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Stephen M. Lukasik, Ph.D. - Publications

Affiliations: 
2006 University of Virginia, Charlottesville, VA 
Area:
Biochemistry, General Biophysics, Molecular Biology
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Freed DM, Lukasik SM, Sikora A, Mokdad A, Cafiso DS. Monomeric TonB and the Ton box are required for the formation of a high-affinity transporter-TonB complex. Biochemistry. 52: 2638-48. PMID 23517233 DOI: 10.1021/Bi3016108  0.373
2012 Freed DM, Lukasik SM, Mokdad A, Cafiso DS. Energy Transduction Between Membranes: Characterization of the Interaction Between TonB and its Cognate Transporters Biophysical Journal. 102: 626a. DOI: 10.1016/J.Bpj.2011.11.3411  0.303
2010 Cierpicki T, Risner LE, Grembecka J, Lukasik SM, Popovic R, Omonkowska M, Shultis DD, Zeleznik-Le NJ, Bushweller JH. Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia. Nature Structural & Molecular Biology. 17: 62-8. PMID 20010842 DOI: 10.1038/Nsmb.1714  0.717
2009 Risner L, Cierpicki T, Grembecka J, Lukasik SM, Popovic R, Shultis DS, Zeleznik-Le NJ, Bushweller JH. Structural Basis for MLL Cxxc Domain Protection against CpG DNA Methylation and the Essential Role of This Function in MLL-AF9 Leukemia. Blood. 114: 763-763. DOI: 10.1182/Blood.V114.22.763.763  0.702
2008 Zhou Y, Cierpicki T, Jimenez RH, Lukasik SM, Ellena JF, Cafiso DS, Kadokura H, Beckwith J, Bushweller JH. NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Molecular Cell. 31: 896-908. PMID 18922471 DOI: 10.1016/J.Molcel.2008.08.028  0.641
2007 Lukasik SM, Ho KW, Cafiso DS. Molecular basis for substrate-dependent transmembrane signaling in an outer-membrane transporter. Journal of Molecular Biology. 370: 807-11. PMID 17555764 DOI: 10.1016/J.Jmb.2007.05.040  0.36
2006 Li Z, Lukasik SM, Liu Y, Grembecka J, Bielnicka I, Bushweller JH, Speck NA. A mutation in the S-switch region of the Runt domain alters the dynamics of an allosteric network responsible for CBFbeta regulation. Journal of Molecular Biology. 364: 1073-83. PMID 17059830 DOI: 10.1016/J.Jmb.2006.10.002  0.759
2006 Liu Y, Cheney MD, Gaudet JJ, Chruszcz M, Lukasik SM, Sugiyama D, Lary J, Cole J, Dauter Z, Minor W, Speck NA, Bushweller JH. The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity. Cancer Cell. 9: 249-60. PMID 16616331 DOI: 10.1016/J.Ccr.2006.03.012  0.711
2006 Lukasik SM, Cierpicki T, Borloz M, Grembecka J, Everett A, Bushweller JH. High resolution structure of the HDGF PWWP domain: a potential DNA binding domain. Protein Science : a Publication of the Protein Society. 15: 314-23. PMID 16384999 DOI: 10.1110/Ps.051751706  0.732
2005 Brautigan DL, Brown M, Grindrod S, Chinigo G, Kruszewski A, Lukasik SM, Bushweller JH, Horal M, Keller S, Tamura S, Heimark DB, Price J, Larner AN, Larner J. Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action. Biochemistry. 44: 11067-73. PMID 16101290 DOI: 10.1021/Bi0508845  0.565
2005 Cheney MD, Liu Y, Gaudet JJ, Chruszcz M, Lukasik SM, Sugiyama D, Lary J, Cole J, Dauter Z, Minor W, Speck NA, Bushweller JH. Structural and Functional Characterization of the NHR2 and Runt Domains of AML1/ETO. Blood. 106: 2854-2854. DOI: 10.1182/Blood.V106.11.2854.2854  0.75
2005 Bushweller JH, Lukasik SM, Speck NA. The CBFb-SMMHC Oncoprotein Inhibits Binding of the Runx1 Runt Domain to DNA. Blood. 106: 2709-2709. DOI: 10.1182/Blood.V106.11.2709.2709  0.736
2004 Yan J, Liu Y, Lukasik SM, Speck NA, Bushweller JH. CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium. Nature Structural & Molecular Biology. 11: 901-6. PMID 15322525 DOI: 10.1038/Nsmb819  0.74
2003 Zhang L, Lukasik SM, Speck NA, Bushweller JH. Structural and functional characterization of Runx1, CBF beta, and CBF beta-SMMHC. Blood Cells, Molecules & Diseases. 30: 147-56. PMID 12732176 DOI: 10.1016/S1079-9796(03)00022-6  0.729
2002 Lukasik SM, Zhang L, Corpora T, Tomanicek S, Li Y, Kundu M, Hartman K, Liu PP, Laue TM, Biltonen RL, Speck NA, Bushweller JH. Altered affinity of CBF beta-SMMHC for Runx1 explains its role in leukemogenesis. Nature Structural Biology. 9: 674-9. PMID 12172539 DOI: 10.1038/Nsb831  0.676
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