Xiao-Jiang Li - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Molecular Biology, Neuroscience Biology, Genetics

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Year Citation  Score
2024 Zhu L, Deng F, Bai D, Hou J, Jia Q, Zhang C, Ou K, Li S, Li XJ, Yin P. Loss of TDP-43 mediates severe neurotoxicity by suppressing PJA1 gene transcription in the monkey brain. Cellular and Molecular Life Sciences : Cmls. 81: 16. PMID 38194085 DOI: 10.1007/s00018-023-05066-2  0.324
2023 Tong H, Yang T, Liu L, Li C, Sun Y, Jia Q, Qin Y, Chen L, Zhao X, Zhou G, Yan S, Li XJ, Li S. Aberrant splicing of mutant huntingtin in Huntington's disease knock-in pigs. Neurobiology of Disease. 187: 106291. PMID 37716514 DOI: 10.1016/j.nbd.2023.106291  0.408
2023 Li C, Lin Y, Chen Y, Song X, Zheng X, Li J, He J, Chen X, Huang C, Wang W, Wu J, Wu J, Gao J, Tu Z, Li XJ, et al. A Specific Mini-Intrabody Mediates Lysosome Degradation of Mutant Huntingtin. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2301120. PMID 37688357 DOI: 10.1002/advs.202301120  0.425
2023 Liu L, Tong H, Sun Y, Chen X, Yang T, Zhou G, Li XJ, Li S. Huntingtin Interacting Proteins and Pathological Implications. International Journal of Molecular Sciences. 24. PMID 37685866 DOI: 10.3390/ijms241713060  0.323
2023 Pan Y, Tang B, Li XJ, Li S, Liu Q. Rhes depletion promotes striatal accumulation and aggregation of mutant huntingtin in a presymptomatic HD mouse model. Frontiers in Aging Neuroscience. 15: 1237018. PMID 37637962 DOI: 10.3389/fnagi.2023.1237018  0.358
2023 Yang S, Ma J, Zhang H, Chen L, Li Y, Pan M, Zhu H, Liang J, He D, Li S, Li XJ, Guo X. Mutant HTT does not affect glial development but impairs myelination in the early disease stage. Frontiers in Neuroscience. 17: 1238306. PMID 37539389 DOI: 10.3389/fnins.2023.1238306  0.379
2023 Bai D, Zhu L, Jia Q, Duan X, Chen L, Wang X, Hou J, Jiang G, Yang S, Li S, Li XJ, Yin P. Loss of TDP-43 promotes somatic CAG repeat expansion in Huntington's disease knock-in mice. Progress in Neurobiology. 227: 102484. PMID 37315918 DOI: 10.1016/j.pneurobio.2023.102484  0.34
2023 Yan S, Zheng X, Lin Y, Li C, Liu Z, Li J, Tu Z, Zhao Y, Huang C, Chen Y, Li J, Song X, Han B, Wang W, Liang W, ... ... Li XJ, et al. Cas9-mediated replacement of expanded CAG repeats in a pig model of Huntington's disease. Nature Biomedical Engineering. PMID 36797418 DOI: 10.1038/s41551-023-01007-3  0.311
2022 Jia Q, Li S, Li XJ, Yin P. Neuroinflammation in Huntington's disease: From animal models to clinical therapeutics. Frontiers in Immunology. 13: 1088124. PMID 36618375 DOI: 10.3389/fimmu.2022.1088124  0.33
2022 Zhao X, Sun Y, Wang Z, Chen L, Li S, Li XJ. Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice. Frontiers in Cellular Neuroscience. 16: 1021592. PMID 36439204 DOI: 10.3389/fncel.2022.1021592  0.369
2022 Chen X, Sun Y, Chen L, Chen XS, Pan M, Zhang Y, Wang Q, Yang W, Yin P, He D, Guo X, Yang S, Zeng Y, Yan S, Li XJ, et al. Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains. Cellular and Molecular Life Sciences : Cmls. 79: 554. PMID 36251080 DOI: 10.1007/s00018-022-04577-8  0.425
2021 Yin P, Bai D, Deng F, Zhang C, Jia Q, Zhu L, Chen L, Li B, Guo X, Ye J, Tan Z, Wang L, Li S, Li XJ. SQSTM1-mediated clearance of cytoplasmic mutant TARDBP/TDP-43 in the monkey brain. Autophagy. 1-14. PMID 34936539 DOI: 10.1080/15548627.2021.2013653  0.33
2021 Yang W, Guo X, Tu Z, Chen X, Han R, Liu Y, Yan S, Wang Q, Wang Z, Zhao X, Zhang Y, Xiong X, Yang H, Yin P, Wan H, ... ... Li XJ, et al. PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis. Protein & Cell. PMID 34800266 DOI: 10.1007/s13238-021-00888-x  0.305
2021 Yin P, Bai D, Zhu L, Deng F, Guo X, Li B, Chen L, Li S, Li XJ. Cytoplasmic TDP-43 impairs the activity of the ubiquitin-proteasome system. Experimental Neurology. 113833. PMID 34363810 DOI: 10.1016/j.expneurol.2021.113833  0.358
2021 Jing L, Cheng S, Pan Y, Liu Q, Yang W, Li S, Li XJ. Accumulation of Endogenous Mutant Huntingtin in Astrocytes Exacerbates Neuropathology of Huntington Disease in Mice. Molecular Neurobiology. PMID 34250577 DOI: 10.1007/s12035-021-02451-5  0.475
2021 Bai D, Yin P, Zhang Y, Sun F, Chen L, Lin L, Yan S, Li S, Li XJ. Lack of association of somatic CAG repeat expansion with striatal neurodegeneration in HD knock-in animal models. Human Molecular Genetics. PMID 33949657 DOI: 10.1093/hmg/ddab129  0.355
2021 Zhang XY, Li J, Li CJ, Lin YQ, Huang CH, Zheng X, Song XC, Tu ZC, Li XJ, Yan S. Differential development and electrophysiological activity in cultured cortical neurons from the mouse and cynomolgus monkey. Neural Regeneration Research. 16: 2446-2452. PMID 33907033 DOI: 10.4103/1673-5374.313056  0.302
2020 Liu Q, Cheng S, Yang H, Zhu L, Pan Y, Jing L, Tang B, Li S, Li XJ. Loss of Hap1 selectively promotes striatal degeneration in Huntington disease mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32747555 DOI: 10.1073/Pnas.2002283117  0.559
2020 Chen X, Xin N, Pan Y, Zhu L, Yin P, Liu Q, Yang W, Xu X, Li S, Li XJ. Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response. Frontiers in Cellular Neuroscience. 14: 125. PMID 32581713 DOI: 10.3389/Fncel.2020.00125  0.446
2020 Yang H, Yang S, Jing L, Huang L, Chen L, Zhao X, Yang W, Pan Y, Yin P, Qin ZS, Li S, Li XJ. Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form. Nature Communications. 11: 2582. PMID 32444599 DOI: 10.1038/S41467-020-16318-1  0.546
2020 Yin P, Liu Q, Pan Y, Yang W, Yang S, Wei W, Chen X, Hong Y, Bai D, Li XJ, Li S. Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease. Embo Reports. e49783. PMID 32270922 DOI: 10.15252/Embr.201949783  0.426
2020 Liu Q, Huang S, Yin P, Yang S, Zhang J, Jing L, Cheng S, Tang B, Li XJ, Pan Y, Li S. Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17. Nature Communications. 11: 1101. PMID 32107387 DOI: 10.1038/S41467-020-14931-8  0.526
2020 Yang S, Yang H, Huang L, Chen L, Qin Z, Li S, Li XJ. Lack of RAN-mediated toxicity in Huntington's disease knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32029588 DOI: 10.1073/Pnas.1919197117  0.434
2019 Pan Y, Liu Q, Zhang J, Yang Y, Tian Y, Zeng J, Yin P, Mei L, Xiong WC, Li XJ, Li S, Tang B. PRRT2 frameshift mutation reduces its mRNA stability resulting loss of function in paroxysmal kinesigenic dyskinesia. Biochemical and Biophysical Research Communications. PMID 31785815 DOI: 10.1016/J.Bbrc.2019.11.025  0.374
2019 Liu Q, Pan Y, Li XJ, Li S. Molecular Mechanisms and Therapeutics for SCA17. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31317427 DOI: 10.1007/S13311-019-00762-Z  0.478
2019 Yan S, Li S, Li XJ. Use of large animal models to investigate Huntington's diseases. Cell Regeneration (London, England). 8: 9-11. PMID 31205683 DOI: 10.1016/J.Cr.2019.01.001  0.39
2019 Ting LL, Lu HT, Yen SF, Ngo TH, Tu FY, Tsai IS, Tsai YH, Chang FY, Li XJ, Li S, Lee CK, Kao SH, Kuo YM, Lin YF. Expression of AHI1 Rescues Amyloidogenic Pathology in Alzheimer's Disease Model Cells. Molecular Neurobiology. PMID 31062249 DOI: 10.1007/S12035-019-1587-1  0.368
2019 Yang W, Li S, Li XJ. A CRISPR monkey model unravels a unique function of PINK1 in primate brains. Molecular Neurodegeneration. 14: 17. PMID 31046796 DOI: 10.1186/S13024-019-0321-9  0.384
2019 Zhu L, Chen L, Yan L, Perkins BD, Li S, Li B, Xu HA, Li XJ. Mutant Ahi1 Affects Retinal Axon Projection in Zebrafish Toxic Gain of Function. Frontiers in Cellular Neuroscience. 13: 81. PMID 30949029 DOI: 10.3389/Fncel.2019.00081  0.335
2019 Yin P, Guo X, Yang W, Yan S, Yang S, Zhao T, Sun Q, Liu Y, Li S, Li XJ. Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathologica. PMID 30810811 DOI: 10.1007/S00401-019-01979-0  0.429
2019 Yang W, Liu Y, Tu Z, Xiao C, Yan S, Ma X, Guo X, Chen X, Yin P, Yang Z, Yang S, Jiang T, Li S, Qin C, Li XJ. CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys. Cell Research. PMID 30770867 DOI: 10.1038/S41422-019-0142-Y  0.334
2019 Huang S, Zhu S, Li XJ, Li S. The Expanding Clinical Universe of Polyglutamine Disease. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858418822993. PMID 30614396 DOI: 10.1177/1073858418822993  0.393
2018 Li T, Li S, Gao X, Cai Q, Li XJ. Expression and Localization of Huntingtin-Associated Protein 1 (HAP1) in the Human Digestive System. Digestive Diseases and Sciences. PMID 30560333 DOI: 10.1007/S10620-018-5425-5  0.459
2018 Yang S, Li S, Li XJ. MANF: A New Player in the Control of Energy Homeostasis, and Beyond. Frontiers in Physiology. 9: 1725. PMID 30555354 DOI: 10.3389/Fphys.2018.01725  0.369
2018 Yang S, Li S, Li XJ. Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity. Cell Reports. 25: 2653-2659.e3. PMID 30517854 DOI: 10.1016/J.Celrep.2018.11.019  0.386
2018 Tu Z, Zhao H, Li B, Yan S, Wang L, Tang Y, Li Z, Bai D, Li C, Lin Y, Li Y, Liu J, Xu H, Guo X, Jiang YH, ... ... Li XJ, et al. CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms. Human Molecular Genetics. PMID 30329048 DOI: 10.1093/Hmg/Ddy367  0.341
2018 Yan S, Tu Z, Liu Z, Fan N, Yang H, Yang S, Yang W, Zhao Y, Ouyang Z, Lai C, Yang H, Li L, Liu Q, Shi H, Xu G, ... ... Li XJ, et al. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. Cell. PMID 29606351 DOI: 10.1016/J.Cell.2018.03.005  0.473
2018 Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, Tang B, Jin P, Li XJ, Yang S, Li S. Piperine ameliorates SCA17 neuropathology by reducing ER stress. Molecular Neurodegeneration. 13: 4. PMID 29378605 DOI: 10.1186/S13024-018-0236-X  0.46
2017 Yang S, Yang H, Chang R, Yin P, Yang Y, Yang W, Huang S, Gaertig MA, Li S, Li XJ. MANF regulates hypothalamic control of food intake and body weight. Nature Communications. 8: 579. PMID 28924165 DOI: 10.1038/S41467-017-00750-X  0.316
2017 Hong Y, Zhao T, Li XJ, Li S. Mutant huntingtin inhibits αB-crystallin expression and impairs exosome secretion from astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28893927 DOI: 10.1523/Jneurosci.1418-17.2017  0.506
2017 Zhao T, Hong Y, Yin P, Li S, Li XJ. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847953 DOI: 10.1073/Pnas.1710549114  0.507
2017 Yang Y, Yang S, Guo J, Cui Y, Tang B, Li XJ, Li S. Synergistic toxicity of polyglutamine-expanded TBP in glia and neuronal cells: therapeutic implications for SCA17. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28821675 DOI: 10.1523/Jneurosci.0111-17.2017  0.512
2017 Zhao H, Tu Z, Xu H, Yan S, Yan H, Zheng Y, Yang W, Zheng J, Li Z, Tian R, Lu Y, Guo X, Jiang YH, Li XJ, Zhang YQ. Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate. Cell Research. PMID 28741620 DOI: 10.1038/Cr.2017.95  0.312
2017 Yang S, Chang R, Yang H, Zhao T, Hong Y, Kong HE, Sun X, Qin Z, Jin P, Li S, Li XJ. CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease. The Journal of Clinical Investigation. PMID 28628038 DOI: 10.1172/Jci92087  0.492
2017 Yan S, Tu Z, Li S, Li XJ. Use of CRISPR/Cas9 to model brain diseases. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28392484 DOI: 10.1016/J.Pnpbp.2017.04.003  0.374
2017 Xiang J, Yang S, Xin N, Gaertig MA, Reeves RH, Li S, Li XJ. DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137862 DOI: 10.1073/Pnas.1614893114  0.341
2017 Lim Y, Wu LL, Chen S, Sun Y, Vijayaraj SL, Yang M, Bobrovskaya L, Keating D, Li XJ, Zhou XF. HAP1 Is Required for Endocytosis and Signalling of BDNF and Its Receptors in Neurons. Molecular Neurobiology. PMID 28083816 DOI: 10.1007/S12035-016-0379-0  0.385
2016 Cui Y, Yang S, Li XJ, Li S. Genetically modified rodent models of SCA17. Journal of Neuroscience Research. PMID 27859490 DOI: 10.1002/Jnr.23984  0.41
2016 Hong Y, Zhao T, Li XJ, Li S. Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8790-801. PMID 27559163 DOI: 10.1523/Jneurosci.0168-16.2016  0.422
2016 Zhao T, Hong Y, Li S, Li XJ. Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8317-28. PMID 27511006 DOI: 10.1523/Jneurosci.0806-16.2016  0.531
2016 Liu X, Wang CE, Hong Y, Zhao T, Wang G, Gaertig MA, Sun M, Li S, Li XJ. N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy. Plos Genetics. 12: e1006083. PMID 27203582 DOI: 10.1371/Journal.Pgen.1006083  0.513
2016 Yang W, Tu Z, Sun Q, Li XJ. CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases. Frontiers in Molecular Neuroscience. 9: 30. PMID 27199655 DOI: 10.3389/Fnmol.2016.00030  0.339
2016 Zhao T, Hong Y, Li XJ, Li SH. Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-Review. Frontiers in Molecular Neuroscience. 9: 27. PMID 27147961 DOI: 10.3389/Fnmol.2016.00027  0.528
2016 Wang G, Liu X, Gaertig MA, Li S, Li XJ. Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26951659 DOI: 10.1073/Pnas.1524575113  0.449
2015 Huang S, Yang S, Guo J, Yan S, Gaertig MA, Li S, Li XJ. Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice. Cell Reports. PMID 26387956 DOI: 10.1016/J.Celrep.2015.08.060  0.388
2015 Wang G, Yang H, Yan S, Wang CE, Liu X, Zhao B, Ouyang Z, Yin P, Liu Z, Zhao Y, Liu T, Fan N, Guo L, Li S, Li XJ, et al. Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain. Molecular Neurodegeneration. 10: 42. PMID 26334913 DOI: 10.1186/S13024-015-0036-5  0.461
2015 Tu Z, Yang W, Yan S, Guo X, Li XJ. CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases. Molecular Neurodegeneration. 10: 35. PMID 26238861 DOI: 10.1186/S13024-015-0031-X  0.315
2015 Jiang W, Wei W, Gaertig MA, Li S, Li XJ. Therapeutic Effect of Berberine on Huntington's Disease Transgenic Mouse Model. Plos One. 10: e0134142. PMID 26225560 DOI: 10.1371/Journal.Pone.0134142  0.505
2015 Yang W, Wang G, Wang CE, Guo X, Yin P, Gao J, Tu Z, Wang Z, Wu J, Hu X, Li S, Li XJ. Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8345-58. PMID 26019347 DOI: 10.1523/Jneurosci.0772-15.2015  0.364
2015 Chan AW, Jiang J, Chen Y, Li C, Prucha MS, Hu Y, Chi T, Moran S, Rahim T, Li S, Li X, Zola SM, Testa CM, Mao H, Villalba R, et al. Progressive cognitive deficit, motor impairment and striatal pathology in a transgenic Huntington disease monkey model from infancy to adulthood. Plos One. 10: e0122335. PMID 25966278 DOI: 10.1371/Journal.Pone.0122335  0.396
2015 Chang R, Liu X, Li S, Li XJ. Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy. Drug Design, Development and Therapy. 9: 2179-88. PMID 25931812 DOI: 10.2147/Dddt.S58470  0.485
2015 Xiang J, Yan S, Li SH, Li XJ. Postnatal loss of hap1 reduces hippocampal neurogenesis and causes adult depressive-like behavior in mice. Plos Genetics. 11: e1005175. PMID 25875952 DOI: 10.1371/Journal.Pgen.1005175  0.351
2015 Huang B, Wei W, Wang G, Gaertig MA, Feng Y, Wang W, Li XJ, Li S. Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes. Neuron. 85: 1212-26. PMID 25789755 DOI: 10.1016/J.Neuron.2015.02.026  0.437
2015 Jiang W, Li SH, Li X. Therapeutic potential of berberine against neurodegenerative diseases Science China-Life Sciences. 58: 564-569. PMID 25749423 DOI: 10.1007/S11427-015-4829-0  0.339
2015 Yin P, Tu Z, Yin A, Zhao T, Yan S, Guo X, Chang R, Zhang L, Hong Y, Huang X, Zhou J, Wang Y, Li S, Li XJ. Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin. Human Molecular Genetics. 24: 1350-62. PMID 25343992 DOI: 10.1093/Hmg/Ddu544  0.452
2015 Li XJ, Li S. Large Animal Models of Huntington's Disease. Current Topics in Behavioral Neurosciences. 22: 149-60. PMID 24048953 DOI: 10.1007/7854_2013_246  0.489
2014 Wade BE, Wang CE, Yan S, Bhat K, Huang B, Li S, Li XJ. Ubiquitin-activating enzyme activity contributes to differential accumulation of mutant huntingtin in brain and peripheral tissues. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8411-22. PMID 24948797 DOI: 10.1523/Jneurosci.0775-14.2014  0.818
2014 Bhat KP, Yan S, Wang CE, Li S, Li XJ. Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A. Proceedings of the National Academy of Sciences of the United States of America. 111: 5706-11. PMID 24706802 DOI: 10.1073/Pnas.1402215111  0.437
2014 Yang S, Huang S, Gaertig MA, Li XJ, Li S. Age-dependent decrease in chaperone activity impairs MANF expression, leading to Purkinje cell degeneration in inducible SCA17 mice. Neuron. 81: 349-65. PMID 24462098 DOI: 10.1016/J.Neuron.2013.12.002  0.493
2014 Yan S, Wang CE, Wei W, Gaertig MA, Lai L, Li S, Li XJ. TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain. Human Molecular Genetics. 23: 2678-93. PMID 24381309 DOI: 10.1093/Hmg/Ddt662  0.516
2014 Xiang J, Yang H, Zhao T, Sun M, Xu X, Zhou XF, Li SH, Li XJ. Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting. The Journal of Clinical Investigation. 124: 85-98. PMID 24355921 DOI: 10.1172/Jci69206  0.47
2013 Xu Q, Huang S, Song M, Wang CE, Yan S, Liu X, Gaertig MA, Yu SP, Li H, Li S, Li XJ. Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms. The Journal of Cell Biology. 202: 1123-38. PMID 24081492 DOI: 10.1083/Jcb.201303146  0.454
2013 Weng L, Lin YF, Li AL, Wang CE, Yan S, Sun M, Gaertig MA, Mitha N, Kosaka J, Wakabayashi T, Xu X, Tang B, Li S, Li XJ. Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8172-84. PMID 23658157 DOI: 10.1523/Jneurosci.0119-13.2013  0.398
2012 Li XJ, Li S. Influence of species differences on the neuropathology of transgenic Huntington's disease animal models. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 39: 239-45. PMID 22749010 DOI: 10.1016/J.Jgg.2012.05.002  0.46
2012 Li XJ, Li W. Beyond mice: genetically modifying larger animals to model human diseases. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 39: 237-8. PMID 22749009 DOI: 10.1016/J.Jgg.2012.05.006  0.337
2012 Li S, Li XJ. A huntingtin-HAP1-PCM1 pathway in ciliogenesis. Expert Review of Proteomics. 9: 17-9. PMID 22292820 DOI: 10.1586/Epr.11.72  0.469
2012 Cape A, Chen X, Wang CE, O'Neill A, Lin YF, He J, Xu XS, Yi H, Li H, Li S, Li XJ. Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells. Cellular and Molecular Life Sciences : Cmls. 69: 1305-17. PMID 21544547 DOI: 10.1007/S00018-011-0692-8  0.774
2012 Li X, Li S. Neuropathology of transgenic HD animal models Molecular Neurodegeneration. 7: 1-1. DOI: 10.1186/1750-1326-7-S1-L17  0.416
2011 Mandal M, Wei J, Zhong P, Cheng J, Duffney LJ, Liu W, Yuen EY, Twelvetrees AE, Li S, Li XJ, Kittler JT, Yan Z. Impaired alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking and function by mutant huntingtin. The Journal of Biological Chemistry. 286: 33719-28. PMID 21832090 DOI: 10.1074/Jbc.M111.236521  0.448
2011 Huang S, Ling JJ, Yang S, Li XJ, Li S. Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor. Brain : a Journal of Neurology. 134: 1943-58. PMID 21705419 DOI: 10.1093/Brain/Awr146  0.549
2011 Yang M, Lim Y, Li X, Zhong J, Zhou X. Precursor of Brain-derived Neurotrophic Factor (proBDNF) Forms a Complex with Huntingtin-associated Protein-1 (HAP1) and Sortilin That Modulates proBDNF Trafficking, Degradation, and Processing Journal of Biological Chemistry. 286: 16272-16284. PMID 21357693 DOI: 10.1074/Jbc.M110.195347  0.452
2011 Havel LS, Wang CE, Wade B, Huang B, Li S, Li XJ. Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation. Human Molecular Genetics. 20: 1424-37. PMID 21245084 DOI: 10.1093/Hmg/Ddr023  0.819
2011 Li XJ, Li S. Proteasomal dysfunction in aging and Huntington disease. Neurobiology of Disease. 43: 4-8. PMID 21145396 DOI: 10.1016/J.Nbd.2010.11.018  0.491
2010 Wang CE, Li S, Li XJ. Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice. Molecular Brain. 3: 33. PMID 21044321 DOI: 10.1186/1756-6606-3-33  0.423
2010 Xu X, Yang H, Lin YF, Li X, Cape A, Ressler KJ, Li S, Li XJ. Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype. Proceedings of the National Academy of Sciences of the United States of America. 107: 19126-31. PMID 20956301 DOI: 10.1073/Pnas.1013032107  0.794
2010 Yang D, Wang CE, Zhao B, Li W, Ouyang Z, Liu Z, Yang H, Fan P, O'Neill A, Gu W, Yi H, Li S, Lai L, Li XJ. Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs. Human Molecular Genetics. 19: 3983-94. PMID 20660116 DOI: 10.1093/hmg/ddq313  0.445
2010 Li XJ, Li H, Li S. Clearance of mutant huntingtin. Autophagy. 6: 663-4. PMID 20519964 DOI: 10.4161/Auto.6.5.12336  0.505
2010 Li X, Wang CE, Huang S, Xu X, Li XJ, Li H, Li S. Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments. Human Molecular Genetics. 19: 2445-55. PMID 20354076 DOI: 10.1093/Hmg/Ddq127  0.519
2010 Lin YF, Xu X, Cape A, Li S, Li XJ. Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice. The Journal of Biological Chemistry. 285: 15941-9. PMID 20304926 DOI: 10.1074/Jbc.M110.107318  0.82
2010 Bradford JW, Li S, Li XJ. Polyglutamine toxicity in non-neuronal cells. Cell Research. 20: 400-7. PMID 20231860 DOI: 10.1038/cr.2010.32  0.409
2010 Bradford J, Shin JY, Roberts M, Wang CE, Sheng G, Li S, Li XJ. Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice. The Journal of Biological Chemistry. 285: 10653-61. PMID 20145253 DOI: 10.1074/jbc.M109.083287  0.695
2010 Wu LL, Fan Y, Li S, Li XJ, Zhou XF. Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release. The Journal of Biological Chemistry. 285: 5614-23. PMID 19996106 DOI: 10.1074/Jbc.M109.073197  0.357
2010 Li XJ, Orr AL, Li S. Impaired mitochondrial trafficking in Huntington's disease. Biochimica Et Biophysica Acta. 1802: 62-5. PMID 19591925 DOI: 10.1016/J.Bbadis.2009.06.008  0.73
2009 Bradford J, Shin JY, Roberts M, Wang CE, Li XJ, Li S. Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms. Proceedings of the National Academy of Sciences of the United States of America. 106: 22480-5. PMID 20018729 DOI: 10.1073/pnas.0911503106  0.708
2009 Friedman MJ, Li S, Li XJ. Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection. The Journal of Biological Chemistry. 284: 27944-51. PMID 19656944 DOI: 10.1074/Jbc.M109.037937  0.809
2009 Shah AG, Friedman MJ, Huang S, Roberts M, Li XJ, Li S. Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17. Human Molecular Genetics. 18: 4141-52. PMID 19643914 DOI: 10.1093/Hmg/Ddp363  0.839
2009 Havel LS, Li S, Li XJ. Nuclear accumulation of polyglutamine disease proteins and neuropathology. Molecular Brain. 2: 21. PMID 19575804 DOI: 10.1186/1756-6606-2-21  0.803
2009 Orr AG, Orr AL, Li XJ, Gross RE, Traynelis SF. Adenosine A(2A) receptor mediates microglial process retraction. Nature Neuroscience. 12: 872-8. PMID 19525944 DOI: 10.1038/Nn.2341  0.678
2008 Tydlacka S, Wang CE, Wang X, Li S, Li XJ. Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13285-95. PMID 19052220 DOI: 10.1523/Jneurosci.4393-08.2008  0.815
2008 Zhou LL, Zhao Y, Ringrose A, DeGeer D, Kennah E, Lin AE, Sheng G, Li XJ, Turhan A, Jiang X. AHI-1 interacts with BCR-ABL and modulates BCR-ABL transforming activity and imatinib response of CML stem/progenitor cells. The Journal of Experimental Medicine. 205: 2657-71. PMID 18936234 DOI: 10.1084/Jem.20072316  0.308
2008 Li X, Li H, Li XJ. Intracellular degradation of misfolded proteins in polyglutamine neurodegenerative diseases. Brain Research Reviews. 59: 245-52. PMID 18773920 DOI: 10.1016/J.Brainresrev.2008.08.003  0.491
2008 Sheng G, Xu X, Lin YF, Wang CE, Rong J, Cheng D, Peng J, Jiang X, Li SH, Li XJ. Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. The Journal of Clinical Investigation. 118: 2785-95. PMID 18636121 DOI: 10.1172/Jci35339  0.771
2008 Wang CE, Tydlacka S, Orr AL, Yang SH, Graham RK, Hayden MR, Li S, Chan AW, Li XJ. Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease. Human Molecular Genetics. 17: 2738-51. PMID 18558632 DOI: 10.1093/Hmg/Ddn175  0.813
2008 Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6182-95. PMID 18550760 DOI: 10.1523/Jneurosci.0857-08.2008  0.489
2008 Wang CE, Zhou H, McGuire JR, Cerullo V, Lee B, Li SH, Li XJ. Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin. The Journal of Cell Biology. 181: 803-16. PMID 18504298 DOI: 10.1083/Jcb.200710158  0.505
2008 Orr AL, Huang S, Roberts MA, Reed JC, Li S, Li XJ. Sex-dependent effect of BAG1 in ameliorating motor deficits of Huntington disease transgenic mice. The Journal of Biological Chemistry. 283: 16027-36. PMID 18400759 DOI: 10.1074/Jbc.M710606200  0.757
2008 Liu Z, Jang SW, Liu X, Cheng D, Peng J, Yepes M, Li XJ, Matthews S, Watts C, Asano M, Hara-Nishimura I, Luo HR, Ye K. Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. Molecular Cell. 29: 665-78. PMID 18374643 DOI: 10.1016/J.Molcel.2008.02.017  0.379
2008 Wang J, Wang CE, Orr A, Tydlacka S, Li SH, Li XJ. Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice. The Journal of Cell Biology. 180: 1177-89. PMID 18362179 DOI: 10.1083/Jcb.200709080  0.794
2008 Orr AL, Li S, Wang CE, Li H, Wang J, Rong J, Xu X, Mastroberardino PG, Greenamyre JT, Li XJ. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2783-92. PMID 18337408 DOI: 10.1523/Jneurosci.0106-08.2008  0.825
2008 Friedman MJ, Wang CE, Li XJ, Li S. Polyglutamine expansion reduces the association of TATA-binding protein with DNA and induces DNA binding-independent neurotoxicity. The Journal of Biological Chemistry. 283: 8283-90. PMID 18218637 DOI: 10.1074/Jbc.M709674200  0.793
2008 Metzger S, Rong J, Nguyen HP, Cape A, Tomiuk J, Soehn AS, Propping P, Freudenberg-Hua Y, Freudenberg J, Tong L, Li SH, Li XJ, Riess O. Huntingtin-associated protein-1 is a modifier of the age-at-onset of Huntington's disease. Human Molecular Genetics. 17: 1137-46. PMID 18192679 DOI: 10.1093/Hmg/Ddn003  0.775
2007 Friedman MJ, Shah AG, Fang ZH, Ward EG, Warren ST, Li S, Li XJ. Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration. Nature Neuroscience. 10: 1519-28. PMID 17994014 DOI: 10.1038/Nn2011  0.821
2007 Li XJ, Friedman M, Li S. Interacting proteins as genetic modifiers of Huntington disease. Trends in Genetics : Tig. 23: 531-3. PMID 17961788 DOI: 10.1016/J.Tig.2007.07.007  0.808
2007 Rong J, Li SH, Li XJ. Regulation of intracellular HAP1 trafficking. Journal of Neuroscience Research. 85: 3025-9. PMID 17474105 DOI: 10.1002/Jnr.21326  0.798
2007 Gu X, André VM, Cepeda C, Li SH, Li XJ, Levine MS, Yang XW. Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease. Molecular Neurodegeneration. 2: 8. PMID 17470275 DOI: 10.1186/1750-1326-2-8  0.469
2007 Rong J, Li S, Sheng G, Wu M, Coblitz B, Li M, Fu H, Li XJ. 14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking. The Journal of Biological Chemistry. 282: 4748-56. PMID 17166838 DOI: 10.1074/Jbc.M609057200  0.761
2007 Zhang X, Winkles JA, Gongora MC, Polavarapu R, Michaelson JS, Hahm K, Burkly L, Friedman M, Li XJ, Yepes M. TWEAK-Fn14 pathway inhibition protects the integrity of the neurovascular unit during cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 534-44. PMID 16835630 DOI: 10.1038/Sj.Jcbfm.9600368  0.77
2007 Zhao Y, Zhou L, Ringrose A, Lin AE, Kennah E, Sheng G, Li X, Turhan A, Jiang X. Interaction of a Novel Signaling Protein (AHI-1) with BCR-ABL Modulates BCR-ABL Transforming Activity and Imatinib Response of Chronic Myeloid Leukemia Progenitor Cells. Blood. 110: 467-467. DOI: 10.1182/Blood.V110.11.467.467  0.361
2007 Pastorino L, Sun A, Lu PJ, Zhou XZ, Balastik M, Finn G, Wulf G, Lim J, Li SH, Li X, Xia W, Nicholson LK, Lu KP. Erratum: The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-Β production (Nature (2006) 440, (528-534)) Nature. 446. DOI: 10.1038/Nature05606  0.304
2006 Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, ... ... Li XJ, et al. Recent advances in basic neurosciences and brain disease: from synapses to behavior. Molecular Pain. 2: 38. PMID 17196111 DOI: 10.1186/1744-8069-2-38  0.355
2006 Li S, Li XJ. Multiple pathways contribute to the pathogenesis of Huntington disease. Molecular Neurodegeneration. 1: 19. PMID 17173700 DOI: 10.1186/1750-1326-1-19  0.516
2006 Cornett J, Smith L, Friedman M, Shin JY, Li XJ, Li SH. Context-dependent dysregulation of transcription by mutant huntingtin. The Journal of Biological Chemistry. 281: 36198-204. PMID 17012230 DOI: 10.1074/Jbc.M607839200  0.811
2006 Rong J, McGuire JR, Fang ZH, Sheng G, Shin JY, Li SH, Li XJ. Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6019-30. PMID 16738245 DOI: 10.1523/Jneurosci.1251-06.2006  0.813
2006 Sheng G, Chang GQ, Lin JY, Yu ZX, Fang ZH, Rong J, Lipton SA, Li SH, Tong G, Leibowitz SF, Li XJ. Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior. Nature Medicine. 12: 526-33. PMID 16604089 DOI: 10.1038/Nm1382  0.736
2006 Pastorino L, Sun A, Lu PJ, Zhou XZ, Balastik M, Finn G, Wulf G, Lim J, Li SH, Li X, Xia W, Nicholson LK, Lu KP. The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. Nature. 440: 528-34. PMID 16554819 DOI: 10.1038/Nature04543  0.391
2006 Bae BI, Hara MR, Cascio MB, Wellington CL, Hayden MR, Ross CA, Ha HC, Li XJ, Snyder SH, Sawa A. Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH. Proceedings of the National Academy of Sciences of the United States of America. 103: 3405-9. PMID 16492755 DOI: 10.1073/Pnas.0511316103  0.327
2006 McGuire JR, Rong J, Li SH, Li XJ. Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons. The Journal of Biological Chemistry. 281: 3552-9. PMID 16339760 DOI: 10.1074/Jbc.M509806200  0.789
2006 Shin J, Fang Z, Yu Z, Wang C, Li S, Li X. Correction: Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity Journal of Cell Biology. 172: 953-953. DOI: 10.1083/Jcb.20050807220060228C  0.687
2005 Shin JY, Fang ZH, Yu ZX, Wang CE, Li SH, Li XJ. Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity. The Journal of Cell Biology. 171: 1001-12. PMID 16365166 DOI: 10.1083/Jcb.200508072  0.711
2005 Benn CL, Landles C, Li H, Strand AD, Woodman B, Sathasivam K, Li SH, Ghazi-Noori S, Hockly E, Faruque SM, Cha JH, Sharpe PT, Olson JM, Li XJ, Bates GP. Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease. Human Molecular Genetics. 14: 3065-78. PMID 16183657 DOI: 10.1093/Hmg/Ddi340  0.412
2005 Liao M, Shen J, Zhang Y, Li SH, Li XJ, Li H. Immunohistochemical localization of huntingtin-associated protein 1 in endocrine system of the rat. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 1517-24. PMID 16087704 DOI: 10.1369/Jhc.5A6662.2005  0.359
2005 Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron. 46: 433-44. PMID 15882643 DOI: 10.1016/J.Neuron.2005.03.025  0.491
2005 Cornett J, Cao F, Wang CE, Ross CA, Bates GP, Li SH, Li XJ. Polyglutamine expansion of huntingtin impairs its nuclear export. Nature Genetics. 37: 198-204. PMID 15654337 DOI: 10.1038/Ng1503  0.36
2005 Li XJ, Li SH. HAP1 and intracellular trafficking. Trends in Pharmacological Sciences. 26: 1-3. PMID 15629196 DOI: 10.1016/J.Tips.2004.11.001  0.421
2005 Cornett J, Friedman M, Li SH, Li XJ. Transcriptional dysregulation: A therapeutic target for polyglutamine diseases Current Medicinal Chemistry - Central Nervous System Agents. 5: 119-127. DOI: 10.2174/1568015054022399  0.773
2005 McGuire J, Li S, Li X. Polyglutamine Protein Trafficking and Neurodegeneration Current Genomics. 6: 189-194. DOI: 10.2174/1389202053971938  0.371
2005 Ringrose A, Zhou Y, Pang E, Lin AE, Li X, Li I, Weng A, Jiang X. Stable Suppression of a Novel Oncogene, AHI-1, in Human Cutaneous T-Cell Leukemia Cells Normalizes Its Transforming Activity In Vitro and In Vivo and Aberrant Expression of AHI-1 Is Also Present in Leukemic Sezary Cells from Patients with Sezary Syndrome. Blood. 106: 2605-2605. DOI: 10.1182/Blood.V106.11.2605.2605  0.314
2004 Li SH, Li XJ. Huntingtin and its role in neuronal degeneration. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10: 467-75. PMID 15359012 DOI: 10.1177/1073858404266777  0.46
2004 Li SH, Li XJ. Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends in Genetics : Tig. 20: 146-54. PMID 15036808 DOI: 10.1016/J.Tig.2004.01.008  0.432
2003 Zhou H, Cao F, Wang Z, Yu ZX, Nguyen HP, Evans J, Li SH, Li XJ. Huntingtin forms toxic NH2-terminal fragment complexes that are promoted by the age-dependent decrease in proteasome activity. The Journal of Cell Biology. 163: 109-18. PMID 14557250 DOI: 10.1083/Jcb.200306038  0.489
2003 Li H, Wyman T, Yu ZX, Li SH, Li XJ. Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release. Human Molecular Genetics. 12: 2021-30. PMID 12913073 DOI: 10.1093/Hmg/Ddg218  0.401
2003 Liou YC, Sun A, Ryo A, Zhou XZ, Yu ZX, Huang HK, Uchida T, Bronson R, Bing G, Li X, Hunter T, Lu KP. Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. Nature. 424: 556-61. PMID 12891359 DOI: 10.1038/Nature01832  0.456
2003 Li SH, Yu ZX, Li CL, Nguyen HP, Zhou YX, Deng C, Li XJ. Lack of huntingtin-associated protein-1 causes neuronal death resembling hypothalamic degeneration in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6956-64. PMID 12890790 DOI: 10.1523/JNEUROSCI.23-17-06956.2003  0.41
2003 Slow EJ, van Raamsdonk J, Rogers D, Coleman SH, Graham RK, Deng Y, Oh R, Bissada N, Hossain SM, Yang YZ, Li XJ, Simpson EM, Gutekunst CA, Leavitt BR, Hayden MR. Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Human Molecular Genetics. 12: 1555-67. PMID 12812983 DOI: 10.1093/Hmg/Ddg169  0.453
2003 Yu ZX, Li SH, Evans J, Pillarisetti A, Li H, Li XJ. Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2193-202. PMID 12657678 DOI: 10.1523/Jneurosci.23-06-02193.2003  0.54
2003 von Hörsten S, Schmitt I, Nguyen HP, Holzmann C, Schmidt T, Walther T, Bader M, Pabst R, Kobbe P, Krotova J, Stiller D, Kask A, Vaarmann A, Rathke-Hartlieb S, Schulz JB, ... ... Li XJ, et al. Transgenic rat model of Huntington's disease. Human Molecular Genetics. 12: 617-24. PMID 12620967 DOI: 10.1093/Hmg/Ddg075  0.414
2003 Duan W, Guo Z, Jiang H, Ware M, Li XJ, Mattson MP. Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 2911-6. PMID 12589027 DOI: 10.1073/Pnas.0536856100  0.386
2002 Menalled LB, Sison JD, Wu Y, Olivieri M, Li XJ, Li H, Zeitlin S, Chesselet MF. Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8266-76. PMID 12223581 DOI: 10.1523/Jneurosci.22-18-08266.2002  0.447
2002 Yu ZX, Li SH, Nguyen HP, Li XJ. Huntingtin inclusions do not deplete polyglutamine-containing transcription factors in HD mice. Human Molecular Genetics. 11: 905-14. PMID 11971872 DOI: 10.1093/Hmg/11.8.905  0.455
2002 Chuang JZ, Zhou H, Zhu M, Li SH, Li XJ, Sung CH. Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independently. The Journal of Biological Chemistry. 277: 19831-8. PMID 11896048 DOI: 10.1074/Jbc.M109613200  0.405
2002 Li SH, Cheng AL, Zhou H, Lam S, Rao M, Li H, Li XJ. Interaction of Huntington disease protein with transcriptional activator Sp1. Molecular and Cellular Biology. 22: 1277-87. PMID 11839795 DOI: 10.1128/Mcb.22.5.1277-1287.2002  0.455
2001 Zhou H, Li S, Li X. Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation. Journal of Biological Chemistry. 276: 48417-48424. PMID 11606565 DOI: 10.1074/Jbc.M104140200  0.414
2001 Cao F, Levine JJ, Li SH, Li XJ. Nuclear aggregation of huntingtin is not prevented by deletion of chaperone Hsp104. Biochimica Et Biophysica Acta. 1537: 158-66. PMID 11566259 DOI: 10.1016/S0925-4439(01)00068-0  0.405
2001 Schilling G, Jinnah HA, Gonzales V, Coonfield ML, Kim Y, Wood JD, Price DL, Li XJ, Jenkins N, Copeland N, Moran T, Ross CA, Borchelt DR. Distinct behavioral and neuropathological abnormalities in transgenic mouse models of HD and DRPLA. Neurobiology of Disease. 8: 405-18. PMID 11442350 DOI: 10.1006/Nbdi.2001.0385  0.508
2001 Li H, Li S, Yu Z, Shelbourne P, Li X. Huntingtin Aggregate-Associated Axonal Degeneration is an Early Pathological Event in Huntington's Disease Mice The Journal of Neuroscience. 21: 8473-8481. DOI: 10.1523/Jneurosci.21-21-08473.2001  0.454
2000 Freeman TB, Cicchetti F, Hauser RA, Deacon TW, Li XJ, Hersch SM, Nauert GM, Sanberg PR, Kordower JH, Saporta S, Isacson O. Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology. Proceedings of the National Academy of Sciences of the United States of America. 97: 13877-82. PMID 11106399 DOI: 10.1073/Pnas.97.25.13877  0.405
2000 Li S, Lam S, Cheng AL, Li X. Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis Human Molecular Genetics. 9: 2859-2867. PMID 11092762 DOI: 10.1093/Hmg/9.19.2859  0.393
2000 Li XJ. The early cellular pathology of Huntington's disease. Molecular Neurobiology. 20: 111-24. PMID 10966117 DOI: 10.1007/Bf02742437  0.539
2000 Li H, Li SH, Johnston H, Shelbourne PF, Li XJ. Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity. Nature Genetics. 25: 385-9. PMID 10932179 DOI: 10.1038/78054  0.511
2000 Li SH, Li H, Torre ER, Li XJ. Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth. Molecular and Cellular Neurosciences. 16: 168-83. PMID 10924259 DOI: 10.1006/Mcne.2000.0858  0.478
1999 Kuemmerle S, Gutekunst CA, Klein AM, Li XJ, Li SH, Beal MF, Hersch SM, Ferrante RJ. Huntington aggregates may not predict neuronal death in Huntington's disease. Annals of Neurology. 46: 842-9. PMID 10589536 DOI: 10.1002/1531-8249(199912)46:6<842::Aid-Ana6>3.0.Co;2-O  0.461
1999 Hodgson JG, Agopyan N, Gutekunst CA, Leavitt BR, LePiane F, Singaraja R, Smith DJ, Bissada N, McCutcheon K, Nasir J, Jamot L, Li XJ, Stevens ME, Rosemond E, Roder JC, et al. A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron. 23: 181-92. PMID 10402204 DOI: 10.1016/S0896-6273(00)80764-3  0.531
1999 Li H, Li SH, Cheng AL, Mangiarini L, Bates GP, Li XJ. Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice. Human Molecular Genetics. 8: 1227-36. PMID 10369868 DOI: 10.1093/Hmg/8.7.1227  0.445
1999 Ona VO, Li M, Vonsattel JP, Andrews LJ, Khan SQ, Chung WM, Frey AS, Menon AS, Li XJ, Stieg PE, Yuan J, Penney JB, Young AB, Cha JH, Friedlander RM. Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature. 399: 263-7. PMID 10353249 DOI: 10.1038/20446  0.47
1999 Gutekunst CA, Li SH, Yi H, Mulroy JS, Kuemmerle S, Jones R, Rye D, Ferrante RJ, Hersch SM, Li XJ. Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2522-34. PMID 10087066 DOI: 10.1523/Jneurosci.19-07-02522.1999  0.455
1999 Li S, Cheng AL, Li H, Li X. Cellular Defects and Altered Gene Expression in PC12 Cells Stably Expressing Mutant Huntingtin The Journal of Neuroscience. 19: 5159-5172. DOI: 10.1523/Jneurosci.19-13-05159.1999  0.398
1998 Li SH, Gutekunst CA, Hersch SM, Li XJ. Association of HAP1 isoforms with a unique cytoplasmic structure. Journal of Neurochemistry. 71: 2178-85. PMID 9798945 DOI: 10.1046/J.1471-4159.1998.71052178.X  0.38
1998 Gutekunst CA, Li SH, Yi H, Ferrante RJ, Li XJ, Hersch SM. The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7674-86. PMID 9742138 DOI: 10.1523/Jneurosci.18-19-07674.1998  0.427
1998 Li SH, Hosseini SH, Gutekunst CA, Hersch SM, Ferrante RJ, Li XJ. A human HAP1 homologue. Cloning, expression, and interaction with huntingtin. The Journal of Biological Chemistry. 273: 19220-7. PMID 9668110 DOI: 10.1074/Jbc.273.30.19220  0.42
1998 Li S, Li X. Aggregation of N-Terminal Huntingtin is Dependent on the Length of Its Glutamine Repeats Human Molecular Genetics. 7: 777-782. PMID 9536080 DOI: 10.1093/Hmg/7.5.777  0.467
1998 Li SH, Gutekunst CA, Hersch SM, Li XJ. Interaction of huntingtin-associated protein with dynactin P150Glued. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1261-9. PMID 9454836 DOI: 10.1523/Jneurosci.18-04-01261.1998  0.419
1998 Reddy TR, Li X, Jones Y, Ellisman MH, Ching GY, Liem RK, Wong-Staal F. Specific interaction of HTLV tax protein and a human type IV neuronal intermediate filament protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 702-7. PMID 9435256 DOI: 10.1073/Pnas.95.2.702  0.308
1995 Sharp AH, Loev SJ, Schilling G, Li SH, Li XJ, Bao J, Wagster MV, Kotzuk JA, Steiner JP, Lo A. Widespread expression of Huntington's disease gene (IT15) protein product. Neuron. 14: 1065-74. PMID 7748554 DOI: 10.1016/0896-6273(95)90345-3  0.379
1995 Li XJ, Snyder SH. Molecular cloning of Ebnerin, a von Ebner's gland protein associated with taste buds. The Journal of Biological Chemistry. 270: 17674-9. PMID 7629065 DOI: 10.1074/Jbc.270.30.17674  0.346
1995 Li XJ, Li SH, Sharp AH, Nucifora FC, Schilling G, Lanahan A, Worley P, Snyder SH, Ross CA. A huntingtin-associated protein enriched in brain with implications for pathology. Nature. 378: 398-402. PMID 7477378 DOI: 10.1038/378398A0  0.367
Low-probability matches (unlikely to be authored by this person)
2008 Yang SH, Cheng PH, Banta H, Piotrowska-Nitsche K, Yang JJ, Cheng EC, Snyder B, Larkin K, Liu J, Orkin J, Fang ZH, Smith Y, Bachevalier J, Zola SM, Li SH, ... Li XJ, et al. Towards a transgenic model of Huntington's disease in a non-human primate. Nature. 453: 921-4. PMID 18488016 DOI: 10.1038/Nature06975  0.297
2016 Yang S, Li XJ, Li S. Molecular mechanisms underlying Spinocerebellar Ataxia 17 (SCA17) pathogenesis. Rare Diseases (Austin, Tex.). 4: e1223580. PMID 28032013 DOI: 10.1080/21675511.2016.1223580  0.295
2011 Niu SN, Huang ZB, Wang H, Rao XR, Kong H, Xu J, Li XJ, Yang C, Sheng GQ. Brainstem Hap1-Ahi1 is involved in insulin-mediated feeding control. Febs Letters. 585: 85-91. PMID 21146532 DOI: 10.1016/J.Febslet.2010.11.059  0.293
2019 Zhao H, Wang Q, Yan T, Zhang Y, Xu HJ, Yu HP, Tu Z, Guo X, Jiang YH, Li XJ, Zhou H, Zhang YQ. Maternal valproic acid exposure leads to neurogenesis defects and autism-like behaviors in non-human primates. Translational Psychiatry. 9: 267. PMID 31636273 DOI: 10.1038/S41398-019-0608-1  0.293
2014 Yang H, Wang G, Sun H, Shu R, Liu T, Wang CE, Liu Z, Zhao Y, Zhao B, Ouyang Z, Yang D, Huang J, Zhou Y, Li S, Jiang X, ... ... Li XJ, et al. Species-dependent neuropathology in transgenic SOD1 pigs. Cell Research. 24: 464-81. PMID 24577199 DOI: 10.1038/Cr.2014.25  0.293
2022 Sun Y, Tong H, Yang T, Liu L, Li XJ, Li S. Insights into White Matter Defect in Huntington's Disease. Cells. 11. PMID 36359783 DOI: 10.3390/cells11213381  0.292
2013 Kocerha J, Liu Y, Willoughby D, Chidamparam K, Benito J, Nelson K, Xu Y, Chi T, Engelhardt H, Moran S, Yang SH, Li SH, Li XJ, Larkin K, Neumann A, et al. Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington's disease monkeys. Bmc Neuroscience. 14: 88. PMID 23957861 DOI: 10.1186/1471-2202-14-88  0.292
2023 Jia Q, Bai D, Zheng X, Zhu L, Ou K, Wang X, Tong H, Zhang Y, Wang J, Zeng J, Yan S, Li S, Li XJ, Yin P. Comparing HD knockin pigs and mice reveals the pathological role of IL-17. Cell Reports. 42: 113443. PMID 37979175 DOI: 10.1016/j.celrep.2023.113443  0.289
2022 Han R, Liu Y, Li S, Li XJ, Yang W. PINK1-PRKN mediated mitophagy: differences between and models. Autophagy. 1-10. PMID 36282767 DOI: 10.1080/15548627.2022.2139080  0.284
2008 Colin E, Zala D, Liot G, Rangone H, Borrell-Pagès M, Li XJ, Saudou F, Humbert S. Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. The Embo Journal. 27: 2124-34. PMID 18615096 DOI: 10.1038/Emboj.2008.133  0.278
2021 Yang W, Chen X, Li S, Li XJ. Genetically modified large animal models for investigating neurodegenerative diseases. Cell & Bioscience. 11: 218. PMID 34933675 DOI: 10.1186/s13578-021-00729-8  0.276
2017 Tu Z, Yang W, Yan S, Yin A, Gao J, Liu X, Zheng Y, Zheng J, Li Z, Yang S, Li S, Guo X, Li XJ. Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos. Scientific Reports. 7: 42081. PMID 28155910 DOI: 10.1038/Srep42081  0.272
2015 Guo X, Li XJ. Targeted genome editing in primate embryos. Cell Research. 25: 767-8. PMID 26032266 DOI: 10.1038/Cr.2015.64  0.268
2024 Chen XS, Han R, Liu YT, Huang W, Wang Q, Xiong X, Zhang Y, Zhao JG, Li SH, Li XJ, Yang WL. Comparative analysis of primate and pig cells reveals primate-specific PINK1 expression and phosphorylation. Zoological Research. 45: 242-252. PMID 38287905 DOI: 10.24272/j.issn.2095-8137.2023.241  0.263
2020 Pan Y, Liu Q, Zhang J, Yang Y, Tian Y, Zeng J, Yin P, Mei L, Xiong WC, Li XJ, Li S, Tang B. Corrigendum to "PRRT2 frameshift mutation reduces its mRNA stability resulting loss of function in paroxysmal kinesigenic dyskinesia". Biochemical and Biophysical Research Communications. PMID 32169279 DOI: 10.1016/J.Bbrc.2020.02.159  0.257
2012 Wang H, Huang Z, Huang L, Niu S, Rao X, Xu J, Kong H, Yang J, Yang C, Wu D, Li S, Li XJ, Liu T, Sheng G. Hypothalamic Ahi1 mediates feeding behavior through interaction with 5-HT2C receptor. The Journal of Biological Chemistry. 287: 2237-46. PMID 22123816 DOI: 10.1074/Jbc.M111.277871  0.256
2023 Lin Y, Li C, Wang W, Li J, Huang C, Zheng X, Liu Z, Song X, Chen Y, Gao J, Wu J, Wu J, Tu Z, Lai L, Li XJ, et al. Intravenous AAV9 administration results in safe and widespread distribution of transgene in the brain of mini-pig. Frontiers in Cell and Developmental Biology. 10: 1115348. PMID 36762127 DOI: 10.3389/fcell.2022.1115348  0.252
2023 Tu Z, Yan S, Han B, Li C, Liang W, Lin Y, Ding Y, Wei H, Wang L, Xu H, Ye J, Li B, Li S, Li XJ. Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys. Signal Transduction and Targeted Therapy. 8: 358. PMID 37735155 DOI: 10.1038/s41392-023-01601-6  0.25
2014 Zheng Y, Li X. TALEN-mediated gene mutations in monkeys Neuroscience Bulletin. 30: 379-380. DOI: 10.1007/S12264-013-1436-6  0.247
2013 Ning J, Zhang H, Li X, Zhong P, Tang Y, Liu Z. Characteristics of stable nitrogen isotopes in particulate organic matter and periphyton of a subtropical Chinese watercourse, the Dashahe River Knowledge and Management of Aquatic Ecosystems. 9. DOI: 10.1051/Kmae/2013065  0.247
2017 Li XJ, Tu Z, Yang W, Li S. CRISPR: Established Editor of Human Embryos? Cell Stem Cell. 21: 295-296. PMID 28886363 DOI: 10.1016/J.Stem.2017.08.007  0.245
2022 Liu X, Li XJ, Lin L. Dynamic 5-Hydroxymethylcytosine Change: Implication for Aging of Non-Human Primate Brain. Epigenomes. 6. PMID 36547250 DOI: 10.3390/epigenomes6040041  0.235
2022 Yin P, Li S, Li XJ, Yang W. New pathogenic insights from large animal models of neurodegenerative diseases. Protein & Cell. PMID 35334073 DOI: 10.1007/s13238-022-00912-8  0.234
2023 Li B, Zhao H, Tu Z, Yang W, Han R, Wang L, Luo X, Pan M, Chen X, Zhang J, Xu H, Guo X, Yan S, Yin P, Zhao Z, ... ... Li XJ, et al. CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate. Cell Discovery. 9: 27. PMID 36878905 DOI: 10.1038/s41421-023-00525-3  0.234
2024 Pan MT, Zhang H, Li XJ, Guo XY. Genetically modified non-human primate models for research on neurodegenerative diseases. Zoological Research. 45: 263-274. PMID 38287907 DOI: 10.24272/j.issn.2095-8137.2023.197  0.233
2000 Tan Q, Li X, Sadhale PP, Miyao T, Woychik NA. Multiple mechanisms of suppression circumvent transcription defects in an RNA polymerase mutant. Molecular and Cellular Biology. 20: 8124-33. PMID 11027282 DOI: 10.1128/Mcb.20.21.8124-8133.2000  0.232
2020 Yang H, Yang S, Jing L, Huang L, Chen L, Zhao X, Yang W, Pan Y, Yin P, Qin ZS, Tang B, Li S, Li XJ. Author Correction: Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form. Nature Communications. 11: 5989. PMID 33214567 DOI: 10.1038/s41467-020-19873-9  0.228
2023 Xie J, Xie L, Wei H, Li XJ, Lin L. Dynamic Regulation of DNA Methylation and Brain Functions. Biology. 12. PMID 36829430 DOI: 10.3390/biology12020152  0.227
1996 Shou W, Li X, Wu C, Cao T, Kuang J, Che S, Etkin LD. Finely tuned regulation of cytoplasmic retention of Xenopus nuclear factor 7 by phosphorylation of individual threonine residues. Molecular and Cellular Biology. 16: 990-7. PMID 8622702 DOI: 10.1128/MCB.16.3.990  0.225
2007 Palfi S, Brouillet E, Jarraya B, Bloch J, Jan C, Shin M, Condé F, Li XJ, Aebischer P, Hantraye P, Déglon N. Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1444-51. PMID 17505477 DOI: 10.1038/Sj.Mt.6300185  0.201
2022 Chen X, Wang Q, Li S, Li XJ, Yang W. Mitochondrial-Dependent and Independent Functions of PINK1. Frontiers in Cell and Developmental Biology. 10: 954536. PMID 35874823 DOI: 10.3389/fcell.2022.954536  0.2
2003 Li SH, Li XJ. In vitro expression systems for the Huntington protein. Methods in Molecular Biology (Clifton, N.J.). 217: 277-84. PMID 12491940 DOI: 10.1385/1-59259-330-5:277  0.198
2010 Zhang DF, Li XG, Su LJ, Meng QL. Expression of activin A and follistatin in glioblastoma and their effects on U87 in vitro. The Journal of International Medical Research. 38: 1343-53. PMID 20926007 DOI: 10.1177/147323001003800416  0.198
2015 Niu Y, Guo X, Chen Y, Wang CE, Gao J, Yang W, Kang Y, Si W, Wang H, Yang SH, Li S, Ji W, Li XJ. Early Parkinson's disease symptoms in α-synuclein transgenic monkeys. Human Molecular Genetics. 24: 2308-17. PMID 25552648 DOI: 10.1093/hmg/ddu748  0.194
2023 Wang Z, Wang Q, Li S, Li XJ, Yang W, He D. Microglial autophagy in Alzheimer's disease and Parkinson's disease. Frontiers in Aging Neuroscience. 14: 1065183. PMID 36704504 DOI: 10.3389/fnagi.2022.1065183  0.189
2022 Xu Y, Zhong L, Wei H, Li Y, Xie J, Xie L, Chen X, Guo X, Yin P, Li S, Zeng J, Li XJ, Lin L. Brain Region- and Age-Dependent 5-Hydroxymethylcytosine Activity in the Non-Human Primate. Frontiers in Aging Neuroscience. 14: 934224. PMID 35912074 DOI: 10.3389/fnagi.2022.934224  0.189
2015 Chen Y, Zheng Y, Kang Y, Yang W, Niu Y, Guo X, Tu Z, Si C, Wang H, Xing R, Pu X, Yang SH, Li S, Ji W, Li XJ. Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9. Human Molecular Genetics. 24: 3764-74. PMID 25859012 DOI: 10.1093/hmg/ddv120  0.185
2013 Fang Z, Li X, Wang GGX. A gas mixture enhanced coalbed methane recovery technology applied to underground coal mines Journal of Mining Science. 49: 106-117. DOI: 10.1134/S1062739149010139  0.184
2022 Lin Y, Li J, Li C, Tu Z, Li S, Li XJ, Yan S. Application of CRISPR/Cas9 System in Establishing Large Animal Models. Frontiers in Cell and Developmental Biology. 10: 919155. PMID 35656550 DOI: 10.3389/fcell.2022.919155  0.183
2012 Chen Z, Liu C, Li X, Tang J, Tan C, Yu H, Huang H. 2.020 Semi-Automated Synthesis, Biodistribution And Micropet Imaging Of 18F-Fp-Dtbz As A Vesicular Monoamine Transporter Ligand Parkinsonism & Related Disorders. 18. DOI: 10.1016/S1353-8020(11)70453-9  0.18
2023 Zhu L, Li S, Li XJ, Yin P. Pathological insights from amyotrophic lateral sclerosis animal models: comparisons, limitations, and challenges. Translational Neurodegeneration. 12: 46. PMID 37730668 DOI: 10.1186/s40035-023-00377-7  0.179
2022 Qin Y, Li S, Li XJ, Yang S. CRISPR-Based Genome-Editing Tools for Huntington's Disease Research and Therapy. Neuroscience Bulletin. PMID 35608753 DOI: 10.1007/s12264-022-00880-3  0.172
1999 Wang X, Li X, Yaish-Ohad S, Sarau HM, Barone FC, Feuerstein GZ. Molecular cloning and expression of the rat monocyte chemotactic protein-3 gene: a possible role in stroke. Brain Research. Molecular Brain Research. 71: 304-12. PMID 10521584 DOI: 10.1016/S0169-328X(99)00203-X  0.168
2021 Wang B, Xin N, Qian X, Zhai L, Miao Z, Yang Y, Li S, Sun M, Xu X, Li XJ. Ahi1 regulates the nuclear translocation of glucocorticoid receptor to modulate stress response. Translational Psychiatry. 11: 188. PMID 33782379 DOI: 10.1038/s41398-021-01305-x  0.152
2023 Xie L, Zhang X, Xie J, Xu Y, Li XJ, Lin L. Emerging Roles for DNA 6mA and RNA m6A Methylation in Mammalian Genome. International Journal of Molecular Sciences. 24. PMID 37762200 DOI: 10.3390/ijms241813897  0.149
2001 Anusaksathien O, Laplace C, Li X, Ren Y, Peng L, Goldring SR, Galson DL. Tissue-specific and ubiquitous promoters direct the expression of alternatively spliced transcripts from the calcitonin receptor gene. The Journal of Biological Chemistry. 276: 22663-74. PMID 11309373 DOI: 10.1074/jbc.M007104200  0.146
2001 Henry RA, Tews B, Li X, Scott MJ. Recruitment of the Male-specific Lethal (MSL) Dosage Compensation Complex to an Autosomally Integrated roX Chromatin Entry Site Correlates with an Increased Expression of an Adjacent Reporter Gene in Male Drosophila Journal of Biological Chemistry. 276: 31953-31958. PMID 11402038 DOI: 10.1074/jbc.M103008200  0.144
1994 Tachibana M, Perez-Jurado LA, Nakayama A, Hodgkinson CA, Li X, Schneider M, Miki T, Fex J, Francke U, Arnheiter H. Cloning of MITF, the human homolog of the mouse microphthalmia gene and assignment to chromosome 3p14.1-p12.3 Human Molecular Genetics. 3: 553-557. PMID 8069297 DOI: 10.1093/Hmg/3.4.553  0.139
2002 Li XL, Aou S, Oomura Y, Hori N, Fukunaga K, Hori T. Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents. Neuroscience. 113: 607-15. PMID 12150780 DOI: 10.1016/S0306-4522(02)00162-8  0.127
2016 Ren YX, Yang J, Sun RM, Zhang LJ, Zhao LF, Li BZ, Li L, Long HT, Sun QM, Huang YC, Li XJ. Viral IL-10 down-regulates the "MHC-I antigen processing operon" through the NF-κB signaling pathway in nasopharyngeal carcinoma cells. Cytotechnology. PMID 27650182 DOI: 10.1007/s10616-016-9987-9  0.122
2024 Li XJ, Lai L. A booming field of large animal model research. Zoological Research. 45: 311-313. PMID 38485501 DOI: 10.24272/j.issn.2095-8137.2024.018  0.12
2024 Han B, Liang W, Li XJ, Li S, Yan S, Tu Z. Large animal models for Huntington's disease research. Zoological Research. 45: 275-283. PMID 38485497 DOI: 10.24272/j.issn.2095-8137.2023.199  0.12
2008 Yan QL, Li XJ, Wang H, Nie LH, Zhang ZY, Gao HX. Thermal decomposition and kinetics studies on 1,4-dinitropiperazine (DNP). Journal of Hazardous Materials. 151: 515-21. PMID 17629621 DOI: 10.1016/j.jhazmat.2007.06.019  0.118
1998 Vavvas D, Li X, Avruch J, Zhang XF. Identification of Nore1 as a potential Ras effector. The Journal of Biological Chemistry. 273: 5439-42. PMID 9488663 DOI: 10.1074/jbc.273.10.5439  0.113
2000 Wang X, Li X, Erhardt JA, Barone FC, Feuerstein GZ. Detection of tumor necrosis factor-alpha mRNA induction in ischemic brain tolerance by means of real-time polymerase chain reaction. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 15-20. PMID 10616788 DOI: 10.1097/00004647-200001000-00004  0.104
1996 Park WJ, Meyers GA, Li X, Theda C, Day D, Orlow SJ, Jones MC, Jabs EW. Novel FGFR2 mutations in Crouzon and Jackson-Weiss syndromes show allelic heterogeneity and phenotypic variability. Human Molecular Genetics. 4: 1229-33. PMID 8528214 DOI: 10.1093/Hmg/4.7.1229  0.102
2014 Ren YX, Yang J, Zhang LJ, Sun RM, Zhao LF, Zhang M, Chen Y, Ma J, Qiao K, Sun QM, Long HT, Huang YC, Li XJ. Downregulation of expression of transporters associated with antigen processing 1 and 2 and human leukocyte antigen I and its effect on immunity in nasopharyngeal carcinoma patients. Molecular and Clinical Oncology. 2: 51-58. PMID 24649307 DOI: 10.3892/mco.2013.194  0.101
2008 Mei L, Cho K, Lee CJ, Li XJ, Zhuo M, Kaang BK. Welcome to molecular brain. Molecular Brain. 1: 1. PMID 18803854 DOI: 10.1186/1756-6606-1-1  0.098
2016 Lam SM, Chua GH, Li XJ, Su B, Shui G. Biological relevance of fatty acyl heterogeneity to the neural membrane dynamics of Rhesus macaques during normative aging. Oncotarget. PMID 27517158 DOI: 10.18632/oncotarget.11190  0.095
2009 Shi Z, Liang N, Xu W, Li K, Sheng G, Liu J, Xu A, Li XJ, Wu D. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the SH3 domain of human AHI1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 361-3. PMID 19342780 DOI: 10.1107/S174430910900774X  0.092
2000 Wang X, Li X, Currie RW, Willette RN, Barone FC, Feuerstein GZ. Application of real-time polymerase chain reaction to quantitate induced expression of interleukin-1beta mRNA in ischemic brain tolerance. Journal of Neuroscience Research. 59: 238-46. PMID 10650882 DOI: 10.1002/(SICI)1097-4547(20000115)59:2<238::AID-JNR10>3.0.CO;2-G  0.091
2024 Xie J, Wang Y, Ye C, Li XJ, Lin L. Distinctive Patterns of 5-Methylcytosine and 5-Hydroxymethylcytosine in Schizophrenia. International Journal of Molecular Sciences. 25. PMID 38203806 DOI: 10.3390/ijms25010636  0.086
2015 Kong F, Shi X, Li H, Li P, Yu J, Li X, Chen J, Sun Y, Jia Y. Increased expression of iASPP correlates with poor prognosis in FIGO IA2-IIA cervical adenocarcinoma following a curative resection. American Journal of Cancer Research. 5: 1217-24. PMID 26046000  0.08
2010 Sui J, Mo Q, Li XJ, Ma J, Ren YX, Gao W, Wang H, Yang J. [Transporter associated with antigen processing 1 637A/G gene polymorphisms and susceptibility to nasopharyngeal carcinoma in Han population in Yunnan Province, China]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 45: 238-43. PMID 20450707  0.064
2005 Wang H, Li XJ, Zhang SW, Xi Y. [Clinical study of extranodal NK-T cell lymphoma-nasal type]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 40: 850-4. PMID 16408753  0.063
1991 Nordén G, Björck S, Persson H, Svalander C, Li XG, Edebo L. Cure of zygomycosis caused by a lipase-producing Rhizopus rhizopodiformis strain in a renal transplant patient. Scandinavian Journal of Infectious Diseases. 23: 377-82. PMID 1882202 DOI: 10.3109/00365549109024326  0.063
2017 Wu D, Xu J, Peng JM, Ma LK, Chen S, Li XG, Zhang TP, Qian JM. [The 454th case: a 29-week pregnant woman with abdominal pain, hyperlipemia and multiorgan dysfunction]. Zhonghua Nei Ke Za Zhi. 56: 157-160. PMID 28162192 DOI: 10.3760/cma.j.issn.0578-1426.2017.02.018  0.061
2018 Li PP, Li B, Wang YT, Liu SH, Zhang YN, Zhang R, Bai P, Li XG, Wu LY. [Prognostic analysis of stage Ⅰb2 andⅡa2 cervical squamous cancer without high risk factors treated with neo-adjuvant chemotherapy and radical hysterectomy]. Zhonghua Fu Chan Ke Za Zhi. 53: 248-256. PMID 29747270 DOI: 10.3760/cma.j.issn.0529-567x.2018.04.008  0.056
2011 Wang XY, Xu SJ, Li XG. Post-operative implantation metastasis of craniopharyngioma: a case report. The Journal of International Medical Research. 38: 1876-82. PMID 21309505 DOI: 10.1177/147323001003800536  0.055
2015 Tang HL, Shi WL, Li XG, Zhang T, Zhai SD, Xie HG. Limited clinical utility of genotype-guided warfarin initiation dosing algorithms versus standard therapy: a meta-analysis and trial sequential analysis of 11 randomized controlled trials. The Pharmacogenomics Journal. PMID 25869011 DOI: 10.1038/tpj.2015.16  0.051
2007 Li GP, Li XJ, Sui J, Chen SC, Liu ZL. [Applied anatomy study on the reversed submental island flap]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 42: 268-72. PMID 17628976  0.044
2007 Zhang ZQ, Chen YQ, Chen YA, Wu X, Wang YB, Li XG. Chiari I malformation associated with syringomyelia: a retrospective study of 316 surgically treated patients. Spinal Cord. 46: 358-63. PMID 18026173 DOI: 10.1038/sj.sc.3102141  0.043
2022 Zhang X, Wang W, Guo RT, Pan WG, Li XJ. Study on the Effect of Pyrolysis Conditions on the Combustion Behavior and Char Structure Evolution. Acs Omega. 7: 23634-23642. PMID 35847288 DOI: 10.1021/acsomega.2c02231  0.041
2008 Sui J, Cao XJ, Li XJ. [Correlation between the vascular endothelial growth factor C expression and lymph node metastasis in human nasopharyngeal carcinoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 43: 524-8. PMID 18826121  0.04
2013 Sun RM, Wang JD, Li Q, Yang J, Li GP, Zhao LF, Liu ZL, Li XJ. [Anatomical study of improved lateral arm free flap]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 48: 37-41. PMID 23656814  0.04
2017 Wu HX, Paerhati R, Feng GJ, Yang XP, Zhao P, Liu QL, Li G, Li XG, Wang DH. [Clinical application of hybrid surgery for the treatment of cerebral arteriovenous malformations]. Zhonghua Yi Xue Za Zhi. 97: 817-821. PMID 28355735 DOI: 10.3760/cma.j.issn.0376-2491.2017.11.005  0.037
2011 Ji LL, Yang ZH, Xu ZY, Li XJ, Tang ZG, Deng JH. [Achieve single-stage autotrophic biological nitrogen removal process by controlling the concentration of free ammonia]. Huan Jing Ke Xue= Huanjing Kexue / [Bian Ji, Zhongguo Ke Xue Yuan Huan Jing Ke Xue Wei Yuan Hui "Huan Jing Ke Xue" Bian Ji Wei Yuan Hui.]. 32: 199-205. PMID 21404687  0.037
2009 Yan Q, Li X, Wang Y, Zhang W, Zhao F. Combustion mechanism of double-base propellant containing nitrogen heterocyclic nitroamines (I): The effect of heat and mass transfer to the burning characteristics Combustion and Flame. 156: 633-641. DOI: 10.1016/j.combustflame.2008.12.004  0.036
2022 Yang W, Li S, Li XJ. AHI1: linking depression and impaired antiviral immune response. Cell Research. PMID 35859186 DOI: 10.1038/s41422-022-00702-1  0.035
2007 Sun CZ, Chen FJ, Li XJ, Zeng ZY, Sui J, Deng LF, Chen YF. [Prognostic analysis of moderate tongue squamous cell carcinoma cases and the value of induction chemotherapy]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 42: 273-6. PMID 17628977  0.034
2011 Wu X, Yan Q, Guo X, Qi X, Li X, Wang K. Combustion efficiency and pyrochemical properties of micron-sized metal particles as the components of modified double-base propellant Acta Astronautica. 68: 1098-1112. DOI: 10.1016/j.actaastro.2010.09.028  0.031
2014 Wang N, Zhang S, Zhang AF, Yang ZY, Li XG. Sodium hyaluronate-CNTF gelatinous particles promote axonal growth, neurogenesis and functional recovery after spinal cord injury. Spinal Cord. 52: 517-23. PMID 24796451 DOI: 10.1038/sc.2014.54  0.031
2018 Chen TN, Yin XT, Li XG, Zhao J, Wang L, Mu N, Ma K, Huo K, Liu D, Gao BY, Feng H, Li F. [Application of 3D virtual reality technology with multi-modality fusion in resection of glioma located in central sulcus region]. Zhonghua Yi Xue Za Zhi. 98: 1302-1305. PMID 29764028 DOI: 10.3760/cma.j.issn.0376-2491.2018.17.004  0.03
2016 Yuan GW, Yao HW, Li XG, Li HJ, Wu LY. [Analysis of 13 cases of rhabdomyosarcoma in the female genital tract]. Zhonghua Fu Chan Ke Za Zhi. 51: 264-9. PMID 27116984 DOI: 10.3760/cma.j.issn.0529-567X.2016.04.005  0.03
2008 Jia YJ, Li XJ, Zhang Y. [Clinical observation of airening suppository in treatment of 30 patients with carcinoma fever]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban. 28: 318-21. PMID 18543484  0.028
2009 Sui J, Gao W, Li XJ, Ma J, Ren YX, Song X, Xiao CJ, Tang WR. [Cyclin D1 gene G870A polymorphism and susceptibility to nasopharyngeal carcinoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 44: 227-31. PMID 19558863  0.028
2017 Mou RY, Li XJ. [Laboratory techniques for the diagnosis of prostate cancer: An update]. Zhonghua Nan Ke Xue = National Journal of Andrology. 23: 372-375. PMID 29714425  0.027
1996 Lin G, Ho YP, Li P, Li XG. Puqiedinone, a novel 5 alpha-cevanine alkaloid from the bulbs of Fritillaria puqiensis, an antitussive traditional Chinese medicine. Journal of Natural Products. 58: 1662-7. PMID 8594143 DOI: 10.1021/np50125a003  0.024
2016 Wu XB, Zhang GT, Zhang F, Gan WD, Liu GX, Li XG, Zhang SW, Guo HQ. [Safety and efficacy of partial nephrectomy for solitary kidney tumor]. Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. 54: 746-750. PMID 27686637 DOI: 10.3760/cma.j.issn.0529-5815.2016.10.005  0.023
2017 Zhao P, Wu HX, Paerhati R, Liu QL, Wang YY, Li G, Li XG, Wang DH. [Management of 42 complex intracranial aneurysms in hybrid operating room]. Zhonghua Yi Xue Za Zhi. 97: 810-813. PMID 28355733 DOI: 10.3760/cma.j.issn.0376-2491.2017.11.003  0.022
2000 Savitz SI, Erhardt JA, Anthony JV, Gupta G, Li X, Barone FC, Rosenbaum DM. The novel beta-blocker, carvedilol, provides neuroprotection in transient focal stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 1197-204. PMID 10950380 DOI: 10.1097/00004647-200008000-00005  0.019
2020 Li WJ, Mo RY, Li XJ. [Progress in the treatment of oligometastatic prostate cancer]. Zhonghua Nan Ke Xue = National Journal of Andrology. 26: 832-837. PMID 33377709  0.018
2009 Yan Q, Li X, Chen Z, Ren X, Nie L. Thermal Behavior and Thermolysis Kinetics of the Explosive Trans-1,4,5,8-Tetranitro-1,4,5,8-Tetraazadecalin (TNAD) Propellants, Explosives, Pyrotechnics. 34: 357-362. DOI: 10.1002/prep.200800006  0.018
2013 Jia YJ, Li XJ, Li C, Zhao C. [Clinical efficacy analysis of treating advanced prostate cancer by yiqi jiedu quyu recipe combined endocrine therapy]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban. 33: 448-51. PMID 23841259  0.015
2003 Zhao Z, Li S, Wen H, Li X. Dimensional crossover of vortex dynamics induced by Gd substitution on Bi2212 single crystals Physica C: Superconductivity. 391: 169-177. DOI: 10.1016/S0921-4534(03)00890-6  0.013
2011 Li XJ, Jia YJ, Chen L. [Clinical observation of thermotherapy combined with thoracic injection of lentinan in treatment of cancerous hydrothorax of patients with lung cancer]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban. 31: 1062-5. PMID 21910335  0.013
2014 Zhang YC, Jia YJ, Yang PY, Zhang X, Li XJ, Zhang Y, Zhu JL, Sun YY, Chen J, Duan HG, Guo H, Li C. [Mechanism study on leptin resistance in lung cancer cachexia rats treated by Xiaoyan Decoction]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine / Zhongguo Zhong Xi Yi Jie He Xue Hui, Zhongguo Zhong Yi Yan Jiu Yuan Zhu Ban. 34: 1512-6. PMID 25632755  0.012
2005 Zhang X, Wu LY, Li XJ, Li HJ, Zhang R, Liu LY. [Clinical analysis of benign pelvic mass with high serum levels of CA(125)]. Zhonghua Fu Chan Ke Za Zhi. 40: 178-82. PMID 15840313  0.011
2021 Ren YX, Yang J, Sun WZ, Chen Y, Wu XF, Huang N, Li XJ. Application of lateral supraclavicular incision in unilateral thyroid papillary carcinoma surgery. Brazilian Journal of Otorhinolaryngology. PMID 34119426 DOI: 10.1016/j.bjorl.2021.03.010  0.01
2015 Xu WT, Jia YJ, Li XJ, Chen J. [MicroRNAs and prostate cancer]. Zhonghua Nan Ke Xue = National Journal of Andrology. 21: 458-62. PMID 26117946  0.01
2015 Wu P, Wang XY, Li XG, Shen XJ, Pang XY, Luo CK, Xu ZQ, Zeng H, Zhang PH, Peng W. One-stage posterior procedure in treating active thoracic spinal tuberculosis: a retrospective study. European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society. 41: 189-97. PMID 26038264 DOI: 10.1007/s00068-014-0421-8  0.01
2006 Li XJ, Zhang SW, Sun RM, Ma J, Sui J. [Endoscope-assisted thyroidectomy with minimal incision in neck]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 41: 521-3. PMID 17007379  0.01
2005 Wang H, Li XJ, Zhang SW, Xi Y. [Diagnosis and reoperation for thyroid carcinoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery. 40: 601-5. PMID 16270879  0.01
2003 Li XJ, Wu LY, Li XG, Sun YC. [Analysis of 20 cases of pelvic tuberculosis initially suspected of ovarian carcinoma]. Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases. 26: 462-4. PMID 14505521  0.01
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