John R. Bethea, PhD - Related publications

Affiliations: 
Neurological Surgery University of Miami Miller School of Medicine, Miami, FL, United States 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Sîrbulescu RF, Mamidi A, Chan SC, Jin G, Boukhali M, Sobell D, Ilieş I, Chung JY, Haas W, Whalen MJ, Sluder AE, Poznansky MC. B cells support the repair of injured tissues by adopting MyD88-dependent regulatory functions and phenotype. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e22019. PMID 34792819 DOI: 10.1096/fj.202101095RR   
2021 Xie X, Xiao Y, Xu K. Mechanism underlying circularRNA_014301-mediated regulation of neuronal cell inflammation and apoptosis. Experimental and Therapeutic Medicine. 22: 1432. PMID 34707713 DOI: 10.3892/etm.2021.10867   
2021 Wu XF, Li C, Yang G, Wang YZ, Peng Y, Zhu DD, Sui AR, Wu Q, Li QF, Wang B, Li N, Zhang Y, Ge BY, Zhao J, Li S. Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation. Frontiers in Pharmacology. 12: 704715. PMID 34675802 DOI: 10.3389/fphar.2021.704715   
2021 Izrael M, Molakandov K, Revel A, Slutsky SG, Sonnenfeld T, Weiss JM, Revel M. Astrocytes Downregulate Inflammation in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome: Applicability to COVID-19. Frontiers in Medicine. 8: 740071. PMID 34778302 DOI: 10.3389/fmed.2021.740071   
2021 Wang J, Shi K, Li S, Chen L, Liu W, Wu X, Shen Y, Sun Y, Cheng J, Wu X, Xu Q. Meisoindigo attenuates dextran sulfate sodium-induced experimental colitis via its inhibition of TAK1 in macrophages. International Immunopharmacology. 101: 108239. PMID 34653728 DOI: 10.1016/j.intimp.2021.108239   
2021 Xie L, Saimaier K, Wang C, Yang J, Han M, Lv J, Zhuang W, Liu G, Du C. Methyl acetate arrests Th1 in peripheral immune system and alleviates CNS inflammation in EAE. International Immunopharmacology. 108291. PMID 34799286 DOI: 10.1016/j.intimp.2021.108291   
2021 Zhang B, Lian W, Zhao J, Wang Z, Liu A, Du G. DL0410 Alleviates Memory Impairment in D-Galactose-Induced Aging Rats by Suppressing Neuroinflammation via the TLR4/MyD88/NF-B Pathway. Oxidative Medicine and Cellular Longevity. 2021: 6521146. PMID 34650664 DOI: 10.1155/2021/6521146   
2021 Bian HJ, Xu SY, Li HQ, Jia JQ, Ye L, Shu S, Xia SN, Gu Y, Zhu X, Xu Y, Cao X. JLX001 ameliorates cerebral ischemia injury by modulating microglial polarization and compromising NLRP3 inflammasome activation via the NF-κB signaling pathway. International Immunopharmacology. 101: 108325. PMID 34740080 DOI: 10.1016/j.intimp.2021.108325   
2021 Li Y, Li B, Wang P, Wang Q. Traditional Chinese Medicine, Qingfei Paidu Decoction and Xuanfei Baidu Decoction, Inhibited Cytokine Production NF-κB Signaling Pathway in Macrophages: Implications for Coronavirus Disease 2019 (COVID-19) Therapy. Frontiers in Pharmacology. 12: 722126. PMID 34764867 DOI: 10.3389/fphar.2021.722126   
2021 Kan X, Chen Y, Huang B, Fu S, Guo W, Ran X, Cao Y, Xu D, Cheng J, Yang Z, Xu Y. ‍. Journal of Zhejiang University. Science. B. 22: 929-940. PMID 34783223 DOI: 10.1631/jzus.B2000583   
2021 Yang P, Chen L, Shi Y, Zhou F, Tian H, Li J, Gao L. Progesterone alters the activation and typing of the microglia in the optic nerve crush model. Experimental Eye Research. 108805. PMID 34699875 DOI: 10.1016/j.exer.2021.108805   
2021 Zhao L, Tao X, Song T. Astaxanthin alleviates neuropathic pain by inhibiting the MAPKs and NF-κB pathways. European Journal of Pharmacology. 912: 174575. PMID 34673033 DOI: 10.1016/j.ejphar.2021.174575   
2021 Chen IC, Wang SC, Chen YT, Tseng HH, Liu PL, Lin TC, Wu HE, Chen YR, Tseng YH, Hsu JH, Dai ZK, Suen JL, Li CY. Corylin Ameliorates LPS-Induced Acute Lung Injury via Suppressing the MAPKs and IL-6/STAT3 Signaling Pathways. Pharmaceuticals (Basel, Switzerland). 14. PMID 34681270 DOI: 10.3390/ph14101046   
2021 Feng D, Yu J, Bao L, Fan D, Zhang B. Inhibiting RGS1 attenuates secondary inflammation response and tissue degradation via the TLR/TRIF/NF-κB pathway in macrophage post spinal cord injury. Neuroscience Letters. 136374. PMID 34852285 DOI: 10.1016/j.neulet.2021.136374   
2021 Wu Q, Wang Y, Li Q. Matairesinol exerts anti-inflammatory and antioxidant effects in sepsis-mediated brain injury by repressing the MAPK and NF-κB pathways through up-regulating AMPK. Aging. 13. PMID 34705665 DOI: 10.18632/aging.   
2021 Shen W, Yin Y, Li T, Cao G. Euxanthone inhibits lipopolysaccharide-induced injury, inflammatory response, and MUC5AC hypersecretion in human airway epithelial cells by the TLR4/MyD88 pathway. Journal of Applied Toxicology : Jat. PMID 34655103 DOI: 10.1002/jat.4249   
2021 An N, Yang T, Zhang XX, Xu MX. Bergamottin alleviates LPS-induced acute lung injury by inducing SIRT1 and suppressing NF-κB. Innate Immunity. 17534259211062553. PMID 34812690 DOI: 10.1177/17534259211062553   
2021 Jia J, Zhang P, Zhang C, Jiang G, Zheng W, Song S, Ai C. Sulfated polysaccharides from pacific abalone attenuated DSS-induced acute and chronic ulcerative colitis in mice regulating intestinal micro-ecology and the NF-κB pathway. Food & Function. PMID 34668909 DOI: 10.1039/d1fo02431k   
2021 Dai S, Ye B, Zhong L, Chen Y, Hong G, Zhao G, Su L, Lu Z. GSDMD Mediates LPS-Induced Septic Myocardial Dysfunction by Regulating ROS-dependent NLRP3 Inflammasome Activation. Frontiers in Cell and Developmental Biology. 9: 779432. PMID 34820388 DOI: 10.3389/fcell.2021.779432   
2021 Mai C, Qiu L, Zeng Y, He Y. Yunnan Black Tea Flavonoids Can Improve Cognitive Dysfunction in Septic Mice by Activating SIRT1. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 5775040. PMID 34721636 DOI: 10.1155/2021/5775040   
2021 Deng L, Cheng S, Li J, Xu X, Hao X, Fan Y, Mu S. Synthesis and biological evaluation of novel schisanhenol derivatives as potential hepatoprotective agents. European Journal of Medicinal Chemistry. 227: 113919. PMID 34688010 DOI: 10.1016/j.ejmech.2021.113919   
2021 Chauhan P, Sheng WS, Hu S, Prasad S, Lokensgard JR. Differential Cytokine-Induced Responses of Polarized Microglia. Brain Sciences. 11. PMID 34827481 DOI: 10.3390/brainsci11111482   
2021 Ji M, Sun Q, Zhang G, Zhang Y, Huang Z, Shen Q, Guan H. Microglia-derived TNF-α mediates Müller cell activation by activating the TNFR1-NF-κB pathway. Experimental Eye Research. 108852. PMID 34801535 DOI: 10.1016/j.exer.2021.108852   
2021 Liu FJ, Gu TJ, Wei DY. Emodin alleviates sepsis-mediated lung injury via inhibition and reduction of NF-kB and HMGB1 pathways mediated by SIRT1. The Kaohsiung Journal of Medical Sciences. PMID 34806822 DOI: 10.1002/kjm2.12476   
2021 Wu TJ, Hsieh YJ, Lu CW, Lee CJ, Hsu BG. Linagliptin Protects against Endotoxin-Induced Acute Kidney Injury in Rats by Decreasing Inflammatory Cytokines and Reactive Oxygen Species. International Journal of Molecular Sciences. 22. PMID 34681847 DOI: 10.3390/ijms222011190   
2021 Brickey WJ, Thompson MA, Sheng Z, Li Z, Owzar K, Ting JPY. Re-Examination of the Exacerbating Effect of Inflammasome Components during Radiation Injury. Radiation Research. PMID 34855933 DOI: 10.1667/RADE-21-00142.1   
2021 Chen X, Sun W, Xu B, Wu E, Cui Y, Hao K, Zhang G, Zhou C, Xu Y, Li J, Si H. Polysaccharides From the Roots of Champ Modulate Gut Health and Ameliorate Cyclophosphamide-Induced Intestinal Injury and Immunosuppression. Frontiers in Immunology. 12: 766296. PMID 34745141 DOI: 10.3389/fimmu.2021.766296   
2021 Dhapola R, Hota SS, Sarma P, Bhattacharyya A, Medhi B, Reddy DH. Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer's disease. Inflammopharmacology. PMID 34813026 DOI: 10.1007/s10787-021-00889-6   
2021 Rojo JM, Montes-Casado M, Aragoneses-Fenoll L, Ojeda G, Dianzani U, Portolés P. PI3-Kinase p110α Deficiency Modulates T Cell Homeostasis and Function and Attenuates Experimental Allergic Encephalitis in Mature Mice. International Journal of Molecular Sciences. 22. PMID 34445401 DOI: 10.3390/ijms22168698   
2021 Lin X, Zhu Y, Le G. Tetramethylpyrazine Alleviates Tight Junction Disruption of Bronchial Mucosal Epithelial Cells Caused by Interleukin-17 via Inhibiting Nuclear Factor-κB-p65/Tumor Necrosis Factor-α Signaling Pathway. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. PMID 34698528 DOI: 10.1089/jir.2021.0083   
2021 Chiu LC, Wang JY, Lin CH, Hsu CH, Lin LC, Fu SL. Diterpenoid Compounds Isolated from Solms Exert Anti-Inflammatory Effects by Inhibiting the IKK/NF-κB Pathway. Molecules (Basel, Switzerland). 26. PMID 34770952 DOI: 10.3390/molecules26216540   
2021 Liu X, Zhang X, Niu X, Zhang P, Wang Q, Xue X, Song G, Yu J, Xi G, Song L, Li Y, Ma C. Mdivi-1 Modulates Macrophage/Microglial Polarization in Mice with EAE via the Inhibition of the TLR2/4-GSK3β-NF-κB Inflammatory Signaling Axis. Molecular Neurobiology. PMID 34618332 DOI: 10.1007/s12035-021-02552-1   
2021 Luo Y, Zheng D, Mou T, Pu J, Huang Z, Chen W, Zhang Y, Wu Z. CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway. Experimental and Therapeutic Medicine. 22: 1358. PMID 34659504 DOI: 10.3892/etm.2021.10793   
2021 Ding Z, Cheng R, Yang Y, Zhao Y, Ge W, Sun X, Xu X, Wang S, Zhang J. The succinoglycan riclin restores beta cell function through the regulation of macrophages on Th1 and Th2 differentiation in type 1 diabetic mice. Food & Function. PMID 34714317 DOI: 10.1039/d1fo02315b   
2021 Chen W, Xing J, Liu X, Wang S, Xing D. The role and transformative potential of IL-19 in atherosclerosis. Cytokine & Growth Factor Reviews. PMID 34600839 DOI: 10.1016/j.cytogfr.2021.09.001   
2021 Ahuja S, Lazar IM. Systems-Level Proteomics Evaluation of Microglia Response to Tumor-Supportive Anti-Inflammatory Cytokines. Frontiers in Immunology. 12: 646043. PMID 34566949 DOI: 10.3389/fimmu.2021.646043   
2021 Peng H, Harvey BT, Richards CI, Nixon K. Neuron-Derived Extracellular Vesicles Modulate Microglia Activation and Function. Biology. 10. PMID 34681047 DOI: 10.3390/biology10100948   
2021 Wang C, Yang J, Xie L, Saimaier K, Zhuang W, Han M, Liu G, Lv J, Shi G, Li N, Du C. Methyl Butyrate Alleviates Experimental Autoimmune Encephalomyelitis and Regulates the Balance of Effector T Cells and Regulatory T Cells. Inflammation. PMID 34786625 DOI: 10.1007/s10753-021-01596-8   
2021 Han Y, Lu Y, Li X, Niu X, Chang AK, Yang Z, Li X, He X, Bi X. Novel organoselenides (NSAIDs-Se derivatives) protect against LPS-induced inflammation in microglia by targeting the NOX2/NLRP3 signaling pathway. International Immunopharmacology. 108377. PMID 34836795 DOI: 10.1016/j.intimp.2021.108377   
2021 Hajjar S, Nathan N, Joseph J, Mottawea W, Ariana A, Pyatibrat S, Harper ME, Alain T, Blais A, Russell RC, Sad S. Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10 model of colitis. Cell Death and Differentiation. PMID 34588632 DOI: 10.1038/s41418-021-00876-y   
2021 Wei H, Zhen L, Wang S, Zhang Y, Wang K, Jia P, Zhang Y, Wu Z, Yang Q, Hou W, Lv J, Zhang P. De novo lipogenesis in astrocytes promotes the repair of blood-brain barrier after transient cerebral ischemia through interleukin-33. Neuroscience. PMID 34822949 DOI: 10.1016/j.neuroscience.2021.11.026   
2021 Zhao Z, Yang J, Zhang L, Zhou Y. Enhancement of DUSP14 (dual specificity phosphatase 14) limits osteoarthritis progression by alleviating chondrocyte injury, inflammation and metabolic homeostasis. Bioengineered. 12: 7495-7507. PMID 34605731 DOI: 10.1080/21655979.2021.1979355   
2021 Zhang Q, Feng A, Zeng M, Zhang B, Shi J, Lv Y, Cao B, Zhao C, Wang M, Ding Y, Zheng X. Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways. Innate Immunity. 17534259211051069. PMID 34806444 DOI: 10.1177/17534259211051069   
2021 Ueno T, Yamamoto Y, Kawasaki K. Phagocytosis of microparticles increases responsiveness of macrophage-like cell lines U937 and THP-1 to bacterial lipopolysaccharide and lipopeptide. Scientific Reports. 11: 6782. PMID 33762618 DOI: 10.1038/s41598-021-86202-5   
2021 No H, Nam SH, Seo HW, Seo J, Park SH, Kim SB, Jung JS, Park J, Choi J, Lee JY, Suh HW, Lim SS, Kim JK. Purple corn extract alleviates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like phenotypes in BALB/c mice. Animal Cells and Systems. 25: 272-282. PMID 34745434 DOI: 10.1080/19768354.2021.1974938   
2021 Shaheen MJ, Bekdash AM, Itani HA, Borjac JM. Saffron extract attenuates neuroinflammation in rmTBI mouse model by suppressing NLRP3 inflammasome activation via SIRT1. Plos One. 16: e0257211. PMID 34506597 DOI: 10.1371/journal.pone.0257211   
2021 Bao X, Chen C, Yuan L. Triptolide Attenuates Neuropathic Pain by Regulating Microglia Polarization through the CCL2/CCR2 Axis. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 8985721. PMID 34691228 DOI: 10.1155/2021/8985721   
2021 Casadei M, Fiore E, Rubione J, Domínguez LM, Coronel MF, Leiguarda C, García M, Mazzolini G, Villar MJ, Montaner A, Constandil L, Romero-Sandoval EA, Brumovsky PR. IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injured nerve. Pain. PMID 34711765 DOI: 10.1097/j.pain.0000000000002476   
2021 Lee HS, Paik JH, Kwon OK, Paryanto I, Yuniato P, Ryu HW, Choi SH, Oh SR, Han SB, Park JW, Ahn KS. Anti-Inflammatory Effects of Teijsm. & Binn. in TNF/IFN-Stimulated Keratinocytes. Evidence-Based Complementary and Alternative Medicine : Ecam. 2021: 2439231. PMID 34795780 DOI: 10.1155/2021/2439231   
2021 Deng F, Hu JJ, Yang X, Sun QS, Lin ZB, Zhao BC, Yao ZW, Luo SD, Chen ZL, Liu Y, Yan ZZ, Li C, Liu WF, Liu KX. Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells IL-33/ST2 Signaling. Frontiers in Immunology. 12: 704836. PMID 34650552 DOI: 10.3389/fimmu.2021.704836