, Murr C, Reibnegger G, Wachler H, Tyor WR, Griffin DE. HIV myelopathy [3] Neurology. 44: 578-579. PMID 8145942  0.533
1994 Griffin DE, Levine B, Tyor WR, Tucker PC, Hardwick JM. Age-dependent susceptibility to fatal encephalitis: alphavirus infection of neurons. Archives of Virology. Supplementum. 9: 31-9. PMID 8032263 DOI: 10.1007/978-3-7091-9326-6_4  0.311
1994 Tyor WR, Griffin DE. HIV myelopathy-RRR Neurology. 44: 578-578. DOI: 10.1212/Wnl.44.3_Part_1.578-C  0.533
1994 Tyor WR, Griffin DE. Re: HIV myelopathy Neurology. 44: 578-579.  0.533
1993 Wesselingh SL, Power C, Glass JD, Tyor WR, McArthur JC, Farber JM, Griffin JW, Griffin DE. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Annals of Neurology. 33: 576-82. PMID 8498837 DOI: 10.1002/Ana.410330604  0.438
1993 Tyor WR, Glass JD, Baumrind N, McArthur JC, Griffin JW, Becker PS, Griffin DE. Cytokine expression of macrophages in HIV-1-associated vacuolar myelopathy. Neurology. 43: 1002-9. PMID 8492917 DOI: 10.1212/Wnl.43.5.1002  0.459
1993 Tyor WR, Power C, Gendelman HE, Markham RB. A model of human immunodeficiency virus encephalitis in scid mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 8658-62. PMID 8378344 DOI: 10.1073/Pnas.90.18.8658  0.627
1992 Tyor WR, Glass JD, Griffin JW, Becker PS, McArthur JC, Bezman L, Griffin DE. Cytokine expression in the brain during the acquired immunodeficiency syndrome. Annals of Neurology. 31: 349-60. PMID 1586135 DOI: 10.1002/Ana.410310402  0.518
1992 Griffin JW, Tyor W, Glass J, Wesselingh S, Griffin D, McArthur JC. Peripheral neuropathy in HIV infection: Lessons for the CNS Journal of the Neurological Sciences. 113: 129. DOI: 10.1016/0022-510X(92)90232-A  0.61
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