John D. Ash, Ph.D - Publications

Affiliations: 
Ophthalmology University of Florida, Gainesville, Gainesville, FL, United States 
Area:
gp130/STAT3, neuroprotection

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wang Y, Becker S, Finkelstein S, Dyka FM, Liu H, Eminhizer M, Hao Y, Brush RS, Spencer WJ, Arshavsky VY, Ash JD, Du J, Agbaga MP, Vinberg F, Ellis JM, et al. Acyl-CoA synthetase 6 controls rod photoreceptor function and survival by shaping the phospholipid composition of retinal membranes. Communications Biology. 7: 1027. PMID 39169121 DOI: 10.1038/s42003-024-06691-8  0.375
2022 Wang Y, Punzo C, Ash JD, Lobanova ES. Tsc2 knockout counteracts ubiquitin-proteasome system insufficiency and delays photoreceptor loss in retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118479119. PMID 35275792 DOI: 10.1073/pnas.2118479119  0.345
2020 Xu L, Brown EE, Santiago CP, Keuthan CJ, Lobanova E, Ash JD. Retinal homeostasis and metformin-induced protection are not affected by retina-specific Pparδ knockout. Redox Biology. 101700. PMID 32863184 DOI: 10.1016/J.Redox.2020.101700  0.52
2019 Rickman CB, Grimm C, Anderson RE, Ash JD, LaVail MM, Hollyfield JG. Correction to: Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology. 1185: C1. PMID 32274704 DOI: 10.1007/978-3-030-27378-1_95  0.436
2019 Brown EE, Lewin AS, Ash JD. AMPK May Play an Important Role in the Retinal Metabolic Ecosystem. Advances in Experimental Medicine and Biology. 1185: 477-481. PMID 31884657 DOI: 10.1007/978-3-030-27378-1_78  0.491
2019 Lobanova ES, Schuhmann K, Finkelstein S, Lewis TR, Cady MA, Hao Y, Keuthan C, Ash JD, Burns ME, Shevchenko A, Arshavsky VY. Disrupted blood-retina lysophosphatidylcholine transport impairs photoreceptor health but not visual signal transduction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31676603 DOI: 10.1523/Jneurosci.1142-19.2019  0.455
2019 Xu L, Bolch SN, Santiago CP, Dyka FM, Akil O, Lobanova ES, Wang Y, Martemyanov KA, Hauswirth WW, Smith WC, Handa JT, Blackshaw S, Ash JD, Dinculescu A. Clarin-1 expression in adult mouse and human retina highlights a role of Müller glia in Usher syndrome. The Journal of Pathology. PMID 31625146 DOI: 10.1002/Path.5360  0.458
2019 Brown EE, DeWeerd AJ, Ildefonso CJ, Lewin AS, Ash JD. Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors. Redox Biology. 24: 101201. PMID 31039480 DOI: 10.1016/J.Redox.2019.101201  0.467
2018 Xu L, Kong L, Wang J, Ash JD. Stimulation of AMPK prevents degeneration of photoreceptors and the retinal pigment epithelium. Proceedings of the National Academy of Sciences of the United States of America. PMID 30249643 DOI: 10.1073/Pnas.1802724115  0.549
2018 Santiago CP, Keuthan CJ, Boye SL, Boye SE, Imam AA, Ash JD. A Drug-Tunable Gene Therapy for Broad-Spectrum Protection against Retinal Degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30078764 DOI: 10.1016/J.Ymthe.2018.07.016  0.45
2018 Duncan JL, Pierce EA, Laster AM, Daiger SP, Birch DG, Ash JD, Iannaccone A, Flannery JG, Sahel JA, Zack DJ, Zarbin MA. Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps. Translational Vision Science & Technology. 7: 6. PMID 30034950 DOI: 10.1167/Tvst.7.4.6  0.395
2018 Hooper MJ, Wang J, Browning R, Ash JD. Damage-associated molecular pattern recognition is required for induction of retinal neuroprotective pathways in a sex-dependent manner. Scientific Reports. 8: 9115. PMID 29904087 DOI: 10.1038/S41598-018-27479-X  0.53
2018 Hooper MJ, Ash JD. Müller Cell Biological Processes Associated with Leukemia Inhibitory Factor Expression. Advances in Experimental Medicine and Biology. 1074: 479-484. PMID 29721979 DOI: 10.1007/978-3-319-75402-4_59  0.401
2016 Ildefonso CJ, Jaime H, Brown EE, Iwata RL, Ahmed CM, Massengill MT, Biswal MR, Boye SE, Hauswirth WW, Ash JD, Li Q, Lewin AS. Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide. Investigative Ophthalmology & Visual Science. 57: 372-86. PMID 26842755 DOI: 10.1167/Iovs.15-17703  0.372
2016 Xu L, Ash JD. The Role of AMPK Pathway in Neuroprotection. Advances in Experimental Medicine and Biology. 854: 425-30. PMID 26427441 DOI: 10.1007/978-3-319-17121-0_56  0.338
2016 Reagan A, Gu X, Hauck SM, Ash JD, Cao G, Thompson TC, Elliott MH. Retinal Caveolin-1 Modulates Neuroprotective Signaling. Advances in Experimental Medicine and Biology. 854: 411-8. PMID 26427439 DOI: 10.1007/978-3-319-17121-0_54  0.716
2016 Ash JD. The Potential Use of PGC-1α and PGC-1β to Protect the Retina by Stimulating Mitochondrial Repair. Advances in Experimental Medicine and Biology. 854: 403-9. PMID 26427438 DOI: 10.1007/978-3-319-17121-0_53  0.357
2014 Marchette LD, Sherry DM, Brush RS, Chan M, Wen Y, Wang J, Ash JD, Anderson RE, Mandal NA. Very long chain polyunsaturated fatty acids and rod cell structure and function. Advances in Experimental Medicine and Biology. 801: 637-45. PMID 24664753 DOI: 10.1007/978-1-4614-3209-8_80  0.387
2014 Fu S, Zhu M, Ash JD, Wang Y, Le YZ. Investigating the role of retinal Müller cells with approaches in genetics and cell biology. Advances in Experimental Medicine and Biology. 801: 401-5. PMID 24664724 DOI: 10.1007/978-1-4614-3209-8_51  0.443
2013 Hazra S, Jarajapu YP, Stepps V, Caballero S, Thinschmidt JS, Sautina L, Bengtsson N, Licalzi S, Dominguez J, Kern TS, Segal MS, Ash JD, Saban DR, Bartelmez SH, Grant MB. Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model. Diabetologia. 56: 644-53. PMID 23192694 DOI: 10.1007/S00125-012-2781-0  0.301
2012 Chollangi S, Mather T, Rodgers KK, Ash JD. A unique loop structure in oncostatin M determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor. The Journal of Biological Chemistry. 287: 32848-59. PMID 22829597 DOI: 10.1074/Jbc.M112.387324  0.309
2012 Chucair-Elliott AJ, Elliott MH, Wang J, Moiseyev GP, Ma JX, Politi LE, Rotstein NP, Akira S, Uematsu S, Ash JD. Leukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium. The Journal of Biological Chemistry. 287: 24092-102. PMID 22645143 DOI: 10.1074/Jbc.M112.378240  0.714
2012 Li X, McClellan ME, Tanito M, Garteiser P, Towner R, Bissig D, Berkowitz BA, Fliesler SJ, Woodruff ML, Fain GL, Birch DG, Khan MS, Ash JD, Elliott MH. Loss of caveolin-1 impairs retinal function due to disturbance of subretinal microenvironment. The Journal of Biological Chemistry. 287: 16424-34. PMID 22451674 DOI: 10.1074/Jbc.M112.353763  0.688
2011 Siatkowski RM, Yanovitch TL, Ash JD, Moreau A. The effects of D-penicillamine on a murine model of oxygen-induced retinopathy. Journal of Aapos : the Official Publication of the American Association For Pediatric Ophthalmology and Strabismus / American Association For Pediatric Ophthalmology and Strabismus. 15: 370-3. PMID 21907121 DOI: 10.1016/J.Jaapos.2011.04.005  0.335
2010 Zheng Y, Zhao YD, Gibbons M, Abramova T, Chu PY, Ash JD, Cunningham JM, Skapek SX. Tgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK. The Journal of Biological Chemistry. 285: 35654-64. PMID 20826783 DOI: 10.1074/Jbc.M110.128959  0.367
2010 Charles E, Joshi S, Ash JD, Fox BA, Farris AD, Bzik DJ, Lang ML, Blader IJ. CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1. Infection and Immunity. 78: 3484-92. PMID 20498261 DOI: 10.1128/Iai.00117-10  0.383
2010 Ueki Y, Chollangi S, Le YZ, Ash JD. gp130 activation in Müller cells is not essential for photoreceptor protection from light damage. Advances in Experimental Medicine and Biology. 664: 655-61. PMID 20238070 DOI: 10.1007/978-1-4419-1399-9_75  0.668
2010 Zhu M, Zheng L, Ueki Y, Ash JD, Le YZ. Unexpected transcriptional activity of the human VMD2 promoter in retinal development. Advances in Experimental Medicine and Biology. 664: 211-6. PMID 20238019 DOI: 10.1007/978-1-4419-1399-9_24  0.661
2010 Reneker LW, Bloch A, Xie L, Overbeek PA, Ash JD. Induction of corneal myofibroblasts by lens-derived transforming growth factor beta1 (TGFbeta1): a transgenic mouse model. Brain Research Bulletin. 81: 287-96. PMID 19897021 DOI: 10.1016/J.Brainresbull.2009.10.019  0.408
2009 Ueki Y, Le YZ, Chollangi S, Muller W, Ash JD. Preconditioning-induced protection of photoreceptors requires activation of the signal-transducing receptor gp130 in photoreceptors. Proceedings of the National Academy of Sciences of the United States of America. 106: 21389-94. PMID 19948961 DOI: 10.1073/Pnas.0906156106  0.674
2009 Ueki Y, Ash JD, Zhu M, Zheng L, Le YZ. Expression of Cre recombinase in retinal Müller cells. Vision Research. 49: 615-21. PMID 19948109 DOI: 10.1016/J.Visres.2009.01.012  0.658
2009 Chollangi S, Wang J, Martin A, Quinn J, Ash JD. Preconditioning-induced protection from oxidative injury is mediated by leukemia inhibitory factor receptor (LIFR) and its ligands in the retina. Neurobiology of Disease. 34: 535-44. PMID 19344761 DOI: 10.1016/J.Nbd.2009.03.012  0.464
2008 Lavail MM, Nishikawa S, Duncan JL, Yang H, Matthes MT, Yasumura D, Vollrath D, Overbeek PA, Ash JD, Robinson ML. Sustained delivery of NT-3 from lens fiber cells in transgenic mice reveals specificity of neuroprotection in retinal degenerations. The Journal of Comparative Neurology. 511: 724-35. PMID 18925574 DOI: 10.1002/Cne.21858  0.501
2008 Templeton A, Nguyen G, Ash JD, Straub RH, Carr DJ. Chemical sympathectomy increases susceptibility to ocular herpes simplex virus type 1 infection. Journal of Neuroimmunology. 197: 37-46. PMID 18495255 DOI: 10.1016/J.Jneuroim.2008.03.011  0.319
2008 Carr DJJ, Wuest T, Ash J. An increase in herpes simplex virus type 1 in the anterior segment of the eye is linked to a deficiency in NK cell infiltration in mice deficient in CXCR3 Journal of Interferon and Cytokine Research. 28: 245-251. PMID 18439102 DOI: 10.1089/Jir.2007.0110  0.374
2008 Ueki Y, Wang J, Chollangi S, Ash JD. STAT3 activation in photoreceptors by leukemia inhibitory factor is associated with protection from light damage. Journal of Neurochemistry. 105: 784-96. PMID 18088375 DOI: 10.1111/J.1471-4159.2007.05180.X  0.654
2006 Le YZ, Ash JD, Al-Ubaidi MR, Chen Y, Ma JX, Anderson RE. Conditional gene knockout system in cone photoreceptors. Advances in Experimental Medicine and Biology. 572: 173-8. PMID 17249572 DOI: 10.1007/0-387-32442-9_26  0.451
2006 Ash JD, Graham DR. Transgenic expression of leukemia inhibitory factor inhibits both rod and cone gene expression. Gp130 regulates cone gene expression. Advances in Experimental Medicine and Biology. 572: 147-53. PMID 17249568 DOI: 10.1007/0-387-32442-9_22  0.374
2006 Tomasek JJ, Haaksma CJ, Schwartz RJ, Vuong DT, Zhang SX, Ash JD, Ma JX, Al-Ubaidi MR. Deletion of smooth muscle alpha-actin alters blood-retina barrier permeability and retinal function. Investigative Ophthalmology & Visual Science. 47: 2693-700. PMID 16723488 DOI: 10.1167/Iovs.05-1297  0.411
2006 Le YZ, Zheng L, Zheng W, Ash JD, Agbaga MP, Zhu M, Anderson RE. Mouse opsin promoter-directed Cre recombinase expression in transgenic mice. Molecular Vision. 12: 389-98. PMID 16636658  0.384
2006 Carr DJ, Ash J, Lane TE, Kuziel WA. Abnormal immune response of CCR5-deficient mice to ocular infection with herpes simplex virus type 1. The Journal of General Virology. 87: 489-99. PMID 16476970 DOI: 10.1099/Vir.0.81339-0  0.358
2006 LaVail MM, Ash JD, Anderson RE, Hollyfield JG, Grimm C. Retinal degenerative diseases Advances in Experimental Medicine and Biology. 723. DOI: 10.1007/978-1-4614-0631-0  0.419
2005 Sherry DM, Mitchell R, Li H, Graham DR, Ash JD. Leukemia inhibitory factor inhibits neuronal development and disrupts synaptic organization in the mouse retina. Journal of Neuroscience Research. 82: 316-32. PMID 16206277 DOI: 10.1002/Jnr.20619  0.406
2005 Graham DR, Overbeek PA, Ash JD. Leukemia inhibitory factor blocks expression of Crx and Nrl transcription factors to inhibit photoreceptor differentiation. Investigative Ophthalmology & Visual Science. 46: 2601-10. PMID 15980254 DOI: 10.1167/Iovs.05-0129  0.485
2005 Wickham S, Lu B, Ash J, Carr DJ. Chemokine receptor deficiency is associated with increased chemokine expression in the peripheral and central nervous systems and increased resistance to herpetic encephalitis. Journal of Neuroimmunology. 162: 51-9. PMID 15833359 DOI: 10.1016/J.Jneuroim.2005.01.001  0.39
2004 Le YZ, Ash JD, Al-Ubaidi MR, Chen Y, Ma JX, Anderson RE. Targeted expression of Cre recombinase to cone photoreceptors in transgenic mice. Molecular Vision. 10: 1011-8. PMID 15635292  0.381
2004 Wickham S, Ash J, Lane TE, Carr DJ. Consequences of CXCL10 and IL-6 induction by the murine IFN-alpha1 transgene in ocular herpes simplex virus type 1 infection. Immunologic Research. 30: 191-200. PMID 15477660 DOI: 10.1385/Ir:30:2:191  0.314
2004 Huang H, Li F, Alvarez RA, Ash JD, Anderson RE. Downregulation of ATP synthase subunit-6, cytochrome c oxidase-III, and NADH dehydrogenase-3 by bright cyclic light in the rat retina. Investigative Ophthalmology & Visual Science. 45: 2489-96. PMID 15277468 DOI: 10.1167/Iovs.03-1081  0.41
2003 Rajala RV, McClellan ME, Ash JD, Anderson RE. Regulation of retinal phosphoinositide 3-kinase activity in p85alpha-subunit knockout mice. Advances in Experimental Medicine and Biology. 533: 369-76. PMID 15180287 DOI: 10.1007/978-1-4615-0067-4_47  0.313
2003 Carr DJ, Chodosh J, Ash J, Lane TE. Effect of anti-CXCL10 monoclonal antibody on herpes simplex virus type 1 keratitis and retinal infection. Journal of Virology. 77: 10037-46. PMID 12941914 DOI: 10.1128/Jvi.77.18.10037-10046.2003  0.4
2002 Jeong JH, Hines-Boykin R, Ash JD, Dittmer DP. Tissue specificity of the Kaposi's sarcoma-associated herpesvirus latent nuclear antigen (LANA/orf73) promoter in transgenic mice. Journal of Virology. 76: 11024-32. PMID 12368345 DOI: 10.1128/Jvi.76.21.11024-11032.2002  0.354
2002 Rajala RV, McClellan ME, Ash JD, Anderson RE. In vivo regulation of phosphoinositide 3-kinase in retina through light-induced tyrosine phosphorylation of the insulin receptor beta-subunit. The Journal of Biological Chemistry. 277: 43319-26. PMID 12213821 DOI: 10.1074/Jbc.M206355200  0.398
2002 Carr DJ, Ash J, Al-Khatib K, Campbell IL. Unforeseen consequences of IL-12 expression in the eye of GFAP-IL12 transgenic mice following herpes simplex virus type 1 infection. Dna and Cell Biology. 21: 467-73. PMID 12167250 DOI: 10.1089/10445490260099764  0.366
2002 Chen Q, Ash JD, Branton P, Fromm L, Overbeek PA. Inhibition of crystallin expression and induction of apoptosis by lens-specific E1A expression in transgenic mice. Oncogene. 21: 1028-37. PMID 11850820 DOI: 10.1038/Sj.Onc.1205050  0.355
2000 Vinores SA, Seo MS, Okamoto N, Ash JD, Wawrousek EF, Xiao WH, Hudish T, Derevjanik NL, Campochiaro PA. Experimental models of growth factor-mediated angiogenesis and blood-retinal barrier breakdown. General Pharmacology. 35: 233-9. PMID 11888678 DOI: 10.1016/S0306-3623(01)00117-3  0.433
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