| Year |
Citation |
Score |
| 2018 |
Gruber E, Heyward C, Cameron J, Leifer C. Toll-like receptor signaling in macrophages is regulated by extracellular substrate stiffness and Rho-associated coiled-coil kinase (ROCK1/2). International Immunology. 30: 267-278. PMID 29800294 DOI: 10.1093/Intimm/Dxy027 |
0.465 |
|
| 2016 |
Sinha SS, Cameron J, Brooks JC, Leifer CA. Complex Negative Regulation of TLR9 by Multiple Proteolytic Cleavage Events. Journal of Immunology (Baltimore, Md. : 1950). PMID 27421483 DOI: 10.4049/jimmunol.1502357 |
0.385 |
|
| 2016 |
Hasan M, Gruber E, Cameron J, Leifer CA. TLR9 stability and signaling are regulated by phosphorylation and cell stress. Journal of Leukocyte Biology. PMID 26957214 DOI: 10.1189/jlb.2A0815-337R |
0.334 |
|
| 2015 |
Patel HJ, Patel PD, Ochiana SO, Yan P, Sun W, Patel MR, Shah SK, Tramentozzi E, Brooks J, Bolaender A, Shrestha L, Stephani R, Finotti P, Leifer C, Li Z, et al. Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94. Journal of Medicinal Chemistry. 58: 3922-43. PMID 25901531 DOI: 10.1021/Acs.Jmedchem.5B00197 |
0.317 |
|
| 2014 |
Rosenthal JA, Huang CJ, Doody AM, Leung T, Mineta K, Feng DD, Wayne EC, Nishimura N, Leifer C, DeLisa MP, Mendez S, Putnam D. Mechanistic insight into the TH1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles. Plos One. 9: e112802. PMID 25426709 DOI: 10.1371/Journal.Pone.0112802 |
0.31 |
|
| 2014 |
Leifer CA, McConkey C, Li S, Chassaing B, Gewirtz AT, Ley RE. Linking genetic variation in human Toll-like receptor 5 genes to the gut microbiome's potential to cause inflammation. Immunology Letters. 162: 3-9. PMID 25284610 DOI: 10.1016/J.Imlet.2014.07.017 |
0.306 |
|
| 2013 |
Singh A, Rahman T, Malik M, Hickey AJ, Leifer CA, Hazlett KR, Sellati TJ. Discordant results obtained with Francisella tularensis during in vitro and in vivo immunological studies are attributable to compromised bacterial structural integrity. Plos One. 8: e58513. PMID 23554897 DOI: 10.1371/journal.pone.0058513 |
0.334 |
|
| 2013 |
Scalfone LK, Nel HJ, Gagliardo LF, Cameron JL, Al-Shokri S, Leifer CA, Fallon PG, Appleton JA. Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis. Infection and Immunity. 81: 1354-63. PMID 23403558 DOI: 10.1128/IAI.01307-12 |
0.353 |
|
| 2012 |
Knezević J, Pavlinić D, Rose WA, Leifer CA, Bendelja K, Gabrilovac J, Parcina M, Lauc G, Kubarenko AV, Petricevic B, Vrbanec D, Bulat-Kardum L, Bekeredjian-Ding I, Pavelić J, Dembić Z, et al. Heterozygous carriage of a dysfunctional Toll-like receptor 9 allele affects CpG oligonucleotide responses in B cells. The Journal of Biological Chemistry. 287: 24544-53. PMID 22613717 DOI: 10.1074/jbc.M111.337477 |
0.423 |
|
| 2012 |
Brooks JC, Sun W, Chiosis G, Leifer CA. Heat shock protein gp96 regulates Toll-like receptor 9 proteolytic processing and conformational stability. Biochemical and Biophysical Research Communications. 421: 780-4. PMID 22554506 DOI: 10.1016/J.Bbrc.2012.04.083 |
0.319 |
|
| 2012 |
Chockalingam A, Rose WA, Hasan M, Ju CH, Leifer CA. Cutting edge: a TLR9 cytoplasmic tyrosine motif is selectively required for proinflammatory cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 188: 527-30. PMID 22174451 DOI: 10.4049/Jimmunol.1102713 |
0.593 |
|
| 2012 |
Chockalingam A, Rose WA, Hasan M, Ju CH, Leifer CA. Cutting edge: A TLR9 cytoplasmic tyrosine motif is selectively required for proinflammatory cytokine production (Journal of Immunology (2012) 188, (527-530)) Journal of Immunology. 188: 3551. DOI: 10.4049/Jimmunol.1290004 |
0.585 |
|
| 2011 |
Hasan M, Ruksznis C, Wang Y, Leifer CA. Antimicrobial peptides inhibit polyinosinic-polycytidylic acid-induced immune responses. Journal of Immunology (Baltimore, Md. : 1950). 187: 5653-9. PMID 22048772 DOI: 10.4049/jimmunol.1102144 |
0.382 |
|
| 2011 |
Chockalingam A, Cameron JL, Brooks JC, Leifer CA. Negative regulation of signaling by a soluble form of toll-like receptor 9. European Journal of Immunology. 41: 2176-84. PMID 21604257 DOI: 10.1002/eji.201041034 |
0.353 |
|
| 2009 |
Ju CH, Chockalingam A, Leifer CA. Early response of mucosal epithelial cells during Toxoplasma gondii infection. Journal of Immunology (Baltimore, Md. : 1950). 183: 7420-7. PMID 19917706 DOI: 10.4049/Jimmunol.0900640 |
0.562 |
|
| 2009 |
Bowdish DM, Sakamoto K, Kim MJ, Kroos M, Mukhopadhyay S, Leifer CA, Tryggvason K, Gordon S, Russell DG. MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis. Plos Pathogens. 5: e1000474. PMID 19521507 DOI: 10.1371/Journal.Ppat.1000474 |
0.401 |
|
| 2009 |
Chockalingam A, Brooks JC, Cameron JL, Blum LK, Leifer CA. TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA. Immunology and Cell Biology. 87: 209-17. PMID 19079358 DOI: 10.1038/Icb.2008.101 |
0.334 |
|
| 2008 |
Semnani RT, Venugopal PG, Leifer CA, Mostböck S, Sabzevari H, Nutman TB. Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites. Blood. 112: 1290-8. PMID 18541719 DOI: 10.1182/Blood-2008-04-149856 |
0.399 |
|
| 2006 |
Leifer CA, Brooks JC, Hoelzer K, Lopez J, Kennedy MN, Mazzoni A, Segal DM. Cytoplasmic targeting motifs control localization of toll-like receptor 9. The Journal of Biological Chemistry. 281: 35585-92. PMID 16990271 DOI: 10.1074/Jbc.M607511200 |
0.362 |
|
| 2005 |
Bafica A, Scanga CA, Feng CG, Leifer C, Cheever A, Sher A. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. The Journal of Experimental Medicine. 202: 1715-24. PMID 16365150 DOI: 10.1084/Jem.20051782 |
0.405 |
|
| 2003 |
Huang LY, Aliberti J, Leifer CA, Segal DM, Sher A, Golenbock DT, Golding B. Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent. Journal of Immunology (Baltimore, Md. : 1950). 171: 1441-6. PMID 12874236 DOI: 10.4049/Jimmunol.171.3.1441 |
0.407 |
|
| 2003 |
Mullen GE, Kennedy MN, Visintin A, Mazzoni A, Leifer CA, Davies DR, Segal DM. The role of disulfide bonds in the assembly and function of MD-2. Proceedings of the National Academy of Sciences of the United States of America. 100: 3919-24. PMID 12642668 DOI: 10.1073/Pnas.0630495100 |
0.328 |
|
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