Year |
Citation |
Score |
2020 |
Sun Q, Wang Y, Officer A, Harismendy O, Desgrosellier JS. Abstract 6024: An integrin αvβ3+ stem-like tumor cell subset promotes breast cancer progression via c-Jun/AXL signaling Cancer Research. 80: 6024-6024. DOI: 10.1158/1538-7445.Am2020-6024 |
0.458 |
|
2019 |
Sun Q, Wang Y, Desgrosellier JS. Combined Bcl-2/Src inhibition synergize to deplete stem-like breast cancer cells. Cancer Letters. PMID 31078737 DOI: 10.1016/J.Canlet.2019.05.004 |
0.384 |
|
2018 |
Sun Q, Lesperance J, Wettersten H, Luterstein E, DeRose YS, Welm A, Cheresh DA, Desgrosellier JS. Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis. The Journal of Clinical Investigation. 128: 531-544. PMID 29227280 DOI: 10.1172/Jci93707 |
0.453 |
|
2017 |
Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA. Galectin-3, a druggable vulnerability for KRAS-addicted cancers. Cancer Discovery. PMID 28893801 DOI: 10.1158/2159-8290.Cd-17-0539 |
0.408 |
|
2016 |
Sun Q, Lesperance J, Desgrosellier JS. Abstract 3321: PUMA expression targets αvβ3/Slug+ “stem-like” tumor cells to prevent breast cancer progression independent of subtype Cancer Research. 76: 3321-3321. DOI: 10.1158/1538-7445.Am2016-3321 |
0.426 |
|
2015 |
Seguin L, Desgrosellier JS, Weis SM, Cheresh DA. Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance. Trends in Cell Biology. 25: 234-40. PMID 25572304 DOI: 10.1016/J.Tcb.2014.12.006 |
0.478 |
|
2014 |
Desgrosellier JS, Lesperance J, Seguin L, Gozo M, Kato S, Franovic A, Yebra M, Shattil SJ, Cheresh DA. Integrin αvβ3 drives slug activation and stemness in the pregnant and neoplastic mammary gland. Developmental Cell. 30: 295-308. PMID 25117682 DOI: 10.1016/J.Devcel.2014.06.005 |
0.469 |
|
2014 |
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, ... ... Desgrosellier JS, et al. An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nature Cell Biology. 16: 457-68. PMID 24747441 DOI: 10.1038/Ncb2953 |
0.391 |
|
2014 |
Kato S, Seguin L, Franovic A, Kato H, Camargo M, Desgrosellier J, Anand S, Weis S, Shattil S, Cheresh DA. Abstract 4240: Targeting Galectin-3 to reverse tumor stemness and drug resistance Cancer Research. 74: 4240-4240. DOI: 10.1158/1538-7445.Am2014-4240 |
0.403 |
|
2014 |
Desgrosellier JS, Lesperance J, Seguin L, Shattil SJ, Cheresh DA. Abstract 3034: Integrin αvβ3 drives Slug activation and stemness in the pregnant and neoplastic mammary gland Cancer Research. 74: 3034-3034. DOI: 10.1158/1538-7445.Am2014-3034 |
0.425 |
|
2014 |
Seguin LJ, Kato S, Franovic A, Camargo MF, Elliott K, Yebra M, Lesperance J, Mielgo A, Desgrosellier J, Anand S, Weis S, Cheresh D. Abstract 1916: β3 integrin/KRAS/RalB complex drives tumor stemness and resistance to EGFR inhibition Cancer Research. 74: 1916-1916. DOI: 10.1158/1538-7445.Am2014-1916 |
0.422 |
|
2013 |
Desgrosellier J, Lesperance J, Seguin L, Shattil S, Cheresh D. Abstract A036: Integrin αvβ3 drives the mammary stem cell state during pregnancy Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A036 |
0.412 |
|
2013 |
Desgrosellier J, Lesperance J, Seguin L, Cheresh D. Abstract C78: Integrin αvβ3 drives stemness in the pregnant and neoplastic mammary gland Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C78 |
0.389 |
|
2012 |
Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1. Plos One. 7: e36753. PMID 22586492 DOI: 10.1371/Journal.Pone.0036753 |
0.477 |
|
2012 |
Huang M, Anand S, Murphy EA, Desgrosellier JS, Stupack DG, Shattil SJ, Schlaepfer DD, Cheresh DA. EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation. Oncogene. 31: 2783-93. PMID 21963850 DOI: 10.1038/Onc.2011.450 |
0.473 |
|
2012 |
Seguin LJ, Mielgo A, Huang M, Camargo FC, Lesperance J, Weis SM, Desgrosellier JS, Cheresh DA. Abstract LB-344: Emergence of carcinoma resistance to EGFR blockade via an integrin avb3/RalB/NFkB signaling axis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-344 |
0.433 |
|
2011 |
Shields DJ, Murphy EA, Desgrosellier JS, Mielgo A, Lau SK, Barnes LA, Lesperance J, Huang M, Schmedt C, Tarin D, Lowy AM, Cheresh DA. Oncogenic Ras/Src cooperativity in pancreatic neoplasia. Oncogene. 30: 2123-34. PMID 21242978 DOI: 10.1038/Onc.2010.589 |
0.392 |
|
2011 |
Acevedo LM, Desgrosellier J, Cheresh DA. Abstract 1474: Semaphorin 3A potentiates metastatic disease by binding to endothelial Neuropilin-1 and disrupting vascular barrier function Cancer Research. 71: 1474-1474. DOI: 10.1158/1538-7445.Am2011-1474 |
0.435 |
|
2010 |
Shields DJ, Niessen S, Murphy EA, Mielgo A, Desgrosellier JS, Lau SK, Barnes LA, Lesperance J, Bouvet M, Tarin D, Cravatt BF, Cheresh DA. RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. Proceedings of the National Academy of Sciences of the United States of America. 107: 2189-94. PMID 20080647 DOI: 10.1073/Pnas.0911646107 |
0.473 |
|
2010 |
Desgrosellier JS, Cheresh DA. Integrins in cancer: biological implications and therapeutic opportunities. Nature Reviews. Cancer. 10: 9-22. PMID 20029421 DOI: 10.1038/Nrc2748 |
0.392 |
|
2010 |
Desgrosellier JS, Seguin L, Barnes LA, Shields DJ, Huang M, Lau SK, Prevost N, Tarin D, Shattil SJ, Cheresh DA. Abstract 3841: An integrin αvβ3/c-Src oncogenic unit promotes anchorage independence and tumor progression Cancer Research. 70: 3841-3841. DOI: 10.1158/1538-7445.Am10-3841 |
0.43 |
|
2010 |
Desgrosellier JS, Cheresh DA. Erratum: Integrins in cancer: biological implications and therapeutic opportunities Nature Reviews Cancer. 10: 890-890. DOI: 10.1038/Nrc2965 |
0.341 |
|
2009 |
Desgrosellier JS, Barnes LA, Shields DJ, Huang M, Lau SK, Prévost N, Tarin D, Shattil SJ, Cheresh DA. An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nature Medicine. 15: 1163-9. PMID 19734908 DOI: 10.1038/Nm.2009 |
0.416 |
|
2006 |
Park HJ, Ward SM, Desgrosellier JS, Georgescu SP, Papageorge AG, Zhuang X, Barnett JV, Galper JB. Transforming growth factor beta regulates the expression of the M2 muscarinic receptor in atrial myocytes via an effect on RhoA and p190RhoGAP. The Journal of Biological Chemistry. 281: 19995-20002. PMID 16707504 DOI: 10.1074/Jbc.M513095200 |
0.679 |
|
2005 |
Desgrosellier JS, Mundell NA, McDonnell MA, Moses HL, Barnett JV. Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation. Developmental Biology. 280: 201-10. PMID 15766759 DOI: 10.1016/J.Ydbio.2004.12.037 |
0.646 |
|
2003 |
Barnett JV, Desgrosellier JS. Early events in valvulogenesis: a signaling perspective. Birth Defects Research. Part C, Embryo Today : Reviews. 69: 58-72. PMID 12768658 DOI: 10.1002/Bdrc.10006 |
0.596 |
|
2002 |
Ward SM, Desgrosellier JS, Zhuang X, Barnett JV, Galper JB. Transforming growth factor beta (TGFbeta ) signaling via differential activation of activin receptor-like kinases 2 and 5 during cardiac development. Role in regulating parasympathetic responsiveness. The Journal of Biological Chemistry. 277: 50183-9. PMID 12393881 DOI: 10.1074/jbc.M209668200 |
0.676 |
|
2002 |
Russo J, Barnes A, Berger K, Desgrosellier J, Henderson J, Kanters A, Merkov L. 4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cells exposed to all-trans retinal Bmc Pharmacology. 2: 4-4. PMID 11872149 DOI: 10.1186/1471-2210-2-4 |
0.346 |
|
2000 |
Lai YT, Beason KB, Brames GP, Desgrosellier JS, Cleggett MC, Shaw MV, Brown CB, Barnett JV. Activin receptor-like kinase 2 can mediate atrioventricular cushion transformation. Developmental Biology. 222: 1-11. PMID 10885742 DOI: 10.1006/Dbio.2000.9698 |
0.679 |
|
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