| Year |
Citation |
Score |
| 2021 |
Rodden LN, Chutake YK, Gilliam K, Lam C, Soragni E, Hauser L, Gilliam M, Wiley G, Anderson MP, Gottesfeld JM, Lynch DR, Bidichandani SI. Methylated and unmethylated epialleles support variegated epigenetic silencing in Friedreich ataxia. Human Molecular Genetics. PMID 33432325 DOI: 10.1093/hmg/ddaa267 |
0.308 |
|
| 2019 |
Gottesfeld JM. Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31317428 DOI: 10.1007/S13311-019-00764-X |
0.395 |
|
| 2019 |
Gottesfeld JM. Milestones in transcription and chromatin published in the . The Journal of Biological Chemistry. 294: 1652-1660. PMID 30710013 DOI: 10.1074/Jbc.Tm118.004162 |
0.429 |
|
| 2018 |
Lai JI, Nachun D, Petrosyan L, Throesch B, Campau E, Gao F, Baldwin KK, Coppola G, Gottesfeld JM, Soragni E. Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures. The Journal of Biological Chemistry. PMID 30552117 DOI: 10.1074/Jbc.Ra118.006515 |
0.716 |
|
| 2018 |
Gottesfeld JM, Carey MF. Introduction to Thematic Minireview Series: Chromatin and Transcription. The Journal of Biological Chemistry. PMID 30068547 DOI: 10.1074/Jbc.Tm118.004544 |
0.427 |
|
| 2018 |
Soragni E, Petrosyan L, Rinkoski TA, Wieben ED, Baratz KH, Fautsch MP, Gottesfeld JM. Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy. Investigative Ophthalmology & Visual Science. 59: 1888-1896. PMID 29677349 DOI: 10.1167/Iovs.17-23265 |
0.34 |
|
| 2017 |
Lai JI, Leman LJ, Ku S, Vickers CJ, Olsen CA, Montero A, Ghadiri MR, Gottesfeld JM. Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells. Bioorganic & Medicinal Chemistry Letters. PMID 28648462 DOI: 10.1016/J.Bmcl.2017.06.027 |
0.765 |
|
| 2016 |
Soragni E, Gottesfeld JM. Translating HDAC inhibitors in Friedrich's ataxia. Expert Opinion On Orphan Drugs. 4: 961-970. PMID 28392990 DOI: 10.1080/21678707.2016.1215910 |
0.399 |
|
| 2016 |
Jia H, Wang Y, Morris CD, Jacques V, Gottesfeld JM, Rusche JR, Thomas EA. The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice. Plos One. 11: e0152498. PMID 27031333 DOI: 10.1371/Journal.Pone.0152498 |
0.362 |
|
| 2016 |
Soragni E, Gottesfeld JM. Translating HDAC inhibitors in Friedreich’s ataxia Expert Opinion On Orphan Drugs. 4: 961-970. DOI: 10.1080/21678707.2016.1215910 |
0.301 |
|
| 2015 |
Soragni E, Chou CJ, Rusche JR, Gottesfeld JM. Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia. Frontiers in Neurology. 6: 44. PMID 25798128 DOI: 10.3389/Fneur.2015.00044 |
0.413 |
|
| 2015 |
Du J, Aleff RA, Soragni E, Kalari K, Nie J, Tang X, Davila J, Kocher JP, Patel SV, Gottesfeld JM, Baratz KH, Wieben ED. RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy. The Journal of Biological Chemistry. 290: 5979-90. PMID 25593321 DOI: 10.1074/Jbc.M114.621607 |
0.331 |
|
| 2014 |
Soragni E, Miao W, Iudicello M, Jacoby D, De Mercanti S, Clerico M, Longo F, Piga A, Ku S, Campau E, Du J, Penalver P, Rai M, Madara JC, Nazor K, ... ... Gottesfeld JM, et al. Epigenetic therapy for Friedreich ataxia. Annals of Neurology. 76: 489-508. PMID 25159818 DOI: 10.1002/Ana.24260 |
0.764 |
|
| 2014 |
Shan B, Xu C, Zhang Y, Xu T, Gottesfeld JM, Yates JR. Quantitative proteomic analysis identifies targets and pathways of a 2-aminobenzamide HDAC inhibitor in Friedreich's ataxia patient iPSC-derived neural stem cells. Journal of Proteome Research. 13: 4558-66. PMID 24933366 DOI: 10.1021/Pr500514R |
0.363 |
|
| 2014 |
Rao M, Gottesfeld JM. Introduction to thematic minireview series: Development of human therapeutics based on induced pluripotent stem Cell (iPSC) technology Journal of Biological Chemistry. 289: 4553-4554. PMID 24362035 DOI: 10.1074/Jbc.R113.543652 |
0.313 |
|
| 2013 |
Du J, Campau E, Soragni E, Jespersen C, Gottesfeld JM. Length-dependent CTG·CAG triplet-repeat expansion in myotonic dystrophy patient-derived induced pluripotent stem cells. Human Molecular Genetics. 22: 5276-87. PMID 23933738 DOI: 10.1093/Hmg/Ddt386 |
0.377 |
|
| 2013 |
Gottesfeld JM, Rusche JR, Pandolfo M. Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia. Journal of Neurochemistry. 126: 147-54. PMID 23859350 DOI: 10.1111/Jnc.12302 |
0.476 |
|
| 2012 |
Denu JM, Gottesfeld JM. Minireview series on sirtuins: from biochemistry to health and disease. The Journal of Biological Chemistry. 287: 42417-8. PMID 23086946 DOI: 10.1074/Jbc.R112.428862 |
0.321 |
|
| 2012 |
Du J, Campau E, Soragni E, Ku S, Puckett JW, Dervan PB, Gottesfeld JM. Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells. The Journal of Biological Chemistry. 287: 29861-72. PMID 22798143 DOI: 10.1074/Jbc.M112.391961 |
0.787 |
|
| 2012 |
Soragni E, Xu C, Plasterer HL, Jacques V, Rusche JR, Gottesfeld JM. Rationale for the development of 2-aminobenzamide histone deacetylase inhibitors as therapeutics for Friedreich ataxia. Journal of Child Neurology. 27: 1164-73. PMID 22764181 DOI: 10.1177/0883073812448533 |
0.362 |
|
| 2012 |
Jespersen C, Soragni E, James Chou C, Arora PS, Dervan PB, Gottesfeld JM. Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells. Bioorganic & Medicinal Chemistry Letters. 22: 4068-71. PMID 22607671 DOI: 10.1016/J.Bmcl.2012.04.090 |
0.666 |
|
| 2012 |
Jia H, Pallos J, Jacques V, Lau A, Tang B, Cooper A, Syed A, Purcell J, Chen Y, Sharma S, Sangrey GR, Darnell SB, Plasterer H, Sadri-Vakili G, Gottesfeld JM, et al. Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease. Neurobiology of Disease. 46: 351-61. PMID 22590724 DOI: 10.1016/J.Nbd.2012.01.016 |
0.373 |
|
| 2012 |
Polak U, Hirsch C, Ku S, Gottesfeld J, Dent SY, Napierala M. Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts. Journal of Visualized Experiments : Jove. PMID 22370855 DOI: 10.3791/3416 |
0.764 |
|
| 2012 |
Soragni E, Ku S, Gottesfeld JM. Epigenetics: Analysis of Histone Post-Translational Modifications by Chromatin Immunoprecipitation Human Stem Cell Manual. 313-323. DOI: 10.1016/B978-0-12-385473-5.00019-9 |
0.781 |
|
| 2011 |
Xu C, Soragni E, Jacques V, Rusche JR, Gottesfeld JM. Improved Histone Deacetylase Inhibitors as Therapeutics for the Neurodegenerative Disease Friedreich's Ataxia: A New Synthetic Route. Pharmaceuticals (Basel, Switzerland). 4: 1578-1590. PMID 27721337 DOI: 10.3390/Ph4121578 |
0.356 |
|
| 2011 |
Coppola G, Burnett R, Perlman S, Versano R, Gao F, Plasterer H, Rai M, Saccá F, Filla A, Lynch DR, Rusche JR, Gottesfeld JM, Pandolfo M, Geschwind DH. A gene expression phenotype in lymphocytes from Friedreich ataxia patients. Annals of Neurology. 70: 790-804. PMID 22162061 DOI: 10.1002/Ana.22526 |
0.71 |
|
| 2011 |
Soragni E, Xu C, Cooper A, Plasterer HL, Rusche JR, Gottesfeld JM. Evaluation of histone deacetylase inhibitors as therapeutics for neurodegenerative diseases. Methods in Molecular Biology (Clifton, N.J.). 793: 495-508. PMID 21913121 DOI: 10.1007/978-1-61779-328-8_32 |
0.378 |
|
| 2011 |
Gottesfeld JM. Introduction to the thematic minireview series on epigenetics. The Journal of Biological Chemistry. 286: 18345-6. PMID 21454488 DOI: 10.1074/Jbc.R111.243527 |
0.452 |
|
| 2011 |
Sandi C, Pinto RM, Al-Mahdawi S, Ezzatizadeh V, Barnes G, Jones S, Rusche JR, Gottesfeld JM, Pook MA. Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model. Neurobiology of Disease. 42: 496-505. PMID 21397024 DOI: 10.1016/J.Nbd.2011.02.016 |
0.379 |
|
| 2011 |
Laurent LC, Ulitsky I, Slavin I, Tran H, Schork A, Morey R, Lynch C, Harness JV, Lee S, Barrero MJ, Ku S, Martynova M, Semechkin R, Galat V, Gottesfeld J, et al. Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. Cell Stem Cell. 8: 106-18. PMID 21211785 DOI: 10.1016/J.Stem.2010.12.003 |
0.77 |
|
| 2010 |
Ku S, Soragni E, Campau E, Thomas EA, Altun G, Laurent LC, Loring JF, Napierala M, Gottesfeld JM. Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability. Cell Stem Cell. 7: 631-7. PMID 21040903 DOI: 10.1016/J.Stem.2010.09.014 |
0.806 |
|
| 2010 |
Rai M, Soragni E, Chou CJ, Barnes G, Jones S, Rusche JR, Gottesfeld JM, Pandolfo M. Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model. Plos One. 5: e8825. PMID 20098685 DOI: 10.1371/Journal.Pone.0008825 |
0.409 |
|
| 2010 |
Hutt DM, Herman D, Rodrigues AP, Noel S, Pilewski JM, Matteson J, Hoch B, Kellner W, Kelly JW, Schmidt A, Thomas PJ, Matsumura Y, Skach WR, Gentzsch M, Riordan JR, ... ... Gottesfeld JM, et al. Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nature Chemical Biology. 6: 25-33. PMID 19966789 DOI: 10.1038/Nchembio.275 |
0.307 |
|
| 2010 |
Minoshima M, Chou JC, Lefebvre S, Bando T, Shinohara K, Gottesfeld JM, Sugiyama H. Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes. Bioorganic & Medicinal Chemistry. 18: 168-74. PMID 19962902 DOI: 10.1016/J.Bmc.2009.11.005 |
0.459 |
|
| 2009 |
Gottesfeld JM, Pandolfo M. Development of histone deacetylase inhibitors as therapeutics for neurological disease. Future Neurology. 4: 775-784. PMID 20177429 DOI: 10.2217/Fnl.09.55 |
0.402 |
|
| 2009 |
Xu C, Soragni E, Chou CJ, Herman D, Plasterer HL, Rusche JR, Gottesfeld JM. Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chemistry & Biology. 16: 980-9. PMID 19778726 DOI: 10.1016/J.Chembiol.2009.07.010 |
0.389 |
|
| 2008 |
Chou CJ, O'Hare T, Lefebvre S, Alvarez D, Tyner JW, Eide CA, Druker BJ, Gottesfeld JM. Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate. Plos One. 3: e3593. PMID 18974832 DOI: 10.1371/Journal.Pone.0003593 |
0.308 |
|
| 2008 |
Chou CJ, Herman D, Gottesfeld JM. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. The Journal of Biological Chemistry. 283: 35402-9. PMID 18953021 DOI: 10.1074/Jbc.M807045200 |
0.345 |
|
| 2008 |
Thomas EA, Coppola G, Desplats PA, Tang B, Soragni E, Burnett R, Gao F, Fitzgerald KM, Borok JF, Herman D, Geschwind DH, Gottesfeld JM. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 15564-9. PMID 18829438 DOI: 10.1073/Pnas.0804249105 |
0.689 |
|
| 2008 |
Soragni E, Herman D, Dent SY, Gottesfeld JM, Wells RD, Napierala M. Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia. Nucleic Acids Research. 36: 6056-65. PMID 18820300 DOI: 10.1093/Nar/Gkn604 |
0.429 |
|
| 2008 |
Minoshima M, Chou J, Lefebvre S, Bando T, Shinohara K, Gottesfeld JM, Sugiyama H. Targeting specific gene by alkylating pyrrole-imidazole polyamides. Nucleic Acids Symposium Series (2004). 363-4. PMID 18776404 DOI: 10.1093/nass/nrn183 |
0.325 |
|
| 2008 |
Rai M, Soragni E, Jenssen K, Burnett R, Herman D, Coppola G, Geschwind DH, Gottesfeld JM, Pandolfo M. HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model. Plos One. 3: e1958. PMID 18463734 DOI: 10.1371/Journal.Pone.0001958 |
0.71 |
|
| 2008 |
Chou CJ, Farkas ME, Tsai SM, Alvarez D, Dervan PB, Gottesfeld JM. Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia. Molecular Cancer Therapeutics. 7: 769-78. PMID 18413791 DOI: 10.1158/1535-7163.Mct-08-0130 |
0.627 |
|
| 2008 |
Rai M, Soragni E, Jenssen K, Burnett R, Herman D, Coppola G, Geschwind DH, Gottesfeld JM, Pandolfo M. Effects of HDAC inhibitor 106 on frataxin mRNA and protein levels and on histone acetylation in KIKI mice. Plos One. DOI: 10.1371/Journal.Pone.0001958.G003 |
0.31 |
|
| 2007 |
Gottesfeld JM. Small molecules affecting transcription in Friedreich ataxia. Pharmacology & Therapeutics. 116: 236-48. PMID 17826840 DOI: 10.1016/J.Pharmthera.2007.06.014 |
0.374 |
|
| 2007 |
Tsai SM, Farkas ME, Chou CJ, Gottesfeld JM, Dervan PB. Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates. Nucleic Acids Research. 35: 307-16. PMID 17170006 DOI: 10.1093/Nar/Gkl1025 |
0.592 |
|
| 2007 |
Herman D, Jenssen K, Burnett R, Soragni E, Perlman SL, Gottesfeld JM. Erratum: Corrigendum: Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia Nature Chemical Biology. 3: 432-432. DOI: 10.1038/Nchembio0707-432 |
0.337 |
|
| 2006 |
Herman D, Jenssen K, Burnett R, Soragni E, Perlman SL, Gottesfeld JM. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nature Chemical Biology. 2: 551-8. PMID 16921367 DOI: 10.1038/Nchembio815 |
0.701 |
|
| 2006 |
Alvarez D, Chou CJ, Latella L, Zeitlin SG, Ku S, Puri PL, Dervan PB, Gottesfeld JM. A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate. Cell Cycle (Georgetown, Tex.). 5: 1537-48. PMID 16861886 DOI: 10.4161/Cc.5.14.2913 |
0.777 |
|
| 2006 |
Burnett R, Melander C, Puckett JW, Son LS, Wells RD, Dervan PB, Gottesfeld JM. DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia. Proceedings of the National Academy of Sciences of the United States of America. 103: 11497-502. PMID 16857735 DOI: 10.1073/Pnas.0604939103 |
0.837 |
|
| 2006 |
Trzupek JD, Gottesfeld JM, Boger DL. Alkylation of duplex DNA in nucleosome core particles by duocarmycin SA and yatakemycin. Nature Chemical Biology. 2: 79-82. PMID 16415862 DOI: 10.1038/Nchembio761 |
0.434 |
|
| 2006 |
Lee BM, Xu J, Clarkson BK, Martinez-Yamout MA, Dyson HJ, Case DA, Gottesfeld JM, Wright PE. Induced fit and "lock and key" recognition of 5S RNA by zinc fingers of transcription factor IIIA. Journal of Molecular Biology. 357: 275-91. PMID 16405997 DOI: 10.1016/J.Jmb.2005.12.010 |
0.379 |
|
| 2006 |
Raï M, Gottesfeld J, Dervan P, Pandolfo M. T.P.2 09 Overcoming the transcription defect in Friedreich ataxia with designed DNA ligands Neuromuscular Disorders. 16: 705-706. DOI: 10.1016/J.Nmd.2006.05.201 |
0.361 |
|
| 2006 |
Dickinson LA, Burnett R, Melander C, Edelson BS, Arora PS, Dervan PB, Gottesfeld JM. Arresting Cancer Proliferation by Small-Molecule Gene Regulation (DOI:10.1016/j.chembiol.2004.09.004) Chemistry and Biology. 13: 339. DOI: 10.1016/J.Chembiol.2006.02.006 |
0.714 |
|
| 2005 |
Gearhart MD, Dickinson L, Ehley J, Melander C, Dervan PB, Wright PE, Gottesfeld JM. Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides. Biochemistry. 44: 4196-203. PMID 15766247 DOI: 10.1021/Bi047872O |
0.753 |
|
| 2005 |
Beltran AC, Dawson PE, Gottesfeld JM. Role of DNA sequence in the binding specificity of synthetic basic-helix-loop-helix domains. Chembiochem : a European Journal of Chemical Biology. 6: 104-13. PMID 15593070 DOI: 10.1002/Cbic.200400184 |
0.792 |
|
| 2005 |
Edayathumangalam RS, Weyermann P, Dervan PB, Gottesfeld JM, Luger K. Nucleosomes in solution exist as a mixture of twist-defect states. Journal of Molecular Biology. 345: 103-14. PMID 15567414 DOI: 10.1016/J.Jmb.2004.10.012 |
0.662 |
|
| 2004 |
Dickinson LA, Burnett R, Melander C, Edelson BS, Arora PS, Dervan PB, Gottesfeld JM. Arresting cancer proliferation by small-molecule gene regulation. Chemistry & Biology. 11: 1583-94. PMID 15556009 DOI: 10.1016/J.Chembiol.2004.09.004 |
0.801 |
|
| 2004 |
Melander C, Burnett R, Gottesfeld JM. Regulation of gene expression with pyrrole-imidazole polyamides. Journal of Biotechnology. 112: 195-220. PMID 15288953 DOI: 10.1016/J.Jbiotec.2004.03.018 |
0.816 |
|
| 2004 |
Edayathumangalam RS, Weyermann P, Gottesfeld JM, Dervan PB, Luger K. Molecular recognition of the nucleosomal "supergroove". Proceedings of the National Academy of Sciences of the United States of America. 101: 6864-9. PMID 15100411 DOI: 10.1073/Pnas.0401743101 |
0.703 |
|
| 2003 |
Dudouet B, Burnett R, Dickinson LA, Wood MR, Melander C, Belitsky JM, Edelson B, Wurtz N, Briehn C, Dervan PB, Gottesfeld JM. Accessibility of nuclear chromatin by DNA binding polyamides. Chemistry & Biology. 10: 859-67. PMID 14522056 DOI: 10.1016/J.Chembiol.2003.09.001 |
0.839 |
|
| 2003 |
Gottesfeld JM, Barbas CF. RNA as a transcriptional activator. Chemistry & Biology. 10: 584-5. PMID 12890529 DOI: 10.1016/S1074-5521(03)00153-4 |
0.363 |
|
| 2003 |
Suto RK, Edayathumangalam RS, White CL, Melander C, Gottesfeld JM, Dervan PB, Luger K. Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. Journal of Molecular Biology. 326: 371-80. PMID 12559907 DOI: 10.1016/S0022-2836(02)01407-9 |
0.749 |
|
| 2002 |
Gottesfeld JM, Belitsky JM, Melander C, Dervan PB, Luger K. Blocking transcription through a nucleosome with synthetic DNA ligands. Journal of Molecular Biology. 321: 249-63. PMID 12144782 DOI: 10.1016/S0022-2836(02)00598-3 |
0.786 |
|
| 2002 |
Ehley JA, Melander C, Herman D, Baird EE, Ferguson HA, Goodrich JA, Dervan PB, Gottesfeld JM. Promoter scanning for transcription inhibition with DNA-binding polyamides. Molecular and Cellular Biology. 22: 1723-33. PMID 11865052 DOI: 10.1128/Mcb.22.6.1723-1733.2002 |
0.787 |
|
| 2002 |
Luger K, Suto RK, Edayathumangalam R, Gottesfeld J, Melander C, Dervan PB. Structural basis for site-specific recognition of nucleosomal DNA Acta Crystallographica Section a Foundations of Crystallography. 58: c35-c35. DOI: 10.1107/S0108767302086506 |
0.628 |
|
| 2001 |
Gottesfeld JM, Luger K. Energetics and affinity of the histone octamer for defined DNA sequences. Biochemistry. 40: 10927-33. PMID 11551187 DOI: 10.1021/Bi0109966 |
0.455 |
|
| 2001 |
Gottesfeld JM, Melander C, Suto RK, Raviol H, Luger K, Dervan PB. Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides. Journal of Molecular Biology. 309: 615-29. PMID 11397084 DOI: 10.1006/Jmbi.2001.4694 |
0.771 |
|
| 2001 |
Turner JM, Gottesfeld JM. Regulation of gene expression with synthetic DNA-binding ligands Chemtracts. 14: 563-572. |
0.353 |
|
| 2000 |
Gottesfeld JM, Turner JM, Dervan PB. Chemical approaches to control gene expression. Gene Expression. 9: 77-91. PMID 11097426 DOI: 10.3727/000000001783992696 |
0.685 |
|
| 2000 |
Winston RL, Ehley JA, Baird EE, Dervan PB, Gottesfeld JM. Asymmetric DNA binding by a homodimeric bHLH protein. Biochemistry. 39: 9092-8. PMID 10924102 DOI: 10.1021/Bi000947D |
0.814 |
|
| 2000 |
Winston RL, Gottesfeld JM. Rapid identification of key amino-acid-DNA contacts through combinatorial peptide synthesis. Chemistry & Biology. 7: 245-51. PMID 10780928 DOI: 10.1016/S1074-5521(00)00099-5 |
0.792 |
|
| 1999 |
Dickinson LA, Trauger JW, Baird EE, Ghazal P, Dervan PB, Gottesfeld JM. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides. Biochemistry. 38: 10801-7. PMID 10451376 DOI: 10.1021/Bi9912847 |
0.71 |
|
| 1999 |
Neely LS, Lee BM, Xu J, Wright PE, Gottesfeld JM. Identification of a minimal domain of 5 S ribosomal RNA sufficient for high affinity interactions with the RNA-specific zinc fingers of transcription factor IIIA. Journal of Molecular Biology. 291: 549-60. PMID 10448036 DOI: 10.1006/Jmbi.1999.2985 |
0.388 |
|
| 1999 |
Winston RL, Millar DP, Gottesfeld JM, Kent SB. Characterization of the DNA binding properties of the bHLH domain of Deadpan to single and tandem sites. Biochemistry. 38: 5138-46. PMID 10213619 DOI: 10.1021/Bi982856A |
0.797 |
|
| 1999 |
Dickinson LA, Trauger JW, Baird EE, Dervan PB, Graves BJ, Gottesfeld JM. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. The Journal of Biological Chemistry. 274: 12765-73. PMID 10212261 DOI: 10.1074/jbc.274.18.12765 |
0.66 |
|
| 1999 |
McBryant SJ, Baird EE, Trauger JW, Dervan PB, Gottesfeld JM. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand. Journal of Molecular Biology. 286: 973-81. PMID 10047474 DOI: 10.1006/Jmbi.1999.2539 |
0.728 |
|
| 1998 |
Dickinson LA, Gulizia RJ, Trauger JW, Baird EE, Mosier DE, Gottesfeld JM, Dervan PB. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands. Proceedings of the National Academy of Sciences of the United States of America. 95: 12890-5. PMID 9789010 DOI: 10.1073/Pnas.95.22.12890 |
0.726 |
|
| 1998 |
Long JJ, Leresche A, Kriwacki RW, Gottesfeld JM. Repression of TFIIH transcriptional activity and TFIIH-associated cdk7 kinase activity at mitosis. Molecular and Cellular Biology. 18: 1467-76. PMID 9488463 DOI: 10.1128/Mcb.18.3.1467 |
0.384 |
|
| 1997 |
McBryant SJ, Gottesfeld JM. Differential kinetics of transcription complex assembly distinguish oocyte and somatic 5S RNA genes of Xenopus. Gene Expression. 6: 387-99. PMID 9495319 |
0.369 |
|
| 1997 |
Neely L, Trauger JW, Baird EE, Dervan PB, Gottesfeld JM. Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex. Journal of Molecular Biology. 274: 439-45. PMID 9417925 DOI: 10.1006/Jmbi.1997.1411 |
0.717 |
|
| 1997 |
Wuttke DS, Foster MP, Case DA, Gottesfeld JM, Wright PE. Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity. Journal of Molecular Biology. 273: 183-206. PMID 9367756 DOI: 10.1006/Jmbi.1997.1291 |
0.447 |
|
| 1997 |
Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE. Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA. Nature Structural Biology. 4: 605-8. PMID 9253405 DOI: 10.1038/Nsb0897-605 |
0.438 |
|
| 1997 |
Gottesfeld JM, Forbes DJ. Mitotic repression of the transcriptional machinery Trends in Biochemical Sciences. 22: 197-202. PMID 9204705 DOI: 10.1016/S0968-0004(97)01045-1 |
0.437 |
|
| 1997 |
Gottesfeld JM, Neely L, Trauger JW, Baird EE, Dervan PB. Regulation of gene expression by small molecules. Nature. 387: 202-5. PMID 9144294 DOI: 10.1038/387202A0 |
0.737 |
|
| 1996 |
Leresche A, Wolf VJ, Gottesfeld JM. Repression of RNA polymerase II and III transcription during M phase of the cell cycle. Experimental Cell Research. 229: 282-8. PMID 8986611 DOI: 10.1006/Excr.1996.0373 |
0.419 |
|
| 1996 |
Brown ML, Schroth GP, Gottesfeld JM, Bazett-Jones DP. Protein and DNA requirements for the transcription factor IIIA-induced distortion of the 5 S rRNA gene promoter Journal of Molecular Biology. 262: 600-614. PMID 8876641 DOI: 10.1006/Jmbi.1996.0539 |
0.526 |
|
| 1996 |
McBryant SJ, Meier E, Leresche A, Sharp SJ, Wolf VJ, Gottesfeld JM. TATA-box DNA binding activity and subunit composition for RNA polymerase III transcription factor IIIB from Xenopus laevis. Molecular and Cellular Biology. 16: 4639-47. PMID 8756620 DOI: 10.1128/Mcb.16.9.4639 |
0.505 |
|
| 1996 |
McBryant SJ, Gedulin B, Clemens KR, Wright PE, Gottesfeld JM. Assessment of major and minor groove DNA interactions by the zinc fingers of Xenopus transcription factor IIIA. Nucleic Acids Research. 24: 2567-74. PMID 8692697 DOI: 10.1093/Nar/24.13.2567 |
0.483 |
|
| 1996 |
Gottesfeld JM, Johnson DL, Nyborg JK. Transcriptional activation of RNA polymerase III-dependent genes by the human T-cell leukemia virus type 1 Tax protein Molecular and Cellular Biology. 16: 1777-1785. PMID 8657153 DOI: 10.1128/Mcb.16.4.1777 |
0.447 |
|
| 1995 |
McBryant SJ, Kassavetis GA, Gottesfeld JM. Repression of vertebrate RNA polymerase III transcription by DNA binding proteins located upstream from the transcription start site. Journal of Molecular Biology. 250: 315-26. PMID 7608977 DOI: 10.1006/Jmbi.1995.0379 |
0.48 |
|
| 1994 |
Gottesfeld JM, Wolf VJ, Dang T, Forbes DJ, Hartl P. Mitotic repression of RNA polymerase III transcription in vitro mediated by phosphorylation of a TFIIIB component. Science (New York, N.Y.). 263: 81-4. PMID 8272869 DOI: 10.1126/Science.8272869 |
0.38 |
|
| 1994 |
Wolf VJ, Dang T, Hartl P, Gottesfeld JM. Role of maturation-promoting factor (p34cdc2-cyclin B) in differential expression of the Xenopus oocyte and somatic-type 5S RNA genes. Molecular and Cellular Biology. 14: 4704-11. PMID 8007972 DOI: 10.1128/Mcb.14.7.4704 |
0.455 |
|
| 1994 |
Clemens KR, Zhang P, Liao X, McBryant SJ, Wright PE, Gottesfeld JM. Relative contributions of the zinc fingers of transcription factor IIIA to the energetics of DNA binding. Journal of Molecular Biology. 244: 23-35. PMID 7966319 DOI: 10.1006/Jmbi.1994.1701 |
0.496 |
|
| 1993 |
Clemens KR, Wolf V, McBryant SJ, Zhang P, Liao X, Wright PE, Gottesfeld JM. Molecular basis for specific recognition of both RNA and DNA by a zinc finger protein. Science (New York, N.Y.). 260: 530-3. PMID 8475383 DOI: 10.1126/Science.8475383 |
0.453 |
|
| 1993 |
Hartl P, Gottesfeld J, Forbes DJ. Mitotic repression of transcription in vitro. The Journal of Cell Biology. 120: 613-24. PMID 8381119 DOI: 10.1083/Jcb.120.3.613 |
0.428 |
|
| 1992 |
Liao XB, Clemens KR, Tennant L, Wright PE, Gottesfeld JM. Specific interaction of the first three zinc fingers of TFIIIA with the internal control region of the Xenopus 5 S RNA gene. Journal of Molecular Biology. 223: 857-71. PMID 1538401 DOI: 10.1016/0022-2836(92)90248-I |
0.497 |
|
| 1992 |
Keller HJ, Romaniuk PJ, Gottesfeld JM. Interaction of Xenopus TFIIIC with the TFIIIA.5 S RNA gene complex. The Journal of Biological Chemistry. 267: 18190-8. PMID 1517247 |
0.373 |
|
| 1992 |
Clemens KR, Liao X, Wolf V, Wright PE, Gottesfeld JM. Definition of the binding sites of individual zinc fingers in the transcription factor IIIA-5S RNA gene complex. Proceedings of the National Academy of Sciences of the United States of America. 89: 10822-6. PMID 1438283 DOI: 10.1073/Pnas.89.22.10822 |
0.469 |
|
| 1991 |
Schroth GP, Gottesfeld JM, Bradbury EM. TFIIIA induced DNA bending: Effect of low ionic strength electrophoresis buffer conditions Nucleic Acids Research. 19: 511-516. PMID 2011525 DOI: 10.1093/Nar/19.3.511 |
0.465 |
|
| 1991 |
Lee MS, Gottesfeld JM, Wright PE. Zinc is required for folding and binding of a single zinc finger to DNA. Febs Letters. 279: 289-94. PMID 2001741 DOI: 10.1016/0014-5793(91)80170-8 |
0.385 |
|
| 1990 |
Keller HJ, You QM, Romaniuk PJ, Gottesfeld JM. Additional intragenic promoter elements of the Xenopus 5S RNA genes upstream from the TFIIIA-binding site. Molecular and Cellular Biology. 10: 5166-76. PMID 2398887 DOI: 10.1128/Mcb.10.10.5166 |
0.461 |
|
| 1990 |
Engelke DR, Gottesfeld JM. Chromosomal footprinting of transcriptionally active and inactive oocyte-type 5S RNA genes of Xenopus laevis. Nucleic Acids Research. 18: 6031-7. PMID 2235485 DOI: 10.1093/Nar/18.20.6031 |
0.49 |
|
| 1989 |
Gottesfeld JM. Analysis of RNA polymerase III transcription in vitro using chromatin and cloned gene templates. Methods in Enzymology. 170: 347-59. PMID 2770545 DOI: 10.1016/0076-6879(89)70055-0 |
0.453 |
|
| 1989 |
Schroth GP, Cook GR, Bradbury EM, Gottesfeld JM. Transcription factor IIIA induced bending of the Xenopus somatic 5S gene promoter. Nature. 340: 487-8. PMID 2755511 DOI: 10.1038/340487A0 |
0.518 |
|
| 1989 |
Millstein LS, Gottesfeld JM. Control of gene expression in eukaryotic cells: lessons from class III genes Current Opinion in Cell Biology. 1: 497-502. PMID 2697269 DOI: 10.1016/0955-0674(89)90011-2 |
0.784 |
|
| 1989 |
Blanco J, Millstein L, Razik MA, Dilworth S, Cote C, Gottesfeld J. Two TFIIIA activities regulate expression of the Xenopus 5S RNA gene families. Genes & Development. 3: 1602-12. PMID 2575558 DOI: 10.1101/Gad.3.10.1602 |
0.803 |
|
| 1989 |
Razik MA, Blanco J, Gottesfeld JM. Pathways of nucleoprotein assembly on 5S RNA genes in a Xenopus oocyte S-150 extract. Nucleic Acids Research. 17: 4117-30. PMID 2544856 DOI: 10.1093/Nar/17.11.4117 |
0.489 |
|
| 1988 |
Blanco J, Gottesfeld JM. Xenopus transcription factor IIIA forms a complex of covalent character with 5S DNA. Nucleic Acids Research. 16: 11267-84. PMID 3205743 DOI: 10.1093/Nar/16.23.11267 |
0.457 |
|
| 1987 |
Peck LJ, Millstein L, Eversole-Cire P, Gottesfeld JM, Varshavsky A. Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro. Molecular and Cellular Biology. 7: 3503-10. PMID 3683391 DOI: 10.1128/Mcb.7.10.3503 |
0.793 |
|
| 1987 |
Gottesfeld JM, Blanco J, Tennant LL. The 5S gene internal control region is B-form both free in solution and in a complex with TFIIIA. Nature. 329: 460-2. PMID 3657961 DOI: 10.1038/329460A0 |
0.495 |
|
| 1987 |
Gottesfeld JM. DNA sequence-directed nucleosome reconstitution on 5S RNA genes of Xenopus laevis. Molecular and Cellular Biology. 7: 1612-22. PMID 3600640 DOI: 10.1128/Mcb.7.5.1612 |
0.53 |
|
| 1987 |
Millstein L, Eversole-Cire P, Blanco J, Gottesfeld JM. Differential transcription of Xenopus oocyte and somatic-type 5 S genes in a Xenopus oocyte extract. The Journal of Biological Chemistry. 262: 17100-10. PMID 2445754 |
0.352 |
|
| 1986 |
Gottesfeld JM. Novobiocin inhibits RNA polymerase III transcription in vitro by a mechanism distinct from DNA topoisomerase II. Nucleic Acids Research. 14: 2075-88. PMID 3008085 DOI: 10.1093/Nar/14.5.2075 |
0.473 |
|
| 1985 |
Reynolds WF, Gottesfeld JM. Torsional stress induces an S1 nuclease-hypersensitive site within the promoter of the Xenopus laevis oocyte-type 5S RNA gene. Proceedings of the National Academy of Sciences of the United States of America. 82: 4018-22. PMID 2987960 DOI: 10.1073/Pnas.82.12.4018 |
0.454 |
|
| 1985 |
Bazett-Jones DP, Yeckel M, Gottesfeld JM. Nuclear extracts from globin-synthesizing cells enhance globin transcription in vitro. Nature. 317: 824-8. PMID 2414668 DOI: 10.1038/317824A0 |
0.492 |
|
| 1984 |
Sutcliffe JG, Milner RJ, Gottesfeld JM, Reynolds W. Control of neuronal gene expression. Science (New York, N.Y.). 225: 1308-15. PMID 6474179 DOI: 10.1126/Science.6474179 |
0.428 |
|
| 1984 |
von Beroldingen CH, Reynolds WF, Millstein L, Bazett-Jones DP, Gottesfeld JM. Eukaryotic transcription complexes. Molecular and Cellular Biochemistry. 62: 97-108. PMID 6379414 DOI: 10.1007/Bf00223300 |
0.819 |
|
| 1984 |
Gottesfeld JM, Andrews DL, Hoch SO. Association of an RNA polymerase III transcription factor with a ribonucleoprotein complex recognized by autoimmune sera. Nucleic Acids Research. 12: 3185-200. PMID 6232502 DOI: 10.1093/Nar/12.7.3185 |
0.395 |
|
| 1984 |
Sutcliffe JG, Milner RJ, Gottesfeld JM, Lerner RA. Identifier sequences are transcribed specifically in brain. Nature. 308: 237-41. PMID 6199680 DOI: 10.1038/308237A0 |
0.379 |
|
| 1984 |
Andrews DL, Millstein L, Hamkalo BA, Gottesfeld JM. Competition between Xenopus satellite I sequences and Pol III genes for stable transcription complex formation. Nucleic Acids Research. 12: 7753-69. PMID 6093052 DOI: 10.1093/Nar/12.20.7753 |
0.826 |
|
| 1983 |
Reynolds WF, Bloomer LS, Gottesfeld JM. Control of 5S RNA transcription in Xenopus somatic cell chromatin: activation with an oocyte extract. Nucleic Acids Research. 11: 57-75. PMID 6866764 DOI: 10.1093/Nar/11.1.57 |
0.464 |
|
| 1983 |
Reynolds WF, Gottesfeld JM. 5S rRNA gene transcription factor IIIA alters the helical configuration of DNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 1862-6. PMID 6572947 DOI: 10.1073/Pnas.80.7.1862 |
0.514 |
|
| 1982 |
Gottesfeld J, Bloomer LS. Assembly of transcriptionally active 5S RNA gene chromatin in vitro. Cell. 28: 781-91. PMID 7201351 DOI: 10.1016/0092-8674(82)90057-5 |
0.492 |
|
| 1980 |
Gottesfeld JM, Bloomer LS. Nonrandom alignment of nucleosomes on 5S RNA genes of X. laevis Cell. 21: 751-760. PMID 7438206 DOI: 10.1016/0092-8674(80)90438-9 |
0.525 |
|
| 1978 |
Gottesfeld JM, Melton DA. The length of nucleosome-associated DNA is the same in both transcribed and nontranscribed regions of chromatin. Nature. 273: 317-9. PMID 652040 DOI: 10.1038/273317A0 |
0.481 |
|
| 1978 |
Gottesfeld JM. Organization of transcribed regions of chromatin Philosophical Transactions of the Royal Society of London Series B Biological Sciences. 283: 343-357. PMID 26080 DOI: 10.1098/Rstb.1978.0036 |
0.45 |
|
| 1977 |
Gottesfeld JM, Butler PJG. Structure of transcriptionally-active chromatin subunits Nucleic Acids Research. 4: 3155-3174. PMID 909802 DOI: 10.1093/Nar/4.9.3155 |
0.44 |
|
| 1977 |
Gottesfeld JM, Partington GA. Distribution of messenger RNA-coding sequences in fractionated chromatin Cell. 12: 953-962. PMID 597865 DOI: 10.1016/0092-8674(77)90160-X |
0.419 |
|
| 1977 |
Gottesfeld JM. Methods for fractionation of chromatin into transcriptionally active and inactive segments Methods in Cell Biology. 16: 421-436. PMID 329060 DOI: 10.1016/S0091-679X(08)60117-X |
0.363 |
|
| 1976 |
Gottesfeld JM, Bagi G, Berg B, Bonner J. Sequence composition of the template-active fraction of rat liver chromatin Biochemistry. 15: 2472-2483. PMID 179568 DOI: 10.1021/Bi00656A034 |
0.578 |
|
| 1975 |
Gottesfeld JM, Murphy RF, Bonner J. Structure of transcriptionally active chromatin Proceedings of the National Academy of Sciences of the United States of America. 72: 4404-4408. PMID 1060119 DOI: 10.1073/Pnas.72.11.4404 |
0.594 |
|
| 1975 |
Bonner J, Gottesfeld J, Garrard W, Billing R, Uphouse L. [8] Isolation of template active and inactive regions of chromatin Methods in Enzymology. 40: 97-102. PMID 164611 DOI: 10.1016/S0076-6879(75)40010-6 |
0.566 |
|
| 1974 |
Gottesfeld JM, Garrard WT, Bagi G, Wilson RF, Bonner J. Partial purification of the template active fraction of chromatin: a preliminary report Proceedings of the National Academy of Sciences of the United States of America. 71: 2193-2197. PMID 4526205 DOI: 10.1073/Pnas.71.6.2193 |
0.632 |
|
| 1974 |
Bonner J, Garrard WT, Gottesfeld J, Holmes DS. Functional organization of the mammalian genome. Cold Spring Harbor Symposia On Quantitative Biology. 38: 303-10. PMID 4524761 DOI: 10.1101/Sqb.1974.038.01.034 |
0.459 |
|
| 1971 |
Gottesfeld JM, Adams NH, el-Badry AM, Moses V, Calvin M. The inhibition of deoxyribonuclease I by hydroxybiphenyls. Biochimica Et Biophysica Acta. 228: 365-86. PMID 5101930 DOI: 10.1016/0005-2787(71)90044-X |
0.325 |
|
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