Kenneth Rhodes - Publications

Affiliations: 
1992 Anatomy and Neurobiology Boston University, Boston, MA, United States 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L, Maier M, Dunstan R, Salloway S, Chen T, Ling Y, O'Gorman J, Qian F, Arastu M, Li M, Chollate S, ... ... Rhodes K, et al. The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. Nature. 537: 50-6. PMID 27582220 DOI: 10.1038/nature19323  0.48
2016 Brennan MS, Patel H, Allaire N, Thai A, Cullen P, Ryan S, Lukashev M, Bista P, Huang R, Rhodes KJ, Scannevin RH. Pharmacodynamics of Dimethyl Fumarate are Tissue-specific and Involve NRF2-dependent and -independent Mechanisms. Antioxidants & Redox Signaling. PMID 26980071 DOI: 10.1089/ars.2015.6622  0.48
2015 Scannevin RH, Chollate S, Brennan MS, Snodgrass-Belt PA, Peng H, Xu L, Jung MY, Bussiere T, Arastu MF, Talreja T, Xin Z, Dunstan RW, Fahrer D, Rohde E, Dunah AW, ... ... Rhodes KJ, et al. BIIB042, a novel γ-secretase modulator, reduces amyloidogenic Aβ isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease. Neuropharmacology. PMID 26690893 DOI: 10.1016/j.neuropharm.2015.12.006  0.48
2015 Brennan MS, Matos MF, Li B, Hronowski X, Gao B, Juhasz P, Rhodes KJ, Scannevin RH. Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro. Plos One. 10: e0120254. PMID 25793262 DOI: 10.1371/journal.pone.0120254  0.48
2014 Atack JR, Shook BC, Rassnick S, Jackson PF, Rhodes K, Drinkenburg WH, Ahnaou A, Te Riele P, Langlois X, Hrupka B, De Haes P, Hendrickx H, Aerts N, Hens K, Wellens A, et al. JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's disease. Acs Chemical Neuroscience. 5: 1005-19. PMID 25203719 DOI: 10.1021/cn5001606  0.48
2014 Alfonso S, Kessels HW, Banos CC, Chan TR, Lin ET, Kumaravel G, Scannevin RH, Rhodes KJ, Huganir R, Guckian KM, Dunah AW, Malinow R. Synapto-depressive effects of amyloid beta require PICK1. The European Journal of Neuroscience. 39: 1225-33. PMID 24713001 DOI: 10.1111/ejn.12499  0.48
2013 Shook BC, Chakravarty D, Barbay JK, Wang A, Leonard K, Alford V, Powell MT, Rassnick S, Scannevin RH, Carroll K, Wallace N, Crooke J, Ault M, Lampron L, Westover L, ... Rhodes K, et al. Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 23: 2688-91. PMID 23522563 DOI: 10.1016/j.bmcl.2013.02.078  0.48
2012 Scannevin RH, Chollate S, Jung MY, Shackett M, Patel H, Bista P, Zeng W, Ryan S, Yamamoto M, Lukashev M, Rhodes KJ. Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway. The Journal of Pharmacology and Experimental Therapeutics. 341: 274-84. PMID 22267202 DOI: 10.1124/jpet.111.190132  0.48
2012 Shook BC, Rassnick S, Wallace N, Crooke J, Ault M, Chakravarty D, Barbay JK, Wang A, Powell MT, Leonard K, Alford V, Scannevin RH, Carroll K, Lampron L, Westover L, ... ... Rhodes K, et al. Design and characterization of optimized adenosine Aâ‚‚A/A₁ receptor antagonists for the treatment of Parkinson's disease. Journal of Medicinal Chemistry. 55: 1402-17. PMID 22239465 DOI: 10.1021/jm201640m  0.48
2011 Peng H, Talreja T, Xin Z, Cuervo JH, Kumaravel G, Humora MJ, Xu L, Rohde E, Gan L, Jung MY, Shackett MN, Chollate S, Dunah AW, Snodgrass-Belt PA, Arnold HM, ... ... Rhodes KJ, et al. Discovery of BIIB042, a Potent, Selective, and Orally Bioavailable γ-Secretase Modulator. Acs Medicinal Chemistry Letters. 2: 786-91. PMID 24900267 DOI: 10.1021/ml200175q  0.48
2011 Xin Z, Peng H, Zhang A, Talreja T, Kumaravel G, Xu L, Rohde E, Jung MY, Shackett MN, Kocisko D, Chollate S, Dunah AW, Snodgrass-Belt PA, Arnold HM, Taveras AG, ... Rhodes KJ, et al. Discovery of 4-aminomethylphenylacetic acids as γ-secretase modulators via a scaffold design approach. Bioorganic & Medicinal Chemistry Letters. 21: 7277-80. PMID 22061640 DOI: 10.1016/j.bmcl.2011.10.047  0.48
2011 Wilson LJ, Wang B, Yang SM, Scannevin RH, Burke SL, Karnachi P, Rhodes KJ, Murray WV. Discovery of novel Cobactin-T based matrix metalloproteinase inhibitors via a ring closing metathesis strategy. Bioorganic & Medicinal Chemistry Letters. 21: 6485-90. PMID 21925881 DOI: 10.1016/j.bmcl.2011.08.068  0.48
2011 Mi S, Lee X, Hu Y, Ji B, Shao Z, Yang W, Huang G, Walus L, Rhodes K, Gong BJ, Miller RH, Pepinsky RB. Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination. Nature Medicine. 17: 816-21. PMID 21725297 DOI: 10.1038/nm.2373  0.48
2011 Lim HK, Chen J, Sensenhauser C, Cook K, Preston R, Thomas T, Shook B, Jackson PF, Rassnick S, Rhodes K, Gopaul V, Salter R, Silva J, Evans DC. Overcoming the genotoxicity of a pyrrolidine substituted arylindenopyrimidine as a potent dual adenosine A(2A)/A(1) antagonist by minimizing bioactivation to an iminium ion reactive intermediate. Chemical Research in Toxicology. 24: 1012-30. PMID 21667953 DOI: 10.1021/tx1004437  0.48
2010 Shook BC, Rassnick S, Osborne MC, Davis S, Westover L, Boulet J, Hall D, Rupert KC, Heintzelman GR, Hansen K, Chakravarty D, Bullington JL, Russell R, Branum S, Wells KM, ... ... Rhodes K, et al. In vivo characterization of a dual adenosine A2A/A1 receptor antagonist in animal models of Parkinson's disease. Journal of Medicinal Chemistry. 53: 8104-15. PMID 20973483 DOI: 10.1021/jm100971t  0.48
2010 Shook BC, Rassnick S, Hall D, Rupert KC, Heintzelman GR, Hansen K, Chakravarty D, Bullington JL, Scannevin RH, Magliaro B, Westover L, Carroll K, Lampron L, Russell R, Branum S, ... ... Rhodes K, et al. Methylene amine substituted arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 2864-7. PMID 20347304 DOI: 10.1016/j.bmcl.2010.03.042  0.48
2010 Shook BC, Rassnick S, Chakravarty D, Wallace N, Ault M, Crooke J, Barbay JK, Wang A, Leonard K, Powell MT, Alford V, Hall D, Rupert KC, Heintzelman GR, Hansen K, ... ... Rhodes K, et al. Optimization of arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 2868-71. PMID 20338760 DOI: 10.1016/j.bmcl.2010.03.024  0.48
2008 Murata Y, Rosell A, Scannevin RH, Rhodes KJ, Wang X, Lo EH. Extension of the thrombolytic time window with minocycline in experimental stroke. Stroke; a Journal of Cerebral Circulation. 39: 3372-7. PMID 18927459 DOI: 10.1161/STROKEAHA.108.514026  0.48
2008 Rhodes KJ, Trimmer JS. Antibody-based validation of CNS ion channel drug targets. The Journal of General Physiology. 131: 407-13. PMID 18411328 DOI: 10.1085/jgp.200709926  0.48
2008 Yang SM, Scannevin RH, Wang B, Burke SL, Wilson LJ, Karnachi P, Rhodes KJ, Lagu B, Murray WV. beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. Design, synthesis, and lead identification. Bioorganic & Medicinal Chemistry Letters. 18: 1135-9. PMID 18086526 DOI: 10.1016/j.bmcl.2007.11.119  0.48
2008 Yang SM, Scannevin RH, Wang B, Burke SL, Huang Z, Karnachi P, Wilson LJ, Rhodes KJ, Lagu B, Murray WV. beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 2. Optimization of alpha-amino substituents. Bioorganic & Medicinal Chemistry Letters. 18: 1140-5. PMID 18083558 DOI: 10.1016/j.bmcl.2007.11.129  0.48
2008 Zhang YM, Fan X, Chakaravarty D, Xiang B, Scannevin RH, Huang Z, Ma J, Burke SL, Karnachi P, Rhodes KJ, Jackson PF. 1-Hydroxy-2-pyridinone-based MMP inhibitors: synthesis and biological evaluation for the treatment of ischemic stroke. Bioorganic & Medicinal Chemistry Letters. 18: 409-13. PMID 17981034 DOI: 10.1016/j.bmcl.2007.10.045  0.48
2008 Zhang YM, Fan X, Yang SM, Scannevin RH, Burke SL, Rhodes KJ, Jackson PF. Syntheses and in vitro evaluation of arylsulfone-based MMP inhibitors with heterocycle-derived zinc-binding groups (ZBGs). Bioorganic & Medicinal Chemistry Letters. 18: 405-8. PMID 17980583 DOI: 10.1016/j.bmcl.2007.10.049  0.48
2007 Lee SR, Guo SZ, Scannevin RH, Magliaro BC, Rhodes KJ, Wang X, Lo EH. Induction of matrix metalloproteinase, cytokines and chemokines in rat cortical astrocytes exposed to plasminogen activators. Neuroscience Letters. 417: 1-5. PMID 17386975 DOI: 10.1016/j.neulet.2007.01.017  0.48
2006 Rhodes KJ, Trimmer JS. Antibodies as valuable neuroscience research tools versus reagents of mass distraction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8017-20. PMID 16885215 DOI: 10.1523/JNEUROSCI.2728-06.2006  0.48
2006 Misonou H, Menegola M, Buchwalder L, Park EW, Meredith A, Rhodes KJ, Aldrich RW, Trimmer JS. Immunolocalization of the Ca2+-activated K+ channel Slo1 in axons and nerve terminals of mammalian brain and cultured neurons. The Journal of Comparative Neurology. 496: 289-302. PMID 16566008 DOI: 10.1002/cne.20931  0.48
2005 Strassle BW, Menegola M, Rhodes KJ, Trimmer JS. Light and electron microscopic analysis of KChIP and Kv4 localization in rat cerebellar granule cells. The Journal of Comparative Neurology. 484: 144-55. PMID 15736227 DOI: 10.1002/cne.20443  0.48
2005 Aimond F, Kwak SP, Rhodes KJ, Nerbonne JM. Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes. Circulation Research. 96: 451-8. PMID 15662035 DOI: 10.1161/01.RES.0000156890.25876.63  0.48
2004 Rhodes KJ, Carroll KI, Sung MA, Doliveira LC, Monaghan MM, Burke SL, Strassle BW, Buchwalder L, Menegola M, Cao J, An WF, Trimmer JS. KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7903-15. PMID 15356203 DOI: 10.1523/JNEUROSCI.0776-04.2004  0.48
2004 Scannevin RH, Wang K, Jow F, Megules J, Kopsco DC, Edris W, Carroll KC, Lü Q, Xu W, Xu Z, Katz AH, Olland S, Lin L, Taylor M, Stahl M, ... ... Rhodes KJ, et al. Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron. 41: 587-98. PMID 14980207 DOI: 10.1016/S0896-6273(04)00049-2  0.48
2004 Trimmer JS, Rhodes KJ. Localization of voltage-gated ion channels in mammalian brain. Annual Review of Physiology. 66: 477-519. PMID 14977411 DOI: 10.1146/annurev.physiol.66.032102.113328  0.48
2003 Shibata R, Misonou H, Campomanes CR, Anderson AE, Schrader LA, Doliveira LC, Carroll KI, Sweatt JD, Rhodes KJ, Trimmer JS. A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels. The Journal of Biological Chemistry. 278: 36445-54. PMID 12829703 DOI: 10.1074/jbc.M306142200  0.48
2002 Guo W, Li H, Aimond F, Johns DC, Rhodes KJ, Trimmer JS, Nerbonne JM. Role of heteromultimers in the generation of myocardial transient outward K+ currents. Circulation Research. 90: 586-93. PMID 11909823 DOI: 10.1161/01.RES.0000012664.05949.E0  0.48
2002 Beck EJ, Bowlby M, An WF, Rhodes KJ, Covarrubias M. Remodelling inactivation gating of Kv4 channels by KChIP1, a small-molecular-weight calcium-binding protein. The Journal of Physiology. 538: 691-706. PMID 11826158 DOI: 10.1113/jphysiol.2001.013127  0.48
2002 Holmqvist MH, Cao J, Hernandez-Pineda R, Jacobson MD, Carroll KI, Sung MA, Betty M, Ge P, Gilbride KJ, Brown ME, Jurman ME, Lawson D, Silos-Santiago I, Xie Y, Covarrubias M, ... Rhodes KJ, et al. Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 1035-40. PMID 11805342 DOI: 10.1073/pnas.022509299  0.48
2002 Campomanes CR, Carroll KI, Manganas LN, Hershberger ME, Gong B, Antonucci DE, Rhodes KJ, Trimmer JS. Kv beta subunit oxidoreductase activity and Kv1 potassium channel trafficking. The Journal of Biological Chemistry. 277: 8298-305. PMID 11748234 DOI: 10.1074/jbc.M110276200  0.48
1993 Rhodes KJ, Meiners KA, Rosene DL. A novel hinge system and incubation chamber for emulsion-coated coverslip autoradiography. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 41: 1419-27. PMID 8354882  0.48
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