| Year |
Citation |
Score |
| 2024 |
Gupta A, Thirunavukkarasu S, Rangel-Moreno J, Ahmed M, Swanson RV, Mbandi SK, Smrcka AV, Kaushal D, Scriba TJ, Khader SA. Phospholipase C epsilon-1 (PLCƐ1) mediates macrophage activation and protection against tuberculosis. Infection and Immunity. e0049523. PMID 38451080 DOI: 10.1128/iai.00495-23 |
0.474 |
|
| 2023 |
Thirunavukkarasu S, Ahmed M, Rosa BA, Boothby M, Cho SH, Rangel-Moreno J, Mbandi SK, Schreiber V, Gupta A, Zúñiga J, Mitreva M, Kaushal D, Scriba TJ, Khader SA. Poly(ADP)ribose polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production. The Journal of Clinical Investigation. PMID 37200107 DOI: 10.1172/JCI158630 |
0.395 |
|
| 2023 |
Walker EM, Merino KM, Slisarenko N, Grasperge BF, Mehra S, Roy CJ, Kaushal D, Rout N. Impact of SIV infection on mycobacterial lipid-reactive T cell responses in Bacillus Calmette-Guérin (BCG) inoculated macaques. Frontiers in Immunology. 13: 1085786. PMID 36726992 DOI: 10.3389/fimmu.2022.1085786 |
0.393 |
|
| 2023 |
Singh B, Moodley C, Singh DK, Escobedo RA, Sharan R, Arora G, Ganatra SR, Shivanna V, Gonzalez O, Hall-Ursone S, Dick EJ, Kaushal D, Alvarez X, Mehra S. Inhibition of indoleamine dioxygenase leads to better control of tuberculosis adjunctive to chemotherapy. Jci Insight. 8. PMID 36692017 DOI: 10.1172/jci.insight.163101 |
0.391 |
|
| 2022 |
Gough M, Singh DK, Singh B, Kaushal D, Mehra S. System-wide identification of myeloid markers of TB disease and HIV-induced reactivation in the macaque model of Mtb infection and Mtb/SIV co-infection. Frontiers in Immunology. 13: 777733. PMID 36275677 DOI: 10.3389/fimmu.2022.777733 |
0.398 |
|
| 2022 |
Sharan R, Ganatra SR, Singh DK, Cole J, Foreman TW, Thippeshappa R, Peloquin CA, Shivanna V, Gonzalez O, Day CL, Gandhi NR, Dick EJ, Hall-Ursone S, Mehra S, Schlesinger LS, ... ... Kaushal D, et al. Isoniazid and rifapentine treatment effectively reduces persistent M. tuberculosis infection in macaque lungs. The Journal of Clinical Investigation. PMID 35862216 DOI: 10.1172/JCI161564 |
0.329 |
|
| 2022 |
Akter S, Chauhan KS, Dunlap MD, Choreño-Parra JA, Lu L, Esaulova E, Zúñiga J, Artyomov MN, Kaushal D, Khader SA. Mycobacterium tuberculosis infection drives a type I IFN signature in lung lymphocytes. Cell Reports. 39: 110983. PMID 35732116 DOI: 10.1016/j.celrep.2022.110983 |
0.422 |
|
| 2022 |
Gough M, Singh DK, Moodley C, Niu T, Golden NA, Kaushal D, Mehra S. Peripheral Blood Markers Correlate with the Progression of Active Tuberculosis Relative to Latent Control of Infection in Macaques. Pathogens (Basel, Switzerland). 11. PMID 35631065 DOI: 10.3390/pathogens11050544 |
0.359 |
|
| 2022 |
Khan A, Zhang K, Singh VK, Mishra A, Kachroo P, Bing T, Won JH, Mani A, Papanna R, Mann LK, Ledezma-Campos E, Aguillon-Duran G, Canaday DH, David SA, Restrepo BI, ... ... Kaushal D, et al. Human M1 macrophages express unique innate immune response genes after mycobacterial infection to defend against tuberculosis. Communications Biology. 5: 480. PMID 35590096 DOI: 10.1038/s42003-022-03387-9 |
0.389 |
|
| 2022 |
Bucşan AN, Veatch A, Singh DK, Akter S, Golden NA, Kirkpatrick M, Threeton B, Moodley C, Ahmed M, Doyle LA, Russell-Lodrigue K, Norton EB, Didier PJ, Roy CJ, Abramovitch RB, ... ... Kaushal D, et al. Response to Hypoxia and the Ensuing Dysregulation of Inflammation Impacts Pathogenicity. American Journal of Respiratory and Critical Care Medicine. PMID 35412961 DOI: 10.1164/rccm.202112-2747OC |
0.315 |
|
| 2022 |
Singh DK, Aladyeva E, Das S, Singh B, Esaulova E, Swain A, Ahmed M, Cole J, Moodley C, Mehra S, Schlesinger LS, Artyomov MN, Khader SA, Kaushal D. Myeloid cell interferon responses correlate with clearance of SARS-CoV-2. Nature Communications. 13: 679. PMID 35115549 DOI: 10.1038/s41467-022-28315-7 |
0.34 |
|
| 2022 |
McCaffrey EF, Donato M, Keren L, Chen Z, Delmastro A, Fitzpatrick MB, Gupta S, Greenwald NF, Baranski A, Graf W, Kumar R, Bosse M, Fullaway CC, Ramdial PK, Forgó E, ... ... Kaushal D, et al. The immunoregulatory landscape of human tuberculosis granulomas. Nature Immunology. 23: 318-329. PMID 35058616 DOI: 10.1038/s41590-021-01121-x |
0.329 |
|
| 2021 |
Singh B, Singh DK, Ganatra SR, Escobedo RA, Khader S, Schlesinger LS, Kaushal D, Mehra S. Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction in Nonhuman Primate TB Granulomas. Mbio. e0318921. PMID 34903057 DOI: 10.1128/mbio.03189-21 |
0.392 |
|
| 2021 |
Sharan R, Ganatra SR, Bucsan AN, Cole J, Singh DK, Alvarez X, Gough M, Alvarez C, Blakley A, Ferdin J, Thippeshappa R, Singh B, Escobedo R, Shivanna V, Dick EJ, ... ... Kaushal D, et al. Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a tuberculosis/simian immunodeficiency virus coinfection model. The Journal of Clinical Investigation. PMID 34855621 DOI: 10.1172/JCI153090 |
0.343 |
|
| 2021 |
Irvine EB, O'Neil A, Darrah PA, Shin S, Choudhary A, Li W, Honnen W, Mehra S, Kaushal D, Gideon HP, Flynn JL, Roederer M, Seder RA, Pinter A, Fortune S, et al. Robust IgM responses following intravenous vaccination with Bacille Calmette-Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques. Nature Immunology. 22: 1515-1523. PMID 34811542 DOI: 10.1038/s41590-021-01066-1 |
0.321 |
|
| 2021 |
Sharan R, Singh DK, Rengarajan J, Kaushal D. Characterizing Early T Cell Responses in Nonhuman Primate Model of Tuberculosis. Frontiers in Immunology. 12: 706723. PMID 34484203 DOI: 10.3389/fimmu.2021.706723 |
0.353 |
|
| 2021 |
Singh D, Aladyeva E, Das S, Singh B, Esaulova E, Swain A, Ahmed M, Cole J, Moodley C, Mehra S, Schlesinger L, Artyomov M, Khader S, Kaushal D. Myeloid cell interferon responses correlate with clearance of SARS-CoV-2. Research Square. PMID 34282414 DOI: 10.21203/rs.3.rs-664507/v1 |
0.324 |
|
| 2021 |
Cronan MR, Hughes EJ, Brewer WJ, Viswanathan G, Hunt EG, Singh B, Mehra S, Oehlers SH, Gregory SG, Kaushal D, Tobin DM. A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization. Cell. PMID 33761328 DOI: 10.1016/j.cell.2021.02.046 |
0.316 |
|
| 2021 |
Chakraborty P, Bajeli S, Kaushal D, Radotra BD, Kumar A. Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis. Nature Communications. 12: 1606. PMID 33707445 DOI: 10.1038/s41467-021-21748-6 |
0.334 |
|
| 2021 |
Rosa BA, Ahmed M, Singh DK, Choreño-Parra JA, Cole J, Jiménez-Álvarez LA, Rodríguez-Reyna TS, Singh B, Gonzalez O, Carrion R, Schlesinger LS, Martin J, Zúñiga J, Mitreva M, Kaushal D, et al. IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection. Communications Biology. 4: 290. PMID 33674719 DOI: 10.1038/s42003-021-01829-4 |
0.305 |
|
| 2021 |
Ordonez AA, Tucker EW, Anderson CJ, Carter CL, Ganatra S, Kaushal D, Kramnik I, Lin PL, Madigan CA, Mendez S, Rao J, Savic RM, Tobin DM, Walzl G, Wilkinson RJ, et al. Visualizing the dynamics of tuberculosis pathology using molecular imaging. The Journal of Clinical Investigation. 131. PMID 33645551 DOI: 10.1172/JCI145107 |
0.364 |
|
| 2020 |
Esaulova E, Das S, Singh DK, Choreño-Parra JA, Swain A, Arthur L, Rangel-Moreno J, Ahmed M, Singh B, Gupta A, Fernández-López LA, de la Luz Garcia-Hernandez M, Bucsan A, Moodley C, Mehra S, ... ... Kaushal D, et al. The immune landscape in tuberculosis reveals populations linked to disease and latency. Cell Host & Microbe. PMID 33340449 DOI: 10.1016/j.chom.2020.11.013 |
0.396 |
|
| 2020 |
McLaughlin TA, Nizam A, Hayara FO, Ouma GS, Campbell A, Khayumbi J, Ongalo J, Ouma SG, Shah NS, Altman JD, Kaushal D, Rengarajan J, Ernst JD, Blumberg HM, Waller LA, et al. Schistosoma mansoni infection is associated with a higher probability of tuberculosis disease in HIV-infected adults in Kenya. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 33074856 DOI: 10.1097/QAI.0000000000002536 |
0.327 |
|
| 2020 |
Coskun FS, Srivastava S, Raj P, Dozmorov I, Belkaya S, Mehra S, Golden NA, Bucsan AN, Chapagain ML, Wakeland EK, Kaushal D, Gumbo T, van Oers NSC. sncRNA-1 Is a Small Noncoding RNA Produced by in Infected Cells That Positively Regulates Genes Coupled to Oleic Acid Biosynthesis. Frontiers in Microbiology. 11: 1631. PMID 32849337 DOI: 10.3389/Fmicb.2020.01631 |
0.322 |
|
| 2020 |
Rosa BA, Ahmed M, Singh DK, Choreno-Parra JA, Cole J, Jimenez-Alvarez LA, Rodriguez-Reyna TS, Singh B, Golzalez O, Carrion R, Schlesinger LS, Martin J, Zuniga J, Mitreva M, Khader SA, ... Kaushal D, et al. IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 32793903 DOI: 10.1101/2020.08.06.239798 |
0.328 |
|
| 2020 |
Dunlap MD, Prince OA, Rangel-Moreno J, Thomas KA, Scordo JM, Torrelles JB, Cox J, Steyn AJC, Zúñiga J, Kaushal D, Khader SA. Formation of Lung Inducible Bronchus Associated Lymphoid Tissue Is Regulated by Expressed Determinants. Frontiers in Immunology. 11: 1325. PMID 32695111 DOI: 10.3389/Fimmu.2020.01325 |
0.497 |
|
| 2020 |
Shanmugasundaram U, Bucsan AN, Ganatra SR, Ibegbu C, Quezada M, Blair RV, Alvarez X, Velu V, Kaushal D, Rengarajan J. Pulmonary Mycobacterium tuberculosis control associates with CXCR3- and CCR6-expressing antigen-specific Th1 and Th17 cell recruitment. Jci Insight. PMID 32554933 DOI: 10.1172/Jci.Insight.137858 |
0.335 |
|
| 2020 |
Ganatra SR, Bucsan AN, Alvarez X, Kumar S, Chatterjee A, Quezada M, Fish AI, Singh DK, Singh B, Sharan R, Lee TH, Shanmugasundaram U, Velu V, Khader SA, Mehra S, ... ... Kaushal D, et al. Anti-retroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV co-infection model. The Journal of Clinical Investigation. PMID 32544085 DOI: 10.1172/Jci136502 |
0.323 |
|
| 2020 |
Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, Mehra S, Khader SA, Kaushal D. Chronic Immune Activation in TB/HIV Co-infection: (Trends in Microbiology 28, XXX-XXX; 2020). Trends in Microbiology. PMID 32482557 DOI: 10.1016/J.Tim.2020.05.006 |
0.399 |
|
| 2020 |
Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, Mehra S, Khader SA, Kaushal D. Chronic Immune Activation in TB/HIV Co-infection. Trends in Microbiology. PMID 32417227 DOI: 10.1016/J.Tim.2020.03.015 |
0.303 |
|
| 2020 |
Dupont M, Souriant S, Balboa L, Vu Manh TP, Pingris K, Rousset S, Cougoule C, Rombouts Y, Poincloux R, Ben Neji M, Allers C, Kaushal D, Kuroda MJ, Benet S, Martinez-Picado J, et al. Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages. Elife. 9. PMID 32223897 DOI: 10.7554/Elife.52535 |
0.405 |
|
| 2020 |
Scott NR, Swanson RV, Al-Hammadi N, Domingo-Gonzalez R, Rangel-Moreno J, Kriel BA, Bucsan AN, Das S, Ahmed M, Mehra S, Treerat P, Cruz-Lagunas A, Jimenez-Alvarez L, Muñoz-Torrico M, Bobadilla-Lozoya K, ... ... Kaushal D, et al. S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis. The Journal of Clinical Investigation. PMID 32134742 DOI: 10.1172/Jci130546 |
0.328 |
|
| 2020 |
Ahmed M, Thirunavukkarasu S, Rosa BA, Thomas KA, Das S, Rangel-Moreno J, Lu L, Mehra S, Mbandi SK, Thackray LB, Diamond MS, Murphy KM, Means T, Martin J, Kaushal D, et al. Immune correlates of tuberculosis disease and risk translate across species. Science Translational Medicine. 12. PMID 31996462 DOI: 10.1126/Scitranslmed.Aay0233 |
0.428 |
|
| 2020 |
Dupont M, Souriant S, Balboa L, Manh TV, Pingris K, Rousset S, Cougoule C, Rombouts Y, Poincloux R, Neji MB, Allers C, Kaushal D, Kuroda MJ, Benet S, Martinez-Picado J, et al. Author response: Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages Elife. DOI: 10.7554/Elife.52535.Sa2 |
0.391 |
|
| 2019 |
Gautam US, Mehra S, Kumari P, Alvarez X, Niu T, Tyagi JS, Kaushal D. Mycobacterium tuberculosis sensor kinase DosS modulates the autophagosome in a DosR-independent manner. Communications Biology. 2: 349. PMID 31925209 DOI: 10.1038/s42003-019-0594-0 |
0.302 |
|
| 2019 |
Alberto Choreño-Parra J, Bobba S, Rangel-Moreno J, Ahmed M, Mehra S, Rosa B, Martin J, Mitreva M, Kaushal D, Zúñiga J, Khader SA. Mycobacterium tuberculosis HN878 infection induces human-like B cell follicles in mice. The Journal of Infectious Diseases. PMID 31832640 DOI: 10.1093/Infdis/Jiz663 |
0.409 |
|
| 2019 |
Foreman TW, Bucşan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D. Isoniazid and Rifapentine Treatment Eradicates Persistent in Macaques. American Journal of Respiratory and Critical Care Medicine. PMID 31647877 DOI: 10.1164/Rccm.201903-0646Oc |
0.441 |
|
| 2019 |
Bucşan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D. Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection. The Journal of Clinical Investigation. PMID 31479428 DOI: 10.1172/Jci125810 |
0.319 |
|
| 2019 |
Bucsan AN, Mehra S, Khader SA, Kaushal D. The current state of animal models and genomic approaches towards identifying and validating molecular determinants of Mycobacterium tuberculosis infection and tuberculosis disease. Pathogens and Disease. PMID 31381766 DOI: 10.1093/Femspd/Ftz037 |
0.372 |
|
| 2019 |
Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, ... ... Kaushal D, et al. Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. PMID 31168092 DOI: 10.1038/S41586-019-1276-2 |
0.394 |
|
| 2019 |
Bucsan AN, Rout N, Foreman TW, Khader SA, Rengarajan J, Kaushal D. Mucosal-activated invariant T cells do not exhibit significant lung recruitment and proliferation profiles in macaques in response to infection with Mycobacterium tuberculosis CDC1551. Tuberculosis (Edinburgh, Scotland). PMID 31072689 DOI: 10.1016/J.Tube.2019.04.006 |
0.466 |
|
| 2019 |
Elkington P, Lerm M, Kapoor N, Mahon R, Pienaar E, Huh D, Kaushal D, Schlesinger LS. In Vitro Granuloma Models of Tuberculosis: Potential and Challenges. The Journal of Infectious Diseases. PMID 30929010 DOI: 10.1093/Infdis/Jiz020 |
0.376 |
|
| 2019 |
Souriant S, Balboa L, Dupont M, Pingris K, Kviatcovsky D, Cougoule C, Lastrucci C, Bah A, Gasser R, Poincloux R, Raynaud-Messina B, Al Saati T, Inwentarz S, Poggi S, Moraña EJ, ... ... Kaushal D, et al. Tuberculosis Exacerbates HIV-1 Infection through IL-10/STAT3-Dependent Tunneling Nanotube Formation in Macrophages. Cell Reports. 26: 3586-3599.e7. PMID 30917314 DOI: 10.1016/J.Celrep.2019.02.091 |
0.396 |
|
| 2019 |
Corleis B, Bucsan AN, Deruaz M, Vrbanac VD, Lisanti-Park AC, Gates SJ, Linder AH, Paer JM, Olson GS, Bowman BA, Schiff AE, Medoff BD, Tager AM, Luster AD, Khader SA, ... Kaushal D, et al. HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis. Cell Reports. 26: 1409-1418.e5. PMID 30726727 DOI: 10.1016/J.Celrep.2019.01.021 |
0.364 |
|
| 2019 |
Giver CR, Shaw PA, Fletcher H, Kaushal D, Pamela G, Omoyege D, Bisson G, Gumbo T, Wallis R, Waller EK, Kalman D. IMPACT-TB*: A Phase II Trial Assessing the Capacity of Low Dose Imatinib to Induce Myelopoiesis and Enhance Host Anti-Microbial Immunity Against Tuberculosis. *Imatinib Mesylate per Oral As a Clinical Therapeutic for TB Blood. 134: 1050-1050. DOI: 10.1182/Blood-2019-130275 |
0.444 |
|
| 2018 |
Dunlap MD, Howard N, Das S, Scott N, Ahmed M, Prince O, Rangel-Moreno J, Rosa BA, Martin J, Kaushal D, Kaplan G, Mitreva M, Kim KW, Randolph GJ, Khader SA. A novel role for C-C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis. Mucosal Immunology. PMID 30115997 DOI: 10.1038/S41385-018-0071-Y |
0.48 |
|
| 2018 |
Whatney WE, Gandhi NR, Lindestam Arlehamn CS, Nizam A, Wu H, Quezada MJ, Campbell A, Allana S, Kabongo MM, Khayumbi J, Muchiri B, Ongalo J, Tonui J, Sasser LE, Fergus TJ, ... ... Kaushal D, et al. A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in HumanInfection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29540577 DOI: 10.4049/Jimmunol.1701737 |
0.347 |
|
| 2018 |
Kuroda MJ, Sugimoto C, Cai Y, Merino KM, Mehra S, Araínga M, Roy CJ, Midkiff CC, Alvarez X, Didier ES, Kaushal D. High Turnover of Tissue Macrophages Contributes to Tuberculosis Reactivation in Simian Immunodeficiency Virus-Infected Rhesus Macaques. The Journal of Infectious Diseases. PMID 29432596 DOI: 10.1093/Infdis/Jix625 |
0.416 |
|
| 2018 |
Hunter RL, Actor JK, Hwang SA, Khan A, Urbanowski ME, Kaushal D, Jagannath C. Pathogenesis and Animal Models of Post-Primary (Bronchogenic) Tuberculosis, A Review. Pathogens (Basel, Switzerland). 7. PMID 29415434 DOI: 10.3390/Pathogens7010019 |
0.397 |
|
| 2017 |
Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, ... ... Kaushal D, et al. In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255022 DOI: 10.1073/Pnas.1711373114 |
0.503 |
|
| 2017 |
Laddy DJ, Bonavia A, Hanekom WA, Kaushal D, Williams A, Roederer M, Seder RA, Sharpe S, Verreck FAW, Darrah PA. Toward Tuberculosis Vaccine Development: Recommendations for NHP Study Design. Infection and Immunity. PMID 29203540 DOI: 10.1128/Iai.00776-17 |
0.337 |
|
| 2017 |
Foreman TW, Veatch AV, LoBato DN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Lackner AA, Kousoulas KG, Khader SA, Kaushal D, Mehra S. Non-pathological infection of macaques by an attenuated mycobacterial vaccine is not reactivated in the setting of HIV coinfection. The American Journal of Pathology. PMID 28935575 DOI: 10.1016/J.Ajpath.2017.08.014 |
0.39 |
|
| 2017 |
Veatch AV, Kaushal D. Opening Pandora's Box: Mechanisms of Mycobacterium tuberculosis Resuscitation. Trends in Microbiology. PMID 28911979 DOI: 10.1016/J.Tim.2017.08.001 |
0.51 |
|
| 2017 |
Phillips BL, Gautam US, Bucsan AN, Foreman TW, Golden NA, Niu T, Kaushal D, Mehra S. LAG-3 potentiates the survival of Mycobacterium tuberculosis in host phagocytes by modulating mitochondrial signaling in an in-vitro granuloma model. Plos One. 12: e0180413. PMID 28880895 DOI: 10.1371/Journal.Pone.0180413 |
0.463 |
|
| 2017 |
Cheng CY, Gutierrez NM, Marzuki MB, Lu X, Foreman TW, Paleja B, Lee B, Balachander A, Chen J, Tsenova L, Kurepina N, Teng KWW, West K, Mehra S, Zolezzi F, ... ... Kaushal D, et al. Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis. Science Immunology. 2. PMID 28707004 DOI: 10.1126/Sciimmunol.Aaj1789 |
0.51 |
|
| 2017 |
Foreman TW, Mehra S, Lackner AA, Kaushal D. Translational Research in the Nonhuman Primate Model of Tuberculosis. Ilar Journal. 1-9. PMID 28575319 DOI: 10.1093/Ilar/Ilx015 |
0.432 |
|
| 2017 |
Treerat P, Prince O, Cruz-Lagunas A, Muñoz-Torrico M, Salazar-Lezama MA, Selman M, Fallert-Junecko B, Reinhardt TA, Alcorn JF, Kaushal D, Zuñiga J, Rangel-Moreno J, Kolls JK, Khader SA. Novel role for IL-22 in protection during chronic Mycobacterium tuberculosis HN878 infection. Mucosal Immunology. PMID 28247861 DOI: 10.1038/Mi.2017.15 |
0.384 |
|
| 2017 |
Hudock TA, Foreman TW, Bandyopadhyay N, Gautam US, Veatch A, LoBato DN, Gentry KM, Golden NA, Cavigli A, Mueller M, Hwang SA, Hunter RL, Alvarez X, Lackner AA, Bader JS, ... ... Kaushal D, et al. Hypoxia Sensing and Persistence Genes are Expressed During the Intra-granulomatous Survival of M. tuberculosis. American Journal of Respiratory Cell and Molecular Biology. PMID 28135421 DOI: 10.1165/Rcmb.2016-0239Oc |
0.497 |
|
| 2016 |
Veatch AV, Niu T, Caskey J, McGillivray A, Gautam US, Subramanian R, Kousoulas KG, Mehra S, Kaushal D. Sequencing-relative to hybridization-based transcriptomics approaches better define Mycobacterium tuberculosis stress-response regulons. Tuberculosis (Edinburgh, Scotland). PMID 27729257 DOI: 10.1016/J.Tube.2016.09.020 |
0.762 |
|
| 2016 |
Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucşan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, ... ... Kaushal D, et al. CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601645 DOI: 10.1073/Pnas.1611987113 |
0.454 |
|
| 2016 |
Scholl DC, Embers ME, Caskey JR, Kaushal D, Mather TN, Buck WR, Morici LA, Philipp MT. Immunomodulatory effects of tick saliva on dermal cells exposed to Borrelia burgdorferi, the agent of Lyme disease. Parasites & Vectors. 9: 394. PMID 27391120 DOI: 10.1186/S13071-016-1638-7 |
0.322 |
|
| 2015 |
Mothé BR, Lindestam Arlehamn CS, Dow C, Dillon MB, Wiseman RW, Bohn P, Karl J, Golden NA, Gilpin T, Foreman TW, Rodgers MA, Mehra S, Scriba TJ, Flynn JL, Kaushal D, et al. The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans. Tuberculosis (Edinburgh, Scotland). PMID 26526557 DOI: 10.1016/J.Tube.2015.07.005 |
0.414 |
|
| 2015 |
Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, et al. Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis. Nature Communications. 6: 8533. PMID 26460802 DOI: 10.1038/Ncomms9533 |
0.402 |
|
| 2015 |
Venketaraman V, Kaushal D, Saviola B. Mycobacterium tuberculosis. Journal of Immunology Research. 2015: 857598. PMID 26345333 DOI: 10.1155/2015/857598 |
0.345 |
|
| 2015 |
Gautam US, Mehra S, Kaushal D. In-Vivo Gene Signatures of Mycobacterium tuberculosis in C3HeB/FeJ Mice. Plos One. 10: e0135208. PMID 26270051 DOI: 10.1371/Journal.Pone.0135208 |
0.488 |
|
| 2015 |
Levine DM, Dutta NK, Eckels J, Scanga C, Stein C, Mehra S, Kaushal D, Karakousis PC, Salamon H. A tuberculosis ontology for host systems biology. Tuberculosis (Edinburgh, Scotland). 95: 570-4. PMID 26190839 DOI: 10.1016/J.Tube.2015.05.012 |
0.404 |
|
| 2015 |
Mehra S, Foreman TW, Didier PJ, Ahsan MH, Hudock TA, Kissee R, Golden NA, Gautam US, Johnson AM, Alvarez X, Russell-Lodrigue KE, Doyle LA, Roy CJ, Niu T, Blanchard JL, ... ... Kaushal D, et al. The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence. American Journal of Respiratory and Critical Care Medicine. 191: 1185-96. PMID 25730547 DOI: 10.1164/Rccm.201408-1502Oc |
0.478 |
|
| 2015 |
Phillips BL, Mehra S, Ahsan MH, Selman M, Khader SA, Kaushal D. LAG3 expression in active Mycobacterium tuberculosis infections. The American Journal of Pathology. 185: 820-33. PMID 25549835 DOI: 10.1016/J.Ajpath.2014.11.003 |
0.5 |
|
| 2015 |
McGillivray A, Golden NA, Kaushal D. The Mycobacterium tuberculosis Clp gene regulator is required for in vitro reactivation from hypoxia-induced dormancy. The Journal of Biological Chemistry. 290: 2351-67. PMID 25422323 DOI: 10.1074/Jbc.M114.615534 |
0.765 |
|
| 2015 |
Gautam US, McGillivray A, Mehra S, Didier PJ, Midkiff CC, Kissee RS, Golden NA, Alvarez X, Niu T, Rengarajan J, Sherman DR, Kaushal D. DosS Is Required for the Complete Virulence of Mycobacterium tuberculosis in Mice with Classical Granulomatous Lesions. American Journal of Respiratory Cell and Molecular Biology. 52: 708-16. PMID 25322074 DOI: 10.1165/Rcmb.2014-0230Oc |
0.744 |
|
| 2014 |
Dutta NK, McLachlan J, Mehra S, Kaushal D. Humoral and lung immune responses to Mycobacterium tuberculosis infection in a primate model of protection (.) Trials in Vaccinology. 3: 47-51. PMID 25197327 DOI: 10.1016/J.Trivac.2014.02.001 |
0.408 |
|
| 2014 |
Hudock TA, Lackner AA, Kaushal D. Microdissection approaches in tuberculosis research. Journal of Medical Primatology. 43: 294-7. PMID 25164280 DOI: 10.1111/Jmp.12141 |
0.428 |
|
| 2014 |
Luo Q, Mehra S, Golden NA, Kaushal D, Lacey MR. Identification of biomarkers for tuberculosis susceptibility via integrated analysis of gene expression and longitudinal clinical data. Frontiers in Genetics. 5: 240. PMID 25104956 DOI: 10.3389/Fgene.2014.00240 |
0.475 |
|
| 2014 |
Darrah PA, Bolton DL, Lackner AA, Kaushal D, Aye PP, Mehra S, Blanchard JL, Didier PJ, Roy CJ, Rao SS, Hokey DA, Scanga CA, Sizemore DR, Sadoff JC, Roederer M, et al. Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge. Journal of Immunology (Baltimore, Md. : 1950). 193: 1799-811. PMID 25024382 DOI: 10.4049/Jimmunol.1400676 |
0.447 |
|
| 2014 |
Gopal R, Monin L, Slight S, Uche U, Blanchard E, Fallert Junecko BA, Ramos-Payan R, Stallings CL, Reinhart TA, Kolls JK, Kaushal D, Nagarajan U, Rangel-Moreno J, Khader SA. Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection. Plos Pathogens. 10: e1004099. PMID 24831696 DOI: 10.1371/Journal.Ppat.1004099 |
0.419 |
|
| 2014 |
Gautam US, Mehra S, Ahsan MH, Alvarez X, Niu T, Kaushal D. Role of TNF in the altered interaction of dormant Mycobacterium tuberculosis with host macrophages. Plos One. 9: e95220. PMID 24743303 DOI: 10.1371/Journal.Pone.0095220 |
0.499 |
|
| 2014 |
McGillivray A, Golden NA, Gautam US, Mehra S, Kaushal D. The Mycobacterium tuberculosis Rv2745c plays an important role in responding to redox stress. Plos One. 9: e93604. PMID 24705585 DOI: 10.1371/Journal.Pone.0093604 |
0.758 |
|
| 2013 |
Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna KC, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, ... ... Kaushal D, et al. S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis. American Journal of Respiratory and Critical Care Medicine. 188: 1137-46. PMID 24047412 DOI: 10.1164/Rccm.201304-0803Oc |
0.456 |
|
| 2013 |
Roodgar M, Lackner A, Kaushal D, Sankaran S, Dandekar S, Trask JS, Drake C, Smith DG. Expression levels of 10 candidate genes in lung tissue of vaccinated and TB-infected cynomolgus macaques. Journal of Medical Primatology. 42: 161-4. PMID 23802315 DOI: 10.1111/Jmp.12040 |
0.372 |
|
| 2013 |
Mohan M, Kaushal D, Aye PP, Alvarez X, Veazey RS, Lackner AA. Focused examination of the intestinal epithelium reveals transcriptional signatures consistent with disturbances in enterocyte maturation and differentiation during the course of SIV infection. Plos One. 8: e60122. PMID 23593167 DOI: 10.1371/Journal.Pone.0060122 |
0.368 |
|
| 2013 |
Martinez AN, Mehra S, Kaushal D. Role of interleukin 6 in innate immunity to Mycobacterium tuberculosis infection. The Journal of Infectious Diseases. 207: 1253-61. PMID 23359591 DOI: 10.1093/Infdis/Jit037 |
0.478 |
|
| 2013 |
Kaushal D, Bohm RP, Lackner AA. How well do you know your monkeys? Journal of Medical Primatology. 42: 48-9. PMID 23311579 DOI: 10.1111/Jmp.12032 |
0.46 |
|
| 2013 |
Slight SR, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko BA, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart TA, Randall TD, Khader SA. CXCR5⁺ T helper cells mediate protective immunity against tuberculosis. The Journal of Clinical Investigation. 123: 712-26. PMID 23281399 DOI: 10.1172/Jci65728 |
0.498 |
|
| 2013 |
Mehra S, Alvarez X, Didier PJ, Doyle LA, Blanchard JL, Lackner AA, Kaushal D. Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis. The Journal of Infectious Diseases. 207: 1115-27. PMID 23255564 DOI: 10.1093/Infdis/Jis778 |
0.4 |
|
| 2012 |
Kaushal D, Mehra S. Faithful Experimental Models of Human Mycobacterium Tuberculosis Infection. Mycobacterial Diseases : Tuberculosis & Leprosy. 2. PMID 24490123 DOI: 10.4172/2161-1068.1000E108 |
0.437 |
|
| 2012 |
Kaushal D. Eicosanoids, prostaglandins, and the progression of tuberculosis. The Journal of Infectious Diseases. 206: 1803-5. PMID 23033145 DOI: 10.1093/Infdis/Jis611 |
0.527 |
|
| 2012 |
Mohan M, Kaushal D, Aye PP, Alvarez X, Veazey RS, Lackner AA. Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction. Plos One. 7: e34561. PMID 22511950 DOI: 10.1371/Journal.Pone.0034561 |
0.374 |
|
| 2012 |
Kaushal D, Mehra S, Didier PJ, Lackner AA. The non-human primate model of tuberculosis. Journal of Medical Primatology. 41: 191-201. PMID 22429048 DOI: 10.1111/J.1600-0684.2012.00536.X |
0.487 |
|
| 2012 |
Mehra S, Golden NA, Stuckey K, Didier PJ, Doyle LA, Russell-Lodrigue KE, Sugimoto C, Hasegawa A, Sivasubramani SK, Roy CJ, Alvarez X, Kuroda MJ, Blanchard JL, Lackner AA, Kaushal D. The Mycobacterium tuberculosis stress response factor SigH is required for bacterial burden as well as immunopathology in primate lungs. The Journal of Infectious Diseases. 205: 1203-13. PMID 22402035 DOI: 10.1093/Infdis/Jis102 |
0.556 |
|
| 2012 |
Dutta NK, Mehra S, Martinez AN, Alvarez X, Renner NA, Morici LA, Pahar B, Maclean AG, Lackner AA, Kaushal D. The stress-response factor SigH modulates the interaction between Mycobacterium tuberculosis and host phagocytes. Plos One. 7: e28958. PMID 22235255 DOI: 10.1371/Journal.Pone.0028958 |
0.496 |
|
| 2012 |
Roy CJ, Sivasubramani SK, Dutta NK, Mehra S, Golden NA, Killeen S, Talton JD, Hammoud BE, Didier PJ, Kaushal D. Aerosolized gentamicin reduces the burden of tuberculosis in a murine model. Antimicrobial Agents and Chemotherapy. 56: 883-6. PMID 22143521 DOI: 10.1128/Aac.05633-11 |
0.453 |
|
| 2012 |
Roy CJ, Sivasubramani SK, Dutta NK, Mehra S, Golden NA, Killeen S, Talton JD, Hammoud BE, Didier PJ, Kaushal D. Aerosolized gentamicin reduces the burden of tuberculosis in a murine model (Antimicrobial Agents and Chemotherapy (2012) 56, 2 (883-886)) Antimicrobial Agents and Chemotherapy. 56: 1672. DOI: 10.1128/Aac.00190-12 |
0.363 |
|
| 2011 |
Gautam A, Dixit S, Philipp MT, Singh SR, Morici LA, Kaushal D, Dennis VA. Interleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammation. Infection and Immunity. 79: 4876-92. PMID 21947773 DOI: 10.1128/Iai.05451-11 |
0.317 |
|
| 2011 |
Mehra S, Golden NA, Dutta NK, Midkiff CC, Alvarez X, Doyle LA, Asher M, Russell-Lodrigue K, Monjure C, Roy CJ, Blanchard JL, Didier PJ, Veazey RS, Lackner AA, Kaushal D. Reactivation of latent tuberculosis in rhesus macaques by coinfection with simian immunodeficiency virus. Journal of Medical Primatology. 40: 233-43. PMID 21781131 DOI: 10.1111/J.1600-0684.2011.00485.X |
0.475 |
|
| 2010 |
Mehra S, Pahar B, Dutta NK, Conerly CN, Philippi-Falkenstein K, Alvarez X, Kaushal D. Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas. Plos One. 5: e12266. PMID 20824205 DOI: 10.1371/Journal.Pone.0012266 |
0.497 |
|
| 2010 |
Mehra S, Dutta NK, Mollenkopf HJ, Kaushal D. Mycobacterium tuberculosis MT2816 encodes a key stress-response regulator. The Journal of Infectious Diseases. 202: 943-53. PMID 20701538 DOI: 10.1086/654820 |
0.479 |
|
| 2010 |
Dutta NK, Mehra S, Didier PJ, Roy CJ, Doyle LA, Alvarez X, Ratterree M, Be NA, Lamichhane G, Jain SK, Lacey MR, Lackner AA, Kaushal D. Genetic requirements for the survival of tubercle bacilli in primates. The Journal of Infectious Diseases. 201: 1743-52. PMID 20394526 DOI: 10.1086/652497 |
0.511 |
|
| 2010 |
Dutta NK, Mehra S, Kaushal D. A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine. Plos One. 5: e10069. PMID 20386700 DOI: 10.1371/Journal.Pone.0010069 |
0.427 |
|
| 2009 |
Myers TA, Kaushal D, Philipp MT. Microglia are mediators of Borrelia burgdorferi-induced apoptosis in SH-SY5Y neuronal cells. Plos Pathogens. 5: e1000659. PMID 19911057 DOI: 10.1371/Journal.Ppat.1000659 |
0.327 |
|
| 2009 |
Mehra S, Kaushal D. Functional genomics reveals extended roles of the Mycobacterium tuberculosis stress response factor sigmaH. Journal of Bacteriology. 191: 3965-80. PMID 19376862 DOI: 10.1128/Jb.00064-09 |
0.487 |
|
| 2009 |
Bernardino AL, Kaushal D, Philipp MT. The antibiotics doxycycline and minocycline inhibit the inflammatory responses to the Lyme disease spirochete Borrelia burgdorferi. The Journal of Infectious Diseases. 199: 1379-88. PMID 19301981 DOI: 10.1086/597807 |
0.331 |
|
| 2008 |
Izadpanah R, Kaushal D, Kriedt C, Tsien F, Patel B, Dufour J, Bunnell BA. Long-term in vitro expansion alters the biology of adult mesenchymal stem cells. Cancer Research. 68: 4229-38. PMID 18519682 DOI: 10.1158/0008-5472.Can-07-5272 |
0.309 |
|
| 2006 |
Fillon S, Soulis K, Rajasekaran S, Benedict-Hamilton H, Radin JN, Orihuela CJ, El Kasmi KC, Murti G, Kaushal D, Gaber MW, Weber JR, Murray PJ, Tuomanen EI. Platelet-activating factor receptor and innate immunity: uptake of gram-positive bacterial cell wall into host cells and cell-specific pathophysiology. Journal of Immunology (Baltimore, Md. : 1950). 177: 6182-91. PMID 17056547 DOI: 10.4049/Jimmunol.177.9.6182 |
0.318 |
|
| 2006 |
Tekautz TM, Zhu K, Grenet J, Kaushal D, Kidd VJ, Lahti JM. Evaluation of IFN-gamma effects on apoptosis and gene expression in neuroblastoma--preclinical studies. Biochimica Et Biophysica Acta. 1763: 1000-10. PMID 16979248 DOI: 10.1016/J.Bbamcr.2006.06.014 |
0.349 |
|
| 2006 |
Obert C, Sublett J, Kaushal D, Hinojosa E, Barton T, Tuomanen EI, Orihuela CJ. Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease. Infection and Immunity. 74: 4766-77. PMID 16861665 DOI: 10.1128/Iai.00316-06 |
0.348 |
|
| 2005 |
Haas W, Kaushal D, Sublett J, Obert C, Tuomanen EI. Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae. Journal of Bacteriology. 187: 8205-10. PMID 16291696 DOI: 10.1128/Jb.187.23.8205-8210.2005 |
0.387 |
|
| 2004 |
Haas W, Sublett J, Kaushal D, Tuomanen EI. Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance. Journal of Bacteriology. 186: 8463-71. PMID 15576796 DOI: 10.1128/Jb.186.24.8463-8471.2004 |
0.354 |
|
| 2004 |
Orihuela CJ, Radin JN, Sublett JE, Gao G, Kaushal D, Tuomanen EI. Microarray analysis of pneumococcal gene expression during invasive disease. Infection and Immunity. 72: 5582-96. PMID 15385455 DOI: 10.1128/Iai.72.10.5582-5596.2004 |
0.402 |
|
| 2004 |
Geiman DE, Kaushal D, Ko C, Tyagi S, Manabe YC, Schroeder BG, Fleischmann RD, Morrison NE, Converse PJ, Chen P, Bishai WR. Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis. Infection and Immunity. 72: 1733-45. PMID 14977982 DOI: 10.1128/Iai.72.3.1733-1745.2004 |
0.46 |
|
| 2002 |
Kaushal D, Schroeder BG, Tyagi S, Yoshimatsu T, Scott C, Ko C, Carpenter L, Mehrotra J, Manabe YC, Fleischmann RD, Bishai WR. Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH. Proceedings of the National Academy of Sciences of the United States of America. 99: 8330-5. PMID 12060776 DOI: 10.1073/Pnas.102055799 |
0.524 |
|
| 1998 |
DasGupta SK, Jain S, Kaushal D, Tyagi AK. Expression systems for study of mycobacterial gene regulation and development of recombinant BCG vaccines. Biochemical and Biophysical Research Communications. 246: 797-804. PMID 9618292 DOI: 10.1006/Bbrc.1998.8724 |
0.422 |
|
| 1997 |
Jain S, Kaushal D, DasGupta SK, Tyagi AK. Construction of shuttle vectors for genetic manipulation and molecular analysis of mycobacteria. Gene. 190: 37-44. PMID 9185847 DOI: 10.1016/S0378-1119(96)00746-9 |
0.361 |
|
| 1996 |
Bashyam MD, Kaushal D, Dasgupta SK, Tyagi AK. A study of mycobacterial transcriptional apparatus: identification of novel features in promoter elements. Journal of Bacteriology. 178: 4847-53. PMID 8759847 DOI: 10.1128/Jb.178.16.4847-4853.1996 |
0.312 |
|
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