Alexander Herman - Related publications

Affiliations: 
Baylor College of Medicine, Houston, TX 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Siano G, Varisco M, Scarlatti A, Caiazza MC, Dunville K, Cremisi F, Costa M, Pancrazi L, Di Primio C, Cattaneo A. Gene expression of disease-related genes in Alzheimer's disease is impaired by Tau aggregation. Journal of Molecular Biology. PMID 33058882 DOI: 10.1016/j.jmb.2020.10.009   
2020 Gao J, Chen X, Ma T, He B, Li P, Zhao Y, Ma Y, Zhuang J, Yin Y. PEG-Ceramide Nanomicelles Induce Autophagy and Degrade Tau Proteins in N2a Cells. International Journal of Nanomedicine. 15: 6779-6789. PMID 32982233 DOI: 10.2147/IJN.S258311   
2020 Perea JR, Bolós M, Avila J. Microglia in Alzheimer's Disease in the Context of Tau Pathology. Biomolecules. 10. PMID 33066368 DOI: 10.3390/biom10101439   
2020 Bell BJ, Malvankar MM, Tallon C, Slusher BS. Sowing the Seeds of Discovery: Tau-Propagation Models of Alzheimer's Disease. Acs Chemical Neuroscience. PMID 33050700 DOI: 10.1021/acschemneuro.0c00531   
2020 Baker JD, Uhrich RL, Strovas TJ, Saxton AD, Kraemer BC. AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery. Slas Discovery : Advancing Life Sciences R & D. 2472555220958387. PMID 32981422 DOI: 10.1177/2472555220958387   
2020 Perez-Rando M, Dujardin S, Bennett RE, Commins C, Nibhanupudy T, Hyman BT. Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds. Acta Neuropathologica Communications. 8: 168. PMID 33076986 DOI: 10.1186/s40478-020-01049-7   
2020 Corsetti V, Borreca A, Latina V, Giacovazzo G, Pignataro A, Krashia P, Natale F, Cocco S, Rinaudo M, Malerba F, Florio R, Ciarapica R, Coccurello R, D'Amelio M, Ammassari-Teule M, et al. Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer's disease models. Brain Communications. 2: fcaa039. PMID 32954296 DOI: 10.1093/braincomms/fcaa039   
2020 Narayanan SE, Sekhar N, Rajamma RG, Marathakam A, Al Mamun A, Uddin MS, Mathew B. Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease. Current Protein & Peptide Science. PMID 32957903 DOI: 10.2174/1389203721666200921152246   
2020 Low CYB, Lee JH, Lim FTW, Lee C, Ballard C, Francis PT, Lai MKP, Tan MGK. Isoform-specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias. Brain Pathology (Zurich, Switzerland). e12917. PMID 33128789 DOI: 10.1111/bpa.12917   
2020 Jiang L, Zhao J, Cheng JX, Wolozin B. Tau Oligomers and Fibrils Exhibit Differential Patterns of Seeding and Association With RNA Binding Proteins. Frontiers in Neurology. 11: 579434. PMID 33101187 DOI: 10.3389/fneur.2020.579434   
2020 Pampuscenko K, Morkuniene R, Krasauskas L, Smirnovas V, Tomita T, Borutaite V. Distinct Neurotoxic Effects of Extracellular Tau Species in Primary Neuronal-Glial Cultures. Molecular Neurobiology. PMID 33001416 DOI: 10.1007/s12035-020-02150-7   
2020 Arnsten AFT, Datta D, Tredici KD, Braak H. Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33075193 DOI: 10.1002/alz.12192   
2020 Krishnan S, Shrestha Y, Jayatunga DPW, Rea S, Martins R, Bharadwaj P. Activate or Inhibit? Implications of Autophagy Modulation as a Therapeutic Strategy for Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32937909 DOI: 10.3390/ijms21186739   
2020 Osama A, Zhang J, Yao J, Yao X, Fang J. Nrf2: a dark horse in Alzheimer's disease treatment. Ageing Research Reviews. 101206. PMID 33144124 DOI: 10.1016/j.arr.2020.101206   
2020 Hill E, Wall MJ, Moffat KG, Karikari TK. Understanding the Pathophysiological Actions of Tau Oligomers: A Critical Review of Current Electrophysiological Approaches. Frontiers in Molecular Neuroscience. 13: 155. PMID 32973448 DOI: 10.3389/fnmol.2020.00155   
2020 Caldwell KA, Willicott CW, Caldwell GA. Modeling neurodegeneration in . Disease Models & Mechanisms. 13. PMID 33106318 DOI: 10.1242/dmm.046110   
2020 Al Mamun A, Rahman MM, Zaman S, Munira MS, Uddin MS, Rauf A, Banu N, Ashraf GM. Molecular Insight into the Crosstalk of UPS Components and Alzheimer's Disease. Current Protein & Peptide Science. PMID 32964822 DOI: 10.2174/1389203721666200923153406   
2020 Darwich NF, Phan JM, Kim B, Suh E, Papatriantafyllou JD, Changolkar L, Nguyen AT, O'Rourke CM, He Z, Porta S, Gibbons GS, Luk KC, Papageorgiou SG, Grossman M, Massimo L, et al. Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau. Science (New York, N.Y.). PMID 33004675 DOI: 10.1126/science.aay8826   
2020 Engstrom AK, Walker AC, Moudgal RA, Myrick DA, Kyle SM, Bai Y, Rowley MJ, Katz DJ. The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 33139560 DOI: 10.1073/pnas.2013552117   
2020 Reid MJ, Beltran-Lobo P, Johnson L, Perez-Nievas BG, Noble W. Astrocytes in Tauopathies. Frontiers in Neurology. 11: 572850. PMID 33071951 DOI: 10.3389/fneur.2020.572850   
2020 Ma Y, McClatchy DB, Martínez-Bartolomé S, Bamberger C, Yates JR. Temporal Quantitative Profiling of Newly Synthesized Proteins during Aβ Accumulation. Journal of Proteome Research. PMID 33147027 DOI: 10.1021/acs.jproteome.0c00645   
2020 Gibbons GS, Kim SJ, Wu Q, Riddle DM, Leight SN, Changolkar L, Xu H, Meymand ES, O'Reilly M, Zhang B, Brunden KR, Trojanowski JQ, Lee VMY. Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease. Molecular Neurodegeneration. 15: 64. PMID 33148293 DOI: 10.1186/s13024-020-00404-5   
2020 Sopko R, Golonzhka O, Arndt J, Quan C, Czerkowicz J, Cameron A, Smith B, Murugesan Y, Gibbons G, Kim SJ, Trojanowski JQ, Lee VMY, Brunden KR, Weinreb PH, Graham DL, et al. Characterization of tau binding by gosuranemab. Neurobiology of Disease. 105120. PMID 32991997 DOI: 10.1016/j.nbd.2020.105120   
2020 Calvo-Rodriguez M, García-Rodríguez C, Villalobos C, Núñez L. Role of Toll Like Receptor 4 in Alzheimer's Disease. Frontiers in Immunology. 11: 1588. PMID 32983082 DOI: 10.3389/fimmu.2020.01588   
2020 Zamudio F, Loon AR, Smeltzer S, Benyamine K, Navalpur Shanmugam NK, Stewart NJF, Lee DC, Nash K, Selenica MB. TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model. Journal of Neuroinflammation. 17: 283. PMID 32979923 DOI: 10.1186/s12974-020-01952-9   
2020 Scholes HM, Cryar A, Kerr F, Sutherland D, Gethings LA, Vissers JPC, Lees JG, Orengo CA, Partridge L, Thalassinos K. Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila. Scientific Reports. 10: 18517. PMID 33116184 DOI: 10.1038/s41598-020-74748-9   
2020 Zhu F, Li C, Chu F, Tian X, Zhu J. Target Dysbiosis of Gut Microbes as a Future Therapeutic Manipulation in Alzheimer's Disease. Frontiers in Aging Neuroscience. 12: 544235. PMID 33132894 DOI: 10.3389/fnagi.2020.544235   
2020 Trzeciakiewicz H, Ajit D, Tseng JH, Chen Y, Ajit A, Tabassum Z, Lobrovich R, Peterson C, Riddick NV, Itano MS, Tripathy A, Moy SS, Lee VMY, Trojanowski JQ, Irwin DJ, et al. An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline. Nature Communications. 11: 5522. PMID 33139698 DOI: 10.1038/s41467-020-19317-4   
2020 Mangleburg CG, Wu T, Yalamanchili HK, Guo C, Hsieh YC, Duong DM, Dammer EB, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Molecular Neurodegeneration. 15: 56. PMID 32993812 DOI: 10.1186/s13024-020-00405-4   
2020 Lemke N, Melis V, Lauer D, Magbagbeolu M, Neumann B, Harrington CR, Riedel G, Wischik CM, Theuring F, Schwab K. Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia. The Journal of Biological Chemistry. PMID 33127647 DOI: 10.1074/jbc.RA120.014890   
2020 Stevenson R, Samokhina E, Rossetti I, Morley JW, Buskila Y. Neuromodulation of Glial Function During Neurodegeneration. Frontiers in Cellular Neuroscience. 14: 278. PMID 32973460 DOI: 10.3389/fncel.2020.00278   
2020 d'Abramo C, D'Adamio L, Giliberto L. Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: Sensitivity, Specificity and Potential for Clinical Use. Journal of Personalized Medicine. 10. PMID 32911755 DOI: 10.3390/jpm10030116   
2020 Mondragón-Rodríguez S, Salgado-Burgos H, Peña-Ortega F. Circuitry and Synaptic Dysfunction in Alzheimer's Disease: A New Tau Hypothesis. Neural Plasticity. 2020: 2960343. PMID 32952546 DOI: 10.1155/2020/2960343   
2020 Limegrover CS, LeVine H, Izzo NJ, Yurko R, Mozzoni K, Rehak C, Sadlek K, Safferstein H, Catalano SM. Alzheimer's Protection Effect of A673T Mutation May Be Driven by Lower Aβ Oligomer Binding Affinity. Journal of Neurochemistry. PMID 33025581 DOI: 10.1111/jnc.15212   
2020 Wang L, Bharti, Kumar R, Pavlov PF, Winblad B. Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance. European Journal of Medicinal Chemistry. 112915. PMID 33139110 DOI: 10.1016/j.ejmech.2020.112915   
2020 Gan KJ, Akram A, Blasius TL, Ramser EM, Budaitis BG, Gabrych DR, Verhey KJ, Silverman MA. GSK3ß impairs KIF1A transport in a cellular model of Alzheimer's disease but does not regulate motor motility at S402. Eneuro. PMID 33067366 DOI: 10.1523/ENEURO.0176-20.2020   
2020 Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z. The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro. Free Radical Biology & Medicine. PMID 33131696 DOI: 10.1016/j.freeradbiomed.2020.10.003   
2020 Dhanwani R, Pham J, Premlal ALR, Frazier A, Kumar A, Pero ME, Bartolini F, Dutra JR, Marder KS, Peters B, Sulzer D, Sette A, Lindestam Arlehamn CS. T Cell Responses to Neural Autoantigens Are Similar in Alzheimer's Disease Patients and Age-Matched Healthy Controls. Frontiers in Neuroscience. 14: 874. PMID 32982670 DOI: 10.3389/fnins.2020.00874   
2020 Goedert M. Tau proteinopathies and the prion concept. Progress in Molecular Biology and Translational Science. 175: 239-259. PMID 32958235 DOI: 10.1016/bs.pmbts.2020.08.003   
2020 Qu X, Guan P, Han L, Wang Z, Huang X. Levistolide A Attenuates Alzheimer's Pathology Through Activation of the PPARγ Pathway. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33034847 DOI: 10.1007/s13311-020-00943-1   
2020 Braun NJ, Yao KR, Alford PW, Liao D. Mechanical injuries of neurons induce tau mislocalization to dendritic spines and tau-dependent synaptic dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 33139536 DOI: 10.1073/pnas.2008306117   
2020 Wu Q, Bai Y, Li W, Congdon EE, Liu W, Lin Y, Ji C, Gan WB, Sigurdsson EM. Increased neuronal activity in motor cortex reveals prominent calcium dyshomeostasis in tauopathy mice. Neurobiology of Disease. 105165. PMID 33166699 DOI: 10.1016/j.nbd.2020.105165   
2020 Cazzaniga FA, De Luca CMG, Bistaffa E, Consonni A, Legname G, Giaccone G, Moda F. Cell-free amplification of prions: Where do we stand? Progress in Molecular Biology and Translational Science. 175: 325-358. PMID 32958239 DOI: 10.1016/bs.pmbts.2020.08.005   
2020 Tennant JM, Henderson DM, Wisniewski TM, Hoover EA. RT-QuIC detection of tauopathies using full-length tau substrates. Prion. 14: 249-256. PMID 33171070 DOI: 10.1080/19336896.2020.1832946   
2020 Neves JF, Petrvalská O, Bosica F, Cantrelle FX, Merzougui H, O'Mahony G, Hanoulle X, Obšil T, Landrieu I. Phosphorylated full-length Tau interacts with 14-3-3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14-3-3 dimer. The Febs Journal. PMID 32979285 DOI: 10.1111/febs.15574   
2020 Jo M, Lee S, Jeon YM, Kim S, Kwon Y, Kim HJ. The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies. Experimental & Molecular Medicine. PMID 33051572 DOI: 10.1038/s12276-020-00513-7   
2020 Masuda-Suzukake M, Suzuki G, Hosokawa M, Nonaka T, Goedert M, Hasegawa M. Dextran sulphate-induced tau assemblies cause endogenous tau aggregation and propagation in wild-type mice. Brain Communications. 2: fcaa091. PMID 33005889 DOI: 10.1093/braincomms/fcaa091   
2020 Alam J. Vitamins: a nutritional intervention to modulate the Alzheimer's disease progression. Nutritional Neuroscience. 1-18. PMID 32998670 DOI: 10.1080/1028415X.2020.1826762   
2020 Montalbano M, McAllen S, Cascio FL, Sengupta U, Garcia S, Bhatt N, Ellsworth A, Heidelman EA, Johnson OD, Doskocil S, Kayed R. TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia. Neurobiology of Disease. 146: 105130. PMID 33065281 DOI: 10.1016/j.nbd.2020.105130   
2020 Yang Q, Jiao B, Shen L. The Development of C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Disorders. Frontiers in Genetics. 11: 562758. PMID 32983232 DOI: 10.3389/fgene.2020.562758