Florian Freudenberg, PhD - Publications

Affiliations: 
Psychiatry, Psychosomatics and Psychotherapy University Hospital of Frankfurt 
Area:
Synaptic plasticity, AMPA receptors, Depression

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Freudenberg F, Reif-Leonhard C, Reif A. Advancing past ketamine: emerging glutamatergic compounds for the treatment of depression. European Archives of Psychiatry and Clinical Neuroscience. PMID 39207462 DOI: 10.1007/s00406-024-01875-z  0.521
2024 Yotova AY, Li LL, O'Leary A, Tegeder I, Reif A, Courtney MJ, Slattery DA, Freudenberg F. Synaptic proteome perturbations after maternal immune activation: Identification of embryonic and adult hippocampal changes. Brain, Behavior, and Immunity. 121: 351-364. PMID 39089536 DOI: 10.1016/j.bbi.2024.07.040  0.529
2023 Yotova A, Li LL, O'Leary A, Tegeder I, Reif A, Courtney M, Slattery D, Freudenberg F. Embryonic and adult synaptic proteome perturbations after maternal immune activation: Identification of persistent changes relevant for early intervention. Research Square. PMID 37461513 DOI: 10.21203/rs.3.rs-3100753/v1  0.718
2022 Candemir E, Fattakhov N, Leary AO, Slattery DA, Courtney MJ, Reif A, Freudenberg F. Disrupting the nNOS/NOS1AP interaction in the medial prefrontal cortex impairs social recognition and spatial working memory in mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 67: 66-79. PMID 36513018 DOI: 10.1016/j.euroneuro.2022.11.006  0.598
2022 Freudenberg F, Althen H, Falk K, Bittner RA, Reif A, Plichta MM. Test-Retest reliability of prepulse inhibition (PPI) and PPI correlation with working memory. Acta Neuropsychiatrica. 1-29. PMID 35959694 DOI: 10.1017/neu.2022.19  0.472
2022 O'Leary A, Fernàndez-Castillo N, Gan G, Yang Y, Yotova AY, Kranz TM, Grünewald L, Freudenberg F, Antón-Galindo E, Cabana-Domínguez J, Harneit A, Schweiger JI, Schwarz K, Ma R, Chen J, et al. Behavioural and functional evidence revealing the role of RBFOX1 variation in multiple psychiatric disorders and traits. Molecular Psychiatry. PMID 35948661 DOI: 10.1038/s41380-022-01722-4  0.725
2022 Esen-Sehir D, Kopf J, Hägele S, Plichta MM, Reif A, Freudenberg F. Influence of NOS1AP Risk Variants on the Corrected QT (QTc) Interval in the Pharmacotherapy of Schizophrenia. Pharmacopsychiatry. PMID 35732169 DOI: 10.1055/a-1811-7241  0.543
2022 McNeill RV, Kehrwald C, Brum M, Knopf K, Brunkhorst-Kanaan N, Etyemez S, Koreny C, Bittner R, Freudenberg F, Herterich S, Reif A, Kittel-Schneider S. Uncovering associations between mental illness diagnosis, nitric oxide synthase gene variation, and peripheral nitric oxide concentration. Brain, Behavior, and Immunity. PMID 35041938 DOI: 10.1016/j.bbi.2022.01.006  0.54
2021 Freudenberg F, Candemir E, Chen X, Li LL, Esen-Sehir D, Schenk N, Kinoshita M, Grünewald L, Frerichs V, Fattakhov N, Manchen J, Bikas S, Kumar A, OLeary A, Slattery DA, et al. Hippocampal overexpression of NOS1AP promotes endophenotypes related to mental disorders. Ebiomedicine. 71: 103565. PMID 34455393 DOI: 10.1016/j.ebiom.2021.103565  0.581
2020 Arsović A, Halbach MV, Canet-Pons J, Esen-Sehir D, Döring C, Freudenberg F, Czechowska N, Seidel K, Baader SL, Gispert S, Sen NE, Auburger G. Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength. International Journal of Molecular Sciences. 21. PMID 32932600 DOI: 10.3390/Ijms21186673  0.336
2020 Raspor E, Hahn PK, Lancaster T, Linden DEJ, Freudenberg F, Reif A, Bittner RA. S177. IMPACT OF NOS1AP AND ITS INTERACTION PARTNERS AT THE GLUTAMATERGIC SYNAPSE ON WORKING MEMORY NETWORKS - AN FMRI IMAGING GENETICS STUDY Schizophrenia Bulletin. 46: S105-S105. DOI: 10.1093/Schbul/Sbaa031.243  0.629
2019 Esen-Sehir D, Courtney MJ, Bittner RA, Reif A, Freudenberg F. Establishing an effective dose for chronic intracerebroventricular administration of clozapine in mice. Acta Neuropsychiatrica. 1-23. PMID 31364522 DOI: 10.1017/Neu.2019.31  0.566
2019 Mortimer N, Ganster T, O'Leary A, Popp S, Freudenberg F, Reif A, Artigas MS, Ribasés M, Ramos-Quiroga JA, Lesch KP, Rivero O. Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3: Evidence for dopamine transporter dysregulation. Neuropharmacology. PMID 30849401 DOI: 10.1016/J.Neuropharm.2019.02.039  0.622
2019 Grünewald L, Chiocchetti AG, Weber H, Scholz CJ, Schartner C, Freudenberg F, Reif A. Knockdown of the ADHD Candidate Gene Diras2 in Murine Hippocampal Primary Cells. Journal of Attention Disorders. 1087054718822129. PMID 30623719 DOI: 10.1177/1087054718822129  0.547
2019 Esen D, Silva BSd, Slattery D, Reif A, Freudenberg F. Establishing an effective dose for chronic intracerebroventricular administration of clozapine in mice European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.11.839  0.533
2019 Kinoshita M, Candemir E, Kittel-Schneider S, Reif A, Freudenberg F. A gene expression study of the glutamate-nitric oxide pathway in schizophrenia European Neuropsychopharmacology. 29: S274-S275. DOI: 10.1016/J.Euroneuro.2018.11.434  0.58
2019 O'Leary A, Candemir E, Freudenberg F, Reif A, Slattery D. Is the alternative splicing factor Rbfox1 associated with aggressive behaviour in mouse models? European Neuropsychopharmacology. 29: S259. DOI: 10.1016/J.Euroneuro.2018.11.409  0.536
2019 Reif A, Freudenberg F, Candemir E, Fernàndez-Castillo N, Cormand B, Chiocchetti A, Slattery DA, O'Leary A. 14. Conditional Knockout of Rbfox1, a Cross-Disorder Psychiatric Risk Gene, Causes an Autism-Like Phenotype in Mice Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.028  0.599
2018 Grünewald L, Becker N, Camphausen A, O'Leary A, Lesch KP, Freudenberg F, Reif A. Expression of the ADHD candidate gene Diras2 in the brain. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 29488099 DOI: 10.1007/S00702-018-1867-3  0.584
2018 Candemir E, Fattakhov N, Li L, Chen X, Esen D, Frerichs V, Arshad S, Grünewald L, O'Leary A, Slattery DA, Engelhardt Jv, Courtney MJ, Reif A, Freudenberg F. F193. Overexpression of NOS1AP in Dorsal Hippocampus and Medial Prefrontal Cortex Induces Schizophrenia-Related Phenotypic Changes Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.807  0.563
2018 Kittel-Schneider S, Palladino VS, Subrata NOC, Auer J, Grein A, Freudenberg F, Reif A. T95. Functional Characterization of a DGKH Genetic Risk Variant for Bipolar Disorder in a Cell Model Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.431  0.566
2017 Gutiérrez HC, O'Leary A, Freudenberg F, Fedele G, Wilkinson R, Markham E, van Eeden F, Reif A, Norton WHJ. Nitric oxide interacts with monoamine oxidase to modulate aggression and anxiety-like behaviour. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 28951000 DOI: 10.1016/J.Euroneuro.2017.09.004  0.587
2017 Schartner C, Scholz CJ, Weber H, Post A, Freudenberg F, Grünewald L, Reif A. The regulation of tetraspanin 8 gene expression-A potential new mechanism in the pathogenesis of bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 28777493 DOI: 10.1002/Ajmg.B.32571  0.609
2017 Candemir E, Fattakhov N, Frerichs V, Arshad S, O’Leary A, Grünewald L, Schneider M, Slattery D, Reif A, Freudenberg F. Disrupting protein-protein interactions of neuronal nitric oxide synthase: implications in schizophrenia-related behaviours European Neuropsychopharmacology. 27: S887-S888. DOI: 10.1016/S0924-977X(17)31585-7  0.592
2017 O’Leary A, Freudenberg F, Candemir E, Grünewald L, Reif A. Reduced aggression, social impairments, and cognitive inflexibility in neuronal nitric oxide (Nos1) knockdown mice European Neuropsychopharmacology. 27: S677-S678. DOI: 10.1016/S0924-977X(17)31261-0  0.566
2017 Candemir E, Fattakhov N, O׳Leary A, Grünewald L, Schneider M, Reif A, Freudenberg F. 502. Disrupting Protein-Protein Interactions of Neuronal Nitric Oxide in the Medial Prefrontal Cortex and Dorsal Hippocampus: Implications in Schizophrenia-Related Behaviors Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.1110  0.597
2016 Freudenberg F, Resnik E, Kolleker A, Celikel T, Sprengel R, Seeburg PH. Hippocampal GluA1 expression in Gria1(-/-) mice only partially restores spatial memory performance deficits. Neurobiology of Learning and Memory. PMID 27417577 DOI: 10.1016/J.Nlm.2016.07.005  0.74
2016 Weißflog L, Becker N, Bossert N, Freudenberg F, Kittel-Schneider S, Reif A. Expressional profile of the diacylglycerol kinase eta gene DGKH. European Archives of Psychiatry and Clinical Neuroscience. PMID 27085324 DOI: 10.1007/S00406-016-0695-4  0.63
2016 Candemir E, Kollert L, Weißflog L, Geis M, Müller A, Post AM, O׳Leary A, Harro J, Reif A, Freudenberg F. Interaction of NOS1AP with the NOS-I PDZ domain: Implications for schizophrenia-related alterations in dendritic morphology. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26861996 DOI: 10.1016/J.Euroneuro.2016.01.008  0.622
2016 Candemir E, Kollert L, Weißflog L, Geis M, Müller A, Post A, O'Leary A, Harro J, Reif A, Freudenberg F. P.1.008 Interaction of nitric oxide synthase 1 with its adaptor protein: effects on schizophrenia-related dendritic alterations European Neuropsychopharmacology. 26: S9-S10. DOI: 10.1016/S0924-977X(16)70011-3  0.585
2016 Candemir E, O’Leary A, Grünewald L, Reif A, Freudenberg F. Anxiogenic effects upon disruption of neuronal nitric oxide synthase postsynaptic density protein 95/discs large 1/zona occludens 1 (PDZ) interaction European Neuropsychopharmacology. 26: S599-S600. DOI: 10.1016/S0924-977X(16)31675-3  0.571
2016 Freudenberg F, Candemir E, O’Leary A, Grünewald L, Schneider M, Reif A. Postsynaptic density protein 95/discs large 1/zona occludens 1 (PDZ) interaction of neuronal nitric oxide synthase in schizophrenia-related behaviours European Neuropsychopharmacology. 26: S573-S574. DOI: 10.1016/S0924-977X(16)31632-7  0.596
2016 Sprengel R, Freudenberg F. A tribute to Peter H. Seeburg (8.21.1944–8.22.2016) Neurobiology of Learning and Memory. 136: A1-A2. DOI: 10.1016/J.Nlm.2016.11.001  0.442
2015 Freudenberg F, Carreño Gutierrez H, Post AM, Reif A, Norton WH. Aggression in non-human vertebrates: Genetic mechanisms and molecular pathways. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 26284957 DOI: 10.1002/Ajmg.B.32358  0.576
2015 Weber H, Kittel-Schneider S, Heupel J, Weißflog L, Kent L, Freudenberg F, Alttoa A, Post A, Herterich S, Haavik J, Halmøy A, Fasmer OB, Landaas ET, Johansson S, Cormand B, et al. On the role of NOS1 ex1f-VNTR in ADHD-allelic, subgroup, and meta-analysis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 26086921 DOI: 10.1002/Ajmg.B.32326  0.584
2015 Freudenberg F, Celikel T, Reif A. The role of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in depression: central mediators of pathophysiology and antidepressant activity? Neuroscience and Biobehavioral Reviews. 52: 193-206. PMID 25783220 DOI: 10.1016/J.Neubiorev.2015.03.005  0.703
2015 Freudenberg F, Alttoa A, Reif A. Neuronal nitric oxide synthase (NOS1) and its adaptor, NOS1AP, as a genetic risk factors for psychiatric disorders. Genes, Brain, and Behavior. 14: 46-63. PMID 25612209 DOI: 10.1111/Gbb.12193  0.649
2014 Vied CM, Freudenberg F, Wang Y, Raposo AA, Feng D, Nowakowski RS. A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development. Frontiers in Neuroscience. 8: 257. PMID 25191221 DOI: 10.3389/Fnins.2014.00257  0.316
2014 Weber H, Klamer D, Freudenberg F, Kittel-Schneider S, Rivero O, Scholz CJ, Volkert J, Kopf J, Heupel J, Herterich S, Adolfsson R, Alttoa A, Post A, Grußendorf H, Kramer A, et al. The genetic contribution of the NO system at the glutamatergic post-synapse to schizophrenia: further evidence and meta-analysis. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 65-85. PMID 24220657 DOI: 10.1016/J.Euroneuro.2013.09.005  0.633
2014 Freudenberg F, Kollert L, Candemir E, Töpner T, Geis M, Müller A, Weissflog L, Reif A. P.3.a.007 The interaction between NOS-I and NOS1AP in dendrite development: implications for schizophrenia European Neuropsychopharmacology. 24: S487-S488. DOI: 10.1016/S0924-977X(14)70780-1  0.57
2014 Post A, Popp S, Töpner T, Weissflog L, Candemir E, Freudenberg F, Haaf T, Reif A. P.1.h.016 Behavioural consequences of prenatal environmental enrichment in CD1 mice: relevance for the etiology of psychiatric disorders European Neuropsychopharmacology. 24: S279. DOI: 10.1016/S0924-977X(14)70440-7  0.571
2014 Weissflog L, Freudenberg F, Schartner C, Weber H, Scholz C, Reif A. P.1.a.009 GTP-binding protein Di-Ras2 (Diras2) knockdown studies in murine hippocampal primary cells European Neuropsychopharmacology. 24: S158. DOI: 10.1016/S0924-977X(14)70240-8  0.532
2013 Freudenberg F, Marx V, Seeburg PH, Sprengel R, Celikel T. Circuit mechanisms of GluA1-dependent spatial working memory. Hippocampus. 23: 1359-66. PMID 23929622 DOI: 10.1002/Hipo.22184  0.745
2013 Freudenberg F, Marx V, Mack V, Layer LE, Klugmann M, Seeburg PH, Sprengel R, Celikel T. GluA1 and its PDZ-interaction: a role in experience-dependent behavioral plasticity in the forced swim test. Neurobiology of Disease. 52: 160-7. PMID 23262314 DOI: 10.1016/J.Nbd.2012.12.003  0.744
2013 Freudenberg F, Marx V, Mack V, Layer L, Klugmann M, Seeburg P, Sprengel R, Celikel T. S.12.04 Targeting postsynaptic density protein 95(PSD-95)/Discs large/Zonula occludens-1 (PDZ)-interactions of the glutamatergic synapse in animal models of depression European Neuropsychopharmacology. 23: S129-S130. DOI: 10.1016/S0924-977X(13)70170-6  0.729
2013 Freudenberg F, Marx V, Mack V, Layer L, Klugmann M, Seeburg P, Sprengel R, Celikel T. P.2.011 GluA1 and its Postsynaptic density protein 95 (PSD-95)/Discs large/Zonula occludens-1 (PDZ)-interaction: a role in experience-dependent behavioural plasticity in the forced swim test European Neuropsychopharmacology. 23: S35-S36. DOI: 10.1016/S0924-977X(13)70039-7  0.703
2007 Celikel T, Marx V, Freudenberg F, Zivkovic A, Resnik E, Hasan MT, Licznerski P, Osten P, Rozov A, Seeburg PH, Schwarz MK. Select overexpression of homer1a in dorsal hippocampus impairs spatial working memory. Frontiers in Neuroscience. 1: 97-110. PMID 18982121 DOI: 10.3389/Neuro.01.1.1.007.2007  0.761
2007 Schwabe K, Freudenberg F, Koch M. Selective breeding of reduced sensorimotor gating in Wistar rats. Behavior Genetics. 37: 706-12. PMID 17899353 DOI: 10.1007/S10519-007-9166-Z  0.472
2007 Dieckmann M, Freudenberg F, Klein S, Koch M, Schwabe K. Disturbed social behavior and motivation in rats selectively bred for deficient sensorimotor gating. Schizophrenia Research. 97: 250-3. PMID 17855056 DOI: 10.1016/J.Schres.2007.08.007  0.445
2007 Freudenberg F, Dieckmann M, Winter S, Koch M, Schwabe K. Selective breeding for deficient sensorimotor gating is accompanied by increased perseveration in rats. Neuroscience. 148: 612-22. PMID 17693035 DOI: 10.1016/J.Neuroscience.2007.06.034  0.467
2004 Cetin T, Freudenberg F, Füchtemeier M, Koch M. Dopamine in the orbitofrontal cortex regulates operant responding under a progressive ratio of reinforcement in rats. Neuroscience Letters. 370: 114-7. PMID 15488305 DOI: 10.1016/J.Neulet.2004.08.002  0.415
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