Aaron Williams - Related publications

Physiology and Biophysics University of Washington, Seattle, Seattle, WA 
HCN channels
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Kim JE, Lee DS, Park H, Kim TH, Kang TC. Inhibition of AKT/GSK3β/CREB Pathway Improves the Responsiveness to AMPA Receptor Antagonists by Regulating GRIA1 Surface Expression in Chronic Epilepsy Rats. Biomedicines. 9. PMID 33919872 DOI: 10.3390/biomedicines9040425   
2021 Kato S, Porter R, Okamura R, Lee S, Zelichov O, Tarcic G, Vidne M, Kurzrock R. Functional measurement of mitogen-activated protein kinase pathway activation predicts responsiveness of RAS-mutant cancers to MEK inhibitors. European Journal of Cancer (Oxford, England : 1990). 149: 184-192. PMID 33865203 DOI: 10.1016/j.ejca.2021.01.055   
2021 Lin CC, Wieteska L, Suen KM, Kalverda AP, Ahmed Z, Ladbury JE. Grb2 binding induces phosphorylation-independent activation of Shp2. Communications Biology. 4: 437. PMID 33795832 DOI: 10.1038/s42003-021-01969-7   
2021 Girault JA, Nairn AC. DARPP-32 40 years later. Advances in Pharmacology (San Diego, Calif.). 90: 67-87. PMID 33706939 DOI: 10.1016/bs.apha.2020.09.004   
2021 Deng L, Huang X, Dong C, Ren J. Simultaneously monitoring endogenous MAPK members in single living cells by multi-channel fluorescence correlation spectroscopy. The Analyst. 146: 2581-2590. PMID 33899064 DOI: 10.1039/d1an00090j   
2021 Carriba P, Davies AM. How CD40L reverse signaling regulates axon and dendrite growth. Cellular and Molecular Life Sciences : Cmls. 78: 1065-1083. PMID 32506167 DOI: 10.1007/s00018-020-03563-2   
2021 Blazejewski SM, Bennison SA, Liu X, Toyo-Oka K. High-throughput kinase inhibitor screening reveals roles for Aurora and Nuak kinases in neurite initiation and dendritic branching. Scientific Reports. 11: 8156. PMID 33854138 DOI: 10.1038/s41598-021-87521-3   
2021 Baffi TR, Lordén G, Wozniak JM, Feichtner A, Yeung W, Kornev AP, King CC, Del Rio JC, Limaye AJ, Bogomolovas J, Gould CM, Chen J, Kennedy EJ, Kannan N, Gonzalez DJ, et al. mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. Science Signaling. 14. PMID 33850054 DOI: 10.1126/scisignal.abe4509   
2021 Liu T, Lv YF, Zhao JL, You QD, Jiang ZY. Regulation of Nrf2 by phosphorylation: consequences for biological function and therapeutic implications. Free Radical Biology & Medicine. PMID 33794311 DOI: 10.1016/j.freeradbiomed.2021.03.034   
2021 Fleischmann J, Feichtner A, DeFalco L, Kugler V, Schwaighofer S, Huber RG, Stefan E. Allosteric Kinase Inhibitors Reshape MEK1 Kinase Activity Conformations in Cells and In Silico. Biomolecules. 11. PMID 33808483 DOI: 10.3390/biom11040518   
2021 Wu K, Han W, Tian Q, Li Y, Lu W. Activity- and sleep-dependent regulation of tonic inhibition by Shisa7. Cell Reports. 34: 108899. PMID 33761345 DOI: 10.1016/j.celrep.2021.108899   
2021 Bußmann L, Hoffer K, von Bargen CM, Droste C, Lange T, Kemmling J, Schröder-Schwarz J, Vu AT, Akingunsade L, Nollau P, Rangarajan S, de Wijn R, Oetting A, Müller C, Böckelmann LC, et al. Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src-family kinases as prognostic markers and potential targets. International Journal of Cancer. PMID 33890294 DOI: 10.1002/ijc.33606   
2021 Guo X, Mao R, Cui L, Wang F, Zhou R, Wang Y, Huang J, Zhu Y, Yao Y, Zhao G, Li Z, Chen J, Wang J, Fang Y. PAID study design on the role of PKC activation in immune/inflammation-related depression: a randomised placebo-controlled trial protocol. General Psychiatry. 34: e100440. PMID 33912799 DOI: 10.1136/gpsych-2020-100440   
2021 Wu W, Wang X, Sun Y, Berleth N, Deitersen J, Schlütermann D, Stuhldreier F, Wallot-Hieke N, José Mendiburo M, Cox J, Peter C, Bergmann AK, Stork B. TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy. Autophagy. 1-18. PMID 33779513 DOI: 10.1080/15548627.2021.1899667   
2021 Wu W, Wang X, Sun Y, Berleth N, Deitersen J, Schlütermann D, Stuhldreier F, Wallot-Hieke N, José Mendiburo M, Cox J, Peter C, Bergmann AK, Stork B. TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy. Autophagy. 1-18. PMID 33779513 DOI: 10.1080/15548627.2021.1899667   
2021 Dragoni S, Caridi B, Karatsai E, Burgoyne T, Sarker MH, Turowski P. AMP-activated protein kinase is a key regulator of acute neurovascular permeability. Journal of Cell Science. PMID 33712448 DOI: 10.1242/jcs.253179   
2021 Hou TY, Wu SB, Kau HC, Tsai CC. JNK and p38 Inhibitors Prevent Transforming Growth Factor-β1-Induced Myofibroblast Transdifferentiation in Human Graves' Orbital Fibroblasts. International Journal of Molecular Sciences. 22. PMID 33799469 DOI: 10.3390/ijms22062952   
2021 Kerjouan A, Boyault C, Oddou C, Hiriart-Bryant E, Grichine A, Kraut A, Pezet M, Balland M, Faurobert E, Bonnet I, Coute Y, Fourcade B, Albiges-Rizo C, Destaing O. Control of SRC molecular dynamics encodes distinct cytoskeletal responses by specifying signaling pathway usage. Journal of Cell Science. 134. PMID 33495358 DOI: 10.1242/jcs.254599   
2021 Lee SY. Anti-Metastatic and Anti-Inflammatory Effects of Matrix Metalloproteinase Inhibition by Ginsenosides. Biomedicines. 9. PMID 33671187 DOI: 10.3390/biomedicines9020198   
2021 Boecker CA, Goldsmith J, Dou D, Cajka GG, Holzbaur ELF. Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes. Current Biology : Cb. PMID 33765413 DOI: 10.1016/j.cub.2021.02.061   
2021 Yu YH, Lai YH, Hsiao FS, Cheng YH. Effects of Deoxynivalenol and Mycotoxin Adsorbent Agents on Mitogen-Activated Protein Kinase Signaling Pathways and Inflammation-Associated Gene Expression in Porcine Intestinal Epithelial Cells. Toxins. 13. PMID 33922863 DOI: 10.3390/toxins13050301   
2021 Suk Nam G, Kim S, Kwon YS, Kim MK, Nam KS. A new function for MAP4K4 inhibitors during platelet aggregation and platelet-mediated clot retraction. Biochemical Pharmacology. 114519. PMID 33737052 DOI: 10.1016/j.bcp.2021.114519   
2021 Tóth E, Erdődi F, Kiss A. Myosin Phosphatase Is Implicated in the Control of THP-1 Monocyte to Macrophage Differentiation. International Journal of Molecular Sciences. 22. PMID 33802280 DOI: 10.3390/ijms22052516   
2021 Zhao Q, Liu F, Zhao Q, Zhang J, Luo J, Li X, Yang Y. Constitutive activation of ERK1/2 signaling protects against myocardial ischemia via inhibition of mitochondrial fragmentation in the aging heart. Annals of Translational Medicine. 9: 479. PMID 33850876 DOI: 10.21037/atm-21-503   
2021 Ibrahim SSA, Huttunen KM. Orchestrated modulation of rheumatoid arthritis via crosstalking intracellular signaling pathways. Inflammopharmacology. PMID 33740220 DOI: 10.1007/s10787-021-00800-3   
2021 Tsai YC, Huang CY, Hsueh YM, Fan YC, Fong YC, Huang SP, Geng JH, Chen LC, Lu TL, Bao BY. Genetic variants in MAPK10 modify renal cell carcinoma susceptibility and clinical outcomes. Life Sciences. 275: 119396. PMID 33774030 DOI: 10.1016/j.lfs.2021.119396   
2021 Wang D, Wang H, Liu Q, Tu R, Zhou X, Zhang Y, Wu W, Yu P, Chen D, Zhan X, Cao L, Cheng S, Shen X. Reduction of OsMPK6 activity by a R89K mutation induces cell death and bacterial blight resistance in rice. Plant Cell Reports. PMID 33730215 DOI: 10.1007/s00299-021-02679-4   
2021 Wei X, Lan T, Zhou Y, Cheng J, Li P, Zeng X, Yang Y. Mechanism of α1-Adrenergic Receptor-Induced Increased Contraction of Rat Mesenteric Artery in Aging Hypertension Rats. Gerontology. 1-15. PMID 33752204 DOI: 10.1159/000511911   
2021 Zhang DD, Zhang CY, Zhang YX, Cui HP, Chen J, Ma WZ, Jia H. G-CSF reduces loss of dopaminergic neurons by inhibiting TNF-α and IL-1β in mouse model of Parkinson's disease. The International Journal of Neuroscience. 1-12. PMID 33781148 DOI: 10.1080/00207454.2021.1910259   
2021 Wagner SA, Szczesniak PP, Voigt A, Gräf JF, Beli P. Proteomic analysis of tyrosine phosphorylation induced by exogenous expression of oncogenic kinase fusions identified in lung adenocarcinoma. Proteomics. e2000283. PMID 33768672 DOI: 10.1002/pmic.202000283   
2021 Deng Y, Liu B, Fu C, Gao L, Shen Y, Liu K, Li Q, Cao J, Mao W. Lipopolysaccharide stimulates bovine endometrium explants through toll‑like receptor 4 signaling and PGE synthesis. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 168: 102272. PMID 33895679 DOI: 10.1016/j.plefa.2021.102272   
2021 Ferreira APA, Casamento A, Carrillo Roas S, Halff EF, Panambalana J, Subramaniam S, Schützenhofer K, Chan Wah Hak L, McGourty K, Thalassinos K, Kittler JT, Martinvalet D, Boucrot E. Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosis. Nature Communications. 12: 2424. PMID 33893293 DOI: 10.1038/s41467-021-22603-4   
2021 Le Large TYS, Bijlsma MF, El Hassouni B, Mantini G, Lagerweij T, Henneman AA, Funel N, Kok B, Pham TV, de Haas R, Morelli L, Knol JC, Piersma SR, Kazemier G, van Laarhoven HWM, et al. Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma. Journal of Experimental & Clinical Cancer Research : Cr. 40: 91. PMID 33750427 DOI: 10.1186/s13046-021-01892-z   
2021 Worby CA, Mayfield JE, Pollak AJ, Dixon JE, Banerjee S. The ABCs of the atypical Fam20 secretory pathway kinases. The Journal of Biological Chemistry. 296: 100267. PMID 33759783 DOI: 10.1016/j.jbc.2021.100267   
2021 Park JY, Sohn HY, Koh YH, Jo C. Curcumin activates Nrf2 through PKCδ-mediated p62 phosphorylation at Ser351. Scientific Reports. 11: 8430. PMID 33875681 DOI: 10.1038/s41598-021-87225-8   
2021 Ashraf U, Ding Z, Deng S, Ye J, Cao S, Chen Z. Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage. Virulence. 12: 968-980. PMID 33724154 DOI: 10.1080/21505594.2021.1899674   
2021 Cho E, Lou HJ, Kuruvilla L, Calderwood DA, Turk BE. PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK. Cell Reports. 34: 108928. PMID 33789117 DOI: 10.1016/j.celrep.2021.108928   
2021 Higuchi M, Ishiyama K, Maruoka M, Kanamori R, Takaori-Kondo A, Watanabe N. Paradoxical activation of c-Src as a drug-resistant mechanism. Cell Reports. 34: 108876. PMID 33761359 DOI: 10.1016/j.celrep.2021.108876   
2021 Zhang Z, Tian S, Wu C, Yan L, Wan J, Zhang J, Liu X, Zhang W. Comprehensive bioinformatics analysis reveals kinase activity profiling associated with heart failure. Journal of Cellular Biochemistry. PMID 33899242 DOI: 10.1002/jcb.29935   
2021 Cho YS, Jiang J. Hippo-Independent Regulation of Yki/Yap/Taz: A Non-canonical View. Frontiers in Cell and Developmental Biology. 9: 658481. PMID 33869224 DOI: 10.3389/fcell.2021.658481   
2021 Rashmi, More SK, Wang Q, Vomhof-DeKrey EE, Porter JE, Basson MD. ZINC40099027 activates human focal adhesion kinase by accelerating the enzymatic activity of the FAK kinase domain. Pharmacology Research & Perspectives. 9: e00737. PMID 33715263 DOI: 10.1002/prp2.737   
2021 Sun Z, Sun W, Pan B, Yao Y, Yan C. Molecular characterization of a novel p38 MAPK cDNA from Cyclina sinensis and its potential immune-related function under the threat of Vibrio anguillarum. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 110599. PMID 33845220 DOI: 10.1016/j.cbpb.2021.110599   
2021 Dong R, Xue Z, Fan G, Zhang N, Wang C, Li G, Da Y. Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock. Frontiers in Immunology. 12: 620238. PMID 33717117 DOI: 10.3389/fimmu.2021.620238   
2021 Arveseth CD, Happ JT, Hedeen DS, Zhu JF, Capener JL, Klatt Shaw D, Deshpande I, Liang J, Xu J, Stubben SL, Nelson IB, Walker MF, Kawakami K, Inoue A, Krogan NJ, et al. Smoothened transduces hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. Plos Biology. 19: e3001191. PMID 33886552 DOI: 10.1371/journal.pbio.3001191   
2021 Gong YT, Wu MY, Tang JF, Shen JC, Li J, Gao R, Dang BQ, Chen G. Advances in the study of the role and molecular mechanism of with‑no‑lysine kinase 3 in nervous system diseases (Review). Molecular Medicine Reports. 23. PMID 33760209 DOI: 10.3892/mmr.2021.12032   
2021 Huang N, Huang J, Zhang Y, Chen M, Shi J, Jin F. Resveratrol against 6-OHDA-induced damage of PC12 cells via PI3K/Akt. Translational Neuroscience. 12: 138-144. PMID 33976931 DOI: 10.1515/tnsci-2020-0165   
2021 Darling NJ, Cohen P. Nuts and bolts of the salt-inducible kinases (SIKs). The Biochemical Journal. 478: 1377-1397. PMID 33861845 DOI: 10.1042/BCJ20200502   
2021 Chen Z, Zhang Y, Wu X, Zhang J, Xu W, Shen C, Zheng B. Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma. Oncotargets and Therapy. 14: 2941-2952. PMID 33976552 DOI: 10.2147/OTT.S298102   
2021 Christensen KR, Nairn AC. cAMP-regulated phosphoproteins DARPP-32, ARPP16/19, and RCS modulate striatal signal transduction through protein kinases and phosphatases. Advances in Pharmacology (San Diego, Calif.). 90: 39-65. PMID 33706938 DOI: 10.1016/bs.apha.2020.09.005   
2021 Abdelrahman KS, Hassan HA, Abdel-Aziz SA, Marzouk AA, Narumi A, Konno H, Abdel-Aziz M. JNK signaling as a target for anticancer therapy. Pharmacological Reports : Pr. PMID 33710509 DOI: 10.1007/s43440-021-00238-y