Kirk Thomas, Ph.D. - Publications

Affiliations: 
University of Utah, Salt Lake City, UT 

26/57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Chojnowski JL, Masuda K, Trau HA, Thomas K, Capecchi M, Manley NR. Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse. Development (Cambridge, England). 141: 3697-708. PMID 25249461 DOI: 10.1242/Dev.110833  0.582
2011 Troadec MB, Warner D, Wallace J, Thomas K, Spangrude GJ, Phillips J, Khalimonchuk O, Paw BH, Ward DM, Kaplan J. Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria. Blood. 117: 5494-502. PMID 21310927 DOI: 10.1182/Blood-2010-11-319483  0.334
2010 Znosko WA, Yu S, Thomas K, Molina GA, Li C, Tsang W, Dawid IB, Moon AM, Tsang M. Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development. Developmental Biology. 342: 11-25. PMID 20346941 DOI: 10.1016/J.Ydbio.2010.03.011  0.316
2007 Barrow JR, Howell WD, Rule M, Hayashi S, Thomas KR, Capecchi MR, McMahon AP. Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Developmental Biology. 312: 312-20. PMID 18028899 DOI: 10.1016/J.Ydbio.2007.09.030  0.479
2005 Jarvis M, Iyer RK, Williams LO, Noll WW, Thomas K, Telatar M, Grody WW. A novel method for creating artificial mutant samples for performance evaluation and quality control in clinical molecular genetics. The Journal of Molecular Diagnostics : Jmd. 7: 247-51. PMID 15858148 DOI: 10.1016/S1525-1578(10)60551-X  0.383
2003 Gaufo GO, Thomas KR, Capecchi MR. Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneurons. Development (Cambridge, England). 130: 5191-201. PMID 12954718 DOI: 10.1242/Dev.00730  0.524
2003 Barrow JR, Thomas KR, Boussadia-Zahui O, Moore R, Kemler R, Capecchi MR, McMahon AP. Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes & Development. 17: 394-409. PMID 12569130 DOI: 10.1101/Gad.1044903  0.43
2000 Greer JM, Puetz J, Thomas KR, Capecchi MR. Maintenance of functional equivalence during paralogous Hox gene evolution. Nature. 403: 661-5. PMID 10688203 DOI: 10.1038/35001077  0.573
1999 Bunting M, Bernstein KE, Greer JM, Capecchi MR, Thomas KR. Targeting genes for self-excision in the germ line. Genes & Development. 13: 1524-8. PMID 10385621 DOI: 10.1101/Gad.13.12.1524  0.587
1997 Kelley TJ, Thomas K, Milgram LJ, Drumm ML. In vivo activation of the cystic fibrosis transmembrane conductance regulator mutant deltaF508 in murine nasal epithelium. Proceedings of the National Academy of Sciences of the United States of America. 94: 2604-8. PMID 9122242 DOI: 10.1073/Pnas.94.6.2604  0.349
1997 Thomas KR, Capecchi MR. Recombinant DNA technique and sickle cell anemia research. Science (New York, N.Y.). 275: 1404-5. PMID 9072801 DOI: 10.1126/science.275.5305.1401e  0.487
1995 Zeiher BG, Eichwald E, Zabner J, Smith JJ, Puga AP, McCray PB, Capecchi MR, Welsh MJ, Thomas KR. A mouse model for the delta F508 allele of cystic fibrosis. The Journal of Clinical Investigation. 96: 2051-64. PMID 7560099 DOI: 10.1172/Jci118253  0.467
1994 Thomas KR. Targeted Mutagenesis of Mouse Developmental Genes Journal of Animal Science. 72: 1-8. DOI: 10.2527/1994.72suppl_31x  0.357
1993 Deng C, Thomas KR, Capecchi MR. Location of crossovers during gene targeting with insertion and replacement vectors. Molecular and Cellular Biology. 13: 2134-40. PMID 8455602 DOI: 10.1128/MCB.13.4.2134  0.586
1992 Thomas KR, Deng C, Capecchi MR. High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Molecular and Cellular Biology. 12: 2919-23. PMID 1620105 DOI: 10.1128/MCB.12.7.2919  0.59
1991 Thomas KR, Musci TS, Neumann PE, Capecchi MR. Swaying is a mutant allele of the proto-oncogene Wnt-1. Cell. 67: 969-76. PMID 1835670 DOI: 10.1016/0092-8674(91)90369-A  0.546
1990 Thomas KR, Capecchi MR. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature. 346: 847-50. PMID 2202907 DOI: 10.1038/346847a0  0.606
1990 Mansour SL, Thomas KR, Deng CX, Capecchi MR. Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 87: 7688-92. PMID 2120706 DOI: 10.1073/Pnas.87.19.7688  0.628
1988 Mansour SL, Thomas KR, Capecchi MR. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature. 336: 348-52. PMID 3194019 DOI: 10.1038/336348A0  0.636
1987 Thomas KR, Capecchi MR. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell. 51: 503-12. PMID 2822260 DOI: 10.1016/0092-8674(87)90646-5  0.621
1986 Thomas KR, Capecchi MR. Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene. Nature. 324: 34-8. PMID 3785372 DOI: 10.1038/324034a0  0.603
1986 Thomas KR, Capecchi MR. Targeting of genes to specific sites in the mammalian genome. Cold Spring Harbor Symposia On Quantitative Biology. 51: 1101-13. PMID 3472755 DOI: 10.1101/SQB.1986.051.01.128  0.511
1986 Thomas KR, Folger KR, Capecchi MR. High frequency targeting of genes to specific sites in the mammalian genome. Cell. 44: 419-28. PMID 3002636 DOI: 10.1016/0092-8674(86)90463-0  0.611
1985 Folger KR, Thomas K, Capecchi MR. Efficient correction of mismatched bases in plasmid heteroduplexes injected into cultured mammalian cell nuclei. Molecular and Cellular Biology. 5: 70-4. PMID 3982420 DOI: 10.1128/Mcb.5.1.70  0.615
1985 Folger KR, Thomas K, Capecchi MR. Nonreciprocal exchanges of information between DNA duplexes coinjected into mammalian cell nuclei. Molecular and Cellular Biology. 5: 59-69. PMID 2984556 DOI: 10.1128/Mcb.5.1.59  0.599
1984 Folger K, Thomas K, Capecchi MR. Analysis of homologous recombination in cultured mammalian cells. Cold Spring Harbor Symposia On Quantitative Biology. 49: 123-38. PMID 6099232 DOI: 10.1101/Sqb.1984.049.01.016  0.521
Low-probability matches (unlikely to be authored by this person)
2012 Malenke JR, Magnanou E, Thomas K, Dearing MD. Cytochrome P450 2B diversity and dietary novelty in the herbivorous, desert woodrat (Neotoma lepida). Plos One. 7: e41510. PMID 22927909 DOI: 10.1371/Journal.Pone.0041510  0.299
1994 Thomas KR. Impact of gene targeting on medicine Molecular Genetic Medicine. 4: 153-178. PMID 7981629 DOI: 10.1016/B978-0-12-462004-9.50009-8  0.278
2018 Song NJ, Chang SH, Kim S, Panic V, Jang BH, Yun UJ, Choi JH, Li Z, Park KM, Yoon JH, Kim S, Yoo JH, Ling J, Thomas K, Villanueva CJ, et al. PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice. Cell Death & Disease. 9: 876. PMID 30158592 DOI: 10.1038/S41419-018-0904-3  0.255
2008 Navankasattusas S, Whitehead KJ, Suli A, Sorensen LK, Lim AH, Zhao J, Park KW, Wythe JD, Thomas KR, Chien CB, Li DY. The netrin receptor UNC5B promotes angiogenesis in specific vascular beds. Development (Cambridge, England). 135: 659-67. PMID 18223200 DOI: 10.1242/Dev.013623  0.255
2013 Frank DU, Emechebe U, Thomas KR, Moon AM. Mouse TBX3 mutants suggest novel molecular mechanisms for Ulnar-mammary syndrome. Plos One. 8: e67841. PMID 23844108 DOI: 10.1371/Journal.Pone.0067841  0.249
2011 Maselli RA, Arredondo J, Cagney O, Mozaffar T, Skinner S, Yousif S, Davis RR, Gregg JP, Sivak M, Konia TH, Thomas K, Wollmann RL. Congenital myasthenic syndrome associated with epidermolysis bullosa caused by homozygous mutations in PLEC1 and CHRNE. Clinical Genetics. 80: 444-51. PMID 21175599 DOI: 10.1111/j.1399-0004.2010.01602.x  0.246
2013 Luo L, Uehara H, Zhang X, Das SK, Olsen T, Holt D, Simonis JM, Jackman K, Singh N, Miya TR, Huang W, Ahmed F, Bastos-Carvalho A, Le YZ, Mamalis C, ... ... Thomas K, et al. Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. Elife. 2: e00324. PMID 23795287 DOI: 10.7554/Elife.00324  0.218
2012 Frank DU, Carter KL, Thomas KR, Burr RM, Bakker ML, Coetzee WA, Tristani-Firouzi M, Bamshad MJ, Christoffels VM, Moon AM. Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 109: E154-63. PMID 22203979 DOI: 10.1073/Pnas.1115165109  0.216
2001 Phillips JD, Jackson LK, Bunting M, Franklin MR, Thomas KR, Levy JE, Andrews NC, Kushner JP. A mouse model of familial porphyria cutanea tarda Proceedings of the National Academy of Sciences. 98: 259-264. DOI: 10.1073/Pnas.98.1.259  0.189
1983 Hedgcoth C, Hayenga K, Scheets K, Thomas KR, Harrison M, Lin VK, Ortwerth BJ. Perturbation of the mitochondrial lysine tRNA population by virus-induced transformation or stress of mammalian cells: functional properties and nucleotide sequence of a mitochondrially associated lysine tRNA. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 84: 171-83. PMID 6342072 DOI: 10.1007/978-3-642-81947-6_12  0.182
2013 Luo L, Uehara H, Zhang X, Das SK, Olsen T, Holt D, Simonis JM, Jackman K, Singh N, Miya TR, Huang W, Ahmed F, Bastos-Carvalho A, Le YZ, Mamalis C, ... ... Thomas K, et al. Author response: Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1 Elife. DOI: 10.7554/Elife.00324.034  0.169
2011 Larrieu-Lahargue F, Welm AL, Thomas KR, Li DY. Netrin-4 activates endothelial integrin {alpha}6{beta}1. Circulation Research. 109: 770-4. PMID 21799154 DOI: 10.1161/CIRCRESAHA.111.247239  0.158
2013 Grossmann AH, Yoo JH, Clancy J, Sorensen LK, Sedgwick A, Tong Z, Ostanin K, Rogers A, Grossmann KF, Tripp SR, Thomas KR, D'Souza-Schorey C, Odelberg SJ, Li DY. The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis. Science Signaling. 6: ra14. PMID 23462101 DOI: 10.1126/Scisignal.2003398  0.149
2016 Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, ... ... Thomas KR, et al. ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma. Cancer Cell. PMID 27265506 DOI: 10.1016/J.Ccell.2016.04.015  0.144
2012 Zhu W, London NR, Gibson CC, Davis CT, Tong Z, Sorensen LK, Shi DS, Guo J, Smith MC, Grossmann AH, Thomas KR, Li DY. Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability. Nature. 492: 252-5. PMID 23143332 DOI: 10.1038/Nature11603  0.127
2010 Larrieu-Lahargue F, Welm AL, Thomas KR, Li DY. Netrin-4 induces lymphangiogenesis in vivo. Blood. 115: 5418-26. PMID 20407033 DOI: 10.1182/blood-2009-11-252338  0.127
1979 Thomas KR, Manlapaz-Ramos P, Lundquist R, Olivera BM. Formation of Okazaki pieces at the Escherichia coli replication fork in vitro Cold Spring Harbor Symposia On Quantitative Biology. 43: 231-237. PMID 38946 DOI: 10.1101/SQB.1979.043.01.028  0.121
2021 London NR, Tharakan A, Smith A, Thomas KR, Zhu W, Odelberg SJ, Ramanathan M, Lane AP. Deletion of Reduces Eosinophilic Inflammation and Interleukin-5 Expression in a Murine Model of Rhinitis. Ear, Nose, & Throat Journal. 145561320986055. PMID 33393815 DOI: 10.1177/0145561320986055  0.114
2009 Jones CA, Nishiya N, London NR, Zhu W, Sorensen LK, Chan AC, Lim CJ, Chen H, Zhang Q, Schultz PG, Hayallah AM, Thomas KR, Famulok M, Zhang K, Ginsberg MH, et al. Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity. Nature Cell Biology. 11: 1325-31. PMID 19855388 DOI: 10.1038/Ncb1976  0.107
2006 Wilson BD, Ii M, Park KW, Suli A, Sorensen LK, Larrieu-Lahargue F, Urness LD, Suh W, Asai J, Kock GA, Thorne T, Silver M, Thomas KR, Chien CB, Losordo DW, et al. Netrins promote developmental and therapeutic angiogenesis. Science (New York, N.Y.). 313: 640-4. PMID 16809490 DOI: 10.1126/Science.1124704  0.106
2017 Zhu W, Shi DS, Winter JM, Rich BE, Tong Z, Sorensen LK, Zhao H, Huang Y, Tai Z, Mleynek TM, Yoo JH, Dunn C, Ling J, Bergquist JA, Richards JR, ... ... Thomas KR, et al. Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy. The Journal of Clinical Investigation. PMID 29058688 DOI: 10.1172/Jci91770  0.103
2022 Sun Z, Zhao H, Fang D, Davis CT, Shi DS, Lei K, Rich BE, Winter JM, Guo L, Sorensen LK, Pryor RJ, Zhu N, Lu S, Dickey LL, Doty DJ, ... ... Thomas KR, et al. Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling. Neuron. PMID 35961320 DOI: 10.1016/j.neuron.2022.07.015  0.094
2015 Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, et al. Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation. Circulation. 131: 289-99. PMID 25486933 DOI: 10.1161/Circulationaha.114.010403  0.088
1995 Thomas KR. The knockout mouse: six years old and growing stronger American Journal of Respiratory Cell and Molecular Biology. 12: 461-463. PMID 7742010 DOI: 10.1165/ajrcmb.12.5.7742010  0.075
2015 Gibson CC, Davis CT, Zhu W, Bowman-Kirigin JA, Walker AE, Tai Z, Thomas KR, Donato AJ, Lesniewski LA, Li DY. Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium. Plos One. 10: e0140370. PMID 26469335 DOI: 10.1371/Journal.Pone.0140370  0.068
1983 Thomas KR, Olivera BM. Flexbility in RNA priming of okazald pieces at the E. coli replication fork Nucleic Acids Research. 11: 6531-6539. PMID 6194511 DOI: 10.1093/nar/11.18.6531  0.063
1987 Robbins RA, Russ WD, Thomas KR, Rasmussen JK, Kay HD. Complement component C5 is required for release of alveolar macrophage-derived neutrophil chemotactic activity American Review of Respiratory Disease. 135: 659-664. PMID 3826892 DOI: 10.1164/arrd.1987.135.3.659  0.06
1988 Hughes HP, Thomas KR, Speer CA. Antigen-specific lymphocyte transformation induced by oocyst antigens of Eimeria bovis. Infection and Immunity. 56: 1518-1525. DOI: 10.1128/iai.56.6.1518-1525.1988  0.057
2012 Larrieu-Lahargue F, Thomas KR, Li DY. Netrin ligands and receptors: lessons from neurons to the endothelium. Trends in Cardiovascular Medicine. 22: 44-7. PMID 22841834 DOI: 10.1016/j.tcm.2012.06.010  0.045
1994 KNAPP JF, THOMAS KR, MATHEWS R, WASSERMAN G. Case 06–1994 Pediatric Emergency Care. 10: 364-368. DOI: 10.1097/00006565-199412000-00016  0.013
2006 Simpson JA, Thomas K, Grgurinovic CA. Uredinales species pathogenic on species of Myrtaceae Australasian Plant Pathology. 35: 549. DOI: 10.1071/AP06057  0.01
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