Anurag Tandon, PhD - Publications

Centre for Research in Neurodegenerative Diseases University of Toronto, Toronto, ON, Canada 
Parkinson's disease

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lautenschläger J, Stephens AD, Fusco G, Ströhl F, Curry N, Zacharopoulou M, Michel CH, Laine R, Nespovitaya N, Fantham M, Pinotsi D, Zago W, Fraser P, Tandon A, St George-Hyslop P, et al. C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction. Nature Communications. 9: 712. PMID 29459792 DOI: 10.1038/s41467-018-03111-4  0.4
2015 Samuel F, Flavin WP, Iqbal S, Pacelli C, Sri Renganathan SD, Trudeau LE, Campbell EM, Fraser PE, Tandon A. Effects of Serine 129 phosphorylation on α-synuclein aggregation, membrane association, and internalization. The Journal of Biological Chemistry. PMID 26719332 DOI: 10.1074/jbc.M115.705095  0.4
2014 Kanemoto S, Griffin J, Markham-Coultes K, Aubert I, Tandon A, George-Hyslop PS, Fraser PE. Proliferation, differentiation and amyloid-β production in neural progenitor cells isolated from TgCRND8 mice. Neuroscience. 261: 52-9. PMID 24361736 DOI: 10.1016/j.neuroscience.2013.12.021  0.4
2013 Visanji NP, Collingwood JF, Finnegan ME, Tandon A, House E, Hazrati LN. Iron deficiency in parkinsonism: region-specific iron dysregulation in Parkinson's disease and multiple system atrophy. Journal of Parkinson's Disease. 3: 523-37. PMID 24113558 DOI: 10.3233/JPD-130197  0.4
2013 Chen RH, Wislet-Gendebien S, Samuel F, Visanji NP, Zhang G, Marsilio D, Langman T, Fraser PE, Tandon A. α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity. The Journal of Biological Chemistry. 288: 7438-49. PMID 23344955 DOI: 10.1074/jbc.M112.439497  0.4
2012 Fauvet B, Fares MB, Samuel F, Dikiy I, Tandon A, Eliezer D, Lashuel HA. Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein. The Journal of Biological Chemistry. 287: 28243-62. PMID 22718772 DOI: 10.1074/jbc.M112.383711  0.4
2012 Zhang G, Tandon A. Quantitative assessment on the cloning efficiencies of lentiviral transfer vectors with a unique clone site. Scientific Reports. 2: 1-8. PMID 22629482 DOI: 10.1038/srep00415  0.4
2011 Visanji NP, Wislet-Gendebien S, Oschipok LW, Zhang G, Aubert I, Fraser PE, Tandon A. Effect of Ser-129 phosphorylation on interaction of α-synuclein with synaptic and cellular membranes. The Journal of Biological Chemistry. 286: 35863-73. PMID 21849493 DOI: 10.1074/jbc.M111.253450  0.4
2010 Dyllick-Brenzinger M, D'Souza CA, Dahlmann B, Kloetzel PM, Tandon A. Reciprocal effects of alpha-synuclein overexpression and proteasome inhibition in neuronal cells and tissue. Neurotoxicity Research. 17: 215-27. PMID 19653055 DOI: 10.1007/s12640-009-9094-1  0.4
2009 Cherra SJ, Dagda RK, Tandon A, Chu CT. Mitochondrial autophagy as a compensatory response to PINK1 deficiency. Autophagy. 5: 1213-4. PMID 19786829 DOI: 10.4161/auto.5.8.10050  0.4
2009 Dagda RK, Cherra SJ, Kulich SM, Tandon A, Park D, Chu CT. Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. The Journal of Biological Chemistry. 284: 13843-55. PMID 19279012 DOI: 10.1074/jbc.M808515200  0.4
2008 Wislet-Gendebien S, Visanji NP, Whitehead SN, Marsilio D, Hou W, Figeys D, Fraser PE, Bennett SA, Tandon A. Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors. Bmc Neuroscience. 9: 92. PMID 18808659 DOI: 10.1186/1471-2202-9-92  0.4
2008 Haque ME, Thomas KJ, D'Souza C, Callaghan S, Kitada T, Slack RS, Fraser P, Cookson MR, Tandon A, Park DS. Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proceedings of the National Academy of Sciences of the United States of America. 105: 1716-21. PMID 18218782 DOI: 10.1073/pnas.0705363105  0.4
2007 Inamdar NN, Arulmozhi DK, Tandon A, Bodhankar SL. Parkinson's disease: genetics and beyond. Current Neuropharmacology. 5: 99-113. PMID 18615181 DOI: 10.2174/157015907780866893  0.4
2007 Mathur BN, Neely MD, Dyllick-Brenzinger M, Tandon A, Deutch AY. Systemic administration of a proteasome inhibitor does not cause nigrostriatal dopamine degeneration. Brain Research. 1168: 83-9. PMID 17706185 DOI: 10.1016/j.brainres.2007.06.076  0.4
2006 Wislet-Gendebien S, D'Souza C, Kawarai T, St George-Hyslop P, Westaway D, Fraser P, Tandon A. Cytosolic proteins regulate alpha-synuclein dissociation from presynaptic membranes. The Journal of Biological Chemistry. 281: 32148-55. PMID 16926154 DOI: 10.1074/jbc.M605965200  0.4
2006 Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, et al. TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature. 440: 1208-12. PMID 16641999 DOI: 10.1038/nature04667  0.4
2005 Petit A, Kawarai T, Paitel E, Sanjo N, Maj M, Scheid M, Chen F, Gu Y, Hasegawa H, Salehi-Rad S, Wang L, Rogaeva E, Fraser P, Robinson B, St George-Hyslop P, ... Tandon A, et al. Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. The Journal of Biological Chemistry. 280: 34025-32. PMID 16079129 DOI: 10.1074/jbc.M505143200  0.4
2004 Rogaeva E, Johnson J, Lang AE, Gulick C, Gwinn-Hardy K, Kawarai T, Sato C, Morgan A, Werner J, Nussbaum R, Petit A, Okun MS, McInerney A, Mandel R, Groen JL, ... ... Tandon A, et al. Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease. Archives of Neurology. 61: 1898-904. PMID 15596610 DOI: 10.1001/archneur.61.12.1898  0.4
2004 Jo E, Darabie AA, Han K, Tandon A, Fraser PE, McLaurin J. alpha-Synuclein-synaptosomal membrane interactions: implications for fibrillogenesis. European Journal of Biochemistry / Febs. 271: 3180-9. PMID 15265037 DOI: 10.1111/j.1432-1033.2004.04250.x  0.4
2003 Tandon A, Yu H, Wang L, Rogaeva E, Sato C, Chishti MA, Kawarai T, Hasegawa H, Chen F, Davies P, Fraser PE, Westaway D, St George-Hyslop PH. Brain levels of CDK5 activator p25 are not increased in Alzheimer's or other neurodegenerative diseases with neurofibrillary tangles. Journal of Neurochemistry. 86: 572-81. PMID 12859671 DOI: 10.1046/j.1471-4159.2003.01865.x  0.4
2003 Chen F, Tandon A, Sanjo N, Gu YJ, Hasegawa H, Arawaka S, Lee FJ, Ruan X, Mastrangelo P, Erdebil S, Wang L, Westaway D, Mount HT, Yankner B, Fraser PE, et al. Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain. The Journal of Biological Chemistry. 278: 19974-9. PMID 12646573 DOI: 10.1074/jbc.M210049200  0.4
2003 Gu Y, Chen F, Sanjo N, Kawarai T, Hasegawa H, Duthie M, Li W, Ruan X, Luthra A, Mount HT, Tandon A, Fraser PE, St George-Hyslop P. APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes. The Journal of Biological Chemistry. 278: 7374-80. PMID 12471034 DOI: 10.1074/jbc.M209499200  0.4
2002 Arawaka S, Hasegawa H, Tandon A, Janus C, Chen F, Yu G, Kikuchi K, Koyama S, Kato T, Fraser PE, St George-Hyslop P. The levels of mature glycosylated nicastrin are regulated and correlate with gamma-secretase processing of amyloid beta-precursor protein. Journal of Neurochemistry. 83: 1065-71. PMID 12437577 DOI: 10.1046/j.1471-4159.2002.01207.x  0.4
2002 Tandon A, Fraser P. The presenilins. Genome Biology. 3: reviews3014. PMID 12429067  0.4
2002 Yang DS, Tandon A, Chen F, Yu G, Yu H, Arawaka S, Hasegawa H, Duthie M, Schmidt SD, Ramabhadran TV, Nixon RA, Mathews PM, Gandy SE, Mount HT, St George-Hyslop P, et al. Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins. The Journal of Biological Chemistry. 277: 28135-42. PMID 12032140 DOI: 10.1074/jbc.M110871200  0.4
2001 Rogaeva E, Tandon A, St George-Hyslop PH. Genetic markers in the diagnosis of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 3: 293-304. PMID 12214050  0.4
2001 Chen F, Yu G, Arawaka S, Nishimura M, Kawarai T, Yu H, Tandon A, Supala A, Song YQ, Rogaeva E, Milman P, Sato C, Yu C, Janus C, Lee J, et al. Nicastrin binds to membrane-tethered Notch. Nature Cell Biology. 3: 751-4. PMID 11483961 DOI: 10.1038/35087069  0.4
2000 Yu G, Chen F, Nishimura M, Steiner H, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Holmes E, Zhang DM, Milman P, Fraser P, Haass C, et al. Mutation of conserved aspartates affect maturation of presenilin 1 and presenilin 2 complexes. Acta Neurologica Scandinavica. Supplementum. 176: 6-11. PMID 11261807  0.4
2000 Zhang DM, Levitan D, Yu G, Nishimura M, Chen F, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Liang Y, Holmes E, Milman P, Sato C, et al. Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans. Neuroreport. 11: 3227-30. PMID 11043553  0.4
2000 Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, et al. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 407: 48-54. PMID 10993067 DOI: 10.1038/35024009  0.4
2000 Tandon A, Rogaeva E, Mullan M, St George-Hyslop PH. Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins. Current Opinion in Neurology. 13: 377-84. PMID 10970053 DOI: 10.1097/00019052-200008000-00003  0.4
2000 Chen F, Yang DS, Petanceska S, Yang A, Tandon A, Yu G, Rozmahel R, Ghiso J, Nishimura M, Zhang DM, Kawarai T, Levesque G, Mills J, Levesque L, Song YQ, et al. Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells. The Journal of Biological Chemistry. 275: 36794-802. PMID 10962005 DOI: 10.1074/jbc.M006986200  0.4
2000 Yu G, Chen F, Nishimura M, Steiner H, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Holmes E, Zhang DM, Milman P, Fraser PE, Haass C, et al. Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes. The Journal of Biological Chemistry. 275: 27348-53. PMID 10856299 DOI: 10.1074/jbc.M002982200  0.4
1998 Tandon A, Tan PK, Bannykh S, Banerjee A, Balch WE. Neurotransmitter release from semi-intact synaptosomes. Methods (San Diego, Calif.). 16: 198-203. PMID 9790866 DOI: 10.1006/meth.1998.0667  0.4
1998 Tandon A, Bannykh S, Kowalchyk JA, Banerjee A, Martin TF, Balch WE. Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes. Neuron. 21: 147-54. PMID 9697859 DOI: 10.1016/S0896-6273(00)80522-X  0.4
1998 D'Adamo P, Menegon A, Lo Nigro C, Grasso M, Gulisano M, Tamanini F, Bienvenu T, Gedeon AK, Oostra B, Wu SK, Tandon A, Valtorta F, Balch WE, Chelly J, Toniolo D. Mutations in GDI1 are responsible for X-linked non-specific mental retardation. Nature Genetics. 19: 134-9. PMID 9620768 DOI: 10.1038/487  0.4
1996 Tandon A, Bachoo M, Weldon P, Polosa C, Collier B. Effects of colchicine application to preganglionic axons on choline acetyltransferase activity and acetylcholine content and release in the superior cervical ganglion. Journal of Neurochemistry. 66: 1033-41. PMID 8769864  0.4
1996 Schalk I, Zeng K, Wu SK, Stura EA, Matteson J, Huang M, Tandon A, Wilson IA, Balch WE. Structure and mutational analysis of Rab GDP-dissociation inhibitor. Nature. 381: 42-8. PMID 8609986 DOI: 10.1038/381042a0  0.4
1995 Tandon A, Collier B. Increased acetylcholine content induced by antidromic stimulation of a sympathetic ganglion: a possible retrograde action of adenosine. Journal of Neurochemistry. 65: 2116-23. PMID 7595497  0.4
1994 Tandon A, Collier B. The role of endogenous adenosine in a poststimulation increase in the acetylcholine content of a sympathetic ganglion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4927-36. PMID 8046461  0.4
1993 Tandon A, Collier B. Increased acetylcholine content induced by adenosine in a sympathetic ganglion and its subsequent mobilization by electrical stimulation. Journal of Neurochemistry. 60: 2124-33. PMID 8492121  0.4
1993 Collier B, Tandon A, Prado MA, Bachoo M. Storage and release of acetylcholine in a sympathetic ganglion. Progress in Brain Research. 98: 183-9. PMID 8248507  0.4
1991 Tandon A, Collier B, Zhang ZW, Feltz P. Acetylcholine synthesis in a primary culture of porcine intermediate lobe cells. Journal of Neuroendocrinology. 3: 273-7. PMID 19215464 DOI: 10.1111/j.1365-2826.1991.tb00275.x  0.4
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