Haruko Miyazaki, Ph.D. - Related publications

Laboratory for Structural Neuropathology RIKEN Brain Science Institute, Wakō-shi, Saitama-ken, Japan 
polyglutamine disorders
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Stendel C, D'Adamo MC, Wiessner M, Dusl M, Cenciarini M, Belia S, Nematian-Ardestani E, Bauer P, Senderek J, Klopstock T, Pessia M. Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia. International Journal of Molecular Sciences. 21. PMID 32471306 DOI: 10.3390/ijms21113810   
2020 Bekdash R, Klein AD, Yazawa M. Timothy syndrome iPSC modeling. Molecular and Cellular Neurosciences. 107: 103529. PMID 32629111 DOI: 10.1016/j.mcn.2020.103529   
2020 Thapak P, Vaidya B, Joshi HC, Singh JN, Sharma SS. Therapeutic Potential of Pharmacological Agents Targeting TRP Channels in CNS Disorders. Pharmacological Research. 105026. PMID 32562815 DOI: 10.1016/j.phrs.2020.105026   
2020 Peters CH, Myers ME, Juchno J, Haimbaugh C, Bichraoui H, Du Y, Bankston JR, Walker LA, Proenza C. Isoform-specific regulation of HCN4 channels by a family of endoplasmic reticulum proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 32647060 DOI: 10.1073/pnas.2006238117   
2020 Li J, Maghera J, Lamothe SM, Marco EJ, Kurata HT. Heteromeric assembly of truncated neuronal Kv7 channels: implications for neurological disease and pharmacotherapy. Molecular Pharmacology. PMID 32580997 DOI: 10.1124/mol.120.119644   
2020 Wadsworth PA, Singh AK, Nguyen N, Dvorak NM, Tapia CM, Russell WK, Stephan C, Laezza F. JAK2 regulates Nav1.6 channel function via FGF14 phosphorylation. Biochimica Et Biophysica Acta. Molecular Cell Research. 118786. PMID 32599005 DOI: 10.1016/j.bbamcr.2020.118786   
2020 Saegusa H, Li X, Wang X, Kayakiri M, Tanabe T. Knockdown of microglial Cav2.2 N-type voltage-dependent Ca channel ameliorates behavioral deficits in a mouse model of Parkinson's disease. Febs Letters. PMID 32484574 DOI: 10.1002/1873-3468.13853   
2020 Lin W, Qin J, Ni G, Li Y, Xie H, Yu J, Li H, Sui L, Guo Q, Fang Z, Zhou L. Downregulation of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) in the hippocampus of patients with medial temporal lobe epilepsy and hippocampal sclerosis (MTLE-HS). Hippocampus. PMID 32543742 DOI: 10.1002/hipo.23219   
2020 Handklo-Jamal R, Meisel E, Yakubovich D, Vysochek L, Beinart R, Glikson M, McMullen JR, Dascal N, Nof E, Oz S. Andersen-Tawil Syndrome Is Associated With Impaired PIP Regulation of the Potassium Channel Kir2.1. Frontiers in Pharmacology. 11: 672. PMID 32499698 DOI: 10.3389/fphar.2020.00672   
2020 Zybura AS, Baucum AJ, Rush AM, Cummins TR, Hudmon A. CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability. The Journal of Biological Chemistry. PMID 32611770 DOI: 10.1074/jbc.RA120.014062   
2020 Chen ZC, Wang TT, Bian W, Ye X, Li MY, Du JJ, Zhou P, Cui HR, Ding YQ, Ren YH, Qi SS, Yuan YY, Liao M, Sun CY. Allopregnanolone restores the tyrosine hydroxylase-positive neurons and motor performance in a 6-OHDA-injected mouse model. Cns Neuroscience & Therapeutics. PMID 32602622 DOI: 10.1111/cns.13432   
2020 Vickstrom CR, Liu X, Zhang Y, Mu L, Kelly TJ, Yan X, Hu MM, Snarrenberg ST, Liu QS. T-type calcium channels contribute to burst firing in a subpopulation of medial habenula neurons. Eneuro. PMID 32719103 DOI: 10.1523/ENEURO.0201-20.2020   
2020 Ortner NJ, Kaserer T, Copeland JN, Striessnig J. De novo CACAN1D Ca channelopathies: clinical phenotypes and molecular mechanism. Pflugers Archiv : European Journal of Physiology. PMID 32583268 DOI: 10.1007/s00424-020-02418-w   
2020 Salvage SC, Huang CL, Jackson AP. Cell-Adhesion Properties of β-Subunits in the Regulation of Cardiomyocyte Sodium Channels. Biomolecules. 10. PMID 32630316 DOI: 10.3390/biom10070989   
2020 Zhao Y, Ung PM, Zahoránszky-Kőhalmi G, Zakharov AV, Martinez NJ, Simeonov A, Glaaser IW, Rai G, Schlessinger A, Marugan JJ, Slesinger PA. Identification of a G-Protein-Independent Activator of GIRK Channels. Cell Reports. 31: 107770. PMID 32553165 DOI: 10.1016/j.celrep.2020.107770   
2020 Burton MJ, Cresser-Brown J, Thomas M, Portolano N, Basran J, Freeman SL, Kwon H, Bottrill AR, Llansola-Portoles MJ, Pascal AA, Jukes-Jones R, Chernova T, Schmid R, Davies NW, Storey NM, et al. Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel. The Journal of Biological Chemistry. PMID 32723862 DOI: 10.1074/jbc.RA120.014150   
2020 Liu N, Yan F, Ma Q, Zhao J. Modulation of TRPV4 and BKCa for treatment of brain diseases. Bioorganic & Medicinal Chemistry. 28: 115609. PMID 32690264 DOI: 10.1016/j.bmc.2020.115609   
2020 van der Horst J, Greenwood IA, Jepps TA. Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels. Frontiers in Physiology. 11: 727. PMID 32695022 DOI: 10.3389/fphys.2020.00727   
2020 Thompson E, Eldstrom J, Fedida D. Hormonal Signaling Actions on Kv7.1 (KCNQ1) Channels. Annual Review of Pharmacology and Toxicology. PMID 32667860 DOI: 10.1146/annurev-pharmtox-010919-023645   
2020 Nguyen HM, di Lucente J, Chen YJ, Cui Y, Ibrahim RH, Pennington MW, Jin LW, Maezawa I, Wulff H. Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microglia. Glia. PMID 32525239 DOI: 10.1002/glia.23847   
2020 Akter N, Fukaya R, Adachi R, Kawabe H, Kuba H. Structural and functional refinement of the axon initial segment in avian cochlear nucleus during development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32719016 DOI: 10.1523/JNEUROSCI.3068-19.2020   
2020 Ruan Z, Orozco IJ, Du J, Lü W. Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature. PMID 32494015 DOI: 10.1038/s41586-020-2357-y   
2020 Peters CH, Watkins AR, Poirier OL, Ruben PC. E1784K, the most common Brugada syndrome and long-QT syndrome type 3 mutant, disrupts sodium channel inactivation through two separate mechanisms. The Journal of General Physiology. 152. PMID 32569350 DOI: 10.1085/jgp.202012595   
2020 O'Connor B, Robbins N, Koch SE, Rubinstein J. TRPV2 channel-based therapies in the cardiovascular field. Molecular underpinnings of clinically relevant therapies. Progress in Biophysics and Molecular Biology. PMID 32565182 DOI: 10.1016/j.pbiomolbio.2020.06.001   
2020 Pai VP, Cervera J, Mafe S, Willocq V, Lederer EK, Levin M. HCN2 Channel-Induced Rescue of Brain Teratogenesis Local and Long-Range Bioelectric Repair. Frontiers in Cellular Neuroscience. 14: 136. PMID 32528251 DOI: 10.3389/fncel.2020.00136   
2020 McCauley MD, Hong L, Sridhar A, Menon A, Perike S, Zhang M, da Silva IB, Yan J, Bonini MG, Ai X, Rehman J, Darbar D. Ion Channel and Structural Remodeling in Obesity: Mediated Atrial Fibrillation. Circulation. Arrhythmia and Electrophysiology. PMID 32654503 DOI: 10.1161/CIRCEP.120.008296   
2020 Chen C, Liu L, Shu YQ, Jing P, Lu Y, Zhang XX, Zong XG, Guo LJ, Li CJ. Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons. Neuroscience Bulletin. PMID 32519067 DOI: 10.1007/s12264-020-00513-7   
2020 Shin DH, Kim M, Kim Y, Jun I, Jung J, Nam JH, Cheng MH, Lee MG. Bicarbonate permeation through anion channels: its role in health and disease. Pflugers Archiv : European Journal of Physiology. PMID 32621085 DOI: 10.1007/s00424-020-02425-x   
2020 Mohammed F, Rashid-Doubell F, Taha S, Cassidy S, Fredericks S. Effects of curcumin complexes on MDA‑MB‑231 breast cancer cell proliferation. International Journal of Oncology. 57: 445-455. PMID 32626932 DOI: 10.3892/ijo.2020.5065   
2020 Cheung TP, Choe JY, Richmond JE, Kim H. BK channel density is regulated by endoplasmic reticulum associated degradation and influenced by the SKN-1A/NRF1 transcription factor. Plos Genetics. 16: e1008829. PMID 32502151 DOI: 10.1371/journal.pgen.1008829   
2020 Parrell D, Kroos L. Channels modestly impact compartment-specific ATP levels during Bacillus subtilis sporulation and a rise in the mother cell ATP level is not necessary for Pro-σ cleavage. Molecular Microbiology. PMID 32515031 DOI: 10.1111/mmi.14560   
2020 Schoepf CL, Zeidler M, Spiecker L, Kern G, Lechner J, Kummer KK, Kress M. Selected Ionotropic Receptors and Voltage-Gated Ion Channels: More Functional Competence for Human Induced Pluripotent Stem Cell (iPSC)-Derived Nociceptors. Brain Sciences. 10. PMID 32503260 DOI: 10.3390/brainsci10060344   
2020 Liu S, Pan X, Cheng W, Deng B, He Y, Zhang L, Ning Y, Li J. Tubeimoside I Antagonizes Yoda1-Evoked Piezo1 Channel Activation. Frontiers in Pharmacology. 11: 768. PMID 32523536 DOI: 10.3389/fphar.2020.00768   
2020 Hasan S, Megaro A, Cenciarini M, Coretti L, Botti FM, Imbrici P, Steinbusch HWM, Hunter T, Hunter G, Pessia M, D'Adamo MC. Electromechanical coupling of the Kv1.1 voltage-gated K channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker. Pflugers Archiv : European Journal of Physiology. PMID 32577860 DOI: 10.1007/s00424-020-02414-0   
2020 Zou X, Conrad LJ, Koschinski K, Schlichthörl G, Preisig-Müller R, Netz E, Krüger J, Daut J, Renigunta V. The phosphodiesterase inhibitor IBMX blocks the potassium channel THIK-1 from the extracellular side. Molecular Pharmacology. PMID 32467103 DOI: 10.1124/molpharm.120.000011   
2020 Kwon Y, Haam CE, Byeon S, Choi SJ, Shin DH, Choi SK, Lee YH. Vasodilatory Effect of Extract in Rat Mesenteric Arteries. Molecules (Basel, Switzerland). 25. PMID 32664327 DOI: 10.3390/molecules25143160   
2020 Shen XM, Di L, Shen S, Zhao Y, Neumeyer AM, Selcen D, Sine SM, Engel AG. A novel fast-channel myasthenia caused by mutation in β subunit of AChR reveals subunit-specific contribution of the intracellular M1-M2 linker to channel gating. Experimental Neurology. 113375. PMID 32504635 DOI: 10.1016/j.expneurol.2020.113375   
2020 Fiore M, Picco C, Moran O. Correctors modify the bicarbonate permeability of F508del-CFTR. Scientific Reports. 10: 8440. PMID 32439937 DOI: 10.1038/s41598-020-65287-4   
2020 Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Ngan Pham NY, Molnar G, Streicher JM, Patek M, et al. A modulator of the low-voltage activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies. Pain. PMID 32541387 DOI: 10.1097/j.pain.0000000000001955   
2020 Liu N, Wu J, Chen Y, Zhao J. Channels that Cooperate with TRPV4 in the Brain. Journal of Molecular Neuroscience : Mn. PMID 32524421 DOI: 10.1007/s12031-020-01574-z   
2020 Zou X, Conrad LJ, Koschinsky K, Schlichthörl G, Preisig-Müller R, Netz E, Krüger J, Daut J, Renigunta V. The Phosphodiesterase Inhibitor IBMX Blocks the Potassium Channel THIK-1 from the Extracellular Side. Molecular Pharmacology. 98: 143-155. PMID 32616523 DOI: 10.1124/mol.120.000011   
2020 Wie J, Bharthur A, Wolfgang M, Narayanan V, Ramsey K, , Aranda K, Zhang Q, Zhou Y, Ren D. Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex. Nature Communications. 11: 3351. PMID 32620897 DOI: 10.1038/s41467-020-17105-8   
2020 Maldonado O, Jenkins A, Belalcazar HM, Hernandez-Cuervo H, Hyman KM, Ladaga G, Padilla L, de Erausquin GA. Age-dependent neuroprotective effect of an SK3 channel agonist on excitotoxity to dopaminergic neurons in organotypic culture. Plos One. 15: e0223633. PMID 32701951 DOI: 10.1371/journal.pone.0223633   
2020 Takahashi N, Tsuzuno T, Mineo S, Yamada-Hara M, Aoki-Nonaka Y, Tabeta K. Epithelial TRPV1 channels: Expression, function, and pathogenicity in the oral cavity. Journal of Oral Biosciences. PMID 32544616 DOI: 10.1016/j.job.2020.05.005   
2020 Rennie KJ, Meredith FL. Persistent and resurgent Na currents in vestibular calyx afferents. Journal of Neurophysiology. PMID 32667253 DOI: 10.1152/jn.00124.2020   
2020 Neumaier F, Alpdogan S, Hescheler J, Schneider T. Zn2+-induced changes in Cav2.3 channel function: An electrophysiological and modeling study. The Journal of General Physiology. 152. PMID 32559275 DOI: 10.1085/jgp.202012585   
2020 Salzer JL. Control of Channel Clustering by Cleavage. Neuron. 106: 707-709. PMID 32497505 DOI: 10.1016/j.neuron.2020.05.017   
2020 Gigolaev AM, Kuzmenkov AI, Peigneur S, Tabakmakher VM, Pinheiro-Junior EL, Chugunov AO, Efremov RG, Tytgat J, Vassilevski AA. Tuning Scorpion Toxin Selectivity: Switching From K1.1 to K1.3. Frontiers in Pharmacology. 11: 1010. PMID 32733247 DOI: 10.3389/fphar.2020.01010   
2020 Lin M, Colon-Perez LM, Sambo DO, Miller DR, Lebowitz JJ, Jimenez-Rondan F, Cousins RJ, Horenstein N, Aydemir TB, Febo M, Khoshbouei H. Mechanism of manganese dysregulation of dopamine neuronal activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32576620 DOI: 10.1523/JNEUROSCI.2830-19.2020   
2020 Kasap M, Dwyer DS. Clozapine, nimodipine and endosulfan differentially suppress behavioral defects caused by gain-of-function mutations in a two-pore domain K channel (UNC-58). Neuroscience Research. PMID 32681854 DOI: 10.1016/j.neures.2020.07.006