Mark E. Gelsthorpe, Ph.D. - Related publications

Affiliations: 
2005 Saint Louis University, St. Louis, MO, United States 
Area:
Genetics, Molecular Biology, Cell Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Wu KZL, Jones RA, Tachie-Menson T, Macartney TJ, Wood NT, Varghese J, Gourlay R, Soares RF, Smith JC, Sapkota GP. Pathogenic palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling. Wellcome Open Research. 4: 133. PMID 31656861 DOI: 10.12688/wellcomeopenres.15403.1   
2019 Chien J, Wolf FW, Grosche S, Yosef N, Garriga G, Mörck C. The Enigmatic Canal-Associated Neurons Regulate Larval Development Through a cAMP Signalling Pathway. Genetics. PMID 31619445 DOI: 10.1534/genetics.119.302628   
2019 Kang KH, Han JE, Hong YB, Nam SH, Choi BO, Koh H. Human HSPB1 mutation recapitulates features of distal hereditary motor neuropathy (dHMN) in Drosophila. Biochemical and Biophysical Research Communications. PMID 31630804 DOI: 10.1016/j.bbrc.2019.10.110   
2019 Cox RL, Hofley CM, Tatapudy P, Patel RK, Dayani Y, Betcher M, LaRocque JR. Functional conservation of RecQ helicase BLM between humans and Drosophila melanogaster. Scientific Reports. 9: 17527. PMID 31772289 DOI: 10.1038/s41598-019-54101-5   
2019 Zhao Y, Huang G, Zhang W. Mutations in NlInR1 affect normal growth and lifespan in the brown planthopper Nilaparvata lugens. Insect Biochemistry and Molecular Biology. 103246. PMID 31618682 DOI: 10.1016/j.ibmb.2019.103246   
2019 Link N, Chung H, Jolly A, Withers M, Tepe B, Arenkiel BR, Shah PS, Krogan NJ, Aydin H, Geckinli BB, Tos T, Isikay S, Tuysuz B, Mochida GH, Thomas AX, et al. Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly. Developmental Cell. PMID 31735666 DOI: 10.1016/j.devcel.2019.10.009   
2019 Horn M, Mitesser O, Hovestadt T, Yoshii T, Rieger D, Helfrich-Förster C. The Circadian Clock Improves Fitness in the Fruit Fly, . Frontiers in Physiology. 10: 1374. PMID 31736790 DOI: 10.3389/fphys.2019.01374   
2019 Klein SD, Nguyen DC, Bhakta V, Wong D, Chang VY, Davidson TB, Martinez-Agosto JA. Mutations in the sonic hedgehog pathway cause macrocephaly-associated conditions due to crosstalk to the PI3K/AKT/mTOR pathway. American Journal of Medical Genetics. Part A. PMID 31639285 DOI: 10.1002/ajmg.a.61368   
2019 Yang X, Bayat V, DiDonato N, Zhao Y, Zarnegar B, Siprashvili Z, Lopez-Pajares V, Sun T, Tao S, Li C, Rump A, Khavari P, Lu B. Genetic and genomic studies of pathogenic EXOSC2 mutations in the newly described disease SHRF implicate the autophagy pathway in disease pathogenesis. Human Molecular Genetics. PMID 31628467 DOI: 10.1093/hmg/ddz251   
2019 Suzuki H, Yoshida T, Morisada N, Uehara T, Kosaki K, Sato K, Matsubara K, Takano-Shimizu T, Takenouchi T. De novo NSF mutations cause early infantile epileptic encephalopathy. Annals of Clinical and Translational Neurology. PMID 31675180 DOI: 10.1002/acn3.50917   
2019 Kim M, Du OY, Whitney RJ, Wilk R, Hu J, Krause HM, Kavaler J, Reed BH. A Functional Analysis of the Drosophila Gene : Evidence for Positive Regulation of EGFR Signaling. G3 (Bethesda, Md.). PMID 31649045 DOI: 10.1534/g3.119.400829   
2019 Wang SH, Elgin SCR. The impact of genetic background and cell lineage on the level and pattern of gene expression in position effect variegation. Epigenetics & Chromatin. 12: 70. PMID 31722719 DOI: 10.1186/s13072-019-0314-5   
2019 DiStasio A, Paulding D, Chaturvedi P, Stottmann RW. Nubp2 is required for cranial neural crest survival in the mouse. Developmental Biology. PMID 31733190 DOI: 10.1016/j.ydbio.2019.10.039   
2019 Leviczky T, Molnár E, Papdi C, Őszi E, Horváth GV, Vizler C, Nagy V, Pauk J, Bögre L, Magyar Z. E2FA and E2FB transcription factors coordinate cell proliferation with seed maturation. Development (Cambridge, England). PMID 31666236 DOI: 10.1242/dev.179333   
2019 Wang J, Rousseau J, Kim E, Ehresmann S, Cheng YT, Duraine L, Zuo Z, Park YJ, Li-Kroeger D, Bi W, Wong LJ, Rosenfeld J, Gleeson J, Faqeih E, Alkuraya FS, et al. Loss of Oxidation Resistance 1, OXR1, Is Associated with an Autosomal-Recessive Neurological Disease with Cerebellar Atrophy and Lysosomal Dysfunction. American Journal of Human Genetics. PMID 31785787 DOI: 10.1016/j.ajhg.2019.11.002   
2019 Holdener BC, Percival CJ, Grady RC, Cameron DC, Berardinelli SJ, Zhang A, Neupane S, Takeuchi M, Jimenez-Vega JC, Uddin SMZ, Komatsu DE, Honkanen R, Dubail J, Apte SS, Sato T, et al. ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in a mouse model of Peters Plus Syndrome. Human Molecular Genetics. PMID 31600785 DOI: 10.1093/hmg/ddz225   
2019 Domingos PM, Jenny A, Combie KF, Del Alamo D, Mlodzik M, Steller H, Mollereau B. Regulation of Numb during planar cell polarity establishment in the Drosophila eye. Mechanisms of Development. 103583. PMID 31678471 DOI: 10.1016/j.mod.2019.103583   
2019 Hatkevich T, Boudreau V, Rubin T, Maddox PS, Huynh JR, Sekelsky J. Centromeric SMC1 promotes centromer clustering and stabilizes meiotic homolog pairing. Plos Genetics. 15: e1008412. PMID 31609962 DOI: 10.1371/journal.pgen.1008412   
2019 Li N, Oakes JA, Storbeck K, Cunliffe VT, Krone N. The P450 side chain cleavage enzyme Cyp11a2 facilitates steroidogenesis in zebrafish. The Journal of Endocrinology. PMID 31693487 DOI: 10.1530/JOE-19-0384   
2019 Li T, Kang X, Wei L, Zhang D, Lin H. A gain-of-function mutation in Brassinosteroid-insensitive 2 alters Arabidopsis floral organ development by altering auxin levels. Plant Cell Reports. PMID 31820142 DOI: 10.1007/s00299-019-02489-9   
2019 Vásquez-Procopio J, Osorio B, Cortés-Martínez L, Hernández-Hernández F, Medina-Contreras O, Ríos-Castro E, Comjean A, Li F, Hu Y, Mohr S, Perrimon N, Missirlis F. Intestinal response to dietary manganese depletion in Drosophila. Metallomics : Integrated Biometal Science. PMID 31799578 DOI: 10.1039/c9mt00218a   
2019 Finegan TM, Hervieux N, Nestor-Bergmann A, Fletcher AG, Blanchard GB, Sanson B. The tricellular vertex-specific adhesion molecule Sidekick facilitates polarised cell intercalation during Drosophila axis extension. Plos Biology. 17: e3000522. PMID 31805038 DOI: 10.1371/journal.pbio.3000522   
2019 Xu T, Jiang X, Denton D, Kumar S. Ecdysone controlled cell and tissue deletion. Cell Death and Differentiation. PMID 31745213 DOI: 10.1038/s41418-019-0456-9   
2019 Guo H, Bettella E, Marcogliese PC, Zhao R, Andrews JC, Nowakowski TJ, Gillentine MA, Hoekzema K, Wang T, Wu H, Jangam S, Liu C, Ni H, Willemsen MH, van Bon BW, ... , et al. Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders. Nature Communications. 10: 4679. PMID 31616000 DOI: 10.1038/s41467-019-12435-8   
2019 Young RM, Ewan KB, Ferrer VP, Allende ML, Godovac-Zimmermann J, Dale TC, Wilson SW. Developmentally regulated splice variants mediate transcriptional repressor functions during eye formation. Elife. 8. PMID 31829936 DOI: 10.7554/eLife.51447   
2019 Gao Y, Zhang X, Xiao L, Zhai C, Yi T, Wang G, Wang E, Ji X, Hu L, Shen G, Wu S. Usp10 Modulates the Hippo Pathway by Deubiquitinating and Stabilizing the Transcriptional Coactivator Yorkie. International Journal of Molecular Sciences. 20. PMID 31795326 DOI: 10.3390/ijms20236013   
2019 Capasso TL, Li B, Volek HJ, Khalid W, Rochon ER, Anbalagan A, Herdman C, Yost HJ, Villanueva FS, Kim K, Roman BL. BMP10-mediated ALK1 signaling is continuously required for vascular development and maintenance. Angiogenesis. PMID 31828546 DOI: 10.1007/s10456-019-09701-0   
2019 Dai C, Chen Y, Hu L, Du J, Gong F, Dai J, Zhang S, Wang M, Chen J, Guo J, Zheng W, Lu C, Wu Y, Lu G, Lin G. ZP1 mutations are associated with empty follicle syndrome: evidence for the existence of an intact oocyte and a zona pellucida in follicles up to the early antral stage. A case report. Human Reproduction (Oxford, England). PMID 31734689 DOI: 10.1093/humrep/dez174   
2019 Fischer B, Ly TD, Schmidt V, Hendig D, Kuhn J, Knabbe C, Faust I. Xylosyltransferase-deficient human HEK293 cells show a strongly reduced proliferation capacity and viability. Biochemical and Biophysical Research Communications. PMID 31677793 DOI: 10.1016/j.bbrc.2019.10.148   
2019 Lim J, Choe CP. Functional analysis of engrailed in Tribolium segmentation. Mechanisms of Development. 103594. PMID 31778794 DOI: 10.1016/j.mod.2019.103594   
2019 Yao D, Gonzales-Vigil E, Mansfield SD. Arabidopsis sucrose synthase localization indicates a primary role in sucrose translocation in phloem. Journal of Experimental Botany. PMID 31805187 DOI: 10.1093/jxb/erz539   
2019 Borreguero-Muñoz N, Fletcher GC, Aguilar-Aragon M, Elbediwy A, Vincent-Mistiaen ZI, Thompson BJ. The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth. Plos Biology. 17: e3000509. PMID 31613895 DOI: 10.1371/journal.pbio.3000509   
2019 Bongiovanni A, Liverani C, Recine F, Mercatali L, Severi S, Ibrahim T. Comment on paper by Lemelin et al.: Elderly patients with metastatic neuroendocrine tumors are undertreated and have shorter survival: The LyREMeNET study. Neuroendocrinology. PMID 31689704 DOI: 10.1159/000504550   
2019 Shimizu T, Kacprzak SM, Mochizuki N, Nagatani A, Watanabe S, Shimada T, Tanaka K, Hayashi Y, Arai M, Leister D, Okamoto H, Terry MJ, Masuda T. The retrograde signaling protein GUN1 regulates tetrapyrrole biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31732672 DOI: 10.1073/pnas.1911251116   
2019 Liu MN, Zhang K, Xu TM. The role of BMP15 and GDF9 in the pathogenesis of primary ovarian insufficiency. Human Fertility (Cambridge, England). 1-8. PMID 31607184 DOI: 10.1080/14647273.2019.1672107   
2019 Miao R, Li M, Zhang Q, Yang C, Wang X. An ECM-to-Nucleus Signaling Pathway Activates Lysosomes for C. elegans Larval Development. Developmental Cell. PMID 31735670 DOI: 10.1016/j.devcel.2019.10.020   
2019 Suda K, Muraoka Y, Ortega-Yáñez A, Yoshida H, Kizu F, Hochin T, Kimura H, Yamaguchi M. Reduction of Rpd3 suppresses defects in locomotive ability and neuronal morphology induced by the knockdown of Drosophila SLC25A46 via an epigenetic pathway. Experimental Cell Research. 111673. PMID 31614134 DOI: 10.1016/j.yexcr.2019.111673   
2019 Lakdawala MF, Madhu B, Faure L, Vora M, Padgett RW, Gumienny TL. Genetic interactions between the DBL-1/BMP-like pathway and body size-associated genes in . Molecular Biology of the Cell. mbcE19090500. PMID 31693440 DOI: 10.1091/mbc.E19-09-0500   
2019 Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K. Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding. Current Biology : Cb. PMID 31607533 DOI: 10.1016/j.cub.2019.09.025   
2019 Shigemura M, Lecuona E, Angulo M, Dada LA, Edwards MB, Welch LC, Casalino-Matsuda SM, Sporn PHS, Vadász I, Helenius IT, Nader GA, Gruenbaum Y, Sharabi K, Cummins E, Taylor C, et al. Elevated CO regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans. Scientific Reports. 9: 18251. PMID 31796806 DOI: 10.1038/s41598-019-54683-0   
2019 Barak Y, Hemberger M, Sucov HM. Correction to: Phases and Mechanisms of Embryonic Cardiomyocyte Proliferation and Ventricular Wall Morphogenesis. Pediatric Cardiology. PMID 31680222 DOI: 10.1007/s00246-019-02232-x   
2019 Arefin B, Parvin F, Bahrampour S, Stadler CB, Thor S. Drosophila Neuroblast Selection Is Gated by Notch, Snail, SoxB, and EMT Gene Interplay. Cell Reports. 29: 3636-3651.e3. PMID 31825841 DOI: 10.1016/j.celrep.2019.11.038   
2019 Dong G, Huang Y, Ding H, Luo L, Zhang Y, Huang H, Ruan H. Mypt1 regulates Bmp signaling to promote embryonic exocrine pancreas growth in zebrafish. Genesis (New York, N.Y. : 2000). e23345. PMID 31705616 DOI: 10.1002/dvg.23345   
2019 Das P, Salazar JL, Li-Kroeger D, Yamamoto S, Nakamura M, Sasamura T, Inaki M, Masuda W, Kitagawa M, Yamakawa T, Matsuno K. Maternal almondex, a neurogenic gene, is required for proper subcellular Notch distribution in early Drosophila embryogenesis. Development, Growth & Differentiation. PMID 31782145 DOI: 10.1111/dgd.12639   
2019 Li Y, Zhang F, Jiang N, Liu T, Shen J, Zhang J. Decapentaplegic signaling regulates Wingless ligand production and target activation during Drosophila wing development. Febs Letters. PMID 31814119 DOI: 10.1002/1873-3468.13713   
2019 Jarrett SM, Seegar TCM, Andrews M, Adelmant G, Marto JA, Aster JC, Blacklow SC. Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling. Science Signaling. 12. PMID 31690634 DOI: 10.1126/scisignal.aay2369   
2019 Pandey A, Harvey BM, Lopez MF, Ito A, Haltiwanger RS, Jafar-Nejad H. Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila. Cell Reports. 29: 2054-2066.e6. PMID 31722217 DOI: 10.1016/j.celrep.2019.10.027   
2019 Gu P, Gong J, Shang Y, Wang F, Ruppell KT, Ma Z, Sheehan AE, Freeman MR, Xiang Y. Polymodal Nociception in Drosophila Requires Alternative Splicing of TrpA1. Current Biology : Cb. PMID 31735672 DOI: 10.1016/j.cub.2019.09.070   
2019 van Soldt BJ, Cardoso WV. Hippo-Yap/Taz signaling: Complex network interactions and impact in epithelial cell behavior. Wiley Interdisciplinary Reviews. Developmental Biology. e371. PMID 31828974 DOI: 10.1002/wdev.371   
2019 Rolo A, Galea GL, Savery D, Greene NDE, Copp AJ. Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects. Disease Models & Mechanisms. PMID 31628096 DOI: 10.1242/dmm.040683