| Year |
Citation |
Score |
| 2002 |
Ruan B, Lai PS, Yeh CW, Wilson WK, Pang J, Xu R, Matsuda SP, Schroepfer GJ. Alternative pathways of sterol synthesis in yeast. Use of C(27) sterol tracers to study aberrant double-bond migrations and evaluate their relative importance. Steroids. 67: 1109-19. PMID 12441197 DOI: 10.1016/S0039-128X(02)00069-7 |
0.348 |
|
| 2001 |
Lindenthal B, Holleran AL, Aldaghlas TA, Ruan B, Schroepfer GJ, Wilson WK, Kelleher JK. Progestins block cholesterol synthesis to produce meiosis-activating sterols. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 775-84. PMID 11259396 DOI: 10.1096/Fj.00-0214Com |
0.405 |
|
| 2000 |
Ruan B, Wilson WK, Pang J, Schroepfer GJ. Synthesis of [3alpha-3H]cholesta-5,8-dien-3beta-ol and tritium-labeled forms of other sterols of potential importance in the Smith-Lemli-Optiz syndrome. Steroids. 65: 29-39. PMID 10624834 DOI: 10.1016/S0039-128X(99)00079-3 |
0.388 |
|
| 1999 |
Ruan B, Wilson WK, Schroepfer GJ. An improved synthesis of (20R,22R)-cholest-5-ene-3β,20,22-triol, an intermediate in steroid hormone formation and an activator of nuclear orphan receptor LXRα Steroids. 64: 385-395. PMID 10433175 DOI: 10.1016/S0039-128X(98)00116-0 |
0.313 |
|
| 1999 |
Li S, Pang J, Wilson WK, Schroepfer GJ. Sterol synthesis. Preparation and characterization of fluorinated and deuterated analogs of oxygenated derivatives of cholesterol. Chemistry and Physics of Lipids. 99: 33-71. PMID 10377963 DOI: 10.1016/S0009-3084(99)00005-5 |
0.487 |
|
| 1999 |
Li S, Pang J, Wilson WK, Schroepfer GJ. A new approach to the stereoselective total synthesis of isotopically labeled d-ribo-phytosphingosine Tetrahedron-Asymmetry. 10: 1697-1707. DOI: 10.1016/S0957-4166(99)00161-5 |
0.334 |
|
| 1999 |
Li S, Pang J, Wilson WK, Schroepfer GJ. Efficient synthesis of deuterium‐ and tritium‐labeled d‐erythro‐sphingosine Journal of Labelled Compounds and Radiopharmaceuticals. 42: 815-826. DOI: 10.1002/(Sici)1099-1344(199909)42:9<815::Aid-Jlcr242>3.0.Co;2-2 |
0.315 |
|
| 1999 |
Su X, Wilson WK, Schroepfer GJ. Synthesis of deuterium- and tritium-labeled 25,26,26,26,27,27,27-heptafluorocholesterol Journal of Labelled Compounds and Radiopharmaceuticals. 42: 509-518. DOI: 10.1002/(Sici)1099-1344(199906)42:6<509::Aid-Jlcr211>3.0.Co;2-M |
0.339 |
|
| 1998 |
Carroll JN, Pinkerton FD, Su X, Gerst N, Wilson WK, Schroepfer GJ. Sterol synthesis, Synthesis of 3β-hydroxy-25,26,26,26,27,27,27-heptafluorocholest-5-en-7-one and its effects on HMG-CoA reductase activity in Chinese hamster ovary cells, on ACAT activity in rat jejunal microsomes, and serum cholesterol levels in rats Chemistry and Physics of Lipids. 94: 209-225. PMID 9779586 DOI: 10.1016/S0009-3084(98)00058-9 |
0.427 |
|
| 1998 |
Su X, Siddiqui A, Swaminathan S, Wilson WK, Schroepfer GJ. Preparation of 25,26,26,26,27,27,27-heptafluoro-15-ketosterols labeled at C-23 with deuterium or tritium Journal of Labelled Compounds and Radiopharmaceuticals. 41: 63-74. DOI: 10.1002/(Sici)1099-1344(199801)41:1<63::Aid-Jlcr54>3.0.Co;2-G |
0.451 |
|
| 1997 |
Siddiqui AU, Swaminathan S, Su X, Wilson WK, Schroepfer GJ. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3β-hydroxy-25,26,26,26,27,27,27-heptafluoro-5α-cholestan-15-one Chemistry and Physics of Lipids. 86: 95-119. PMID 9179993 DOI: 10.1016/S0009-3084(97)02656-X |
0.501 |
|
| 1996 |
Ruan B, Shey J, Gerst N, Wilson WK, Schroepfer GJ. Silver ion high pressure liquid chromatography provides unprecedented separation of sterols: application to the enzymatic formation of cholesta-5,8-dien-3 beta-ol. Proceedings of the National Academy of Sciences of the United States of America. 93: 11603-8. PMID 8876182 DOI: 10.1073/Pnas.93.21.11603 |
0.3 |
|
| 1995 |
Siddiqui AU, Wilson WK, Parish EJ, Gerst N, Pinkerton FD, Schroepfer GJ. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholestan-15-one and its 17 beta-epimer and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. Chemistry and Physics of Lipids. 74: 1-15. PMID 7820900 DOI: 10.1016/0009-3084(94)90106-6 |
0.348 |
|
| 1994 |
Swaminathan S, Siddiqui AU, Pinkerton FD, Gerst N, Wilson WK, Schroepfer GJ. Inhibitors of Sterol Synthesis: 3β-Hydroxy-25,26,26,26,27,27,27-heptafluoro-5α-cholestan-15-one, an Analog of a Potent Hypocholesterolemic Agent in Which Its Major Metabolism Is Blocked Biochemical and Biophysical Research Communications. 201: 168-173. PMID 8198571 DOI: 10.1006/Bbrc.1994.1684 |
0.504 |
|
| 1994 |
Siddiqui AU, Wilson WK, Schroepfer GJ. Inhibitors of sterol synthesis. An improved chemical synthesis of 26-oxygenated delta 8(14)-15-ketosterols having the 25R configuration. Chemistry and Physics of Lipids. 71: 205-218. PMID 8076403 DOI: 10.1016/0009-3084(94)90072-8 |
0.475 |
|
| 1994 |
Wilson WK, Swaminathan S, Pinkerton FD, Gerst N, Schroepfer GJ. Inhibitors of sterol synthesis. Effects of fluorine substitution at carbon atom 25 of cholesterol on its spectral and chromatographic properties and on 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in CHO-K1 cells Steroids. 59: 310-317. PMID 8073444 DOI: 10.1016/0039-128X(94)90119-8 |
0.349 |
|
| 1994 |
Siddiqui AU, Gerst N, Kim LJ, Pinkerton FD, Kisic A, Wilson WK, Schroepfer GJ. Inhibitors of sterol synthesis: effects of a 7α-alkyl analog of 3β-hydroxy-5α-cholest-8(14)-en-15-one on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells and on serum cholesterol levels and other parameters in rats Chemistry and Physics of Lipids. 70: 163-178. PMID 8033288 DOI: 10.1016/0009-3084(94)90084-1 |
0.476 |
|
| 1994 |
Siddiqui AU, Swaminathan S, Pinkerton FD, Gerst N, Wilson WK, Choi H, Schroepfer GJ. Inhibitors of sterol synthesis: synthesis and spectral properties of derivatives of 3β-hydroxy-25,26,26,26,27,27,27-heptafluoro-5α-cholest-8(14)-en-15-one fluorinated at carbon 7 or carbon 9 and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells Chemistry and Physics of Lipids. 72: 59-75. PMID 7923480 DOI: 10.1016/0009-3084(94)90017-5 |
0.49 |
|
| 1993 |
Pinkerton FD, Spilman CH, Via DP, Schroepfer GJ. Differing Effects of Three Oxysterols on Low-Density Lipoprotein Metabolism in HepG2 Cells Biochemical and Biophysical Research Communications. 193: 1091-1097. PMID 8391799 DOI: 10.1006/Bbrc.1993.1737 |
0.346 |
|
| 1993 |
Ni Y, Kim H, William K, Kisic WA, Schroepfer GJ. A revisitation of the clemmensen reduction of diosgenin. characterization of byproducts and their use in the preparation of (25R)-26-hydroxysterols. Tetrahedron Letters. 34: 3687-3690. DOI: 10.1016/S0040-4039(00)79201-X |
0.404 |
|
| 1992 |
Pinkerton FD, Pelley RP, Schroepfer GJ. Synergistic action of two oxysterols in the lowering of HMG-CoA reductase activity in CHO-K1 cells. Biochemical and Biophysical Research Communications. 186: 569-573. PMID 1632792 DOI: 10.1016/S0006-291X(05)80846-0 |
0.353 |
|
| 1992 |
Swaminathan S, Pinkerton FD, Schroepfer GJ. Inhibitors of sterol synthesis. 3 beta,25-dihydroxy-5 alpha-cholest-8(14)-en-15-one, an active metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one. Journal of Medicinal Chemistry. 35: 793-795. PMID 1542104 DOI: 10.1021/Jm00082A021 |
0.36 |
|
| 1992 |
Swaminathan S, Pinkerton FD, Wilson WK, Schroepfer GJ. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of (25R)-5α-cholest-8(14)-ene-3β,15β,26-triol, a potential metabolite of 3β-hydroxy-5α-cholest-8(14)-en-15-one and its effects on 3-hydroxy-3-methylglutaryl-coenzyme A reductase in CHO-K1 cells Chemistry and Physics of Lipids. 61: 235-242. PMID 1525963 DOI: 10.1016/0009-3084(92)90103-V |
0.485 |
|
| 1992 |
Siddiqui AU, Wilson WK, Ruecker KE, Pinkerton FD, Schroepfer GJ. Inhibitors of sterol synthesis. Chemical syntheses and spectral properties of 26-oxygenated derivatives of 3β-hydroxy-5α-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells Chemistry and Physics of Lipids. 63: 77-90. PMID 1486662 DOI: 10.1016/0009-3084(92)90025-K |
0.492 |
|
| 1992 |
Siddiqui AU, Wilson WK, Swaminathan S, Schroepfer GJ. Efficient preparation of steroidal 5,7-dienes of high purity Chemistry and Physics of Lipids. 63: 115-129. PMID 1486654 DOI: 10.1016/0009-3084(92)90028-N |
0.45 |
|
| 1992 |
Kim HS, Wilson WK, Kirkpatrick ND, Pinkerton FD, Swaminathan S, Hylarides MD, Schroepfer GJ. Inhibitors of sterol synthesis. Chemical synthesis of 7 alpha-ethyl and 16 alpha-ethyl derivatives of delta 8(14)-15-oxygenated sterols and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase in CHO-K1 cells. Chemistry and Physics of Lipids. 62: 55-67. PMID 1423803 DOI: 10.1016/0009-3084(92)90054-S |
0.39 |
|
| 1991 |
Herz JE, Wilson WK, Pinkerton FD, Schroepfer GJ. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3β-hydroxy-24-dimethylamino-5α-chol-8(14)-en-15-one and its effects on HMG-CoA reductase activity in CHO-K1 cells Chemistry and Physics of Lipids. 60: 61-69. PMID 1813179 DOI: 10.1016/0009-3084(91)90015-4 |
0.493 |
|
| 1991 |
Herz JE, Swaminathan S, Wilson WK, Schroepfer GJ. Inhibitors of sterol synthesis. An efficient and specific side chain oxidation of 3β-hydroxy-5α-cholest-8(14)-en-15-one. Facile access to its metabolites and analogs. Tetrahedron Letters. 32: 3923-3926. DOI: 10.1016/0040-4039(91)80590-3 |
0.501 |
|
| 1989 |
Stephens TW, Schroepfer GJ. Inhibitors of sterol synthesis. 15-Oxygenated steryl ester hydrolase activity of rat liver at neutral and acid pH Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1001: 127-133. PMID 2917137 DOI: 10.1016/0005-2760(89)90138-0 |
0.329 |
|
| 1989 |
Pajewski TN, Brabson JS, Kisic A, Wang KS, Hylarides MD, Jackson EM, Schroepfer GJ. Inhibitors of sterol synthesis. Metabolism of [2,4-3H]5 alpha-cholest-8(14)-en-3 beta-ol-15-one after oral administration to a nonhuman primate. Chemistry and Physics of Lipids. 49: 243-63. PMID 2720860 DOI: 10.1016/0009-3084(89)90072-8 |
0.403 |
|
| 1989 |
Emmons GT, Wilson WK, Schroepfer GJ. 1H and 13C NMR assignments for lanostan‐3β‐ol derivatives: Revised assignments for lanosterol Magnetic Resonance in Chemistry. 27: 1012-1024. DOI: 10.1002/Mrc.1260271103 |
0.473 |
|
| 1988 |
Monger DJ, Schroepfer GJ. Inhibitors of cholesterol biosynthesis. Further studies of the metabolism of 5α-cholest-8(14)-en-3β-ol-15-one in rat liver preparations Chemistry and Physics of Lipids. 47: 21-46. PMID 3396133 DOI: 10.1016/0009-3084(88)90030-8 |
0.497 |
|
| 1988 |
Brabson JS, Schroepfer GJ. Inhibitors of sterol synthesis. The effects of dietary 5α-cholest-8(14)-en-3β-ol-15-one on the fate of [4-14C]cholesterol and [2,4-3H]5α-cholest-8(14)-en-3β-ol-15-one after intragastric administration to rats Chemistry and Physics of Lipids. 47: 1-20. PMID 3396132 DOI: 10.1016/0009-3084(88)90029-1 |
0.456 |
|
| 1988 |
Bowen ST, Parish EJ, Wilson WK, Schroepfer GJ, Quiocho FA. Inhibitors of sterol synthesis. Concerning the structure of 15β-methyl-5α,14β-cholest-7-ene-3β,15α-diol, an inhibitor of cholesterol biosynthesis Chemistry and Physics of Lipids. 46: 245-251. PMID 3365828 DOI: 10.1016/0009-3084(88)90038-2 |
0.456 |
|
| 1988 |
Schroepfer GJ, Kim HS, Vermilion JL, Stephens TW, Pinkerton FD, Needleman DH, Wilson WK, Pyrek JS. Enzymatic formation and chemical synthesis of an active metabolite of 3β-hydroxy-5α-cholest-8(14)-en-15-one, a potent regulator of cholesterol metabolism Biochemical and Biophysical Research Communications. 151: 130-136. PMID 3348769 DOI: 10.1016/0006-291X(88)90568-2 |
0.497 |
|
| 1988 |
Schroepfer GJ, Parish EJ, Kandutsch AA. Inhibitors of sterol biosynthesis. Synthesis and activities of ring C oxygenated sterols. Chemistry and Physics of Lipids. 46: 147-54. PMID 3342458 DOI: 10.1016/0009-3084(88)90125-9 |
0.383 |
|
| 1988 |
Brabson JS, Schroepfer GJ. Inhibitors of sterol synthesis. Studies of the distribution and metabolism of 5α-[2,4−3H] cholest-8(14)-en-3β-ol-15-one after intragastric administration to rats Steroids. 52: 51-68. PMID 3247671 DOI: 10.1016/0039-128X(88)90217-6 |
0.438 |
|
| 1988 |
Wilson WK, Wang K, Kisic A, Schroepfer GJ. Concerning the chemical synthesis of 3β-hydroxy-5α-cholest-8(14)-en-15-one, a novel regulator of cholesterol metabolism Chemistry and Physics of Lipids. 48: 7-17. PMID 3208416 DOI: 10.1016/0009-3084(88)90129-6 |
0.499 |
|
| 1988 |
Schroepfer GJ, Christophe A, Chu AJ, Izumi A, Kisic A, Sherrill BC. Inhibitors of sterol synthesis. A major role of chylomicrons in the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in the rat. Chemistry and Physics of Lipids. 48: 29-58. PMID 3208415 DOI: 10.1016/0009-3084(88)90131-4 |
0.35 |
|
| 1988 |
Stephens TW, Schroepfer GJ. Inhibitors of sterol synthesis. Oleate ester of 5α-cholest-8(14)-en-3β-ol-15-one as a substrate for pancreatic cholesterol esterase Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 963: 395-400. PMID 3196743 DOI: 10.1016/0005-2760(88)90307-4 |
0.33 |
|
| 1988 |
Pinkerton FD, Izumi A, Schroepfer GJ. Inhibitors of sterol synthesis. 14α-ethyl-5α-cholest-7-ene-3β,15α-diol induces changes in the sterol composition and the morphology of CHO-K1 cells Biochemical and Biophysical Research Communications. 157: 359-363. PMID 3196343 DOI: 10.1016/S0006-291X(88)80055-X |
0.427 |
|
| 1988 |
Wilson DK, Wilson WK, Quiocho FA, Schroepfer GJ. Crystal structure of 3β-benzoyloxy-6α-chloro-5α-cholest-7-ene, a key intermediate in the chemical synthesis of 5α-cholest-8(14)-en-3β-ol-15-one Chemistry and Physics of Lipids. 47: 283-289. PMID 3191560 DOI: 10.1016/0009-3084(88)90051-5 |
0.472 |
|
| 1988 |
Wilson DK, Wilson WK, Quiocho FA, Schroepfer GJ. Concerning the structure of 3β-benzoyloxy-5β-cholesta-8,14-diene, a major byproduct in the chemical synthesis of 5α-cholest-8(14)-en-3β-ol-15-one Chemistry and Physics of Lipids. 47: 273-282. PMID 3191559 DOI: 10.1016/0009-3084(88)90050-3 |
0.402 |
|
| 1988 |
Pinkerton FD, Kirkpatrick ND, Schroepfer GJ. Inhibitors of sterol synthesis. Exogenous oleate reduces the inhibitory effect of 5α-Cholest-8(14)-en-3β-ol-15-one on the growth of CHO-K1 cells Biochemical and Biophysical Research Communications. 156: 689-694. PMID 3190675 DOI: 10.1016/S0006-291X(88)80897-0 |
0.355 |
|
| 1988 |
Schroepfer GJ, Parish EJ, Tsuda M, Kandutsch AA. Inhibitors of sterol synthesis. Chemical syntheses, properties and effects of 4,4-dimethyl-15-oxygenated sterols on sterol synthesis and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells. Chemistry and Physics of Lipids. 47: 187-207. PMID 3168085 DOI: 10.1016/0009-3084(88)90012-6 |
0.357 |
|
| 1988 |
Pajewski TN, Pinkerton FD, Miller LR, Schroepfer GJ. Inhibitors of sterol synthesis. Studies of the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in Chinese hamster ovary cells and its effects on activities of early enzymes in cholesterol biosynthesis. Chemistry and Physics of Lipids. 48: 153-68. PMID 2907421 DOI: 10.1016/0009-3084(88)90086-2 |
0.411 |
|
| 1988 |
Miller LR, Raulston DL, Schroepfer GJ. Inhibitors of sterol synthesis. Effects of dietary 5 alpha-cholest-8(14)-en-3 beta-ol-15-one on early enzymes in hepatic cholesterol biosynthesis. Chemistry and Physics of Lipids. 47: 177-86. PMID 2901919 DOI: 10.1016/0009-3084(88)90011-4 |
0.389 |
|
| 1987 |
Miller LR, Needleman DH, Brabson JS, Wang KS, Schroepfer GJ. 5 alpha-cholest-8(14)-en-3 beta-ol-15-one. A competitive substrate for acyl coenzyme A:cholesterol acyl transferase. Biochemical and Biophysical Research Communications. 148: 934-40. PMID 3689404 DOI: 10.1016/S0006-291X(87)80222-X |
0.449 |
|
| 1987 |
Needleman DH, Strong K, Stemke KA, Brabson JS, Kisic A, Schroepfer GJ. Inhibitors of sterol synthesis. Effect of dietary 5α-cholest-8(14)-EN-3β-OL-15-one on acat activity of jejunal microsomes of the rat Biochemical and Biophysical Research Communications. 148: 920-925. PMID 3689403 DOI: 10.1016/S0006-291X(87)80220-6 |
0.447 |
|
| 1987 |
Schroepfer GJ, Pajewski TN, Hylarides M, Kisic A. 5α-Cholest-8(14)-en-3β-ol-15-one. In vivo conversion to cholesterol upon oral administration to a nonhuman primate Biochemical and Biophysical Research Communications. 146: 1027-1032. PMID 3619912 DOI: 10.1016/0006-291X(87)90750-9 |
0.332 |
|
| 1987 |
Schroepfer GJ, Christophe A, Needleman DH, Kisic A, Sherrill BC. Inhibitors of sterol synthesis. Dietary administration of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one inhibits the intestinal absorption of cholesterol in lymph-cannulated rats. Biochemical and Biophysical Research Communications. 146: 1003-8. PMID 3619910 DOI: 10.1016/0006-291X(87)90747-9 |
0.424 |
|
| 1986 |
Fliesler SJ, Schroepfer GJ. In vitro metabolism of mevalonic acid in the bovine retina. Journal of Neurochemistry. 46: 448-460. PMID 3941316 DOI: 10.1111/J.1471-4159.1986.Tb12989.X |
0.322 |
|
| 1984 |
Schroepfer GJ, Sherrill BC, Wang K, Wilson WK, Kisic A, Clarkson TB. 5 alpha-Cholest-8(14)-en-3 beta-ol-15-one lowers serum cholesterol and induces profound changes in the levels of lipoprotein cholesterol and apoproteins in monkeys fed a diet of moderate cholesterol content Proceedings of the National Academy of Sciences of the United States of America. 81: 6861-6865. PMID 6593730 DOI: 10.1073/Pnas.81.21.6861 |
0.331 |
|
| 1982 |
Fliesler SJ, Schroepfer GJ. Sterol composition of bovine retinal rod outer segment membranes and whole retinas Biochimica Et Biophysica Acta. 711: 138-148. PMID 7066367 DOI: 10.1016/0005-2760(82)90020-0 |
0.333 |
|
| 1982 |
Schroepfer GJ, Parish EJ, Kisic A, Jackson EM, Farley CM, Mott GE. 5 alpha-Cholest-8(14)-en-3 beta-ol-15-one, a potent inhibitor of sterol biosynthesis, lowers serum cholesterol and alters distributions of cholesterol in lipoproteins in baboons. Proceedings of the National Academy of Sciences of the United States of America. 79: 3042-6. PMID 6953447 DOI: 10.1073/Pnas.79.9.3042 |
0.34 |
|
| 1981 |
Schroepfer GJ, Parish EJ, Kisic A, Frome DM, Kandutsch AA. Inhibitors of sterol synthesis. Chemical syntheses and activities of new derivatives of 15-oxygenated sterols Chemistry and Physics of Lipids. 29: 201-211. DOI: 10.1016/0009-3084(81)90051-7 |
0.493 |
|
| 1981 |
Parish EJ, Schroepfer GJ. Inhibitors of sterol synthesis. Synthesis of [2,4-3H]5α-cholest-8(14)-ene-3β,7α,15α-triol and [2,4-3H]5α-cholest-8(14)-en-38-ol-15-one Journal of Labelled Compounds and Radiopharmaceuticals. 18: 1429-1436. DOI: 10.1002/Jlcr.2580181006 |
0.464 |
|
| 1980 |
Pascal RA, Schroepfer GJ. Enzymatic isomerization (delta 7 to delta 8) of the nuclear double bond of 14 alpha-alkyl substituted sterol precursors of cholesterol. Biochemical and Biophysical Research Communications. 94: 932-9. PMID 7396942 DOI: 10.1016/0006-291X(80)91324-8 |
0.483 |
|
| 1980 |
Schroepfer GJ, Walker V, Parish EJ, Kisic A. Inhibitors of sterol synthesis. Hypocholesterolemic action of dietary 9 alpha-fluoro-5 alpha-cholest-8(14)-en-3 beta-ol-15-one. Biochemical and Biophysical Research Communications. 93: 813-8. PMID 7387678 DOI: 10.1016/0006-291X(80)91149-3 |
0.4 |
|
| 1980 |
Schroepfer GJ, Pascal RA, Kandutsch AA. Inhibition of sterol biosynthesis by 14 alpha-hydroxy-delta 7-sterols. Experientia. 36: 518. PMID 7379935 DOI: 10.1007/Bf01965773 |
0.353 |
|
| 1980 |
Schroepfer GJ, Parish EJ, Kandutsch AA. Further studies on the inhibition of sterol biosynthesis in animal cells by 15-oxygenated sterols. Chemistry and Physics of Lipids. 25: 265-85. PMID 535100 DOI: 10.1016/0009-3084(79)90111-7 |
0.338 |
|
| 1980 |
Schroepfer GJ, Parish EJ, Tsuda M, Kandutsch AA. Inhibition of sterol biosynthesis by 9 alpha-fluoro and 9 alpha-hydroxy derivatives of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one. Biochemical and Biophysical Research Communications. 91: 606-13. PMID 518657 DOI: 10.1016/0006-291X(79)91565-1 |
0.522 |
|
| 1980 |
Parish EJ, Schroepfer GJ. Inhibitors of sterol biosynthesis. Synthesis of 9.alpha.-fluoro-3.beta.-hydroxy-5.alpha.-cholest-8(14)-en-15-one and related compounds The Journal of Organic Chemistry. 45: 4034-4037. DOI: 10.1021/Jo01308A018 |
0.362 |
|
| 1980 |
Pascal RA, Chang P, Schroepfer GJ. Possible mechanisms of demethylation of 14.alpha.-methyl sterols in cholesterol biosynthesis Journal of the American Chemical Society. 102: 6599-6601. DOI: 10.1021/Ja00541A055 |
0.35 |
|
| 1980 |
Parish E, Schroepfer G. Selective oxidation of steroidal allylic alcohols Chemistry and Physics of Lipids. 27: 281-288. DOI: 10.1016/0009-3084(80)90023-7 |
0.451 |
|
| 1980 |
Parish EJ, Schroepfer GJ. Stereoselectivity of raney nickel catalyst in hydrogenolysis of a steroidal α,β-unsaturated epoxide. Chemical synthesis of 3β-benzoyloxy-5α-cholest-8(14)-en-15α-ol Chemistry and Physics of Lipids. 26: 141-147. DOI: 10.1016/0009-3084(80)90003-1 |
0.453 |
|
| 1979 |
Parish EJ, Tsuda M, Schroepfer GJ. Synthesis, properties and reactions of 3 beta-benzoyloxy-7 alpha-15 beta-dichloro-5 alpha-cholest-8(14)-ene. Chemistry and Physics of Lipids. 24: 167-82. PMID 455568 DOI: 10.1016/0009-3084(79)90086-0 |
0.363 |
|
| 1979 |
Schroepfer GJ, Pascal RA, Kandutsch AA. Inhibition of sterol synthesis in animal cells by 15-oxygenated sterols with the unnatural cis-C-D ring junction-"5alpha,14beta-cholest-7-en-15alpha-ol-3-one and 5alpha,14beta-cholest-7-en-15beta-ol-3-one. Biochemical Pharmacology. 28: 249-52. PMID 426840 DOI: 10.1016/0006-2952(79)90511-2 |
0.512 |
|
| 1979 |
Tsuda M, Parish EJ, Schroepfer GJ. Carbon-13 nuclear magnetic resonance studies of allylic hydroxysterols. Assignment of structure of 5.alpha.-cholest-8(14)-ene-3.beta.,7.alpha.,15.alpha.-triol, an inhibitor of sterol synthesis The Journal of Organic Chemistry. 44: 1282-1289. DOI: 10.1021/Jo01322A021 |
0.344 |
|
| 1979 |
Parish EJ, Schroepfer GJ. Chemical syntheses of 5α-cholesta-6,8(14)-dien-3β-ol-15-one and related 15-oxygenated sterols Chemistry and Physics of Lipids. 25: 381-394. DOI: 10.1016/0009-3084(79)90076-8 |
0.46 |
|
| 1979 |
Parish EJ, Tsuda M, Schroepfer GJ. Synthesis, properties and reactions of 3β-benzoyloxy-7α,15β-dichloro-5α-cholest-8(14)-ene Chemistry and Physics of Lipids. 25: i-ii. DOI: 10.1016/0009-3084(79)90071-9 |
0.449 |
|
| 1979 |
Parish EJ, Tsuda M, Schroepfer GJ. Synthesis and spectral properties of 5α-cholesta-6,8,14-trien-3β-ol Chemistry and Physics of Lipids. 25: 111-124. DOI: 10.1016/0009-3084(79)90061-6 |
0.482 |
|
| 1979 |
Parish EJ, Tsuda M, Schroepfer GJ. Inhibitors of sterol biosynthesis. Syntheses of 14α-alkyl substituted 15-oxygenated sterols Chemistry and Physics of Lipids. 24: 209-236. DOI: 10.1016/0009-3084(79)90028-8 |
0.449 |
|
| 1978 |
Schroepfer GJ, Parish EJ, Gilliland GL, Newcomer ME, Sommerville LL, Quiocho FA, Kandutsch AA. 7alpha, 15beta-Dichloro-5alpha-cholest-8 (14)-en-3beta-ol, a novel inhibitor of sterol biosynthesis in animal cells. Biochemical and Biophysical Research Communications. 84: 823-9. PMID 718720 DOI: 10.1016/0006-291X(78)90778-7 |
0.507 |
|
| 1978 |
Schroepfer GJ, Pascal RA, Shaw R, Kandutsch AA. Inhibition of sterol biosynthesis by 14alpha-hydroxymethyl sterols. Biochemical and Biophysical Research Communications. 83: 1024-31. PMID 708421 DOI: 10.1016/0006-291X(78)91498-5 |
0.467 |
|
| 1978 |
Spike TE, Martin JA, Huntoon S, Wang AH, Knapp FF, Schroepfer GJ. Sterol synthesis. Chemical synthesis, structure determination and metabolism of 14 alpha-methyl-5 alpha-cholest-7-en-3 beta, 15 beta-diol and 14 alpha-methyl-5 alpha-cholest-7-en-3 beta, 15 alpha-diol. Chemistry and Physics of Lipids. 21: 31-58. PMID 668029 DOI: 10.1016/0009-3084(78)90053-1 |
0.348 |
|
| 1977 |
Schroepfer GJ, Monger D, Taylor AS, Chamberlain JS, Parish EJ, Kisic A, Kandutsch AA. Inhibitors of sterol synthesis. Hypocholesterolemic action of dietary 5alpha-cholest-8(14)-en-3beta-ol-15-one in rats and mice. Biochemical and Biophysical Research Communications. 78: 1227-33. PMID 921774 DOI: 10.1016/0006-291X(77)91424-3 |
0.359 |
|
| 1977 |
Schroepfer GJ, Parish EJ, Kandutsch AA. 14alpha-ethyl-5alpha-cholest-7-ene-3beta,15alpha-diol, an extraodinarily potent inhibitor of sterol biosynthesis in animal cells. Journal of the American Chemical Society. 99: 5494-5496. PMID 886111 DOI: 10.1021/Ja00458A051 |
0.338 |
|
| 1977 |
Parish EJ, Schroepfer GJ. Sterol synthesis. Syntheses of 15-oxygenated 5alpha, 14beta-cholest-7-en-3beta-ol derivatives. Chemistry and Physics of Lipids. 19: 107-13. PMID 880727 DOI: 10.1016/0009-3084(77)90091-3 |
0.346 |
|
| 1977 |
Conner BN, Parish EJ, Schroepfer GJ, Quiocho FA. Synthesis and crystal structure of 3β-p-bromobenzoyloxy-14α, 15α-epoxy-5α-cholest-7-ene Chemistry and Physics of Lipids. 18: 240-257. PMID 870214 DOI: 10.1016/0009-3084(77)90012-3 |
0.402 |
|
| 1977 |
Parish EJ, Spike TE, Schroepfer GJ. Sterol synthesis. Chemical synthesis of 3beta-benzoyloxy -14alpha, 15alpha-epoxy-5alpha-cholest-7-ene, a key intermediate in the synthesis of 15-oxygenated sterols. Chemistry and Physics of Lipids. 18: 233-9. PMID 870213 DOI: 10.1016/0009-3084(77)90011-1 |
0.35 |
|
| 1977 |
Parish EJ, Schroepfer GJ. Sterol synthesis. A novel reductive rearrangement of an alpha,beta-unsaturated steroidal epoxide; a new chemical synthesis of 5alpha-cholest-8(14)-en-3beta, 15alpha-diol. Chemistry and Physics of Lipids. 18: 258-66. PMID 858170 DOI: 10.1016/0009-3084(77)90013-5 |
0.35 |
|
| 1977 |
Schroepfer GJ, Raulston DL, Kandutsch AA. Inhibition of sterol synthesis in L cells by 14α-ethyl-5α-cholest-7-en-15α-ol-3-one at nanomolar concentrations Biochemical and Biophysical Research Communications. 79: 406-410. PMID 588274 DOI: 10.1016/0006-291X(77)90172-3 |
0.458 |
|
| 1976 |
Knapp FF, Wilson MS, Schroepfer GJ. Mass spectral fragmentation of 5α-hydroxysteroids Chemistry and Physics of Lipids. 16: 31-59. PMID 1260960 DOI: 10.1016/0009-3084(76)90013-X |
0.443 |
|
| 1976 |
Knapp FF, Schroepfer GJ. Mass spectrometry of sterols. Electron ionization induced fragmentation of C-4-alkylated cholesterols. Chemistry and Physics of Lipids. 17: 466-500. PMID 991394 DOI: 10.1016/0009-3084(76)90048-7 |
0.313 |
|
| 1976 |
Raulston DL, Mishaw CO, Parish EJ, Schroepfer GJ. Inhibition of hepatic sterol synthesis and reduction of serum cholesterol in rats by 5alpha-cholest-8(14)-en-3beta-ol-15-one. Biochemical and Biophysical Research Communications. 71: 98409. PMID 971324 DOI: 10.1016/0006-291X(76)90751-8 |
0.446 |
|
| 1976 |
Phillips GN, Quiocho FA, Sass RL, Werness P, Emery H, Knapp FF, Schroepfer GJ. Sterol biosynthesis: Establishment of the structure of 3β-p-bromobenzoyloxy-5α-cholest-8(14)-en-15β-ol Bioorganic Chemistry. 5: 1-10. DOI: 10.1016/0045-2068(76)90011-0 |
0.46 |
|
| 1976 |
Parish EJ, Newcomer ME, Gilliland GL, Quiocho FA, Schroepfer GJ. Synthesis and structure of 15-oxygenated 5α,14β-cholest-7-en-3β-ol derivatives Tetrahedron Letters. 17: 4401-4404. DOI: 10.1016/0040-4039(76)80127-X |
0.445 |
|
| 1975 |
Knapp FF, Schroepfer GJ. Chemical synthesis, spectral properties, and chromatography of 4α-methyl and 4β-methyl isomers of (24R)-24-ethyl-5α-cholestan-3β-ol and (24S)-24-ethyl-cholesta-5,22-dien-3β-ol Steroids. 26: 339-357. PMID 1198622 DOI: 10.1016/0039-128X(75)90079-3 |
0.462 |
|
| 1975 |
Knapp FF, Trowbridge ST, Schroepfer GJ. Letter: Concerning the role of 4beta-methyl sterols in cholesterol biosynthesis. Journal of the American Chemical Society. 97: 3522-3524. PMID 1141583 DOI: 10.1021/Ja00845A044 |
0.317 |
|
| 1974 |
Knapp FF, Schroepfer GJ. A novel synthesis of 4 alpha- and 4 beta-methycholest-5-en-3 beta-ol from 6 beta-bromo-4-methylcholest-4-en-3-one. Journal of Organic Chemistry. 39: 3247-3250. PMID 4425319 DOI: 10.1021/Jo00936A016 |
0.311 |
|
| 1974 |
Knapp FF, Schroepfer GJ. An unusual mass spectral fragmentation of C-4 alkylated cholesterols Journal of the Chemical Society, Chemical Communications. DOI: 10.1039/C3974000537B |
0.387 |
|
| 1974 |
Spike TE, Wang AHJ, Paul IC, Schroepfer GJ. Structure of a potential intermediate in cholesterol biosynthesis Journal of the Chemical Society, Chemical Communications. 477-478. DOI: 10.1039/C39740000477 |
0.491 |
|
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