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Jeno M. Scharer - Publications

Affiliations: 
University of Waterloo, Waterloo, ON, Canada 
Area:
Chemical Engineering, Molecular Biology
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Aghamohseni H, Ohadi K, Spearman M, Krahn N, Moo-Young M, Scharer JM, Butler M, Budman HM. Effects of nutrient levels and average culture pH on the glycosylation pattern of camelid-humanized monoclonal antibody. Journal of Biotechnology. 186: 98-109. PMID 25014402 DOI: 10.1016/J.Jbiotec.2014.05.024  0.378
2014 Naderi S, Nikdel A, Meshram M, McConkey B, Ingalls B, Budman H, Scharer J. Modeling of cell culture damage and recovery leads to increased antibody and biomass productivity in CHO cell cultures. Biotechnology Journal. 9: 1152-63. PMID 24852214 DOI: 10.1002/Biot.201300287  0.421
2014 Westbrook A, Scharer J, Moo-Young M, Oosterhuis N, Perry Chou C. Application of a two-dimensional disposable rocking bioreactor to bacterial cultivation for recombinant protein production Biochemical Engineering Journal. 88: 154-161. DOI: 10.1016/J.Bej.2014.04.011  0.345
2013 Meshram M, Naderi S, McConkey B, Ingalls B, Scharer J, Budman H. Modeling the coupled extracellular and intracellular environments in mammalian cell culture. Metabolic Engineering. 19: 57-68. PMID 23810769 DOI: 10.1016/J.Ymben.2013.06.002  0.397
2012 Orr V, Scharer J, Moo-Young M, Honeyman CH, Fenner D, Crossley L, Suen SY, Chou CP. Integrated development of an effective bioprocess for extracellular production of penicillin G acylase in Escherichia coli and its subsequent one-step purification Journal of Biotechnology. 161: 19-26. PMID 22728392 DOI: 10.1016/J.Jbiotec.2012.05.013  0.397
2012 Orr V, Scharer J, Moo-Young M, Honeyman CH, Fenner D, Crossley L, Suen SY, Chou CP. Simultaneous clarification of Escherichia coli culture and purification of extracellularly produced penicillin G acylase using tangential flow filtration and anion-exchange membrane chromatography (TFF-AEMC) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 900: 71-78. PMID 22709629 DOI: 10.1016/J.Jchromb.2012.05.039  0.343
2012 Meshram M, Naderi S, McConkey B, Budman H, Scharer J, Ingalls B. Population-based modeling of the progression of apoptosis in mammalian cell culture. Biotechnology and Bioengineering. 109: 1193-204. PMID 22125113 DOI: 10.1002/Bit.24392  0.369
2011 Wei YY, Naderi S, Meshram M, Budman H, Scharer JM, Ingalls BP, McConkey BJ. Proteomics analysis of chinese hamster ovary cells undergoing apoptosis during prolonged cultivation. Cytotechnology. 63: 663-77. PMID 21853334 DOI: 10.1007/S10616-011-9385-2  0.344
2011 Naderi S, Meshram M, Wei C, McConkey B, Ingalls B, Budman H, Scharer J. Development of a mathematical model for evaluating the dynamics of normal and apoptotic Chinese hamster ovary cells. Biotechnology Progress. 27: 1197-205. PMID 21618458 DOI: 10.1002/Btpr.647  0.374
2011 Dutton RL, Scharer JM, Moo-Young M. Hybridoma growth and productivity: effects of conditioned medium and of inoculum size. Cytotechnology. 29: 1-10. PMID 19003332 DOI: 10.1023/A:1008060802286  0.395
2011 Sriphochanart W, Skolpap W, Scharer JM, Moo-Young M, Douglas PL. Effect of amino acid requirements on the growth and lactic acid production of Pediococcus acidilactici culture African Journal of Microbiology Research. 5: 3815-3822. DOI: 10.5897/Ajmr11.721  0.33
2011 Meshram M, Naderi S, Wei Y, McConkey B, Ingalls B, Budman H, Scharer J. Dynamic Modeling of Apoptosis and its Interaction with Cell Growth in Mammalian Cell Culture Ifac Proceedings Volumes. 44: 9691-9696. DOI: 10.3182/20110828-6-It-1002.02462  0.358
2011 Nowruzi K, Elkamel A, Scharer JM, Cossar D, Moo-Young M. Metabolic flux-based optimisation of recombinant human interleukin-3 expression by Streptomyces lividans 66 The Canadian Journal of Chemical Engineering. 89: 879-888. DOI: 10.1002/Cjce.20447  0.304
2010 Meshram M, Wei Y, Naderi S, McConkey B, Ingalls B, Budman H, Scharer J. Modeling the progression of apoptosis in Chinese Hamster Ovary cells Ifac Proceedings Volumes. 43: 467-472. DOI: 10.3182/20100707-3-Be-2012.0026  0.315
2010 Naderi S, Meshram M, Wei C, McConkey B, Ingalls B, Budman H, Scharer J. Metabolic flux and nutrient uptake modeling of normal and apoptotic CHO cells Ifac Proceedings Volumes. 43: 395-400. DOI: 10.3182/20100707-3-Be-2012.0005  0.369
2009 Gheshlaghi R, Scharer JM, Moo-Young M, Chou CP. Metabolic pathways of clostridia for producing butanol. Biotechnology Advances. 27: 764-781. PMID 19539744 DOI: 10.1016/J.Biotechadv.2009.06.002  0.332
2009 Dorka P, Fischer C, Budman H, Scharer JM. Metabolic flux-based modeling of mAb production during batch and fed-batch operations. Bioprocess and Biosystems Engineering. 32: 183-96. PMID 18560901 DOI: 10.1007/S00449-008-0236-2  0.358
2008 Gheshlaghi R, Scharer J, Moo-Young M, Douglas P. Application of statistical design for the optimization of amino acid separation by reverse-phase HPLC Analytical Biochemistry. 383: 93-102. PMID 18722994 DOI: 10.1016/J.Ab.2008.07.032  0.314
2008 Nowruzi K, Elkamel A, Scharer JM, Cossar D, Moo-Young M. Development of a minimal defined medium for recombinant human interleukin-3 production by Streptomyces lividans 66. Biotechnology and Bioengineering. 99: 214-22. PMID 17615562 DOI: 10.1002/Bit.21566  0.322
2008 Skolpap W, Nuchprayoon S, Scharer JM, Grisdanurak N, Douglas PL, Moo-Young M. Fed-batch optimization of α-amylase and protease-producing Bacillus subtilis using genetic algorithm and particle swarm optimization Chemical Engineering Science. 63: 4090-4099. DOI: 10.1016/J.Ces.2008.05.016  0.315
2008 Skolpap W, Nuchprayoon S, Scharer JM, Grisdanurak N, Douglas PL, Moo-Young M. Fed-batch optimization of recombinant α-amylase production by Bacillus subtilis using a modified Markov chain Monte Carlo technique Korean Journal of Chemical Engineering. 25: 646-655. DOI: 10.1007/S11814-008-0107-1  0.327
2007 Gheshlaghi R, Scharer JM, Moo-Young M, Douglas PL. Metabolic flux analysis for optimizing the specific growth rate of recombinant Aspergillus niger. Bioprocess and Biosystems Engineering. 30: 397-418. PMID 17629794 DOI: 10.1007/S00449-007-0136-X  0.374
2007 Skolpap W, Nuchprayoon S, Scharer JM, Moo-Young M. Parametric analysis of metabolic fluxes of alpha-amylase and protease-producing Bacillus subtilis. Bioprocess and Biosystems Engineering. 30: 337-48. PMID 17514498 DOI: 10.1007/S00449-007-0130-3  0.303
2007 Gao J, Gorenflo VM, Scharer JM, Budman HM. Dynamic metabolic modeling for a MAB bioprocess. Biotechnology Progress. 23: 168-81. PMID 17269685 DOI: 10.1021/Bp060089Y  0.375
2007 De Alwis DM, Dutton RL, Scharer J, Moo-Young M. Statistical methods in media optimization for batch and fed-batch animal cell culture. Bioprocess and Biosystems Engineering. 30: 107-13. PMID 17242929 DOI: 10.1007/S00449-006-0107-7  0.375
2006 Dutton RL, Scharer J, Moo-Young M. Cell cycle phase dependent productivity of a recombinant Chinese hamster ovary cell line. Cytotechnology. 52: 55-69. PMID 19002865 DOI: 10.1007/S10616-006-9041-4  0.363
2006 Snyder CJ, Asghar M, Scharer JM, Legge RL. Biodegradation kinetics of 2,4,6-trichlorophenol by an acclimated mixed microbial culture under aerobic conditions. Biodegradation. 17: 535-44. PMID 16489415 DOI: 10.1007/S10532-005-9024-8  0.379
2006 Xu Y, Rosenkranz S, Weng CL, Scharer JM, Moo-Young M, Chou CP. Characterization of the T7 promoter system for expressing penicillin acylase in Escherichia coli. Applied Microbiology and Biotechnology. 72: 529-36. PMID 16411086 DOI: 10.1007/S00253-005-0293-2  0.34
2005 Gheshlaghi R, Scharer J, Moo-Young M, Douglas P. Medium optimization for hen egg white lysozyme production by recombinant Aspergillus niger using statistical methods. Biotechnology and Bioengineering. 90: 754-760. PMID 15806549 DOI: 10.1002/Bit.20474  0.315
2004 Skolpap W, Scharer JM, Douglas PL, Moo-Young M. Fed-batch optimization of alpha-amylase and protease-producing Bacillus subtilis using Markov chain methods. Biotechnology and Bioengineering. 86: 706-17. PMID 15137083 DOI: 10.1002/Bit.20079  0.336
2004 Bols NC, Scharer JM, Phillips HA, Moo-Young M. Media for hybridoma growth and monoclonal antibody production. Biotechnology Advances. 6: 169-82. PMID 14541214 DOI: 10.1016/0734-9750(88)90003-1  0.365
2001 Yun S, Yahya ARM, Malten M, Cossar D, Anderson WA, Scharer JM, Moo-Young M. Peptidases affecting recombinant protein production by Streptomyces lividans. Canadian Journal of Microbiology. 47: 1137-1140. DOI: 10.1139/W01-120  0.368
2001 Yun SI, Yahya ARM, Cossar D, Anderson WA, Scharer JM, Moo-Young M. Temperature downshift increases recombinant cytokine titer in Streptomyces lividans fermentation Biotechnology Letters. 23: 1903-1905. DOI: 10.1023/A:1013798129637  0.343
2001 Skolpap W, Scharer J, Douglas P, Moo-Young M. Metabolic Flux Estimation for α-Amylase and Protease Synthesis by Bacillus Subtilis Ifac Proceedings Volumes. 34: 125-130. DOI: 10.1016/S1474-6670(17)34207-6  0.336
2001 Nor ZM, Tamer MI, Scharer JM, Moo-Young M, Jervis EJ. Automated fed-batch culture of Kluyveromyces fragilis based on a novel method for on-line estimation of cell specific growth rate Biochemical Engineering Journal. 9: 221-231. DOI: 10.1016/S1369-703X(01)00147-4  0.381
2001 Rouf SA, Douglas PL, Moo-Young M, Scharer JM. Computer simulation for large scale bioprocess design Biochemical Engineering Journal. 8: 229-234. DOI: 10.1016/S1369-703X(01)00112-7  0.341
2000 Rouf SA, Moo-Young M, Scharer JM, Douglas PL. Single versus multiple bioreactor scale-up: economy for high-value products. Biochemical Engineering Journal. 6: 25-31. PMID 10908865 DOI: 10.1016/S1369-703X(00)00066-8  0.303
1998 Dutton RL, Scharer JM, Moo-Young M. Descriptive parameter evaluation in mammalian cell culture. Cytotechnology. 26: 139-152. PMID 22358552 DOI: 10.1023/A:1007940119503  0.399
1998 Rouf S, Douglas P, Moo-young M, Scharer J. Computer Aided Design of Large Scale Integrated Bioprocess Ifac Proceedings Volumes. 31: 141-146. DOI: 10.1016/S1474-6670(17)40174-1  0.347
1997 Zhang Z, Scharer J, Moo-Young M. Protein production using recombinant yeast in an immobilized-cell-film airlift bioreactor. Biotechnology and Bioengineering. 55: 241-251. PMID 18636482 DOI: 10.1002/(Sici)1097-0290(19970720)55:2<241::Aid-Bit1>3.0.Co;2-I  0.39
1997 Zhang Z, Scharer JM, Moo-Young M. Plasmid instability kinetics in continuous culture of a recombinant Saccharomyces cerevisiae in airlift bioreactor Journal of Biotechnology. 55: 31-41. PMID 9226960 DOI: 10.1016/S0168-1656(97)00057-6  0.347
1993 Phillips HA, Scharer JM, Bols NC, Moo-Young M. Design and performance of a trickle-bed bioreactor with immobilized hybridoma cells. Cytotechnology. 9: 29-40. PMID 1369178 DOI: 10.1007/Bf02521729  0.349
1992 Chao S, Scharer JM, Moo-Young M. A general method for biological parameter estimation Biotechnology Techniques. 6: 495-500. DOI: 10.1007/Bf02447820  0.335
1988 Wang E, Overgaard SE, Scharer JM, Bols NC, Moo-Young M. Occlusion immobilization of hybridoma cells in chitosan Biotechnology Techniques. 2: 133-136. DOI: 10.1007/Bf01876164  0.323
1987 Bhadra A, Scharer JM, Moo-Young M. Methanogenesis from volatile fatty acids in downflow stationary fixed-film reactor. Biotechnology and Bioengineering. 30: 314-319. PMID 18581314 DOI: 10.1002/Bit.260300223  0.33
1987 Phillips HA, Scharer JM, Bols NC, Moo-Young M. Effect of oxygen on antibody productivity in hybridoma culture Biotechnology Letters. 9: 745-750. DOI: 10.1007/Bf01028277  0.336
1986 Bhadra A, Scharer JM, Moo-Young M, Zelin S. Enhanced anaerobic digestion of cellulose by intermittent floc-dispersion at 55�C Biotechnology Letters. 8: 209-212. DOI: 10.1007/Bf01029382  0.326
1981 Scharer JM, Moo-Young M, Fujita M. Methane production by anaerobic digestion of animal manures Biotechnology Letters. 3: 231-237. DOI: 10.1007/Bf00154650  0.311
1973 Elmayergi H, Scharer JM, Moo-Young M. Effects of polymer additives on fermentation parameters in a culture ofA. niger Biotechnology and Bioengineering. 15: 845-859. DOI: 10.1002/Bit.260150503  0.347
1968 Scharer JM, Klein F, Lincoln RE. Growth and metabolism of live vaccine strain of Pasteurella tularensis. Applied and Environmental Microbiology. 16: 855-861. DOI: 10.1128/Aem.16.6.855-861.1968  0.301
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