James F. Brien - Publications

Affiliations: 
Queen's University, Canada, Kingston, Ontario, Canada 
Area:
Pharmacology, Neuroscience Biology

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Dobson CC, Thevasundaram K, Mongillo DL, Winterborn A, Holloway AC, Brien JF, Reynolds JN. Chronic prenatal ethanol exposure alters expression of central and peripheral insulin signaling molecules in adult guinea pig offspring. Alcohol (Fayetteville, N.Y.). 48: 687-93. PMID 25278255 DOI: 10.1016/J.Alcohol.2014.09.001  0.349
2014 Hewitt AJ, Dobson CC, Brien JF, Wynne-Edwards KE, Reynolds JN. Chronic ethanol exposure increases the non-dominant glucocorticoid, corticosterone, in the near-term pregnant guinea pig. Alcohol (Fayetteville, N.Y.). 48: 477-81. PMID 24961542 DOI: 10.1016/J.Alcohol.2014.06.005  0.409
2014 Parkington HC, Kenna KR, Sozo F, Coleman HA, Bocking A, Brien JF, Harding R, Walker DW, Morley R, Tare M. Maternal alcohol consumption in pregnancy enhances arterial stiffness and alters vasodilator function that varies between vascular beds in fetal sheep. The Journal of Physiology. 592: 2591-603. PMID 24756643 DOI: 10.1113/Jphysiol.2013.262873  0.341
2013 Sozo F, Dick AM, Bensley JG, Kenna K, Brien JF, Harding R, De Matteo R. Alcohol exposure during late ovine gestation alters fetal liver iron homeostasis without apparent dysmorphology. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R1121-9. PMID 23594612 DOI: 10.1152/Ajpregu.00479.2012  0.38
2013 Zelner I, Kenna K, Brien JF, Bocking A, Harding R, Walker D, Koren G. Meconium fatty acid ethyl esters as biomarkers of late gestational ethanol exposure and indicator of ethanol-induced multi-organ injury in fetal sheep. Plos One. 8: e59168. PMID 23533604 DOI: 10.1371/Journal.Pone.0059168  0.392
2012 Kenna K, Sozo F, De Matteo R, Hanita T, Gray SP, Tare M, Moritz K, Bertram JF, Black MJ, Brien JF, Parkington HC, Walker DW, Harding R. Alcohol exposure during late gestation: multiple developmental outcomes in sheep. Journal of Developmental Origins of Health and Disease. 3: 224-36. PMID 25102144 DOI: 10.1017/S2040174412000244  0.312
2012 Dobson CC, Mongillo DL, Brien DC, Stepita R, Poklewska-Koziell M, Winterborn A, Holloway AC, Brien JF, Reynolds JN. Chronic prenatal ethanol exposure increases adiposity and disrupts pancreatic morphology in adult guinea pig offspring. Nutrition & Diabetes. 2: e57. PMID 23247731 DOI: 10.1038/Nutd.2012.31  0.394
2012 Dobson CC, Mongillo DL, Poklewska-Koziell M, Winterborn A, Brien JF, Reynolds JN. Sensitivity of modified Biel-maze task, compared with Y-maze task, to measure spatial learning and memory deficits of ethanol teratogenicity in the guinea pig. Behavioural Brain Research. 233: 162-8. PMID 22562040 DOI: 10.1016/J.Bbr.2012.04.042  0.322
2012 Shea KM, Hewitt AJ, Olmstead MC, Brien JF, Reynolds JN. Maternal ethanol consumption by pregnant guinea pigs causes neurobehavioral deficits and increases ethanol preference in offspring. Behavioural Pharmacology. 23: 105-12. PMID 22157142 DOI: 10.1097/Fbp.0B013E32834Ed866  0.415
2011 Kenna K, De Matteo R, Hanita T, Rees S, Sozo F, Stokes V, Walker D, Bocking A, Brien J, Harding R. Daily ethanol exposure during late ovine pregnancy: physiological effects in the mother and fetus in the apparent absence of overt fetal cerebral dysmorphology. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R926-36. PMID 21715699 DOI: 10.1152/Ajpregu.00711.2010  0.382
2011 Hewitt AJ, Knuff AL, Jefkins MJ, Collier CP, Reynolds JN, Brien JF. Chronic ethanol exposure and folic acid supplementation: fetal growth and folate status in the maternal and fetal guinea pig. Reproductive Toxicology (Elmsford, N.Y.). 31: 500-6. PMID 21315145 DOI: 10.1016/J.Reprotox.2011.01.008  0.393
2011 Sozo F, Vela M, Stokes V, Kenna K, Meikle PJ, De Matteo R, Walker D, Brien J, Bocking A, Harding R. Effects of prenatal ethanol exposure on the lungs of postnatal lambs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L139-47. PMID 21036920 DOI: 10.1152/Ajplung.00195.2010  0.419
2010 Hewitt AJ, Walker KR, Kobus SM, Poklewska-Koziell M, Reynolds JN, Brien JF. Differential effects of chronic ethanol exposure on cytochrome P450 2E1 and the hypothalamic-pituitary-adrenal axis in the maternal-fetal unit of the guinea pig. Neurotoxicology and Teratology. 32: 164-70. PMID 20006703 DOI: 10.1016/J.Ntt.2009.12.002  0.416
2009 Olmstead MC, Martin A, Brien JF, Reynolds JN. Chronic prenatal ethanol exposure increases disinhibition and perseverative responding in the adult guinea pig. Behavioural Pharmacology. 20: 554-7. PMID 19633537 DOI: 10.1097/Fbp.0B013E3283305E27  0.403
2009 Sozo F, O'Day LD, Maritz G, Kenna KR, Stacy V, Brew N, Walker DW, Bocking AD, Brien JF, Harding R. Repeated ethanol exposure during late gestation alters the maturation and innate immune status of the ovine fetal lung American Journal of Physiology-Lung Cellular and Molecular Physiology. 296: 1-38. PMID 19112099 DOI: 10.1152/Ajplung.90532.2008  0.385
2008 Gray SP, Kenna K, Bertram JF, Hoy WE, Yan EB, Bocking AD, Brien JF, Walker DW, Harding R, Moritz KM. Repeated ethanol exposure during late gestation decreases nephron endowment in fetal sheep. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R568-74. PMID 18565833 DOI: 10.1152/Ajpregu.90316.2008  0.424
2008 McAdam TD, Brien JF, Reynolds JN, Dringenberg HC. Altered water-maze search behavior in adult guinea pigs following chronic prenatal ethanol exposure: lack of mitigation by postnatal fluoxetine treatment. Behavioural Brain Research. 191: 202-9. PMID 18455245 DOI: 10.1016/J.Bbr.2008.03.029  0.412
2007 Nash CM, Ibram F, Dringenberg HC, Reynolds JN, Brien JF. Effects of maternal administration of vitamins C and E on ethanol neurobehavioral teratogenicity in the guinea pig. Alcohol (Fayetteville, N.Y.). 41: 577-86. PMID 17980996 DOI: 10.1016/J.Alcohol.2007.08.005  0.385
2007 Nicolescu AC, Comeau JL, Hill BC, Bedard LL, Takahashi T, Brien JF, Racz WJ, Massey TE. Aryl radical involvement in amiodarone-induced pulmonary toxicity: investigation of protection by spin-trapping nitrones. Toxicology and Applied Pharmacology. 220: 60-71. PMID 17316728 DOI: 10.1016/J.Taap.2006.12.031  0.301
2006 Iqbal U, Brien JF, Kapoor A, Matthews SG, Reynolds JN. Chronic prenatal ethanol exposure increases glucocorticoid-induced glutamate release in the hippocampus of the near-term foetal guinea pig. Journal of Neuroendocrinology. 18: 826-34. PMID 17026532 DOI: 10.1111/J.1365-2826.2006.01479.X  0.357
2006 Green CR, Watts LT, Kobus SM, Henderson GI, Reynolds JN, Brien JF. Effects of chronic prenatal ethanol exposure on mitochondrial glutathione and 8-iso-prostaglandin F2alpha concentrations in the hippocampus of the perinatal guinea pig. Reproduction, Fertility, and Development. 18: 517-24. PMID 16836958 DOI: 10.1071/Rd05128  0.373
2006 Brien JF, Chan D, Green CR, Iqbal U, Gareri J, Kobus SM, McLaughlin BE, Klein J, Rao C, Reynolds JN, Bocking AD, Koren G. Chronic prenatal ethanol exposure and increased concentration of fatty acid ethyl esters in meconium of term fetal Guinea pig. Therapeutic Drug Monitoring. 28: 345-50. PMID 16778718 DOI: 10.1097/01.Ftd.0000211819.35182.82  0.433
2006 Kinobe RT, Vlahakis JZ, Vreman HJ, Stevenson DK, Brien JF, Szarek WA, Nakatsu K. Selectivity of imidazole-dioxolane compounds for in vitro inhibition of microsomal haem oxygenase isoforms. British Journal of Pharmacology. 147: 307-15. PMID 16331285 DOI: 10.1038/Sj.Bjp.0706555  0.323
2006 Green CR, Kobus SM, Ji Y, Bennett BM, Reynolds JN, Brien JF. Erratum to “Chronic prenatal ethanol exposure increases apoptosis in the hippocampus of the term fetal guinea pig” [Neurotoxicology and Teratology 27 (2005) 871–881] Neurotoxicology and Teratology. 28: 296-297. DOI: 10.1016/J.Ntt.2005.07.007  0.397
2005 Green CR, Kobus SM, Ji Y, Bennett BM, Reynolds JN, Brien JF. Chronic prenatal ethanol exposure increases apoptosis in the hippocampus of the term fetal guinea pig. Neurotoxicology and Teratology. 27: 871-81. PMID 16112842 DOI: 10.1016/J.Ntt.2005.07.006  0.398
2005 Iqbal U, Brien JF, Banjanin S, Andrews MH, Matthews SG, Reynolds JN. Chronic prenatal ethanol exposure alters glucocorticoid signalling in the hippocampus of the postnatal Guinea pig. Journal of Neuroendocrinology. 17: 600-8. PMID 16101899 DOI: 10.1111/J.1365-2826.2005.01349.X  0.435
2004 Byrnes ML, Richardson DP, Brien JF, Reynolds JN, Dringenberg HC. Spatial acquisition in the Morris water maze and hippocampal long-term potentiation in the adult guinea pig following brain growth spurt--prenatal ethanol exposure. Neurotoxicology and Teratology. 26: 543-51. PMID 15203176 DOI: 10.1016/J.Ntt.2004.04.005  0.43
2004 Jaronczyk K, Bui L, Soong JM, McLaughlin BE, Marks GS, Brien JF, Nakatsu K. The source of heme for vascular heme oxygenase II: de novo heme biosynthesis in rat aorta. Canadian Journal of Physiology and Pharmacology. 82: 218-24. PMID 15181459 DOI: 10.1139/Y04-015  0.309
2004 Bui L, Rish K, Jaronczyk K, Bourque S, McLaughlin BE, Brien JF, Marks GS, Smith A, Nakatsu K. The source of heme for vascular heme oxygenase I: heme uptake in rat aorta. Canadian Journal of Physiology and Pharmacology. 82: 209-17. PMID 15181458 DOI: 10.1139/Y04-014  0.301
2004 Nava-Ocampo AA, Velázquez-Armenta Y, Brien JF, Koren G. Elimination kinetics of ethanol in pregnant women. Reproductive Toxicology (Elmsford, N.Y.). 18: 613-7. PMID 15135856 DOI: 10.1016/J.Reprotox.2004.02.012  0.4
2004 Iqbal U, Dringenberg HC, Brien JF, Reynolds JN. Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig. Behavioural Brain Research. 150: 117-25. PMID 15033285 DOI: 10.1016/S0166-4328(03)00246-8  0.323
2004 Bailey CD, Brien JF, Reynolds JN. Chronic prenatal ethanol exposure alters the proportion of GABAergic neurons in layers II/III of the adult guinea pig somatosensory cortex. Neurotoxicology and Teratology. 26: 59-63. PMID 15001214 DOI: 10.1016/J.Ntt.2003.08.002  0.361
2004 Hayward ML, Martin AE, Brien JF, Dringenberg HC, Olmstead MC, Reynolds JN. Chronic prenatal ethanol exposure impairs conditioned responding and enhances GABA release in the hippocampus of the adult guinea pig. The Journal of Pharmacology and Experimental Therapeutics. 308: 644-50. PMID 14600252 DOI: 10.1124/Jpet.103.059261  0.363
2003 Puri RK, Reynolds JN, Brien JF. Effects of chronic prenatal ethanol exposure on NMDA receptor number and affinity for [3H]MK-801 in the cerebral cortex of the young postnatal and adult guinea-pig. Reproduction, Fertility, and Development. 15: 207-14. PMID 12921695 DOI: 10.1071/Rd03022  0.356
2003 McGoey TN, Reynolds JN, Brien JF. Chronic prenatal ethanol exposure-induced decrease of guinea pig hippocampal CA1 pyramidal cell and cerebellar Purkinje cell density. Canadian Journal of Physiology and Pharmacology. 81: 476-84. PMID 12774854 DOI: 10.1139/Y03-048  0.349
2003 Byrnes ML, Reynolds JN, Brien JF. Brain growth spurt-prenatal ethanol exposure and the guinea pig hippocampal glutamate signaling system. Neurotoxicology and Teratology. 25: 303-10. PMID 12757827 DOI: 10.1016/S0892-0362(02)00354-9  0.433
2003 Dettmer TS, Barnes A, Iqbal U, Bailey CD, Reynolds JN, Brien JF, Valenzuela CF. Chronic prenatal ethanol exposure alters ionotropic glutamate receptor subunit protein levels in the adult guinea pig cerebral cortex. Alcoholism, Clinical and Experimental Research. 27: 677-81. PMID 12711930 DOI: 10.1111/J.1530-0277.2003.Tb04404.X  0.396
2003 McLaughlin BE, Lash GE, Smith GN, Marks GS, Nakatsu K, Graham CH, Brien JF. Heme oxygenase expression in selected regions of term human placenta. Experimental Biology and Medicine (Maywood, N.J.). 228: 564-7. PMID 12709587 DOI: 10.1177/15353702-0322805-28  0.317
2003 Butters NS, Reynolds JN, Brien JF. Effects of chronic prenatal ethanol exposure on cGMP content and glutamate release in the hippocampus of the neonatal guinea pig. Neurotoxicology and Teratology. 25: 59-68. PMID 12633737 DOI: 10.1016/S0892-0362(02)00325-2  0.328
2002 Richardson DP, Byrnes ML, Brien JF, Reynolds JN, Dringenberg HC. Impaired acquisition in the water maze and hippocampal long-term potentiation after chronic prenatal ethanol exposure in the guinea-pig. The European Journal of Neuroscience. 16: 1593-8. PMID 12405973 DOI: 10.1046/J.1460-9568.2002.02214.X  0.406
2002 Hosein S, Marks GS, Brien JF, McLaughlin BE, Nakatsu K. An extracellular source of heme can induce a significant heme oxygenase mediated relaxation in the rat aorta. Canadian Journal of Physiology and Pharmacology. 80: 761-5. PMID 12269785 DOI: 10.1139/Y02-086  0.31
2001 McLaughlin BE, Lash GE, Graham CH, Smith GN, Vreman HJ, Stevenson DK, Marks GS, Nakatsu K, Brien JF. Endogenous carbon monoxide formation by chorionic villi of term human placenta. Placenta. 22: 886-8. PMID 11718578 DOI: 10.1053/Plac.2001.0729  0.3
2001 Butters NS, Reynolds JN, Brien JF. In vitro ethanol exposure decreases potassium-stimulated, but not veratridine-stimulated, glutamate release in the guinea pig hippocampus. Alcohol (Fayetteville, N.Y.). 25: 49-53. PMID 11668017 DOI: 10.1016/S0741-8329(01)00166-5  0.364
2001 Byrnes ML, Reynolds JN, Brien JF. Effect of prenatal ethanol exposure during the brain growth spurt of the guinea pig. Neurotoxicology and Teratology. 23: 355-64. PMID 11485838 DOI: 10.1016/S0892-0362(01)00150-7  0.429
2001 Bailey CDC, Brien JF, Reynolds JN. Chronic Prenatal Ethanol Exposure Increases GABAAReceptor Subunit Protein Expression in the Adult Guinea Pig Cerebral Cortex The Journal of Neuroscience. 21: 4381-4389. DOI: 10.1523/Jneurosci.21-12-04381.2001  0.425
2000 Crowe AC, Chang ME, McLaughlin BE, Brien JF. Nitric oxide formation from glyceryl trinitrate in the developing guinea-pig hippocampus. Reproduction, Fertility, and Development. 12: 245-9. PMID 11451014 DOI: 10.1071/Rd00090  0.3
2000 Kimura KA, Reynolds JN, Brien JF. Ethanol neurobehavioral teratogenesis and the role of the hippocampal glutamate-N-methyl-D-aspartate receptor-nitric oxide synthase system. Neurotoxicology and Teratology. 22: 607-16. PMID 11106855 DOI: 10.1016/S0892-0362(00)00089-1  0.375
2000 McLaughlin BE, Hutchinson JM, Graham CH, Smith GN, Marks GS, Nakatsu K, Brien JF. Heme oxygenase activity in term human placenta. Placenta. 21: 870-3. PMID 11095937 DOI: 10.1053/Plac.2000.0574  0.328
2000 Butters NS, Gibson MA, Reynolds JN, Brien JF. Effects of chronic prenatal ethanol exposure on hippocampal glutamate release in the postnatal guinea pig. Alcohol (Fayetteville, N.Y.). 21: 1-9. PMID 10946152 DOI: 10.1016/S0741-8329(99)00096-8  0.406
2000 Spear-Smith J, Brien JF, Grafe M, Allrich R, Reynolds JD. Chronic ethanol exposure during late gestation produces behavioral anomalies in neonatal lambs. Neurotoxicology and Teratology. 22: 205-12. PMID 10758349 DOI: 10.1016/S0892-0362(99)00059-8  0.413
2000 Gibson MA, Butters NS, Reynolds JN, Brien JF. Effects of chronic prenatal ethanol exposure on locomotor activity, and hippocampal weight, neurons, and nitric oxide synthase activity of the young postnatal guinea pig. Neurotoxicology and Teratology. 22: 183-92. PMID 10758347 DOI: 10.1016/S0892-0362(99)00074-4  0.404
2000 McLaughlin BE, Chretien ML, Choi C, Brien JF, Nakatsu K, Marks GS. Potentiation of carbon monoxide-induced relaxation of rat aorta by YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] Canadian Journal of Physiology and Pharmacology. 78: 343-349. DOI: 10.1139/Y99-145  0.333
1999 Kimura KA, Reynolds JN, Brien JF. Ontogeny of nitric oxide synthase I and III protein expression and enzymatic activity in the guinea pig hippocampus Developmental Brain Research. 116: 211-216. PMID 10521566 DOI: 10.1016/S0165-3806(99)00083-8  0.312
1999 Watson CS, White SE, Homan JH, Fraher L, Brien JF, Bocking AD. The adenosine A(1)-receptor antagonist 8-CPT reverses ethanol-induced inhibition of fetal breathing movements. Journal of Applied Physiology (Bethesda, Md. : 1985). 87: 1333-8. PMID 10517760 DOI: 10.1152/Jappl.1999.87.4.1333  0.343
1999 Kimura KA, Chiu J, Reynolds JN, Brien JF. Effect of chronic prenatal ethanol exposure on nitric oxide synthase I and III proteins in the hippocampus of the near-term fetal guinea pig Neurotoxicology and Teratology. 21: 251-259. PMID 10386828 DOI: 10.1016/S0892-0362(98)00055-5  0.436
1999 Chiu J, Brien JF, Wu P, Eubanks JH, Zhang L, Reynolds JN. Chronic ethanol exposure alters MK-801 binding sites in the cerebral cortex of the near-term fetal guinea pig Alcohol. 17: 215-221. PMID 10231169 DOI: 10.1016/S0741-8329(98)00050-0  0.429
1999 Watson CS, White SE, Homan JH, Kimura KA, Brien JF, Fraher L, Challis JR, Bocking AD. Increased cerebral extracellular adenosine and decreased PGE2 during ethanol-induced inhibition of FBM. Journal of Applied Physiology (Bethesda, Md. : 1985). 86: 1410-20. PMID 10194230 DOI: 10.1152/Jappl.1999.86.4.1410  0.388
1999 Bailey CDC, Brien JF, Reynolds JN. Altered GABAA‐Benzodiazepine Receptor Number and Pharmacology in the Adult Guinea Pig Cerebral Cortex After Chronic Prenatal Ethanol Exposure Alcoholism: Clinical and Experimental Research. 23: 1816-1824. DOI: 10.1111/J.1530-0277.1999.Tb04078.X  0.365
1998 Odrcich MJ, Graham CH, Kimura KA, McLaughlin BE, Marks GS, Nakatsu K, Brien JF. Heme oxygenase and nitric oxide synthase in the placenta of the guinea-pig during gestation. Placenta. 19: 509-16. PMID 9778124 DOI: 10.1016/S0143-4004(98)91044-X  0.343
1998 Smith GN, Brien JF. Use of Nitroglycerin for Uterine Relaxation Obstetrical & Gynecological Survey. 53: 559-565. PMID 9751938 DOI: 10.1097/00006254-199809000-00023  0.31
1998 Kimura KA, Brien JF. Hippocampal nitric oxide synthase in the fetal guinea pig: effects of chronic prenatal ethanol exposure Developmental Brain Research. 106: 39-46. PMID 9554946 DOI: 10.1016/S0165-3806(97)00184-3  0.396
1997 Marks GS, McLaughlin BE, Vreman HJ, Stevenson DK, Nakatsu K, Brien JF, Pang SC. Heme oxygenase activity and immunohistochemical localization in bovine pulmonary artery and vein. Journal of Cardiovascular Pharmacology. 30: 1-6. PMID 9268214 DOI: 10.1097/00005344-199707000-00001  0.303
1997 Cook MN, Marks GS, Vreman HJ, McLaughlin BE, Nakatsu K, Stevenson DK, Brien JF. Carbon monoxide formation in the guinea pig hippocampus: ontogeny and effect of in vitro ethanol exposure. Brain Research. Developmental Brain Research. 101: 283-6. PMID 9263603 DOI: 10.1016/S0165-3806(97)00063-1  0.425
1997 Cook MN, Marks GS, Vreman HJ, Nakatsu K, Stevenson DK, Brien JF. Heme oxygenase activity and acute and chronic ethanol exposure in the hippocampus, frontal cerebral cortex, and cerebellum of the near-term fetal guinea pig. Alcohol (Fayetteville, N.Y.). 14: 117-24. PMID 9085711 DOI: 10.1016/S0741-8329(96)00114-0  0.432
1997 Cook MN, Marks GS, Vreman HJ, Nakatsu K, Stevenson DK, Brien JF. Ontogeny of heme oxygenase activity in the hippocampus, frontal cerebral cortex, and cerebellum of the guinea pig. Brain Research. Developmental Brain Research. 92: 18-23. PMID 8861718 DOI: 10.1016/0165-3806(95)00194-8  0.305
1997 Reynolds JD, Penning DH, Kimura KA, Dexter F, Henderson JL, Atkins B, Poduska D, Brien JF. Ethanol‐Induced Changes in Prostaglandin E Concentration in the Intact Cerebral Cortex of Preterm and Near‐term Fetal Sheep Alcoholism: Clinical and Experimental Research. 21: 997-1004. DOI: 10.1111/J.1530-0277.1997.Tb04244.X  0.422
1996 Leeder RG, Rafeiro E, Brien JF, Mandin CC, Massey TE. Evaluation of reactive oxygen species involvement in amiodarone pulmonary toxicity in vivo and in vitro. Journal of Biochemical Toxicology. 11: 147-160. PMID 9029274 DOI: 10.1002/(Sici)1522-7146(1996)11:3<147::Aid-Jbt7>3.0.Co;2-K  0.314
1996 Watson CS, White SE, Homan J, Abdollah S, Brien JF, Challis JR, Bocking AD. Fetal breathing is not inhibited by ethanol exposure during prolonged reduced uterine blood flow. Canadian Journal of Physiology and Pharmacology. 74: 1016-24. PMID 8960393 DOI: 10.1139/Cjpp-74-9-1016  0.317
1996 Kimura KA, Parr AM, Brien JF. Effect of chronic maternal ethanol administration on nitric oxide synthase activity in the hippocampus of the mature fetal guinea pig Alcoholism: Clinical and Experimental Research. 20: 948-953. PMID 8865973 DOI: 10.1111/J.1530-0277.1996.Tb05276.X  0.443
1996 Reynolds JD, Penning DH, Dexter F, Atkins B, Hrdy J, Poduska D, Brien JF. Ethanol increases uterine blood flow and fetal arterial blood oxygen tension in the near-term pregnant ewe. Alcohol. 13: 251-256. PMID 8734839 DOI: 10.1016/0741-8329(95)02051-9  0.419
1995 Catlin M, Penning D, Brien J. Effect of exposure in vitro to ethanol and hypoxia on gamma-aminobutyric acid efflux in the hippocampus of the fetal and adult guinea-pig. Reproduction, Fertility and Development. 7: 1339-1344. PMID 8848609 DOI: 10.1071/Rd9951339  0.383
1995 Reynolds JD, Penning DH, Dexter F, Atkins B, Hrdy J, Poduska D, Chestnut DH, Brien JF. Dose-dependent effects of acute in vivo ethanol exposure on extracellular glutamate concentration in the cerebral cortex of the near-term fetal sheep Alcoholism: Clinical and Experimental Research. 19: 1447-1453. PMID 8749809 DOI: 10.1111/J.1530-0277.1995.Tb01006.X  0.406
1995 Liu ZG, McLaughlin BE, Marks GS, Brien JF, Nakatsu K. Sulfhydryl involvement in nitric oxide sequestration and nitric oxide induced guanylyl cyclase activation in vascular smooth muscle. Canadian Journal of Physiology and Pharmacology. 73: 1144-8. PMID 8564882 DOI: 10.1139/Y95-163  0.316
1995 Bozinovski J, Brien JF, Marks GS, Nakatsu K. Inhibition of nitrovasodilators by pyocyanin and methylene blue is dissociated from nitric oxide formation. Canadian Journal of Physiology and Pharmacology. 72: 746-52. PMID 7828082 DOI: 10.1139/Y94-106  0.313
1995 Reynolds JD, Brien JF. The role of adenosine A1 receptor activation in ethanol-induced inhibition of stimulated glutamate release in the hippocampus of the fetal and adult guinea pig. Alcohol. 12: 151-157. PMID 7772267 DOI: 10.1016/0741-8329(94)00078-6  0.392
1995 Cook MN, Nakatsu K, Marks GS, McLaughlin BE, Vreman HJ, Stevenson DK, Brien JF. Heme oxygenase activity in the adult rat aorta and liver as measured by carbon monoxide formation. Canadian Journal of Physiology and Pharmacology. 73: 515-8. PMID 7671194 DOI: 10.1139/Y95-065  0.309
1995 Abdollah S, Brien JF. Effect of chronic maternal ethanol administration on glutamate and N-methyl-D-aspartate binding sites in the hippocampus of the near-term fetal guinea pig. Alcohol. 12: 377-382. PMID 7546336 DOI: 10.1016/0741-8329(95)00021-I  0.401
1995 Abdollah S, Brien JF. Glutamate and N-methyl-d-aspartate binding sites in the guinea pig hippocampus: Ontogeny and effect of acute in vitro ethanol exposure Alcohol. 12: 369-375. PMID 7546335 DOI: 10.1016/0741-8329(95)00020-R  0.31
1995 Brien JF, Reynolds JD, Cunningham MA, Parr AM, Waddock S, Kalisch BE. Nitric oxide synthase activity in the hippocampus, frontal cerebral cortex, and cerebellum of the guinea pig: Ontogeny and in vitro ethanol exposure Alcohol. 12: 329-333. PMID 7546328 DOI: 10.1016/0741-8329(95)00006-D  0.417
1994 Bocking AD, Carmichael LJ, Abdollah S, Sinervo KR, Smith GN, Brien JF. Effect of ethanol on immature ovine fetal breathing movements, fetal prostaglandin E2, and myometrial activity. The American Journal of Physiology. 266: R1297-301. PMID 8184974 DOI: 10.1152/Ajpregu.1994.266.4.R1297  0.377
1994 Reynolds JD, Brien JF. Effects of acute ethanol exposure on glutamate release in the hippocampus of the fetal and adult guinea pig. Alcohol. 11: 259-267. PMID 7914730 DOI: 10.1016/0741-8329(94)90040-X  0.403
1993 Catlin MC, Abdollah S, Brien JF. Dose-dependent effects of prenatal ethanol exposure in the guinea pig Alcohol. 10: 109-115. PMID 8442887 DOI: 10.1016/0741-8329(93)90089-7  0.425
1993 Abdollah S, Catlin MC, Brien JF. Ethanol neuro-behavioural teratogenesis in the guinea pig : behavioural dysfunction and hippocampal morphologic change Canadian Journal of Physiology and Pharmacology. 71: 776-782. PMID 8143236 DOI: 10.1139/Y93-116  0.4
1992 Sinervo KR, Smith GN, Bocking AD, Patrick J, Brien JF. Effect of ethanol on the release of prostaglandins from ovine fetal brain stem during gestation Alcoholism: Clinical and Experimental Research. 16: 443-448. PMID 1626643 DOI: 10.1111/J.1530-0277.1992.Tb01397.X  0.39
1992 Marks GS, McLaughlin BE, Nakatsu K, Brien JF. Direct evidence for nitric oxide formation from glyceryl trinitrate during incubation with intact bovine pulmonary artery. Canadian Journal of Physiology and Pharmacology. 70: 308-11. PMID 1521184 DOI: 10.1139/Y92-039  0.309
1992 Marks GS, McLaughlin BE, Nakatsu K, Brien JF. Biotransformation of glyceryl trinitrate by rat brain homogenate. Canadian Journal of Physiology and Pharmacology. 70: 935-7. PMID 1423038 DOI: 10.1139/Y92-127  0.305
1991 Treissman D, Brien JF. Fetal guinea pig brain 15-hydroxyprostaglandin dehydrogenase: Ontogeny and effect of ethanol Alcohol. 8: 97-102. PMID 2064759 DOI: 10.1016/0741-8329(91)91316-T  0.389
1991 Smith GN, Patrick J, Sinervo KR, Brien JF. Effects of ethanol exposure on the embryo-fetus: experimental considerations, mechanisms, and the role of prostaglandins. Canadian Journal of Physiology and Pharmacology. 69: 550-569. PMID 1863905 DOI: 10.1139/Y91-082  0.41
1991 Treissman D, Smith GN, Patrick J, Brien JF. Effect of ethanol on 15-hydroxyprostaglandin dehydrogenase activity in the brain stem of the near-term fetal sheep. Developmental Pharmacology and Therapeutics. 16: 48-52. DOI: 10.1159/000480555  0.415
1990 Smith GN, Patrick J, Brien JF. Functional tolerance to the effects of ethanol on fetal biophysical activities American Journal of Obstetrics and Gynecology. 162: 1631-1632. PMID 2360599 DOI: 10.1016/0002-9378(90)90938-4  0.392
1990 Daniels JM, Leeder RG, Brien JF, Massey TE. Repeated amiodarone exposure in the rat: toxicity and effects on hepatic and extrahepatic monooxygenase activities. Canadian Journal of Physiology and Pharmacology. 68: 1261-8. PMID 2276089 DOI: 10.1139/Y90-189  0.326
1989 Card SE, Brien JF. No effect of chronic ethanol administration on the activity of alcohol dehydrogenase and aldehyde dehydrogenases in the near-term pregnant guinea pig. Canadian Journal of Physiology and Pharmacology. 67: 601-606. PMID 2776078 DOI: 10.1139/Y89-096  0.372
1989 Card SE, Tompkins SF, Brien JF. Ontogeny of the activity of alcohol dehydrogenase and aldehyde dehydrogenases in the liver and placenta of the guinea pig Biochemical Pharmacology. 38: 2535-2541. PMID 2757651 DOI: 10.1016/0006-2952(89)90099-3  0.39
1989 Smith GN, Brien JF, Carmichael L, Clarke DW, Patrick J. Effect of acute, multiple-dose ethanol on maternal and fetal blood gases and acid-base balance in the near-term pregnant ewe. Canadian Journal of Physiology and Pharmacology. 67: 686-8. PMID 2505916 DOI: 10.1139/Y89-110  0.429
1989 Marks GS, McLaughlin BE, MacMillan HF, Nakatsu K, Brien JF. Differential biotransformation of glyceryl trinitrate by red blood cell-supernatant fraction and pulmonary vein homogenate. Canadian Journal of Physiology and Pharmacology. 67: 417-22. PMID 2504466 DOI: 10.1139/Y89-066  0.316
1989 Clarke DW, Smith GN, Patrick J, Richardson B, Brien JF. Activity of alcohol dehydrogenase and aldehyde dehydrogenase in maternal liver, fetal liver and placenta of the near-term pregnant ewe. Developmental Pharmacology and Therapeutics. 12: 35-41. DOI: 10.1159/000480980  0.374
1988 Slack CJ, McLaughlin BE, Nakatsu K, Marks GS, Brien JF. Nitric oxide-induced vasodilation of organic nitrate-tolerant rabbit aorta. Canadian Journal of Physiology and Pharmacology. 66: 1344-6. PMID 3149205 DOI: 10.1139/Y88-220  0.308
1987 Clarke DW, Patrick J, Wlodek ME, Smith GN, Richardson B, Brien JF. The role of fetal urinary excretion in the transfer of ethanol into amniotic fluid after maternal administration of ethanol to the near-term pregnant ewe. Canadian Journal of Physiology and Pharmacology. 65: 1120-1124. PMID 3621059 DOI: 10.1139/Y87-176  0.421
1986 Clarke DW, Steenaart NAE, Slack CJ, Brien JF. Pharmacokinetics of ethanol and its metabolite, acetaldehyde, and fetolethality in the third-trimester pregnant guinea pig for oral administration of acute, multiple-dose ethanol. Canadian Journal of Physiology and Pharmacology. 64: 1060-1067. PMID 3791045 DOI: 10.1139/Y86-182  0.432
1986 Clarke DW, Steenaart NAE, Brien JF. Disposition of ethanol and activity of hepatic and placental alcohol dehydrogenase and aldehyde dehydrogenases in the third-trimester pregnant guinea pig for single and short-term oral ethanol administration. Alcoholism: Clinical and Experimental Research. 10: 330-336. PMID 3526959 DOI: 10.1111/J.1530-0277.1986.Tb05099.X  0.429
1985 Richardson BS, Patrick JE, Bousquet J, Homan J, Brien JF. Cerebral metabolism in fetal lamb after maternal infusion of ethanol American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 249. PMID 4061674 DOI: 10.1152/Ajpregu.1985.249.5.R505  0.372
1985 Steenaart NAE, Clarke DW, Brien JF. Gas-liquid chromatographic analysis of ethanol and acetaldehyde in blood with minimal artifactual acetaldehyde formation Journal of Pharmacological Methods. 14: 199-212. PMID 4058017 DOI: 10.1016/0160-5402(85)90033-6  0.391
1985 Brien JF, Tam GS, Cameron RJ, Steenaart NA, Loomis CW. A comparative study of the inhibition of hepatic aldehyde dehydrogenases in the rat by methyltetrazolethiol, calcium carbimide, and disulfiram Canadian Journal of Physiology and Pharmacology. 63: 438-443. PMID 4041987 DOI: 10.1139/Y85-076  0.354
1985 Brien JF, Clarke DW, Richardson B, Patrick J. Disposition of ethanol in maternal blood, fetal blood, and amniotic fluid of third-trimester pregnant ewes. American Journal of Obstetrics and Gynecology. 152: 583-590. PMID 4014353 DOI: 10.1016/0002-9378(85)90632-5  0.394
1985 Clarke DW, Steenaart NAE, Breedon TH, Brien JF. Differential pharmacokinetics for oral and intraperitoneal administration of ethanol to the pregnant guinea pig Canadian Journal of Physiology and Pharmacology. 63: 169-172. PMID 3986701 DOI: 10.1139/Y85-033  0.424
1983 Brien JF, Loomis CW, Tranmer J, McGrath M. Disposition of ethanol in human maternal venous blood and amniotic fluid American Journal of Obstetrics and Gynecology. 146: 181-186. PMID 6846436 DOI: 10.1016/0002-9378(83)91050-5  0.396
1980 Brien JF, Hoover DJ. Gas-liquid chromatographic determination of ethanol and acetaldehyde in tissues Journal of Pharmacological Methods. 4: 51-58. PMID 7401649 DOI: 10.1016/0160-5402(80)90043-1  0.395
1980 Peachey JE, Brien JF, Loomis CW, Rogers BJ. A study of the calcium carbimide-ethanol interaction in man: symptom responses. Alcoholism, Clinical and Experimental Research. 4: 322-9. PMID 6996519 DOI: 10.1111/J.1530-0277.1980.Tb04822.X  0.352
1978 Brien JF, Loomis CW. Gas-liquid chromatographic determination of ethanol and acetaldehyde in blood. Clinica Chimica Acta. 87: 175-180. PMID 668140 DOI: 10.1016/0009-8981(78)90073-6  0.344
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