Year |
Citation |
Score |
2024 |
Zeller SL, Spirollari E, Dicpinigaitis AJ, Wainwright JV, Hanft SJ, Gandhi CD, Jhanwar-Uniyal M. Brain Metastases Are Regulated by Immuno-inflammatory Signaling Pathways Governed by STAT3, MAPK and Tumor Suppressor p53 Status: Possible Therapeutic Targets. Anticancer Research. 44: 13-22. PMID 38160007 DOI: 10.21873/anticanres.16783 |
0.373 |
|
2023 |
Machova Urdzikova L, Cimermanova V, Karova K, Dominguez J, Stepankova K, Petrovicova M, Havelikova K, D Gandhi C, Jhanwar-Uniyal M, Jendelova P. The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury. Antioxidants (Basel, Switzerland). 12. PMID 36829922 DOI: 10.3390/antiox12020363 |
0.35 |
|
2022 |
Jhanwar-Uniyal M, Gellerson O, Bree J, Das M, Kleinman G, Gandhi CD. Defining the role of mTOR pathway in the regulation of stem cells of glioblastoma. Advances in Biological Regulation. 100946. PMID 36658088 DOI: 10.1016/j.jbior.2022.100946 |
0.524 |
|
2021 |
Jhanwar-Uniyal M, Dominguez JF, Mohan AL, Tobias ME, Gandhi CD. Disentangling the signaling pathways of mTOR complexes, mTORC1 and mTORC2, as a therapeutic target in glioblastoma. Advances in Biological Regulation. 83: 100854. PMID 34996736 DOI: 10.1016/j.jbior.2021.100854 |
0.449 |
|
2021 |
Amin AG, Jeong SW, Gillick JL, Sursal T, Murali R, Gandhi CD, Jhanwar-Uniyal M. Targeting the mTOR pathway using novel ATP‑competitive inhibitors, Torin1, Torin2 and XL388, in the treatment of glioblastoma. International Journal of Oncology. 59. PMID 34523696 DOI: 10.3892/ijo.2021.5263 |
0.471 |
|
2021 |
Vargova I, Machova Urdzikova L, Karova K, Smejkalova B, Sursal T, Cimermanova V, Turnovcova K, Gandhi CD, Jhanwar-Uniyal M, Jendelova P. Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response. Biomedicines. 9. PMID 34073791 DOI: 10.3390/biomedicines9060593 |
0.342 |
|
2019 |
Jhanwar-Uniyal M, Wainwright JV, Mohan AL, Tobias ME, Murali R, Gandhi CD, Schmidt MH. Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship. Advances in Biological Regulation. PMID 31010692 DOI: 10.1016/J.Jbior.2019.03.003 |
0.541 |
|
2019 |
Karova K, Wainwright JV, Machova-Urdzikova L, Pisal RV, Schmidt M, Jendelova P, Jhanwar-Uniyal M. Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition. Journal of Neuroinflammation. 16: 12. PMID 30654804 DOI: 10.1186/S12974-019-1394-7 |
0.374 |
|
2019 |
Wainwright JV, Cooper JB, Chandy A, Gandhi CD, Schmidt MH, Jhanwar-Uniyal M. Abstract 158: Mutantp53, MAPK and STAT3 promote metastasis to the brain: Demonstrated by protein, gene, and functional analysis Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-158 |
0.32 |
|
2018 |
Ruzicka J, Urdzikova LM, Kloudova A, Amin AG, Vallova J, Kubinova S, Schmidt MH, Jhanwar-Uniyal M, Jendelova P. Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats. Acta Neurobiologiae Experimentalis. 78: 358-374. PMID 30624435 DOI: 10.21307/Ane-2018-035 |
0.357 |
|
2018 |
Cooper JB, Ronecker JS, Tobias ME, Mohan AL, Hillard V, Murali R, Gandhi CD, Schmidt MH, Jhanwar-Uniyal M. Molecular Sequence of Events and Signaling Pathways in Cerebral Metastases. Anticancer Research. 38: 1859-1877. PMID 29599302 DOI: 10.21873/Anticanres.12424 |
0.391 |
|
2018 |
Ruzicka J, Urdzikova LM, Svobodova B, Amin AG, Karova K, Dubisova J, Zaviskova K, Kubinova S, Schmidt M, Jhanwar-Uniyal M, Jendelova P. Does combined therapy of curcumin and epigallocatechin gallate have a synergistic neuroprotective effect against spinal cord injury? Neural Regeneration Research. 13: 119-127. PMID 29451216 DOI: 10.4103/1673-5374.224379 |
0.33 |
|
2017 |
Machova Urdzikova L, Ruzicka J, Karova K, Kloudova A, Svobodova B, Amin A, Dubisova J, Schmidt M, Kubinova S, Jhanwar-Uniyal M, Jendelova P. A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines. Neuropharmacology. PMID 28899730 DOI: 10.1016/J.Neuropharm.2017.09.006 |
0.322 |
|
2017 |
Jhanwar-Uniyal M, Amin AG, Cooper JB, Das K, Schmidt MH, Murali R. Discrete signaling mechanisms of mTORC1 and mTORC2: Connected yet apart in cellular and molecular aspects. Advances in Biological Regulation. PMID 28189457 DOI: 10.1016/J.Jbior.2016.12.001 |
0.542 |
|
2017 |
Amin AG, Wang A, Braun A, Tobias M, Murali R, Jhanwar-Uniyal M. Abstract 3125: Therapeutic implications of mTORC1 and mTORC2 inhibitors in genetically heterogeneous glioblastoma Cancer Research. 77: 3125-3125. DOI: 10.1158/1538-7445.Am2017-3125 |
0.544 |
|
2016 |
Ruzicka J, Machova-Urdzikova L, Gillick J, Amemori T, Romanyuk N, Karova K, Zaviskova K, Dubisova J, Kubinova S, Murali R, Sykova E, Jhanwar-Uniyal M, Jendelova P. A comparative study of three different types of stem cells for treatment of rat spinal cord injury. Cell Transplantation. PMID 27938489 DOI: 10.3727/096368916X693671 |
0.363 |
|
2016 |
Jeevan DS, Cooper JB, Braun A, Murali R, Jhanwar-Uniyal M. Molecular Pathways Mediating Metastases to the Brain via Epithelial-to-Mesenchymal Transition: Genes, Proteins, and Functional Analysis. Anticancer Research. 36: 523-32. PMID 26851006 |
0.351 |
|
2016 |
Machova Urdzikova L, Karova K, Ruzicka J, Kloudova A, Shannon C, Dubisova J, Murali R, Kubinova S, Sykova E, Jhanwar-Uniyal M, Jendelova P. The Anti-Inflammatory Compound Curcumin Enhances Locomotor and Sensory Recovery after Spinal Cord Injury in Rats by Immunomodulation. International Journal of Molecular Sciences. 17. PMID 26729105 DOI: 10.3390/Ijms17010049 |
0.302 |
|
2016 |
Ronecker JS, Lee P, Sridhara S, LaBagnara M, Murali R, Jhanwar-Uniyal M. Abstract 1280: The intersection of the PI3K/mTOR and HIPPO pathways: a potential therapeutic target for medulloblastoma Cancer Research. 76: 1280-1280. DOI: 10.1158/1538-7445.Am2016-1280 |
0.544 |
|
2015 |
Neil J, Shannon C, Mohan A, Laurent D, Murali R, Jhanwar-Uniyal M. ATP-site binding inhibitor effectively targets mTORC1 and mTORC2 complexes in glioblastoma. International Journal of Oncology. PMID 26719046 DOI: 10.3892/Ijo.2015.3311 |
0.516 |
|
2015 |
Amemori T, Ruzicka J, Romanyuk N, Jhanwar-Uniyal M, Sykova E, Jendelova P. Comparison of intraspinal and intrathecal implantation of induced pluripotent stem cell-derived neural precursors for the treatment of spinal cord injury in rats. Stem Cell Research & Therapy. 6: 257. PMID 26696415 DOI: 10.1186/S13287-015-0255-2 |
0.394 |
|
2015 |
Jhanwar-Uniyal M, Labagnara M, Friedman M, Kwasnicki A, Murali R. Glioblastoma: molecular pathways, stem cells and therapeutic targets. Cancers. 7: 538-55. PMID 25815458 DOI: 10.3390/Cancers7020538 |
0.509 |
|
2015 |
Kwasnicki A, Jeevan D, Braun A, Murali R, Jhanwar-Uniyal M. Involvement of mTOR signaling pathways in regulating growth and dissemination of metastatic brain tumors via EMT. Anticancer Research. 35: 689-96. PMID 25667447 |
0.359 |
|
2015 |
Jhanwar-Uniyal M, Gillick JL, Neil J, Tobias M, Thwing ZE, Murali R. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes. Advances in Biological Regulation. 57: 64-74. PMID 25442674 DOI: 10.1016/J.Jbior.2014.09.004 |
0.527 |
|
2015 |
Gillick JL, Thwing ZE, Sridhara S, Murali R, Jhanwar-Uniyal M. Abstract 686: Targeting glioblastoma and its stem cells using novel small molecule inhibitors of the mTOR pathway Cancer Research. 75: 686-686. DOI: 10.1158/1538-7445.Am2015-686 |
0.604 |
|
2014 |
Urdzíková LM, Růžička J, LaBagnara M, Kárová K, Kubinová Š, Jiráková K, Murali R, Syková E, Jhanwar-Uniyal M, Jendelová P. Human mesenchymal stem cells modulate inflammatory cytokines after spinal cord injury in rat. International Journal of Molecular Sciences. 15: 11275-93. PMID 24968269 DOI: 10.3390/Ijms150711275 |
0.344 |
|
2014 |
Ormond DR, Shannon C, Oppenheim J, Zeman R, Das K, Murali R, Jhanwar-Uniyal M. Stem cell therapy and curcumin synergistically enhance recovery from spinal cord injury. Plos One. 9: e88916. PMID 24558450 DOI: 10.1371/Journal.Pone.0088916 |
0.412 |
|
2014 |
Karsy M, Albert L, Murali R, Jhanwar-Uniyal M. The impact of arsenic trioxide and all-trans retinoic acid on p53 R273H-codon mutant glioblastoma. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 35: 4567-80. PMID 24399651 DOI: 10.1007/S13277-013-1601-6 |
0.588 |
|
2014 |
LaBagnara M, Lambert K, Sridhara S, Tobias M, Murali R, Jhanwar-Uniyal M. Abstract 1927: Tumor suppressor PTEN regulates cancer stem cells of glioblastoma multiforme: identification of signaling pathways as targets of therapy Cancer Research. 74: 1927-1927. DOI: 10.1158/1538-7445.Am2014-1927 |
0.591 |
|
2013 |
Friedman MD, Jeevan DS, Tobias M, Murali R, Jhanwar-Uniyal M. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid. Oncology Reports. 30: 1645-50. PMID 23877261 DOI: 10.3892/Or.2013.2625 |
0.569 |
|
2013 |
Jhanwar-Uniyal M, Jeevan D, Neil J, Shannon C, Albert L, Murali R. Deconstructing mTOR complexes in regulation of Glioblastoma Multiforme and its stem cells. Advances in Biological Regulation. 53: 202-10. PMID 23231881 DOI: 10.1016/J.Jbior.2012.10.001 |
0.534 |
|
2013 |
Kwasnicki A, Jeevan D, Goyal A, Braun A, Murali R, Jhanwar-Uniyal M. Abstract 4358: Involvement of mTOR pathway in metastatic brain tumors. Cancer Research. 73: 4358-4358. DOI: 10.1158/1538-7445.Am2013-4358 |
0.509 |
|
2013 |
Jeevan DS, Sridhara S, Braun A, Murali R, Jhanwar-Uniyal M. Abstract 273: Molecular markers promoting metastases to the brain via EMT: Genes, proteins, and functional analysis. Cancer Research. 73: 273-273. DOI: 10.1158/1538-7445.Am2013-273 |
0.477 |
|
2012 |
Mohan AL, Friedman MD, Ormond DR, Tobias M, Murali R, Jhanwar-Uniyal M. PI3K/mTOR signaling pathways in medulloblastoma. Anticancer Research. 32: 3141-6. PMID 22843885 |
0.48 |
|
2012 |
Ormond DR, Peng H, Zeman R, Das K, Murali R, Jhanwar-Uniyal M. Recovery from spinal cord injury using naturally occurring antiinflammatory compound curcumin: laboratory investigation. Journal of Neurosurgery. Spine. 16: 497-503. PMID 22324804 DOI: 10.3171/2012.1.Spine11769 |
0.3 |
|
2012 |
Neil J, Shannon C, Tobias M, Braun A, Murali R, Jhanwar-Uniyal M. Abstract 902: Effective and selective targeting of glioblastoma multiforme using an active-site inhibitor of mTORC1/mTORC2 kinase Cancer Research. 72: 902-902. DOI: 10.1158/1538-7445.Am2012-902 |
0.53 |
|
2011 |
Sica G, Lama G, Anile C, Geloso MC, La Torre G, De Bonis P, Maira G, Lauriola L, Jhanwar-Uniyal M, Mangiola A. Assessment of angiogenesis by CD105 and nestin expression in peritumor tissue of glioblastoma. International Journal of Oncology. 38: 41-9. PMID 21109924 DOI: 10.3892/Ijo_00000822 |
0.32 |
|
2011 |
Jhanwar-Uniyal M, Albert L, McKenna E, Karsy M, Rajdev P, Braun A, Murali R. Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: role of Akt/mTOR and MAPK pathways. Advances in Enzyme Regulation. 51: 164-70. PMID 21035497 DOI: 10.1016/J.Advenzreg.2010.09.017 |
0.643 |
|
2011 |
Friedman MD, Shannon CM, Tobias M, Braun A, Murali R, Jhanwar-Uniyal M. Abstract 3392: Regulation and maintenance of cancer stem cells of glioblastoma multiforme: The role of mTOR/MAPK signaling pathways Cancer Research. 71: 3392-3392. DOI: 10.1158/1538-7445.Am2011-3392 |
0.574 |
|
2011 |
Shannon CM, Mohan A, Braun A, Murali R, Jhanwar-Uniyal M. Abstract 1670: Targeting PI3K/mTOR/MAPK pathway in inhibition of cell growth and dissemination of glioblastoma multiforme Cancer Research. 71: 1670-1670. DOI: 10.1158/1538-7445.Am2011-1670 |
0.54 |
|
2010 |
Karsy M, Albert L, Tobias ME, Murali R, Jhanwar-Uniyal M. All-trans retinoic acid modulates cancer stem cells of glioblastoma multiforme in an MAPK-dependent manner. Anticancer Research. 30: 4915-20. PMID 21187470 |
0.626 |
|
2010 |
Karsy M, Ormond DR, Braun A, Murali R, Jhanwar-Uniyal M. Abstract 5153: Cancer stem cells of glioblastoma multiforme: regulation by the mTOR pathway Cancer Research. 70: 5153-5153. DOI: 10.1158/1538-7445.Am10-5153 |
0.694 |
|
2010 |
Sica G, Lama G, Proietti G, Mangiola A, Maira G, Anile C, Lauriola L, Torre GL, Jhanwar-Uniyal M. Abstract 4676: Understanding progenitor cells in the peritumor region of glioblastoma: GD3 ganglioside and NG2 proteoglycan expression Cancer Research. 70: 4676-4676. DOI: 10.1158/1538-7445.Am10-4676 |
0.438 |
|
2010 |
Ormond DR, McKenna E, Karsy M, Braun A, Murali R, Jhanwar-Uniyal M. Abstract 3399: STAT3 promotes metastasis to the brain: Demonstrated by protein, gene, and functional analysis Cancer Research. 70: 3399-3399. DOI: 10.1158/1538-7445.Am10-3399 |
0.62 |
|
2009 |
Albert L, Karsy M, Murali R, Jhanwar-Uniyal M. Inhibition of mTOR Activates the MAPK Pathway in Glioblastoma Multiforme. Cancer Genomics & Proteomics. 6: 255-61. PMID 19996130 |
0.607 |
|
2009 |
Gulati N, Karsy M, Albert L, Murali R, Jhanwar-Uniyal M. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility. International Journal of Oncology. 35: 731-40. PMID 19724909 DOI: 10.3892/Ijo_00000386 |
0.641 |
|
2009 |
Zohrabian VM, Forzani B, Chau Z, Murali R, Jhanwar-Uniyal M. Rho/ROCK and MAPK signaling pathways are involved in glioblastoma cell migration and proliferation. Anticancer Research. 29: 119-23. PMID 19331140 |
0.409 |
|
2007 |
Mangiola A, Lama G, Giannitelli C, De Bonis P, Anile C, Lauriola L, La Torre G, Sabatino G, Maira G, Jhanwar-Uniyal M, Sica G. Stem cell marker nestin and c-Jun NH2-terminal kinases in tumor and peritumor areas of glioblastoma multiforme: possible prognostic implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6970-7. PMID 18056172 DOI: 10.1158/1078-0432.Ccr-07-1229 |
0.453 |
|
2007 |
Dai BN, Yang Y, Chau Z, Jhanwar-Uniyal M. Polo-like kinase 1 regulates RhoA during cytokinesis exit in human cells. Cell Proliferation. 40: 550-7. PMID 17635521 DOI: 10.1111/J.1365-2184.2007.00447.X |
0.394 |
|
2007 |
Zohrabian VM, Nandu H, Gulati N, Khitrov G, Zhao C, Mohan A, Demattia J, Braun A, Das K, Murali R, Jhanwar-Uniyal M. Gene expression profiling of metastatic brain cancer. Oncology Reports. 18: 321-8. PMID 17611651 DOI: 10.3892/Or.18.2.321 |
0.41 |
|
2007 |
Lama G, Mangiola A, Anile C, Sabatino G, De Bonis P, Lauriola L, Giannitelli C, La Torre G, Jhanwar-Uniyal M, Sica G, Maira G. Activated ERK1/2 expression in glioblastoma multiforme and in peritumor tissue. International Journal of Oncology. 30: 1333-42. PMID 17487353 DOI: 10.3892/Ijo.30.6.1333 |
0.472 |
|
2006 |
Gulati N, Laudet B, Zohrabian VM, Murali R, Jhanwar-Uniyal M. The antiproliferative effect of Quercetin in cancer cells is mediated via inhibition of the PI3K-Akt/PKB pathway. Anticancer Research. 26: 1177-81. PMID 16619521 |
0.394 |
|
2006 |
Gulati AP, Yang YM, Harter D, Mukhopadhyay A, Aggarwal BB, Aggarwal BA, Benzil DL, Whysner J, Albino AP, Murali R, Jhanwar-Uniyal M. Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1. Molecular Carcinogenesis. 45: 26-37. PMID 16267831 DOI: 10.1002/Mc.20149 |
0.446 |
|
2006 |
Gulati AP, Yang YM, Harter D, Mukhopadhyay A, Aggarwal BB, Benzil DL, Whysner J, Albino AP, Murali R, Jhanwar-Uniyal M. Erratum: Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-κB, but not c-Jun N-terminal kinase and activated protein-1 (Molecular Carcinogenesis (2005) 45 (26-37)) Molecular Carcinogenesis. 45. DOI: 10.1002/Mc.20251 |
0.376 |
|
2004 |
Xie S, Wang Q, Ruan Q, Liu T, Jhanwar-Uniyal M, Guan K, Dai W. MEK1-induced Golgi dynamics during cell cycle progression is partly mediated by Polo-like kinase-3. Oncogene. 23: 3822-9. PMID 15021912 DOI: 10.1038/Sj.Onc.1207479 |
0.402 |
|
2004 |
Ruan Q, Wang Q, Xie S, Fang Y, Darzynkiewicz Z, Guan K, Jhanwar-Uniyal M, Dai W. Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle. Experimental Cell Research. 294: 51-9. PMID 14980500 DOI: 10.1016/J.Yexcr.2003.10.022 |
0.326 |
|
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