| Year |
Citation |
Score |
| 1997 |
Summers KL, Kem WR, Giacobini E. Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex. Japanese Journal of Pharmacology. 74: 139-46. PMID 9243321 DOI: 10.1254/Jjp.74.139 |
0.389 |
|
| 1996 |
Giacobini E. New trends in cholinergic therapy for Alzheimer disease: nicotinic agonists or cholinesterase inhibitors? Progress in Brain Research. 109: 311-23. PMID 9009719 DOI: 10.1016/S0079-6123(08)62114-7 |
0.402 |
|
| 1996 |
Summers KL, Lippiello P, Giacobini E. A microdialysis study of the effects of the nicotinic agonist RJR-2403 on cortical release of acetylcholine and biogenic amines. Neurochemical Research. 21: 1181-6. PMID 8923478 DOI: 10.1007/Bf02532393 |
0.366 |
|
| 1996 |
Zhu XD, Cuadra G, Brufani M, Maggi T, Pagella PG, Williams E, Giacobini E. Effects of MF-268, a new cholinesterase inhibitor, on acetylcholine and biogenic amines in rat cortex. Journal of Neuroscience Research. 43: 120-6. PMID 8838583 DOI: 10.1002/Jnr.490430116 |
0.346 |
|
| 1996 |
Giacobini E, Zhu X D, Williams E, Sherman KA. The effect of the selective reversible acetylcholinesterase inhibitor E2020 on extracellular acetylcholine and biogenic amine levels in rat cortex. Neuropharmacology. 35: 205-11. PMID 8734490 DOI: 10.1016/0028-3908(95)00157-3 |
0.392 |
|
| 1995 |
Summers KL, Lippiello P, Verhulst S, Giacobini E. 5-fluoronicotine, noranhydroecgonine, and pyridyl-methylpyrrolidine release acetylcholine and biogenic amines in rat cortex in vivo. Neurochemical Research. 20: 1089-94. PMID 8570014 DOI: 10.1007/Bf00995564 |
0.359 |
|
| 1995 |
Mori F, Cuadra G, Giacobini E. Metrifonate effects on acetylcholine and biogenic amines in rat cortex. Neurochemical Research. 20: 1081-8. PMID 8570013 DOI: 10.1007/Bf00995563 |
0.375 |
|
| 1995 |
Zhu XD, Giacobini E, Hornsperger JM. Effect of MDL 73,745 on acetylcholine and biogenic amine levels in rat cortex. European Journal of Pharmacology. 276: 93-9. PMID 7781701 DOI: 10.1016/0014-2999(95)00014-C |
0.365 |
|
| 1995 |
Mori F, Lai CC, Fusi F, Giacobini E. Cholinesterase inhibitors increase secretion of APPs in rat brain cortex. Neuroreport. 6: 633-6. PMID 7605915 DOI: 10.1097/00001756-199503000-00012 |
0.372 |
|
| 1995 |
Summers KL, Giacobini E. Effects of local and repeated systemic administration of (-)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex. Neurochemical Research. 20: 753-9. PMID 7566373 DOI: 10.1007/Bf01705545 |
0.389 |
|
| 1995 |
Zhu XD, Giacobini E. Second generation cholinesterase inhibitors: effect of (L)-huperzine-A on cortical biogenic amines. Journal of Neuroscience Research. 41: 828-35. PMID 7500384 DOI: 10.1002/Jnr.490410613 |
0.366 |
|
| 1994 |
Giacobini E. Therapy for Alzheimer's disease. Symptomatic or neuroprotective? Molecular Neurobiology. 9: 115-8. PMID 7888087 DOI: 10.1007/Bf02816110 |
0.303 |
|
| 1994 |
Summers KL, Cuadra G, Naritoku D, Giacobini E. Effects of nicotine on levels of acetylcholine and biogenic amines in rat cortex Drug Development Research. 31: 108-119. DOI: 10.1002/Ddr.430310205 |
0.391 |
|
| 1993 |
Messamore E, Ogane N, Giacobini E. Cholinesterase inhibitor effects on extracellular acetylcholine in rat striatum. Neuropharmacology. 32: 291-6. PMID 8474626 DOI: 10.1016/0028-3908(93)90114-I |
0.35 |
|
| 1993 |
Giacobini E. Pharmacotherapy of Alzheimer disease: new drugs and novel strategies. Progress in Brain Research. 98: 447-54. PMID 8248535 DOI: 10.1016/S0079-6123(08)62431-0 |
0.312 |
|
| 1993 |
Messamore E, Warpman U, Williams E, Giacobini E. Muscarinic receptors mediate attenuation of extracellular acetylcholine levels in rat cerebral cortex after cholinesterase inhibition. Neuroscience Letters. 158: 205-8. PMID 8233096 DOI: 10.1016/0304-3940(93)90265-M |
0.374 |
|
| 1992 |
Linville DG, Giacobini E, Arnerić SP. Heptyl-physostigmine enhances basal forebrain control of cortical cerebral blood flow. Journal of Neuroscience Research. 31: 573-7. PMID 1640506 DOI: 10.1002/Jnr.490310323 |
0.326 |
|
| 1992 |
Ogane N, Giacobini E, Messamore E. Preferential inhibition of acetylcholinesterase molecular forms in rat brain. Neurochemical Research. 17: 489-95. PMID 1528356 DOI: 10.1007/Bf00969897 |
0.343 |
|
| 1992 |
Ogane N, Giacobini E, Struble R. Differential inhibition of acetylcholinesterase molecular forms in normal and Alzheimer disease brain. Brain Research. 589: 307-12. PMID 1393597 DOI: 10.1016/0006-8993(92)91291-L |
0.344 |
|
| 1992 |
Messamore E, Warpman U, Summers K, Giacobini E. Muscarinic regulation of extracellular acetylcholine levels in vivo following cholinesterase inhibition Neurobiology of Aging. 13. DOI: 10.1016/0197-4580(92)90643-C |
0.327 |
|
| 1991 |
Schröder H, Giacobini E, Struble RG, Zilles K, Maelicke A. Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease. Neurobiology of Aging. 12: 259-62. PMID 1876232 DOI: 10.1016/0197-4580(91)90107-U |
0.369 |
|
| 1991 |
Giacobini E. Nicotinic cholinergic receptors in human brain: effects of aging and Alzheimer. Advances in Experimental Medicine and Biology. 296: 303-15. PMID 1781336 DOI: 10.1007/978-1-4684-8047-4_28 |
0.37 |
|
| 1991 |
Schröder H, Giacobini E, Struble RG, Zilles K, Maelicke A, Luiten PG, Strosberg AD. Cellular distribution and expression of cortical acetylcholine receptors in aging and Alzheimer's disease. Annals of the New York Academy of Sciences. 640: 189-92. PMID 1776738 DOI: 10.1111/J.1749-6632.1991.Tb00215.X |
0.361 |
|
| 1991 |
Schröder H, Giacobini E, Struble RG, Luiten PG, van der Zee EA, Zilles K, Strosberg AD. Muscarinic cholinoceptive neurons in the frontal cortex in Alzheimer's disease. Brain Research Bulletin. 27: 631-6. PMID 1756381 DOI: 10.1016/0361-9230(91)90038-L |
0.358 |
|
| 1991 |
Rakonczay Z, Matsuoka Y, Giacobini E. Effects of L-beta-N-methylamino-L-alanine (L-BMAA) on the cortical cholinergic and glutamatergic systems of the rat. Journal of Neuroscience Research. 29: 121-6. PMID 1653366 DOI: 10.1002/Jnr.490290114 |
0.338 |
|
| 1990 |
Scremin OU, Scremin AM, Somani SM, Giacobini E. Brain regional distribution of physostigmine and its relation to cerebral blood flow following intravenous administration in rats. Journal of Neuroscience Research. 26: 188-95. PMID 2366261 DOI: 10.1002/Jnr.490260208 |
0.323 |
|
| 1990 |
Manyam BV, Giacobini E, Colliver JA. Cerebrospinal fluid choline levels are decreased in Parkinson's disease. Annals of Neurology. 27: 683-5. PMID 2360805 DOI: 10.1002/Ana.410270616 |
0.349 |
|
| 1990 |
Giacobini E. The cholinergic system in Alzheimer disease. Progress in Brain Research. 84: 321-32. PMID 2267306 DOI: 10.1016/S0079-6123(08)60916-4 |
0.398 |
|
| 1990 |
Manyam BV, Giacobini E, Colliver JA. Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease. Journal of Neurology. 237: 281-4. PMID 2146369 DOI: 10.1007/Bf00314742 |
0.382 |
|
| 1990 |
Sugaya K, Giacobini E, Chiappinelli VA. Nicotinic acetylcholine receptor subtypes in human frontal cortex: changes in Alzheimer's disease. Journal of Neuroscience Research. 27: 349-59. PMID 2097379 DOI: 10.1002/Jnr.490270314 |
0.649 |
|
| 1990 |
Giacobini E. Cholinergic receptors in human brain: effects of aging and Alzheimer disease. Journal of Neuroscience Research. 27: 548-60. PMID 2079716 DOI: 10.1002/Jnr.490270416 |
0.343 |
|
| 1990 |
Becker RE, Colliver J, Elble R, Feldman E, Giacobini E, Kumar V, Markwell S, Moriearty P, Parks R, Shillcutt SD, Unni L, Vicari S, Womack C, Zec RF. Effects of metrifonate, a long-acting cholinesterase inhibitor, in Alzheimer disease: Report of an open trial Drug Development Research. 19: 425-434. DOI: 10.1002/Ddr.430190407 |
0.327 |
|
| 1989 |
Elble R, Giacobini E, Higgins C. Choline levels are increased in cerebrospinal fluid of Alzheimer patients. Neurobiology of Aging. 10: 45-50. PMID 2755556 DOI: 10.1016/S0197-4580(89)80009-0 |
0.339 |
|
| 1989 |
Hallak M, Giacobini E. Physostigmine, tacrine and metrifonate: the effect of multiple doses on acetylcholine metabolism in rat brain. Neuropharmacology. 28: 199-206. PMID 2725846 DOI: 10.1016/0028-3908(89)90093-2 |
0.385 |
|
| 1989 |
De Sarno P, Giacobini E. Modulation of acetylcholine release by nicotinic receptors in the rat brain. Journal of Neuroscience Research. 22: 194-200. PMID 2709442 DOI: 10.1002/Jnr.490220213 |
0.433 |
|
| 1989 |
Giacobini E, DeSarno P, Clark B, McIlhany M. The cholinergic receptor system of the human brain: neurochemical and pharmacological aspects in aging and Alzheimer. Progress in Brain Research. 79: 335-43. PMID 2685904 DOI: 10.1016/S0079-6123(08)62493-0 |
0.403 |
|
| 1989 |
De Sarno P, Pomponi M, Giacobini E, Tang XC, Williams E. The effect of heptyl-physostigmine, a new cholinesterase inhibitor, on the central cholinergic system of the rat. Neurochemical Research. 14: 971-7. PMID 2608162 DOI: 10.1007/Bf00965931 |
0.415 |
|
| 1989 |
Kumar V, Giacobini E, Markwell S. CSF choline and acetylcholinesterase in early-onset vs. late-onset Alzheimer's disease patients. Acta Neurologica Scandinavica. 80: 461-6. PMID 2589014 DOI: 10.1111/J.1600-0404.1989.Tb03910.X |
0.31 |
|
| 1989 |
Tang XC, De Sarno P, Sugaya K, Giacobini E. Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat. Journal of Neuroscience Research. 24: 276-85. PMID 2585551 DOI: 10.1002/Jnr.490240220 |
0.301 |
|
| 1988 |
Becker RE, Giacobini E. Mechanisms of cholinesterase inhibition in senile dementia of the Alzheimer type: Clinical, pharmacological, and therapeutic aspects Drug Development Research. 12: 163-195. DOI: 10.1002/Ddr.430120302 |
0.367 |
|
| 1987 |
Giacobini E, Somani S, McIlhany M, Downen M, Hallak M. Pharmacokinetics and pharmacodynamics of physostigmine after intravenous administration in beagle dogs. Neuropharmacology. 26: 831-6. PMID 3658115 DOI: 10.1016/0028-3908(87)90059-1 |
0.31 |
|
| 1987 |
Hallak M, Giacobini E. A comparison of the effects of two inhibitors on brain cholinesterase. Neuropharmacology. 26: 521-30. PMID 3601008 DOI: 10.1016/0028-3908(87)90143-2 |
0.396 |
|
| 1987 |
Giacobini E, Mattio T, Mussini I. Aging of cholinergic synapses in the avian iris. Part I--Biochemical studies. Neurobiology of Aging. 8: 123-9. PMID 3587489 DOI: 10.1016/0197-4580(87)90021-2 |
0.3 |
|
| 1987 |
De Sarno P, Giacobini E, Downen M. Release of acetylcholinesterase from the caudate nucleus of the rat. Journal of Neuroscience Research. 18: 578-90. PMID 3437472 DOI: 10.1002/Jnr.490180411 |
0.334 |
|
| 1987 |
Giacobini E. Modulation of brain acetylcholine levels with cholinesterase inhibitors as a treatment of Alzheimer disease. The Keio Journal of Medicine. 36: 381-91. PMID 3325681 DOI: 10.2302/Kjm.36.381 |
0.405 |
|
| 1986 |
Mattio T, McIlhany M, Giacobini E, Hallak M. The effects of physostigmine on acetylcholinesterase activity of CSF plasma and brain. A comparison of intravenous and intraventricular administration in beagle dogs. Neuropharmacology. 25: 1167-77. PMID 3785584 DOI: 10.1016/0028-3908(86)90166-8 |
0.396 |
|
| 1986 |
Hallak M, Giacobini E. Relation of brain regional physostigmine concentration to cholinesterase activity and acetylcholine and choline levels in rat. Neurochemical Research. 11: 1037-48. PMID 3748273 DOI: 10.1007/Bf00965592 |
0.385 |
|
| 1986 |
Kim JS, Gutierrez MC, Giacobini E, Sundberg JP. Experimental maternal hyperpipecolatemia decreases DNA in the mouse brain. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 4: 113-8. PMID 2458673 DOI: 10.1016/0736-5748(86)90035-3 |
0.33 |
|
| 1985 |
Kim JS, Giacobini E. Transport of pipecolic acid in adult and developing mouse brain. Neurochemical Research. 10: 1405-15. PMID 4069310 DOI: 10.1007/Bf00964981 |
0.323 |
|
| 1985 |
Kim JS, Giacobini E. Pipecolic acid levels and transport in developing mouse brain. Brain Research. 354: 181-6. PMID 4052811 DOI: 10.1016/0165-3806(85)90169-5 |
0.322 |
|
| 1985 |
Gutierrez MD, Giacobini E. Identification and characterization of pipecolic acid binding sites in mouse brain. Neurochemical Research. 10: 691-702. PMID 4010875 DOI: 10.1007/Bf00964407 |
0.313 |
|
| 1985 |
Mattio TG, Richardson JS, Giacobini E. Acute effects of cholinesterase inhibitors on uptake of choline in the rat iris. Neuropharmacology. 24: 325-8. PMID 4000406 DOI: 10.1016/0028-3908(85)90138-8 |
0.304 |
|
| 1984 |
Mattio TG, Richardson JS, Giacobini E. Effects of DFP on iridic metabolism and release of acetylcholine and on pupillary function in the rat. Neuropharmacology. 23: 1207-14. PMID 6521855 DOI: 10.1016/0028-3908(84)90241-7 |
0.361 |
|
| 1984 |
Richardson JS, Mattio TG, Giacobini E. Amitriptyline and imipramine inhibit the release of acetylcholine from parasympathetic nerve terminals in the rat iris. Canadian Journal of Physiology and Pharmacology. 62: 857-9. PMID 6498615 DOI: 10.1139/Y84-143 |
0.358 |
|
| 1979 |
Giacobini E, Pilar G, Suszkiw J, Uchimura H. Normal distribution and denervation changes of neurotransmitter related enzymes in cholinergic neurones. The Journal of Physiology. 286: 233-53. PMID 220412 DOI: 10.1113/Jphysiol.1979.Sp012616 |
0.597 |
|
| 1978 |
Scarsella G, Toschi G, Chiappinelli VA, Giacobini E. Molecular forms of acetylcholinesterase in the ciliary ganglion and iris of the chick. Developmental changes and effects of axotomy. Developmental Neuroscience. 1: 133-41. PMID 756378 DOI: 10.1159/000112565 |
0.617 |
|
| 1978 |
Chiappinelli VA, Giacobini E. Time course of appearance of alpha-bungarotoxin binding sites during development of chick ciliary ganglion and iris. Neurochemical Research. 3: 465-78. PMID 745659 DOI: 10.1007/BF00966328 |
0.607 |
|
| 1978 |
Chiappinelli VA, Fairman K, Giacobini E. Effects of nicotinic antagonists on the development of the chick lumbar sympathetic ganglia, ciliary ganglion and iris Developmental Neuroscience. 1: 191-202. DOI: 10.1159/000112574 |
0.637 |
|
| 1977 |
Fairman K, Chiappinelli V, Giacobini E, Yurkewicz L. The effect of a single dose of reserpine administered prior to incubation on the development of tyrosine hydroxylase activity in chick sympathetic ganglia. Brain Research. 122: 503-12. PMID 14767 DOI: 10.1016/0006-8993(77)90460-7 |
0.635 |
|
| 1976 |
Chiappinelli V, Giacobini E, Pilar G, Uchimura H. Induction of cholinergic enzymes in chick ciliary ganglion and iris muscle cells during synapse formation. The Journal of Physiology. 257: 749-66. PMID 181563 DOI: 10.1113/Jphysiol.1976.Sp011395 |
0.704 |
|
| 1976 |
Fairman K, Giacobini E, Chiappinelli V. Developmental variations of tyrosine hydroxylase and acetylcholinesterase in embryonic and post-hatching chicken sympathetic ganglia. Brain Research. 102: 301-12. PMID 2367 DOI: 10.1016/0006-8993(76)90884-2 |
0.616 |
|
| 1976 |
Giacobini E, Fairman K, Chiappinelli V, Yurkewicz L. The effect of reserpine on the development of tyrosine hydroxylase in chick sympathetic ganglia Trans.Amer.Soc.Neurochem.. 7: NO.30. |
0.601 |
|
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