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Xiang-yan Chen, Ph.D. - Publications

Affiliations: 
2006 The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Neuroscience Biology, Medical Biophysics, Pathology
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65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Li J, Zheng L, Yang WJ, Sze-To CY, Leung TW, Chen XY. Plaque Wall Distribution Pattern of the Atherosclerotic Middle Cerebral Artery Associates With the Circle of Willis Completeness. Frontiers in Neurology. 11: 599459. PMID 33505347 DOI: 10.3389/fneur.2020.599459  0.312
2020 Wu X, Bos D, Ren L, Leung TW, Chu WC, Wong LKS, Abrigo J, Chen XY. Intracranial Arterial Calcification Relates to Long-Term Risk of Recurrent Stroke and Post-stroke Mortality. Frontiers in Neurology. 11: 559158. PMID 33162927 DOI: 10.3389/fneur.2020.559158  0.426
2020 Yang WJ, Abrigo J, Soo YO, Wong S, Wong KS, Leung TW, Chu WC, Chen XY. Regression of Plaque Enhancement Within Symptomatic Middle Cerebral Artery Atherosclerosis: A High-Resolution MRI Study. Frontiers in Neurology. 11: 755. PMID 32849214 DOI: 10.3389/fneur.2020.00755  0.352
2019 Hu MZ, Wang AR, Zhao ZY, Chen XY, Li YB, Liu B. Antidepressant-like effects of paeoniflorin on post-stroke depression in a rat model. Neurological Research. 1-10. PMID 30759063 DOI: 10.1080/01616412.2019.1576361  0.314
2018 Zhang Z, Chen XY, Baum L, Ng HK, Mok V, Wong KS. Association Between the Apolipoprotein E Gene Polymorphism and Atherosclerotic Middle Cerebral Artery Stenosis. The Neurologist. 23: 47-50. PMID 29494434 DOI: 10.1097/Nrl.0000000000000164  0.343
2018 Wu X, Wang L, Zhong J, Ko J, Shi L, Soo Y, Leung T, Wong KS, Abrigo J, Chen X. Impact of intracranial artery calcification on cerebral hemodynamic changes. Neuroradiology. PMID 29426978 DOI: 10.1007/S00234-018-1988-2  0.455
2018 Wu X, Chen X, Wang L, Chu WC, Ren L, Wong K, Abrigo J, Leung TW. Abstract WP198: Intracranial Arterial Calcification Predicts Stroke Recurrence: an 11-year Follow-up Study Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Wp198  0.496
2018 Yang W, Zheng L, Wu X, Niu C, Leung TW, Chen X. Abstract WMP44: Postmortem Study Exploring Distribution and Patterns of Intracranial Arterial Calcification Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Wmp44  0.372
2017 Xiong L, Tian G, Leung H, Soo YOY, Chen X, Ip VHL, Mok VCT, Chu WCW, Wong KS, Leung TWH. Autonomic Dysfunction Predicts Clinical Outcomes After Acute Ischemic Stroke: A Prospective Observational Study. Stroke. PMID 29203690 DOI: 10.1161/Strokeaha.117.019312  0.419
2017 Yang WJ, Fisher M, Zheng L, Niu CB, Paganini-Hill A, Zhao HL, Xu Y, Wong KS, Ng HK, Chen XY. Histological Characteristics of Intracranial Atherosclerosis in a Chinese Population: A Postmortem Study. Frontiers in Neurology. 8: 488. PMID 28993752 DOI: 10.3389/fneur.2017.00488  0.305
2017 Yang WJ, Wong KS, Chen XY. Intracranial Atherosclerosis: from Microscopy to High-Resolution Magnetic Resonance Imaging. Journal of Stroke. PMID 28877564 DOI: 10.5853/Jos.2016.01956  0.354
2017 Soo Y, Chan N, Leung KT, Chen XY, Mok V, Wong L, Leung T. Age-specific trends of atrial fibrillation-related ischaemic stroke and transient ischaemic attack, anticoagulant use and risk factor profile in Chinese population: a 15-year study. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28550068 DOI: 10.1136/Jnnp-2017-315735  0.414
2017 Xiong L, Tian G, Wang L, Lin W, Chen X, Leung TW, Soo YO, Wong LK. External Counterpulsation Increases Beat-to-Beat Heart Rate Variability in Patients with Ischemic Stroke. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. PMID 28396189 DOI: 10.1016/J.Jstrokecerebrovasdis.2017.03.007  0.473
2017 Xiong L, Tian G, Lin W, Wang W, Wang L, Leung T, Mok V, Liu J, Chen X, Wong KS. Is Dynamic Cerebral Autoregulation Bilaterally Impaired after Unilateral Acute Ischemic Stroke? Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. PMID 28262564 DOI: 10.1016/J.Jstrokecerebrovasdis.2016.12.024  0.49
2017 Chen XY, Wang Q, Wang X, Wong KS. Clinical Features of Thalamic Stroke. Current Treatment Options in Neurology. 19: 5. PMID 28251587 DOI: 10.1007/s11940-017-0441-x  0.346
2016 Chen XY, Fisher M. Pathological Characteristics. Frontiers of Neurology and Neuroscience. 40: 21-33. PMID 27960191 DOI: 10.1159/000448267  0.345
2016 Wu XH, Chen XY, Fan YH, Leung TW, Wong KS. High Extent of Intracranial Carotid Artery Calcification Is Associated with Downstream Microemboli in Stroke Patients. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. PMID 27818028 DOI: 10.1016/J.Jstrokecerebrovasdis.2016.10.007  0.507
2016 Lan L, Leng X, Abrigo J, Ip V, Soo YO, Leung T, Chen X, Wong KS. Cerebral perfusion difference between hemispheres with symptomatic and asymptomatic intracranial arterial stenosis. International Journal of Stroke : Official Journal of the International Stroke Society. PMID 27765898 DOI: 10.1177/1747493016676284  0.375
2016 Fang H, Chen XY, Song B, Cheng B, Xu YM, Wong KS, Ho SS. Intracranial collateral flow estimated by Color Velocity Imaging Quantification Ultrasound: a Protector of Recurrent Stroke in Patient with Carotid Stenosis? Current Neurovascular Research. PMID 27538891  0.422
2016 Dieleman N, Yang W, Abrigo JM, Chu WC, van der Kolk AG, Siero JC, Wong KS, Hendrikse J, Chen XY. Magnetic Resonance Imaging of Plaque Morphology, Burden, and Distribution in Patients With Symptomatic Middle Cerebral Artery Stenosis. Stroke; a Journal of Cerebral Circulation. PMID 27301944 DOI: 10.1161/STROKEAHA.116.013007  0.357
2016 Wu XH, Chen XY, Wang LJ, Wong KS. Intracranial Artery Calcification and Its Clinical Significance. Journal of Clinical Neurology (Seoul, Korea). PMID 27165425  0.392
2016 Tian G, Xiong L, Lin W, Han J, Chen X, Leung TW, Soo YO, Wong LK. External Counterpulsation Reduces Beat-to-Beat Blood Pressure Variability When Augmenting Blood Pressure and Cerebral Blood Flow in Ischemic Stroke. Journal of Clinical Neurology (Seoul, Korea). PMID 27095525 DOI: 10.3988/Jcn.2016.12.3.308  0.441
2016 Fu X, Huang C, Wong KS, Chen X, Gao Q. A New Method for Cerebral Arterial Stiffness by Measuring Pulse Wave Velocity Using Transcranial Doppler. Journal of Atherosclerosis and Thrombosis. PMID 27052663 DOI: 10.5551/Jat.33555  0.335
2016 Fang H, Song B, Cheng B, Wong KS, Xu YM, Ho SS, Chen XY. Compensatory patterns of collateral flow in stroke patients with unilateral and bilateral carotid stenosis. Bmc Neurology. 16: 39. PMID 26987874 DOI: 10.1186/s12883-016-0560-0  0.397
2015 Yang WJ, Chen XY, Zhao HL, Niu CB, Xu Y, Wong KS, Ng HK. In Vitro Assessment of Histology Verified Intracranial Atherosclerotic Disease by 1.5T Magnetic Resonance Imaging: Concentric or Eccentric? Stroke; a Journal of Cerebral Circulation. PMID 26628387 DOI: 10.1161/Strokeaha.115.011086  0.322
2015 Nam HS, Scalzo F, Leng X, Ip HL, Lee HS, Fan F, Chen X, Soo Y, Miao Z, Liu L, Feldmann E, Leung T, Wong KS, Liebeskind DS. Hemodynamic Impact of Systolic Blood Pressure and Hematocrit Calculated by Computational Fluid Dynamics in Patients with Intracranial Atherosclerosis. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 26598796 DOI: 10.1111/Jon.12314  0.315
2015 Xiong L, Lin W, Han J, Chen X, Leung TW, Soo YO, Wong LK. A retrospective pilot study of correlation of cerebral augmentation effects of external counterpulsation with functional outcome after acute ischaemic stroke. Bmj Open. 5: e009233. PMID 26351195 DOI: 10.1136/Bmjopen-2015-009233  0.491
2015 Zhong J, Chen XY, Leung TW, Ou A, Shi X, Cai Y, Huang Y, Wong KS. Significance of Raised Flow Velocity in Basilar Artery in Patients with Acute Ischemic Stroke: Focal Stenosis, Coexistent Stenosis, and Collateral Flow. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 25940508 DOI: 10.1111/Jon.12245  0.473
2015 Xiong L, Lin W, Han J, Chen X, Leung T, Soo Y, Wong KS. Enhancing cerebral perfusion with external counterpulsation after ischaemic stroke: how long does it last? Journal of Neurology, Neurosurgery, and Psychiatry. PMID 25934015 DOI: 10.1136/Jnnp-2014-309842  0.488
2015 Xu JH, Huang YM, Ling W, Li Y, Wang M, Chen XY, Sui Y, Zhao HL. Wen Dan Decoction for hemorrhagic stroke and ischemic stroke. Complementary Therapies in Medicine. 23: 298-308. PMID 25847568 DOI: 10.1016/j.ctim.2015.01.001  0.391
2015 Fu J, Tang J, Yang J, Chen X, Chen Y, Leung TW, Mok V, Soo Y, Wong KL. Adding computed tomography and transcranial Doppler findings to the ABCD2 score to predict long-term risk of stroke after transient ischaemic attack or minor stroke. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 520-6. PMID 25444458 DOI: 10.1111/Ene.12606  0.435
2014 Chen XY, Tang T, Wong KS. RNA interference therapy: a new solution for intracranial atherosclerosis? Annals of Translational Medicine. 2: 79. PMID 25333054 DOI: 10.3978/j.issn.2305-5839.2014.07.11  0.368
2014 Duan JG, Chen XY, Lau A, Wong A, Thomas GN, Tomlinson B, Liu R, Chan JC, Leung TW, Mok V, Wong KS. Long-term risk of cardiovascular disease among type 2 diabetic patients with asymptomatic intracranial atherosclerosis: a prospective cohort study. Plos One. 9: e106623. PMID 25192283 DOI: 10.1371/Journal.Pone.0106623  0.314
2014 Leng X, Scalzo F, Ip HL, Johnson M, Fong AK, Fan FS, Chen X, Soo YO, Miao Z, Liu L, Feldmann E, Leung TW, Liebeskind DS, Wong KS. Computational fluid dynamics modeling of symptomatic intracranial atherosclerosis may predict risk of stroke recurrence. Plos One. 9: e97531. PMID 24818753 DOI: 10.1371/Journal.Pone.0097531  0.454
2014 Lin W, Xiong L, Han J, Leung H, Leung T, Soo Y, Chen X, Wong KS. Increasing pressure of external counterpulsation augments blood pressure but not cerebral blood flow velocity in ischemic stroke. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 21: 1148-52. PMID 24508283 DOI: 10.1016/J.Jocn.2013.09.023  0.416
2014 Xiong Y, Wong A, Wong K, Chu WC, Hu X, Chen X, Wong KS, Wong ST, Liu X, Mok V. Predictors for cortical gray matter volume in stroke patients with confluent white matter changes. Journal of the Neurological Sciences. 338: 169-73. PMID 24468539 DOI: 10.1016/J.Jns.2013.12.044  0.44
2014 Lin W, Xiong L, Han J, Leung T, Leung H, Chen X, Wong KS. Hemodynamic effect of external counterpulsation is a different measure of impaired cerebral autoregulation from vasoreactivity to breath-holding. European Journal of Neurology. 21: 326-31. PMID 24313861 DOI: 10.1111/Ene.12314  0.466
2013 Li JJ, Chen XY, Soo Y, Abrigo JM, Leung TW, Wong E, Mok V, Cheung JS, Ahuja AT, Zeng JS, Wong KS. Persistent benign oligemia causes CT perfusion mismatch in patients with intracranial large artery occlusive disease during subacute stroke. Cns Neuroscience & Therapeutics. 19: 635-7. PMID 23876019 DOI: 10.1111/Cns.12133  0.476
2013 Lin W, Han J, Chen X, Xiong L, Leung HW, Leung TW, Soo Y, Wong LK. Predictors of good functional outcome in counterpulsation-treated recent ischaemic stroke patients. Bmj Open. 3. PMID 23794561 DOI: 10.1136/Bmjopen-2013-002932  0.429
2013 Leng XY, Chen XY, Chook P, Xiong L, Lin WH, Liu JY, Tomlinson B, Thomas GN, Lam TH, Lam KS, Cheung BM, Wong KS. Correlation of large artery intracranial occlusive disease with carotid intima-media thickness and presence of carotid plaque. Stroke; a Journal of Cerebral Circulation. 44: 68-72. PMID 23168454 DOI: 10.1161/Strokeaha.112.675652  0.4
2013 Wang X, Lin WH, Zhao YD, Chen XY, Leung TW, Chen C, Fu J, Markus H, Hao Q, Wong KS. The effectiveness of dual antiplatelet treatment in acute ischemic stroke patients with intracranial arterial stenosis: a subgroup analysis of CLAIR study. International Journal of Stroke : Official Journal of the International Stroke Society. 8: 663-8. PMID 22883712 DOI: 10.1111/J.1747-4949.2012.00828.X  0.383
2013 Xiong L, Leung HH, Chen XY, Han JH, Leung TW, Soo YO, Chan AY, Lau AY, Wong LK. Comprehensive assessment for autonomic dysfunction in different phases after ischemic stroke. International Journal of Stroke : Official Journal of the International Stroke Society. 8: 645-51. PMID 22759410 DOI: 10.1111/J.1747-4949.2012.00829.X  0.346
2013 Gao Q, Fu X, Wei JW, Chen X, Huang Y, Wang J, Anderson CS, Wong KS. Use of oral anticoagulation among stroke patients with atrial fibrillation in China: the ChinaQUEST (Quality evaluation of stroke care and treatment) registry study. International Journal of Stroke : Official Journal of the International Stroke Society. 8: 150-4. PMID 22168348 DOI: 10.1111/J.1747-4949.2011.00716.X  0.451
2013 Xiong YY, Mok V, Wong A, Leung T, Chen XY, Chu WCW, Soo Y, Fu JH, Ding D, Hong Z, Wong KS. Evaluation of Age-Related White Matter Changes Using Transcranial Doppler Ultrasonography Journal of Neuroimaging. 23: 53-57. PMID 21914030 DOI: 10.1111/J.1552-6569.2011.00649.X  0.304
2012 Lin W, Xiong L, Han J, Leung TW, Soo YO, Chen X, Wong KS. External counterpulsation augments blood pressure and cerebral flow velocities in ischemic stroke patients with cerebral intracranial large artery occlusive disease. Stroke; a Journal of Cerebral Circulation. 43: 3007-11. PMID 22996956 DOI: 10.1161/Strokeaha.112.659144  0.491
2012 Wang Q, Chen C, Chen XY, Han JH, Soo Y, Leung TW, Mok V, Wong KS. Low-molecular-weight heparin and early neurologic deterioration in acute stroke caused by large artery occlusive disease. Archives of Neurology. 69: 1454-60. PMID 22893265 DOI: 10.1001/Archneurol.2012.1633  0.419
2012 Mok V, Xiong Y, Wong KK, Wong A, Schmidt R, Chu WW, Hu X, Lung Leung EY, Chen S, Chen Y, Tang WK, Chen X, Ho CL, Wong KS, Wong ST. Predictors for cognitive decline in patients with confluent white matter hyperintensities. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: S96-S103. PMID 22651941 DOI: 10.1016/J.Jalz.2011.10.004  0.428
2012 Xiong L, Leung H, Chen XY, Han JH, Leung T, Soo Y, Wong E, Chan A, Lau A, Wong KS. Preliminary findings of the effects of autonomic dysfunction on functional outcome after acute ischemic stroke. Clinical Neurology and Neurosurgery. 114: 316-20. PMID 22088362 DOI: 10.1016/j.clineuro.2011.10.037  0.333
2012 Wang QS, Chen C, Chen XY, Han JH, Soo Y, Leung TW, Mok V, Wong KS. Low-molecular-weight heparin versus aspirin for acute ischemic stroke with large artery occlusive disease: subgroup analyses from the Fraxiparin in Stroke Study for the treatment of ischemic stroke (FISS-tris) study. Stroke; a Journal of Cerebral Circulation. 43: 346-9. PMID 22076004 DOI: 10.1161/Strokeaha.111.628347  0.408
2011 Fu X, Wong KS, Wei JW, Chen X, Lin Y, Zeng J, Huang R, Gao Q. Factors associated with severity on admission and in-hospital mortality after primary intracerebral hemorrhage in China. International Journal of Stroke : Official Journal of the International Stroke Society. 8: 73-9. PMID 22151822 DOI: 10.1111/J.1747-4949.2011.00712.X  0.35
2011 Mok V, Wong KK, Xiong Y, Wong A, Schmidt R, Chu W, Hu X, Leung EY, Chen S, Chen Y, Tang WK, Chen X, Ho CL, Wong KS, Wong ST. Cortical and frontal atrophy are associated with cognitive impairment in age-related confluent white-matter lesion. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 52-7. PMID 20826875 DOI: 10.1136/Jnnp.2009.201665  0.328
2010 Fu JH, Chen YK, Chen XY, Mok V, Wong KS. Coexisting small vessel disease predicts poor long-term outcome in stroke patients with intracranial large artery atherosclerosis. Cerebrovascular Diseases (Basel, Switzerland). 30: 433-9. PMID 20720413 DOI: 10.1159/000319574  0.349
2010 Chen XY, Thomas GN, Chen YK, Chan JC, Wong KS. Atherosclerotic vascular disease rather than metabolic syndrome predicts ischemic stroke in diabetic patients. Cerebrovascular Diseases (Basel, Switzerland). 30: 374-9. PMID 20693792 DOI: 10.1159/000319570  0.303
2010 Xiong Y, Mok V, Wong A, Chen X, Chu WC, Fan Y, Soo Y, Wong KS. The age-related white matter changes scale correlates with cognitive impairment. European Journal of Neurology. 17: 1451-6. PMID 20491886 DOI: 10.1111/J.1468-1331.2010.03078.X  0.309
2010 Yang J, Fu JH, Chen XY, Chen YK, Leung TW, Mok V, Soo Y, Wong KS. Validation of the ABCD2 score to identify the patients with high risk of late stroke after a transient ischemic attack or minor ischemic stroke. Stroke; a Journal of Cerebral Circulation. 41: 1298-300. PMID 20413737 DOI: 10.1161/Strokeaha.110.578757  0.479
2010 You Y, Hao Q, Leung T, Mok V, Chen X, Lau A, Leung H, Wong KS. Detection of the siphon internal carotid artery stenosis: transcranial Doppler versus digital subtraction angiography. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 20: 234-9. PMID 19889048 DOI: 10.1111/J.1552-6569.2009.00434.X  0.333
2009 Chen Y, Chen X, Xiao W, Mok VC, Wong KS, Tang WK. Frontal lobe atrophy is associated with small vessel disease in ischemic stroke patients. Clinical Neurology and Neurosurgery. 111: 852-7. PMID 19744770 DOI: 10.1016/J.Clineuro.2009.08.019  0.475
2009 Chen Y, Chen X, Mok VC, Lam WW, Wong KS, Tang WK. Poststroke depression in patients with small subcortical infarcts. Clinical Neurology and Neurosurgery. 111: 256-60. PMID 19036495 DOI: 10.1016/J.Clineuro.2008.10.008  0.379
2008 Thomas GN, Chen XY, Lin JW, Tomlinson B, Lam WW, Liu R, Yeung VT, Chan JC, Wong KS. Middle cerebral artery stenosis increased the risk of vascular disease mortality among type 2 diabetic patients. Cerebrovascular Diseases (Basel, Switzerland). 25: 261-7. PMID 18270486 DOI: 10.1159/000116303  0.407
2008 Chen XY, Wong KS, Lam WW, Zhao HL, Ng HK. Middle cerebral artery atherosclerosis: histological comparison between plaques associated with and not associated with infarct in a postmortem study. Cerebrovascular Diseases (Basel, Switzerland). 25: 74-80. PMID 18033961 DOI: 10.1159/000111525  0.378
2007 Chen XY, Lam WW, Ng HK, Fan YH, Wong KS. Intracranial artery calcification: a newly identified risk factor of ischemic stroke. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 17: 300-3. PMID 17894617 DOI: 10.1111/J.1552-6569.2007.00158.X  0.434
2007 Baum L, Chen X, Cheung WS, Cheung CK, Cheung LW, Chiu KF, Wen HM, Poon P, Woo KS, Ng HK, Wong KS. Polymorphisms and vascular cognitive impairment after ischemic stroke. Journal of Geriatric Psychiatry and Neurology. 20: 93-9. PMID 17548779 DOI: 10.1177/0891988706298627  0.437
2006 Baum L, Ng HK, Wong KS, Tomlinson B, Rainer TH, Chen X, Cheung WS, Tang J, Tam WW, Goggins W, Tong CS, Chan DK, Thomas GN, Chook P, Woo KS. Associations of apolipoprotein E exon 4 and lipoprotein lipase S447X polymorphisms with acute ischemic stroke and myocardial infarction. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 44: 274-81. PMID 16519597 DOI: 10.1515/Cclm.2006.047  0.4
2006 Baum L, Ng HK, Woo KS, Tomlinson B, Rainer TH, Chen X, Cheung WS, Chan DK, Thomas GN, Tong CS, Wong KS. Paraoxonase 1 gene Q192R polymorphism affects stroke and myocardial infarction risk. Clinical Biochemistry. 39: 191-5. PMID 16472799 DOI: 10.1016/J.Clinbiochem.2006.01.010  0.408
2004 Baum L, Wong KS, Ng HK, Tomlinson B, Rainer TH, Chan DK, Thomas GN, Chen X, Poon P, Cheung WS, Woo KS. Methylenetetrahydrofolate reductase gene A222V polymorphism and risk of ischemic stroke. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 42: 1370-6. PMID 15576298 DOI: 10.1515/Cclm.2004.256  0.465
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