Royce H. Adams, Ph.D. - Publications

Affiliations: 
2007 University of South Carolina, Columbia, SC 
Area:
Health Care Management

115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Le Mercier A, Bonnavion R, Yu W, Alnouri MW, Ramas S, Zhang Y, Jäger Y, Roquid KA, Jeong HW, Sivaraj KK, Cho H, Chen X, Strilic B, Sijmonsma T, Adams R, et al. GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33875597 DOI: 10.1073/pnas.2021596118  0.34
2020 Hong SP, Yang MJ, Cho H, Park I, Bae H, Choe K, Suh SH, Adams RH, Alitalo K, Lim D, Koh GY. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi. Nature Communications. 11: 4102. PMID 32796823 DOI: 10.1038/S41467-020-17886-Y  0.309
2020 Brulois K, Rajaraman A, Szade A, Nordling S, Bogoslowski A, Dermadi D, Rahman M, Kiefel H, O'Hara E, Koning JJ, Kawashima H, Zhou B, Vestweber D, Red-Horse K, Mebius RE, ... Adams RH, et al. A molecular map of murine lymph node blood vascular endothelium at single cell resolution. Nature Communications. 11: 3798. PMID 32732867 DOI: 10.1038/s41467-020-17291-5  0.31
2020 Ma X, Uchida Y, Wei T, Liu C, Adams RH, Kubota Y, Gutkind JS, Mukouyama YS, Adelstein RS. Nonmuscle Myosin 2 Regulates Cortical Stability during Sprouting Angiogenesis. Molecular Biology of the Cell. mbcE20030175. PMID 32583739 DOI: 10.1091/Mbc.E20-03-0175  0.37
2020 Figueiredo AM, Villacampa P, Diéguez-Hurtado R, Lozano JJ, Kobialka P, Cortazar AR, Martinez-Romero A, Angulo-Urarte A, Franco CA, Claret M, Aransay AM, Adams RH, Carracedo A, Graupera M. PI3Kβ-Regulated Pericyte Maturation Governs Vascular Remodeling. Circulation. PMID 32466671 DOI: 10.1161/CIRCULATIONAHA.119.042354  0.432
2020 Jiang H, Zhang L, Liu X, Sun W, Kato K, Chen C, Li X, Li T, Sun Z, Han W, Zhang F, Xiao Q, Yang Z, Hu J, Qin Z, ... Adams RH, et al. Angiocrine FSTL1 (Follistatin-Like Protein 1) Insufficiency Leads to Atrial and Venous Wall Fibrosis via SMAD3 Activation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313901. PMID 32078339 DOI: 10.1161/ATVBAHA.119.313901  0.422
2019 Luxán G, Stewen J, Díaz N, Kato K, Maney SK, Aravamudhan A, Berkenfeld F, Nagelmann N, Drexler HC, Zeuschner D, Faber C, Schillers H, Hermann S, Wiseman J, Vaquerizas JM, ... ... Adams RH, et al. Endothelial EphB4 maintains vascular integrity and transport function in adult heart. Elife. 8. PMID 31782728 DOI: 10.7554/eLife.45863  0.35
2019 Chen Q, Liu Y, Jeong HW, Stehling M, Dinh VV, Zhou B, Adams RH. Apelin Endothelial Niche Cells Control Hematopoiesis and Mediate Vascular Regeneration after Myeloablative Injury. Cell Stem Cell. PMID 31761723 DOI: 10.1016/j.stem.2019.10.006  0.358
2019 Park H, Yamamoto H, Mohn L, Ambühl L, Kanai K, Schmidt I, Kim KP, Fraccaroli A, Feil S, Junge HJ, Montanez E, Berger W, Adams RH. Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy. Nature Communications. 10: 5243. PMID 31748531 DOI: 10.1038/S41467-019-13220-3  0.323
2019 Tisch N, Freire-Valls A, Yerbes R, Paredes I, La Porta S, Wang X, Martín-Pérez R, Castro L, Wong WW, Coultas L, Strilic B, Gröne HJ, Hielscher T, Mogler C, Adams R, et al. Caspase-8 modulates physiological and pathological angiogenesis during retina development. The Journal of Clinical Investigation. PMID 31454332 DOI: 10.1172/JCI122767  0.378
2019 Diéguez-Hurtado R, Kato K, Giaimo BD, Nieminen-Kelhä M, Arf H, Ferrante F, Bartkuhn M, Zimmermann T, Bixel MG, Eilken HM, Adams S, Borggrefe T, Vajkoczy P, Adams RH. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nature Communications. 10: 2817. PMID 31249304 DOI: 10.1038/s41467-019-10643-w  0.312
2019 Jensen LD, Hot B, Ramsköld D, Germano RFV, Yokota C, Giatrellis S, Lauschke VM, Hubmacher D, Li MX, Hupe M, Arnold TD, Sandberg R, Frisén J, Trusohamn M, Martowicz A, ... ... Adams RH, et al. Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of β-Catenin Signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 1432-1447. PMID 31242033 DOI: 10.1161/Atvbaha.119.312388  0.338
2019 Benz F, Wichitnaowarat V, Lehmann M, Germano RFV, Mihova D, Macas J, Adams RH, Taketo MM, Guérit S, Plate KH, Vanhollebeke B, Liebner S. Low Wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice. Elife. 8. PMID 30932814 DOI: 10.7554/eLife.43818  0.348
2019 Boriushkin E, Zhang H, Becker M, Peachey J, Shatat MA, Adams RH, Hamik A. Kruppel-like factor 4 regulates developmental angiogenesis through disruption of the RBP-J-NICD-MAML complex in intron 3 of Dll4. Angiogenesis. PMID 30607695 DOI: 10.1007/s10456-018-9657-y  0.409
2019 Sivaraj KK, Dharmalingam B, Mohanakrishnan V, Jeong H, Kato K, Schröder S, Adams S, Koh GY, Adams RH. Author response: YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells Elife. DOI: 10.7554/Elife.50770.Sa2  0.328
2018 Zhang C, Lai MB, Pedler MG, Johnson V, Adams RH, Petrash JM, Chen Z, Junge HJ. Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 2691-2705. PMID 30354230 DOI: 10.1161/Atvbaha.118.311689  0.443
2018 Dubrac A, Künzel SE, Künzel SH, Li J, Chandran RR, Martin K, Greif DM, Adams RH, Eichmann A. NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy. Nature Communications. 9: 3463. PMID 30150707 DOI: 10.1038/s41467-018-05926-7  0.377
2018 Seynhaeve ALB, Oostinga D, van Haperen R, Eilken HM, Adams S, Adams RH, Ten Hagen TLM. Spatiotemporal endothelial cell - pericyte association in tumors as shown by high resolution 4D intravital imaging. Scientific Reports. 8: 9596. PMID 29941944 DOI: 10.1038/s41598-018-27943-8  0.378
2018 Kato K, Diéguez-Hurtado R, Park DY, Hong SP, Kato-Azuma S, Adams S, Stehling M, Trappmann B, Wrana JL, Koh GY, Adams RH. Pulmonary pericytes regulate lung morphogenesis. Nature Communications. 9: 2448. PMID 29934496 DOI: 10.1038/s41467-018-04913-2  0.382
2018 Špiranec K, Chen W, Werner F, Nikolaev VO, Naruke T, Koch F, Werner A, Eder-Negrin P, Diéguez-Hurtado R, Adams RH, Baba HA, Schmidt H, Schuh K, Skryabin BV, Movahedi K, et al. Endothelial C-Type Natriuretic Peptide Acts on Pericytes to Regulate Microcirculatory Flow and Blood Pressure. Circulation. PMID 29626067 DOI: 10.1161/Circulationaha.117.033383  0.373
2018 La Porta S, Roth L, Singhal M, Mogler C, Spegg C, Schieb B, Qu X, Adams RH, Baldwin HS, Savant S, Augustin HG. Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis. The Journal of Clinical Investigation. PMID 29355844 DOI: 10.1172/Jci94674  0.319
2018 Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, ... ... Adams RH, et al. Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart. Circulation. PMID 29353241 DOI: 10.1161/Circulationaha.117.029733  0.318
2017 Duarte D, Hawkins ED, Akinduro O, Ang H, De Filippo K, Kong IY, Haltalli M, Ruivo N, Straszkowski L, Vervoort SJ, McLean C, Weber TS, Khorshed R, Pirillo C, Wei A, ... ... Adams RH, et al. Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML. Cell Stem Cell. PMID 29276143 DOI: 10.1016/J.Stem.2017.11.006  0.347
2017 Cao J, Ehling M, März S, Seebach J, Tarbashevich K, Sixta T, Pitulescu ME, Werner AC, Flach B, Montanez E, Raz E, Adams RH, Schnittler H. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis. Nature Communications. 8: 2210. PMID 29263363 DOI: 10.1038/s41467-017-02373-8  0.327
2017 Eilken HM, Diéguez-Hurtado R, Schmidt I, Nakayama M, Jeong HW, Arf H, Adams S, Ferrara N, Adams RH. Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1. Nature Communications. 8: 1574. PMID 29146905 DOI: 10.1038/s41467-017-01738-3  0.415
2017 Jeong HW, Hernández-Rodríguez B, Kim J, Kim KP, Enriquez-Gasca R, Yoon J, Adams S, Schöler HR, Vaquerizas JM, Adams RH. Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis. Nature Communications. 8: 726. PMID 28959057 DOI: 10.1038/s41467-017-00738-7  0.381
2017 Watson EC, Adams RH. Biology of Bone: The Vasculature of the Skeletal System. Cold Spring Harbor Perspectives in Medicine. PMID 28893838 DOI: 10.1101/cshperspect.a031559  0.371
2017 Zhong W, Gao X, Wang S, Han K, Ema M, Adams S, Adams RH, Rosenblatt MI, Chang JH, Azar DT. Prox1-GFP/Flt1-DsRed transgenic mice: an animal model for simultaneous live imaging of angiogenesis and lymphangiogenesis. Angiogenesis. PMID 28795242 DOI: 10.1007/s10456-017-9572-7  0.438
2017 Pitulescu ME, Schmidt I, Giaimo BD, Antoine T, Berkenfeld F, Ferrante F, Park H, Ehling M, Biljes D, Rocha SF, Langen UH, Stehling M, Nagasawa T, Ferrara N, Borggrefe T, ... Adams RH, et al. Dll4 and Notch signalling couples sprouting angiogenesis and artery formation. Nature Cell Biology. PMID 28714968 DOI: 10.1038/ncb3555  0.459
2017 Shah AV, Birdsey GM, Peghaire C, Pitulescu ME, Dufton NP, Yang Y, Weinberg I, Osuna Almagro L, Payne L, Mason JC, Gerhardt H, Adams RH, Randi AM. The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability. Nature Communications. 8: 16002. PMID 28695891 DOI: 10.1038/ncomms16002  0.321
2017 Park DY, Lee J, Kim J, Kim K, Hong S, Han S, Kubota Y, Augustin HG, Ding L, Kim JW, Kim H, He Y, Adams RH, Koh GY. Plastic roles of pericytes in the blood-retinal barrier. Nature Communications. 8: 15296. PMID 28508859 DOI: 10.1038/Ncomms15296  0.37
2017 Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Häger C, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, ... ... Adams RH, et al. Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling. Nature Communications. 8: 15486. PMID 28466869 DOI: 10.1038/ncomms15486  0.324
2017 Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH. Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nature Cell Biology. PMID 28218908 DOI: 10.1038/ncb3476  0.401
2016 Chu M, Li T, Shen B, Cao X, Zhong H, Zhang L, Zhou F, Ma W, Jiang H, Xie P, Liu Z, Dong N, Xu Y, Zhao Y, Xu G, ... ... Adams RH, et al. Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII. Elife. 5. PMID 28005008 DOI: 10.7554/Elife.21032  0.397
2016 Ramasamy SK, Kusumbe AP, Schiller M, Zeuschner D, Bixel MG, Milia C, Gamrekelashvili J, Limbourg A, Medvinsky A, Santoro MM, Limbourg FP, Adams RH. Blood flow controls bone vascular function and osteogenesis. Nature Communications. 7: 13601. PMID 27922003 DOI: 10.1038/ncomms13601  0.353
2016 Mondor I, Jorquera A, Sene C, Adriouch S, Adams RH, Zhou B, Wienert S, Klauschen F, Bajénoff M. Clonal Proliferation and Stochastic Pruning Orchestrate Lymph Node Vasculature Remodeling. Immunity. 45: 877-888. PMID 27760341 DOI: 10.1016/j.immuni.2016.09.017  0.366
2016 Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, ... ... Adams RH, et al. Regulation of monocyte cell fate by blood vessels mediated by Notch signalling. Nature Communications. 7: 12597. PMID 27576369 DOI: 10.1038/ncomms12597  0.424
2016 Ramasamy SK, Kusumbe AP, Itkin T, Gur-Cohen S, Lapidot T, Adams RH. Regulation of Hematopoiesis and Osteogenesis by Blood Vessel-Derived Signals. Annual Review of Cell and Developmental Biology. PMID 27576121 DOI: 10.1146/Annurev-Cellbio-111315-124936  0.348
2016 Chen Q, Zhang H, Liu Y, Adams S, Eilken H, Stehling M, Corada M, Dejana E, Zhou B, Adams RH. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells. Nature Communications. 7: 12422. PMID 27516371 DOI: 10.1038/ncomms12422  0.398
2016 Gao F, Artham S, Sabbineni H, Al-Azayzih A, Peng XD, Hay N, Adams RH, Byzova TV, Somanath PR. Akt1 promotes stimuli-induced endothelial-barrier protection through FoxO-mediated tight-junction protein turnover. Cellular and Molecular Life Sciences : Cmls. PMID 27113546 DOI: 10.1007/S00018-016-2232-Z  0.397
2016 Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, Butler JM, ... ... Adams RH, et al. Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. PMID 27074509 DOI: 10.1038/Nature17624  0.303
2016 Kusumbe AP, Ramasamy SK, Itkin T, Mäe MA, Langen UH, Betsholtz C, Lapidot T, Adams RH. Age-dependent modulation of vascular niches for haematopoietic stem cells. Nature. PMID 27074508 DOI: 10.1038/Nature17638  0.407
2016 Kerr BA, West XZ, Kim YW, Zhao Y, Tischenko M, Cull RM, Phares TW, Peng XD, Bernier-Latmani J, Petrova TV, Adams RH, Hay N, Naga Prasad SV, Byzova TV. Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium. Nature Communications. 7: 10960. PMID 26971877 DOI: 10.1038/Ncomms10960  0.421
2016 Watson EC, Whitehead L, Adams RH, Dewson G, Coultas L. Endothelial cell survival during angiogenesis requires the pro-survival protein MCL1. Cell Death and Differentiation. PMID 26943318 DOI: 10.1038/cdd.2016.20  0.365
2016 Nohata N, Uchida Y, Stratman AN, Adams RH, Zheng Y, Weinstein BM, Mukouyama YS, Gutkind JS. Temporal-specific roles of Rac1 during vascular development and retinal angiogenesis. Developmental Biology. PMID 26872874 DOI: 10.1016/j.ydbio.2016.02.005  0.452
2016 Merk H, Zhang S, Lehr T, Müller C, Ulrich M, Bibb JA, Adams RH, Bracher F, Zahler S, Vollmar AM, Liebl J. Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis. Oncotarget. PMID 26755662 DOI: 10.18632/oncotarget.6842  0.302
2015 Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, Morini MF, Maddaluno L, Baeyens N, Adams RH, Jain MK, Owens GK, Schwartz M, Lampugnani MG, Dejana E. KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. Embo Molecular Medicine. PMID 26612856 DOI: 10.15252/Emmm.201505433  0.365
2015 Savant S, La Porta S, Budnik A, Busch K, Hu J, Tisch N, Korn C, Valls AF, Benest AV, Terhardt D, Qu X, Adams RH, Baldwin HS, Ruiz de Almodóvar C, Rodewald HR, et al. The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells. Cell Reports. 12: 1761-73. PMID 26344773 DOI: 10.1016/J.Celrep.2015.08.024  0.419
2015 Weinl C, Castaneda Vega S, Riehle H, Stritt C, Calaminus C, Wolburg H, Mauel S, Breithaupt A, Gruber AD, Wasylyk B, Olson EN, Adams RH, Pichler BJ, Nordheim A. Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke. Proceedings of the National Academy of Sciences of the United States of America. 112: 9914-9. PMID 26221020 DOI: 10.1073/Pnas.1509047112  0.32
2015 Pedrosa AR, Trindade A, Carvalho C, Graça J, Carvalho S, Peleteiro MC, Adams RH, Duarte A. Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions. Oncotarget. PMID 26213336  0.316
2015 Bravi L, Rudini N, Cuttano R, Giampietro C, Maddaluno L, Ferrarini L, Adams RH, Corada M, Boulday G, Tournier-Lasserve E, Dejana E, Lampugnani MG. Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26109568 DOI: 10.1073/pnas.1501352112  0.352
2015 van Lessen M, Nakayama M, Kato K, Kim JM, Kaibuchi K, Adams RH. Regulation of Vascular Endothelial Growth Factor Receptor Function in Angiogenesis by Numb and Numb-Like. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1815-25. PMID 26069237 DOI: 10.1161/Atvbaha.115.305473  0.384
2015 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S. Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nature Communications. 6: 7274. PMID 26027726 DOI: 10.1038/ncomms8274  0.326
2015 Mikelis CM, Simaan M, Ando K, Fukuhara S, Sakurai A, Amornphimoltham P, Masedunskas A, Weigert R, Chavakis T, Adams RH, Offermanns S, Mochizuki N, Zheng Y, Gutkind JS. RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock. Nature Communications. 6: 6725. PMID 25857352 DOI: 10.1038/ncomms7725  0.39
2015 Stanczuk L, Martinez-Corral I, Ulvmar MH, Zhang Y, Laviña B, Fruttiger M, Adams RH, Saur D, Betsholtz C, Ortega S, Alitalo K, Graupera M, Mäkinen T. cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels. Cell Reports. PMID 25772358 DOI: 10.1016/J.Celrep.2015.02.026  0.428
2015 Pedrosa AR, Trindade A, Fernandes AC, Carvalho C, Gigante J, Tavares AT, Diéguez-Hurtado R, Yagita H, Adams RH, Duarte A. Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1134-46. PMID 25767274 DOI: 10.1161/ATVBAHA.114.304741  0.385
2015 Yamamoto H, Ehling M, Kato K, Kanai K, van Lessen M, Frye M, Zeuschner D, Nakayama M, Vestweber D, Adams RH. Integrin β1 controls VE-cadherin localization and blood vessel stability. Nature Communications. 6: 6429. PMID 25752958 DOI: 10.1038/ncomms7429  0.381
2015 Birdsey GM, Shah AV, Dufton N, Reynolds LE, Osuna Almagro L, Yang Y, Aspalter IM, Khan ST, Mason JC, Dejana E, Göttgens B, Hodivala-Dilke K, Gerhardt H, Adams RH, Randi AM. The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling. Developmental Cell. 32: 82-96. PMID 25584796 DOI: 10.1016/j.devcel.2014.11.016  0.39
2015 Ramasamy SK, Kusumbe AP, Adams RH. Regulation of tissue morphogenesis by endothelial cell-derived signals. Trends in Cell Biology. 25: 148-57. PMID 25529933 DOI: 10.1016/j.tcb.2014.11.007  0.409
2015 Pedrosa AR, Trindade A, Carvalho C, Graça J, Carvalho S, Peleteiro MC, Adams RH, Duarte A. Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions Oncotarget. 6: 24404-24423. DOI: 10.18632/oncotarget.4380  0.315
2015 Itkin T, Gur Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Jung Y, Ledergor G, Milo I, Poulos MG, Fernandez MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, ... ... Adams RH, et al. Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells Blood. 126: 664-664. DOI: 10.1182/Blood.V126.23.664.664  0.384
2015 Savant S, LaPorta S, Budnik A, Busch K, Hu J, Tisch N, Korn C, Valls AF, Benest AV, Terhardt D, Qu X, Adams RH, Baldwin HS, RuizdeAlmodóvar C, Rodewald HR, et al. The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells Cell Reports. DOI: 10.1016/j.celrep.2015.08.024  0.365
2014 Xu C, Hasan SS, Schmidt I, Rocha SF, Pitulescu ME, Bussmann J, Meyen D, Raz E, Adams RH, Siekmann AF. Arteries are formed by vein-derived endothelial tip cells. Nature Communications. 5: 5758. PMID 25502622 DOI: 10.1038/ncomms6758  0.386
2014 Pitulescu ME, Adams RH. Regulation of signaling interactions and receptor endocytosis in growing blood vessels. Cell Adhesion & Migration. 8: 366-77. PMID 25482636 DOI: 10.4161/19336918.2014.970010  0.376
2014 Murphy PA, Kim TN, Huang L, Nielsen CM, Lawton MT, Adams RH, Schaffer CB, Wang RA. Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels. Proceedings of the National Academy of Sciences of the United States of America. 111: 18007-12. PMID 25468970 DOI: 10.1073/Pnas.1415316111  0.382
2014 Ottone C, Krusche B, Whitby A, Clements M, Quadrato G, Pitulescu ME, Adams RH, Parrinello S. Direct cell-cell contact with the vascular niche maintains quiescent neural stem cells. Nature Cell Biology. 16: 1045-56. PMID 25283993 DOI: 10.1038/Ncb3045  0.325
2014 Rocha SF, Schiller M, Jing D, Li H, Butz S, Vestweber D, Biljes D, Drexler HC, Nieminen-Kelhä M, Vajkoczy P, Adams S, Benedito R, Adams RH. Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability. Circulation Research. 115: 581-90. PMID 25057127 DOI: 10.1161/CIRCRESAHA.115.304718  0.418
2014 Hultin S, Zheng Y, Mojallal M, Vertuani S, Gentili C, Balland M, Milloud R, Belting HG, Affolter M, Helker CS, Adams RH, Herzog W, Uhlen P, Majumdar A, Holmgren L. AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion. Nature Communications. 5: 3743. PMID 24806444 DOI: 10.1038/Ncomms4743  0.373
2014 Noels H, Zhou B, Tilstam PV, Theelen W, Li X, Pawig L, Schmitz C, Akhtar S, Simsekyilmaz S, Shagdarsuren E, Schober A, Adams RH, Bernhagen J, Liehn EA, Döring Y, et al. Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1209-20. PMID 24723559 DOI: 10.1161/ATVBAHA.113.302878  0.33
2014 Korn C, Scholz B, Hu J, Srivastava K, Wojtarowicz J, Arnsperger T, Adams RH, Boutros M, Augustin HG, Augustin I. Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis. Development (Cambridge, England). 141: 1757-66. PMID 24715464 DOI: 10.1242/dev.104422  0.428
2014 Ramasamy SK, Kusumbe AP, Wang L, Adams RH. Endothelial Notch activity promotes angiogenesis and osteogenesis in bone. Nature. 507: 376-80. PMID 24647000 DOI: 10.1038/nature13146  0.34
2014 Hu J, Popp R, Frömel T, Ehling M, Awwad K, Adams RH, Hammes HP, Fleming I. Müller glia cells regulate Notch signaling and retinal angiogenesis via the generation of 19,20-dihydroxydocosapentaenoic acid. The Journal of Experimental Medicine. 211: 281-95. PMID 24446488 DOI: 10.1084/jem.20131494  0.351
2014 D'Amico G, Korhonen EA, Anisimov A, Zarkada G, Holopainen T, Hägerling R, Kiefer F, Eklund L, Sormunen R, Elamaa H, Brekken RA, Adams RH, Koh GY, Saharinen P, Alitalo K. Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy. The Journal of Clinical Investigation. 124: 824-34. PMID 24430181 DOI: 10.1172/Jci68897  0.345
2014 Tessneer KL, Pasula S, Cai X, Dong Y, McManus J, Liu X, Yu L, Hahn S, Chang B, Chen Y, Griffin C, Xia L, Adams RH, Chen H. Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 331-7. PMID 24311377 DOI: 10.1161/Atvbaha.113.302586  0.42
2014 You WK, Yotsumoto F, Sakimura K, Adams RH, Stallcup WB. NG2 proteoglycan promotes tumor vascularization via integrin-dependent effects on pericyte function. Angiogenesis. 17: 61-76. PMID 23925489 DOI: 10.1007/s10456-013-9378-1  0.428
2013 Nakayama A, Nakayama M, Turner CJ, Höing S, Lepore JJ, Adams RH. Ephrin-B2 controls PDGFRβ internalization and signaling. Genes & Development. 27: 2576-89. PMID 24298057 DOI: 10.1101/gad.224089.113  0.342
2013 Corada M, Orsenigo F, Morini MF, Pitulescu ME, Bhat G, Nyqvist D, Breviario F, Conti V, Briot A, Iruela-Arispe ML, Adams RH, Dejana E. Sox17 is indispensable for acquisition and maintenance of arterial identity. Nature Communications. 4: 2609. PMID 24153254 DOI: 10.1038/Ncomms3609  0.31
2013 Ehling M, Adams S, Benedito R, Adams RH. Notch controls retinal blood vessel maturation and quiescence. Development (Cambridge, England). 140: 3051-61. PMID 23785053 DOI: 10.1242/dev.093351  0.425
2013 Sivaraj KK, Takefuji M, Schmidt I, Adams RH, Offermanns S, Wettschureck N. G13 controls angiogenesis through regulation of VEGFR-2 expression. Developmental Cell. 25: 427-34. PMID 23664862 DOI: 10.1016/j.devcel.2013.04.008  0.364
2013 Weinl C, Riehle H, Park D, Stritt C, Beck S, Huber G, Wolburg H, Olson EN, Seeliger MW, Adams RH, Nordheim A. Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae. The Journal of Clinical Investigation. 123: 2193-206. PMID 23563308 DOI: 10.1172/Jci64201  0.307
2013 Peddibhotla SSD, Brinkmann BF, Kummer D, Tuncay H, Nakayama M, Adams RH, Gerke V, Ebnet K. Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor-specific angiogenic signaling Molecular Biology of the Cell. 24: 933-944. PMID 23389628 DOI: 10.1091/mbc.E12-06-0481  0.314
2013 Koyama T, Ochoa-Callejero L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Iinuma N, Arai T, Yoshizawa T, Iesato Y, Lei Y, Uetake R, Okimura A, Yamauchi A, Tanaka M, Igarashi K, ... ... Adams RH, et al. Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis. Circulation. 127: 842-53. PMID 23355623 DOI: 10.1161/CIRCULATIONAHA.112.000756  0.343
2013 Nakayama M, Nakayama A, van Lessen M, Yamamoto H, Hoffmann S, Drexler HC, Itoh N, Hirose T, Breier G, Vestweber D, Cooper JA, Ohno S, Kaibuchi K, Adams RH. Spatial regulation of VEGF receptor endocytosis in angiogenesis. Nature Cell Biology. 15: 249-60. PMID 23354168 DOI: 10.1038/Ncb2679  0.407
2013 Hägerling R, Pollmann C, Andreas M, Schmidt C, Nurmi H, Adams RH, Alitalo K, Andresen V, Schulte-Merker S, Kiefer F. A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. The Embo Journal. 32: 629-44. PMID 23299940 DOI: 10.1038/Emboj.2012.340  0.396
2013 Wang L, Benedito R, Bixel MG, Zeuschner D, Stehling M, Sävendahl L, Haigh JJ, Snippert H, Clevers H, Breier G, Kiefer F, Adams RH. Identification of a clonally expanding haematopoietic compartment in bone marrow. The Embo Journal. 32: 219-30. PMID 23188081 DOI: 10.1038/Emboj.2012.308  0.305
2012 Yoshioka K, Yoshida K, Cui H, Wakayama T, Takuwa N, Okamoto Y, Du W, Qi X, Asanuma K, Sugihara K, Aki S, Miyazawa H, Biswas K, Nagakura C, Ueno M, ... ... Adams RH, et al. Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function. Nature Medicine. 18: 1560-9. PMID 22983395 DOI: 10.1038/nm.2928  0.419
2012 Gaengel K, Niaudet C, Hagikura K, Laviña B, Siemsen BL, Muhl L, Hofmann JJ, Ebarasi L, Nyström S, Rymo S, Chen LL, Pang MF, Jin Y, Raschperger E, Roswall P, ... ... Adams R, et al. The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2. Developmental Cell. 23: 587-99. PMID 22975327 DOI: 10.1016/J.Devcel.2012.08.005  0.436
2012 Izumi N, Helker C, Ehling M, Behrens A, Herzog W, Adams RH. Fbxw7 controls angiogenesis by regulating endothelial Notch activity. Plos One. 7: e41116. PMID 22848434 DOI: 10.1371/journal.pone.0041116  0.431
2012 Benedito R, Rocha SF, Woeste M, Zamykal M, Radtke F, Casanovas O, Duarte A, Pytowski B, Adams RH. Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling. Nature. 484: 110-4. PMID 22426001 DOI: 10.1038/nature10908  0.42
2012 Cesca F, Yabe A, Spencer-Dene B, Scholz-Starke J, Medrihan L, Maden CH, Gerhardt H, Orriss IR, Baldelli P, Al-Qatari M, Koltzenburg M, Adams RH, Benfenati F, Schiavo G. Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems. Cell Death and Differentiation. 19: 194-208. PMID 22048155 DOI: 10.1038/Cdd.2011.141  0.354
2012 Itkin T, Gur-Cohen S, Ludin A, Kalinkovich A, Golan K, Caglio G, Ornitz DM, Adams RH, Kollet O, Lapidot T. Endothelial Blood-Bone Marrow-Barrier Dynamically Regulates Balanced Stem and Progenitor Cell Trafficking and Maintenance Blood. 120: 507-507. DOI: 10.1182/Blood.V120.21.507.507  0.379
2011 Boulday G, Rudini N, Maddaluno L, Blécon A, Arnould M, Gaudric A, Chapon F, Adams RH, Dejana E, Tournier-Lasserve E. Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice. The Journal of Experimental Medicine. 208: 1835-47. PMID 21859843 DOI: 10.1084/jem.20110571  0.305
2010 Eilken HM, Adams RH. Dynamics of endothelial cell behavior in sprouting angiogenesis. Current Opinion in Cell Biology. 22: 617-25. PMID 20817428 DOI: 10.1016/j.ceb.2010.08.010  0.43
2010 Pitulescu ME, Schmidt I, Benedito R, Adams RH. Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice. Nature Protocols. 5: 1518-34. PMID 20725067 DOI: 10.1038/nprot.2010.113  0.372
2010 Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E. The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Developmental Cell. 18: 938-49. PMID 20627076 DOI: 10.1016/J.Devcel.2010.05.006  0.306
2010 Adams RH, Eichmann A. Axon guidance molecules in vascular patterning. Cold Spring Harbor Perspectives in Biology. 2: a001875. PMID 20452960 DOI: 10.1101/cshperspect.a001875  0.374
2010 Wang Y, Nakayama M, Pitulescu ME, Schmidt TS, Bochenek ML, Sakakibara A, Adams S, Davy A, Deutsch U, Lüthi U, Barberis A, Benjamin LE, Mäkinen T, Nobes CD, Adams RH. Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature. 465: 483-6. PMID 20445537 DOI: 10.1038/Nature09002  0.428
2010 Bochenek ML, Dickinson S, Astin JW, Adams RH, Nobes CD. Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding Journal of Cell Science. 123: 1235-1246. PMID 20233847 DOI: 10.1242/jcs.061903  0.36
2009 Kogata N, Tribe RM, Fässler R, Way M, Adams RH. Integrin-linked kinase controls vascular wall formation by negatively regulating Rho/ROCK-mediated vascular smooth muscle cell contraction. Genes & Development. 23: 2278-83. PMID 19797768 DOI: 10.1101/gad.535409  0.36
2009 Benedito R, Roca C, Sörensen I, Adams S, Gossler A, Fruttiger M, Adams RH. The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis Cell. 137: 1124-1135. PMID 19524514 DOI: 10.1016/j.cell.2009.03.025  0.307
2009 Rocha SF, Adams RH. Molecular differentiation and specialization of vascular beds. Angiogenesis. 12: 139-47. PMID 19212819 DOI: 10.1007/s10456-009-9132-x  0.395
2009 Sörensen I, Adams RH, Gossler A. DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries Blood. 113: 5680-5688. PMID 19144989 DOI: 10.1182/blood-2008-08-174508  0.378
2008 Kiefer F, Adams RH. Lymphatic endothelial differentiation: start out with Sox--carry on with Prox Genome Biology. 9: 243. PMID 19138383 DOI: 10.1186/gb-2008-9-12-243  0.348
2008 Bixel MG, Adams RH. Master and commander: Continued expression of Prox1 prevents the dedifferentiation of lymphatic endothelial cells Genes and Development. 22: 3232-3235. PMID 19056879 DOI: 10.1101/gad.1751908  0.373
2008 Foster K, Sheridan J, Veiga-Fernandes H, Roderick K, Pachnis V, Adams R, Blackburn C, Kioussis D, Coles M. Contribution of neural crest-derived cells in the embryonic and adult thymus. Journal of Immunology (Baltimore, Md. : 1950). 180: 3183-9. PMID 18292542 DOI: 10.4049/Jimmunol.180.5.3183  0.331
2008 Abraham S, Kogata N, Fässler R, Adams RH. Integrin β1 subunit controls mural cell adhesion, spreading, and blood vessel wall stability Circulation Research. 102: 562-570. PMID 18202311 DOI: 10.1161/CIRCRESAHA.107.167908  0.396
2007 Adams RH. Investigation of the angiogenic programme with tissue-specific and inducible genetic approaches in mice Novartis Foundation Symposium. 283: 165-171. PMID 18300421 DOI: 10.1002/9780470319413.CH13  0.346
2007 Roca C, Adams RH. Regulation of vascular morphogenesis by Notch signaling Genes and Development. 21: 2511-2524. PMID 17938237 DOI: 10.1101/gad.1589207  0.394
2007 Kuijper S, Turner CJ, Adams RH. Regulation of angiogenesis by Eph-ephrin interactions. Trends in Cardiovascular Medicine. 17: 145-51. PMID 17574121 DOI: 10.1016/j.tcm.2007.03.003  0.404
2007 Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis Nature Reviews Molecular Cell Biology. 8: 464-478. PMID 17522591 DOI: 10.1038/Nrm2183  0.383
2006 Kogata N, Arai Y, Pearson JT, Hashimoto K, Hidaka K, Koyama T, Somekawa S, Nakaoka Y, Ogawa M, Adams RH, Okada M, Mochizuki N. Cardiac ischemia activates vascular endothelial cadherin promoter in both preexisting vascular cells and bone marrow cells involved in neovascularization. Circulation Research. 98: 897-904. PMID 16543497 DOI: 10.1161/01.RES.0000218193.51136.ad  0.414
2006 Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N, Lindblom P, Shani M, Zicha D, Adams RH. Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 124: 161-73. PMID 16413489 DOI: 10.1016/j.cell.2005.10.034  0.382
2005 Mäkinen T, Adams RH, Bailey J, Lu Q, Ziemiecki A, Alitalo K, Klein R, Wilkinson GA. PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature Genes and Development. 19: 397-410. PMID 15687262 DOI: 10.1101/Gad.330105  0.324
2000 Adams RH, Klein R. Eph receptors and Ephrin ligands: Essential mediators of vascular development Trends in Cardiovascular Medicine. 10: 183-188. PMID 11282292 DOI: 10.1016/S1050-1738(00)00046-3  0.336
1999 Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U, Risau W, Klein R. Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis Genes and Development. 13: 295-306. PMID 9990854 DOI: 10.1101/GAD.13.3.295  0.406
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