William C. Wetsel, Ph.D. - Publications

Affiliations: 
Neurobiology Duke University, Durham, NC 
Area:
Behavioral neuroscience

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Year Citation  Score
2020 Yu S, Galeffi F, Rodriguiz RM, Wang Z, Shen Y, Lyu J, Li R, Bernstock JD, Johnson KR, Liu S, Sheng H, Turner DA, Wetsel WC, Paschen W, Yang W. Small ubiquitin-like modifier 2 (SUMO2) is critical for memory processes in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32910521 DOI: 10.1096/Fj.202000850Rr  0.323
2020 White AN, Gross JD, Kaski SW, Trexler KR, Wix KA, Wetsel WC, Kinsey SG, Siderovski DP, Setola V. Genetic deletion of in mice affects serotonin transporter expression and function and . Journal of Psychopharmacology (Oxford, England). 269881120944160. PMID 32842837 DOI: 10.1177/0269881120944160  0.387
2019 Shen Y, McCorvy JD, Martini ML, Rodriguiz RM, Pogorelov VM, Ward KM, Wetsel WC, Liu J, Roth BL, Jin J. D2 Dopamine Receptor G protein-biased Partial Agonists Based on Cariprazine. Journal of Medicinal Chemistry. PMID 30964661 DOI: 10.1021/Acs.Jmedchem.9B00508  0.302
2019 McGaughey KD, Yilmaz-Swenson T, Elsayed NM, Cruz DA, Rodriguiz RM, Kritzer MD, Peterchev AV, Roach J, Wetsel WC, Williamson DE. Relative abundance of Akkermansia spp. and other bacterial phylotypes correlates with anxiety- and depressive-like behavior following social defeat in mice. Scientific Reports. 9: 3281. PMID 30824791 DOI: 10.1038/S41598-019-40140-5  0.304
2018 Arbogast T, Razaz P, Ellegood J, McKinstry S, Erdin S, Currall B, Aneichyk T, Lerch JP, Qiu LR, Rodriguiz RM, Mark Henkelman R, Talkowski ME, Wetsel WC, Golzio C, Katsanis N. Kctd13-deficient mice display short-term memory impairment and sex-dependent genetic interactions. Human Molecular Genetics. PMID 30590535 DOI: 10.1093/Hmg/Ddy436  0.359
2018 Helseth AR, Hunanyan AS, Adil S, Linabarger M, Sachdev M, Abdelnour E, Arehart E, Szabo M, Richardson J, Wetsel WC, Hochgeschwender U, Mikati MA. Novel E815K knock-in mouse model of alternating hemiplegia of childhood. Neurobiology of Disease. PMID 30071271 DOI: 10.1016/J.Nbd.2018.07.028  0.359
2018 Bey AL, Wang X, Yan H, Kim N, Passman RL, Yang Y, Cao X, Towers AJ, Hulbert SW, Duffney LJ, Gaidis E, Rodriguiz RM, Wetsel WC, Yin HH, Jiang YH. Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors. Translational Psychiatry. 8: 94. PMID 29700290 DOI: 10.1038/S41398-018-0142-6  0.407
2018 Martyn AC, Toth K, Schmalzigaug R, Hedrick NG, Rodriguiz RM, Yasuda R, Wetsel WC, Premont RT. GIT1 regulates synaptic structural plasticity underlying learning. Plos One. 13: e0194350. PMID 29554125 DOI: 10.1371/Journal.Pone.0194350  0.385
2017 Pappas AL, Bey AL, Wang X, Rossi M, Kim YH, Yan H, Porkka F, Duffney LJ, Phillips SM, Cao X, Ding JD, Rodriguiz RM, Yin HH, Weinberg RJ, Ji RR, ... Wetsel WC, et al. Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers. Jci Insight. 2. PMID 29046483 DOI: 10.1172/Jci.Insight.92052  0.365
2017 Butler RK, Ehling S, Barbar M, Thomas J, Hughes MA, Smith CE, Pogorelov VM, Aryal DK, Wetsel WC, Lascelles BDX. Distinct neuronal populations in the basolateral and central amygdala are activated with acute pain, conditioned fear, and fear-conditioned analgesia. Neuroscience Letters. PMID 28916300 DOI: 10.1016/J.Neulet.2017.09.025  0.332
2017 Berezniuk I, Rodriguiz RM, Zee ML, Marcus DJ, Pintar J, Morgan DJ, Wetsel WC, Fricker LD. ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine. Journal of Neurochemistry. PMID 28881029 DOI: 10.1111/Jnc.14209  0.334
2017 Wang X, Gallegos DA, Pogorelov VM, O'Hare JK, Calakos N, Wetsel WC, West AE. Parvalbumin Interneurons of the Mouse Nucleus Accumbens are Required for Amphetamine-Induced Locomotor Sensitization and Conditioned Place Preference. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28840858 DOI: 10.1038/Npp.2017.178  0.373
2017 Pogorelov VM, Rodriguiz RM, Cheng J, Huang M, Schmerberg CM, Meltzer HY, Roth BL, Kozikowski AP, Wetsel WC. 5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28294132 DOI: 10.1038/Npp.2017.52  0.368
2017 Akkhawattanangkul Y, Maiti P, Xue Y, Aryal D, Wetsel WC, Hamilton D, Fowler SC, McDonald MP. Targeted deletion of GD3 synthase protects against MPTP-induced neurodegeneration. Genes, Brain, and Behavior. PMID 28239983 DOI: 10.1111/Gbb.12377  0.364
2016 Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG. Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911814 DOI: 10.1073/Pnas.1614347113  0.329
2016 Ade KK, Wan Y, Hamann HC, O'Hare JK, Guo W, Quian A, Kumar S, Bhagat S, Rodriguiz RM, Wetsel WC, Conn PJ, Dzirasa K, Huber KM, Calakos N. Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice. Biological Psychiatry. PMID 27436084 DOI: 10.1016/J.Biopsych.2016.04.023  0.334
2016 Bhagat SL, Qiu S, Caffall ZF, Wan Y, Pan Y, Rodriquiz RM, Wetsel WC, Badea A, Hochgeschwender U, Calakos N. Mouse model of rare TOR1A variant found in sporadic focal dystonia impairs domains affected in DYT1 dystonia patients and animal models. Neurobiology of Disease. PMID 27168150 DOI: 10.1016/J.Nbd.2016.05.003  0.314
2016 Wang X, Bey AL, Katz BM, Badea A, Kim N, David LK, Duffney LJ, Kumar S, Mague SD, Hulbert SW, Dutta N, Hayrapetyan V, Yu C, Gaidis E, Zhao S, ... ... Wetsel WC, et al. Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism. Nature Communications. 7: 11459. PMID 27161151 DOI: 10.1038/Ncomms11459  0.342
2016 Barak LS, Bai Y, Peterson S, Evron T, Urs N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, et al. ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse. Acs Chemical Biology. PMID 27119457 DOI: 10.1021/Acschembio.6B00291  0.378
2016 Matak P, Matak A, Moustafa S, Aryal DK, Benner EJ, Wetsel W, Andrews NC. Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929359 DOI: 10.1073/Pnas.1519473113  0.309
2015 Scott JW, Park E, Rodriguiz RM, Oakhill JS, Issa SM, O'Brien MT, Dite TA, Langendorf CG, Wetsel WC, Means AR, Kemp BE. Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder. Scientific Reports. 5: 14436. PMID 26395653 DOI: 10.1038/Srep14436  0.307
2015 Urban DJ, Zhu H, Marcinkiewcz CA, Michaelides M, Oshibuchi H, Rhea D, Aryal DK, Farrell MS, Lowery-Gionta E, Olsen RH, Wetsel WC, Kash TL, Hurd YL, Tecott LH, Roth BL. Elucidation of the Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26383016 DOI: 10.1038/Npp.2015.293  0.315
2015 Park SM, Chen M, Schmerberg CM, Dulman RS, Rodriguiz RM, Caron MG, Jin J, Wetsel WC. Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-like Behavior in Hypoglutamatergic Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26129680 DOI: 10.1038/Npp.2015.196  0.469
2015 Kim IH, Rossi MA, Aryal DK, Racz B, Kim N, Uezu A, Wang F, Wetsel WC, Weinberg RJ, Yin H, Soderling SH. Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine. Nature Neuroscience. 18: 883-91. PMID 25938885 DOI: 10.1038/Nn.4015  0.332
2015 Sachs BD, Rodriguiz RM, Tran HL, Iyer A, Wetsel WC, Caron MG. Serotonin deficiency alters susceptibility to the long-term consequences of adverse early life experience. Psychoneuroendocrinology. 53: 69-81. PMID 25602134 DOI: 10.1016/J.Psyneuen.2014.12.019  0.324
2015 Cheng Y, Rodriguiz RM, Murthy SR, Senatorov V, Thouennon E, Cawley NX, Aryal DK, Ahn S, Lecka-Czernik B, Wetsel WC, Loh YP. Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone. Molecular Psychiatry. 20: 744-54. PMID 25330741 DOI: 10.1038/Mp.2014.136  0.328
2014 Wang L, Rodriguiz RM, Wetsel WC, Sheng H, Zhao S, Liu X, Paschen W, Yang W. Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories. Journal of Psychiatry & Neuroscience : Jpn. 39: 259-66. PMID 24690371 DOI: 10.1503/Jpn.130148  0.334
2014 Deng JV, Wan Y, Wang X, Cohen S, Wetsel WC, Greenberg ME, Kenny PJ, Calakos N, West AE. MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4519-27. PMID 24671997 DOI: 10.1523/Jneurosci.2821-13.2014  0.374
2014 Gaier ED, Rodriguiz RM, Zhou J, Ralle M, Wetsel WC, Eipper BA, Mains RE. In vivo and in vitro analyses of amygdalar function reveal a role for copper. Journal of Neurophysiology. 111: 1927-39. PMID 24554785 DOI: 10.1152/Jn.00631.2013  0.322
2013 Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, ... ... Wetsel WC, et al. Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. Neuron. 80: 429-41. PMID 24139043 DOI: 10.1016/J.Neuron.2013.08.013  0.309
2013 Wetsel WC, Rodriguiz RM, Guillemot J, Rousselet E, Essalmani R, Kim IH, Bryant JC, Marcinkiewicz J, Desjardins R, Day R, Constam DB, Prat A, Seidah NG. Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 17362-7. PMID 24101515 DOI: 10.1073/Pnas.1314698110  0.372
2013 Gomes I, Aryal DK, Wardman JH, Gupta A, Gagnidze K, Rodriguiz RM, Kumar S, Wetsel WC, Pintar JE, Fricker LD, Devi LA. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proceedings of the National Academy of Sciences of the United States of America. 110: 16211-6. PMID 24043826 DOI: 10.1073/Pnas.1312938110  0.344
2013 Gaier ED, Miller MB, Ralle M, Aryal D, Wetsel WC, Mains RE, Eipper BA. Peptidylglycine α-amidating monooxygenase heterozygosity alters brain copper handling with region specificity. Journal of Neurochemistry. 127: 605-19. PMID 24032518 DOI: 10.1111/Jnc.12438  0.324
2013 Sachs BD, Rodriguiz RM, Siesser WB, Kenan A, Royer EL, Jacobsen JP, Wetsel WC, Caron MG. The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2081-94. PMID 23672796 DOI: 10.1017/S1461145713000321  0.309
2013 Kim IH, Racz B, Wang H, Burianek L, Weinberg R, Yasuda R, Wetsel WC, Soderling SH. Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6081-92. PMID 23554489 DOI: 10.1523/Jneurosci.0035-13.2013  0.316
2013 Rodriguiz RM, Wilkins JJ, Creson TK, Biswas R, Berezniuk I, Fricker AD, Fricker LD, Wetsel WC. Emergence of anxiety-like behaviours in depressive-like Cpe(fat/fat) mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1623-34. PMID 23442571 DOI: 10.1017/S1461145713000059  0.344
2012 Wong P, Chang CC, Marx CE, Caron MG, Wetsel WC, Zhang X. Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice. Plos One. 7: e51455. PMID 23240026 DOI: 10.1371/Journal.Pone.0051455  0.354
2012 Por ED, Bierbower SM, Berg KA, Gomez R, Akopian AN, Wetsel WC, Jeske NA. β-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel. The Journal of Biological Chemistry. 287: 37552-63. PMID 22952227 DOI: 10.1074/Jbc.M112.391847  0.324
2012 Chen X, Sassano MF, Zheng L, Setola V, Chen M, Bai X, Frye SV, Wetsel WC, Roth BL, Jin J. Structure-functional selectivity relationship studies of β-arrestin-biased dopamine Dâ‚‚ receptor agonists. Journal of Medicinal Chemistry. 55: 7141-53. PMID 22845053 DOI: 10.1021/Jm300603Y  0.429
2012 Cawley NX, Wetsel WC, Murthy SR, Park JJ, Pacak K, Loh YP. New roles of carboxypeptidase E in endocrine and neural function and cancer. Endocrine Reviews. 33: 216-53. PMID 22402194 DOI: 10.1210/Er.2011-1039  0.314
2012 Lee TH, Szabo ST, Fowler JC, Mannelli P, Mangum OB, Beyer WF, Patkar A, Wetsel WC. Pharmacologically-mediated reactivation and reconsolidation blockade of the psychostimulant-abuse circuit: a novel treatment strategy. Drug and Alcohol Dependence. 124: 11-8. PMID 22356892 DOI: 10.1016/J.Drugalcdep.2012.01.021  0.314
2012 Fukada M, Hanai A, Nakayama A, Suzuki T, Miyata N, Rodriguiz RM, Wetsel WC, Yao TP, Kawaguchi Y. Loss of deacetylation activity of Hdac6 affects emotional behavior in mice. Plos One. 7: e30924. PMID 22328923 DOI: 10.1371/Journal.Pone.0030924  0.342
2012 Hutchinson AN, Deng JV, Aryal DK, Wetsel WC, West AE. Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 321-37. PMID 21956448 DOI: 10.1038/Npp.2011.190  0.332
2011 Daigle TL, Wetsel WC, Caron MG. Opposite function of dopamine D1 and N-methyl-D-aspartate receptors in striatal cannabinoid-mediated signaling. The European Journal of Neuroscience. 34: 1378-89. PMID 22034973 DOI: 10.1111/J.1460-9568.2011.07874.X  0.348
2011 Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/Pnas.1104807108  0.443
2011 Cohen S, Gabel HW, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME. Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron. 72: 72-85. PMID 21982370 DOI: 10.1016/J.Neuron.2011.08.022  0.306
2011 Miller LK, Hou X, Rodriguiz RM, Gagnidze K, Sweedler JV, Wetsel WC, Devi LA. Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord. Journal of Neurochemistry. 119: 1074-85. PMID 21972895 DOI: 10.1111/J.1471-4159.2011.07513.X  0.323
2011 Rodriguiz RM, Colvin JS, Wetsel WC. Neurophenotyping genetically modified mice for social behavior. Methods in Molecular Biology (Clifton, N.J.). 768: 343-63. PMID 21805253 DOI: 10.1007/978-1-61779-204-5_19  0.308
2011 Wang X, McCoy PA, Rodriguiz RM, Pan Y, Je HS, Roberts AC, Kim CJ, Berrios J, Colvin JS, Bousquet-Moore D, Lorenzo I, Wu G, Weinberg RJ, Ehlers MD, Philpot BD, ... ... Wetsel WC, et al. Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. Human Molecular Genetics. 20: 3093-108. PMID 21558424 DOI: 10.1093/Hmg/Ddr212  0.384
2010 Gaier ED, Rodriguiz RM, Ma XM, Sivaramakrishnan S, Bousquet-Moore D, Wetsel WC, Eipper BA, Mains RE. Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13656-69. PMID 20943906 DOI: 10.1523/Jneurosci.2200-10.2010  0.364
2010 Deng JV, Rodriguiz RM, Hutchinson AN, Kim IH, Wetsel WC, West AE. MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants. Nature Neuroscience. 13: 1128-36. PMID 20711186 DOI: 10.1038/Nn.2614  0.384
2010 Kile BM, Guillot TS, Venton BJ, Wetsel WC, Augustine GJ, Wightman RM. Synapsins differentially control dopamine and serotonin release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9762-70. PMID 20660258 DOI: 10.1523/Jneurosci.2071-09.2010  0.321
2010 McDowell KA, Hutchinson AN, Wong-Goodrich SJ, Presby MM, Su D, Rodriguiz RM, Law KC, Williams CL, Wetsel WC, West AE. Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7453-65. PMID 20519520 DOI: 10.1523/Jneurosci.3997-09.2010  0.377
2010 Crooks KR, Kleven DT, Rodriguiz RM, Wetsel WC, McNamara JO. TrkB signaling is required for behavioral sensitization and conditioned place preference induced by a single injection of cocaine. Neuropharmacology. 58: 1067-77. PMID 20176040 DOI: 10.1016/J.Neuropharm.2010.01.014  0.31
2010 Porton B, Rodriguiz RM, Phillips LE, Gilbert JW, Feng J, Greengard P, Kao HT, Wetsel WC. Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear. Genes, Brain, and Behavior. 9: 257-68. PMID 20050925 DOI: 10.1111/J.1601-183X.2009.00555.X  0.398
2010 Bousquet-Moore D, Prohaska JR, Nillni EA, Czyzyk T, Wetsel WC, Mains RE, Eipper BA. Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. Neurobiology of Disease. 37: 130-40. PMID 19815072 DOI: 10.1016/J.Nbd.2009.09.016  0.328
2009 Allen KD, Griffin TM, Rodriguiz RM, Wetsel WC, Kraus VB, Huebner JL, Boyd LM, Setton LA. Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. Arthritis and Rheumatism. 60: 2684-93. PMID 19714629 DOI: 10.1002/Art.24783  0.373
2009 Nehrenberg DL, Rodriguiz RM, Cyr M, Zhang X, Lauder JM, Gariépy JL, Wetsel WC. An anxiety-like phenotype in mice selectively bred for aggression. Behavioural Brain Research. 201: 179-91. PMID 19428632 DOI: 10.1016/J.Bbr.2009.02.010  0.725
2009 Schmalzigaug R, Rodriguiz RM, Bonner PE, Davidson CE, Wetsel WC, Premont RT. Impaired fear response in mice lacking GIT1. Neuroscience Letters. 458: 79-83. PMID 19383529 DOI: 10.1016/J.Neulet.2009.04.037  0.416
2009 Schmalzigaug R, Rodriguiz RM, Phillips LE, Davidson CE, Wetsel WC, Premont RT. Anxiety-like behaviors in mice lacking GIT2. Neuroscience Letters. 451: 156-61. PMID 19114090 DOI: 10.1016/J.Neulet.2008.12.034  0.386
2008 Rodriguiz RM, Gadnidze K, Ragnauth A, Dorr N, Yanagisawa M, Wetsel WC, Devi LA. Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory. Genes, Brain, and Behavior. 7: 418-26. PMID 21450041 DOI: 10.1111/J.1601-183X.2007.00365.X  0.327
2008 Chen Q, Xiong X, Lee TH, Liu Y, Wetsel WC, Zhang X. Neural plasticity and addiction: integrin-linked kinase and cocaine behavioral sensitization. Journal of Neurochemistry. 107: 679-89. PMID 18702665 DOI: 10.1111/J.1471-4159.2008.05619.X  0.302
2008 Taylor GA, Rodriguiz RM, Greene RI, Daniell X, Henry SC, Crooks KR, Kotloski R, Tessarollo L, Phillips LE, Wetsel WC. Behavioral characterization of P311 knockout mice. Genes, Brain, and Behavior. 7: 786-95. PMID 18616608 DOI: 10.1111/J.1601-183X.2008.00420.X  0.365
2008 Chen Q, Xiong X, Lee TH, Liu Y, Sun QA, Wetsel W, Zhang X. Adeno-associated virus-mediated ILK gene silencing in the rat NAc core. Journal of Neuroscience Methods. 173: 208-14. PMID 18602949 DOI: 10.1016/J.Jneumeth.2008.06.004  0.316
2008 Woronowicz A, Koshimizu H, Chang SY, Cawley NX, Hill JM, Rodriguiz RM, Abebe D, Dorfman C, Senatorov V, Zhou A, Xiong ZG, Wetsel WC, Loh YP. Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits. Hippocampus. 18: 1051-63. PMID 18570185 DOI: 10.1002/Hipo.20462  0.357
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Cools MJ, Wetsel WC, Gainetdinov RR, Caron MG. Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proceedings of the National Academy of Sciences of the United States of America. 105: 1333-8. PMID 18212115 DOI: 10.1073/Pnas.0711496105  0.321
2008 Beaulieu JM, Marion S, Rodriguiz RM, Medvedev IO, Sotnikova TD, Ghisi V, Wetsel WC, Lefkowitz RJ, Gainetdinov RR, Caron MG. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell. 132: 125-36. PMID 18191226 DOI: 10.1016/J.Cell.2007.11.041  0.315
2008 Welch J, Lu J, Rodriguiz R, Trotta N, Peca J, Ding J, Feliciano C, Chen M, Adams JP, Luo J, Dudek S, Weinberg R, Calakos N, Wetsel W, Feng G. [SY5.1]: Synaptic and circuitry mechanisms of obsessive compulsive‐like behaviors in mice International Journal of Developmental Neuroscience. 26: 835-835. DOI: 10.1016/J.Ijdevneu.2008.09.033  0.467
2007 Fukui M, Rodriguiz RM, Zhou J, Jiang SX, Phillips LE, Caron MG, Wetsel WC. Vmat2 heterozygous mutant mice display a depressive-like phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10520-9. PMID 17898223 DOI: 10.1523/Jneurosci.4388-06.2007  0.386
2007 Welch JM, Lu J, Rodriguiz RM, Trotta NC, Peca J, Ding JD, Feliciano C, Chen M, Adams JP, Luo J, Dudek SM, Weinberg RJ, Calakos N, Wetsel WC, Feng G. Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. Nature. 448: 894-900. PMID 17713528 DOI: 10.1038/Nature06104  0.493
2007 Chen Q, Lee TH, Wetsel WC, Sun QA, Liu Y, Davidson C, Xiong X, Ellinwood EH, Zhang X. Reversal of cocaine sensitization-induced behavioral sensitization normalizes GAD67 and GABAA receptor alpha2 subunit expression, and PKC zeta activity. Biochemical and Biophysical Research Communications. 356: 733-8. PMID 17382295 DOI: 10.1016/J.Bbrc.2007.03.041  0.33
2007 Badea A, Nicholls PJ, Johnson GA, Wetsel WC. Neuroanatomical phenotypes in the reeler mouse. Neuroimage. 34: 1363-74. PMID 17185001 DOI: 10.1016/J.Neuroimage.2006.09.053  0.364
2007 Zhang X, Lee TH, Davidson C, Lazarus C, Wetsel WC, Ellinwood EH. Reversal of cocaine-induced behavioral sensitization and associated phosphorylation of the NR2B and GluR1 subunits of the NMDA and AMPA receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 377-87. PMID 16794574 DOI: 10.1038/Sj.Npp.1301101  0.31
2007 Allen K, Griffin T, Wetsel W, Rodriguiz R, Boyd L, Setton L. 3 TYPE IX COLLAGEN KNOCKOUT IS ASSOCIATED WITH ALTERED GAIT BEHAVIORS AND MECHANICAL ALLODYNIA IN MICE Osteoarthritis and Cartilage. 15: C16. DOI: 10.1016/S1063-4584(07)61639-2  0.345
2006 Zhang X, Lee TH, Xiong X, Chen Q, Davidson C, Wetsel WC, Ellinwood EH. Methamphetamine induces long-term changes in GABAA receptor alpha2 subunit and GAD67 expression. Biochemical and Biophysical Research Communications. 351: 300-5. PMID 17056007 DOI: 10.1016/J.Bbrc.2006.10.046  0.304
2006 Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, ... ... Wetsel WC, et al. Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron. 51: 601-12. PMID 16950158 DOI: 10.1016/J.Neuron.2006.08.005  0.396
2006 Nehrenberg D, Peterson R, Styner M, Kim H, Wetsel W, Lauder J. [P113]: High anxiety/aggressive mice exhibit serotonergic developmental deficits that persist into adulthood International Journal of Developmental Neuroscience. 24: 544-544. DOI: 10.1016/J.Ijdevneu.2006.09.175  0.709
2005 Sotnikova TD, Beaulieu JM, Barak LS, Wetsel WC, Caron MG, Gainetdinov RR. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. Plos Biology. 3: e271. PMID 16050778 DOI: 10.1371/Journal.Pbio.0030271  0.308
2005 Gammon CM, Freeman GM, Xie W, Xie W, Petersen SL, Wetsel WC. Regulation of gonadotropin-releasing hormone secretion by cannabinoids. Endocrinology. 146: 4491-9. PMID 16020480 DOI: 10.1210/En.2004-1672  0.32
2005 Pillai-Nair N, Panicker AK, Rodriguiz RM, Gilmore KL, Demyanenko GP, Huang JZ, Wetsel WC, Maness PF. Neural cell adhesion molecule-secreting transgenic mice display abnormalities in GABAergic interneurons and alterations in behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4659-71. PMID 15872114 DOI: 10.1523/Jneurosci.0565-05.2005  0.415
2005 Jacobsen JP, Rodriguiz RM, Mørk A, Wetsel WC. Monoaminergic dysregulation in glutathione-deficient mice: possible relevance to schizophrenia? Neuroscience. 132: 1055-72. PMID 15857710 DOI: 10.1016/J.Neuroscience.2005.01.059  0.384
2005 Pogorelov VM, Rodriguiz RM, Insco ML, Caron MG, Wetsel WC. Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1818-31. PMID 15856082 DOI: 10.1038/Sj.Npp.1300724  0.416
2004 Grove M, Demyanenko G, Echarri A, Zipfel PA, Quiroz ME, Rodriguiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, Pendergast AM. ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Molecular and Cellular Biology. 24: 10905-22. PMID 15572692 DOI: 10.1128/Mcb.24.24.10905-10922.2004  0.312
2004 Cawley NX, Zhou J, Hill JM, Abebe D, Romboz S, Yanik T, Rodriguiz RM, Wetsel WC, Loh YP. The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. Endocrinology. 145: 5807-19. PMID 15358678 DOI: 10.1210/En.2004-0847  0.372
2004 Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG. Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2. Molecular and Cellular Biology. 24: 4166-73. PMID 15121838 DOI: 10.1128/Mcb.24.10.4166-4173.2004  0.317
2004 Srinivasan S, Bunch DO, Feng Y, Rodriguiz RM, Li M, Ravenell RL, Luo GX, Arimura A, Fricker LD, Eddy EM, Wetsel WC. Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice. Endocrinology. 145: 2023-34. PMID 14715715 DOI: 10.1210/En.2003-1442  0.327
2004 Rodriguiz RM, Chu R, Caron MG, Wetsel WC. Aberrant responses in social interaction of dopamine transporter knockout mice. Behavioural Brain Research. 148: 185-98. PMID 14684259 DOI: 10.1016/S0166-4328(03)00187-6  0.364
2003 Trinh JV, Nehrenberg DL, Jacobsen JP, Caron MG, Wetsel WC. Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice. Neuroscience. 118: 297-310. PMID 12699766 DOI: 10.1016/S0306-4522(03)00165-9  0.717
2002 Nillni EA, Xie W, Mulcahy L, Sanchez VC, Wetsel WC. Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice. The Journal of Biological Chemistry. 277: 48587-95. PMID 12270926 DOI: 10.1074/Jbc.M206702200  0.339
2002 Haller J, Bakos N, Rodriguiz RM, Caron MG, Wetsel WC, Liposits Z. Behavioral responses to social stress in noradrenaline transporter knockout mice: effects on social behavior and depression. Brain Research Bulletin. 58: 279-84. PMID 12128153 DOI: 10.1016/S0361-9230(02)00789-X  0.325
2000 Ribar TJ, Rodriguiz RM, Khiroug L, Wetsel WC, Augustine GJ, Means AR. Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC107. PMID 11069976 DOI: 10.1523/Jneurosci.20-22-J0004.2000  0.38
2000 Xu F, Gainetdinov RR, Wetsel WC, Jones SR, Bohn LM, Miller GW, Wang YM, Caron MG. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nature Neuroscience. 3: 465-71. PMID 10769386 DOI: 10.1038/74839  0.393
1999 Davis BJ, Lennard DE, Lee CA, Tiano HF, Morham SG, Wetsel WC, Langenbach R. Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta. Endocrinology. 140: 2685-95. PMID 10342859 DOI: 10.1210/Endo.140.6.6715  0.367
1999 Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science (New York, N.Y.). 283: 397-401. PMID 9888856 DOI: 10.1126/Science.283.5400.397  0.358
1998 Migliaccio S, Washburn TF, Fillo S, Rivera H, Teti A, Korach KS, Wetsel WC. Modulation of estrogen receptor levels in mouse uterus by protein kinase C isoenzymes. Endocrinology. 139: 4598-606. PMID 9794471 DOI: 10.1210/Endo.139.11.6300  0.3
1998 Lindzey J, Wetsel WC, Couse JF, Stoker T, Cooper R, Korach KS. Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knockout mice. Endocrinology. 139: 4092-101. PMID 9751487 DOI: 10.1210/Endo.139.10.6253  0.304
1998 Migliaccio S, Bernardini S, Wetsel WC, Korach KS, Faraggiana T, Teti A. Protein kinase C modulates estrogen receptors in differentiated osteoblastic cells in vitro. Steroids. 63: 352-4. PMID 9618801 DOI: 10.1016/S0039-128X(98)00040-3  0.313
1997 Caron KM, Soo SC, Wetsel WC, Stocco DM, Clark BJ, Parker KL. Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. 94: 11540-5. PMID 9326645 DOI: 10.1073/Pnas.94.21.11540  0.344
1997 Bossé R, Fumagalli F, Jaber M, Giros B, Gainetdinov RR, Wetsel WC, Missale C, Caron MG. Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. 19: 127-38. PMID 9247269 DOI: 10.1016/S0896-6273(00)80353-0  0.344
1996 Pascale A, Fortino I, Govoni S, Trabucchi M, Wetsel WC, Battaini F. Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex. Journal of Neurochemistry. 67: 2471-7. PMID 8931480 DOI: 10.1046/J.1471-4159.1996.67062471.X  0.312
1996 Wetsel WC, Hill DF, Ojeda SR. Basic fibroblast growth factor regulates the conversion of pro-luteinizing hormone-releasing hormone (Pro-LHRH) to LHRH in immortalized hypothalamic neurons. Endocrinology. 137: 2606-16. PMID 8641215 DOI: 10.1210/Endo.137.6.8641215  0.302
1996 Voigt P, Ma YJ, Gonzalez D, Fahrenbach WH, Wetsel WC, Berg-von der Emde K, Hill DF, Taylor KG, Costa ME, Seidah NG, Ojeda SR. Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons. Endocrinology. 137: 2593-605. PMID 8641214 DOI: 10.1210/Endo.137.6.8641214  0.322
1993 Favit A, Wetsel WC, Negro-Vilar A. Differential expression of gamma-aminobutyric acid receptors in immortalized luteinizing hormone-releasing hormone neurons. Endocrinology. 133: 1983-9. PMID 8404645 DOI: 10.1210/Endo.133.5.8404645  0.309
1987 Wetsel WC, Fernstrom JD. In vivo biosynthesis of arginine vasopressin and oxytocin in hypothalami from intact and hypophysectomized rats. Endocrinology. 120: 2562-8. PMID 2883002 DOI: 10.1210/Endo-120-6-2562  0.514
1986 Wetsel WC, Fernstrom JD. Effect of hypophysectomy on somatostatin-14 and somatostatin-28 biosynthesis in the rat hypothalamus. Brain Research. 370: 315-20. PMID 2871892 DOI: 10.1016/0006-8993(86)90486-5  0.522
1984 Wetsel W, Grubb P, Fernstrom J. Regional changes in somatostatin(SRIF)-14 and SRIF-28 levels in the central nervous system (CNS) of the developing rat Journal of Steroid Biochemistry. 20: 1621. DOI: 10.1016/0022-4731(84)90925-7  0.447
1976 Wetsel WC, Riccio DC, Hinderliter CF. Effects of artificial rewarming upon hypothermia-induced retrograde amnesia Physiological Psychology. 4: 201-206. DOI: 10.3758/Bf03326580  0.505
Low-probability matches (unlikely to be authored by this person)
1996 Belsham DD, Wetsel WC, Mellon PL. NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression. The Embo Journal. 15: 538-47. PMID 8599937 DOI: 10.1002/J.1460-2075.1996.Tb00386.X  0.3
2019 Kritzer M, Lai C, Tharayil J, Rosario W, Botros P, Lowell A, Cruz D, Rodriguez R, Wetsel W, Peterchev A, Williamson D. T114. Behavioral Changes and Glial Staining in Mice Subjected to the Chronic Social Defeat Stress Followed by Electroconvulsive Stimulation Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.437  0.3
2019 Martini ML, Ray C, Yu X, Liu J, Pogorelov V, Wetsel WC, Huang XP, McCorvy J, Caron MG, Jin J. Designing Functionally Selective Non-Catechol Dopamine D1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity. Acs Chemical Neuroscience. PMID 31387346 DOI: 10.1021/Acschemneuro.9B00410  0.299
1993 Migliaccio S, Wetsel WC, Fox WM, Washburn TF, Korach KS. Endogenous protein kinase-C activation in osteoblast-like cells modulates responsiveness to estrogen and estrogen receptor levels. Molecular Endocrinology (Baltimore, Md.). 7: 1133-43. PMID 8247015 DOI: 10.1210/Mend.7.9.8247015  0.298
2009 Liu Y, Sun QA, Chen Q, Lee TH, Huang Y, Wetsel WC, Michelotti GA, Sullenger BA, Zhang X. Targeting inhibition of GluR1 Ser845 phosphorylation with an RNA aptamer that blocks AMPA receptor trafficking. Journal of Neurochemistry. 108: 147-57. PMID 19046328 DOI: 10.1111/J.1471-4159.2008.05748.X  0.298
2015 Klein RC, Acheson SK, Qadri LH, Dawson AA, Rodriguiz RM, Wetsel WC, Moore SD, Laskowitz DT, Dawson HN. Opposing effects of traumatic brain injury on excitatory synaptic function in the lateral amygdala in the absence and presence of preinjury stress. Journal of Neuroscience Research. PMID 26707710 DOI: 10.1002/Jnr.23702  0.296
2010 Chen Q, Zhu X, Zhang Y, Wetsel WC, Lee TH, Zhang X. Integrin-linked kinase is involved in cocaine sensitization by regulating PSD-95 and synapsin I expression and GluR1 Ser845 phosphorylation. Journal of Molecular Neuroscience : Mn. 40: 284-94. PMID 19629758 DOI: 10.1007/S12031-009-9218-3  0.296
2016 Nagy E, Rodriguiz RM, Wetsel WC, MacIver NJ, Hale LP. Reproduction and Growth in a Murine Model of Early Life-Onset Inflammatory Bowel Disease. Plos One. 11: e0152764. PMID 27045690 DOI: 10.1371/Journal.Pone.0152764  0.295
1995 Wetsel WC, Liposits Z, Seidah NG, Collins S. Expression of candidate pro-GnRH processing enzymes in rat hypothalamus and an immortalized hypothalamic neuronal cell line. Neuroendocrinology. 62: 166-77. PMID 8584116 DOI: 10.1159/000127001  0.295
2004 Longo M, Brama M, Marino M, Bernardini S, Korach KS, Wetsel WC, Scandurra R, Faraggiana T, Spera G, Baron R, Teti A, Migliaccio S. Interaction of estrogen receptor alpha with protein kinase C alpha and c-Src in osteoblasts during differentiation. Bone. 34: 100-11. PMID 14751567 DOI: 10.1016/J.Bone.2003.09.007  0.295
2004 Gitler D, Takagishi Y, Feng J, Ren Y, Rodriguiz RM, Wetsel WC, Greengard P, Augustine GJ. Different presynaptic roles of synapsins at excitatory and inhibitory synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11368-80. PMID 15601943 DOI: 10.1523/Jneurosci.3795-04.2004  0.294
1993 Wetsel WC, Eraly SA, Whyte DB, Mellon PL. Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons. Endocrinology. 132: 2360-70. PMID 8504741 DOI: 10.1210/Endo.132.6.8504741  0.294
2020 Slosky LM, Bai Y, Toth K, Ray C, Rochelle LK, Badea A, Chandrasekhar R, Pogorelov VM, Abraham DM, Atluri N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney P, Yuan H, ... ... Wetsel WC, et al. β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. Cell. PMID 32470395 DOI: 10.1016/J.Cell.2020.04.053  0.292
1991 Liposits Z, Merchenthaler I, Wetsel WC, Reid JJ, Mellon PL, Weiner RI, Negro-Vilar A. Morphological characterization of immortalized hypothalamic neurons synthesizing luteinizing hormone-releasing hormone. Endocrinology. 129: 1575-83. PMID 1874189 DOI: 10.1210/Endo-129-3-1575  0.291
1988 Wetsel WC, Culler MD, Johnston CA, Negro-Vilar A. Processing of the luteinizing hormone-releasing hormone precursor in the preoptic area and hypothalamus of the rat. Molecular Endocrinology (Baltimore, Md.). 2: 22-31. PMID 3041260 DOI: 10.1210/Mend-2-1-22  0.291
2015 Cheng J, Giguère PM, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Huang XP, Zhu H, McCorvy JD, Wetsel WC, Roth BL, Kozikowski AP. Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. Journal of Medicinal Chemistry. PMID 26704965 DOI: 10.1021/Acs.Jmedchem.5B01153  0.291
2019 Velagapudi R, Subramaniyan S, Xiong C, Porkka F, Rodriguiz RM, Wetsel WC, Terrando N. Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model. Frontiers in Immunology. 10: 2675. PMID 31911786 DOI: 10.3389/Fimmu.2019.02675  0.291
2006 Venton BJ, Seipel AT, Phillips PE, Wetsel WC, Gitler D, Greengard P, Augustine GJ, Wightman RM. Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3206-9. PMID 16554471 DOI: 10.1523/Jneurosci.4901-04.2006  0.29
2008 Ream MA, Chandra R, Peavey M, Ray AM, Roffler-Tarlov S, Kim HG, Wetsel WC, Rockman HA, Chikaraishi DM. High oxygen prevents fetal lethality due to lack of catecholamines. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R942-53. PMID 18635452 DOI: 10.1152/Ajpregu.00860.2007  0.289
2019 Kritzer M, Rosario W, Tharayil J, Lai C, Botros P, Lowell A, Cruz D, Rodriguiz R, Wetsel W, Peterchev A, Williamson D. Electroconvulsive Stimulation Increases Astrocytes In Mice Subjected To Chronic Social Defeat Stress Brain Stimulation. 12: 543. DOI: 10.1016/J.Brs.2018.12.791  0.289
1991 Wetsel WC, Mellon PL, Weiner RI, Negro-Vilar A. Metabolism of pro-luteinizing hormone-releasing hormone in immortalized hypothalamic neurons. Endocrinology. 129: 1584-95. PMID 1714837 DOI: 10.1210/Endo-129-3-1584  0.287
2019 Pogorelov VM, Kao HT, Augustine GJ, Wetsel WC. Postsynaptic Mechanisms Render Syn I/II/III Mice Highly Responsive to Psychostimulants. The International Journal of Neuropsychopharmacology. PMID 31188434 DOI: 10.1093/Ijnp/Pyz019  0.286
2000 Jeohn GH, Chang RC, Kim WG, Wilson B, Mohney RP, Wetsel WC, Hong JS. Post-transcriptional inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by Gö6976 in murine microglia. Brain Research. Molecular Brain Research. 79: 18-31. PMID 10925140 DOI: 10.1016/S0169-328X(00)00081-4  0.285
1992 Wetsel WC, Valença MM, Merchenthaler I, Liposits Z, López FJ, Weiner RI, Mellon PL, Negro-Vilar A. Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons. Proceedings of the National Academy of Sciences of the United States of America. 89: 4149-53. PMID 1570341 DOI: 10.1073/Pnas.89.9.4149  0.285
1993 Merchenthaler I, Liposits Z, Reid JJ, Wetsel WC. Light and electron microscopic immunocytochemical localization of PKC delta immunoreactivity in the rat central nervous system. The Journal of Comparative Neurology. 336: 378-99. PMID 8263228 DOI: 10.1002/Cne.903360306  0.285
2015 Hunanyan AS, Fainberg NA, Linabarger M, Arehart E, Leonard AS, Adil SM, Helseth AR, Swearingen AK, Forbes SL, Rodriguiz RM, Rhodes T, Yao X, Kibbi N, Hochman DW, Wetsel WC, et al. Knock-in mouse model of alternating hemiplegia of childhood: behavioral and electrophysiologic characterization. Epilepsia. 56: 82-93. PMID 25523819 DOI: 10.1111/Epi.12878  0.284
2011 Bhatia KS, Szabo ST, Fowler JC, Wetsel WC, Lee TH. Reversal of long-term methamphetamine sensitization by combination of pergolide with ondansetron or ketanserin, but not mirtazapine. Behavioural Brain Research. 223: 227-32. PMID 21571009 DOI: 10.1016/J.Bbr.2011.04.045  0.283
2011 Carlson BR, Lloyd KE, Kruszewski A, Kim IH, Rodriguiz RM, Heindel C, Faytell M, Dudek SM, Wetsel WC, Soderling SH. WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2447-60. PMID 21325512 DOI: 10.1523/Jneurosci.4433-10.2011  0.283
2016 Wetsel W, Caron MG, Jin J, Park SM, Pogorelov VM, Rodriguiz RM, Schmerberg CM. PM435. Targeting Functional Selectivity of the Dopamine D2 Receptor for Treatment of Schizophrenia-like Behaviors The International Journal of Neuropsychopharmacology. 19: 58-58. DOI: 10.1093/Ijnp/Pyw041.435  0.282
2019 Badea A, Delpratt NA, Anderson RJ, Dibb R, Qi Y, Wei H, Liu C, Wetsel WC, Avants BB, Colton C. Multivariate MR biomarkers better predict cognitive dysfunction in mouse models of Alzheimer's disease. Magnetic Resonance Imaging. PMID 30940494 DOI: 10.1016/J.Mri.2019.03.022  0.282
2001 Kreda SM, Sumner M, Fillo S, Ribeiro CM, Luo GX, Xie W, Daniel KW, Shears S, Collins S, Wetsel WC. alpha(1)-adrenergic receptors mediate LH-releasing hormone secretion through phospholipases C and A(2) in immortalized hypothalamic neurons. Endocrinology. 142: 4839-51. PMID 11606452 DOI: 10.1210/Endo.142.11.8506  0.282
2010 Griffin TM, Fermor B, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, Cao L, Setton LA, Guilak F. Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. Arthritis Research & Therapy. 12: R130. PMID 20604941 DOI: 10.1186/Ar3068  0.281
2011 Porton B, Wetsel WC, Kao HT. Synapsin III: role in neuronal plasticity and disease. Seminars in Cell & Developmental Biology. 22: 416-24. PMID 21827867 DOI: 10.1016/J.Semcdb.2011.07.007  0.281
2015 Weitzel DH, Tovmasyan A, Ashcraft KA, Rajic Z, Weitner T, Liu C, Li W, Buckley AF, Prasad MR, Young KH, Rodriguiz RM, Wetsel WC, Peters KB, Spasojevic I, Herndon JE, et al. Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+. Molecular Cancer Therapeutics. 14: 70-9. PMID 25319393 DOI: 10.1158/1535-7163.Mct-14-0343  0.28
2011 Wetsel WC. Hyperthermic effects on behavior. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 27: 353-73. PMID 21591899 DOI: 10.3109/02656736.2010.550905  0.28
2020 Rocereta J, Free RB, Garcia AD, Southall N, Shi L, Lane R, Wetsel W, Marugan JJ, Sibley DR. Optimization of a novel D 2 dopamine receptor antagonist with unprecedented selectivity as a therapeutic to treat psychosis and other neuropsychiatric disorders The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04066  0.28
1994 Battaini F, Garbillo G, Bergamaschi S, Parenti M, Wetsel WC, Govoni S, Trabucchi M. Regulation of protein kinase C in NG108-15 cell differentiation. Biochemical and Biophysical Research Communications. 201: 135-42. PMID 8198566 DOI: 10.1006/Bbrc.1994.1679  0.279
2006 Zhang X, Mi J, Wetsel WC, Davidson C, Xiong X, Chen Q, Ellinwood EH, Lee TH. PI3 kinase is involved in cocaine behavioral sensitization and its reversal with brain area specificity. Biochemical and Biophysical Research Communications. 340: 1144-50. PMID 16414349 DOI: 10.1016/J.Bbrc.2005.12.114  0.279
1989 Wetsel WC, Negro-Vilar A. Testosterone selectively influences protein kinase-C-coupled secretion of proluteinizing hormone-releasing hormone-derived peptides. Endocrinology. 125: 538-47. PMID 2661212 DOI: 10.1210/Endo-125-1-538  0.279
1995 Wetsel WC. Immortalized hypothalamic luteinizing hormone-releasing hormone (LHRH) neurons: a new tool for dissecting the molecular and cellular basis of LHRH physiology. Cellular and Molecular Neurobiology. 15: 43-78. PMID 7648609 DOI: 10.1007/Bf02069558  0.279
2000 Jeohn GH, Wilson B, Wetsel WC, Hong JS. The indolocarbazole Gö6976 protects neurons from lipopolysaccharide/interferon-gamma-induced cytotoxicity in murine neuron/glia co-cultures. Brain Research. Molecular Brain Research. 79: 32-44. PMID 10925141 DOI: 10.1016/S0169-328X(00)00082-6  0.278
1995 Battaini F, Elkabes S, Bergamaschi S, Ladisa V, Lucchi L, De Graan PN, Schuurman T, Wetsel WC, Trabucchi M, Govoni S. Protein kinase C activity, translocation, and conventional isoforms in aging rat brain. Neurobiology of Aging. 16: 137-48. PMID 7777132 DOI: 10.1016/0197-4580(94)00154-5  0.277
2013 Liu G, Gu B, He XP, Joshi RB, Wackerle HD, Rodriguiz RM, Wetsel WC, McNamara JO. Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy. Neuron. 79: 31-8. PMID 23790754 DOI: 10.1016/J.Neuron.2013.04.027  0.276
1996 Zappelli F, Willems D, Osada S, Ohno S, Wetsel WC, Molinaro M, Cossu G, Bouché M. The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis. Developmental Biology. 180: 156-64. PMID 8948582 DOI: 10.1006/Dbio.1996.0292  0.275
2023 Pogorelov VM, Rodriguiz RM, Roth BL, Wetsel WC. The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice. Frontiers in Molecular Biosciences. 10: 1233743. PMID 37900918 DOI: 10.3389/fmolb.2023.1233743  0.274
2009 Roberts AC, Díez-García J, Rodriguiz RM, López IP, Luján R, Martínez-Turrillas R, Picó E, Henson MA, Bernardo DR, Jarrett TM, Clendeninn DJ, López-Mascaraque L, Feng G, Lo DC, Wesseling JF, ... Wetsel WC, et al. Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. Neuron. 63: 342-56. PMID 19679074 DOI: 10.1016/J.Neuron.2009.06.016  0.272
2022 Jaaro-Peled H, Kumar S, Hughes D, Sumitomo A, Kim SH, Zoubovsky S, Hirota-Tsuyada Y, Zala D, Bruyere J, Katz BM, Huang B, Flores R, Narayan S, Hou Z, Economides AN, ... ... Wetsel WC, et al. Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit. Molecular Psychiatry. PMID 35165396 DOI: 10.1038/s41380-021-01389-3  0.272
1997 Colombo PJ, Wetsel WC, Gallagher M. Spatial memory is related to hippocampal subcellular concentrations of calcium-dependent protein kinase C isoforms in young and aged rats. Proceedings of the National Academy of Sciences of the United States of America. 94: 14195-9. PMID 9391176 DOI: 10.1073/Pnas.94.25.14195  0.272
2015 Cheng J, Giguère PM, Onajole OK, Lv W, Gaisin A, Gunosewoyo H, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Vistoli G, Wetsel WC, Roth BL, Kozikowski AP. Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents. Journal of Medicinal Chemistry. 58: 1992-2002. PMID 25633969 DOI: 10.1021/Jm5019274  0.271
1994 Battaini F, Pascale A, Lucchi L, Racchi M, Bergamaschi S, Parenti M, Wetsel WC, Govoni S, Trabucchi M. Expression and regulation of calcium-independent protein kinase C in NG 108-15 cell differentiation. Biochemical and Biophysical Research Communications. 203: 1423-31. PMID 7945290 DOI: 10.1006/Bbrc.1994.2344  0.271
2018 Huffman WJ, Subramaniyan S, Rodriguiz RM, Wetsel WC, Grill WM, Terrando N. Modulation of neuroinflammation and memory dysfunction using percutaneous vagus nerve stimulation in mice. Brain Stimulation. PMID 30337243 DOI: 10.1016/J.Brs.2018.10.005  0.27
1988 Valenca MM, Wetsel WC, Culler MD, Negro-Vilar A. Differential secretion of proLHRH fragments in response to [K+], prostaglandin E2 and C kinase activation. Molecular and Cellular Endocrinology. 55: 95-100. PMID 3282935 DOI: 10.1016/0303-7207(88)90095-0  0.27
1990 Cubeddu LX, Lindley CM, Wetsel W, Carl PL, Negro-Vilar A. Role of angiotensin II and vasopressin in cisplatin-induced emesis. Life Sciences. 46: 699-705. PMID 2314191 DOI: 10.1016/0024-3205(90)90075-3  0.269
2013 Wu C, Jain D, Little D, Anderson J, Huebner J, Kraus V, Rodriguiz R, Wetsel W, Guilak F. Dietary fatty acids differentially affect the development of injury-induced osteoarthritis with diet-induced obesity in mice Osteoarthritis and Cartilage. 21: S224-S225. DOI: 10.1016/J.Joca.2013.02.464  0.269
1995 Bergamaschi S, Binetti G, Govoni S, Wetsel WC, Battaini F, Trabucchi M, Bianchetti A, Racchi M. Defective phorbol ester-stimulated secretion of beta-amyloid precursor protein from Alzheimer's disease fibroblasts. Neuroscience Letters. 201: 1-5. PMID 8830300 DOI: 10.1016/0304-3940(95)12168-4  0.268
2022 Fricker LD, Lemos Duarte M, Jeltyi A, Lueptow L, Fakira AK, Tashima AK, Hochgeschwender U, Wetsel WC, Devi LA. Mice heterozygous for a null mutation of CPE show reduced expression of carboxypeptidase e mRNA and enzyme activity but normal physiology, behavior, and levels of neuropeptides. Brain Research. 1789: 147951. PMID 35618016 DOI: 10.1016/j.brainres.2022.147951  0.266
2009 Yan F, Bikbulatov RV, Mocanu V, Dicheva N, Parker CE, Wetsel WC, Mosier PD, Westkaemper RB, Allen JA, Zjawiony JK, Roth BL. Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor. Biochemistry. 48: 6898-908. PMID 19555087 DOI: 10.1021/Bi900605N  0.265
2019 Yang R, Walder-Christensen KK, Kim N, Wu D, Lorenzo DN, Badea A, Jiang YH, Yin HH, Wetsel WC, Bennett V. autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31285321 DOI: 10.1073/Pnas.1904348116  0.263
1996 Pascale A, Fortino I, Govoni S, Trabucchi M, Wetsel WC, Battaini F. Differential isoform-specific regulation of calcium-independent protein kinase C in rat cerebral cortex. Neuroscience Letters. 214: 99-102. PMID 8878093 DOI: 10.1016/0304-3940(96)12901-3  0.262
2016 Weitzel DH, Tovmasyan A, Ashcraft KA, Boico A, Birer SR, Roy Choudhury K, Herndon J, Rodriguiz RM, Wetsel WC, Peters KB, Spasojevic I, Batinic-Haberle I, Dewhirst MW. Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier. Environmental and Molecular Mutagenesis. PMID 27224425 DOI: 10.1002/Em.22021  0.262
2017 Cho KI, Yoon D, Qiu S, Danziger Z, Grill WM, Wetsel WC, Ferreira PA. Loss of Ranbp2 in motor neurons causes the disruption of nucleocytoplasmic and chemokine signaling and proteostasis of hnRNPH3 and Mmp28, and the development of amyotrophic lateral sclerosis (ALS)-like syndromes. Disease Models & Mechanisms. PMID 28100513 DOI: 10.1242/Dmm.027730  0.261
1989 Wetsel W, Negro-Vilar A. Combined antibody-high-performance liquid chromatography approach to assess prohormone processing. Methods in Enzymology. 168: 517-45. PMID 2657339 DOI: 10.1016/0076-6879(89)68040-8  0.258
2023 Pogorelov VM, Rodriguiz RM, Roth BL, Wetsel WC. The G protein biased serotonin 5-HT 2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice. Biorxiv : the Preprint Server For Biology. PMID 37333376 DOI: 10.1101/2023.06.01.543310  0.258
2021 Rodriguiz RM, Nadkarni V, Means CR, Pogorelov VM, Chiu YT, Roth BL, Wetsel WC. LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1. Scientific Reports. 11: 17690. PMID 34480046 DOI: 10.1038/s41598-021-96736-3  0.258
1992 Wetsel WC, Khan WA, Merchenthaler I, Rivera H, Halpern AE, Phung HM, Negro-Vilar A, Hannun YA. Tissue and cellular distribution of the extended family of protein kinase C isoenzymes. The Journal of Cell Biology. 117: 121-33. PMID 1556149 DOI: 10.1083/Jcb.117.1.121  0.256
2023 Chiu YT, Deutch AY, Wang W, Schmitz GP, Huang KL, Kocak DD, Llorach P, Bowyer K, Liu B, Sciaky N, Hua K, Chen C, Mott SE, Niehaus J, DiBerto JF, ... ... Wetsel WC, et al. A suite of engineered mice for interrogating psychedelic drug actions. Biorxiv : the Preprint Server For Biology. PMID 37808655 DOI: 10.1101/2023.09.25.559347  0.255
2008 Jensen NH, Rodriguiz RM, Caron MG, Wetsel WC, Rothman RB, Roth BL. N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2303-12. PMID 18059438 DOI: 10.1038/Sj.Npp.1301646  0.255
1994 Racchi M, Bergamaschi S, Govoni S, Wetsel WC, Bianchetti A, Binetti G, Battaini F, Trabucchi M. Characterization and distribution of protein kinase C isoforms in human skin fibroblasts. Archives of Biochemistry and Biophysics. 314: 107-11. PMID 7944381 DOI: 10.1006/Abbi.1994.1417  0.254
2019 Kritzer M, Rosario W, Tharayil J, Lai C, Botros P, Lowell A, Cruz D, Rodriguiz R, Wetsel W, Peterchev A, Williamson D. Erratum to ‘Electroconvulsive stimulation increases astrocyte marker GFAP in mouse hippocampus regardless of chronic social defeat stress’ [12 (2) (March–April 2019) 543] Brain Stimulation. 12. DOI: 10.1016/J.Brs.2019.06.008  0.253
2002 Wetsel WC, Srinivasan S. Pro-GnRH processing. Progress in Brain Research. 141: 221-41. PMID 12512470 DOI: 10.1016/S0079-6123(02)41096-5  0.252
1999 Isaac RE, Michaud A, Keen JN, Williams TA, Coates D, Wetsel WC, Corvol P. Hydrolysis by somatic angiotensin-I converting enzyme of basic dipeptides from a cholecystokinin/gastrin and a LH-RH peptide extended at the C-terminus with gly-Arg/Lys-arg, but not from diarginyl insulin. European Journal of Biochemistry / Febs. 262: 569-74. PMID 10336644 DOI: 10.1046/J.1432-1327.1999.00419.X  0.252
2016 Bao X, Chandramohan V, Reynolds RP, Norton JN, Wetsel WC, Rodriguiz RM, Aryal DK, McLendon RE, Levin ED, Petry NA, Zalutsky MR, Burnett BK, Kuan CT, Pastan IH, Bigner DD. Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats. Investigational New Drugs. PMID 26728879 DOI: 10.1007/S10637-015-0318-3  0.25
2019 Miller-Rhodes P, Kong C, Baht GS, Saminathan P, Rodriguiz RM, Wetsel WC, Gelbard HA, Terrando N. The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders. Journal of Neuroinflammation. 16: 193. PMID 31660984 DOI: 10.1186/S12974-019-1582-5  0.25
1987 Culler MC, Wetsel WC, Valenca MM, Johnston CA, Masotto C, Sar M, Negro-Vilar A. Orchidectomy induces temporal and regional changes in the synthesis and processing of the LHRH prohormone in the rat brain. Advances in Experimental Medicine and Biology. 219: 623-8. PMID 3324686 DOI: 10.1007/978-1-4684-5395-9_32  0.248
1992 Alessenko A, Khan WA, Wetsel WC, Hannun YA. Selective changes in protein kinase C isoenzymes in rat liver nuclei during liver regeneration. Biochemical and Biophysical Research Communications. 182: 1333-9. PMID 1540177 DOI: 10.1016/0006-291X(92)91879-U  0.246
2007 Porton B, Wetsel WC. Reduction of synapsin III in the prefrontal cortex of individuals with schizophrenia. Schizophrenia Research. 94: 366-70. PMID 17540541 DOI: 10.1016/J.Schres.2007.04.016  0.245
2016 Badea A, Kane L, Anderson RJ, Qi Y, Foster M, Cofer GP, Medvitz N, Buckley AF, Badea AK, Wetsel WC, Colton CA. The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer's disease. Neuroimage. PMID 27521741 DOI: 10.1016/J.Neuroimage.2016.08.014  0.244
1996 Chen W, Wetsel W, Steenbergen C, Murphy E. Effect of ischemic preconditioning and PKC activation on acidification during ischemia in rat heart. Journal of Molecular and Cellular Cardiology. 28: 871-80. PMID 8762027 DOI: 10.1006/Jmcc.1996.0082  0.242
2011 Wetsel WC. Sensing hot and cold with TRP channels. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 27: 388-98. PMID 21591901 DOI: 10.3109/02656736.2011.554337  0.242
1995 Olson BR, Scott DC, Wetsel WC, Elliot SJ, Tomic M, Stojilkovic S, Nieman LK, Wray S. Effects of insulin-like growth factors I and II and insulin on the immortalized hypothalamic GTI-7 cell line. Neuroendocrinology. 62: 155-65. PMID 8584115 DOI: 10.1159/000127000  0.24
2016 Farrell MS, McCorvy JD, Huang XP, Urban DJ, White KL, Giguere PM, Doak AK, Bernstein AI, Stout KA, Park SM, Rodriguiz RM, Gray BW, Hyatt WS, Norwood AP, Webster KA, ... ... Wetsel WC, et al. In Vitro and In Vivo Characterization of the Alkaloid Nuciferine. Plos One. 11: e0150602. PMID 26963248 DOI: 10.1371/Journal.Pone.0150602  0.234
1984 Wetsel WC, Rogers AE. Hepatic prolactin binding in female Sprague-Dawley rats fed a diet high in corn oil. Journal of the National Cancer Institute. 73: 531-6. PMID 6087010 DOI: 10.1093/Jnci/73.2.531  0.232
2022 Aryal DK, Rodriguiz RM, Nguyen NL, Pease MW, Morgan DJ, Pintar J, Fricker LD, Wetsel WC. Mice lacking proSAAS display alterations in emotion, consummatory behavior and circadian entrainment. Genes, Brain, and Behavior. e12827. PMID 35878875 DOI: 10.1111/gbb.12827  0.231
2009 Yuan L, Seo JS, Kang NS, Keinan S, Steele SE, Michelotti GA, Wetsel WC, Beratan DN, Gong YD, Lee TH, Hong J. Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse. Molecular Biosystems. 5: 927-30. PMID 19668856 DOI: 10.1039/B903036K  0.23
2012 Besnard J, Ruda GF, Setola V, Abecassis K, Rodriguiz RM, Huang XP, Norval S, Sassano MF, Shin AI, Webster LA, Simeons FR, Stojanovski L, Prat A, Seidah NG, Constam DB, ... ... Wetsel WC, et al. Automated design of ligands to polypharmacological profiles. Nature. 492: 215-20. PMID 23235874 DOI: 10.1038/Nature11691  0.228
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Wetsel WC, Gainetdinov RR, Caron MG. Reply to Belmaker et al.: GSK3β haploinsufficiency results in lithium-like effects in the forced-swim test Proceedings of the National Academy of Sciences of the United States of America. 105: E24. DOI: 10.1073/Pnas.0803026105  0.22
2022 Zhang Z, Ma Q, Velagapudi R, Barclay WE, Rodriguiz RM, Wetsel WC, Yang T, Shinohara ML, Terrando N. Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome. Frontiers in Immunology. 13: 856254. PMID 35603196 DOI: 10.3389/fimmu.2022.856254  0.218
2022 Gross JD, Kim DW, Zhou Y, Jansen D, Slosky LM, Clark NB, Ray CR, Hu X, Southall N, Wang A, Xu X, Barnaeva E, Wetsel WC, Ferrer M, Marugan JJ, et al. Discovery of a functionally selective ghrelin receptor (GHSR) ligand for modulating brain dopamine. Proceedings of the National Academy of Sciences of the United States of America. 119: e2112397119. PMID 35239443 DOI: 10.1073/pnas.2112397119  0.216
1977 Treichler FR, Wetsel WC, Lesner SA. Some characteristics of concurrent discrimination and retention by monkeys Learning and Motivation. 8: 213-228. DOI: 10.1016/0023-9690(77)90006-6  0.212
1978 Treichler FR, Wetsel WC. Pressure influences on air-licking behavior of rats Physiological Psychology. 6: 399-402. DOI: 10.3758/Bf03326747  0.208
2023 Wang Z, Li Q, Kolls BJ, Mace B, Yu S, Li X, Liu W, Chaparro E, Shen Y, Dang L, Del Águila Á, Bernstock JD, Johnson KR, Yao J, Wetsel WC, et al. Sustained overexpression of spliced X-box-binding protein-1 in neurons leads to spontaneous seizures and sudden death in mice. Communications Biology. 6: 252. PMID 36894627 DOI: 10.1038/s42003-023-04594-8  0.208
2014 Wu CL, Jain D, McNeill JN, Little D, Anderson JA, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, Guilak F. Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury. Annals of the Rheumatic Diseases. PMID 25015373 DOI: 10.1136/Annrheumdis-2014-205601  0.208
2018 McGaughey KD, Yilmaz-Swenson T, Elsayed NM, Cruz DA, Rodriguez RR, Kritzer MD, Peterchev AV, Gray M, Lewis SR, Roach J, Wetsel WC, Williamson DE. Comparative evaluation of a new magnetic bead-based DNA extraction method from fecal samples for downstream next-generation 16S rRNA gene sequencing. Plos One. 13: e0202858. PMID 30138447 DOI: 10.1371/Journal.Pone.0202858  0.206
2022 Slosky LM, Pires A, Bai Y, Clark NB, Hauser ER, Gross JD, Porkka F, Zhou Y, Chen X, Pogorelov VM, Toth K, Wetsel WC, Barak LS, Caron MG. Establishment of multi-stage intravenous self-administration paradigms in mice. Scientific Reports. 12: 21422. PMID 36503898 DOI: 10.1038/s41598-022-24740-2  0.205
2020 Monroe TO, Garrett ME, Kousi M, Rodriguiz RM, Moon S, Bai Y, Brodar SC, Soldano KL, Savage J, Hansen TF, Muzny DM, Gibbs RA, Barak L, Sullivan PF, Ashley-Koch AE, ... ... Wetsel WC, et al. PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia. Nature Communications. 11: 5903. PMID 33214552 DOI: 10.1038/s41467-020-19637-5  0.198
2020 Wang P, Velagapudi R, Kong C, Rodriguiz RM, Wetsel WC, Yang T, Berger M, Gelbard HA, Colton CA, Terrando N. Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32291962 DOI: 10.1002/Alz.12064  0.197
2023 Pogorelov VM, Martini ML, Jin J, Wetsel WC, Caron MG. Dopamine-Depleted Dopamine Transporter Knockout (DDD) Mice: Dyskinesia with L-DOPA and Dopamine D1 Agonists. Biomolecules. 13. PMID 38002340 DOI: 10.3390/biom13111658  0.196
2022 David-Bercholz J, Acker L, Caceres AI, Wu PY, Goenka S, Franklin NO, Rodriguiz RM, Wetsel WC, Devinney M, Wright MC, Zetterberg H, Yang T, Berger M, Terrando N. Conserved YKL-40 changes in mice and humans after postoperative delirium. Brain, Behavior, & Immunity - Health. 26: 100555. PMID 36457825 DOI: 10.1016/j.bbih.2022.100555  0.188
1992 Mellon PL, Wetsel WC, Windle JJ, Valença MM, Goldsmith PC, Whyte DB, Eraly SA, Negro-Vilar A, Weiner RI. Immortalized hypothalamic gonadotropin-releasing hormone neurons. Ciba Foundation Symposium. 168: 104-17; discussion 1. PMID 1330456  0.187
2021 Dong C, Ly C, Dunlap LE, Vargas MV, Sun J, Hwang IW, Azinfar A, Oh WC, Wetsel WC, Olson DE, Tian L. Psychedelic-inspired drug discovery using an engineered biosensor. Cell. PMID 33915107 DOI: 10.1016/j.cell.2021.03.043  0.185
2022 Chandra R, Aryal DK, Douros JD, Shahid R, Davis SJ, Campbell JE, Ilkayeya O, White PJ, Rodriguez R, Newgard CB, Wetsel WC, Liddle RA. Ildr1 gene deletion protects against diet-induced obesity and hyperglycemia. Plos One. 17: e0270329. PMID 35749484 DOI: 10.1371/journal.pone.0270329  0.181
2020 Fricker LD, Tashima AK, Fakira AK, Hochgeschwender U, Wetsel WC, Devi LA. Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary. Cell Chemical Biology. PMID 33217339 DOI: 10.1016/j.chembiol.2020.11.003  0.18
2022 Free RB, Nilson AN, Boldizsar NM, Doyle TB, Rodriguiz RM, Pogorelov VM, Machino M, Lee KH, Bertz JW, Xu J, Lim HD, Dulcey AE, Mach RH, Woods JH, Lane JR, ... ... Wetsel WC, et al. Identification and Characterization of ML321: A Novel and Highly Selective D Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity. Acs Pharmacology & Translational Science. 6: 151-170. PMID 36654757 DOI: 10.1021/acsptsci.2c00202  0.174
2024 Kim J, Bustamante E, Sotonyi P, Maxwell ND, Parameswaran P, Kent JK, Wetsel WC, Soderblom EJ, Rácz B, Soderling SH. Presynaptic Rac1 in the hippocampus selectively regulates working memory. Biorxiv : the Preprint Server For Biology. PMID 38562715 DOI: 10.1101/2024.03.18.585488  0.159
1993 Blobe GC, Sachs CW, Khan WA, Fabbro D, Stabel S, Wetsel WC, Obeid LM, Fine RL, Hannun YA. Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha. The Journal of Biological Chemistry. 268: 658-64. PMID 8093247  0.151
1995 Bouché M, Zappelli F, Polimeni M, Adamo S, Wetsel WC, Senni MI, Molinaro M. Rapid activation and down-regulation of protein kinase C alpha in 12-O-Tetradecanoylphorbol-13-acetate-induced differentiation of human rhabdomyosarcoma cells. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 6: 845-52. PMID 7547506  0.147
2023 Barzi M, Johnson CG, Chen T, Rodriguiz RM, Hemmingsen M, Gonzalez TJ, Rosales A, Beasley J, Peck CK, Ma Y, Stiles AR, Wood TC, Maeso-Diaz R, Diehl AM, Young SP, ... ... Wetsel WC, et al. Rescue of glutaric aciduria type I in mice by liver-directed therapies. Science Translational Medicine. 15: eadf4086. PMID 37075130 DOI: 10.1126/scitranslmed.adf4086  0.142
2021 Martini ML, Ray C, Yu X, Liu J, Pogorelov VM, Wetsel WC, Huang XP, McCorvy JD, Caron MG, Jin J. Addition to "Designing Functionally Selective Noncatechol Dopamine D Receptor Agonists with Potent In Vivo Antiparkinsonian Activity". Acs Chemical Neuroscience. PMID 33830725 DOI: 10.1021/acschemneuro.1c00186  0.139
2022 Hornburg KJ, Slosky LM, Cofer G, Cook J, Qi Y, Porkka F, Clark NB, Pires A, Petrella JR, White LE, Wetsel WC, Barak L, Caron MG, Johnson GA. Prenatal Heroin Exposure Alters Brain Morphology and Connectivity in Adolescent Mice. Nmr in Biomedicine. e4842. PMID 36259728 DOI: 10.1002/nbm.4842  0.137
1997 Ma YJ, Berg-von der Emde K, Rage F, Wetsel WC, Ojeda SR. Hypothalamic astrocytes respond to transforming growth factor-alpha with the secretion of neuroactive substances that stimulate the release of luteinizing hormone-releasing hormone. Endocrinology. 138: 19-25. PMID 8977380 DOI: 10.1210/endo.138.1.4863  0.136
2022 Kaplan AL, Confair DN, Kim K, Barros-Álvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, ... ... Wetsel WC, et al. Bespoke library docking for 5-HT receptor agonists with antidepressant activity. Nature. PMID 36171289 DOI: 10.1038/s41586-022-05258-z  0.132
2013 Wetsel WC, Moy SS, Jiang YH. Mouse Behavioral Models for Autism Spectrum Disorders The Neuroscience of Autism Spectrum Disorders. 363-378. DOI: 10.1016/B978-0-12-391924-3.00026-0  0.124
2023 Singh I, Seth A, Billesbølle CB, Braz J, Rodriguiz RM, Roy K, Bekele B, Craik V, Huang XP, Boytsov D, Pogorelov VM, Lak P, O'Donnell H, Sandtner W, Irwin JJ, ... ... Wetsel WC, et al. Structure-based discovery of conformationally selective inhibitors of the serotonin transporter. Cell. PMID 37137306 DOI: 10.1016/j.cell.2023.04.010  0.117
2022 Yang T, Velagapudi R, Kong C, Ko U, Kumar V, Brown P, Franklin NO, Zhang X, Caceres AI, Min H, Filiano AJ, Rodriguiz RM, Wetsel WC, Varghese S, Terrando N. Protective effects of omega-3 fatty acids in a blood-brain barrier-on-chip model and on postoperative delirium-like behaviour in mice. British Journal of Anaesthesia. PMID 35778276 DOI: 10.1016/j.bja.2022.05.025  0.1
1994 Ghalayini AJ, Koutz CA, Wetsel WC, Hannun YA, Anderson RE. Immunolocalization of PKC zeta in rat photoreceptor inner segments. Current Eye Research. 13: 145-50. PMID 8194361 DOI: 10.3109/02713689409042409  0.1
1993 Khan WA, Blobe G, Halpern A, Taylor W, Wetsel WC, Burns D, Loomis C, Hannun YA. Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets. The Journal of Biological Chemistry. 268: 5063-8. PMID 8444883  0.099
1984 Wetsel WC, Rogers AE, Rutledge A, Leavitt WW. Absence of an effect of dietary corn oil content on plasma prolactin, progesterone, and 17 beta-estradiol in female Sprague-Dawley rats. Cancer Research. 44: 1420-5. PMID 6423274  0.094
2000 Sarkis EH, Gainetdinov RR, Wetsel WC, Caron MG. 'Model' behavior [4] (multiple letters) Science. 287: 2160-2162. PMID 10744536  0.085
1981 Rogers AE, Wetsel WC. Mammary carcinogenesis in rats fed different amounts and types of fat. Cancer Research. 41: 3735-7. PMID 6790168  0.078
2008 Wetsel W. I-34 BEHAVIORAL METHODS FOR ASSESSING OA AND PAIN IN MOUSE MODELS Osteoarthritis and Cartilage. 16: S11. DOI: 10.1016/S1063-4584(08)60044-8  0.077
1983 Rogers A, Wetsel W, Rutledge A. 132 Failure of high fat diet to alter plasma prolactin, estrogen or progesterone content in rats Journal of Steroid Biochemistry. 19: 44. DOI: 10.1016/0022-4731(83)91632-1  0.071
2013 Sassano MF, Allen JA, Jin J, Setola V, Wetsel WC, Caron MG, Roth BL. D2 Functionally Selective Ligands: Novel Therapeutics? Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 105. DOI: 10.1016/B978-0-12-800044-1.00091-X  0.071
1980 Wetsel WC, Rogers AE. Effect of dietary fat on mammary carcinogenesis and serum prolactin in rats Federation Proceedings. 39: 3248.  0.07
1981 Wetsel WC, Rogers AE, Newberne PM. Dietary fat and DMBA mammary carcinogenesis in rats. Cancer Detection and Prevention. 4: 535-43. PMID 6819892  0.063
1984 Wetsel WC, Rogers AE. Hepatic prolactin binding in female rats fed control or high corn oil diets Federation Proceedings. 43: no. 2379.  0.055
2019 McGaughey KD, Yilmaz-Swenson T, Elsayed NM, Cruz DA, Rodriguez RM, Kritzer MD, Peterchev AV, Gray M, Lewis SR, Roach J, Wetsel WC, Williamson DE. Correction: Comparative evaluation of a new magnetic bead-based DNA extraction method from fecal samples for downstream next-generation 16S rRNA gene sequencing. Plos One. 14: e0212712. PMID 30779792 DOI: 10.1371/journal.pone.0212712  0.03
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