Jayanth S. Chandran, Ph.D. - Publications

Affiliations: 
2008 Johns Hopkins University, Baltimore, MD 
Area:
Neuroscience Biology

14/25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Lai C, Xie C, Shim H, Chandran J, Howell BW, Cai H. Regulation of endosomal motility and degradation by amyotrophic lateral sclerosis 2/alsin. Molecular Brain. 2: 23. PMID 19630956 DOI: 10.1186/1756-6606-2-23  0.574
2008 Cai H, Shim H, Lai C, Xie C, Lin X, Yang WJ, Chandran J. ALS2/alsin knockout mice and motor neuron diseases. Neuro-Degenerative Diseases. 5: 359-66. PMID 18714162 DOI: 10.1159/000151295  0.637
2008 van der Brug MP, Blackinton J, Chandran J, Hao LY, Lal A, Mazan-Mamczarz K, Martindale J, Xie C, Ahmad R, Thomas KJ, Beilina A, Gibbs JR, Ding J, Myers AJ, Zhan M, et al. RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 10244-9. PMID 18626009 DOI: 10.1073/Pnas.0708518105  0.53
2008 Wang L, Xie C, Greggio E, Parisiadou L, Shim H, Sun L, Chandran J, Lin X, Lai C, Yang WJ, Moore DJ, Dawson TM, Dawson VL, Chiosis G, Cookson MR, et al. The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3384-91. PMID 18367605 DOI: 10.1523/Jneurosci.0185-08.2008  0.649
2008 Wang Y, Chandran JS, Cai H, Mattson MP. DJ-1 is essential for long-term depression at hippocampal CA1 synapses. Neuromolecular Medicine. 10: 40-5. PMID 18246449 DOI: 10.1007/S12017-008-8023-4  0.619
2008 Chandran JS, Lin X, Zapata A, Höke A, Shimoji M, Moore SO, Galloway MP, Laird FM, Wong PC, Price DL, Bailey KR, Crawley JN, Shippenberg T, Cai H. Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function. Neurobiology of Disease. 29: 505-14. PMID 18187333 DOI: 10.1016/J.Nbd.2007.11.011  0.667
2008 Jellinger KA, Debatin L, Streffer J, Geissen M, Matschke J, Aguzzi A, Glatzel M, Papapetropoulos S, Argyriou AA, Polychronopoulos P, Spyridonidis T, Gourzis P, Chroni E, Cai H, Shim H, ... ... Chandran J, et al. Contents Vol. 5, 2008 Neurodegenerative Diseases. 5. DOI: 10.1159/000155242  0.413
2008 Jellinger KA, Debatin L, Streffer J, Geissen M, Matschke J, Aguzzi A, Glatzel M, Papapetropoulos S, Argyriou AA, Polychronopoulos P, Spyridonidis T, Gourzis P, Chroni E, Cai H, Shim H, ... ... Chandran J, et al. Subject Index Vol. 5, 2008 Neurodegenerative Diseases. 5: 369-370. DOI: 10.1159/000155229  0.422
2007 Lai C, Lin X, Chandran J, Shim H, Yang WJ, Cai H. The G59S mutation in p150(glued) causes dysfunction of dynactin in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13982-90. PMID 18094236 DOI: 10.1523/Jneurosci.4226-07.2007  0.616
2007 Chandran J, Ding J, Cai H. Alsin and the molecular pathways of amyotrophic lateral sclerosis. Molecular Neurobiology. 36: 224-31. PMID 17955197 DOI: 10.1007/S12035-007-0034-X  0.595
2007 van de Leemput J, Chandran J, Knight MA, Holtzclaw LA, Scholz S, Cookson MR, Houlden H, Gwinn-Hardy K, Fung HC, Lin X, Hernandez D, Simon-Sanchez J, Wood NW, Giunti P, Rafferty I, et al. Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. Plos Genetics. 3: e108. PMID 17590087 DOI: 10.1371/Journal.Pgen.0030108  0.574
2006 Lai C, Xie C, McCormack SG, Chiang HC, Michalak MK, Lin X, Chandran J, Shim H, Shimoji M, Cookson MR, Huganir RL, Rothstein JD, Price DL, Wong PC, Martin LJ, et al. Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11798-806. PMID 17093100 DOI: 10.1523/Jneurosci.2084-06.2006  0.639
2005 Leemput JVd, Chandran J, Knight M, Holtzclaw L, Scholz S, Cookson MR, Houlden H, Gwinn K, Fung P, Lin X, Hernandez DG, Simon-Sanchez J, Wood N, Rafferty I, Hardy J, et al. Deletion at ITPR1 underlies ataxia in mice and humans (SCA15) Plos Genetics. DOI: 10.1371/Journal.Pgen.0030108.Eor  0.527
2003 Miller DW, Ahmad R, Hague S, Baptista MJ, Canet-Aviles R, McLendon C, Carter DM, Zhu PP, Stadler J, Chandran J, Klinefelter GR, Blackstone C, Cookson MR. L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system. The Journal of Biological Chemistry. 278: 36588-95. PMID 12851414 DOI: 10.1074/Jbc.M304272200  0.358
Low-probability matches (unlikely to be authored by this person)
2007 Chandran J, Lewis P. Mad fly disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 971-2. PMID 17274117 DOI: 10.1523/Jneurosci.5427-06.2007  0.294
2017 Herranz-Martin S, Chandran J, Lewis K, Mulcahy P, Higginbottom A, Walker C, Valenzuela IMY, Jones RA, Coldicott I, Iannitti T, Akaaboune M, El-Khamisy SF, Gillingwater TH, Shaw PJ, Azzouz M. Viral delivery of C9ORF72 hexanucleotide repeat expansions in mice lead to repeat length dependent neuropathology and behavioral deficits. Disease Models & Mechanisms. PMID 28550099 DOI: 10.1242/Dmm.029892  0.292
2017 Hautbergue GM, Castelli LM, Ferraiuolo L, Sanchez-Martinez A, Cooper-Knock J, Higginbottom A, Lin YH, Bauer CS, Dodd JE, Myszczynska MA, Alam SM, Garneret P, Chandran JS, Karyka E, Stopford MJ, et al. SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits. Nature Communications. 8: 16063. PMID 28677678 DOI: 10.1038/Ncomms16063  0.273
2014 Chandran JS, Kazanis I, Clapcote SJ, Ogawa F, Millar JK, Porteous DJ, Ffrench-Constant C. Disc1 variation leads to specific alterations in adult neurogenesis. Plos One. 9: e108088. PMID 25272038 DOI: 10.1371/Journal.Pone.0108088  0.248
2021 Chowdhury EA, Meno-Tetang G, Chang HY, Wu S, Huang HW, Jamier T, Chandran J, Shah DK. Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models. Advanced Drug Delivery Reviews. PMID 33486008 DOI: 10.1016/j.addr.2021.01.017  0.161
2017 Walker C, Herranz-Martin S, Karyka E, Liao C, Lewis K, Elsayed W, Lukashchuk V, Chiang SC, Ray S, Mulcahy PJ, Jurga M, Tsagakis I, Iannitti T, Chandran J, Coldicott I, et al. C9orf72 expansion disrupts ATM-mediated chromosomal break repair. Nature Neuroscience. PMID 28714954 DOI: 10.1038/nn.4604  0.147
2017 Chandran JS, Scarrott JM, Shaw PJ, Azzouz M. Gene Therapy in the Nervous System: Failures and Successes. Advances in Experimental Medicine and Biology. 1007: 241-257. PMID 28840561 DOI: 10.1007/978-3-319-60733-7_13  0.133
2017 Chandran JS, Sharp PS, Karyka E, Aves-Cruzeiro JMDC, Coldicott I, Castelli L, Hautbergue G, Collins MO, Azzouz M. Site Specific Modification of Adeno-Associated Virus Enables Both Fluorescent Imaging of Viral Particles and Characterization of the Capsid Interactome. Scientific Reports. 7: 14766. PMID 29116194 DOI: 10.1038/s41598-017-15255-2  0.107
2022 Chandran J, Chowdhury EA, Perkinton M, Jamier T, Sutton D, Wu S, Dobson C, Shah DK, Chessell I, Meno-Tetang GML. Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes. Gene Therapy. PMID 35637286 DOI: 10.1038/s41434-022-00346-1  0.08
2023 Chowdhury EA, Ahuja M, Wu S, Liu S, Huang HW, Kumar M, Sunkara KS, Ghobrial A, Chandran J, Jamier T, Perkinton M, Meno-Tetang G, Shah DK. Pharmacokinetics of AAV9 Mediated Trastuzumab Expression in Rat Brain Following Systemic and Local Administration. Journal of Pharmaceutical Sciences. PMID 37659717 DOI: 10.1016/j.xphs.2023.08.023  0.056
2015 Chandran JS. Perspectives on disrupted-inschizophrenia 1 signaling in neurogenesis. Neural Regeneration Research. 10: 555-6. PMID 26170811 DOI: 10.4103/1673-5374.155419  0.052
Hide low-probability matches.