Hazem E. Ghoneim, Ph.D. - Publications

Affiliations: 
2013 Microbial Pathogenesis, Immunology, and Inflammation University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Microbiology Biology, Immunology, Virology Biology

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Read KA, Jones DM, Pokhrel S, Hales EDS, Varkey A, Tuazon JA, Eisele CD, Abdouni O, Saadey A, Leonard MR, Warren RT, Powell MD, Boss JM, Hemann EA, Yount JS, ... ... Ghoneim HE, et al. Aiolos represses CD4 T cell cytotoxic programming via reciprocal regulation of T transcription factors and IL-2 sensitivity. Nature Communications. 14: 1652. PMID 36964178 DOI: 10.1038/s41467-023-37420-0  0.336
2023 Soerens AG, Künzli M, Quarnstrom CF, Scott MC, Swanson L, Locquiao JJ, Ghoneim HE, Zehn D, Youngblood B, Vezys V, Masopust D. Functional T cells are capable of supernumerary cell division and longevity. Nature. PMID 36653453 DOI: 10.1038/s41586-022-05626-9  0.354
2022 Saadey AA, Yousif A, Osborne N, Shahinfar R, Chen YL, Laster B, Rajeev M, Bauman P, Webb A, Ghoneim HE. Rebalancing TGFβ1/BMP signals in exhausted T cells unlocks responsiveness to immune checkpoint blockade therapy. Nature Immunology. PMID 36543960 DOI: 10.1038/s41590-022-01384-y  0.343
2020 LeMessurier KS, Rooney R, Ghoneim HE, Liu B, Li K, Smallwood HS, Samarasinghe AE. Influenza A virus directly modulates mouse eosinophil responses. Journal of Leukocyte Biology. PMID 32386457 DOI: 10.1002/Jlb.4Ma0320-343R  0.52
2020 Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, et al. Beta cell-specific CD8 T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nature Immunology. PMID 32231298 DOI: 10.1038/S41590-020-0633-5  0.375
2020 Fonseca R, Beura LK, Quarnstrom CF, Ghoneim HE, Fan Y, Zebley CC, Scott MC, Fares-Frederickson NJ, Wijeyesinghe S, Thompson EA, Borges da Silva H, Vezys V, Youngblood B, Masopust D. Developmental plasticity allows outside-in immune responses by resident memory T cells. Nature Immunology. PMID 32066954 DOI: 10.1038/S41590-020-0607-7  0.384
2019 Alfei F, Kanev K, Hofmann M, Wu M, Ghoneim HE, Roelli P, Utzschneider DT, von Hösslin M, Cullen JG, Fan Y, Eisenberg V, Wohlleber D, Steiger K, Merkler D, Delorenzi M, et al. TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection. Nature. PMID 31207605 DOI: 10.1038/S41586-019-1326-9  0.482
2019 Ghoneim HE, Fan Y, Moustaki A, Abdelsamed H, Dash P, Dogra P, Carter R, Awad W, Neale G, Thomas P, Youngblood B. Abstract A189: Targeting T-cell epigenetic programs to enhance the efficacy of immune checkpoint blockade Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A189  0.43
2018 Ghoneim HE, Fan Y, Moustaki A, Abdelsamed H, Dash P, Dogra P, Carter R, Awad W, Neale G, Thomas PG, Youngblood B. Abstract A26: De novo epigenetic programming restrains PD-1 blockade-mediated T cell rejuvenation Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-A26  0.436
2017 Youngblood B, Hale JS, Kissick HT, Ahn E, Xu X, Wieland A, Araki K, West EE, Ghoneim HE, Fan Y, Dogra P, Davis CW, Konieczny BT, Antia R, Cheng X, et al. Effector CD8 T cells dedifferentiate into long-lived memory cells. Nature. PMID 29236683 DOI: 10.1038/Nature25144  0.423
2017 Ghoneim HE, Fan Y, Moustaki A, Abdelsamed HA, Dash P, Dogra P, Carter R, Awad W, Neale G, Thomas PG, Youngblood B. De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation. Cell. PMID 28648661 DOI: 10.1016/J.Cell.2017.06.007  0.435
2017 Abdelsamed HA, Moustaki A, Fan Y, Dogra P, Ghoneim HE, Zebley CC, Triplett BM, Sekaly RP, Youngblood B. Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis. The Journal of Experimental Medicine. PMID 28490440 DOI: 10.1084/Jem.20161760  0.382
2016 Ghoneim HE, Zamora AE, Thomas PG, Youngblood BA. Cell-Intrinsic Barriers of T Cell-Based Immunotherapy. Trends in Molecular Medicine. PMID 27825667 DOI: 10.1016/J.Molmed.2016.10.002  0.426
2016 Dogra P, Ghoneim HE, Abdelsamed HA, Youngblood B. Generating long-lived CD8(+) T cell memory: insights from epigenetic programs. European Journal of Immunology. PMID 27230488 DOI: 10.1002/Eji.201545550  0.396
2014 Ghoneim HE, McCullers JA. Adjunctive corticosteroid therapy improves lung immunopathology and survival during severe secondary pneumococcal pneumonia in mice. The Journal of Infectious Diseases. 209: 1459-68. PMID 24273183 DOI: 10.1093/Infdis/Jit653  0.586
2013 Ghoneim HE, Thomas PG, McCullers JA. Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections. Journal of Immunology (Baltimore, Md. : 1950). 191: 1250-9. PMID 23804714 DOI: 10.4049/Jimmunol.1300014  0.611
2011 Alymova IV, Green AM, van de Velde N, McAuley JL, Boyd KL, Ghoneim HE, McCullers JA. Immunopathogenic and antibacterial effects of H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82. Journal of Virology. 85: 12324-33. PMID 21937639 DOI: 10.1128/Jvi.05872-11  0.57
2011 Marcelin G, Aldridge JR, Duan S, Ghoneim HE, Rehg J, Marjuki H, Boon AC, McCullers JA, Webby RJ. Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden, in pregnant mice. Journal of Virology. 85: 11208-19. PMID 21865394 DOI: 10.1128/Jvi.00654-11  0.618
2011 Ellebedy AH, Lupfer C, Ghoneim HE, DeBeauchamp J, Kanneganti TD, Webby RJ. Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59. Proceedings of the National Academy of Sciences of the United States of America. 108: 2927-32. PMID 21270336 DOI: 10.1073/Pnas.1012455108  0.384
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