Ian Parker - Publications

Affiliations: 
Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Neurobiology Biology, General Biophysics, Neuroscience Biology

73/119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lock JT, Smith IF, Parker I. Spatial-temporal patterning of Ca signals by the subcellular distribution of IP and IP receptors. Seminars in Cell & Developmental Biology. PMID 30703557 DOI: 10.1016/j.semcdb.2019.01.012  0.56
2018 Shah SI, Smith M, Swaminathan D, Parker I, Ullah G, Demuro A. CellSpecks: A Software for Automated Detection and Analysis of Calcium Channels in Live Cells. Biophysical Journal. PMID 30447989 DOI: 10.1016/j.bpj.2018.10.015  0.44
2017 Parker I, Evans KT, Ellefsen K, Lawson DA, Smith IF. Lattice light sheet imaging of membrane nanotubes between human breast cancer cells in culture and in brain metastases. Scientific Reports. 7: 11029. PMID 28887508 DOI: 10.1038/s41598-017-11223-y  0.56
2016 Lock JT, Smith IF, Parker I. Comparison of Ca(2+) puffs evoked by extracellular agonists and photoreleased IP3. Cell Calcium. PMID 28108028 DOI: 10.1016/j.ceca.2016.11.006  0.56
2016 Dickinson GD, Ellefsen KL, Dawson SP, Pearson JE, Parker I. Hindered cytoplasmic diffusion of inositol trisphosphate restricts its cellular range of action. Science Signaling. 9: ra108. PMID 27919026 DOI: 10.1126/scisignal.aag1625  0.44
2016 Lock JT, Parker I, Smith IF. Communication of Ca(2+) signals via tunneling membrane nanotubes is mediated by transmission of inositol trisphosphate through gap junctions. Cell Calcium. PMID 27388952 DOI: 10.1016/j.ceca.2016.06.004  0.56
2015 Lock JT, Parker I, Smith IF. A comparison of fluorescent Ca²⁺ indicators for imaging local Ca²⁺ signals in cultured cells. Cell Calcium. 58: 638-48. PMID 26572560 DOI: 10.1016/j.ceca.2015.10.003  0.56
2015 Lock JT, Ellefsen KL, Settle B, Parker I, Smith IF. Imaging local Ca2+ signals in cultured mammalian cells. Journal of Visualized Experiments : Jove. PMID 25867132 DOI: 10.3791/52516  0.56
2014 Sanderson MJ, Smith I, Parker I, Bootman MD. Fluorescence microscopy. Cold Spring Harbor Protocols. 2014: pdb.top071795. PMID 25275114 DOI: 10.1101/pdb.top071795  0.44
2014 Smith IF, Swaminathan D, Dickinson GD, Parker I. Single-molecule tracking of inositol trisphosphate receptors reveals different motilities and distributions. Biophysical Journal. 107: 834-45. PMID 25140418 DOI: 10.1016/j.bpj.2014.05.051  0.44
2014 Ellefsen KL, Settle B, Parker I, Smith IF. An algorithm for automated detection, localization and measurement of local calcium signals from camera-based imaging. Cell Calcium. 56: 147-56. PMID 25047761 DOI: 10.1016/j.ceca.2014.06.003  0.56
2014 Wiltgen SM, Dickinson GD, Swaminathan D, Parker I. Termination of calcium puffs and coupled closings of inositol trisphosphate receptor channels. Cell Calcium. 56: 157-68. PMID 25016315 DOI: 10.1016/j.ceca.2014.06.005  0.44
2014 Greenberg ML, Weinger JG, Matheu MP, Carbajal KS, Parker I, Macklin WB, Lane TE, Cahalan MD. Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 111: E2349-55. PMID 24843159 DOI: 10.1073/pnas.1406658111  0.44
2013 Dickinson GD, Parker I. Factors determining the recruitment of inositol trisphosphate receptor channels during calcium puffs. Biophysical Journal. 105: 2474-84. PMID 24314078 DOI: 10.1016/j.bpj.2013.10.028  0.44
2013 Matheu MP, Teijaro JR, Walsh KB, Greenberg ML, Marsolais D, Parker I, Rosen H, Oldstone MB, Cahalan MD. Three phases of CD8 T cell response in the lung following H1N1 influenza infection and sphingosine 1 phosphate agonist therapy. Plos One. 8: e58033. PMID 23533579 DOI: 10.1371/journal.pone.0058033  0.44
2013 Greenberg ML, Yu Y, Leverrier S, Zhang SL, Parker I, Cahalan MD. Orai1 function is essential for T cell homing to lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 190: 3197-206. PMID 23455504 DOI: 10.4049/jimmunol.1202212  0.44
2013 Dickinson GD, Parker I. Temperature dependence of IP3-mediated local and global Ca2+ signals. Biophysical Journal. 104: 386-95. PMID 23442860 DOI: 10.1016/j.bpj.2012.12.024  0.44
2013 Siebert AP, Ma Z, Grevet JD, Demuro A, Parker I, Foskett JK. Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins. The Journal of Biological Chemistry. 288: 6140-53. PMID 23300080 DOI: 10.1074/jbc.M112.409789  0.44
2012 Dickinson GD, Swaminathan D, Parker I. The probability of triggering calcium puffs is linearly related to the number of inositol trisphosphate receptors in a cluster. Biophysical Journal. 102: 1826-36. PMID 22768938 DOI: 10.1016/j.bpj.2012.03.029  0.44
2012 Ullah G, Parker I, Mak DO, Pearson JE. Multi-scale data-driven modeling and observation of calcium puffs. Cell Calcium. 52: 152-60. PMID 22682010 DOI: 10.1016/j.ceca.2012.04.018  0.44
2012 Matheu MP, Su Y, Greenberg ML, Blanc CA, Parker I, Scott DW, Cahalan MD. Toll-like receptor 4-activated B cells out-compete Toll-like receptor 9-activated B cells to establish peripheral immunological tolerance. Proceedings of the National Academy of Sciences of the United States of America. 109: E1258-66. PMID 22511718 DOI: 10.1073/pnas.1205150109  0.44
2011 Thurley K, Smith IF, Tovey SC, Taylor CW, Parker I, Falcke M. Timescales of IP(3)-evoked Ca(2+) spikes emerge from Ca(2+) puffs only at the cellular level. Biophysical Journal. 101: 2638-44. PMID 22261051 DOI: 10.1016/j.bpj.2011.10.030  0.44
2011 Demuro A, Smith M, Parker I. Single-channel Ca2+ imaging implicates Aβ 1-42 amyloid pores in Alzheimer's disease pathology Journal of Cell Biology. 195: 515-524. PMID 22024165 DOI: 10.1083/jcb.201104133  0.44
2011 Demuro A, Penna A, Safrina O, Yeromin AV, Amcheslavsky A, Cahalan MD, Parker I. Subunit stoichiometry of human Orai1 and Orai3 channels in closed and open states. Proceedings of the National Academy of Sciences of the United States of America. 108: 17832-7. PMID 21987805 DOI: 10.1073/pnas.1114814108  0.44
2011 Smith IF, Shuai J, Parker I. Active generation and propagation of Ca2+ signals within tunneling membrane nanotubes. Biophysical Journal. 100: L37-9. PMID 21504718 DOI: 10.1016/j.bpj.2011.03.007  0.44
2011 Matheu MP, Cahalan MD, Parker I. Immunoimaging: studying immune system dynamics using two-photon microscopy. Cold Spring Harbor Protocols. 2011: pdb.top99. PMID 21285279 DOI: 10.1101/pdb.top99  0.44
2011 Matheu MP, Cahalan MD, Parker I. In vivo lymph node imaging. Cold Spring Harbor Protocols. 2011: pdb.prot5568. PMID 21285268 DOI: 10.1101/pdb.prot5568  0.44
2011 Matheu MP, Cahalan MD, Parker I. In situ lymph node imaging. Cold Spring Harbor Protocols. 2011: pdb.prot5567. PMID 21285267 DOI: 10.1101/pdb.prot5567  0.44
2011 Matheu MP, Cahalan MD, Parker I. Induction of an immune response for imaging antigen-presenting cell/T-cell interactions. Cold Spring Harbor Protocols. 2011: pdb.prot5566. PMID 21285266 DOI: 10.1101/pdb.prot5566  0.44
2011 Matheu MP, Cahalan MD, Parker I. General approach to adoptive transfer and cell labeling for immunoimaging. Cold Spring Harbor Protocols. 2011: pdb.prot5565. PMID 21285265 DOI: 10.1101/pdb.prot5565  0.44
2010 Parker I, Smith IF. Recording single-channel activity of inositol trisphosphate receptors in intact cells with a microscope, not a patch clamp. The Journal of General Physiology. 136: 119-27. PMID 20660654 DOI: 10.1085/jgp.200910390  0.56
2010 Cárdenas C, Miller RA, Smith I, Bui T, Molgó J, Müller M, Vais H, Cheung KH, Yang J, Parker I, Thompson CB, Birnbaum MJ, Hallows KR, Foskett JK. Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. Cell. 142: 270-83. PMID 20655468 DOI: 10.1016/j.cell.2010.06.007  0.44
2010 Wiltgen SM, Smith IF, Parker I. Superresolution localization of single functional IP3R channels utilizing Ca2+ flux as a readout. Biophysical Journal. 99: 437-46. PMID 20643061 DOI: 10.1016/j.bpj.2010.04.037  0.56
2010 Reissner KJ, Pu L, Schaffhausen JH, Boyle HD, Smith IF, Parker I, Carew TJ. A novel postsynaptic mechanism for heterosynaptic sharing of short-term plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8797-806. PMID 20592201 DOI: 10.1523/JNEUROSCI.4767-09.2010  0.44
2010 Sen D, Forrest L, Kepler TB, Parker I, Cahalan MD. Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1- and Th2-polarizing adjuvants. Proceedings of the National Academy of Sciences of the United States of America. 107: 8334-9. PMID 20404167 DOI: 10.1073/pnas.0912817107  0.44
2010 Demuro A, Parker I, Stutzmann GE. Calcium signaling and amyloid toxicity in Alzheimer disease. The Journal of Biological Chemistry. 285: 12463-8. PMID 20212036 DOI: 10.1074/jbc.R109.080895  0.44
2010 Garrod KR, Liu FC, Forrest LE, Parker I, Kang SM, Cahalan MD. NK cell patrolling and elimination of donor-derived dendritic cells favor indirect alloreactivity. Journal of Immunology (Baltimore, Md. : 1950). 184: 2329-36. PMID 20139277 DOI: 10.4049/jimmunol.0902748  0.44
2010 Khoury MK, Parker I, Aswad DW. Acquisition of chemiluminescent signals from immunoblots with a digital single-lens reflex camera. Analytical Biochemistry. 397: 129-31. PMID 19788886 DOI: 10.1016/j.ab.2009.09.041  0.44
2009 Smith IF, Wiltgen SM, Shuai J, Parker I. Ca(2+) puffs originate from preestablished stable clusters of inositol trisphosphate receptors. Science Signaling. 2: ra77. PMID 19934435 DOI: 10.1126/scisignal.2000466  0.44
2009 Smith IF, Parker I. Imaging the quantal substructure of single IP3R channel activity during Ca2+ puffs in intact mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 6404-9. PMID 19332787 DOI: 10.1073/pnas.0810799106  0.56
2009 Smith IF, Wiltgen SM, Parker I. Localization of puff sites adjacent to the plasma membrane: functional and spatial characterization of Ca2+ signaling in SH-SY5Y cells utilizing membrane-permeant caged IP3. Cell Calcium. 45: 65-76. PMID 18639334 DOI: 10.1016/j.ceca.2008.06.001  0.56
2008 Matheu MP, Sen D, Cahalan MD, Parker I. Generation of bone marrow derived murine dendritic cells for use in 2-photon imaging. Journal of Visualized Experiments : Jove. PMID 19066518 DOI: 10.3791/773  0.44
2008 Matheu MP, Beeton C, Parker I, Chandy KG, D Cahalan M. Imaging effector memory T cells in the ear after induction of adoptive DTH. Journal of Visualized Experiments : Jove. PMID 19066497 DOI: 10.3791/907  0.44
2008 Matheu MP, Beeton C, Garcia A, Chi V, Rangaraju S, Safrina O, Monaghan K, Uemura MI, Li D, Pal S, de la Maza LM, Monuki E, Flügel A, Pennington MW, Parker I, et al. Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block. Immunity. 29: 602-14. PMID 18835197 DOI: 10.1016/j.immuni.2008.07.015  0.44
2008 Sen D, Deerinck TJ, Ellisman MH, Parker I, Cahalan MD. Quantum dots for tracking dendritic cells and priming an immune response in vitro and in vivo. Plos One. 3: e3290. PMID 18820727 DOI: 10.1371/journal.pone.0003290  0.44
2008 Penna A, Demuro A, Yeromin AV, Zhang SL, Safrina O, Parker I, Cahalan MD. The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Nature. 456: 116-20. PMID 18820677 DOI: 10.1038/nature07338  0.44
2008 Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. The Journal of General Physiology. 132: i1. PMID 18663130 DOI: 10.1085/JGP1322OIA1  0.56
2008 Green KN, Demuro A, Akbari Y, Hitt BD, Smith IF, Parker I, LaFerla FM. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. The Journal of Cell Biology. 181: 1107-16. PMID 18591429 DOI: 10.1083/jcb.200706171  0.44
2007 Matheu MP, Parker I, Cahalan MD. Dissection and 2-photon imaging of peripheral lymph nodes in mice. Journal of Visualized Experiments : Jove. 265. PMID 18989436 DOI: 10.3791/265  0.44
2007 Ionescu L, White C, Cheung KH, Shuai J, Parker I, Pearson JE, Foskett JK, Mak DO. Mode switching is the major mechanism of ligand regulation of InsP3 receptor calcium release channels. The Journal of General Physiology. 130: 631-45. PMID 17998395 DOI: 10.1085/jgp.200709859  0.44
2007 Matheu MP, Deane JA, Parker I, Fruman DA, Cahalan MD. Class IA phosphoinositide 3-kinase modulates basal lymphocyte motility in the lymph node. Journal of Immunology (Baltimore, Md. : 1950). 179: 2261-9. PMID 17675487  0.44
2007 Wei SH, Safrina O, Yu Y, Garrod KR, Cahalan MD, Parker I. Ca2+ signals in CD4+ T cells during early contacts with antigen-bearing dendritic cells in lymph node. Journal of Immunology (Baltimore, Md. : 1950). 179: 1586-94. PMID 17641025  0.44
2007 Garrod KR, Wei SH, Parker I, Cahalan MD. Natural killer cells actively patrol peripheral lymph nodes forming stable conjugates to eliminate MHC-mismatched targets. Proceedings of the National Academy of Sciences of the United States of America. 104: 12081-6. PMID 17609379 DOI: 10.1073/pnas.0702867104  0.44
2007 Shuai J, Pearson JE, Foskett JK, Mak DO, Parker I. A kinetic model of single and clustered IP3 receptors in the absence of Ca2+ feedback. Biophysical Journal. 93: 1151-62. PMID 17526578 DOI: 10.1529/biophysj.107.108795  0.44
2007 Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, Laferla F. Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models. Annals of the New York Academy of Sciences. 1097: 265-77. PMID 17413028 DOI: 10.1196/annals.1379.025  0.44
2006 Shuai J, Rose HJ, Parker I. The number and spatial distribution of IP3 receptors underlying calcium puffs in Xenopus oocytes. Biophysical Journal. 91: 4033-44. PMID 16980372 DOI: 10.1529/biophysj.106.088880  0.44
2006 Rose HJ, Dargan S, Shuai J, Parker I. 'Trigger' events precede calcium puffs in Xenopus oocytes. Biophysical Journal. 91: 4024-32. PMID 16980363 DOI: 10.1529/biophysj.106.088872  0.44
2006 Sanna MG, Wang SK, Gonzalez-Cabrera PJ, Don A, Marsolais D, Matheu MP, Wei SH, Parker I, Jo E, Cheng WC, Cahalan MD, Wong CH, Rosen H. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nature Chemical Biology. 2: 434-41. PMID 16829954 DOI: 10.1038/nchembio804  0.44
2006 Stutzmann GE, Smith I, Caccamo A, Oddo S, Laferla FM, Parker I. Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5180-9. PMID 16687509 DOI: 10.1523/JNEUROSCI.0739-06.2006  0.44
2005 Wei SH, Rosen H, Matheu MP, Sanna MG, Wang SK, Jo E, Wong CH, Parker I, Cahalan MD. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nature Immunology. 6: 1228-35. PMID 16273098 DOI: 10.1038/ni1269  0.44
2005 Zinselmeyer BH, Dempster J, Gurney AM, Wokosin D, Miller M, Ho H, Millington OR, Smith KM, Rush CM, Parker I, Cahalan M, Brewer JM, Garside P. In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance Journal of Experimental Medicine. 201: 1815-1823. PMID 15928201 DOI: 10.1084/jem.20050203  0.44
2005 Okada T, Miller MJ, Parker I, Krummel MF, Neighbors M, Hartley SB, O'Garra A, Cahalan MD, Cyster JG. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. Plos Biology. 3: e150. PMID 15857154 DOI: 10.1371/journal.pbio.0030150  0.44
2005 Shuai J, Parker I. Optical single-channel recording by imaging Ca2+ flux through individual ion channels: theoretical considerations and limits to resolution. Cell Calcium. 37: 283-99. PMID 15755490 DOI: 10.1016/j.ceca.2004.10.008  0.44
2005 Demuro A, Mina E, Kayed R, Milton SC, Parker I, Glabe CG. Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. The Journal of Biological Chemistry. 280: 17294-300. PMID 15722360 DOI: 10.1074/jbc.M500997200  0.44
2005 Stutzmann GE, Parker I. Dynamic multiphoton imaging: a live view from cells to systems. Physiology (Bethesda, Md.). 20: 15-21. PMID 15653835 DOI: 10.1152/physiol.00028.2004  0.44
2004 Thorn P, Fogarty KE, Parker I. Zymogen granule exocytosis is characterized by long fusion pore openings and preservation of vesicle lipid identity. Proceedings of the National Academy of Sciences of the United States of America. 101: 6774-9. PMID 15090649 DOI: 10.1073/pnas.0400336101  0.44
2004 Dargan SL, Schwaller B, Parker I. Spatiotemporal patterning of IP3-mediated Ca2+ signals in Xenopus oocytes by Ca2+-binding proteins. The Journal of Physiology. 556: 447-61. PMID 14755000 DOI: 10.1113/jphysiol.2003.059204  0.44
2004 Stutzmann GE, Caccamo A, LaFerla FM, Parker I. Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 508-13. PMID 14724250 DOI: 10.1523/JNEUROSCI.4386-03.2004  0.44
2004 Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proceedings of the National Academy of Sciences of the United States of America. 101: 998-1003. PMID 14722354 DOI: 10.1073/pnas.0306407101  0.44
2003 Wei SH, Parker I, Miller MJ, Cahalan MD. A stochastic view of lymphocyte motility and trafficking within the lymph node. Immunological Reviews. 195: 136-59. PMID 12969316 DOI: 10.1034/j.1600-065X.2003.00076.x  0.44
2003 Cahalan MD, Parker I, Wei SH, Miller MJ. Real-time imaging of lymphocytes in vivo. Current Opinion in Immunology. 15: 372-7. PMID 12900266 DOI: 10.1016/S0952-7915(03)00079-7  0.44
2003 Sanderson MJ, Parker I. Video-rate confocal microscopy. Methods in Enzymology. 360: 447-81. PMID 12622163 DOI: 10.1016/S0076-6879(03)60123-0  0.44
2003 Miller MJ, Wei SH, Cahalan MD, Parker I. Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy. Proceedings of the National Academy of Sciences of the United States of America. 100: 2604-9. PMID 12601158 DOI: 10.1073/pnas.2628040100  0.44
Low-probability matches
2008 Shuai J, Pearson JE, Parker I. Modeling Ca2+ feedback on a single inositol 1,4,5-trisphosphate receptor and its modulation by Ca2+ buffers. Biophysical Journal. 95: 3738-52. PMID 18641077 DOI: 10.1529/biophysj.108.137182  0.2
2018 Lock JT, Alzayady KJ, Yule DI, Parker I. All three IP receptor isoforms generate Ca puffs that display similar characteristics. Science Signaling. 11. PMID 30563861 DOI: 10.1126/scisignal.aau0344  0.08
2018 Ellefsen KL, Lock JT, Settle B, Karsten CA, Parker I. Applications of FLIKA, a Python-based image processing and analysis platform, for studying local events of cellular calcium signaling. Biochimica Et Biophysica Acta. Molecular Cell Research. PMID 30500432 DOI: 10.1016/j.bbamcr.2018.11.012  0.08
2018 Ellefsen KL, Parker I. Dynamic Caimaging with a simplified lattice light-sheet microscope: A sideways view of subcellular Capuffs. Cell Calcium. 71: 34-44. PMID 29604962 DOI: 10.1016/j.ceca.2017.11.005  0.08
2015 Ellefsen KL, Dynes JL, Parker I. Spinning-Spot Shadowless TIRF Microscopy. Plos One. 10: e0136055. PMID 26308212 DOI: 10.1371/journal.pone.0136055  0.08
2018 Parker IG, Hartel G, Paratz J, Choy NL, Rahmann A. A Systematic Review of the Reported Proportions of Diagnoses for Dizziness and Vertigo. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. PMID 30439765 DOI: 10.1097/MAO.0000000000002044  0.01
2018 Shah SI, Demuro A, Mak DD, Parker I, Pearson JE, Ullah G. TraceSpecks: A Software for Automated Idealization of Noisy Patch-Clamp and Imaging Data. Biophysical Journal. 115: 9-21. PMID 29972815 DOI: 10.1016/j.bpj.2018.06.003  0.01
2018 Ma Z, Taruno A, Ohmoto M, Jyotaki M, Lim JC, Miyazaki H, Niisato N, Marunaka Y, Lee RJ, Hoff H, Payne R, Demuro A, Parker I, Mitchell CH, Henao-Mejia J, et al. CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes. Neuron. PMID 29681531 DOI: 10.1016/j.neuron.2018.03.043  0.01
2017 Dong TX, Othy S, Jairaman A, Skupsky J, Zavala A, Parker I, Dynes JL, Cahalan MD. T cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse. Elife. 6. PMID 29239725 DOI: 10.7554/eLife.32417  0.01
2017 Dong TX, Othy S, Greenberg ML, Jairaman A, Akunwafo C, Leverrier S, Yu Y, Parker I, Dynes JL, Cahalan MD. Intermittent Ca2+ signals mediated by Orai1 regulate basal T cell motility. Elife. 6. PMID 29239723 DOI: 10.7554/eLife.27827  0.01
2017 Schmunk G, Nguyen RL, Ferguson DL, Kumar K, Parker I, Gargus JJ. High-throughput screen detects calcium signaling dysfunction in typical sporadic autism spectrum disorder. Scientific Reports. 7: 40740. PMID 28145469 DOI: 10.1038/srep40740  0.01
2015 Ullah G, Demuro A, Parker I, Pearson JE. Analyzing and Modeling the Kinetics of Amyloid Beta Pores Associated with Alzheimer's Disease Pathology. Plos One. 10: e0137357. PMID 26348728 DOI: 10.1371/journal.pone.0137357  0.01
2015 Demuro A, Parker I. Picomolar sensitivity to inositol trisphosphate in Xenopus oocytes. Cell Calcium. 58: 511-7. PMID 26344104 DOI: 10.1016/j.ceca.2015.08.003  0.01
2015 Weinger JG, Greenberg ML, Matheu MP, Parker I, Walsh CM, Lane TE, Cahalan MD. Two-photon imaging of cellular dynamics in the mouse spinal cord. Journal of Visualized Experiments : Jove. PMID 25742043 DOI: 10.3791/52580  0.01
2015 Matheu MP, Othy S, Greenberg ML, Dong TX, Schuijs M, Deswarte K, Hammad H, Lambrecht BN, Parker I, Cahalan MD. Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming. Nature Communications. 6: 6219. PMID 25653051 DOI: 10.1038/ncomms7219  0.01
2015 Amcheslavsky A, Wood ML, Yeromin AV, Parker I, Freites JA, Tobias DJ, Cahalan MD. Molecular biophysics of Orai store-operated Ca2+ channels. Biophysical Journal. 108: 237-46. PMID 25606672 DOI: 10.1016/j.bpj.2014.11.3473  0.01
2015 Rückl M, Parker I, Marchant JS, Nagaiah C, Johenning FW, Rüdiger S. Modulation of elementary calcium release mediates a transition from puffs to waves in an IP3R cluster model. Plos Computational Biology. 11: e1003965. PMID 25569772 DOI: 10.1371/journal.pcbi.1003965  0.01
2013 Demuro A, Parker I. Cytotoxicity of intracellular aβ42 amyloid oligomers involves Ca2+ release from the endoplasmic reticulum by stimulated production of inositol trisphosphate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3824-33. PMID 23447594 DOI: 10.1523/JNEUROSCI.4367-12.2013  0.01
2013 Yamasaki-Mann M, Demuro A, Parker I. Cytosolic [Ca2+] regulation of InsP3-evoked puffs. The Biochemical Journal. 449: 167-73. PMID 23035871 DOI: 10.1042/BJ20121271  0.01
2012 Parker I. Discursive social psychology now. The British Journal of Social Psychology / the British Psychological Society. 51: 471-7. PMID 21790666 DOI: 10.1111/j.2044-8309.2011.02046.x  0.01
2011 Yamasaki-Mann M, Parker I. Enhanced ER Ca2+ store filling by overexpression of SERCA2b promotes IP3-evoked puffs. Cell Calcium. 50: 36-41. PMID 21616533 DOI: 10.1016/j.ceca.2011.04.008  0.01
2010 Yamasaki-Mann M, Demuro A, Parker I. Modulation of endoplasmic reticulum Ca2+ store filling by cyclic ADP-ribose promotes inositol trisphosphate (IP3)-evoked Ca2+ signals. The Journal of Biological Chemistry. 285: 25053-61. PMID 20538594 DOI: 10.1074/jbc.M109.095257  0.01
2009 Zinselmeyer BH, Dempster J, Wokosin DL, Cannon JJ, Pless R, Parker I, Miller MJ. Chapter 16. Two-photon microscopy and multidimensional analysis of cell dynamics. Methods in Enzymology. 461: 349-78. PMID 19480927 DOI: 10.1016/S0076-6879(09)05416-0  0.01
2009 Yamasaki-Mann M, Demuro A, Parker I. cADPR stimulates SERCA activity in Xenopus oocytes. Cell Calcium. 45: 293-9. PMID 19131109 DOI: 10.1016/j.ceca.2008.11.008  0.01
2008 Cahalan MD, Parker I. Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annual Review of Immunology. 26: 585-626. PMID 18173372 DOI: 10.1146/annurev.immunol.24.021605.090620  0.01
2008 Demuro A, Parker I. Multi-dimensional resolution of elementary Ca2+ signals by simultaneous multi-focal imaging. Cell Calcium. 43: 367-74. PMID 17716727 DOI: 10.1016/j.ceca.2007.07.002  0.01
2007 Parker I. Swingers: bonobos are celebrated as peace-loving, matriarchal, and sexually liberated. Are they? New Yorker (New York, N.Y. : 1925). 48-61. PMID 17650578  0.01
2007 Mosig RA, Dowling O, DiFeo A, Ramirez MC, Parker IC, Abe E, Diouri J, Aqeel AA, Wylie JD, Oblander SA, Madri J, Bianco P, Apte SS, Zaidi M, Doty SB, et al. Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth. Human Molecular Genetics. 16: 1113-23. PMID 17400654 DOI: 10.1093/hmg/ddm060  0.01
2007 Parker I. Psychoanalytic cyberspace, beyond psychology. Psychoanalytic Review. 94: 63-82. PMID 17367277 DOI: 10.1521/prev.2007.94.1.63  0.01
2006 Demuro A, Parker I. Imaging single-channel calcium microdomains. Cell Calcium. 40: 413-22. PMID 17067668 DOI: 10.1016/j.ceca.2006.08.006  0.01
2006 Cahalan MD, Parker I. Imaging the choreography of lymphocyte trafficking and the immune response. Current Opinion in Immunology. 18: 476-82. PMID 16765574 DOI: 10.1016/j.coi.2006.05.013  0.01
2006 Dargan SL, Demuro A, Parker I. Imaging Ca2+ signals in Xenopus oocytes. Methods in Molecular Biology (Clifton, N.J.). 322: 103-19. PMID 16739719 DOI: 10.1007/978-1-59745-000-3_8  0.01
2006 Parker I. Plasmalemmal Ca2+ signaling in arterial smooth muscle: it's elementary! The Journal of General Physiology. 127: 605-9. PMID 16702356 DOI: 10.1085/jgp.200609567  0.01
2006 Fraiman D, Pando B, Dargan S, Parker I, Dawson SP. Analysis of puff dynamics in oocytes: interdependence of puff amplitude and interpuff interval. Biophysical Journal. 90: 3897-907. PMID 16533853 DOI: 10.1529/biophysj.105.075911  0.01
2005 Cahalan MD, Parker I. Close encounters of the first and second kind: T-DC and T-B interactions in the lymph node. Seminars in Immunology. 17: 442-51. PMID 16263308 DOI: 10.1016/j.smim.2005.09.001  0.01
2005 Demuro A, Parker I. "Optical patch-clamping": single-channel recording by imaging Ca2+ flux through individual muscle acetylcholine receptor channels. The Journal of General Physiology. 126: 179-92. PMID 16103278 DOI: 10.1085/jgp.200509331  0.01
2005 Demuro A, Parker I. Optical single-channel recording: imaging Ca2+ flux through individual ion channels with high temporal and spatial resolution. Journal of Biomedical Optics. 10: 11002. PMID 15847568 DOI: 10.1117/1.1846074  0.01
2005 Ventura AC, Bruno L, Demuro A, Parker I, Dawson SP. A model-independent algorithm to derive Ca2+ fluxes underlying local cytosolic Ca2+ transients. Biophysical Journal. 88: 2403-21. PMID 15681645 DOI: 10.1529/biophysj.104.045260  0.01
2005 Thorn P, Parker I. Two phases of zymogen granule lifetime in mouse pancreas: ghost granules linger after exocytosis of contents. The Journal of Physiology. 563: 433-42. PMID 15637100 DOI: 10.1113/jphysiol.2004.077230  0.01
2004 Demuro A, Parker I. Imaging single-channel calcium microdomains by total internal reflection microscopy. Biological Research. 37: 675-9. PMID 15709697  0.01
2004 Miller MJ, Safrina O, Parker I, Cahalan MD. Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. The Journal of Experimental Medicine. 200: 847-56. PMID 15466619 DOI: 10.1084/jem.20041236  0.01
2004 Demuro A, Parker I. Imaging the activity and localization of single voltage-gated Ca(2+) channels by total internal reflection fluorescence microscopy. Biophysical Journal. 86: 3250-9. PMID 15111438 DOI: 10.1016/S0006-3495(04)74373-8  0.01
2004 Serracino-Inglott F, Atkinson HD, Jha P, Parker I, Anderson DN. Early experiences with computed axial tomography colonography. American Journal of Surgery. 187: 511-4. PMID 15041501 DOI: 10.1016/j.amjsurg.2003.12.029  0.01
2003 Demuro A, Parker I. Optical single-channel recording: imaging Ca2+ flux through individual N-type voltage-gated channels expressed in Xenopus oocytes. Cell Calcium. 34: 499-509. PMID 14572808  0.01
2003 Dargan SL, Parker I. Buffer kinetics shape the spatiotemporal patterns of IP3-evoked Ca2+ signals. The Journal of Physiology. 553: 775-88. PMID 14555715 DOI: 10.1113/jphysiol.2003.054247  0.01
2003 Parker I. Photonics for biologists. Methods in Enzymology. 360: 345-82. PMID 12622159  0.01
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