| Year |
Citation |
Score |
| 2022 |
Bosch DE, Jeck WR, Siderovski DP. Self-activating G protein α subunits engage seven-transmembrane Regulator of G protein Signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba Naegleria fowleri. The Journal of Biological Chemistry. 102167. PMID 35738399 DOI: 10.1016/j.jbc.2022.102167 |
0.714 |
|
| 2018 |
Ting SY, Bosch DE, Mangiameli SM, Radey MC, Huang S, Park YJ, Kelly KA, Filip SK, Goo YA, Eng JK, Allaire M, Veesler D, Wiggins PA, Peterson SB, Mougous JD. Bifunctional Immunity Proteins Protect Bacteria against FtsZ-Targeting ADP-Ribosylating Toxins. Cell. PMID 30343895 DOI: 10.1016/J.Cell.2018.09.037 |
0.32 |
|
| 2015 |
Bosch DE, Siderovski DP. Entamoeba histolytica RacC selectively engages p21-activated kinase effectors. Biochemistry. 54: 404-12. PMID 25529118 DOI: 10.1021/Bi501226F |
0.633 |
|
| 2013 |
Bosch DE, Siderovski DP. G protein signaling in the parasite Entamoeba histolytica. Experimental & Molecular Medicine. 45: e15. PMID 23519208 DOI: 10.1038/Emm.2013.30 |
0.71 |
|
| 2013 |
Bosch DE, Kimple AJ, Manning AJ, Muller RE, Willard FS, Machius M, Rogers SL, Siderovski DP. Structural determinants of RGS-RhoGEF signaling critical to Entamoeba histolytica pathogenesis. Structure (London, England : 1993). 21: 65-75. PMID 23260656 DOI: 10.1016/J.Str.2012.11.012 |
0.744 |
|
| 2013 |
Bosch DE, Siderovski DP. Structural determinants of ubiquitin conjugation in Entamoeba histolytica. The Journal of Biological Chemistry. 288: 2290-302. PMID 23209297 DOI: 10.1074/Jbc.M112.417337 |
0.583 |
|
| 2012 |
Bosch DE, Kimple AJ, Muller RE, Giguère PM, Machius M, Willard FS, Temple BR, Siderovski DP. Heterotrimeric G-protein signaling is critical to pathogenic processes in Entamoeba histolytica. Plos Pathogens. 8: e1003040. PMID 23166501 DOI: 10.1371/Journal.Ppat.1003040 |
0.72 |
|
| 2012 |
Cohen SP, Buckley BK, Kosloff M, Garland AL, Bosch DE, Cheng G, Radhakrishna H, Brown MD, Willard FS, Arshavsky VY, Tarran R, Siderovski DP, Kimple AJ. Regulator of G-protein signaling-21 (RGS21) is an inhibitor of bitter gustatory signaling found in lingual and airway epithelia. The Journal of Biological Chemistry. 287: 41706-19. PMID 23095746 DOI: 10.1074/Jbc.M112.423806 |
0.669 |
|
| 2012 |
Bosch DE, Yang B, Siderovski DP. Entamoeba histolytica Rho1 regulates actin polymerization through a divergent, diaphanous-related formin. Biochemistry. 51: 8791-801. PMID 23050667 DOI: 10.1021/Bi300954G |
0.642 |
|
| 2012 |
Bosch DE, Willard FS, Ramanujam R, Kimple AJ, Willard MD, Naqvi NI, Siderovski DP. A P-loop mutation in Gα subunits prevents transition to the active state: implications for G-protein signaling in fungal pathogenesis. Plos Pathogens. 8: e1002553. PMID 22383884 DOI: 10.1371/Journal.Ppat.1002553 |
0.723 |
|
| 2012 |
Bosch DE, Zielinski T, Lowery RG, Siderovski DP. Evaluating modulators of "Regulator of G-protein Signaling" (RGS) proteins. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit2.8. PMID 22382998 DOI: 10.1002/0471141755.Ph0208S56 |
0.71 |
|
| 2011 |
Bosch DE, Wittchen ES, Qiu C, Burridge K, Siderovski DP. Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica. The Journal of Biological Chemistry. 286: 39236-46. PMID 21930699 DOI: 10.1074/Jbc.M111.253898 |
0.648 |
|
| 2011 |
Kimple AJ, Bosch DE, Giguère PM, Siderovski DP. Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets. Pharmacological Reviews. 63: 728-49. PMID 21737532 DOI: 10.1124/Pr.110.003038 |
0.711 |
|
| 2011 |
Kosloff M, Travis AM, Bosch DE, Siderovski DP, Arshavsky VY. Integrating energy calculations with functional assays to decipher the specificity of G protein-RGS protein interactions. Nature Structural & Molecular Biology. 18: 846-53. PMID 21685921 DOI: 10.1038/Nsmb.2068 |
0.717 |
|
| 2011 |
Sammond DW, Bosch DE, Butterfoss GL, Purbeck C, Machius M, Siderovski DP, Kuhlman B. Computational design of the sequence and structure of a protein-binding peptide. Journal of the American Chemical Society. 133: 4190-2. PMID 21388199 DOI: 10.1021/Ja110296Z |
0.591 |
|
| 2011 |
Bosch DE, Kimple AJ, Sammond DW, Muller RE, Miley MJ, Machius M, Kuhlman B, Willard FS, Siderovski DP. Structural determinants of affinity enhancement between GoLoco motifs and G-protein alpha subunit mutants. The Journal of Biological Chemistry. 286: 3351-8. PMID 21115486 DOI: 10.1074/Jbc.M110.190496 |
0.692 |
|
| 2008 |
Willard FS, Zheng Z, Guo J, Digby GJ, Kimple AJ, Conley JM, Johnston CA, Bosch D, Willard MD, Watts VJ, Lambert NA, Ikeda SR, Du Q, Siderovski DP. A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics. The Journal of Biological Chemistry. 283: 36698-710. PMID 18984596 DOI: 10.1074/Jbc.M804936200 |
0.705 |
|
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