Denis C. Shields, PhD - Publications

Affiliations: 
Complex and Adaptive Systems Laboratory University College Dublin, Dublin, County Dublin, Ireland 
Area:
Genetics, Bioinformatics
Website:
http://bioinfo-casl.ucd.ie/shields

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Agoni C, Stavropoulos I, Kirwan A, Mysior MM, Holton T, Kranjc T, Simpson JC, Roche HM, Shields DC. Cell-Penetrating Milk-Derived Peptides with a Non-Inflammatory Profile. Molecules (Basel, Switzerland). 28. PMID 37836842 DOI: 10.3390/molecules28196999  0.643
2021 Mészáros B, Sámano-Sánchez H, Alvarado-Valverde J, Čalyševa J, Martínez-Pérez E, Alves R, Shields DC, Kumar M, Rippmann F, Chemes LB, Gibson TJ. Short linear motif candidates in the cell entry system used by SARS-CoV-2 and their potential therapeutic implications. Science Signaling. 14. PMID 33436497 DOI: 10.1126/scisignal.abd0334  0.569
2020 Seoighe C, Bracken AP, Buckley P, Doran P, Green R, Healy S, Kavanagh D, Kenny E, Lawler M, Lowery M, Morris D, Morrissey D, O'Byrne JJ, Shields D, Smith O, et al. The future of genomics in Ireland - focus on genomics for health. Hrb Open Research. 3: 89. PMID 33855271 DOI: 10.12688/hrbopenres.13187.1  0.522
2020 McGauran G, Dorris E, Borza R, Morgan N, Shields DC, Matallanas D, Wilson AG, O'Connell DJ. Resolving the Interactome of the Human Immune Regulator MACIR with Enhanced Membrane Protein Preparation and Affinity Proteomics. Proteomics. e2000062. PMID 32864787 DOI: 10.1002/Pmic.202000062  0.412
2020 O'Brien KT, Mooney C, Lopez C, Pollastri G, Shields DC. Prediction of polyproline II secondary structure propensity in proteins. Royal Society Open Science. 7: 191239. PMID 32218953 DOI: 10.1098/Rsos.191239  0.405
2019 Manguy J, Shields DC. Implications of kappa-casein evolutionary diversity for the self-assembly and aggregation of casein micelles. Royal Society Open Science. 6: 190939. PMID 31824707 DOI: 10.1098/Rsos.190939  0.379
2019 Davey NE, Babu MM, Blackledge M, Bridge A, Capella-Gutierrez S, Dosztanyi Z, Drysdale R, Edwards RJ, Elofsson A, Felli IC, Gibson TJ, Gutmanas A, Hancock JM, Harrow J, Higgins D, ... ... Shields DC, et al. An intrinsically disordered proteins community for ELIXIR. F1000research. 8. PMID 31824649 DOI: 10.12688/F1000Research.20136.1  0.7
2019 Duffy F, Maheshwari N, Buchete NV, Shields D. Computational Opportunities and Challenges in Finding Cyclic Peptide Modulators of Protein-Protein Interactions. Methods in Molecular Biology (Clifton, N.J.). 2001: 73-95. PMID 31134568 DOI: 10.1007/978-1-4939-9504-2_5  0.353
2019 O'Brien KT, Golla K, Kranjc T, O'Donovan D, Allen S, Maguire P, Simpson JC, O'Connell D, Moran N, Shields DC. Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome. Plos One. 14: e0210337. PMID 30689642 DOI: 10.1371/Journal.Pone.0210337  0.41
2018 Golla K, Stavropoulos I, Shields DC, Moran N. Peptides derived from cadherin juxtamembrane region inhibit platelet function. Royal Society Open Science. 5: 172347. PMID 30473799 DOI: 10.1098/Rsos.172347  0.356
2018 Krassowski T, Coughlan AY, Shen XX, Zhou X, Kominek J, Opulente DA, Riley R, Grigoriev IV, Maheshwari N, Shields DC, Kurtzman CP, Hittinger CT, Rokas A, Wolfe KH. Evolutionary instability of CUG-Leu in the genetic code of budding yeasts. Nature Communications. 9: 1887. PMID 29760453 DOI: 10.1038/S41467-018-04374-7  0.534
2018 Drummond E, Flynn S, Whelan H, Nongonierma AB, Holton TA, Robinson A, Egan T, Cagney G, Shields DC, Gibney ER, Newsholme P, Gaudel C, Jacquier JC, Noronha N, Fitzgerald RJ, et al. A casein hydrolysate with glycaemic control properties: evidence from cell, animal models and humans. Journal of Agricultural and Food Chemistry. PMID 29638124 DOI: 10.1021/Acs.Jafc.7B05550  0.64
2016 Kranjc T, Dempsey E, Cagney G, Nakamura N, Shields DC, Simpson JC. Functional characterisation of the YIPF protein family in mammalian cells. Histochemistry and Cell Biology. PMID 27999994 DOI: 10.1007/S00418-016-1527-3  0.353
2016 Manguy J, Jehl P, Dillon ET, Davey NE, Shields DC, Holton TA. Peptigram: A Web-Based Application for Peptidomics Data Visualization. Journal of Proteome Research. PMID 27997202 DOI: 10.1021/Acs.Jproteome.6B00751  0.739
2016 Jehl P, Manguy J, Shields DC, Higgins DG, Davey NE. ProViz-a web-based visualization tool to investigate the functional and evolutionary features of protein sequences. Nucleic Acids Research. PMID 27085803 DOI: 10.1093/Nar/Gkw265  0.582
2016 Holton TA, Dillon ET, Robinson A, Wynne K, Cagney G, Shields DC. Optimal computational comparison of mass spectrometric peptide profiles of alternative hydrolysates from the same starting material Lwt. 73: 296-302. DOI: 10.1016/J.Lwt.2016.06.025  0.676
2015 Olorin E, O'Brien KT, Palopoli N, Pérez-Bercoff Å, Shields DC, Edwards RJ. SLiMScape 3.x: a Cytoscape 3 app for discovery of Short Linear Motifs in protein interaction networks. F1000research. 4: 477. PMID 26674271 DOI: 10.12688/F1000Research.6773.1  0.507
2015 Bianchin A, Bell A, Chubb AJ, Doolan N, Leneghan D, Stavropoulos I, Shields DC, Mooney C. Design and evaluation of antimalarial peptides derived from prediction of short linear motifs in proteins related to erythrocyte invasion. Plos One. 10: e0127383. PMID 26039561 DOI: 10.1371/Journal.Pone.0127383  0.378
2015 Duffy FJ, O'Donovan D, Devocelle M, Moran N, O'Connell DJ, Shields DC. Virtual screening using combinatorial cyclic peptide libraries reveals protein interfaces readily targetable by cyclic peptides. Journal of Chemical Information and Modeling. 55: 600-13. PMID 25668361 DOI: 10.1021/Ci500431Q  0.419
2015 Duffy FJ, Devocelle M, Shields DC. Computational approaches to developing short cyclic peptide modulators of protein-protein interactions. Methods in Molecular Biology (Clifton, N.J.). 1268: 241-71. PMID 25555728 DOI: 10.1007/978-1-4939-2285-7_11  0.365
2014 Holton TA, Vijayakumar V, Dallas DC, Guerrero A, Borghese RA, Lebrilla CB, German JB, Barile D, Underwood MA, Shields DC, Khaldi N. Following the digestion of milk proteins from mother to baby. Journal of Proteome Research. 13: 5777-83. PMID 25385259 DOI: 10.1021/Pr5006907  0.635
2014 Duffy FJ, Devocelle M, Croucher DR, Shields DC. Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions. Bmc Bioinformatics. 15: 305. PMID 25231912 DOI: 10.1186/1471-2105-15-305  0.42
2014 Nongonierma AB, Mooney C, Shields DC, Fitzgerald RJ. In silico approaches to predict the potential of milk protein-derived peptides as dipeptidyl peptidase IV (DPP-IV) inhibitors Peptides. 57: 43-51. PMID 24793774 DOI: 10.1016/J.Peptides.2014.04.018  0.344
2014 Khaldi N, Vijayakumar V, Dallas DC, Guerrero A, Wickramasinghe S, Smilowitz JT, Medrano JF, Lebrilla CB, Shields DC, German JB. Predicting the important enzymes in human breast milk digestion. Journal of Agricultural and Food Chemistry. 62: 7225-32. PMID 24620897 DOI: 10.1021/Jf405601E  0.345
2014 Ruhanen H, Hurley D, Ghosh A, O'Brien KT, Johnston CR, Shields DC. Potential of known and short prokaryotic protein motifs as a basis for novel peptide-based antibacterial therapeutics: a computational survey. Frontiers in Microbiology. 5: 4. PMID 24478765 DOI: 10.3389/Fmicb.2014.00004  0.441
2014 Khaldi N, Holton TA, Shields DC. Amino acid enrichment and compositional changes among mammalian milk proteins and the resulting nutritional consequences. Journal of Dairy Science. 97: 1248-58. PMID 24472131 DOI: 10.3168/Jds.2013-7317  0.679
2013 Holton TA, Pollastri G, Shields DC, Mooney C. CPPpred: prediction of cell penetrating peptides. Bioinformatics (Oxford, England). 29: 3094-6. PMID 24064418 DOI: 10.1093/Bioinformatics/Btt518  0.677
2013 Khan W, Duffy F, Pollastri G, Shields DC, Mooney C. Predicting binding within disordered protein regions to structurally characterised peptide-binding domains. Plos One. 8: e72838. PMID 24019881 DOI: 10.1371/Journal.Pone.0072838  0.425
2013 O'Brien KT, Haslam NJ, Shields DC. SLiMScape: A protein short linear motif analysis plugin for Cytoscape Bmc Bioinformatics. 14. PMID 23855714 DOI: 10.1186/1471-2105-14-224  0.755
2013 Nongonierma AB, Mooney C, Shields DC, FitzGerald RJ. Inhibition of dipeptidyl peptidase IV and xanthine oxidase by amino acids and dipeptides Food Chemistry. 141: 644-653. PMID 23768405 DOI: 10.1016/J.Foodchem.2013.02.115  0.313
2013 Pushker R, Mooney C, Davey NE, Jacqué JM, Shields DC. Marked variability in the extent of protein disorder within and between viral families. Plos One. 8: e60724. PMID 23620725 DOI: 10.1371/Journal.Pone.0060724  0.536
2013 Mooney C, Cessieux A, Shields DC, Pollastri G. SCL-Epred: a generalised de novo eukaryotic protein subcellular localisation predictor. Amino Acids. 45: 291-9. PMID 23568340 DOI: 10.1007/S00726-013-1491-3  0.411
2013 Mooney C, Haslam NJ, Holton TA, Pollastri G, Shields DC. PeptideLocator: prediction of bioactive peptides in protein sequences. Bioinformatics (Oxford, England). 29: 1120-6. PMID 23505299 DOI: 10.1093/Bioinformatics/Btt103  0.786
2012 Vijayakumar V, Guerrero AN, Davey N, Lebrilla CB, Shields DC, Khaldi N. EnzymePredictor: a tool for predicting and visualizing enzymatic cleavages of digested proteins. Journal of Proteome Research. 11: 6056-65. PMID 23098558 DOI: 10.1021/Pr300721F  0.561
2012 Mooney C, Haslam NJ, Pollastri G, Shields DC. Towards the improved discovery and design of functional peptides: common features of diverse classes permit generalized prediction of bioactivity. Plos One. 7: e45012. PMID 23056189 DOI: 10.1371/Journal.Pone.0045012  0.735
2012 Haslam NJ, Shields DC. Peptide-binding domains: Are limp handshakes safest? Science Signaling. 5. PMID 23012652 DOI: 10.1126/Scisignal.2003372  0.739
2012 Davey NE, Cowan JL, Shields DC, Gibson TJ, Coldwell MJ, Edwards RJ. SLiMPrints: conservation-based discovery of functional motif fingerprints in intrinsically disordered protein regions. Nucleic Acids Research. 40: 10628-41. PMID 22977176 DOI: 10.1093/Nar/Gks854  0.745
2012 Stavropoulos I, Khaldi N, Davey NE, O'Brien K, Martin F, Shields DC. Protein disorder and short conserved motifs in disordered regions are enriched near the cytoplasmic side of single-pass transmembrane proteins. Plos One. 7: e44389. PMID 22962613 DOI: 10.1371/Journal.Pone.0044389  0.566
2012 Sudol M, Shields DC, Farooq A. Structures of YAP protein domains reveal promising targets for development of new cancer drugs. Seminars in Cell & Developmental Biology. 23: 827-33. PMID 22609812 DOI: 10.1016/J.Semcdb.2012.05.002  0.328
2012 Haslam NJ, Shields DC. Profile-based short linear protein motif discovery Bmc Bioinformatics. 13. PMID 22607209 DOI: 10.1186/1471-2105-13-104  0.756
2012 Rue-Albrecht K, Shields DC, Khaldi N. Correlation of disorder between S. cerevisiae interacting proteins Molecular Biosystems. 8: 417-425. PMID 22108582 DOI: 10.1039/C1Mb05214D  0.356
2012 Mooney C, Pollastri G, Shields DC, Haslam NJ. Prediction of short linear protein binding regions. Journal of Molecular Biology. 415: 193-204. PMID 22079048 DOI: 10.1016/J.Jmb.2011.10.025  0.778
2012 Casey JP, Magalhaes T, Conroy JM, Regan R, Shah N, Anney R, Shields DC, Abrahams BS, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, et al. A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Human Genetics. 131: 565-79. PMID 21996756 DOI: 10.1007/S00439-011-1094-6  0.313
2012 Edwards RJ, Davey NE, O'Brien K, Shields DC. Interactome-wide prediction of short, disordered protein interaction motifs in humans. Molecular Biosystems. 8: 282-95. PMID 21879107 DOI: 10.7490/F1000Research.1089989.1  0.676
2011 Montanari F, Shields DC, Khaldi N. Differences in the number of intrinsically disordered regions between yeast duplicated proteins, and their relationship with functional divergence. Plos One. 6: e24989. PMID 21949823 DOI: 10.1371/Journal.Pone.0024989  0.362
2011 Casey F, Krogan N, Shields DC, Cagney G. Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs. Bmc Systems Biology. 5: 133. PMID 21859460 DOI: 10.1186/1752-0509-5-133  0.374
2011 Khaldi N, Shields DC. Shift in the isoelectric-point of milk proteins as a consequence of adaptive divergence between the milks of mammalian species. Biology Direct. 6: 40. PMID 21801421 DOI: 10.1186/1745-6150-6-40  0.375
2011 Mooney C, Davey N, Martin AJ, Walsh I, Shields DC, Pollastri G. In silico protein motif discovery and structural analysis. Methods in Molecular Biology (Clifton, N.J.). 760: 341-53. PMID 21780007 DOI: 10.1007/978-1-61779-176-5_21  0.596
2011 Davey NE, Haslam NJ, Shields DC, Edwards RJ. SLiMSearch 2.0: biological context for short linear motifs in proteins. Nucleic Acids Research. 39: W56-60. PMID 21622654 DOI: 10.1093/Nar/Gkr402  0.802
2011 Duffy FJ, Verniere M, Devocelle M, Bernard E, Shields DC, Chubb AJ. CycloPs: Generating virtual libraries of cyclized and constrained peptides including nonnatural amino acids Journal of Chemical Information and Modeling. 51: 829-836. PMID 21434641 DOI: 10.1021/Ci100431R  0.333
2011 Alendé N, Nielsen JE, Shields DC, Khaldi N. Evolution of the isoelectric point of mammalian proteins as a consequence of indels and adaptive evolution. Proteins. 79: 1635-48. PMID 21387414 DOI: 10.1002/Prot.22990  0.378
2010 Davey NE, Edwards RJ, Shields DC. Computational identification and analysis of protein short linear motifs. Frontiers in Bioscience (Landmark Edition). 15: 801-25. PMID 20515727 DOI: 10.2741/3647  0.682
2010 Davey NE, Haslam NJ, Shields DC, Edwards RJ. SLiMFinder: a web server to find novel, significantly over-represented, short protein motifs. Nucleic Acids Research. 38: W534-9. PMID 20497999 DOI: 10.1093/Nar/Gkq440  0.794
2010 Davey NE, Edwards RJ, Shields DC. Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated proteins. Bmc Bioinformatics. 11: 14. PMID 20055997 DOI: 10.1186/1471-2105-11-14  0.672
2010 Davey NE, Haslam NJ, Shields DC, Edwards RJ. SLiMSearch: A webserver for finding novel occurrences of short linear motifs in proteins, incorporating sequence context Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6282: 50-61. DOI: 10.1007/978-3-642-16001-1_5  0.794
2009 Casey FP, Pihan E, Shields DC. Discovery of small molecule inhibitors of protein-protein interactions using combined ligand and target score normalization Journal of Chemical Information and Modeling. 49: 2708-2717. PMID 19994847 DOI: 10.1021/Ci900294X  0.379
2009 Bernard E, Parthasarathi L, Cho MK, Aylward K, Raab M, Daxecker H, O'Dushlaine CT, Shields DC, Devocelle M, Keyes T, Cosgrave L, O'Neill S, Mok KH, Moran N. Ligand switching in cell-permeable peptides: Manipulation of the α-integrin signature motif Acs Chemical Biology. 4: 457-471. PMID 19371094 DOI: 10.1021/Cb8002623  0.343
2009 Davey NE, Shields DC, Edwards RJ. Masking residues using context-specific evolutionary conservation significantly improves short linear motif discovery. Bioinformatics (Oxford, England). 25: 443-50. PMID 19136552 DOI: 10.1093/Bioinformatics/Btn664  0.689
2008 Parthasarathi L, Casey F, Stein A, Aloy P, Shields DC. Approved drug mimics of short peptide ligands from protein interaction motifs Journal of Chemical Information and Modeling. 48: 1943-1948. PMID 18826301 DOI: 10.1021/Ci800174C  0.366
2008 Casey FP, Davey NE, Baran I, Varekova RS, Shields DC. Web server to identify similarity of amino acid motifs to compounds (SAAMCO). Journal of Chemical Information and Modeling. 48: 1524-9. PMID 18570372 DOI: 10.1021/Ci8000474  0.578
2008 O'Dushlaine CT, Shields DC. Marked variation in predicted and observed variability of tandem repeat loci across the human genome Bmc Genomics. 9. PMID 18416815 DOI: 10.1186/1471-2164-9-175  0.31
2008 Edwards RJ, Davey NE, Shields DC. CompariMotif: quick and easy comparisons of sequence motifs. Bioinformatics (Oxford, England). 24: 1307-9. PMID 18375965 DOI: 10.1093/Bioinformatics/Btn105  0.66
2008 Shields DC, Johnston CR, Wallace IM, Edwards RJ. Evolution of specificity and diversity Ancestral Sequence Reconstruction. DOI: 10.1093/acprof:oso/9780199299188.003.0019  0.384
2007 Edwards RJ, Davey NE, Shields DC. SLiMFinder: a probabilistic method for identifying over-represented, convergently evolved, short linear motifs in proteins. Plos One. 2: e967. PMID 17912346 DOI: 10.1371/Journal.Pone.0000967  0.679
2007 Davey NE, Edwards RJ, Shields DC. The SLiMDisc server: short, linear motif discovery in proteins. Nucleic Acids Research. 35: W455-9. PMID 17576682 DOI: 10.1093/Nar/Gkm400  0.683
2007 Baran I, Varekova RS, Parthasarathi L, Suchomel S, Casey F, Shields DC. Identification of potential small molecule peptidomimetics similar to motifs in proteins. Journal of Chemical Information and Modeling. 47: 464-74. PMID 17309247 DOI: 10.1021/Ci600404Q  0.416
2007 Edwards RJ, Moran N, Devocelle M, Kiernan A, Meade G, Signac W, Foy M, Park SD, Dunne E, Kenny D, Shields DC. Bioinformatic discovery of novel bioactive peptides. Nature Chemical Biology. 3: 108-12. PMID 17220901 DOI: 10.1038/Nchembio854  0.536
2007 Johnston CR, O'Dushlaine C, Fitzpatrick DA, Edwards RJ, Shields DC. Evaluation of whether accelerated protein evolution in chordates has occurred before, after, or simultaneously with gene duplication. Molecular Biology and Evolution. 24: 315-23. PMID 17065596 DOI: 10.1093/Molbev/Msl162  0.524
2006 O'Dushlaine CT, Shields DC. Tools for the identification of variable and potentially variable tandem repeats. Bmc Genomics. 7: 290. PMID 17107618 DOI: 10.1186/1471-2164-7-290  0.344
2006 Parthasarathi L, Devocelle M, Søndergaard C, Baran I, O'Dushlaine CT, Davey NE, Edwards RJ, Moran N, Kenny D, Shields DC. Absolute net charge and the biological activity of oligopeptides. Journal of Chemical Information and Modeling. 46: 2183-90. PMID 16995748 DOI: 10.1021/Ci0600760  0.642
2006 Moran N, Kiernan A, Dunne E, Edwards RJ, Shields DC, Kenny D. Monitoring modulators of platelet aggregation in a microtiter plate assay. Analytical Biochemistry. 357: 77-84. PMID 16920064 DOI: 10.1016/J.Ab.2006.06.037  0.431
2006 Davey NE, Shields DC, Edwards RJ. SLiMDisc: short, linear motif discovery, correcting for common evolutionary descent. Nucleic Acids Research. 34: 3546-54. PMID 16855291 DOI: 10.1093/Nar/Gkl486  0.686
2005 Cagney G, Park S, Chung C, Tong B, O'Dushlaine C, Shields DC, Emili A. Human tissue profiling with multidimensional protein identification technology. Journal of Proteome Research. 4: 1757-67. PMID 16212430 DOI: 10.1021/Pr0500354  0.328
2005 Edwards RJ, Shields DC. BADASP: predicting functional specificity in protein families using ancestral sequences. Bioinformatics (Oxford, England). 21: 4190-1. PMID 16159912 DOI: 10.1093/Bioinformatics/Bti678  0.571
2005 O'Dushlaine CT, Edwards RJ, Park SD, Shields DC. Tandem repeat copy-number variation in protein-coding regions of human genes. Genome Biology. 6: R69. PMID 16086851 DOI: 10.1186/Gb-2005-6-8-R69  0.548
2005 Johnston CR, Shields DC. A sequence sub-sampling algorithm increases the power to detect distant homologues. Nucleic Acids Research. 33: 3772-8. PMID 16006623 DOI: 10.1093/Nar/Gki687  0.33
2004 Edwards RJ, Shields DC. GASP: Gapped Ancestral Sequence Prediction for proteins. Bmc Bioinformatics. 5: 123. PMID 15350199 DOI: 10.1186/1471-2105-5-123  0.528
2003 Shields DC. Molecular evolution of CXC chemokines and receptors. Trends in Immunology. 24: 355; author reply 35. PMID 12860523 DOI: 10.1016/S1471-4906(03)00138-8  0.34
2003 Seoighe C, Johnston CR, Shields DC. Significantly different patterns of amino acid replacement after gene duplication as compared to after speciation. Molecular Biology and Evolution. 20: 484-90. PMID 12654935 DOI: 10.1093/Molbev/Msg059  0.627
2003 Hokamp K, Shields DC, Wolfe KH, Caffrey DR. Wrapping up BLAST and other applications for use on Unix clusters. Bioinformatics (Oxford, England). 19: 441-2. PMID 12584141 DOI: 10.1093/Bioinformatics/Btg007  0.504
2002 Shields DC, O'Halloran AM. Integrating genotypic data with transcriptomic and proteomic data. Comparative and Functional Genomics. 3: 22-7. PMID 18628875 DOI: 10.1002/Cfg.135  0.329
2002 Cotter PJ, Caffrey DR, Shields DC. Improved database searches for orthologous sequences by conditioning on outgroup sequences. Bioinformatics (Oxford, England). 18: 83-91. PMID 11836215 DOI: 10.1093/Bioinformatics/18.1.83  0.349
2000 Caffrey DR, O'Neill LA, Shields DC. A method to predict residues conferring functional differences between related proteins: application to MAP kinase pathways. Protein Science : a Publication of the Protein Society. 9: 655-70. PMID 10794408 DOI: 10.1110/Ps.9.4.655  0.371
2000 Shields DC. Gene conversion among chemokine receptors Gene. 246: 239-245. PMID 10767545 DOI: 10.1016/S0378-1119(00)00072-X  0.304
1997 Wolfe KH, Shields DC. Molecular evidence for an ancient duplication of the entire yeast genome. Nature. 387: 708-13. PMID 9192896 DOI: 10.1038/42711  0.567
1997 Shields DC, Wolfe KH. Accelerated evolution of sites undergoing mRNA editing in plant mitochondria and chloroplasts. Molecular Biology and Evolution. 14: 344-9. PMID 9066800 DOI: 10.1093/Oxfordjournals.Molbev.A025768  0.535
1996 Uhlar CM, Black IL, Shields DC, Brack CM, Schreiber G, Whitehead AS. Wallaby serum amyloid A protein: cDNA cloning, sequence and evolutionary analysis Scandinavian Journal of Immunology. 43: 271-276. PMID 8602460 DOI: 10.1046/J.1365-3083.1996.D01-34.X  0.361
1992 Shields DC, Higgins DG, Sharp PM. GCWIND: a microcomputer program for identifying open reading frames according to codon positional G+C content. Computer Applications in the Biosciences : Cabios. 8: 521-3. PMID 1422886 DOI: 10.1093/Bioinformatics/8.5.521  0.631
1990 Sharp PM, Higgins DG, Shields DC, Devine KM, Hoch JA. Bacillus Subtilis Gene Sequences Genetics and Biotechnology of Bacilli. 89-98. DOI: 10.1016/B978-0-12-274162-3.50013-X  0.526
1989 Sharp PM, Shields DC, Wolfe KH, Li WH. Chromosomal location and evolutionary rate variation in enterobacterial genes. Science (New York, N.Y.). 246: 808-10. PMID 2683084 DOI: 10.1126/Science.2683084  0.637
1989 Shields DC, Sharp PM. Evidence that mutation patterns vary among Drosophila transposable elements. Journal of Molecular Biology. 207: 843-6. PMID 2547975 DOI: 10.1016/0022-2836(89)90252-0  0.534
1988 Shields DC, Sharp PM, Higgins DG, Wright F. "Silent" sites in Drosophila genes are not neutral: evidence of selection among synonymous codons. Molecular Biology and Evolution. 5: 704-16. PMID 3146682 DOI: 10.1093/Oxfordjournals.Molbev.A040525  0.606
1988 Sharp PM, Cowe E, Higgins DG, Shields DC, Wolfe KH, Wright F. Codon usage patterns in Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Drosophila melanogaster and Homo sapiens; a review of the considerable within-species diversity. Nucleic Acids Research. 16: 8207-11. PMID 3138659 DOI: 10.1093/Nar/16.17.8207  0.703
1987 Shields DC, Sharp PM. Synonymous codon usage in Bacillus subtilis reflects both translational selection and mutational biases. Nucleic Acids Research. 15: 8023-40. PMID 3118331 DOI: 10.1093/Nar/15.19.8023  0.521
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