Alexander Varshavsky - Publications

Affiliations: 
Biology and Biological Engineering California Institute of Technology, Pasadena, CA 
Area:
Protein degradation, ubiquitin
Website:
http://www.bbe.caltech.edu/content/alexander-j-varshavsky

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Year Citation  Score
2022 Kim BH, Kim MK, Oh SJ, Nguyen KT, Kim JH, Varshavsky A, Hwang CS, Song HK. Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates. Proceedings of the National Academy of Sciences of the United States of America. 119: e2209597119. PMID 35878037 DOI: 10.1073/pnas.2209597119  0.608
2021 Chen SJ, Kim L, Song HK, Varshavsky A. Aminopeptidases trim Xaa-Pro proteins, initiating their degradation by the Pro/N-degron pathway. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34663735 DOI: 10.1073/pnas.2115430118  0.644
2020 Vu TTM, Mitchell DC, Gygi SP, Varshavsky A. The Arg/N-degron pathway targets transcription factors and regulates specific genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 33229537 DOI: 10.1073/pnas.2020124117  0.39
2020 Vu TTM, Varshavsky A. The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway. Biochemistry. PMID 32692156 DOI: 10.1021/Acs.Biochem.0C00514  0.535
2020 Dong C, Chen SJ, Melnykov A, Weirich S, Sun K, Jeltsch A, Varshavsky A, Min J. Recognition of nonproline N-terminal residues by the Pro/N-degron pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 32513738 DOI: 10.1073/Pnas.2007085117  0.546
2020 Oh JH, Hyun JY, Chen SJ, Varshavsky A. Five enzymes of the Arg/N-degron pathway form a targeting complex: The concept of superchanneling. Proceedings of the National Academy of Sciences of the United States of America. PMID 32366662 DOI: 10.1073/Pnas.2003043117  0.483
2020 Chen SJ, Melnykov A, Varshavsky A. Evolution of Substrates and Components of the Pro/N-Degron Pathway. Biochemistry. PMID 31895557 DOI: 10.1021/Acs.Biochem.9B00953  0.564
2019 Melnykov A, Chen SJ, Varshavsky A. Gid10 as an alternative N-recognin of the Pro/N-degron pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 31337681 DOI: 10.1073/Pnas.1908304116  0.585
2019 Varshavsky A. On the cause of sleep: Protein fragments, the concept of sentinels, and links to epilepsy. Proceedings of the National Academy of Sciences of the United States of America. PMID 31085645 DOI: 10.1073/Pnas.1904709116  0.302
2019 Varshavsky A. N-degron and C-degron pathways of protein degradation. Proceedings of the National Academy of Sciences of the United States of America. 116: 358-366. PMID 30622213 DOI: 10.1073/Pnas.1816596116  0.514
2018 Kim JM, Seok OH, Ju S, Heo JE, Yeom J, Kim DS, Yoo JY, Varshavsky A, Lee C, Hwang CS. Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway. Science (New York, N.Y.). PMID 30409808 DOI: 10.1126/Science.Aat0174  0.591
2018 Dougan DA, Varshavsky A. Understanding the Pro/N-end rule pathway. Nature Chemical Biology. 14: 415-416. PMID 29662186 DOI: 10.1038/S41589-018-0045-0  0.573
2017 Oh JH, Chen SJ, Varshavsky A. A reference-based protein degradation assay without global translation inhibitors. The Journal of Biological Chemistry. PMID 29122887 DOI: 10.1074/Jbc.M117.814236  0.483
2017 Varshavsky A. The Ubiquitin System, Autophagy, and Regulated Protein Degradation. Annual Review of Biochemistry. 86: 123-128. PMID 28654326 DOI: 10.1146/Annurev-Biochem-061516-044859  0.426
2017 Oh JH, Hyun JY, Varshavsky A. Control of Hsp90 chaperone and its clients by N-terminal acetylation and the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 28515311 DOI: 10.1073/Pnas.1705898114  0.542
2017 Chen SJ, Wu X, Wadas B, Oh JH, Varshavsky A. An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes. Science (New York, N.Y.). 355. PMID 28126757 DOI: 10.1126/Science.Aal3655  0.812
2016 Wadas B, Piatkov K, Brower C, Varshavsky A. Analyzing N-terminal Arginylation Through the Use of Peptide Arrays and Degradation Assays. The Journal of Biological Chemistry. PMID 27510035 DOI: 10.1074/Jbc.M116.747956  0.827
2016 Wadas B, Borjigin J, Huang Z, Oh JH, Hwang CS, Varshavsky A. Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway. The Journal of Biological Chemistry. PMID 27339900 DOI: 10.1074/Jbc.M116.734640  0.824
2016 Liu YJ, Liu C, Chang Z, Wadas B, Brower CS, Song ZH, Xu ZL, Shang YL, Liu WX, Wang LN, Dong W, Varshavsky A, Hu RG, Li W. Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway. The Journal of Biological Chemistry. PMID 26858254 DOI: 10.1074/Jbc.M116.714964  0.832
2015 Piatkov KI, Vu TT, Hwang CS, Varshavsky A. Formyl-methionine as a degradation signal at the N-termini of bacterial proteins. Microbial Cell. 2: 376-393. PMID 26866044 DOI: 10.15698/Mic2015.10.231  0.595
2015 Park SE, Kim JM, Seok OH, Cho H, Wadas B, Kim SY, Varshavsky A, Hwang CS. Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway. Science (New York, N.Y.). 347: 1249-52. PMID 25766235 DOI: 10.1126/Science.Aaa3844  0.836
2014 Brower CS, Rosen CE, Jones RH, Wadas BC, Piatkov KI, Varshavsky A. Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats. Proceedings of the National Academy of Sciences of the United States of America. 111: E4936-45. PMID 25369936 DOI: 10.1073/Pnas.1419587111  0.83
2014 Piatkov KI, Oh JH, Liu Y, Varshavsky A. Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 111: E817-26. PMID 24550490 DOI: 10.1073/Pnas.1401639111  0.56
2014 Kim HK, Kim RR, Oh JH, Cho H, Varshavsky A, Hwang CS. The N-terminal methionine of cellular proteins as a degradation signal. Cell. 156: 158-69. PMID 24361105 DOI: 10.1016/J.Cell.2013.11.031  0.594
2013 Piatkov K, Graciet E, Varshavsky A. Ubiquitin reference technique and its use in ubiquitin-lacking prokaryotes. Plos One. 8: e67952. PMID 23825692 DOI: 10.1371/Journal.Pone.0067952  0.477
2013 Shemorry A, Hwang CS, Varshavsky A. Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway. Molecular Cell. 50: 540-51. PMID 23603116 DOI: 10.1016/J.Molcel.2013.03.018  0.831
2013 Brower CS, Piatkov KI, Varshavsky A. Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway. Molecular Cell. 50: 161-71. PMID 23499006 DOI: 10.1016/J.Molcel.2013.02.009  0.512
2012 Piatkov KI, Colnaghi L, Békés M, Varshavsky A, Huang TT. The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway. Molecular Cell. 48: 926-33. PMID 23159736 DOI: 10.1016/J.Molcel.2012.10.012  0.503
2012 Piatkov KI, Brower CS, Varshavsky A. The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments. Proceedings of the National Academy of Sciences of the United States of America. 109: E1839-47. PMID 22670058 DOI: 10.1073/Pnas.1207786109  0.485
2012 Varshavsky A. The ubiquitin system, an immense realm. Annual Review of Biochemistry. 81: 167-76. PMID 22663079 DOI: 10.1146/Annurev-Biochem-051910-094049  0.487
2012 Varshavsky A. Three decades of studies to understand the functions of the ubiquitin family. Methods in Molecular Biology (Clifton, N.J.). 832: 1-11. PMID 22350874 DOI: 10.1007/978-1-61779-474-2_1  0.498
2011 Hwang CS, Sukalo M, Batygin O, Addor MC, Brunner H, Aytes AP, Mayerle J, Song HK, Varshavsky A, Zenker M. Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome. Plos One. 6: e24925. PMID 21931868 DOI: 10.1371/Journal.Pone.0024925  0.594
2011 Varshavsky A. The N-end rule pathway and regulation by proteolysis. Protein Science : a Publication of the Protein Society. 20: 1298-345. PMID 21633985 DOI: 10.1002/Pro.666  0.597
2010 Hwang CS, Shemorry A, Auerbach D, Varshavsky A. The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases. Nature Cell Biology. 12: 1177-85. PMID 21076411 DOI: 10.1038/Ncb2121  0.82
2010 Brower CS, Veiga L, Jones RH, Varshavsky A. Mouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcription. The Journal of Biological Chemistry. 285: 17218-34. PMID 20356838 DOI: 10.1074/Jbc.M110.118638  0.42
2010 Hwang CS, Shemorry A, Varshavsky A. N-terminal acetylation of cellular proteins creates specific degradation signals. Science (New York, N.Y.). 327: 973-7. PMID 20110468 DOI: 10.1126/Science.1183147  0.845
2009 Brower CS, Varshavsky A. Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations. Plos One. 4: e7757. PMID 19915679 DOI: 10.1371/Journal.Pone.0007757  0.475
2009 Graciet E, Walter F, Ó'Maoiléidigh DS, Pollmann S, Meyerowitz EM, Varshavsky A, Wellmer F. The N-end rule pathway controls multiple functions during Arabidopsis shoot and leaf development. Proceedings of the National Academy of Sciences of the United States of America. 106: 13618-23. PMID 19620738 DOI: 10.1073/Pnas.0906404106  0.533
2009 Wang H, Piatkov KI, Brower CS, Varshavsky A. Glutamine-specific N-terminal amidase, a component of the N-end rule pathway. Molecular Cell. 34: 686-95. PMID 19560421 DOI: 10.1016/J.Molcel.2009.04.032  0.488
2009 Hwang CS, Shemorry A, Varshavsky A. Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase. Proceedings of the National Academy of Sciences of the United States of America. 106: 2142-7. PMID 19164530 DOI: 10.1073/Pnas.0812316106  0.814
2008 Varshavsky A. The N-end rule at atomic resolution. Nature Structural & Molecular Biology. 15: 1238-40. PMID 19050717 DOI: 10.1038/Nsmb1208-1238  0.349
2008 Hwang CS, Varshavsky A. Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 105: 19188-93. PMID 19033468 DOI: 10.1073/Pnas.0808891105  0.422
2008 Xia Z, Turner GC, Hwang CS, Byrd C, Varshavsky A. Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter. The Journal of Biological Chemistry. 283: 28958-68. PMID 18708352 DOI: 10.1074/Jbc.M803980200  0.419
2008 Xia Z, Webster A, Du F, Piatkov K, Ghislain M, Varshavsky A. Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway. The Journal of Biological Chemistry. 283: 24011-28. PMID 18566452 DOI: 10.1074/Jbc.M802583200  0.462
2008 Connor RE, Piatkov K, Varshavsky A, Tirrell DA. Enzymatic N-terminal addition of noncanonical amino acids to peptides and proteins. Chembiochem : a European Journal of Chemical Biology. 9: 366-9. PMID 18203209 DOI: 10.1002/Cbic.200700605  0.458
2008 Hu RG, Wang H, Xia Z, Varshavsky A. The N-end rule pathway is a sensor of heme. Proceedings of the National Academy of Sciences of the United States of America. 105: 76-81. PMID 18162538 DOI: 10.1073/Pnas.0710568105  0.511
2007 Varshavsky A. Targeting the absence: homozygous DNA deletions as immutable signposts for cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. 104: 14935-40. PMID 17846424 DOI: 10.1073/Pnas.0706546104  0.314
2007 Schnupf P, Zhou J, Varshavsky A, Portnoy DA. Listeriolysin O secreted by Listeria monocytogenes into the host cell cytosol is degraded by the N-end rule pathway. Infection and Immunity. 75: 5135-47. PMID 17682039 DOI: 10.1128/Iai.00164-07  0.458
2007 Tasaki T, Sohr R, Xia Z, Hellweg R, Hörtnagl H, Varshavsky A, Kwon YT. Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems. The Journal of Biological Chemistry. 282: 18510-20. PMID 17462990 DOI: 10.1074/Jbc.M701894200  0.469
2006 Hu RG, Brower CS, Wang H, Davydov IV, Sheng J, Zhou J, Kwon YT, Varshavsky A. Arginyltransferase, its specificity, putative substrates, bidirectional promoter, and splicing-derived isoforms. The Journal of Biological Chemistry. 281: 32559-73. PMID 16943202 DOI: 10.1074/Jbc.M604355200  0.592
2006 An JY, Seo JW, Tasaki T, Lee MJ, Varshavsky A, Kwon YT. Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 103: 6212-7. PMID 16606826 DOI: 10.1073/Pnas.0601700103  0.526
2006 Varshavsky A. The early history of the ubiquitin field. Protein Science : a Publication of the Protein Society. 15: 647-54. PMID 16501229 DOI: 10.1110/Ps.052012306  0.464
2006 Graciet E, Hu RG, Piatkov K, Rhee JH, Schwarz EM, Varshavsky A. Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen. Proceedings of the National Academy of Sciences of the United States of America. 103: 3078-83. PMID 16492767 DOI: 10.1073/Pnas.0511224103  0.422
2006 Varshavsky A. The origins of the ubiquitin field Israel Journal of Chemistry. 46: 137-144. DOI: 10.1560/5E71-3Uu5-1Nh2-6Uyj  0.465
2006 Zenker M, Mayerle J, Lerch MM, Tagariello A, Zerres K, Durie PR, Beier M, Hülskamp G, Guzman C, Rehder H, Beemer FA, Hamel B, Vanlieferinghen P, Gershoni-Baruch R, Vieira MW, ... ... Varshavsky A, et al. Erratum: Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome) (Nature Genetics (2005) 37 (1345-1350)) Nature Genetics. 38. DOI: 10.1038/Ng0206-265  0.356
2005 Dohmen RJ, Varshavsky A. Heat-inducible degron and the making of conditional mutants. Methods in Enzymology. 399: 799-822. PMID 16338396 DOI: 10.1016/S0076-6879(05)99052-6  0.387
2005 Varshavsky A. Ubiquitin fusion technique and related methods. Methods in Enzymology. 399: 777-99. PMID 16338395 DOI: 10.1016/S0076-6879(05)99051-4  0.379
2005 Zenker M, Mayerle J, Lerch MM, Tagariello A, Zerres K, Durie PR, Beier M, Hülskamp G, Guzman C, Rehder H, Beemer FA, Hamel B, Vanlieferinghen P, Gershoni-Baruch R, Vieira MW, ... ... Varshavsky A, et al. Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). Nature Genetics. 37: 1345-50. PMID 16311597 DOI: 10.1038/Ng1681  0.415
2005 Hu RG, Sheng J, Qi X, Xu Z, Takahashi TT, Varshavsky A. The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature. 437: 981-6. PMID 16222293 DOI: 10.1038/Nature04027  0.513
2005 Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT. A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons. Molecular and Cellular Biology. 25: 7120-36. PMID 16055722 DOI: 10.1128/Mcb.25.16.7120-7136.2005  0.572
2004 Yin J, Kwon YT, Varshavsky A, Wang W. RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Human Molecular Genetics. 13: 2421-30. PMID 15317757 DOI: 10.1093/Hmg/Ddh269  0.491
2004 Finley D, Ciechanover A, Varshavsky A. Ubiquitin as a central cellular regulator. Cell. 116: S29-32, 2 p followin. PMID 15055578 DOI: 10.1016/S0092-8674(03)00971-1  0.549
2003 Kwon YT, Xia Z, An JY, Tasaki T, Davydov IV, Seo JW, Sheng J, Xie Y, Varshavsky A. Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. Molecular and Cellular Biology. 23: 8255-71. PMID 14585983 DOI: 10.1128/Mcb.23.22.8255-8271.2003  0.473
2003 Varshavsky A. The N-end rule and regulation of apoptosis. Nature Cell Biology. 5: 373-6. PMID 12724766 DOI: 10.1038/Ncb0503-373  0.534
2002 Xie Y, Varshavsky A. UFD4 lacking the proteasome-binding region catalyses ubiquitination but is impaired in proteolysis. Nature Cell Biology. 4: 1003-7. PMID 12447385 DOI: 10.1038/Ncb889  0.425
2002 Sheng J, Kumagai A, Dunphy WG, Varshavsky A. Dissection of c-MOS degron. The Embo Journal. 21: 6061-71. PMID 12426378 DOI: 10.1093/Emboj/Cdf626  0.398
2002 Du F, Navarro-Garcia F, Xia Z, Tasaki T, Varshavsky A. Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain. Proceedings of the National Academy of Sciences of the United States of America. 99: 14110-5. PMID 12391316 DOI: 10.1073/Pnas.172527399  0.532
2002 Kwon YT, Kashina AS, Davydov IV, Hu RG, An JY, Seo JW, Du F, Varshavsky A. An essential role of N-terminal arginylation in cardiovascular development. Science (New York, N.Y.). 297: 96-9. PMID 12098698 DOI: 10.1126/Science.1069531  0.55
2001 Kwon YT, Xia Z, Davydov IV, Lecker SH, Varshavsky A. Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway. Molecular and Cellular Biology. 21: 8007-21. PMID 11689692 DOI: 10.1128/Mcb.21.23.8007-8021.2001  0.558
2001 Rao H, Uhlmann F, Nasmyth K, Varshavsky A. Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature. 410: 955-9. PMID 11309624 DOI: 10.1038/35073627  0.557
2001 Xie Y, Varshavsky A. RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit. Proceedings of the National Academy of Sciences of the United States of America. 98: 3056-61. PMID 11248031 DOI: 10.1073/Pnas.071022298  0.452
2000 Varshavsky A. Recent studies of the ubiquitin system and the N-end rule pathway. Harvey Lectures. 96: 93-116. PMID 12200873  0.401
2000 Varshavsky A, Turner G, Du F, Xie Y. Felix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway. Biological Chemistry. 381: 779-89. PMID 11076011 DOI: 10.1515/Bc.2000.101  0.535
2000 Varshavsky A. Ubiquitin fusion technique and its descendants. Methods in Enzymology. 327: 578-93. PMID 11045010 DOI: 10.1016/S0076-6879(00)27303-5  0.397
2000 Turner GC, Varshavsky A. Detecting and measuring cotranslational protein degradation in vivo. Science (New York, N.Y.). 289: 2117-20. PMID 11000112 DOI: 10.1126/Science.289.5487.2117  0.473
2000 Turner GC, Du F, Varshavsky A. Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature. 405: 579-83. PMID 10850718 DOI: 10.1038/35014629  0.496
2000 Kwon YT, Balogh SA, Davydov IV, Kashina AS, Yoon JK, Xie Y, Gaur A, Hyde L, Denenberg VH, Varshavsky A. Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway. Molecular and Cellular Biology. 20: 4135-48. PMID 10805755 DOI: 10.1128/Mcb.20.11.4135-4148.2000  0.528
2000 Davydov IV, Varshavsky A. RGS4 is arginylated and degraded by the N-end rule pathway in vitro. The Journal of Biological Chemistry. 275: 22931-41. PMID 10783390 DOI: 10.1074/Jbc.M001605200  0.582
2000 Xie Y, Varshavsky A. Physical association of ubiquitin ligases and the 26S proteasome. Proceedings of the National Academy of Sciences of the United States of America. 97: 2497-502. PMID 10688918 DOI: 10.1073/Pnas.060025497  0.425
1999 Xie Y, Varshavsky A. The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain. The Embo Journal. 18: 6832-44. PMID 10581257 DOI: 10.1093/Emboj/18.23.6832  0.447
1999 Suzuki T, Varshavsky A. Degradation signals in the lysine-asparagine sequence space. The Embo Journal. 18: 6017-26. PMID 10545113 DOI: 10.1093/Emboj/18.21.6017  0.524
1999 Xie Y, Varshavsky A. The N-end rule pathway is required for import of histidine in yeast lacking the kinesin-like protein Cin8p. Current Genetics. 36: 113-23. PMID 10501933 DOI: 10.1007/S002940050480  0.529
1999 Kwon YT, Lévy F, Varshavsky A. Bivalent inhibitor of the N-end rule pathway. The Journal of Biological Chemistry. 274: 18135-9. PMID 10364269 DOI: 10.1074/Jbc.274.25.18135  0.511
1999 Dünnwald M, Varshavsky A, Johnsson N. Detection of transient in vivo interactions between substrate and transporter during protein translocation into the endoplasmic reticulum. Molecular Biology of the Cell. 10: 329-44. PMID 9950680 DOI: 10.1091/Mbc.10.2.329  0.426
1999 Lévy F, Johnston JA, Varshavsky A. Analysis of a conditional degradation signal in yeast and mammalian cells. European Journal of Biochemistry / Febs. 259: 244-52. PMID 9914499 DOI: 10.1046/J.1432-1327.1999.00024.X  0.565
1999 Kwon YT, Kashina AS, Varshavsky A. Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway. Molecular and Cellular Biology. 19: 182-93. PMID 9858543 DOI: 10.1128/Mcb.19.1.182  0.507
1998 Davydov IV, Patra D, Varshavsky A. The N-end rule pathway in Xenopus egg extracts. Archives of Biochemistry and Biophysics. 357: 317-25. PMID 9735173 DOI: 10.1006/Abbi.1998.0829  0.508
1998 Finley D, Tanaka K, Mann C, Feldmann H, Hochstrasser M, Vierstra R, Johnston S, Hampton R, Haber J, Mccusker J, Silver P, Frontali L, Thorsness P, Varshavsky A, Byers B, et al. Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends in Biochemical Sciences. 23: 244-5. PMID 9697412 DOI: 10.1016/S0968-0004(98)01222-5  0.712
1998 Kwon YT, Reiss Y, Fried VA, Hershko A, Yoon JK, Gonda DK, Sangan P, Copeland NG, Jenkins NA, Varshavsky A. The mouse and human genes encoding the recognition component of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 95: 7898-903. PMID 9653112 DOI: 10.1073/Pnas.95.14.7898  0.541
1998 Ramos PC, Höckendorff J, Johnson ES, Varshavsky A, Dohmen RJ. Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell. 92: 489-99. PMID 9491890 DOI: 10.1016/S0092-8674(00)80942-3  0.344
1998 Byrd C, Turner GC, Varshavsky A. The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor. The Embo Journal. 17: 269-77. PMID 9427760 DOI: 10.1093/Emboj/17.1.269  0.546
1997 Varshavsky A. The ubiquitin system. Trends in Biochemical Sciences. 22: 383-7. PMID 9357313 DOI: 10.1016/S0968-0004(97)01122-5  0.465
1997 Varshavsky A. The N-end rule pathway of protein degradation. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 2: 13-28. PMID 9112437 DOI: 10.1046/J.1365-2443.1997.1020301.X  0.576
1997 Varshavsky A, Byrd C, Kwon YT. Recent studies of the n-end rule pathway Faseb Journal. 11: A995.  0.363
1996 Grigoryev S, Stewart AE, Kwon YT, Arfin SM, Bradshaw RA, Jenkins NA, Copeland NG, Varshavsky A. A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway. The Journal of Biological Chemistry. 271: 28521-32. PMID 8910481 DOI: 10.1074/Jbc.271.45.28521  0.539
1996 Varshavsky A. The N-end rule: functions, mysteries, uses. Proceedings of the National Academy of Sciences of the United States of America. 93: 12142-9. PMID 8901547 DOI: 10.1073/Pnas.93.22.12142  0.524
1996 Ghislain M, Dohmen RJ, Levy F, Varshavsky A. Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae. The Embo Journal. 15: 4884-99. PMID 8890162 DOI: 10.1002/J.1460-2075.1996.Tb00869.X  0.553
1996 Lévy F, Johnsson N, Rümenapf T, Varshavsky A. Using ubiquitin to follow the metabolic fate of a protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 4907-12. PMID 8643502 DOI: 10.1073/Pnas.93.10.4907  0.488
1995 Varshavsky A. The N-end rule. Cold Spring Harbor Symposia On Quantitative Biology. 60: 461-78. PMID 8824420 DOI: 10.1101/Sqb.1995.060.01.051  0.443
1995 Baker RT, Varshavsky A. Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway. The Journal of Biological Chemistry. 270: 12065-74. PMID 7744855 DOI: 10.1074/Jbc.270.20.12065  0.561
1995 Varshavsky A. Codominance and toxins: a path to drugs of nearly unlimited selectivity. Proceedings of the National Academy of Sciences of the United States of America. 92: 3663-7. PMID 7731961 DOI: 10.1073/Pnas.92.9.3663  0.327
1995 Johnston JA, Johnson ES, Waller PR, Varshavsky A. Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway. The Journal of Biological Chemistry. 270: 8172-8. PMID 7713922 DOI: 10.1074/Jbc.270.14.8172  0.58
1995 Dohmen RJ, Stappen R, McGrath JP, Forrová H, Kolarov J, Goffeau A, Varshavsky A. An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. The Journal of Biological Chemistry. 270: 18099-109. PMID 7629121 DOI: 10.1074/Jbc.270.30.18099  0.426
1995 Johnson ES, Ma PC, Ota IM, Varshavsky A. A proteolytic pathway that recognizes ubiquitin as a degradation signal. The Journal of Biological Chemistry. 270: 17442-56. PMID 7615550 DOI: 10.1074/Jbc.270.29.17442  0.562
1994 Dohmen RJ, Wu P, Varshavsky A. Heat-inducible degron: a method for constructing temperature-sensitive mutants. Science (New York, N.Y.). 263: 1273-6. PMID 8122109 DOI: 10.1126/Science.8122109  0.452
1994 Madura K, Varshavsky A. Degradation of G alpha by the N-end rule pathway. Science (New York, N.Y.). 265: 1454-8. PMID 8073290 DOI: 10.1126/Science.8073290  0.487
1994 Johnsson N, Varshavsky A. Ubiquitin-assisted dissection of protein transport across membranes. The Embo Journal. 13: 2686-98. PMID 8013467 DOI: 10.1002/J.1460-2075.1994.Tb06559.X  0.42
1994 Johnsson N, Varshavsky A. Split ubiquitin as a sensor of protein interactions in vivo. Proceedings of the National Academy of Sciences of the United States of America. 91: 10340-4. PMID 7937952 DOI: 10.1073/Pnas.91.22.10340  0.469
1993 Madura K, Dohmen RJ, Varshavsky A. N-recognin/Ubc2 interactions in the N-end rule pathway. The Journal of Biological Chemistry. 268: 12046-54. PMID 8505328  0.454
1993 Shrader TE, Tobias JW, Varshavsky A. The N-end rule in Escherichia coli: cloning and analysis of the leucyl, phenylalanyl-tRNA-protein transferase gene aat. Journal of Bacteriology. 175: 4364-74. PMID 8331068 DOI: 10.1128/Jb.175.14.4364-4374.1993  0.535
1993 Ota IM, Varshavsky A. A yeast protein similar to bacterial two-component regulators. Science (New York, N.Y.). 262: 566-9. PMID 8211183 DOI: 10.1126/Science.8211183  0.431
1992 Ota IM, Varshavsky A. A gene encoding a putative tyrosine phosphatase suppresses lethality of an N-end rule-dependent mutant. Proceedings of the National Academy of Sciences of the United States of America. 89: 2355-9. PMID 1549598 DOI: 10.1073/Pnas.89.6.2355  0.564
1992 Baker RT, Tobias JW, Varshavsky A. Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family. The Journal of Biological Chemistry. 267: 23364-75. PMID 1429680  0.34
1992 Varshavsky A. The N-end rule. Cell. 69: 725-35. PMID 1317266 DOI: 10.1016/0092-8674(92)90285-K  0.443
1992 Johnson ES, Bartel B, Seufert W, Varshavsky A. Ubiquitin as a degradation signal. The Embo Journal. 11: 497-505. PMID 1311250 DOI: 10.1002/J.1460-2075.1992.Tb05080.X  0.692
1991 Tobias JW, Varshavsky A. Cloning and functional analysis of the ubiquitin-specific protease gene UBP1 of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 266: 12021-8. PMID 2050695  0.366
1991 McGrath JP, Jentsch S, Varshavsky A. UBA 1: an essential yeast gene encoding ubiquitin-activating enzyme. The Embo Journal. 10: 227-36. PMID 1989885 DOI: 10.1002/J.1460-2075.1991.Tb07940.X  0.673
1991 Varshavsky A. Naming a targeting signal. Cell. 64: 13-5. PMID 1986863 DOI: 10.1016/0092-8674(91)90202-A  0.368
1991 Tobias JW, Shrader TE, Rocap G, Varshavsky A. The N-end rule in bacteria. Science (New York, N.Y.). 254: 1374-7. PMID 1962196 DOI: 10.1126/Science.1962196  0.559
1991 Baker RT, Varshavsky A. Inhibition of the N-end rule pathway in living cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 1090-4. PMID 1899923  0.476
1991 Dohmen RJ, Madura K, Bartel B, Varshavsky A. The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme. Proceedings of the National Academy of Sciences of the United States of America. 88: 7351-5. PMID 1651502 DOI: 10.1073/Pnas.88.16.7351  0.754
1991 Hochstrasser M, Ellison MJ, Chau V, Varshavsky A. The short-lived MAT alpha 2 transcriptional regulator is ubiquitinated in vivo. Proceedings of the National Academy of Sciences of the United States of America. 88: 4606-10. PMID 1647011 DOI: 10.1073/Pnas.88.11.4606  0.709
1990 Bartel B, Wünning I, Varshavsky A. The recognition component of the N-end rule pathway. The Embo Journal. 9: 3179-89. PMID 2209542 DOI: 10.1002/J.1460-2075.1990.Tb07516.X  0.769
1990 Balzi E, Choder M, Chen WN, Varshavsky A, Goffeau A. Cloning and functional analysis of the arginyl-tRNA-protein transferase gene ATE1 of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 265: 7464-71. PMID 2185248  0.438
1990 Johnson ES, Gonda DK, Varshavsky A. cis-trans recognition and subunit-specific degradation of short-lived proteins. Nature. 346: 287-91. PMID 2165217 DOI: 10.1038/346287A0  0.57
1990 Hochstrasser M, Varshavsky A. In vivo degradation of a transcriptional regulator: the yeast alpha 2 repressor. Cell. 61: 697-708. PMID 2111732 DOI: 10.1016/0092-8674(90)90481-S  0.428
1989 Winter E, Varshavsky A. A DNA binding protein that recognizes oligo(dA).oligo(dT) tracts. The Embo Journal. 8: 1867-77. PMID 2670564 DOI: 10.1002/J.1460-2075.1989.Tb03583.X  0.425
1989 McGrath JP, Varshavsky A. The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature. 340: 400-4. PMID 2569166 DOI: 10.1038/340400A0  0.352
1989 Varshavsky A, Bachmair A, Finley D, Gonda DK, Wünning I. Targeting of proteins for degradation. Biotechnology (Reading, Mass.). 13: 109-43. PMID 2553172  0.54
1989 Chau V, Tobias JW, Bachmair A, Marriott D, Ecker DJ, Gonda DK, Varshavsky A. A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science (New York, N.Y.). 243: 1576-83. PMID 2538923 DOI: 10.1126/Science.2538923  0.372
1989 Finley D, Bartel B, Varshavsky A. The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis. Nature. 338: 394-401. PMID 2538753 DOI: 10.1038/338394A0  0.745
1989 Bachmair A, Varshavsky A. The degradation signal in a short-lived protein. Cell. 56: 1019-32. PMID 2538246 DOI: 10.1016/0092-8674(89)90635-1  0.475
1989 Gonda DK, Bachmair A, Wünning I, Tobias JW, Lane WS, Varshavsky A. Universality and structure of the N-end rule. The Journal of Biological Chemistry. 264: 16700-12. PMID 2506181  0.397
1988 Goebl MG, Yochem J, Jentsch S, McGrath JP, Varshavsky A, Byers B. The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme. Science (New York, N.Y.). 241: 1331-5. PMID 2842867 DOI: 10.1126/Science.2842867  0.64
1988 Bartel B, Varshavsky A. Hypersensitivity to heavy water: a new conditional phenotype. Cell. 52: 935-41. PMID 2832067 DOI: 10.1016/0092-8674(88)90435-7  0.587
1988 Solomon MJ, Larsen PL, Varshavsky A. Mapping protein-DNA interactions in vivo with formaldehyde: evidence that histone H4 is retained on a highly transcribed gene. Cell. 53: 937-47. PMID 2454748 DOI: 10.1016/S0092-8674(88)90469-2  0.579
1987 Varshavsky A, Bachmair A, Finley D. The N-end rule of selective protein turnover: mechanistic aspects and functional implications. Biochemical Society Transactions. 15: 815-6. PMID 3691950 DOI: 10.1042/Bst0150815  0.652
1987 Varshavsky A. Electrophoretic assay for DNA-binding proteins. Methods in Enzymology. 151: 551-65. PMID 3431454 DOI: 10.1016/S0076-6879(87)51044-8  0.337
1987 Jentsch S, McGrath JP, Varshavsky A. The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature. 329: 131-4. PMID 3306404 DOI: 10.1038/329131A0  0.641
1987 Ozkaynak E, Finley D, Solomon MJ, Varshavsky A. The yeast ubiquitin genes: a family of natural gene fusions. The Embo Journal. 6: 1429-39. PMID 3038523 DOI: 10.1002/J.1460-2075.1987.Tb02384.X  0.711
1987 Finley D, Ozkaynak E, Varshavsky A. The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses. Cell. 48: 1035-46. PMID 3030556 DOI: 10.1016/0092-8674(87)90711-2  0.597
1987 Solomon MJ, Varshavsky A. A nuclease-hypersensitive region forms de novo after chromosome replication. Molecular and Cellular Biology. 7: 3822-5. PMID 2824998 DOI: 10.1128/Mcb.7.10.3822  0.494
1987 Varshavsky A, Bachmair A, Finley D. The N-End Rule of Selective Protein Turnover and Its Implications [Abstract Only] Philosophical Transactions of the Royal Society B. 317: 471-471. DOI: 10.1098/Rstb.1987.0073  0.707
1986 Solomon MJ, Strauss F, Varshavsky A. A mammalian high mobility group protein recognizes any stretch of six A.T base pairs in duplex DNA. Proceedings of the National Academy of Sciences of the United States of America. 83: 1276-80. PMID 3456586 DOI: 10.1073/Pnas.83.5.1276  0.568
1986 Bachmair A, Finley D, Varshavsky A. In vivo half-life of a protein is a function of its amino-terminal residue. Science (New York, N.Y.). 234: 179-86. PMID 3018930 DOI: 10.1126/Science.3018930  0.609
1986 Swerdlow PS, Finley D, Varshavsky A. Enhancement of immunoblot sensitivity by heating of hydrated filters. Analytical Biochemistry. 156: 147-53. PMID 3017146 DOI: 10.1016/0003-2697(86)90166-1  0.481
1985 Ciccarelli RB, Solomon MJ, Varshavsky A, Lippard SJ. In vivo effects of cis- and trans-diamminedichloroplatinum(II) on SV40 chromosomes: differential repair, DNA-protein cross-linking, and inhibition of replication. Biochemistry. 24: 7533-40. PMID 3004558 DOI: 10.1021/Bi00347A005  0.53
1985 Solomon MJ, Varshavsky A. Formaldehyde-mediated DNA-protein crosslinking: a probe for in vivo chromatin structures. Proceedings of the National Academy of Sciences of the United States of America. 82: 6470-4. PMID 2995966 DOI: 10.1073/Pnas.82.19.6470  0.566
1985 Ciechanover A, Finley D, Varshavsky A. Mammalian cell cycle mutant defective in intracellular protein degradation and ubiquitin-protein conjugation. Progress in Clinical and Biological Research. 180: 17-31. PMID 2994083  0.606
1985 Finley D, Varshavsky A. The ubiquitin system: functions and mechanisms Trends in Biochemical Sciences. 10: 343-347. DOI: 10.1016/0968-0004(85)90108-2  0.623
1984 Strauss F, Varshavsky A. A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome. Cell. 37: 889-901. PMID 6540146 DOI: 10.1016/0092-8674(84)90424-0  0.356
1984 Ciechanover A, Finley D, Varshavsky A. The ubiquitin-mediated proteolytic pathway and mechanisms of energy-dependent intracellular protein degradation. Journal of Cellular Biochemistry. 24: 27-53. PMID 6327743 DOI: 10.1002/Jcb.240240104  0.593
1984 Ciechanover A, Finley D, Varshavsky A. Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85. Cell. 37: 57-66. PMID 6327060 DOI: 10.1016/0092-8674(84)90300-3  0.611
1984 Finley D, Ciechanover A, Varshavsky A. Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85. Cell. 37: 43-55. PMID 6327059 DOI: 10.1016/0092-8674(84)90299-X  0.626
1984 Ozkaynak E, Finley D, Varshavsky A. The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein. Nature. 312: 663-6. PMID 6095120 DOI: 10.1038/312663A0  0.648
1983 Varshavsky A. Do stalled replication forks synthesize a specific alarmone? Journal of Theoretical Biology. 105: 707-14. PMID 6672476 DOI: 10.1016/0022-5193(83)90228-X  0.323
1983 Varshavsky A, Levinger L, Sundin O, Barsoum J, Ozkaynak E, Swerdlow P, Finley D. Cellular and SV40 chromatin: replication, segregation, ubiquitination, nuclease-hypersensitive sites, HMG-containing nucleosomes, and heterochromatin-specific protein. Cold Spring Harbor Symposia On Quantitative Biology. 47: 511-28. PMID 6305564 DOI: 10.1101/Sqb.1983.047.01.061  0.593
1983 Swerdlow PS, Varshavsky A. Affinity of HMG17 for a mononucleosome is not influenced by the presence of ubiquitin-H2A semihistone but strongly depends on DNA fragment size. Nucleic Acids Research. 11: 387-401. PMID 6298725 DOI: 10.1093/Nar/11.2.387  0.34
1982 Levinger L, Varshavsky A. Protein D1 preferentially binds A + T-rich DNA in vitro and is a component of Drosophila melanogaster nucleosomes containing A + T-rich satellite DNA. Proceedings of the National Academy of Sciences of the United States of America. 79: 7152-6. PMID 6818540 DOI: 10.1073/Pnas.79.23.7152  0.314
1982 Levinger L, Varshavsky A. Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the Drosophila genome. Cell. 28: 375-85. PMID 6277512 DOI: 10.1016/0092-8674(82)90355-5  0.355
1981 Levinger L, Barsoum J, Varshavsky A. Two-dimensional hybridization mapping of nucleosomes. comparison of DNA and protein patterns. Journal of Molecular Biology. 146: 287-304. PMID 7265232 DOI: 10.1016/0022-2836(81)90389-2  0.325
1980 Levinger L, Varshavsky A. High-resolution fractionation of nucleosomes: minor particles, "whiskers," and separation of mononucleosomes containing and lacking A24 semihistone. Proceedings of the National Academy of Sciences of the United States of America. 77: 3244-8. PMID 6932019 DOI: 10.1073/Pnas.77.6.3244  0.315
Low-probability matches (unlikely to be authored by this person)
1981 Varshavsky A. On the possibility of metabolic control of replicon "misfiring": relationship to emergence of malignant phenotypes in mammalian cell lineages. Proceedings of the National Academy of Sciences of the United States of America. 78: 3673-7. PMID 6943571 DOI: 10.1073/Pnas.78.6.3673  0.298
2008 Varshavsky A. Discovery of cellular regulation by protein degradation. The Journal of Biological Chemistry. 283: 34469-89. PMID 18708349 DOI: 10.1074/Jbc.X800009200  0.293
1981 Sundin O, Varshavsky A. Arrest of segregation leads to accumulation of highly intertwined catenated dimers: dissection of the final stages of SV40 DNA replication. Cell. 25: 659-69. PMID 6269752 DOI: 10.1016/0092-8674(81)90173-2  0.293
1980 Sundin O, Varshavsky A. Terminal stages of SV40 DNA replication proceed via multiply intertwined catenated dimers. Cell. 21: 103-14. PMID 6250706 DOI: 10.1016/0092-8674(80)90118-X  0.291
1983 Snapka RM, Varshavsky A. Loss of unstably amplified dihydrofolate reductase genes from mouse cells is greatly accelerated by hydroxyurea. Proceedings of the National Academy of Sciences of the United States of America. 80: 7533-7. PMID 6584871 DOI: 10.1073/Pnas.80.24.7533  0.284
1977 Varshavsky AJ, Nedospasov SA, Bakayev VV, Bakayeva TG, Georgiev GP. Histone-like proteins in the purified Escherichia coli deoxyribonucleoprotein. Nucleic Acids Research. 4: 2725-45. PMID 333393  0.283
1986 Gros P, Croop J, Roninson I, Varshavsky A, Housman DE. Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 337-41. PMID 3455770 DOI: 10.1073/Pnas.83.2.337  0.282
1986 Snapka RM, Kwok K, Bernard JA, Harling OK, Varshavsky A. Post-separation detection of nucleic acids and proteins by neutron activation. Proceedings of the National Academy of Sciences of the United States of America. 83: 8939-42. PMID 3466168 DOI: 10.1073/Pnas.83.23.8939  0.272
1979 Sundin O, Varshavsky A. Staphylococcal nuclease makes a single non-random cut in the simian virus 40 viral minichromosome. Journal of Molecular Biology. 132: 535-46. PMID 230353 DOI: 10.1016/0022-2836(79)90274-2  0.268
2005 Varshavsky A. Regulated protein degradation. Trends in Biochemical Sciences. 30: 283-6. PMID 15950869 DOI: 10.1016/J.Tibs.2005.04.005  0.266
2012 Varshavsky A. Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis. Protein Science : a Publication of the Protein Society. 21: 1634-61. PMID 22930402 DOI: 10.1002/Pro.2148  0.263
1983 Wu KC, Strauss F, Varshavsky A. Nucleosome arrangement in green monkey alpha-satellite chromatin. Superimposition of non-random and apparently random patterns. Journal of Molecular Biology. 170: 93-117. PMID 6313939 DOI: 10.1016/S0022-2836(83)80228-9  0.252
1998 Varshavsky A. Codominant interference, antieffectors, and multitarget drugs. Proceedings of the National Academy of Sciences of the United States of America. 95: 2094-9. PMID 9482844 DOI: 10.1073/Pnas.95.5.2094  0.249
1987 Peck LJ, Millstein L, Eversole-Cire P, Gottesfeld JM, Varshavsky A. Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro. Molecular and Cellular Biology. 7: 3503-10. PMID 3683391 DOI: 10.1128/Mcb.7.10.3503  0.248
1984 Roninson IB, Abelson HT, Housman DE, Howell N, Varshavsky A. Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells. Nature. 309: 626-8. PMID 6728022 DOI: 10.1038/309626A0  0.248
1981 Varshavsky A. Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: possible mechanisms and relevance to tumor promotion. Cell. 25: 561-72. PMID 7285113 DOI: 10.1016/0092-8674(81)90074-X  0.242
1982 Boyce FM, Sundin O, Barsoum J, Varshavsky A. New way to isolate simian virus 40 nucleoprotein complexes from infected cells: use of a thiol-specific reagent. Journal of Virology. 42: 292-6. PMID 6283146 DOI: 10.1128/Jvi.42.1.292-296.1982  0.24
2004 Varshavsky A. 'Spalog' and 'sequelog': neutral terms for spatial and sequence similarity. Current Biology : Cb. 14: R181-3. PMID 15028230 DOI: 10.1016/J.Cub.2004.02.014  0.24
2014 Varshavsky A. Discovery of the biology of the ubiquitin system. Jama. 311: 1969-70. PMID 24846030 DOI: 10.1001/Jama.2014.5549  0.234
1983 Barsoum J, Varshavsky A. Mitogenic hormones and tumor promoters greatly increase the incidence of colony-forming cells bearing amplified dihydrofolate reductase genes. Proceedings of the National Academy of Sciences of the United States of America. 80: 5330-4. PMID 6351057 DOI: 10.1073/Pnas.80.17.5330  0.234
2003 Varshavsky A. Q & A: Alexander Varshavsky. Current Biology : Cb. 13: R501-2. PMID 12842020 DOI: 10.1016/S0960-9822(03)00436-6  0.218
1994 Sharp JD, Pickard RT, Chiou XG, Manetta JV, Kovacevic S, Miller JR, Varshavsky AD, Roberts EF, Strifler BA, Brems DN. Serine 228 is essential for catalytic activities of 85-kDa cytosolic phospholipase A2. The Journal of Biological Chemistry. 269: 23250-4. PMID 8083230  0.214
2006 Varshavsky A. Discovering the RNA double helix and hybridization. Cell. 127: 1295-7. PMID 17190591 DOI: 10.1016/J.Cell.2006.12.008  0.207
2000 Hershko A, Ciechanover A, Varshavsky A. Basic Medical Research Award. The ubiquitin system. Nature Medicine. 6: 1073-81. PMID 11017125 DOI: 10.1038/80384  0.2
1985 Barsoum J, Varshavsky A. Preferential localization of variant nucleosomes near the 5'-end of the mouse dihydrofolate reductase gene. The Journal of Biological Chemistry. 260: 7688-97. PMID 2987265  0.196
1983 Varshavsky A. Diadenosine 5', 5"'-P1, P4-tetraphosphate: a pleiotropically acting alarmone? Cell. 34: 711-2. PMID 6354469 DOI: 10.1016/0092-8674(83)90526-3  0.183
1982 Barsoum J, Levinger L, Varshavsky A. On the chromatin structure of the amplified, transcriptionally active gene for dihydrofolate reductase in mouse cells. The Journal of Biological Chemistry. 257: 5274-82. PMID 6896057  0.18
1991 Aniskin VM, Malygin VM, Varshavsky AA, Isaev SI. Chromosomes differentiation of spiny rats of the genus Proechimys (Rodentia, Echimyidae) Genetika. 27: 1431-1439. PMID 1761215  0.174
1978 Shmatchenko VV, Varshavsky AJ. A technique of low-pH gel electrophoresis of chromosomal proteins which does not require preliminary removal of DNA. Analytical Biochemistry. 85: 42-6. PMID 24369  0.173
1971 Ilyin YV, Varshavsky AY, Mickelsaar UN, Georgiev GP. Studies on deoxyribonucleoprotein structure. Redistribution of proteins in mixtures of deoxyribonucleoproteins, DNA and RNA. European Journal of Biochemistry / Febs. 22: 235-45. PMID 5116611  0.169
1981 Levinger L, Varshavsky A. Heat-shock proteins of Drosophila are associated with nuclease-resistant, high-salt-resistant nuclear structures. The Journal of Cell Biology. 90: 793-6. PMID 6793602  0.163
1979 Varshavsky AJ, Sundin O, Bohn M. A stretch of "late" SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes. Cell. 16: 453-66. PMID 222461  0.16
1973 Varshavsky AJ, Georgiev GP. Arrangement of histones along DNA in chromosomal deoxyribonucleoprotein lacking histone F1. Molecular Biology Reports. 1: 87-92. PMID 24197471 DOI: 10.1007/BF00357586  0.14
1978 Varshavsky AJ, Sundin OH, Bohn MJ. SV40 viral minichromosome: preferential exposure of the origin of replication as probed by restriction endonucleases. Nucleic Acids Research. 5: 3469-77. PMID 214758 DOI: 10.1093/nar/5.10.3469  0.139
1976 Varshavsky AJ, Bakayev VV, Georgiev GP. Heterogeneity of chromatin subunits in vitro and location of histone H1. Nucleic Acids Research. 3: 477-92. PMID 1257057  0.138
2008 Varshavsky A, Kessler O, Abramovitch S, Kigel B, Zaffryar S, Akiri G, Neufeld G. Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like pro-protein convertases. Cancer Research. 68: 6922-31. PMID 18757406 DOI: 10.1158/0008-5472.CAN-07-5408  0.126
1976 Varshavsky AJ, Georgiev GP. Free DNA stretches in histone H1-depleted chromatin and their possible relation to chromomere structure. Molecular Biology Reports. 3: 27-38. PMID 1004504  0.125
1973 Varshavsky AJ, Georgiev GP. Redistribution of histones during unfolding of chromosomal DNA. Molecular Biology Reports. 1: 143-8. PMID 24197509 DOI: 10.1007/BF00357154  0.123
1983 Varshavsky A, Barsoum J, Roninson I, Snapka R. Acquisition and loss of amplified genes: dramatic effects of hormones, tumor promoters and cytotoxic drugs. Princess Takamatsu Symposia. 14: 235-54. PMID 6394591  0.12
1975 Varshavsky AJ, Georgiev GP. Studies on chromatin. V. A model for the structure of chromatin subunit. Molecular Biology Reports. 2: 255-62. PMID 1196313  0.12
1977 Varshavsky AJ, Nedospasov SA, Schmatchenko VV, Bakayev VV, Chumackov PM, Georgiev GP. Compact form of SV40 viral minichromosome is resistant to nuclease: possible implications for chromatin structure. Nucleic Acids Research. 4: 3303-25. PMID 200892  0.119
2000 Varshavsky AD, Birnbaum DT, Beals JM, Saxberg BE. Global stochastic optimization in hierarchical modeling of ligand/protein binding profiles Kybernetes. 29: 452-472. DOI: 10.1108/03684920010322217  0.117
2023 Varshavsky A, Lewis K, Chen SJ. Deletions of DNA in cancer and their possible uses for therapy. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300051. PMID 37166062 DOI: 10.1002/bies.202300051  0.115
1973 Varshavsky AJ, Ilyin YV, Georgiev GP. Long molecules of free DNA in the sheared chromatin preparation. Molecular Biology Reports. 1: 201-7. PMID 24197567 DOI: 10.1007/BF00357642  0.109
1976 Varshavsky AJ, Bakayev VV, Chumackov PM, Georgiev GP. Minichromosome of simian virus 40: presence of histone HI. Nucleic Acids Research. 3: 2101-13. PMID 184438  0.106
1975 Varshavsky AJ, Bakayev VV. Studies on chromatin. III. v-Bodies and free DNA in chromatin lacking histone H1. Molecular Biology Reports. 2: 209-17. PMID 1196309  0.106
1976 Varshavsky AJ, Bakayev VV, Ilyin YV, Bayev AA, Georgiev GP. Studies on chromatin. Free DNA in sheared chromatin. European Journal of Biochemistry / Febs. 66: 211-23. PMID 947750  0.105
2007 Neufeld G, Lange T, Varshavsky A, Kessler O. Semaphorin signaling in vascular and tumor biology. Advances in Experimental Medicine and Biology. 600: 118-31. PMID 17607951 DOI: 10.1007/978-0-387-70956-7_10  0.1
1974 Varshavsky AJ, Ilyin YV, Georgiev GP. Very long stretches of free DNA in chromatin. Nature. 250: 602-6. PMID 4845662  0.099
1975 Varshavsky AJ, Bakayev VV. Studies on chromatin. IV. Evidence for a toroidal shape of chromatin subunits. Molecular Biology Reports. 2: 247-54. PMID 1196312  0.094
1978 Varshavsky AJ, Bakayev VV, Nedospasov SA, Georgiev GP. On the structure of eukaryotic, prokaryotic, and viral chromatin. Cold Spring Harbor Symposia On Quantitative Biology. 42: 457-73. PMID 209944  0.089
2011 Mathur S, Miller R, Varshavsky A, Trappe W, Mandayam N. ProxiMate: Proximity-based secure pairing using ambient wireless signals Mobisys'11 - Compilation Proceedings of the 9th International Conference On Mobile Systems, Applications and Services and Co-Located Workshops. 211-224. DOI: 10.1145/1999995.2000016  0.079
1978 Varshavsky AJ, Bakayev VV, Bakayeva TG, Chumackov PM, Shmatchenko VV, Georgiev GP. On the structure of cellular and viral chromatin. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 283: 275-85. PMID 26069  0.078
2011 Kigel B, Rabinowicz N, Varshavsky A, Kessler O, Neufeld G. Plexin-A4 promotes tumor progression and tumor angiogenesis by enhancement of VEGF and bFGF signaling. Blood. 118: 4285-96. PMID 21832283 DOI: 10.1182/blood-2011-03-341388  0.078
2007 Guttmann-Raviv N, Shraga-Heled N, Varshavsky A, Guimaraes-Sternberg C, Kessler O, Neufeld G. Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis. The Journal of Biological Chemistry. 282: 26294-305. PMID 17569671 DOI: 10.1074/jbc.M609711200  0.071
1972 Varshavsky AJ, Georgiev GP. Clustered arrangement of histones F2al and F3 along DNA in chromosomal deoxyribonucleoproteins. Biochimica Et Biophysica Acta. 281: 669-74. PMID 4653132  0.067
1974 Georgiev GP, Varshavsky AJ, Ryskov AP, Church RB. On the structural organization of the transcriptional unit in animal chromosomes. Cold Spring Harbor Symposia On Quantitative Biology. 38: 869-84. PMID 4524791  0.066
1996 Birnbaum DT, Dodd SW, Saxberg BE, Varshavsky AD, Beals JM. Hierarchical modeling of phenolic ligand binding to 2Zn--insulin hexamers. Biochemistry. 35: 5366-78. PMID 8611526 DOI: 10.1021/bi9600557  0.063
2008 Kigel B, Varshavsky A, Kessler O, Neufeld G. Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells. Plos One. 3: e3287. PMID 18818766 DOI: 10.1371/journal.pone.0003287  0.062
2010 Yang J, Varshavsky A, Liu H, Chen Y, Gruteser M. Accuracy characterization of cell tower localization Ubicomp'10 - Proceedings of the 2010 Acm Conference On Ubiquitous Computing. 223-226. DOI: 10.1145/1864349.1864384  0.061
2007 Varshavsky A, de Lara E, Hightower J, LaMarca A, Otsason V. GSM indoor localization Pervasive and Mobile Computing. 3: 698-720. DOI: 10.1016/J.Pmcj.2007.07.004  0.06
1974 Ilyin YV, Bayev AA, Zhuze AL, Varshavsky AJ. Histone-histone proximity in chromatin as seen by imidoester cross-linking. Molecular Biology Reports. 1: 343-8. PMID 4473704  0.059
2012 Miluzzo E, Varshavsky A, Balakrishnan S, Choudhury RR. Tapprints: Your finger taps have fingerprints Mobisys'12 - Proceedings of the 10th International Conference On Mobile Systems, Applications, and Services. 323-336. DOI: 10.1145/2307636.2307666  0.056
2010 Chandrasekaran G, Vu T, Varshavsky A, Gruteser M, Martin RP, Yang J, Chen Y. Vehicular speed estimation using received signal strength from mobile phones Ubicomp'10 - Proceedings of the 2010 Acm Conference On Ubiquitous Computing. 237-240. DOI: 10.1145/1864349.1864386  0.054
1995 Herron DK, Bollinger NG, Chaney MO, Varshavsky AD, Yost JB, Sherman WR, Thingvold JA. Visualization and comparison of molecular dynamics simulations of leukotriene C4, leukotriene D4, and leukotriene E4. Journal of Molecular Graphics. 13: 337-41. PMID 8820302 DOI: 10.1016/0263-7855(95)00081-X  0.052
2011 Chandrasekaran G, Vu T, Varshavsky A, Gruteser M, Martin RP, Yang J, Chen Y. Tracking vehicular speed variations by warping mobile phone signal strengths 2011 Ieee International Conference On Pervasive Computing and Communications, Percom 2011. 213-221. DOI: 10.1109/PERCOM.2011.5767589  0.052
2011 Javed U, Han D, Caceres R, Pang J, Seshan S, Varshavsky A. Predicting handoffs in 3G networks Proceedings of the 3rd Acm Sosp Workshop On Networking, Systems, and Applications On Mobile Handhelds, Mobiheld'11. DOI: 10.1145/2094091.2094109  0.052
2007 Varshavsky AA, Karimova TY, Neronov VM. Specific features of the rodent fauna formation in somali peninsula Zoologicheskii Zhurnal. 86: 1498-1506.  0.049
2011 Isaacman S, Becker R, Cáceres R, Kobourov S, Martonosi M, Rowland J, Varshavsky A. Identifying important places in people's lives from cellular network data Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6696: 133-151. DOI: 10.1007/978-3-642-21726-5_9  0.049
2011 Becker RA, Caceres R, Hanson K, Loh JM, Urbanek S, Varshavsky A, Volinsky C. Route classification using cellular handoff patterns Ubicomp'11 - Proceedings of the 2011 Acm Conference On Ubiquitous Computing. 123-132. DOI: 10.1145/2030112.2030130  0.049
2009 Scannell A, Varshavsky A, LaMarca A, de Lara E. Proximity-based authentication of mobile devices International Journal of Security and Networks. 4: 4-16. DOI: 10.1504/Ijsn.2009.023422  0.046
1991 Aniskin VM, Malygin VM, Varshavsky AA, Isaev SI. Karyological interrelations of three chromosomes forms of spiny rats of the genus Proechimys (Rodentia, Echimyidae) Genetika. 27: 1066-1075.  0.044
2012 Dyaberi JM, Parsons B, Pai V, Kannan K, Chen YF, Jana R, Stern D, Varshavsky A. Managing cellular congestion using incentives Ieee Communications Magazine. 50: 100-107. DOI: 10.1109/Mcom.2012.6353689  0.042
1991 Aniskin VM, Varshavsky AA, Isaev SI, Malygin VM. Comparative analysis of G- and C-banded chromosomes of five species of the Didelphidae (Marsupialia) family Genetika. 27: 504-514.  0.041
2013 Becker R, Ramón C, Hanson K, Isaacman S, Loh JM, Martonosi M, Rowland J, Urbanek S, Varshavsky A, Volinsky C. Human mobility characterization from cellular network data Communications of the Acm. 56: 74-82. DOI: 10.1145/2398356.2398375  0.041
2011 Isaacman S, Becker R, Caceres R, Kobourov S, Martonosi M, Rowland J, Varshavsky A. Ranges of human mobility in Los Angeles and New York 2011 Ieee International Conference On Pervasive Computing and Communications Workshops, Percom Workshops 2011. 88-93. DOI: 10.1109/PERCOMW.2011.5766977  0.035
1996 Varshavsky AI, Panchenko KI, Guberskaya TA, Varshavskaya AA. Comparative cunicomorphological characteristics of chronic parotitides in sarcoidosis and primary Sjogren's syndrome Terapevticheskii Arkhiv. 68: x4-41.  0.033
2012 Gember A, Akella A, Pang J, Varshavsky A, Caceres R. Obtaining in-context measurements of cellular network performance Proceedings of the Acm Sigcomm Internet Measurement Conference, Imc. 287-300. DOI: 10.1145/2398776.2398807  0.027
1999 Varshavsky AI, Panchenko KI, Guberskaya TA, Varshavskaya AA. Comparative sonographic, X-ray and morphological studies of the salivary glands in Sjogren's syndrome Terapevticheskii Arkhiv. 71: 61-67. PMID 10399235  0.025
2011 Liu D, Shakimov A, Cáceres R, Varshavsky A, Cox LP. Confidant: Protecting OSN data without locking it up Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7049: 61-80. DOI: 10.1007/978-3-642-25821-3_4  0.024
2012 Isaacman S, Becker R, Cáceres R, Martonosi M, Rowland J, Varshavsky A, Willinger W. Human mobility modeling at metropolitan scales Mobisys'12 - Proceedings of the 10th International Conference On Mobile Systems, Applications, and Services. 239-251. DOI: 10.1145/2307636.2307659  0.023
1977 Bakayev VV, Bakayeva TG, Varshavsky AJ. Nucleosomes and subnucleosomes: heterogeneity and composition. Cell. 11: 619-29. PMID 884737  0.023
2007 Varshavsky A, Scannell A, LaMarca A, De Lara E. Amigo: Proximity-based authentication of mobile devices Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4717: 253-270.  0.023
1997 Varshavsky AA, Neronov VM, Zhang YZ. Zoogeographical regionalization of arid areas of China (based on data on Rodents' distribution) Zoologicheskii Zhurnal. 76: 484-486.  0.022
2013 Bao X, Fan S, Varshavsky A, Li KA, Choudhury RR. Your reactions suggest you liked the movie: Automatic content rating via reaction sensing Ubicomp 2013 - Proceedings of the 2013 Acm International Joint Conference On Pervasive and Ubiquitous Computing. 197-206. DOI: 10.1145/2493432.2493440  0.022
2005 Otsason V, Varshavsky A, LaMarca A, De Lara E. Accurate GSM indoor localization Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 3660: 141-158.  0.021
2011 Becker RA, Cáceres R, Hanson K, Loh JM, Urbanek S, Varshavsky A, Volinsky C. A tale of one city: Using cellular network data for urban planning Ieee Pervasive Computing. 10: 18-26. DOI: 10.1109/MPRV.2011.44  0.02
2006 Varshavsky A, Lamarca A, Hightower J, De Lara E. The skyLoc floor localization system Proceedings - Fifth Annual Ieee International Conference On Pervasive Computing and Communications, Percom 2007. 125-134. DOI: 10.1109/PERCOM.2007.37  0.02
2008 Varshavsky A, Pankratov D, Krumm J, De Lara E. Calibree: Calibration-free localization using relative distance estimations Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5013: 146-161. DOI: 10.1007/978-3-540-79576-6_9  0.019
2020 Varshavsky AE, Vinokurova NA, Kochetkova EV. Scientists' ideas about what professions are the most suitable for their children and grandchildren Population. 23: 119-134. DOI: 10.19181/population.2020.23.1.10  0.019
2013 Agarwal S, Varshavsky A. Message from the chairs Acm Hotmobile 2013: the 14th Workshop On Mobile Computing Systems and Applications 0.018
2013 Schmidt A, Liu J, Roussos G, Varshavsky A. Editorial Pervasive and Mobile Computing. 9: 337-338. DOI: 10.1016/j.pmcj.2013.03.002  0.017
2006 Chen MY, Sohn T, Chmelev D, Haehnel D, Hightower J, Hughes J, LaMarca A, Potter F, Smith L, Varshavsky A. Practical metropolitan-scale positioning for GSM phones Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4206: 225-242.  0.014
2007 Varshavsky A, Lamarca A, De Lara E. Enabling secure and spontaneous communication between mobile devices using common radio environment Proceedings - 8th Ieee Workshop On Mobile Computing Systems and Applications, Hotmobile 2007. 9-13. DOI: 10.1109/WMCSA.2007.4389551  0.014
2005 Varshavsky A, Reid B, De Lara E. A cross-layer approach to service discovery and selection in MANETs 2nd Ieee International Conference On Mobile Ad-Hoc and Sensor Systems, Mass 2005. 2005: 459-466. DOI: 10.1109/MAHSS.2005.1542832  0.011
2011 Bickford J, Lagar-Cavilla HA, Varshavsky A, Ganapathy V, Iftode L. Security versus energy tradeoffs in host-based mobile malware detection Mobisys'11 - Compilation Proceedings of the 9th International Conference On Mobile Systems, Applications and Services and Co-Located Workshops. 225-238. DOI: 10.1145/1999995.2000017  0.011
2009 Markusova VA, Jansz M, Libkind AN, Libkind I, Varshavsky A. Trends in Russian research output in post-Soviet era Scientometrics. 79: 249-260. DOI: 10.1007/s11192-009-0416-0  0.011
2012 Schmidt A, Liu J, Roussos G, Varshavsky A. Welcome from the technical program chairs 2012 Ieee International Conference On Pervasive Computing and Communications, Percom 2012. iv. DOI: 10.1109/PerCom.2012.6199839  0.01
2011 Lagar-Cavilla HA, Joshi K, Varshavsky A, Bickford J, Parra D. Traffic backfilling: Subsidizing lunch for delay-tolerant applications in UMTS networks Proceedings of the 3rd Acm Sosp Workshop On Networking, Systems, and Applications On Mobile Handhelds, Mobiheld'11. DOI: 10.1145/2043106.2043117  0.01
2011 Shakimov A, Lim H, Cáceres R, Cox LP, Li K, Liu D, Varshavsky A. Vis-à-Vis: Privacy-preserving online social networking via Virtual Individual Servers 2011 3rd International Conference On Communication Systems and Networks, Comsnets 2011. DOI: 10.1109/COMSNETS.2011.5716497  0.01
2010 Isaacman S, Becker R, Cáceres R, Kobourov S, Rowland J, Varshavsky A. A tale of two cities Hotmobile 2010: the 11th Workshop On Mobile Computing Systems and Applications. 19-24. DOI: 10.1145/1734583.1734589  0.01
2007 Dearman D, Varshavsky A, De Lara E, Truong KN. An exploration of location error estimation Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4717: 181-198.  0.01
2006 Sohn T, Varshavsky A, LaMarca A, Chen MY, Choudhury T, Smith I, Consolvo S, Hightower J, Griswold WG, De Lara E. Mobility detection using everyday GSM traces Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4206: 212-224.  0.01
2004 Varshavsky A, De Lara E. Alleviating self-interference in MANETs Proceedings - Conference On Local Computer Networks, Lcn. 642-649. DOI: 10.1109/LCN.2004.14  0.01
2004 Varshavsky A, Li B, De Lara E. Cross-layer flow control in lightly-loaded multi-hop ad hoc networks Proceedings of the International Conference On Parallel Processing Workshops. 315-321. DOI: 10.1109/ICPPW.2004.1328033  0.01
2001 Varshavsky A. The 2000 Genetics Society of America Medal. Jack W. Szostak. Genetics. 157: 465-6. PMID 11370622  0.01
1971 Varshavsky AY, Ilyin YV, Kadyckov VI, Senchenkov EP. Collapse of extended deoxyribonucleoprotein molecules upon increase of the ionic strength of solution. Biochimica Et Biophysica Acta. 246: 583-8. PMID 5142075  0.01
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