Lena Al-Harthi - Publications

Affiliations: 
Rush University, Chicago, IL, United States 
Area:
Virology Biology, Immunology, Neuroscience Biology

100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Albalawi YA, Shull T, Virdi A, Subra C, Mitchell J, Slike BM, Jian N, Krebs SJ, Sacdalan C, Ratnaratorn N, Hsu DC, Phanuphak N, Spudich S, Trautmann L, Al-Harthi L. CD4dimCD8bright T cells are inversely associated with neuro-inflammatory markers among people living with HIV. Aids (London, England). PMID 37792358 DOI: 10.1097/QAD.0000000000003743  0.54
2023 Virdi AK, Ho S, Seaton MS, Olali AZ, Narasipura SD, Barbian HJ, Olivares LJ, Gonzalez H, Winchester LC, Podany AT, Ross RD, Al-Harthi L, Wallace J. An Efficient Humanized Mouse Model for Oral Anti-Retroviral Administration. Cells. 12. PMID 37048107 DOI: 10.3390/cells12071034  0.501
2023 Wahl A, Al-Harthi L. HIV infection of non-classical cells in the brain. Retrovirology. 20: 1. PMID 36639783 DOI: 10.1186/s12977-023-00616-9  0.529
2022 Khodr CE, Chen L, Al-Harthi L, Hu XT. HIV-Induced Hyperactivity of Striatal Neurons Is Associated with Dysfunction of Voltage-Gated Calcium and Potassium Channels at Middle Age. Membranes. 12. PMID 36005652 DOI: 10.3390/membranes12080737  0.35
2022 Albalawi YA, Narasipura SD, Al-Harthi L. Wnt/β-Catenin Protects Lymphocytes from HIV-Mediated Apoptosis via Induction of Bcl-xL. Viruses. 14. PMID 35891449 DOI: 10.3390/v14071469  0.488
2022 Albalawi YA, Narasipura SD, Olivares LJ, Al-Harthi L. CD4 CD8 T Cells Home to the Brain and Mediate HIV Neuroinvasion. Journal of Virology. e0080422. PMID 35852355 DOI: 10.1128/jvi.00804-22  0.476
2022 Wallace J, Gonzalez H, Rajan R, Narasipura SD, Virdi AK, Olali AZ, Naqib A, Arbieva Z, Maienschein-Cline M, Al-Harthi L. Anti-HIV Drugs Cause Mitochondrial Dysfunction in Monocyte-Derived Macrophages. Antimicrobial Agents and Chemotherapy. e0194121. PMID 35293780 DOI: 10.1128/aac.01941-21  0.453
2022 Barbian HJ, Seaton MS, Narasipura SD, Wallace J, Rajan R, Sha BE, Al-Harthi L. β-catenin regulates HIV latency and modulates HIV reactivation. Plos Pathogens. 18: e1010354. PMID 35255110 DOI: 10.1371/journal.ppat.1010354  0.533
2021 Ash MK, Al-Harthi L, Schneider JR. HIV in the Brain: Identifying Viral Reservoirs and Addressing the Challenges of an HIV Cure. Vaccines. 9. PMID 34451992 DOI: 10.3390/vaccines9080867  0.529
2020 Chen L, Al-Harthi L, Hu XT. Triumeq Increases Excitability of Pyramidal Neurons in the Medial Prefrontal Cortex by Facilitating Voltage-Gated Ca Channel Function. Frontiers in Pharmacology. 11: 617149. PMID 33584297 DOI: 10.3389/fphar.2020.617149  0.303
2020 Olali AZ, Sharma A, Shi Q, Hoover DR, Weber KM, French AL, McKay HS, Tien PC, Al-Harthi L, Yin MT, Ross RD. Change in circulating undercarboxylated osteocalcin (ucOCN) is associated with fat accumulation in HIV-seropositive women. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 33399313 DOI: 10.1097/QAI.0000000000002617  0.386
2020 Virdi AK, Wallace J, Barbian H, Richards MH, Ritz EM, Sha B, Al-Harthi L. CD32 is enriched on CD4dimCD8bright T cells. Plos One. 15: e0239157. PMID 32960910 DOI: 10.1371/journal.pone.0239157  0.56
2020 Wallace J, Narasipura SD, Sha BE, French AL, Al-Harthi L. Canonical Wnts Mediate CD8 T Cell Noncytolytic Anti-HIV-1 Activity and Correlate with HIV-1 Clinical Status. Journal of Immunology (Baltimore, Md. : 1950). PMID 32887752 DOI: 10.4049/Jimmunol.1801379  0.672
2020 Robinson KF, Narasipura SD, Wallace J, Ritz EM, Al-Harthi L. Negative regulation of IL-8 in human astrocytes depends on β-catenin while positive regulation is mediated by TCFs/LEF/ATF2 interaction. Cytokine. 136: 155252. PMID 32818703 DOI: 10.1016/J.Cyto.2020.155252  0.314
2020 Al-Harthi L, Campbell EM, Schneider JA, Bennett DA. What HIV in the brain can teach us about SARS-CoV-2 neurologic complications? Aids Research and Human Retroviruses. PMID 32683890 DOI: 10.1089/Aid.2020.0161  0.425
2020 Robinson KF, Narasipura SD, Wallace J, Ritz EM, Al-Harthi L. β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes. Cell Communication and Signaling : Ccs. 18: 93. PMID 32546183 DOI: 10.1186/S12964-020-00565-2  0.317
2020 Lutgen V, Narasipura SD, Barbian HJ, Richards M, Wallace J, Razmpour R, Buzhdygan T, Ramirez SH, Prevedel L, Eugenin EA, Al-Harthi L. HIV infects astrocytes in vivo and egresses from the brain to the periphery. Plos Pathogens. 16: e1008381. PMID 32525948 DOI: 10.1371/Journal.Ppat.1008381  0.572
2020 Ross RD, Sharma A, Shi Q, Hoover DR, Weber KM, Tien PC, French AL, Al-Harthi L, Yin MT. Circulating sclerostin is associated with bone mineral density independent of HIV-serostatus. Bone Reports. 12: 100279. PMID 32455152 DOI: 10.1016/J.Bonr.2020.100279  0.408
2020 Borenstein R, Hanson BA, Markosyan RM, Gallo ES, Narasipura SD, Bhutta M, Shechter O, Lurain NS, Cohen FS, Al-Harthi L, Nicholson DA. Ginkgolic acid inhibits fusion of enveloped viruses. Scientific Reports. 10: 4746. PMID 32179788 DOI: 10.1038/S41598-020-61700-0  0.316
2020 Gonzalez H, Podany A, Al-Harthi L, Wallace J. The far-reaching HAND of cART: cART effects on astrocytes. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 32147775 DOI: 10.1007/S11481-020-09907-W  0.533
2019 Chen L, Khodr CE, Al-Harthi L, Hu XT. Aging and HIV-1 alter the function of specific K channels in prefrontal cortex pyramidal neurons. Neuroscience Letters. 134341. PMID 31255727 DOI: 10.1016/J.Neulet.2019.134341  0.39
2019 Al-Harthi L, Joseph J, Nath A. Correction to: Astrocytes as an HIV CNS reservoir: highlights and reflections of an NIMH-sponsored symposium. Journal of Neurovirology. PMID 31041681 DOI: 10.1007/S13365-019-00726-1  0.467
2017 Khodr CE, Chen L, Al-Harthi L, Hu XT. Aging alters voltage-gated calcium channels in prefrontal cortex pyramidal neurons in the HIV brain. Journal of Neurovirology. PMID 29090376 DOI: 10.1007/S13365-017-0588-Y  0.317
2017 Wallace J, Lutgen V, Avasarala S, St Croix B, Winn RA, Al-Harthi L. Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro-and anti-inflammatory cytokines. Immunology. PMID 28872671 DOI: 10.1111/Imm.12830  0.367
2017 Yu C, Narasipura SD, Richards MH, Hu XT, Yamamoto B, Al-Harthi L. HIV and drug abuse mediate astrocyte senescence in a β-catenin-dependent manner leading to neuronal toxicity. Aging Cell. PMID 28612507 DOI: 10.1111/Acel.12593  0.579
2017 Yu C, Seaton M, Letendre S, Heaton R, Al-Harthi L. Plasma Dickkopf-related Protein 1, an antagonist of the Wnt pathway, is associated with HIV-associated neurocognitive impairment. Aids (London, England). PMID 28358733 DOI: 10.1097/Qad.0000000000001481  0.449
2016 Khodr CE, Chen L, Dave S, Al-Harthi L, Hu XT. Combined chronic blockade of hyper-active L-type calcium channels and NMDA receptors ameliorates HIV-1 associated hyper-excitability of mPFC pyramidal neurons. Neurobiology of Disease. PMID 27326669 DOI: 10.1016/J.Nbd.2016.06.008  0.446
2016 Kerzerho J, McIlvaine EJ, Anthony P, Mack WJ, Wang CH, Frederick T, Operskalski E, Chen Z, Al-Harthi L, Landay A, Young MA, Tien PC, Augenbraun M, Strickler HD, Akbari O, et al. Impact of Hepatitis C Virus on the Circulating Levels of IL-7 in HIV-1 Coinfected Women. Journal of Acquired Immune Deficiency Syndromes (1999). 71: 172-180. PMID 26761519 DOI: 10.1097/Qai.0000000000000832  0.536
2015 Richards MH, Narasipura SD, Seaton MS, Lutgen V, Al-Harthi L. Migration of CD8+ T Cells into the Central Nervous System Gives Rise to Highly Potent Anti-HIV CD4dimCD8bright T Cells in a Wnt Signaling-Dependent Manner. Journal of Immunology (Baltimore, Md. : 1950). PMID 26582945 DOI: 10.4049/Jimmunol.1501394  0.585
2015 Zhang YG, Wu S, Lu R, Richards MH, Huelsmann EJ, Lacek AT, Nabatiyan A, Chen D, Al-Harthi L, Zloza A, Sun J. HIV Infection Leads to Redistribution of Leaky Claudin-2 in the Intestine of Humanized SCID IL-2R(-/-) Hu-PBMC Mice. Aids Research and Human Retroviruses. PMID 25853489 DOI: 10.1089/Aid.2014.0341  0.706
2015 Richards MH, Narasipura SD, Kim S, Seaton MS, Lutgen V, Al-Harthi L. Dynamic interaction between astrocytes and infiltrating PBMCs in context of neuroAIDS. Glia. 63: 441-51. PMID 25331637 DOI: 10.1002/Glia.22763  0.593
2014 Aljawai Y, Richards MH, Seaton MS, Narasipura SD, Al-Harthi L. β-Catenin/TCF-4 signaling regulates susceptibility of macrophages and resistance of monocytes to HIV-1 productive infection. Current Hiv Research. 12: 164-73. PMID 24862328 DOI: 10.2174/1570162X12666140526122249  0.58
2014 Richards MH, Seaton MS, Wallace J, Al-Harthi L. Porcupine is not required for the production of the majority of Wnts from primary human astrocytes and CD8+ T cells. Plos One. 9: e92159. PMID 24647048 DOI: 10.1371/Journal.Pone.0092159  0.351
2014 Lu R, Wu S, Zhang Y, Xia Y, Huelsmann EJ, Lacek AT, Nabatiyan A, Richards MH, Narasipura SD, Lutgen V, Chen H, Kaufman HL, Chen D, Al-Harthi L, Zloza A, et al. HIV infection accelerates gastrointestinal tumor outgrowth in NSG-HuPBL mice. Aids Research and Human Retroviruses. 30: 677-84. PMID 24593860 DOI: 10.1089/Aid.2013.0289  0.753
2014 Narasipura SD, Kim S, Al-Harthi L. Epigenetic regulation of HIV-1 latency in astrocytes. Journal of Virology. 88: 3031-8. PMID 24352441 DOI: 10.1128/Jvi.03333-13  0.553
2014 Lu R, Wu S, Zhang Y, Xia Y, Huelsmann EJ, Lacek AT, Nabatiyan AS, Richards MH, Narasipura S, Lutgen V, Chen H, Kaufman HL, Chen D, Al-Harthi L, Zloza A, et al. Tu1692 HIV Infection Accelerates Gastrointestinal Tumor Outgrowth in Humanized NSG-HuPBL Mice Gastroenterology. 146: S-820. DOI: 10.1016/S0016-5085(14)62969-3  0.753
2013 Szotek EL, Narasipura SD, Al-Harthi L. 17β-Estradiol inhibits HIV-1 by inducing a complex formation between β-catenin and estrogen receptor α on the HIV promoter to suppress HIV transcription. Virology. 443: 375-83. PMID 23769242 DOI: 10.1016/J.Virol.2013.05.027  0.56
2012 Henderson LJ, Sharma A, Monaco MC, Major EO, Al-Harthi L. Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription through its intact core and cysteine-rich domains inhibits Wnt/β-catenin signaling in astrocytes: relevance to HIV neuropathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16306-13. PMID 23152614 DOI: 10.1523/Jneurosci.3145-12.2012  0.562
2012 Al-Harthi L. Interplay between Wnt/β-catenin signaling and HIV: virologic and biologic consequences in the CNS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 731-9. PMID 23065461 DOI: 10.1007/S11481-012-9411-Y  0.508
2012 Al-Harthi L. Comment on "CD4+ CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection". Journal of Immunology (Baltimore, Md. : 1950). 188: 5809; author reply 5. PMID 22675214 DOI: 10.4049/Jimmunol.1290028  0.631
2012 Henderson LJ, Narasipura SD, Adarichev V, Kashanchi F, Al-Harthi L. Identification of novel T cell factor 4 (TCF-4) binding sites on the HIV long terminal repeat which associate with TCF-4, β-catenin, and SMAR1 to repress HIV transcription. Journal of Virology. 86: 9495-503. PMID 22674979 DOI: 10.1128/Jvi.00486-12  0.574
2012 Zloza A, Kohlhapp FJ, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O'Sullivan JA, Varanasi V, Williams JW, Jagoda MC, Bellavance EC, Marzo AL, Thomas PG, Zafirova B, Poli? B, ... Al-Harthi L, et al. NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses. Nature Medicine. 18: 422-8. PMID 22366950 DOI: 10.1038/Nm.2683  0.706
2012 Narasipura SD, Henderson LJ, Fu SW, Chen L, Kashanchi F, Al-Harthi L. Role of β-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes. Journal of Virology. 86: 1911-21. PMID 22156527 DOI: 10.1128/Jvi.06266-11  0.567
2012 Al-Harthi L. Unconventional CD8+ T cells (CD4dimCD8bright cells) in anti-HIV immunity and neuropathogenesis Journal of Antivirals & Antiretrovirals. 1. DOI: 10.4172/1948-5964.S1.007  0.538
2011 Al-Harthi L, Kashanchi F. Mechanisms of HIV-1 latency post HAART treatment area. Current Hiv Research. 9: 552-3. PMID 22409272 DOI: 10.2174/157016211798998763  0.529
2011 Wu J, Richards MH, Huang J, Al-Harthi L, Xu X, Lin R, Xie F, Gibson AW, Edberg JC, Kimberly RP. Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions. Plos One. 6: e26143. PMID 22022540 DOI: 10.1371/Journal.Pone.0026143  0.3
2011 Sharma A, Hu XT, Napier TC, Al-Harthi L. Methamphetamine and HIV-1 Tat down regulate β-catenin signaling: implications for methampetamine abuse and HIV-1 co-morbidity. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 6: 597-607. PMID 21744004 DOI: 10.1007/S11481-011-9295-2  0.547
2011 Li W, Henderson LJ, Major EO, Al-Harthi L. IFN-gamma mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the beta-catenin pathway (DKK1) in a STAT 3-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 186: 6771-8. PMID 21562161 DOI: 10.4049/Jimmunol.1100099  0.62
2011 Kehn-Hall K, Guendel I, Carpio L, Skaltsounis L, Meijer L, Al-Harthi L, Steiner JP, Nath A, Kutsch O, Kashanchi F. Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors. Virology. 415: 56-68. PMID 21514616 DOI: 10.1016/J.Virol.2011.03.025  0.55
2011 Henderson LJ, Al-Harthi L. Role of β-catenin/TCF-4 signaling in HIV replication and pathogenesis: insights to informing novel anti-HIV molecular therapeutics. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 6: 247-59. PMID 21384147 DOI: 10.1007/S11481-011-9266-7  0.592
2011 Li W, Wu H, Henderson L, Al-Harthi L. OL-069 Interaction between β-catenin and IFN γ signaling to regulate HIV replication in brain astrocytes International Journal of Infectious Diseases. 15: S38. DOI: 10.1016/S1201-9712(11)60133-1  0.385
2010 Schenkel JM, Zloza A, Li W, Narasipura SD, Al-Harthi L. Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 2013-9. PMID 20631314 DOI: 10.4049/Jimmunol.0902572  0.67
2010 Kovacs A, Karim R, Mack WJ, Xu J, Chen Z, Operskalski E, Frederick T, Landay A, Voris J, Spencer LS, Young MA, Tien PC, Augenbraun M, Strickler HD, Al-Harthi L. Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus. The Journal of Infectious Diseases. 201: 823-34. PMID 20151840 DOI: 10.1086/650997  0.598
2009 Zloza A, Schenkel JM, Tenorio AR, Martinson JA, Jeziorczak PM, Al-Harthi L. Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface. Blood. 114: 3841-53. PMID 19700667 DOI: 10.1182/Blood-2009-02-202481  0.728
2008 Kovacs A, Al-Harthi L, Christensen S, Mack W, Cohen M, Landay A. CD8(+) T cell activation in women coinfected with human immunodeficiency virus type 1 and hepatitis C virus. The Journal of Infectious Diseases. 197: 1402-7. PMID 18444798 DOI: 10.1086/587696  0.556
2008 Kumar A, Zloza A, Moon RT, Watts J, Tenorio AR, Al-Harthi L. Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. Journal of Virology. 82: 2813-20. PMID 18199649 DOI: 10.1128/Jvi.02498-07  0.719
2007 Al-Harthi L, MaWhinney S, Connick E, Schooley RT, Forster JE, Benson C, Thompson M, Judson F, Palella F, Landay A. Immunophenotypic alterations in acute and early HIV infection. Clinical Immunology (Orlando, Fla.). 125: 299-308. PMID 17916441 DOI: 10.1016/J.Clim.2007.08.011  0.54
2007 Carroll-Anzinger D, Kumar A, Adarichev V, Kashanchi F, Al-Harthi L. Human immunodeficiency virus-restricted replication in astrocytes and the ability of gamma interferon to modulate this restriction are regulated by a downstream effector of the Wnt signaling pathway. Journal of Virology. 81: 5864-71. PMID 17392368 DOI: 10.1128/Jvi.02234-06  0.762
2007 Martinson JA, Tenorio AR, Montoya CJ, Al-Harthi L, Gichinga CN, Krieg AM, Baum LL, Landay AL. Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals. Immunology. 120: 526-35. PMID 17343615 DOI: 10.1111/J.1365-2567.2007.02530.X  0.634
2007 Bahbouhi B, Landay A, Tenorio A, Al-Harthi L. HIV infection of primary CD4+ Th2 cells, defined by expression of the chemoattractant receptor-homologous (CRTH2), induces a Th0 phenotype. Aids Research and Human Retroviruses. 23: 269-77. PMID 17331033 DOI: 10.1089/Aid.2006.0151  0.61
2007 Sailer CA, Pott GB, Dinarello CA, Whinney SM, Forster JE, Larson-Duran JK, Landay A, Al-Harthi L, Schooley RT, Benson CA, Judson FN, Thompson M, Palella FJ, Shapiro L. Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon- gamma levels. The Journal of Infectious Diseases. 195: 734-8. PMID 17262717 DOI: 10.1086/511435  0.586
2007 Laskus T, Operskalski EA, Radkowski M, Wilkinson J, Mack WJ, deGiacomo M, Al-Harthi L, Chen Z, Xu J, Kovacs A. Negative-strand hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells from anti-HCV-positive/HIV-infected women. The Journal of Infectious Diseases. 195: 124-33. PMID 17152016 DOI: 10.1086/509897  0.389
2006 Montoya CJ, Jie HB, Al-Harthi L, Mulder C, Patiño PJ, Rugeles MT, Krieg AM, Landay AL, Wilson SB. Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 1028-39. PMID 16818759 DOI: 10.4049/Jimmunol.177.2.1028  0.36
2006 Al-Harthi L, Voris J, Du W, Wright D, Nowicki M, Frederick T, Landay A, Kovacs A. Evaluating the impact of hepatitis C virus (HCV) on highly active antiretroviral therapy-mediated immune responses in HCV/HIV-coinfected women: role of HCV on expression of primed/memory T cells. The Journal of Infectious Diseases. 193: 1202-10. PMID 16586355 DOI: 10.1086/500843  0.421
2006 Managlia EZ, Landay A, Al-Harthi L. Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway. Virology. 350: 443-52. PMID 16542695 DOI: 10.1016/J.Virol.2006.02.019  0.789
2006 Zloza A, Al-Harthi L. Multiple populations of T lymphocytes are distinguished by the level of CD4 and CD8 coexpression and require individual consideration. Journal of Leukocyte Biology. 79: 4-6. PMID 16380600 DOI: 10.1189/Jlb.0805455  0.667
2006 Carroll-Anzinger D, Al-Harthi L. Gamma interferon primes productive human immunodeficiency virus infection in astrocytes. Journal of Virology. 80: 541-4. PMID 16352578 DOI: 10.1128/Jvi.80.1.541-544.2006  0.762
2005 Managlia EZ, Landay A, Al-Harthi L. Interleukin-7 signalling is sufficient to phenotypically and functionally prime human CD4 naive T cells. Immunology. 114: 322-35. PMID 15720434 DOI: 10.1111/J.1365-2567.2004.02089.X  0.736
2004 De Vera MJ, Al-Harthi L, Gewurz AT. Assessing thymopoiesis in patients with common variable immunodeficiency as measured by T-cell receptor excision circles. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 93: 478-84. PMID 15562888 DOI: 10.1016/S1081-1206(10)61416-0  0.387
2004 Managlia EZ, Carroll D, Zloza A, Al-Harthi L. Immune modulation of HIV replication: relevance to HIV immuno- and neuro-pathogenesis. Current Hiv Research. 2: 395-401. PMID 15544459 DOI: 10.2174/1570162043351020  0.835
2004 Bahbouhi B, Landay A, Al-Harthi L. Dynamics of cytokine expression in HIV productively infected primary CD4+ T cells. Blood. 103: 4581-7. PMID 14764521 DOI: 10.1182/Blood-2003-12-4172  0.598
2004 Bahbouhi B, al-Harthi L. Enriching for HIV-infected cells using anti-gp41 antibodies indirectly conjugated to magnetic microbeads. Biotechniques. 36: 139-47. PMID 14740496 DOI: 10.2144/04361Rr05  0.598
2004 Al-Harthi L, Voris J, Patterson BK, Becker S, Eron J, Smith KY, D'Amico R, Mildvan D, Snidow J, Pobiner B, Yau L, Landay A. Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients Hiv Medicine. 5: 55-65. PMID 14731171 DOI: 10.1111/J.1468-1293.2004.00186.X  0.527
2003 Jacobson JM, Lederman MM, Spritzler J, Valdez H, Tebas P, Skowron G, Wang R, Jackson JB, Fox L, Landay A, Gilbert MJ, O'Neil D, Bancroft L, Al-Harthi L, Jacobson MA, et al. Granulocyte-macrophage colony-stimulating factor induces modest increases in plasma human immunodeficiency virus (HIV) type 1 RNA levels and CD4+ lymphocyte counts in patients with uncontrolled HIV infection. The Journal of Infectious Diseases. 188: 1804-14. PMID 14673758 DOI: 10.1086/379899  0.594
2003 Poirier MC, Divi RL, Al-Harthi L, Olivero OA, Nguyen V, Walker B, Landay AL, Walker VE, Charurat M, Blattner WA. Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers. Journal of Acquired Immune Deficiency Syndromes (1999). 33: 175-83. PMID 12794551 DOI: 10.1097/00126334-200306010-00010  0.518
2003 Zloza A, Sullivan YB, Connick E, Landay AL, Al-Harthi L. CD8+ T cells that express CD4 on their surface (CD4dimCD8bright T cells) recognize an antigen-specific target, are detected in vivo, and can be productively infected by T-tropic HIV. Blood. 102: 2156-64. PMID 12791668 DOI: 10.1182/Blood-2002-07-1972  0.801
2003 Fleuridor R, Wilson B, Hou R, Landay A, Kessler H, Al-Harthi L. CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection. Immunology. 108: 3-9. PMID 12519296 DOI: 10.1046/J.1365-2567.2003.01560.X  0.629
2002 Al-Harthi L, Landay A. Immune recovery in HIV disease: role of the thymus and T cell expansion in immune reconstitution strategies. Journal of Hematotherapy & Stem Cell Research. 11: 777-86. PMID 12427284 DOI: 10.1089/152581602760404586  0.477
2002 Nokta MA, Li XD, Al-Harthi L, Nichols J, Pou A, Asmuth D, Landay A, Pollard RB. Entrapment of recent thymic emigrants in lymphoid tissues from HIV-infected patients: association with HIV cellular viral load. Aids (London, England). 16: 2119-27. PMID 12409732 DOI: 10.1097/00002030-200211080-00003  0.625
2002 Steffens CM, Managlia EZ, Landay A, Al-Harthi L. Interleukin-7-treated naive T cells can be productively infected by T-cell-adapted and primary isolates of human immunodeficiency virus 1. Blood. 99: 3310-8. PMID 11964298 DOI: 10.1182/Blood.V99.9.3310  0.816
2002 Al-Harthi L, Guilbert LJ, Hoxie JA, Landay A. Trophoblasts are productively infected by CD4-independent isolate of HIV type 1. Aids Research and Human Retroviruses. 18: 13-7. PMID 11804552 DOI: 10.1089/088922202753394673  0.631
2001 Steffens CM, Smith KY, Landay A, Shott S, Truckenbrod A, Russert M, Al-Harthi L. T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals. Aids (London, England). 15: 1757-64. PMID 11579236 DOI: 10.1097/00002030-200109280-00003  0.6
2001 Al-Harthi L, Kovacs A, Coombs RW, Reichelderfer PS, Wright DJ, Cohen MH, Cohn J, Cu-Uvin S, Watts H, Lewis S, Beckner S, Landay A. A menstrual cycle pattern for cytokine levels exists in HIV-positive women: implication for HIV vaginal and plasma shedding. Aids (London, England). 15: 1535-43. PMID 11504986 DOI: 10.1097/00002030-200108170-00011  0.544
2001 Sullivan YB, Landay AL, Zack JA, Kitchen SG, Al-Harthi L. Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells. Immunology. 103: 270-80. PMID 11454056 DOI: 10.1046/J.1365-2567.2001.01243.X  0.775
2001 al-Harthi L, Landay A. HIV in the female genital tract: viral shedding and mucosal immunity. Clinical Obstetrics and Gynecology. 44: 144-53. PMID 11344984 DOI: 10.1097/00003081-200106000-00005  0.581
2000 Steffens CM, Al-Harthi L, Shott S, Yogev R, Landay A. Evaluation of thymopoiesis using T cell receptor excision circles (TRECs): differential correlation between adult and pediatric TRECs and naïve phenotypes. Clinical Immunology (Orlando, Fla.). 97: 95-101. PMID 11027449 DOI: 10.1006/Clim.2000.4938  0.359
2000 Al-Harthi L, Siegel J, Spritzler J, Pottage J, Agnoli M, Landay A. Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease. Aids (London, England). 14: 761-70. PMID 10839583 DOI: 10.1097/00002030-200005050-00001  0.589
2000 Al-Harthi L, Marchetti G, Steffens CM, Poulin J, Sékaly R, Landay A. Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction-enzyme linked immunosorbent assay (PCR-ELISA). Journal of Immunological Methods. 237: 187-97. PMID 10725462 DOI: 10.1016/S0022-1759(00)00136-8  0.448
1999 Al-Harthi L, Roebuck KA, Olinger GG, Landay A, Sha BE, Hashemi FB, Spear GT. Bacterial vaginosis-associated microflora isolated from the female genital tract activates HIV-1 expression. Journal of Acquired Immune Deficiency Syndromes (1999). 21: 194-202. PMID 10421242 DOI: 10.1097/00126334-199907010-00003  0.554
1999 Steffens CM, Marchetti G, Landay A, Al-Harthi L. The human thymus: A new perspective on thymic function, aging, and hiv infection Clinical Immunology Newsletter. 19: 65-79. DOI: 10.1016/S0197-1859(00)89202-X  0.501
1998 Al-Harthi L, Roebuck KA. Human immunodeficiency virus type-1 transcription: role of the 5'-untranslated leader region (review) International Journal of Molecular Medicine. 1: 875-881. PMID 9852310 DOI: 10.3892/Ijmm.1.5.875  0.385
1998 Rabbi MF, Finnegan A, Al-Harthi L, Song S, Roebuck KA. Interleukin-10 enhances tumor necrosis factor-alpha activation of HIV-1 transcription in latently infected T cells. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 19: 321-31. PMID 9833740 DOI: 10.1097/00042560-199812010-00002  0.517
1998 Al-Harthi L, Spear GT, Hashemi FB, Landay A, Sha BE, Roebuck KA. A human immunodeficiency virus (HIV)-inducing factor from the female genital tract activates HIV-1 gene expression through the κB enhancer Journal of Infectious Diseases. 178: 1343-1351. PMID 9780254 DOI: 10.1086/314444  0.599
1998 Rabbi MF, al-Harthi L, Saifuddin M, Roebuck KA. The cAMP-dependent protein kinase A and protein kinase C-beta pathways synergistically interact to activate HIV-1 transcription in latently infected cells of monocyte/macrophage lineage. Virology. 245: 257-69. PMID 9636365 DOI: 10.1006/Viro.1998.9158  0.476
1998 Al-Harthi L, Roebuck KA, Landay A. Induction of HIV-1 replication by type 1-like cytokines, interleukin (IL)-12 and IL-15: Effect on viral transcriptional activation, cellular proliferation, and endogenous cytokine production Journal of Clinical Immunology. 18: 124-131. PMID 9533656 DOI: 10.1023/A:1023246800353  0.477
1998 Valdez H, Al-Harthi L, Landay A, Lederman MM. Rationale for immune-based therapies for HIV-1 infection. The Journal of Laboratory and Clinical Medicine. 131: 197-206. PMID 9523842 DOI: 10.1016/S0022-2143(98)90090-7  0.522
1998 Al-Harthi L, Owais M, Arya SK. Molecular inhibition of HIV type 1 by HIV type 2: effectiveness in peripheral blood mononuclear cells. Aids Research and Human Retroviruses. 14: 59-64. PMID 9453252 DOI: 10.1089/aid.1998.14.59  0.535
1997 Al-Harthi L, Roebuck KA, Kessler H, Landay A. Inhibition of cytokine-driven human immunodeficiency virus type 1 replication by protease inhibitor Journal of Infectious Diseases. 176: 1175-1179. PMID 9359716 DOI: 10.1086/514110  0.574
1997 Rabbi MF, Al-Harthi L, Roebuck KA. TNFalpha cooperates with the protein kinase A pathway to synergistically increase HIV-1 LTR transcription via downstream TRE-like cAMP response elements. Virology. 237: 422-9. PMID 9356353 DOI: 10.1006/Viro.1997.8798  0.457
1997 Spear GT, Al-Harthi L, Sha B, Saarloos MN, Hayden M, Massad LS, Benson C, Roebuck KA, Glick NR, Landay A. A potent activator of HIV-1 replication is present in the genital tract of a subset of HIV-1-infected and uninfected women Aids. 11: 1319-1326. PMID 9302440 DOI: 10.1097/00002030-199711000-00005  0.615
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