| Year |
Citation |
Score |
| 2022 |
Perkins RS, Davis A, Campagne O, Owens TS, Stewart CF. CNS penetration of methotrexate and its metabolite 7-hydroxymethotrexate in mice bearing orthotopic Group 3 medulloblastoma tumors and model-based simulations for children. Drug Metabolism and Pharmacokinetics. 100471. PMID 36669926 DOI: 10.1016/j.dmpk.2022.100471 |
0.317 |
|
| 2020 |
Benzel J, Sauter M, Mack N, Davis A, Weiss J, Uhl P, Burhenne J, Maass KK, Hübner J, Witt H, Shelat A, Gajjar A, Upadhyaya SA, Camgoz A, Buchholz F, ... ... Stewart C, et al. Abstract A25: Evaluation of Drug Disposition in Supratentorial Ependymoma Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-A25 |
0.424 |
|
| 2019 |
Stewart C, Campagne O, Davis A, Zhong B, Nair S, Haberman V, T Patel Y, Janke L, F Roussel M. CNS Penetration of Cyclophosphamide and Metabolites in Mice Bearing Group 3 Medulloblastoma and Non-Tumor Bearing Mice. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, Societe Canadienne Des Sciences Pharmaceutiques. 22: 612-629. PMID 31815662 DOI: 10.18433/Jpps30608 |
0.378 |
|
| 2019 |
Campagne O, Davis A, Maharaj AR, Zhong B, Stripay J, Farmer D, Roussel MF, Stewart CF. CNS penetration and pharmacodynamics of the CHK1 inhibitor prexasertib in a mouse Group 3 medulloblastoma model. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105106. PMID 31669383 DOI: 10.1016/J.Ejps.2019.105106 |
0.333 |
|
| 2017 |
Jones Z, Roberts J, Houke H, Roussel M, Stewart C, Panetta C. Abstract 314: Evaluation of effective drug combinations of sonidegib and ribociclib for treatment of Sonic hedgehog medulloblastoma using mathematical models of the cell cycle and Hedgehog pathways Cancer Research. 77: 314-314. DOI: 10.1158/1538-7445.Am2017-314 |
0.382 |
|
| 2015 |
Morfouace M, Nimmervoll B, Boulos N, Patel YT, Shelat A, Freeman BB, Robinson GW, Wright K, Gajjar A, Stewart CF, Gilbertson RJ, Roussel MF. Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors. Journal of Neuro-Oncology. PMID 26518542 DOI: 10.1007/S11060-015-1965-0 |
0.328 |
|
| 2015 |
Jacus MO, Daryani VM, Harstead KE, Patel YT, Throm SL, Stewart CF. Pharmacokinetic Properties of Anticancer Agents for the Treatment of Central Nervous System Tumors: Update of the Literature. Clinical Pharmacokinetics. PMID 26293618 DOI: 10.1007/s40262-015-0319-6 |
0.322 |
|
| 2015 |
Morfouace M, Cheepala S, Jackson S, Fukuda Y, Patel YT, Fatima S, Kawauchi D, Shelat AA, Stewart CF, Sorrentino BP, Schuetz JD, Roussel MF. ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy. Cancer Research. PMID 26199091 DOI: 10.1158/0008-5472.Can-15-0030 |
0.307 |
|
| 2015 |
Panetta JC, Baker SD, Kantarjian HM, Stewart C, Pond B, Macaraeg M, Makinde T, Vali S, Daver N, Ramachandran A, Collins R, Cortes JE. Population Pharmacokinetics of Crenolanib, a Type I FLT3 Inhibitor, in Patients with Relapsed/Refractory AML Blood. 126: 3695-3695. DOI: 10.1182/Blood.V126.23.3695.3695 |
0.313 |
|
| 2015 |
Morfouace M, Patel Y, Shelat A, Kawauchi D, Robinson GW, Guy K, Gilbertson RJ, Stewart C, Gajjar A, Roussel MF. Abstract IA21: Pediatric medulloblastoma: Drug screens and preclinical studies Brain. 75. DOI: 10.1158/1538-7445.Brain15-Ia21 |
0.375 |
|
| 2015 |
Phoenix T, Patmore D, Boop S, Jacus M, Patel Y, Goumnerova L, Perreault S, Wadhwa E, Cho Y, Stewart C, Gilbertson R. MB-19 * MEDULLOBLASTOMA SUBTYPES SPECIFY INTER-TUMORAL VASCULAR BLOOD BRAIN BARRIER HETEROGENEITY Neuro-Oncology. 17: iii24-iii24. DOI: 10.1093/Neuonc/Nov061.95 |
0.378 |
|
| 2014 |
Stewart CF, Tagen M, Schwartzberg LS, Blakely LJ, Tauer KW, Smiley LM. Phase I dosage finding and pharmacokinetic study of intravenous topotecan and oral erlotinib in adults with refractory solid tumors. Cancer Chemotherapy and Pharmacology. 73: 561-8. PMID 24448640 DOI: 10.1007/s00280-014-2385-0 |
0.335 |
|
| 2014 |
Jacus MO, Throm SL, Turner DC, Patel YT, Freeman BB, Morfouace M, Boulos N, Stewart CF. Deriving therapies for children with primary CNS tumors using pharmacokinetic modeling and simulation of cerebral microdialysis data. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 57: 41-7. PMID 24269626 DOI: 10.1016/j.ejps.2013.11.010 |
0.304 |
|
| 2013 |
Blaney SM, Tagen M, Onar-Thomas A, Berg SL, Gururangan S, Scorsone K, Su J, Goldman S, Kieran MW, Kun L, Boyett J, Stewart C. A phase-1 pharmacokinetic optimal dosing study of intraventricular topotecan for children with neoplastic meningitis: a Pediatric Brain Tumor Consortium study. Pediatric Blood & Cancer. 60: 627-32. PMID 23002039 DOI: 10.1002/Pbc.24309 |
0.31 |
|
| 2011 |
Elmeliegy MA, Carcaboso AM, L Chow LM, Zhang ZM, Calabrese C, Throm SL, Wang F, Baker SJ, Stewart CF. Magnetic resonance imaging-guided microdialysis cannula implantation in a spontaneous high-grade glioma murine model. Journal of Pharmaceutical Sciences. 100: 4210-4. PMID 21837651 DOI: 10.1002/Jps.22723 |
0.686 |
|
| 2011 |
Elmeliegy MA, Carcaboso AM, Tagen M, Bai F, Stewart CF. Role of ATP-binding cassette and solute carrier transporters in erlotinib CNS penetration and intracellular accumulation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 89-99. PMID 21088257 DOI: 10.1158/1078-0432.CCR-10-1934 |
0.7 |
|
| 2011 |
Nemeth KM, Federico S, Carcaboso AM, Shen Y, Schaiquevich P, Zhang J, Egorin M, Stewart C, Dyer MA. Subconjunctival carboplatin and systemic topotecan treatment in preclinical models of retinoblastoma. Cancer. 117: 421-34. PMID 20818652 DOI: 10.1002/Cncr.25574 |
0.33 |
|
| 2011 |
Elmeliegy M, Bai F, Juel S, Throm S, Ramachandran A, Stewart C. Abstract 5474: Optimization of a microdialysis method for evaluation of CP-868,596 penetration in glioblastoma murine models using a sensitive liquid chromatography mass spectrometry (LC-MS/MS) method Cancer Research. 71: 5474-5474. DOI: 10.1158/1538-7445.Am2011-5474 |
0.702 |
|
| 2010 |
Beaty O, Berg S, Blaney S, Malogolowkin M, Krailo M, Knight R, Schaiquevich P, Stewart C, Chen Z, Nelson M, Voss S, Ivy SP, Adamson PC. A phase II trial and pharmacokinetic study of oxaliplatin in children with refractory solid tumors: a Children's Oncology Group study. Pediatric Blood & Cancer. 55: 440-5. PMID 20658614 DOI: 10.1002/Pbc.22544 |
0.37 |
|
| 2010 |
Tagen M, Zhuang Y, Zhang F, Harstead KE, Shen J, Schaiquevich P, Fraga CH, Panetta JC, Waters CM, Stewart CF. P-glycoprotein, but not multidrug resistance protein 4, plays a role in the systemic clearance of irinotecan and SN-38 in mice. Drug Metabolism Letters. 4: 195-201. PMID 20583968 DOI: 10.2174/187231210792928251 |
0.689 |
|
| 2010 |
Carcaboso AM, Elmeliegy MA, Shen J, Juel SJ, Zhang ZM, Calabrese C, Tracey L, Waters CM, Stewart CF. Tyrosine kinase inhibitor gefitinib enhances topotecan penetration of gliomas. Cancer Research. 70: 4499-508. PMID 20460504 DOI: 10.1158/0008-5472.Can-09-4264 |
0.729 |
|
| 2009 |
Shen J, Carcaboso AM, Hubbard KE, Tagen M, Wynn HG, Panetta JC, Waters CM, Elmeliegy MA, Stewart CF. Compartment-specific roles of ATP-binding cassette transporters define differential topotecan distribution in brain parenchyma and cerebrospinal fluid. Cancer Research. 69: 5885-92. PMID 19567673 DOI: 10.1158/0008-5472.Can-09-0700 |
0.725 |
|
| 2009 |
Wilson MW, Fraga CH, Rodriguez-Galindo C, Hagedorn N, Leggas ML, Stewart C. Expression of the multi-drug resistance proteins and the pregnane X receptor in treated and untreated retinoblastoma. Current Eye Research. 34: 386-94. PMID 19401882 DOI: 10.1080/02713680902859621 |
0.628 |
|
| 2008 |
Schwartzberg LS, Stewart CF, Schaiquevich P, Legenne P, Bhatt K, Johns A, Walker MS. Phase I dosage-finding and pharmacokinetic (PK) study of intravenous topotecan and oral erlotinib in patients (pts) with refractory solid tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 2549. PMID 27947939 DOI: 10.1200/jco.2008.26.15_suppl.2549 |
0.303 |
|
| 2008 |
Narang VS, Fraga C, Kumar N, Shen J, Throm S, Stewart CF, Waters CM. Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier. American Journal of Physiology. Cell Physiology. 295: C440-50. PMID 18524938 DOI: 10.1152/Ajpcell.00491.2007 |
0.346 |
|
| 2007 |
Takenaka K, Morgan JA, Scheffer GL, Adachi M, Stewart CF, Sun D, Leggas M, Ejendal KF, Hrycyna CA, Schuetz JD. Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution. Cancer Research. 67: 6965-72. PMID 17638908 DOI: 10.1158/0008-5472.Can-06-4720 |
0.659 |
|
| 2006 |
Zhuang Y, Fraga CH, Hubbard KE, Hagedorn N, Panetta JC, Waters CM, Stewart CF. Topotecan central nervous system penetration is altered by a tyrosine kinase inhibitor. Cancer Research. 66: 11305-13. PMID 17145877 DOI: 10.1158/0008-5472.Can-06-0929 |
0.709 |
|
| 2006 |
Fouladi M, Blaney SM, Poussaint TY, Freeman BB, McLendon R, Fuller C, Adesina AM, Hancock ML, Danks MK, Stewart C, Boyett JM, Gajjar A. Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors: a pediatric brain tumor consortium study. Cancer. 107: 2291-7. PMID 17019740 DOI: 10.1002/Cncr.22241 |
0.335 |
|
| 2006 |
Motl S, Zhuang Y, Waters CM, Stewart CF. Pharmacokinetic considerations in the treatment of CNS tumours. Clinical Pharmacokinetics. 45: 871-903. PMID 16928151 DOI: 10.2165/00003088-200645090-00002 |
0.711 |
|
| 2006 |
Leggas M, Panetta JC, Zhuang Y, Schuetz JD, Johnston B, Bai F, Sorrentino B, Zhou S, Houghton PJ, Stewart CF. Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo. Cancer Research. 66: 4802-7. PMID 16651435 DOI: 10.1158/0008-5472.Can-05-2915 |
0.759 |
|
| 2006 |
Wilson MW, Fraga CH, Fuller CE, Rodriguez-Galindo C, Mancini J, Hagedorn N, Leggas ML, Stewart CF. Immunohistochemical detection of multidrug-resistant protein expression in retinoblastoma treated by primary enucleation. Investigative Ophthalmology & Visual Science. 47: 1269-73. PMID 16565357 DOI: 10.1167/Iovs.05-1321 |
0.606 |
|
| 2005 |
Laurie NA, Gray JK, Zhang J, Leggas M, Relling M, Egorin M, Stewart C, Dyer MA. Topotecan combination chemotherapy in two new rodent models of retinoblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7569-78. PMID 16243833 DOI: 10.1158/1078-0432.Ccr-05-0849 |
0.642 |
|
| 2004 |
Stewart CF, Leggas M, Schuetz JD, Panetta JC, Cheshire PJ, Peterson J, Daw N, Jenkins JJ, Gilbertson R, Germain GS, Harwood FC, Houghton PJ. Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice. Cancer Research. 64: 7491-9. PMID 15492275 DOI: 10.1158/0008-5472.Can-04-0096 |
0.669 |
|
| 2004 |
Leggas M, Adachi M, Scheffer GL, Sun D, Wielinga P, Du G, Mercer KE, Zhuang Y, Panetta JC, Johnston B, Scheper RJ, Stewart CF, Schuetz JD. Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Molecular and Cellular Biology. 24: 7612-21. PMID 15314169 DOI: 10.1128/Mcb.24.17.7612-7621.2004 |
0.761 |
|
| 2004 |
Leggas M, Zhuang Y, Welden J, Self Z, Waters CM, Stewart CF. Microbore HPLC method with online microdialysis for measurement of topotecan lactone and carboxylate in murine CSF. Journal of Pharmaceutical Sciences. 93: 2284-95. PMID 15295789 DOI: 10.1002/Jps.20134 |
0.716 |
|
| 2004 |
Benjamin RK, Hochberg FH, Fox E, Bungay PM, Elmquist WF, Stewart CF, Gallo JM, Collins JM, Pelletier RP, de Groot JF, Hickner RC, Cavus I, Grossman SA, Colvin OM. Review of microdialysis in brain tumors, from concept to application: first annual Carolyn Frye-Halloran symposium. Neuro-Oncology. 6: 65-74. PMID 14769143 DOI: 10.1215/S1152851703000103 |
0.308 |
|
| 2002 |
Leggas M, Stewart CF, Woo MH, Fouladi M, Cheshire PJ, Peterson JK, Friedman HS, Billups C, Houghton PJ. Relation between Irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3000-7. PMID 12231547 |
0.628 |
|
| 1999 |
Reardon D, Santana V, Stewart C, Thompson S, Ma M, Furnam W, Pratt C, Spunt C, Houghton P. #552 Pharmacokinetically-dosed topotecan (TPT) 5 days/week for 2 consecutive weeks and weekly vincristine (Vcr) given to children with relapsed solid tumors Journal of Pediatric Hematology/Oncology. 21: 338. DOI: 10.1097/00043426-199907000-00136 |
0.321 |
|
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