Year |
Citation |
Score |
2022 |
Luo JE, Li YM. Turning the tide on Alzheimer's disease: modulation of γ-secretase. Cell & Bioscience. 12: 2. PMID 34983641 DOI: 10.1186/s13578-021-00738-7 |
0.428 |
|
2021 |
Xu P, Chang JC, Zhou X, Wang W, Bamkole M, Wong E, Bettayeb K, Jiang LL, Huang T, Luo W, Xu H, Nairn AC, Flajolet M, Ip NY, Li YM, et al. GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. The Journal of Experimental Medicine. 218. PMID 34156424 DOI: 10.1084/jem.20202446 |
0.311 |
|
2020 |
Mekala S, Nelson G, Li YM. Recent developments of small molecule γ-secretase modulators for Alzheimer's disease. Rsc Medicinal Chemistry. 11: 1003-1022. PMID 33479693 DOI: 10.1039/d0md00196a |
0.402 |
|
2020 |
Wong E, Frost GR, Li YM. γ-Secretase Modulatory Proteins: The Guiding Hand Behind the Running Scissors. Frontiers in Aging Neuroscience. 12: 614690. PMID 33343338 DOI: 10.3389/fnagi.2020.614690 |
0.446 |
|
2020 |
Sinha A, Chang JC, Xu P, Gindinova K, Cho Y, Sun W, Wu X, Li YM, Greengard P, Kelly JW, Sinha SC. Brain Permeable Tafamidis Amide Analogs for Stabilizing TTR and Reducing APP Cleavage. Acs Medicinal Chemistry Letters. 11: 1973-1979. PMID 33062181 DOI: 10.1021/acsmedchemlett.9b00688 |
0.31 |
|
2020 |
Hur JY, Frost GR, Wu X, Crump C, Pan SJ, Wong E, Barros M, Li T, Nie P, Zhai Y, Wang JC, Tcw J, Guo L, McKenzie A, Ming C, ... Li YM, et al. The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease. Nature. PMID 32879487 DOI: 10.1038/S41586-020-2681-2 |
0.496 |
|
2020 |
Luo W, Ip FCF, Fu G, Cheung K, Tian Y, Hu Y, Sinha A, Cheng EYL, Wu X, Bustos V, Greengard P, Li YM, Sinha SC, Ip NY. A pentacyclic triterpene from targets γ-secretase. Acs Chemical Neuroscience. PMID 32786303 DOI: 10.1021/Acschemneuro.0C00389 |
0.516 |
|
2020 |
Nie P, Vartak A, Li YM. γ-Secretase inhibitors and modulators: Mechanistic insights into the function and regulation of γ-Secretase. Seminars in Cell & Developmental Biology. PMID 32249070 DOI: 10.1016/j.semcdb.2020.03.002 |
0.659 |
|
2020 |
Zhao J, Xiao Y, Liu X, Kim S, Wu X, Barros M, Zhuang R, Hou X, Zhang Y, Robakis NK, Li YM, Dordick JS, Ubarretxena-Belandia I, Wang C. Substrate interaction inhibits γ-secretase production of amyloid-β peptides. Chemical Communications (Cambridge, England). PMID 32016207 DOI: 10.1039/C9Cc09170J |
0.32 |
|
2019 |
Wong E, Liao GP, Chang JC, Xu P, Li YM, Greengard P. GSAP modulates γ-secretase specificity by inducing conformational change in PS1. Proceedings of the National Academy of Sciences of the United States of America. PMID 30850537 DOI: 10.1073/pnas.1820160116 |
0.373 |
|
2019 |
Yusof HH, Lee HC, Seth EA, Wu X, Hewitt CA, Scott HS, Cheah PS, Li YM, Chau DM, Ling KH. Expression Profiling of Notch Signalling Pathway and Gamma-Secretase Activity in the Brain of Ts1Cje Mouse Model of Down Syndrome. Journal of Molecular Neuroscience : Mn. PMID 30758748 DOI: 10.1007/s12031-019-01275-2 |
0.737 |
|
2019 |
Zhao J, Xiao Y, Liu X, Kim S, Wu X, Barros M, Zhuang M, Robakis NK, Li Y, Wang C. SUBSTRATE BINDING INHIBITS γ-SECRETASE CLEAVAGE OF AMYLOID PRECURSOR PROTEIN Alzheimers & Dementia. 15: 1595. DOI: 10.1016/J.Jalz.2019.09.052 |
0.454 |
|
2017 |
Frost GR, Li YM. The role of astrocytes in amyloid production and Alzheimer's disease. Open Biology. 7. PMID 29237809 DOI: 10.1098/rsob.170228 |
0.333 |
|
2017 |
Frost GR, Wong E, Li YM. Versatility of presenilin 1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28645897 DOI: 10.1073/pnas.1707809114 |
0.303 |
|
2017 |
Johnson DS, Li YM, Pettersson M, St George-Hyslop PH. Structural and Chemical Biology of Presenilin Complexes. Cold Spring Harbor Perspectives in Medicine. PMID 28320827 DOI: 10.1101/Cshperspect.A024067 |
0.468 |
|
2017 |
Gertsik N, Am Ende CW, Geoghegan KF, Nguyen C, Mukherjee P, Mente S, Seneviratne U, Johnson DS, Li YM. Mapping the Binding Site of BMS-708163 on γ-Secretase with Cleavable Photoprobes. Cell Chemical Biology. PMID 28065657 DOI: 10.1016/J.Chembiol.2016.12.006 |
0.462 |
|
2016 |
Crump CJ, Murrey HE, Ballard TE, Am Ende CW, Wu X, Gertsik N, Johnson DS, Li YM. Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase. Acs Chemical Neuroscience. PMID 27253220 DOI: 10.1021/Acschemneuro.6B00127 |
0.478 |
|
2016 |
Carroll CM, Li YM. Physiological and pathological roles of the γ-secretase complex. Brain Research Bulletin. PMID 27133790 DOI: 10.1016/j.brainresbull.2016.04.019 |
0.426 |
|
2016 |
Zhang X, Sullivan E, Scimeca M, Wu X, Li YM, Sisodia SS. Evidence that the "Lid" Domain of Nicastrin Is Not Essential for Regulating γ-Secretase Activity. The Journal of Biological Chemistry. PMID 26887941 DOI: 10.1074/Jbc.C115.701649 |
0.458 |
|
2015 |
Gilchrist ML, Ahn K, Li YM. Imaging and Functional Analysis of γ-Secretase and Substrate in a Proteolipobead System with an Activity-Based Probe. Analytical Chemistry. PMID 26699370 DOI: 10.1021/Acs.Analchem.5B03762 |
0.38 |
|
2015 |
Gertsik N, Chau DM, Li YM. γ-Secretase Inhibitors and Modulators Induce Distinct Conformational Changes in the Active Sites of γ-Secretase and Signal Peptide Peptidase. Acs Chemical Biology. 10: 1925-31. PMID 26030233 DOI: 10.1021/acschembio.5b00321 |
0.78 |
|
2015 |
Dang S, Wu S, Wang J, Li H, Huang M, He W, Li YM, Wong CC, Shi Y. Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH. Proceedings of the National Academy of Sciences of the United States of America. 112: 3344-9. PMID 25733893 DOI: 10.1073/Pnas.1502150112 |
0.488 |
|
2014 |
Gertsik N, Chiu D, Li YM. Complex regulation of γ-secretase: from obligatory to modulatory subunits. Frontiers in Aging Neuroscience. 6: 342. PMID 25610395 DOI: 10.3389/Fnagi.2014.00342 |
0.554 |
|
2014 |
Zhang X, Hoey R, Koide A, Dolios G, Paduch M, Nguyen P, Wu X, Li Y, Wagner SL, Wang R, Koide S, Sisodia SS. A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of γ-secretase. The Journal of Biological Chemistry. 289: 34851-61. PMID 25352592 DOI: 10.1074/Jbc.M114.609636 |
0.511 |
|
2014 |
Villa JC, Chiu D, Brandes AH, Escorcia FE, Villa CH, Maguire WF, Hu CJ, de Stanchina E, Simon MC, Sisodia SS, Scheinberg DA, Li YM. Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer. Cell Reports. 8: 1077-92. PMID 25131208 DOI: 10.1016/J.Celrep.2014.07.028 |
0.414 |
|
2014 |
Gertsik N, Ballard TE, Am Ende CW, Johnson DS, Li YM. Development of CBAP-BPyne, a probe for γ-secretase and presenilinase. Medchemcomm. 5: 338-341. PMID 24914408 DOI: 10.1039/C3Md00281K |
0.499 |
|
2014 |
Minuesa G, Antczak C, Shum D, Radu C, Bhinder B, Li Y, Djaballah H, Kharas MG. A 1536-well fluorescence polarization assay to screen for modulators of the MUSASHI family of RNA-binding proteins. Combinatorial Chemistry & High Throughput Screening. 17: 596-609. PMID 24912481 DOI: 10.2174/1386207317666140609122714 |
0.316 |
|
2014 |
Wagner SL, Zhang C, Cheng S, Nguyen P, Zhang X, Rynearson KD, Wang R, Li Y, Sisodia SS, Mobley WC, Tanzi RE. Soluble γ-secretase modulators selectively inhibit the production of the 42-amino acid amyloid β peptide variant and augment the production of multiple carboxy-truncated amyloid β species. Biochemistry. 53: 702-13. PMID 24401146 DOI: 10.1021/Bi401537V |
0.452 |
|
2014 |
Chen W, Gamache E, Rosenman DJ, Xie J, Lopez MM, Li YM, Wang C. Familial Alzheimer's mutations within APPTM increase Aβ42 production by enhancing accessibility of ε-cleavage site. Nature Communications. 5: 3037. PMID 24390130 DOI: 10.1038/Ncomms4037 |
0.339 |
|
2013 |
Crump CJ, Johnson DS, Li YM. Development and mechanism of γ-secretase modulators for Alzheimer's disease. Biochemistry. 52: 3197-216. PMID 23614767 DOI: 10.1021/Bi400377P |
0.56 |
|
2013 |
Chau DM, Shum D, Radu C, Bhinder B, Gin D, Gilchrist ML, Djaballah H, Li YM. A novel high throughput 1536-well notch1 γsecretase AlphaLISA assay Combinatorial Chemistry and High Throughput Screening. 16: 415-424. PMID 23448293 DOI: 10.2174/1386207311316060001 |
0.758 |
|
2013 |
Pozdnyakov N, Murrey HE, Crump CJ, Pettersson M, Ballard TE, Am Ende CW, Ahn K, Li YM, Bales KR, Johnson DS. γ-Secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin. The Journal of Biological Chemistry. 288: 9710-20. PMID 23396974 DOI: 10.1074/Jbc.M112.398602 |
0.492 |
|
2013 |
Li Y. Endogenous and exogenous regulation of gamma-secretase Molecular Neurodegeneration. 8: 1-1. DOI: 10.1186/1750-1326-8-S1-O10 |
0.552 |
|
2012 |
Crump CJ, Castro SV, Wang F, Pozdnyakov N, Ballard TE, Sisodia SS, Bales KR, Johnson DS, Li YM. BMS-708,163 targets presenilin and lacks notch-sparing activity. Biochemistry. 51: 7209-11. PMID 22931393 DOI: 10.1021/Bi301137H |
0.432 |
|
2012 |
Zhang X, Hoey RJ, Lin G, Koide A, Leung B, Ahn K, Dolios G, Paduch M, Ikeuchi T, Wang R, Li YM, Koide S, Sisodia SS. Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies. Proceedings of the National Academy of Sciences of the United States of America. 109: 8534-9. PMID 22586122 DOI: 10.1073/Pnas.1202691109 |
0.401 |
|
2012 |
Chau DM, Crump CJ, Villa JC, Scheinberg DA, Li YM. Familial Alzheimer disease presenilin-1 mutations alter the active site conformation of γ-secretase. The Journal of Biological Chemistry. 287: 17288-96. PMID 22461631 DOI: 10.1074/Jbc.M111.300483 |
0.78 |
|
2012 |
Crump CJ, am Ende CW, Ballard TE, Pozdnyakov N, Pettersson M, Chau DM, Bales KR, Li YM, Johnson DS. Development of clickable active site-directed photoaffinity probes for γ-secretase. Bioorganic & Medicinal Chemistry Letters. 22: 2997-3000. PMID 22418280 DOI: 10.1016/J.Bmcl.2012.02.027 |
0.755 |
|
2012 |
Li Y. Gamma-secretase: from pathogenesis to therapeutics. Molecular Neurodegeneration. 7: 1-1. DOI: 10.1186/1750-1326-7-S1-L4 |
0.469 |
|
2011 |
Crump CJ, Fish BA, Castro SV, Chau DM, Gertsik N, Ahn K, Stiff C, Pozdnyakov N, Bales KR, Johnson DS, Li YM. Piperidine acetic acid based γ-secretase modulators directly bind to Presenilin-1. Acs Chemical Neuroscience. 2: 705-710. PMID 22229075 DOI: 10.1021/Cn200098P |
0.795 |
|
2011 |
Li T, Li YM, Ahn K, Price DL, Sisodia SS, Wong PC. Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo. Plos One. 6: e28179. PMID 22140537 DOI: 10.1371/Journal.Pone.0028179 |
0.395 |
|
2011 |
Crump CJ, Johnson DS, Li YM. Target of γ-secretase modulators, presenilin marks the spot. The Embo Journal. 30: 4696-8. PMID 22126818 DOI: 10.1038/Emboj.2011.410 |
0.49 |
|
2011 |
Antczak C, Shum D, Bassit B, Frattini MG, Li Y, de Stanchina E, Scheinberg DA, Djaballah H. Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase. Bioorganic & Medicinal Chemistry Letters. 21: 4528-32. PMID 21719286 DOI: 10.1016/J.Bmcl.2011.05.129 |
0.337 |
|
2011 |
Renzi F, Zhang X, Rice WJ, Torres-Arancivia C, Gomez-Llorente Y, Diaz R, Ahn K, Yu C, Li YM, Sisodia SS, Ubarretxena-Belandia I. Structure of gamma-secretase and its trimeric pre-activation intermediate by single-particle electron microscopy. The Journal of Biological Chemistry. 286: 21440-9. PMID 21454611 DOI: 10.1074/Jbc.M110.193326 |
0.463 |
|
2010 |
Ahn K, Shelton CC, Tian Y, Zhang X, Gilchrist ML, Sisodia SS, Li YM. Activation and intrinsic gamma-secretase activity of presenilin 1. Proceedings of the National Academy of Sciences of the United States of America. 107: 21435-40. PMID 21115843 DOI: 10.1073/Pnas.1013246107 |
0.511 |
|
2010 |
Kounnas MZ, Danks AM, Cheng S, Tyree C, Ackerman E, Zhang X, Ahn K, Nguyen P, Comer D, Mao L, Yu C, Pleynet D, Digregorio PJ, Velicelebi G, Stauderman KA, ... Li YM, et al. Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease. Neuron. 67: 769-80. PMID 20826309 DOI: 10.1016/J.Neuron.2010.08.018 |
0.518 |
|
2010 |
Tian Y, Crump CJ, Li YM. Dual role of alpha-secretase cleavage in the regulation of gamma-secretase activity for amyloid production. The Journal of Biological Chemistry. 285: 32549-56. PMID 20675367 DOI: 10.1074/Jbc.M110.128439 |
0.482 |
|
2010 |
Yang T, Arslanova D, Xu X, Li YM, Xia W. In vivo manifestation of Notch related phenotypes in zebrafish treated with Alzheimer's amyloid reducing gamma-secretase inhibitors. Journal of Neurochemistry. 113: 1200-9. PMID 20345767 DOI: 10.1111/j.1471-4159.2010.06681.x |
0.369 |
|
2010 |
Placanica L, Chien JW, Li YM. Characterization of an atypical gamma-secretase complex from hematopoietic origin. Biochemistry. 49: 2796-804. PMID 20178366 DOI: 10.1021/Bi901388T |
0.776 |
|
2010 |
Tian Y, Bassit B, Chau D, Li YM. An APP inhibitory domain containing the Flemish mutation residue modulates gamma-secretase activity for Abeta production. Nature Structural & Molecular Biology. 17: 151-8. PMID 20062056 DOI: 10.1038/nsmb.1743 |
0.492 |
|
2009 |
Shelton CC, Zhu L, Chau D, Yang L, Wang R, Djaballah H, Zheng H, Li YM. Modulation of gamma-secretase specificity using small molecule allosteric inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 106: 20228-33. PMID 19906985 DOI: 10.1073/Pnas.0910757106 |
0.8 |
|
2009 |
Shelton CC, Tian Y, Shum D, Radu C, Djaballah H, Li YM. A miniaturized 1536-well format gamma-secretase assay. Assay and Drug Development Technologies. 7: 461-70. PMID 19715456 DOI: 10.1089/Adt.2009.0202 |
0.503 |
|
2009 |
Shelton CC, Tian Y, Frattini MG, Li YM. An exo-cell assay for examining real-time gamma-secretase activity and inhibition. Molecular Neurodegeneration. 4: 22. PMID 19490610 DOI: 10.1186/1750-1326-4-22 |
0.388 |
|
2009 |
Placanica L, Zhu L, Li YM. Gender- and age-dependent gamma-secretase activity in mouse brain and its implication in sporadic Alzheimer disease. Plos One. 4: e5088. PMID 19352431 DOI: 10.1371/journal.pone.0005088 |
0.758 |
|
2009 |
Escobar-Alvarez S, Goldgur Y, Yang G, Ouerfelli O, Li Y, Scheinberg DA. Structure and activity of human mitochondrial peptide deformylase, a novel cancer target. Journal of Molecular Biology. 387: 1211-28. PMID 19236878 DOI: 10.1016/J.Jmb.2009.02.032 |
0.375 |
|
2009 |
Placanica L, Tarassishin L, Yang G, Peethumnongsin E, Kim SH, Zheng H, Sisodia SS, Li YM. Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes. The Journal of Biological Chemistry. 284: 2967-77. PMID 19036728 DOI: 10.1074/Jbc.M807269200 |
0.779 |
|
2008 |
Lei X, Ahn K, Zhu L, Ubarretxena-Belandia I, Li YM. Soluble oligomers of the intramembrane serine protease YqgP are catalytically active in the absence of detergents. Biochemistry. 47: 11920-9. PMID 18937501 DOI: 10.1021/Bi800385R |
0.402 |
|
2008 |
Vetrivel KS, Zhang X, Meckler X, Cheng H, Lee S, Gong P, Lopes KO, Chen Y, Iwata N, Yin KJ, Lee JM, Parent AT, Saido TC, Li YM, Sisodia SS, et al. Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta. The Journal of Biological Chemistry. 283: 19489-98. PMID 18456655 DOI: 10.1074/Jbc.M801037200 |
0.433 |
|
2007 |
Yin YI, Bassit B, Zhu L, Yang X, Wang C, Li YM. {gamma}-Secretase Substrate Concentration Modulates the Abeta42/Abeta40 Ratio: IMPLICATIONS FOR ALZHEIMER DISEASE. The Journal of Biological Chemistry. 282: 23639-44. PMID 17556361 DOI: 10.1074/Jbc.M704601200 |
0.519 |
|
2007 |
Xiong K, Clough RW, Luo XG, Struble RG, Li YM, Yan XX. [3H]-L-685,458 as a radiotracer that maps gamma-secretase complex in the rat brain: relevance to Abeta genesis and presence of active presenilin-1 components. Brain Research. 1157: 81-91. PMID 17512915 DOI: 10.1016/j.brainres.2007.04.068 |
0.331 |
|
2007 |
Antczak C, Shum D, Escobar S, Bassit B, Kim E, Seshan VE, Wu N, Yang G, Ouerfelli O, Li YM, Scheinberg DA, Djaballah H. High-throughput identification of inhibitors of human mitochondrial peptide deformylase. Journal of Biomolecular Screening. 12: 521-35. PMID 17435169 DOI: 10.1177/1087057107300463 |
0.329 |
|
2007 |
Vetrivel KS, Gong P, Bowen JW, Cheng H, Chen Y, Carter M, Nguyen PD, Placanica L, Wieland FT, Li YM, Kounnas MZ, Thinakaran G. Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism. Molecular Neurodegeneration. 2: 4. PMID 17288597 DOI: 10.1186/1750-1326-2-4 |
0.765 |
|
2006 |
Deng Y, Tarassishin L, Kallhoff V, Peethumnongsin E, Wu L, Li YM, Zheng H. Deletion of presenilin 1 hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3845-54. PMID 16597739 DOI: 10.1523/Jneurosci.5384-05.2006 |
0.546 |
|
2006 |
Lai MT, Crouthamel MC, DiMuzio J, Pietrak BL, Donoviel DB, Bernstein A, Gardell SJ, Li YM, Hazuda D. A presenilin-independent aspartyl protease prefers the gamma-42 site cleavage. Journal of Neurochemistry. 96: 118-25. PMID 16300640 DOI: 10.1111/J.1471-4159.2005.03528.X |
0.461 |
|
2004 |
Tarassishin L, Yin YI, Bassit B, Li YM. Processing of Notch and amyloid precursor protein by gamma-secretase is spatially distinct. Proceedings of the National Academy of Sciences of the United States of America. 101: 17050-5. PMID 15563588 DOI: 10.1073/Pnas.0408007101 |
0.539 |
|
2004 |
Kim SH, Yin YI, Li YM, Sisodia SS. Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway. The Journal of Biological Chemistry. 279: 48615-9. PMID 15456788 DOI: 10.1074/Jbc.C400396200 |
0.509 |
|
2004 |
Wang H, Luo WJ, Zhang YW, Li YM, Thinakaran G, Greengard P, Xu H. Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components. The Journal of Biological Chemistry. 279: 40560-6. PMID 15247291 DOI: 10.1074/Jbc.M404345200 |
0.515 |
|
2004 |
Li Y, Tarassishin L, Yin Y, Bassit B. O2-03-06 Mechanism of gamma-secretase mediated APP and notch processing Neurobiology of Aging. 25: S37-S38. DOI: 10.1016/S0197-4580(04)80124-6 |
0.351 |
|
2003 |
Lee MD, Antczak C, Li Y, Sirotnak FM, Bornmann WG, Scheinberg DA. A new human peptide deformylase inhibitable by actinonin. Biochemical and Biophysical Research Communications. 312: 309-15. PMID 14637138 DOI: 10.1016/J.Bbrc.2003.10.123 |
0.352 |
|
2003 |
Schroeter EH, Ilagan MX, Brunkan AL, Hecimovic S, Li YM, Xu M, Lewis HD, Saxena MT, De Strooper B, Coonrod A, Tomita T, Iwatsubo T, Moore CL, Goate A, Wolfe MS, et al. A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 100: 13075-80. PMID 14566063 DOI: 10.1073/Pnas.1735338100 |
0.532 |
|
2003 |
Netzer WJ, Dou F, Cai D, Veach D, Jean S, Li Y, Bornmann WG, Clarkson B, Xu H, Greengard P. Gleevec inhibits beta-amyloid production but not Notch cleavage. Proceedings of the National Academy of Sciences of the United States of America. 100: 12444-9. PMID 14523244 DOI: 10.1073/Pnas.1534745100 |
0.506 |
|
2003 |
Beher D, Fricker M, Nadin A, Clarke EE, Wrigley JD, Li YM, Culvenor JG, Masters CL, Harrison T, Shearman MS. In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand. Biochemistry. 42: 8133-42. PMID 12846562 DOI: 10.1021/Bi034045Z |
0.461 |
|
2003 |
Lai MT, Chen E, Crouthamel MC, DiMuzio-Mower J, Xu M, Huang Q, Price E, Register RB, Shi XP, Donoviel DB, Bernstein A, Hazuda D, Gardell SJ, Li YM. Presenilin-1 and presenilin-2 exhibit distinct yet overlapping gamma-secretase activities. The Journal of Biological Chemistry. 278: 22475-81. PMID 12684521 DOI: 10.1074/Jbc.M300974200 |
0.407 |
|
2002 |
Xu M, Lai MT, Huang Q, DiMuzio-Mower J, Castro JL, Harrison T, Nadin A, Neduvelil JG, Shearman MS, Shafer JA, Gardell SJ, Li YM. gamma-Secretase: characterization and implication for Alzheimer disease therapy. Neurobiology of Aging. 23: 1023-30. PMID 12470798 |
0.526 |
|
2002 |
Figueroa DJ, Morris JA, Ma L, Kandpal G, Chen E, Li YM, Austin CP. Presenilin-dependent gamma-secretase activity modulates neurite outgrowth. Neurobiology of Disease. 9: 49-60. PMID 11848684 DOI: 10.1006/nbdi.2001.0447 |
0.442 |
|
2000 |
Beher D, Li Y, Gardell SJ, Shearman MS. Direct analysis of γ-secretase activity in SH-SY5Y neuroblastoma cells identifies the Golgi as the main compartment of amyloid-β(X-40) peptide. Generation Neurobiology of Aging. 21: 187. DOI: 10.1016/S0197-4580(00)82183-1 |
0.379 |
|
Low-probability matches (unlikely to be authored by this person) |
2022 |
Antman-Passig M, Wong E, Frost GR, Cupo C, Shah J, Agustinus A, Chen Z, Mancinelli C, Kamel M, Li T, Jonas LA, Li YM, Heller DA. Optical Nanosensor for Intracellular and Intracranial Detection of Amyloid-Beta. Acs Nano. PMID 35420796 DOI: 10.1021/acsnano.2c00054 |
0.296 |
|
2022 |
Alexander C, Li T, Hattori Y, Chiu D, Frost GR, Jonas L, Liu C, Anderson CJ, Wong E, Park L, Iadecola C, Li YM. Hypoxia Inducible Factor-1α binds and activates γ-secretase for Aβ production under hypoxia and cerebral hypoperfusion. Molecular Psychiatry. PMID 35764706 DOI: 10.1038/s41380-022-01676-7 |
0.295 |
|
2006 |
Weng AP, Millholland JM, Yashiro-Ohtani Y, Arcangeli ML, Lau A, Wai C, Del Bianco C, Rodriguez CG, Sai H, Tobias J, Li Y, Wolfe MS, Shachaf C, Felsher D, Blacklow SC, et al. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes & Development. 20: 2096-109. PMID 16847353 DOI: 10.1101/Gad.1450406 |
0.295 |
|
2017 |
Fried ES, Li YM, Gilchrist ML. Phase Composition Control in Microsphere-Supported Biomembrane Systems. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 28198634 DOI: 10.1021/Acs.Langmuir.6B04150 |
0.292 |
|
2019 |
Frost GR, Jonas LA, Li YM. Friend, Foe or Both? Immune Activity in Alzheimer's Disease. Frontiers in Aging Neuroscience. 11: 337. PMID 31920620 DOI: 10.3389/fnagi.2019.00337 |
0.286 |
|
2009 |
Yang G, Yin YI, Chun J, Shelton CC, Ouerfelli O, Li YM. Stereo-controlled synthesis of novel photoreactive gamma-secretase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 922-5. PMID 19097779 DOI: 10.1016/j.bmcl.2008.11.117 |
0.267 |
|
2010 |
Liu H, Chi AW, Arnett KL, Chiang MY, Xu L, Shestova O, Wang H, Li YM, Bhandoola A, Aster JC, Blacklow SC, Pear WS. Notch dimerization is required for leukemogenesis and T-cell development. Genes & Development. 24: 2395-407. PMID 20935071 DOI: 10.1101/Gad.1975210 |
0.265 |
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2020 |
Barros M, Houlihan WJ, Paresi CJ, Brendel M, Rynearson K, Lee CW, Prikhodko O, Cregger C, Chang G, Wagner SL, Gilchrist ML, Li Y. γ-Secretase Partitioning into Lipid Bilayers Remodels Membrane Microdomains after Direct Insertion. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 32432881 DOI: 10.1021/Acs.Langmuir.0C01178 |
0.264 |
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2022 |
Jonas LA, Jain T, Li YM. Functional insight into LOAD-associated microglial response genes. Open Biology. 12: 210280. PMID 35078351 DOI: 10.1098/rsob.210280 |
0.262 |
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2004 |
Coburn CA, Stachel SJ, Li YM, Rush DM, Steele TG, Chen-Dodson E, Holloway MK, Xu M, Huang Q, Lai MT, DiMuzio J, Crouthamel MC, Shi XP, Sardana V, Chen Z, et al. Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases. Journal of Medicinal Chemistry. 47: 6117-9. PMID 15566281 DOI: 10.1021/jm049388p |
0.262 |
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2004 |
Chun J, Yin YI, Yang G, Tarassishin L, Li YM. Stereoselective synthesis of photoreactive peptidomimetic gamma-secretase inhibitors. The Journal of Organic Chemistry. 69: 7344-7. PMID 15471490 DOI: 10.1021/jo0486948 |
0.253 |
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2009 |
Lei X, Li YM. The processing of human rhomboid intramembrane serine protease RHBDL2 is required for its proteolytic activity. Journal of Molecular Biology. 394: 815-25. PMID 19850051 DOI: 10.1016/j.jmb.2009.10.025 |
0.247 |
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2009 |
Meng RD, Shelton CC, Li YM, Qin LX, Notterman D, Paty PB, Schwartz GK. gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity. Cancer Research. 69: 573-82. PMID 19147571 DOI: 10.1158/0008-5472.CAN-08-2088 |
0.246 |
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2021 |
Nie P, Kalidindi T, Nagle VL, Wu X, Li T, Liao GP, Frost G, Henry KE, Punzalan B, Carter LM, Lewis JS, Pillarsetty NVK, Li YM. Imaging of Cancer γ-Secretase Activity Using an Inhibitor-based PET Probe. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34475100 DOI: 10.1158/1078-0432.CCR-21-0940 |
0.239 |
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2022 |
Yang L, Ball A, Liu J, Jain T, Li YM, Akhter F, Zhu D, Wang J. Cyclic microchip assay for measurement of hundreds of functional proteins in single neurons. Nature Communications. 13: 3548. PMID 35729174 DOI: 10.1038/s41467-022-31336-x |
0.232 |
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2020 |
Liu H, Mei FC, Yang W, Wang H, Wong E, Cai J, Toth E, Luo P, Li YM, Zhang W, Cheng X. Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling. Science Advances. 6: eaay3566. PMID 31911948 DOI: 10.1126/sciadv.aay3566 |
0.225 |
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2016 |
Paresi CJ, Liu Q, Li YM. Benzimidazole covalent probes and the gastric H(+)/K(+)-ATPase as a model system for protein labeling in a copper-free setting. Molecular Biosystems. PMID 26952080 DOI: 10.1039/c6mb00024j |
0.211 |
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2014 |
Creech GS, Paresi C, Li YM, Danishefsky SJ. Chemical synthesis of the ATAD2 bromodomain. Proceedings of the National Academy of Sciences of the United States of America. 111: 2891-6. PMID 24516155 DOI: 10.1073/Pnas.1400556111 |
0.199 |
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2009 |
Mullendore ME, Koorstra JB, Li YM, Offerhaus GJ, Fan X, Henderson CM, Matsui W, Eberhart CG, Maitra A, Feldmann G. Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2291-301. PMID 19258443 DOI: 10.1158/1078-0432.Ccr-08-2004 |
0.194 |
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2023 |
Liu C, Nikain C, Li YM. γ-Secretase fanning the fire of innate immunity. Biochemical Society Transactions. PMID 37449907 DOI: 10.1042/BST20221445 |
0.186 |
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2022 |
Kleffman K, Levinson G, Rose IVL, Blumenberg LM, Shadaloey SAA, Dhabaria A, Wong E, Galan-Echevarria F, Karz A, Argibay D, Von Itter R, Floristan A, Baptiste G, Eskow NM, Tranos JA, ... ... Li YM, et al. Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis. Cancer Discovery. PMID 35262173 DOI: 10.1158/2159-8290.CD-21-1006 |
0.179 |
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2020 |
Mao LF, Wang YW, Zhao J, Xu GQ, Yao XJ, Li YM. Discovery of Icotinib-1,2,3-Triazole Derivatives as IDO1 Inhibitors. Frontiers in Pharmacology. 11: 579024. PMID 33101032 DOI: 10.3389/fphar.2020.579024 |
0.178 |
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2020 |
Frost GR, Longo V, Li T, Jonas LA, Judenhofer M, Cherry S, Koutcher J, Lekaye C, Zanzonico P, Li YM. Author Correction: Hybrid PET/MRI enables high-spatial resolution, quantitative imaging of amyloid plaques in an Alzheimer's disease mouse model. Scientific Reports. 10: 13826. PMID 32778663 DOI: 10.1038/S41598-020-70134-7 |
0.174 |
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2008 |
Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L. Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Cell Stem Cell. 2: 461-71. PMID 18462696 DOI: 10.1016/J.Stem.2008.03.001 |
0.166 |
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2020 |
Frost GR, Longo V, Li T, Jonas LA, Judenhofer M, Cherry S, Koutcher J, Lekaye C, Zanzonico P, Li YM. Hybrid PET/MRI enables high-spatial resolution, quantitative imaging of amyloid plaques in an Alzheimer's disease mouse model. Scientific Reports. 10: 10379. PMID 32587315 DOI: 10.1038/S41598-020-67284-Z |
0.165 |
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2007 |
Gao Z, Tian Y, Wang J, Yin Q, Wu H, Li YM, Jiang X. A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo. The Journal of Biological Chemistry. 282: 30718-27. PMID 17724022 DOI: 10.1074/Jbc.M705258200 |
0.158 |
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2006 |
Fan X, Matsui W, Khaki L, Stearns D, Chun J, Li YM, Eberhart CG. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Research. 66: 7445-52. PMID 16885340 DOI: 10.1158/0008-5472.Can-06-0858 |
0.15 |
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2010 |
Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells (Dayton, Ohio). 28: 5-16. PMID 19904829 DOI: 10.1002/Stem.254 |
0.144 |
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2003 |
Cai YP, Su CY, Chen CL, Li YM, Kang BS, Chan AS, Kaim W. Formation of racemate and mesocate complexes from an achiral tripodal ligand containing three benzimidazole groups. Inorganic Chemistry. 42: 163-8. PMID 12513091 DOI: 10.1021/Ic025934Y |
0.144 |
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2005 |
Yun H, Chou TC, Dong H, Tian Y, Li YM, Danishefsky SJ. Total synthesis as a resource in drug discovery: the first in vivo evaluation of panaxytriol and its derivatives. The Journal of Organic Chemistry. 70: 10375-80. PMID 16323847 DOI: 10.1021/Jo0515475 |
0.135 |
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2022 |
Chen X, Mao LF, Tian S, Tian X, Meng X, Wang MK, Xu W, Li YM, Liu K, Dong Z. Icotinib derivatives as tyrosine kinase inhibitors with anti-esophageal squamous carcinoma activity. Frontiers in Pharmacology. 13: 1028692. PMID 36467103 DOI: 10.3389/fphar.2022.1028692 |
0.134 |
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2004 |
Huang ZS, Wu HQ, Duan ZF, Xie BF, Liu ZC, Feng GK, Gu LQ, Chan AS, Li YM. Synthesis and cytotoxicity study of alkannin derivatives. European Journal of Medicinal Chemistry. 39: 755-64. PMID 15337288 DOI: 10.1016/J.Ejmech.2004.05.004 |
0.126 |
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2013 |
Gao F, Li YM, Hong GL, Xu ZF, Liu QC, He QL, Lin LQ, Weng SH. PRSS1_p.Leu81Met mutation results in autoimmune pancreatitis. World Journal of Gastroenterology : Wjg. 19: 3332-8. PMID 23745036 DOI: 10.3748/wjg.v19.i21.3332 |
0.124 |
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2005 |
Zhou JL, Lu YJ, Ou TM, Zhou JM, Huang ZS, Zhu XF, Du CJ, Bu XZ, Ma L, Gu LQ, Li YM, Chan AS. Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase. Journal of Medicinal Chemistry. 48: 7315-21. PMID 16279791 DOI: 10.1021/jm050041b |
0.12 |
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2023 |
Kim M, Chen C, Yaari Z, Frederiksen R, Randall E, Wollowitz J, Cupo C, Wu X, Shah J, Worroll D, Lagenbacher RE, Goerzen D, Li YM, An H, Wang Y, et al. Nanosensor-based monitoring of autophagy-associated lysosomal acidification in vivo. Nature Chemical Biology. PMID 37322156 DOI: 10.1038/s41589-023-01364-9 |
0.119 |
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2020 |
Wang WJ, Mao LF, Lai HL, Wang YW, Jiang ZB, Li W, Huang JM, Xie YJ, Xu C, Liu P, Li YM, Leung ELH, Yao XJ. Dolutegravir derivative inhibits proliferation and induces apoptosis of non-small cell lung cancer cells via calcium signaling pathway. Pharmacological Research. 105129. PMID 32783976 DOI: 10.1016/j.phrs.2020.105129 |
0.119 |
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2005 |
Hua Z, Carcache DA, Tian Y, Li YM, Danishefsky SJ. The synthesis and preliminary biological evaluation of a novel steroid with neurotrophic activity: NGA0187. The Journal of Organic Chemistry. 70: 9849-56. PMID 16292815 DOI: 10.1021/Jo051556D |
0.116 |
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2004 |
Cho YS, Carcache DA, Tian Y, Li YM, Danishefsky SJ. Total synthesis of (+/-)-jiadifenin, a non-peptidyl neurotrophic modulator. Journal of the American Chemical Society. 126: 14358-9. PMID 15521747 DOI: 10.1021/ja045939p |
0.111 |
|
2023 |
Jain T, Li YM. Gut microbes modulate neurodegeneration. Science (New York, N.Y.). 379: 142-143. PMID 36634183 DOI: 10.1126/science.adf9548 |
0.107 |
|
2005 |
Shen Q, Peng Q, Shao J, Liu X, Huang Z, Pu X, Ma L, Li YM, Chan AS, Gu L. Synthesis and biological evaluation of functionalized coumarins as acetylcholinesterase inhibitors. European Journal of Medicinal Chemistry. 40: 1307-15. PMID 16182411 DOI: 10.1016/j.ejmech.2005.07.014 |
0.102 |
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2023 |
Yu S, Cai Q, Li J, Yu T, Liang J, Jiao Z, Yao C, Li YM. Enantioselective Michael addition of malonates to β,γ-unsaturated α-ketoesters catalysed by Cu(II) complexes bearing binaphthyl-proline hybrid ligands. Organic & Biomolecular Chemistry. 21: 1764-1770. PMID 36723244 DOI: 10.1039/d2ob02305a |
0.1 |
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2020 |
Mao L, Sun G, Zhao J, Xu G, Yuan M, Li YM. Design, synthesis and antitumor activity of icotinib derivatives. Bioorganic Chemistry. 105: 104421. PMID 33181408 DOI: 10.1016/j.bioorg.2020.104421 |
0.099 |
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2004 |
Yi B, Fan QH, Deng GJ, Li YM, Qiu LQ, Chan AS. Novel chiral dendritic diphosphine ligands for Rh(I)-catalyzed asymmetric hydrogenation: remarkable structural effects on catalytic properties. Organic Letters. 6: 1361-4. PMID 15101742 DOI: 10.1021/Ol036512A |
0.096 |
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2023 |
Yu S, Cai Q, Yu T, Li J, Yao C, Li YM. New Binaphthyl-Proline-Based Chiral Ligands Bearing Imidazoline Groups: Design, Synthesis, and Their Application in Enantioselective Conjugate Addition of 4-Hydroxycoumarin and Related Nucleophiles to β,γ-Unsaturated α-Ketoesters. The Journal of Organic Chemistry. PMID 37874252 DOI: 10.1021/acs.joc.3c01262 |
0.095 |
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2022 |
Mao LF, Wang ZZ, Wu Q, Chen X, Yang JX, Wang X, Li YM. Design, Synthesis, and Antitumor Activity of Erlotinib Derivatives. Frontiers in Pharmacology. 13: 849364. PMID 35517789 DOI: 10.3389/fphar.2022.849364 |
0.093 |
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2005 |
Waters SP, Tian Y, Li YM, Danishefsky SJ. Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production. Journal of the American Chemical Society. 127: 13514-5. PMID 16190712 DOI: 10.1021/ja055220x |
0.09 |
|
2006 |
Qiu L, Kwong FY, Wu J, Lam WH, Chan S, Yu WY, Li YM, Guo R, Zhou Z, Chan AS. A new class of versatile chiral-bridged atropisomeric diphosphine ligands: remarkably efficient ligand syntheses and their applications in highly enantioselective hydrogenation reactions. Journal of the American Chemical Society. 128: 5955-65. PMID 16637664 DOI: 10.1021/Ja0602694 |
0.086 |
|
2006 |
Carcache DA, Cho YS, Hua Z, Tian Y, Li YM, Danishefsky SJ. Total synthesis of (+/-)-jiadifenin and studies directed to understanding its SAR: probing mechanistic and stereochemical issues in palladium-mediated allylation of enolate-like structures. Journal of the American Chemical Society. 128: 1016-22. PMID 16417394 DOI: 10.1021/Ja056980A |
0.085 |
|
2019 |
Lu XY, Li JS, Wang SQ, Zhu YJ, Li YM, Yan LY, Li JM, Wang JY, Zhou HP, Ge XT. Pd-Catalyzed decarboxylative cross-coupling reactions of epoxides with α,β-unsaturated carboxylic acids. Chemical Communications (Cambridge, England). PMID 31463500 DOI: 10.1039/c9cc04795f |
0.081 |
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2023 |
Yu S, Cai Q, Wang C, Hou J, Liang J, Jiao Z, Yao C, Li YM. Enantioselective Friedel-Crafts Alkylation of Indoles with β,γ-Unsaturated α-Ketoesters Catalyzed by New Copper(I) Catalysts. The Journal of Organic Chemistry. PMID 36791262 DOI: 10.1021/acs.joc.2c02749 |
0.077 |
|
2014 |
Liu GQ, Li YM. Regioselective (diacetoxyiodo)benzene-promoted halocyclization of unfunctionalized olefins. The Journal of Organic Chemistry. 79: 10094-109. PMID 25310379 DOI: 10.1021/jo501739j |
0.073 |
|
2018 |
Cui B, Sun H, Xu Y, Li L, Duan L, Li YM. Mn(OAc)3-Mediated Hydrotrifluoromethylation of Unactivated Alkenes Using CF3SO2Na as the Trifluoromethyl Source. The Journal of Organic Chemistry. PMID 29733609 DOI: 10.1021/acs.joc.8b00633 |
0.072 |
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2020 |
Yang CH, Han M, Li W, Zhu N, Sun Z, Wang J, Yang Z, Li YM. Direct Intramolecular Aminoboration of Allenes. Organic Letters. PMID 32551686 DOI: 10.1021/acs.orglett.0c01685 |
0.071 |
|
2005 |
Kwong FY, Li YM, Lam WH, Qiu L, Lee HW, Yeung CH, Chan KS, Chan AS. Rhodium-catalyzed asymmetric aqueous Pauson-Khand-type reaction. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 3872-80. PMID 15827980 DOI: 10.1002/CHEM.200401237 |
0.067 |
|
2019 |
Huang HY, Lin YC, Li J, Huang KY, Shrestha S, Hong HC, Tang Y, Chen YG, Jin CN, Yu Y, Xu JT, Li YM, Cai XX, Zhou ZY, Chen XH, et al. miRTarBase 2020: updates to the experimentally validated microRNA-target interaction database. Nucleic Acids Research. PMID 31647101 DOI: 10.1093/nar/gkz896 |
0.061 |
|
2008 |
Dong ZZ, Yao DF, Yu HB, Gu WJ, Shen YC, Li YM, Wang YL, Shen JJ. [Dynamic expression and quantitative analysis of hepatic nuclear factor-kappa B and its gene during the development of hepatocellular carcinoma]. Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology. 16: 669-73. PMID 18822207 |
0.059 |
|
2010 |
Sha JM, Yan ZY, Cheng GC, Weil XY, Tao YQ, Li YM, Luo L. In-vitro seeding of human umbilical cord vein endothelial cells on hydroxyapatite for mechanical heart valve applications. The Journal of Heart Valve Disease. 19: 506-12. PMID 20845900 |
0.059 |
|
2015 |
Yang CH, Zhang YS, Fan WW, Liu GQ, Li YM. Intramolecular Aminoboration of Unfunctionalized Olefins. Angewandte Chemie (International Ed. in English). 54: 12636-9. PMID 26331979 DOI: 10.1002/anie.201505489 |
0.057 |
|
2019 |
Xu ZQ, Wang WB, Zheng LC, Li L, Duan L, Li YM. Iodine-mediated aminosulfonylation of alkenyl sulfonamides with sulfonyl hydrazides: synthesis of sulfonylmethyl piperidines, pyrrolidines and pyrazolines. Organic & Biomolecular Chemistry. PMID 31577324 DOI: 10.1039/c9ob01847f |
0.055 |
|
2016 |
Liu GQ, Cui B, Xu R, Li YM. Preparation of trans-2-substituted-4-halopiperidines and cis-2-substituted-4-halotetrahydropyrans via AlCl3-catalyzed Prins reaction. The Journal of Organic Chemistry. PMID 27214117 DOI: 10.1021/acs.joc.6b00725 |
0.054 |
|
2006 |
Lu G, Kwong FY, Ruan JW, Li YM, Chan AS. Highly enantioselective addition of in situ prepared arylzinc to aldehydes catalyzed by a series of atropisomeric binaphthyl-derived amino alcohols. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 4115-20. PMID 16555357 DOI: 10.1002/Chem.200501048 |
0.053 |
|
2009 |
Wu W, Yao DF, Qiu LW, Sai WL, Shen JJ, Yu HB, Wu XH, Li YM, Wang YL, Gu WJ. Characteristics of hepatic nuclear-transcription factor-kappa B expression and quantitative analysis in rat hepatocarcinogenesis. Hepatobiliary & Pancreatic Diseases International : Hbpd Int. 8: 504-9. PMID 19822494 |
0.052 |
|
2022 |
Yao C, Chen Y, Wang C, Sun R, Chang H, Jiang R, Li L, Wang X, Li YM. Binaphthyl-Proline Hybrid Chiral Ligands: Modular Design, Synthesis, and Enantioswitching in Cu(II)-Catalyzed Enantioselective Henry Reactions. The Journal of Organic Chemistry. PMID 36106472 DOI: 10.1021/acs.joc.2c01127 |
0.051 |
|
2004 |
Zhang SL, Huang ZS, An LK, Bu XZ, Ma L, Li YM, Chan AS, Gu LQ. Synthesis of zwitterionic 4-hydroxycoumarin derivatives through a unique reaction of 4-hydroxycoumarins with p- benzoquinone and pyridine. Organic Letters. 6: 4853-5. PMID 15606083 DOI: 10.1021/ol048109p |
0.051 |
|
2022 |
Li WH, Li YM, Yang JL, Wu XL. An integrated design of electrodes for flexible dual-ion batteries. Chemsuschem. PMID 35861451 DOI: 10.1002/cssc.202201252 |
0.051 |
|
2009 |
Yao DF, Jiang H, Yao M, Li YM, Gu WJ, Shen YC, Qiu LW, Wu W, Wu XH, Sai WL. Quantitative analysis of hepatic hypoxia-inducible factor-1alpha and its abnormal gene expression during the formation of hepatocellular carcinoma. Hepatobiliary & Pancreatic Diseases International : Hbpd Int. 8: 407-13. PMID 19666411 |
0.049 |
|
2020 |
Yao C, Wu P, Huang Y, Chen Y, Li L, Li YM. Binaphthyl-based chiral ligands: design, synthesis and evaluation of their performance in enantioselective addition of diethylzinc to aromatic aldehydes. Organic & Biomolecular Chemistry. PMID 33237100 DOI: 10.1039/d0ob02127j |
0.047 |
|
2015 |
Liu GQ, Yang CH, Li YM. Modular preparation of 5-halomethyl-2-oxazolines via PhI(OAc)2-promoted intramolecular halooxygenation of N-allylcarboxamides. The Journal of Organic Chemistry. PMID 26501791 DOI: 10.1021/acs.joc.5b01832 |
0.046 |
|
2017 |
Sun H, Cui B, Duan L, Li YM. Intramolecular Aminoalkoxylation of Unfunctionalized Olefins via Intramolecular Iodoamination and Aziridinium Ion Ring-Opening Sequence. Organic Letters. PMID 28333470 DOI: 10.1021/acs.orglett.7b00284 |
0.043 |
|
2019 |
Xu ZQ, Zheng LC, Li L, Duan L, Li YM. Metal-free oxysulfonylation and aminosulfonylation of alkenyl oximes: synthesis of sulfonylated isoxazolines and cyclic nitrones. Organic & Biomolecular Chemistry. PMID 30629072 DOI: 10.1039/c8ob02879f |
0.04 |
|
2011 |
Li YM, Li JY, Wang Q, Hao AY, Sun T. (Z)-N-{3-[(2-Chloro-1,3-thia-zol-5-yl)meth-yl]-1,3-thia-zolidin-2-yl-idene}cyanamide. Acta Crystallographica. Section E, Structure Reports Online. 67: o3303. PMID 22199805 DOI: 10.1107/S1600536811047404 |
0.038 |
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2018 |
Xu ZQ, Wang C, Li L, Duan L, Li YM. Construction of 3,4-Dihydroisoquinolinones and Indanones via DTBP-Promoted Oxidative Coupling of N-Allylbenzamides with Aromatic Aldehydes. The Journal of Organic Chemistry. PMID 30106573 DOI: 10.1021/acs.joc.8b01242 |
0.036 |
|
2023 |
Xue L, Hou J, Li J, Yu T, Cai Q, Yu S, Yao C, Li YM. Copper(II)-Catalyzed Enantioselective Aza-Friedel-Crafts Reaction of Indoles with Isatin-Derived -Boc-Ketimines. The Journal of Organic Chemistry. 88: 14345-14350. PMID 37791977 DOI: 10.1021/acs.joc.3c01144 |
0.035 |
|
2022 |
Li YM, Li WH, Diao WY, Tao FY, Wu XL, Zhang XY, Zhang JP. Uniform Zn Flux Distribution Achieved by an Artificial Three-Dimensional Framework: The Enhanced Ion-Transfer Kinetics for Long-Life and Dendrite-Free Zn Anodes. Acs Applied Materials & Interfaces. PMID 35544741 DOI: 10.1021/acsami.2c04888 |
0.034 |
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2023 |
Hou J, Xue L, Yu T, Li J, Yu S, Yao C, Li YM. Zn(II)-catalysed enantioselective addition of alcohols and -butyl hydroperoxide to isatin-derived -Boc ketimines. Chemical Communications (Cambridge, England). PMID 37218456 DOI: 10.1039/d3cc01527k |
0.033 |
|
2021 |
Yao C, Chen Y, Sun R, Wang C, Huang Y, Li L, Li YM. Binaphthyl-prolinol chiral ligands: design and their application in enantioselective arylation of aromatic aldehydes. Organic & Biomolecular Chemistry. 19: 3644-3655. PMID 33908558 DOI: 10.1039/d1ob00289a |
0.03 |
|
2022 |
Li YM, Zhu YM, Gao LM, Han ZW, Chen XJ, Yan C, Ye RP, Cao DR. Radiomic analysis based on multi-phase magnetic resonance imaging to predict preoperatively microvascular invasion in hepatocellular carcinoma. World Journal of Gastroenterology. 28: 2733-2747. PMID 35979164 DOI: 10.3748/wjg.v28.i24.2733 |
0.029 |
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2018 |
Lu XY, Li JS, Wang JY, Wang SQ, Li YM, Zhu YJ, Zhou R, Ma WJ. Cu-catalyzed cross-coupling reactions of vinyl epoxide with organoboron compounds: access to homoallylic alcohols. Rsc Advances. 8: 41561-41565. PMID 35559282 DOI: 10.1039/c8ra09048c |
0.025 |
|
2010 |
Dong ZZ, Yao DF, Li SS, Li YM, Tai BJ, Qiu LW, Wu W, Yao NH, Sai WL. [Expression characteristics of hypoxia inducible factor-1a and its clinical values in hepatocellular carcinoma]. Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology. 18: 506-10. PMID 20678440 DOI: 10.3760/cma.j.issn.1007-3418.2010.07.009 |
0.019 |
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2022 |
Ma SY, Gong YQ, Zhang WJ, Liang BH, Li YM, Xie ZM, Zhu HL. Split-face comparison of the efficacy of picosecond 532 nm Nd:YAG laser and Q-switched 755 nm Alexandrite laser for treatment of freckles. Journal of Cosmetic and Laser Therapy : Official Publication of the European Society For Laser Dermatology. 1-6. PMID 35400288 DOI: 10.1080/14764172.2022.2049311 |
0.012 |
|
2002 |
Fan QH, Li YM, Chan AS. Recoverable catalysts for asymmetric organic synthesis. Chemical Reviews. 102: 3385-466. PMID 12371889 DOI: 10.1021/Cr010341A |
0.01 |
|
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