Year |
Citation |
Score |
2019 |
Nielsen CP, Jernigan KK, Diggins NL, Webb DJ, MacGurn JA. USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification. Cell Reports. 28: 1074-1089.e5. PMID 31340145 DOI: 10.1016/J.Celrep.2019.06.083 |
0.346 |
|
2018 |
Diggins NL, Kang H, Weaver A, Webb DJ. α5β1 integrin trafficking and Rac activation are regulated by APPL1 in a Rab5-dependent manner to inhibit cell migration. Journal of Cell Science. PMID 29361527 DOI: 10.1242/Jcs.207019 |
0.501 |
|
2017 |
Erdogan B, Ao M, White LM, Means AL, Brewer BM, Yang L, Washington MK, Shi C, Franco OE, Weaver AM, Hayward SW, Li D, Webb DJ. Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin. The Journal of Cell Biology. PMID 29021221 DOI: 10.1083/Jcb.201704053 |
0.339 |
|
2017 |
Diggins NL, Webb DJ. APPL1 is a multifunctional endosomal signaling adaptor protein. Biochemical Society Transactions. 45: 771-779. PMID 28620038 DOI: 10.1042/Bst20160191 |
0.357 |
|
2017 |
Erdogan B, Webb DJ. Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis. Biochemical Society Transactions. 45: 229-236. PMID 28202677 DOI: 10.1042/Bst20160387 |
0.323 |
|
2016 |
Yang L, Carrington LJ, Erdogan B, Ao M, Brewer BM, Webb DJ, Li D. Biomechanics of Cell Reorientation in a Three-Dimensional Matrix under Compression. Experimental Cell Research. PMID 27919745 DOI: 10.1016/J.Yexcr.2016.12.002 |
0.333 |
|
2016 |
Robinson CM, Patel MR, Webb DJ. Super resolution microscopy is poised to reveal new insights into the formation and maturation of dendritic spines. F1000research. 5. PMID 27408691 DOI: 10.12688/F1000Research.8649.1 |
0.393 |
|
2015 |
Brown JA, Pensabene V, Markov DA, Allwardt V, Neely MD, Shi M, Britt CM, Hoilett OS, Yang Q, Brewer BM, Samson PC, McCawley LJ, May JM, Webb DJ, Li D, et al. Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor. Biomicrofluidics. 9: 054124. PMID 26576206 DOI: 10.1063/1.4934713 |
0.308 |
|
2015 |
Evans JC, Robinson CM, Shi M, Webb DJ. The guanine nucleotide exchange factor (GEF) Asef2 promotes dendritic spine formation via Rac activation and spinophilin-dependent targeting. The Journal of Biological Chemistry. 290: 10295-308. PMID 25750125 DOI: 10.1074/Jbc.M114.605543 |
0.445 |
|
2015 |
Ao M, Brewer BM, Yang L, Franco Coronel OE, Hayward SW, Webb DJ, Li D. Stretching fibroblasts remodels fibronectin and alters cancer cell migration. Scientific Reports. 5: 8334. PMID 25660754 DOI: 10.1038/Srep08334 |
0.361 |
|
2015 |
Broussard JA, Diggins NL, Hummel S, Georgescu W, Quaranta V, Webb DJ. Automated analysis of cell-matrix adhesions in 2D and 3D environments. Scientific Reports. 5: 8124. PMID 25630460 DOI: 10.1038/Srep08124 |
0.708 |
|
2014 |
Jean L, Yang L, Majumdar D, Gao Y, Shi M, Brewer BM, Li D, Webb DJ. The Rho family GEF Asef2 regulates cell migration in three dimensional (3D) collagen matrices through myosin II. Cell Adhesion & Migration. 8: 460-7. PMID 25517435 DOI: 10.4161/19336918.2014.983778 |
0.404 |
|
2014 |
Evans JC, Hines KM, Forsythe JG, Erdogan B, Shi M, Hill S, Rose KL, McLean JA, Webb DJ. Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. Journal of Proteome Research. 13: 3303-13. PMID 24874604 DOI: 10.1021/Pr5001384 |
0.457 |
|
2013 |
Jean L, Majumdar D, Shi M, Hinkle LE, Diggins NL, Ao M, Broussard JA, Evans JC, Choma DP, Webb DJ. Activation of Rac by Asef2 promotes myosin IIdependent contractility to inhibit cell migration on type I collagen Journal of Cell Science. 126: 5585-5597. PMID 24144700 DOI: 10.1242/Jcs.131060 |
0.757 |
|
2013 |
Lin WH, Hurley JT, Raines AN, Cheney RE, Webb DJ. Myosin X and its motorless isoform differentially modulate dendritic spine development by regulating trafficking and retention of vasodilator-stimulated phosphoprotein. Journal of Cell Science. 126: 4756-68. PMID 23943878 DOI: 10.1242/Dev.105171 |
0.747 |
|
2013 |
Shi M, Majumdar D, Gao Y, Brewer BM, Goodwin CR, McLean JA, Li D, Webb DJ. Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts. Lab On a Chip. 13: 3008-21. PMID 23736663 DOI: 10.1039/C3Lc50249J |
0.32 |
|
2013 |
Broussard JA, Rappaz B, Webb DJ, Brown CM. Fluorescence resonance energy transfer microscopy as demonstrated by measuring the activation of the serine/threonine kinase Akt. Nature Protocols. 8: 265-81. PMID 23306460 DOI: 10.1038/Nprot.2012.147 |
0.676 |
|
2012 |
Webb DJ, Brown CM, DeMali KA. Signals regulating adhesion dynamics. Journal of Signal Transduction. 2012: 785196. PMID 23346395 DOI: 10.1155/2012/785196 |
0.509 |
|
2012 |
Forsythe JG, Broussard JA, Lawrie JL, Kliman M, Jiao Y, Weiss SM, Webb DJ, McLean JA. Semitransparent nanostructured films for imaging mass spectrometry and optical microscopy. Analytical Chemistry. 84: 10665-70. PMID 23146026 DOI: 10.1021/Ac3022967 |
0.685 |
|
2012 |
Wieczorek L, Majumdar D, Wills TA, Hu L, Winder DG, Webb DJ, Muglia LJ. Absence of Ca2+-stimulated adenylyl cyclases leads to reduced synaptic plasticity and impaired experience-dependent fear memory. Translational Psychiatry. 2: e126. PMID 22832970 DOI: 10.1038/Tp.2012.50 |
0.314 |
|
2012 |
Gao Y, Sun J, Lin WH, Webb D, Li D. A compact microfluidic gradient generator using passive pumping. Microfluidics and Nanofluidics. 12: 887-895. PMID 22737106 DOI: 10.1007/S10404-011-0908-0 |
0.676 |
|
2012 |
Broussard JA, Lin WH, Majumdar D, Anderson B, Eason B, Brown CM, Webb DJ. The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration. Molecular Biology of the Cell. 23: 1486-99. PMID 22379109 DOI: 10.1091/Mbc.E11-02-0124 |
0.778 |
|
2011 |
Gao Y, Majumdar D, Jovanovic B, Shaifer C, Lin PC, Zijlstra A, Webb DJ, Li D. A versatile valve-enabled microfluidic cell co-culture platform and demonstration of its applications to neurobiology and cancer biology. Biomedical Microdevices. 13: 539-48. PMID 21424383 DOI: 10.1007/S10544-011-9523-9 |
0.39 |
|
2011 |
Majumdar D, Nebhan CA, Hu L, Anderson B, Webb DJ. An APPL1/Akt signaling complex regulates dendritic spine and synapse formation in hippocampal neurons. Molecular and Cellular Neurosciences. 46: 633-44. PMID 21236345 DOI: 10.1016/J.Mcn.2011.01.003 |
0.449 |
|
2010 |
Svitkina T, Lin WH, Webb DJ, Yasuda R, Wayman GA, Van Aelst L, Soderling SH. Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14937-42. PMID 21068295 DOI: 10.1523/Jneurosci.4276-10.2010 |
0.745 |
|
2010 |
Lin WH, Nebhan CA, Anderson BR, Webb DJ. Vasodilator-stimulated phosphoprotein (VASP) induces actin assembly in dendritic spines to promote their development and potentiate synaptic strength. The Journal of Biological Chemistry. 285: 36010-20. PMID 20826790 DOI: 10.1074/Jbc.M110.129841 |
0.75 |
|
2010 |
Gruver JS, Potdar AA, Jeon J, Sai J, Anderson B, Webb D, Richmond A, Quaranta V, Cummings PT, Chung CY. Bimodal analysis reveals a general scaling law governing nondirected and chemotactic cell motility. Biophysical Journal. 99: 367-76. PMID 20643054 DOI: 10.1016/J.Bpj.2010.03.073 |
0.35 |
|
2010 |
Gant-Branum RL, Broussard JA, Mahsut A, Webb DJ, McLean JA. Identification of phosphorylation sites within the signaling adaptor APPL1 by mass spectrometry. Journal of Proteome Research. 9: 1541-8. PMID 20095645 DOI: 10.1021/Pr901043E |
0.695 |
|
2009 |
Lin WH, Webb DJ. Actin and Actin-Binding Proteins: Masters of Dendritic Spine Formation, Morphology, and Function. The Open Neuroscience Journal. 3: 54-66. PMID 20717495 DOI: 10.2174/1874082000903020054 |
0.746 |
|
2009 |
Bristow JM, Sellers MH, Majumdar D, Anderson B, Hu L, Webb DJ. The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration. Journal of Cell Science. 122: 4535-46. PMID 19934221 DOI: 10.1242/Jcs.053728 |
0.753 |
|
2009 |
Majumdar D, Webb DJ. The role of integrins at synapses The Sticky Synapse: Cell Adhesion Molecules and Their Role in Synapse Formation and Maintenance. 385-395. DOI: 10.1007/978-0-387-92708-4_19 |
0.313 |
|
2008 |
Wegner AM, Nebhan CA, Hu L, Majumdar D, Meier KM, Weaver AM, Webb DJ. N-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses. The Journal of Biological Chemistry. 283: 15912-20. PMID 18430734 DOI: 10.1074/Jbc.M801555200 |
0.73 |
|
2008 |
Broussard JA, Webb DJ, Kaverina I. Asymmetric focal adhesion disassembly in motile cells. Current Opinion in Cell Biology. 20: 85-90. PMID 18083360 DOI: 10.1016/J.Ceb.2007.10.009 |
0.759 |
|
2007 |
Peacock JG, Miller AL, Bradley WD, Rodriguez OC, Webb DJ, Koleske AJ. The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin. Molecular Biology of the Cell. 18: 3860-72. PMID 17652459 DOI: 10.1091/Mbc.E07-01-0075 |
0.491 |
|
2007 |
Webb DJ, Zhang H, Majumdar D, Horwitz AF. alpha5 integrin signaling regulates the formation of spines and synapses in hippocampal neurons. The Journal of Biological Chemistry. 282: 6929-35. PMID 17213186 DOI: 10.1074/Jbc.M610981200 |
0.444 |
|
2006 |
Mayhew MW, Webb DJ, Kovalenko M, Whitmore L, Fox JW, Horwitz AF. Identification of protein networks associated with the PAK1-betaPIX-GIT1-paxillin signaling complex by mass spectrometry. Journal of Proteome Research. 5: 2417-23. PMID 16944954 DOI: 10.1021/Pr060140T |
0.314 |
|
2006 |
Lieu AS, Li JZ, Webb DJ, Hankins GR, Howng SL, Helm GA. Functions of G protein-coupled receptor kinase interacting protein 1 in human neuronal (NT2N) cells. Journal of Neurosurgery. 105: 103-10. PMID 16871884 DOI: 10.3171/Jns.2006.105.1.103 |
0.399 |
|
2006 |
Webb DJ, Mayhew MW, Kovalenko M, Schroeder MJ, Jeffery ED, Whitmore L, Shabanowitz J, Hunt DF, Horwitz AF. Identification of phosphorylation sites in GIT1. Journal of Cell Science. 119: 2847-50. PMID 16825424 DOI: 10.1242/Jcs03044 |
0.317 |
|
2006 |
Webb DJ, Kovalenko M, Whitmore L, Horwitz AF. Phosphorylation of serine 709 in GIT1 regulates protrusive activity in cells. Biochemical and Biophysical Research Communications. 346: 1284-8. PMID 16797488 DOI: 10.1016/J.Bbrc.2006.06.036 |
0.446 |
|
2006 |
Nayal A, Webb DJ, Brown CM, Schaefer EM, Vicente-Manzanares M, Horwitz AR. Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics. The Journal of Cell Biology. 173: 587-9. PMID 16717130 DOI: 10.1083/Jcb.200509075 |
0.473 |
|
2005 |
Vicente-Manzanares M, Webb DJ, Horwitz AR. Cell migration at a glance. Journal of Cell Science. 118: 4917-9. PMID 16254237 DOI: 10.1242/Jcs.02662 |
0.312 |
|
2005 |
Schroeder MJ, Webb DJ, Shabanowitz J, Horwitz AF, Hunt DF. Methods for the detection of paxillin post-translational modifications and interacting proteins by mass spectrometry. Journal of Proteome Research. 4: 1832-41. PMID 16212439 DOI: 10.1021/Pr0502020 |
0.334 |
|
2005 |
Bryce NS, Clark ES, Leysath JL, Currie JD, Webb DJ, Weaver AM. Cortactin promotes cell motility by enhancing lamellipodial persistence. Current Biology : Cb. 15: 1276-85. PMID 16051170 DOI: 10.1016/J.Cub.2005.06.043 |
0.451 |
|
2005 |
Zhang H, Webb DJ, Asmussen H, Niu S, Horwitz AF. A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3379-88. PMID 15800193 DOI: 10.1523/Jneurosci.3553-04.2005 |
0.462 |
|
2005 |
Lieu A, Li JZ, Webb DJ, Hankins GR, Helm GA. 649. Effects of GIT1on Human Neuronal (NT2N) Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.189 |
0.37 |
|
2004 |
Wiseman PW, Brown CM, Webb DJ, Hebert B, Johnson NL, Squier JA, Ellisman MH, Horwitz AF. Spatial mapping of integrin interactions and dynamics during cell migration by image correlation microscopy. Journal of Cell Science. 117: 5521-34. PMID 15479718 DOI: 10.1242/Jcs.01416 |
0.363 |
|
2004 |
Nayal A, Webb DJ, Horwitz AF. Talin: an emerging focal point of adhesion dynamics. Current Opinion in Cell Biology. 16: 94-8. PMID 15037311 DOI: 10.1016/J.Ceb.2003.11.007 |
0.465 |
|
2004 |
Webb DJ, Donais K, Whitmore LA, Thomas SM, Turner CE, Parsons JT, Horwitz AF. FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nature Cell Biology. 6: 154-61. PMID 14743221 DOI: 10.1038/Ncb1094 |
0.485 |
|
2003 |
Webb DJ, Brown CM, Horwitz AF. Illuminating adhesion complexes in migrating cells: moving toward a bright future. Current Opinion in Cell Biology. 15: 614-20. PMID 14519397 DOI: 10.1016/S0955-0674(03)00105-4 |
0.454 |
|
2003 |
Webb DJ, Horwitz AF. New dimensions in cell migration. Nature Cell Biology. 5: 690-2. PMID 12894172 DOI: 10.1038/Ncb0803-690 |
0.413 |
|
2003 |
Zhang H, Webb DJ, Asmussen H, Horwitz AF. Synapse formation is regulated by the signaling adaptor GIT1. The Journal of Cell Biology. 161: 131-42. PMID 12695502 DOI: 10.1083/Jcb.200211002 |
0.47 |
|
2002 |
Ma Z, Thomas KS, Webb DJ, Moravec R, Salicioni AM, Mars WM, Gonias SL. Regulation of Rac1 activation by the low density lipoprotein receptor-related protein. The Journal of Cell Biology. 159: 1061-70. PMID 12499359 DOI: 10.1083/Jcb.200207070 |
0.436 |
|
2002 |
Webb DJ, Asmussen H, Murase S, Horwitz AF. Cell migration in slice cultures. Methods in Cell Biology. 69: 341-58. PMID 12071004 DOI: 10.1016/S0091-679X(02)69022-3 |
0.422 |
|
2002 |
Webb DJ, Parsons JT, Horwitz AF. Adhesion assembly, disassembly and turnover in migrating cells - Over and over and over again Nature Cell Biology. 4: E97-E100. PMID 11944043 DOI: 10.1038/Ncb0402-E97 |
0.435 |
|
2002 |
Manabe R, Kovalenko M, Webb DJ, Horwitz AR. GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration. Journal of Cell Science. 115: 1497-510. PMID 11896197 |
0.344 |
|
2001 |
Laukaitis CM, Webb DJ, Donais K, Horwitz AF. Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells. The Journal of Cell Biology. 153: 1427-40. PMID 11425873 DOI: 10.1083/Jcb.153.7.1427 |
0.335 |
|
2001 |
Webb DJ, Thomas KS, Gonias SL. Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotes MCF-7 cell growth. The Journal of Cell Biology. 152: 741-52. PMID 11266465 DOI: 10.1083/Jcb.152.4.741 |
0.438 |
|
2000 |
Nguyen DH, Webb DJ, Catling AD, Song Q, Dhakephalkar A, Weber MJ, Ravichandran KS, Gonias SL. Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc complex is associated with the transient phosphorylation of ERK in urokinase-treated cells. The Journal of Biological Chemistry. 275: 19382-8. PMID 10777511 DOI: 10.1074/Jbc.M909575199 |
0.43 |
|
1999 |
Nguyen DH, Catling AD, Webb DJ, Sankovic M, Walker LA, Somlyo AV, Weber MJ, Gonias SL. Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner. The Journal of Cell Biology. 146: 149-64. PMID 10402467 DOI: 10.1083/Jcb.146.1.149 |
0.443 |
|
1999 |
Webb DJ, Nguyen DH, Sankovic M, Gonias SL. The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro. The Journal of Biological Chemistry. 274: 7412-20. PMID 10066806 DOI: 10.1074/Jbc.274.11.7412 |
0.384 |
|
1993 |
Anonick PK, Yoo JK, Webb DJ, Gonias SL. Characterization of the antiplasmin activity of human thrombospondin-1 in solution Biochemical Journal. 289: 903-909. PMID 7679575 DOI: 10.1042/Bj2890903 |
0.316 |
|
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