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225/455 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Neidhardt L, Cloots E, Friemel N, Weiss CAM, Harding HP, McLaughlin SH, Janssens S, Ron D. The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells. The Embo Journal. PMID 38177498 DOI: 10.1038/s44318-023-00014-z  0.327
2022 Perera LA, Ron D. AMPylation and Endoplasmic Reticulum Protein Folding Homeostasis. Cold Spring Harbor Perspectives in Biology. PMID 36041787 DOI: 10.1101/cshperspect.a041265  0.309
2019 De Franco E, Caswell R, Johnson MB, Wakeling MN, Zung A, Dũng VC, Bích Ngọc CT, Goonetilleke R, Jury MV, El-Khateeb M, Ellard S, Flanagan SE, Ron D, Hattersley AT. Mutations in Affecting eIF2 Signaling Cause Neonatal/Early Onset Diabetes and Transient Hepatic Dysfunction. Diabetes. PMID 31882561 DOI: 10.2337/Db19-1029  0.34
2019 Amin-Wetzel N, Neidhardt L, Yan Y, Mayer MP, Ron D. Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR. Elife. 8. PMID 31873072 DOI: 10.2210/Pdb6Shc/Pdb  0.425
2019 Harding HP, Ordonez A, Allen F, Parts L, Inglis AJ, Williams RL, Ron D. The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells. Elife. 8. PMID 31749445 DOI: 10.7554/Elife.50149  0.39
2019 Perera LA, Rato C, Yan Y, Neidhardt L, McLaughlin SH, Read RJ, Preissler S, Ron D. An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP. The Embo Journal. e102177. PMID 31531998 DOI: 10.15252/Embj.2019102177  0.381
2019 Yan Y, Rato C, Rohland L, Preissler S, Ron D. MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP. Nature Communications. 10: 541. PMID 30710085 DOI: 10.1038/S41467-019-08450-4  0.397
2019 Patel S, Alvarez-Guaita A, Melvin A, Rimmington D, Dattilo A, Miedzybrodzka EL, Cimino I, Maurin AC, Roberts GP, Meek CL, Virtue S, Sparks LM, Parsons SA, Redman LM, Bray GA, ... ... Ron D, et al. GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans. Cell Metabolism. PMID 30639358 DOI: 10.1016/J.Cmet.2018.12.016  0.351
2019 Yan Y, Rato C, Rohlan L, Preissler S, Ron D. MANF/ARMET antagonizes nucleotide exchange by the endoplasmic reticulum (ER) chaperone BiP_ Nature Communications. DOI: 10.2210/Pdb6Ha7/Pdb  0.323
2018 Preissler S, Ron D. Erratum: Early Events in the Endoplasmic Reticulum Unfolded Protein Response. Cold Spring Harbor Perspectives in Biology. 10. PMID 30510064 DOI: 10.1101/Cshperspect.A037309  0.362
2018 Preissler S, Ron D. Early Events in the Endoplasmic Reticulum Unfolded Protein Response. Cold Spring Harbor Perspectives in Biology. PMID 30396883 DOI: 10.1101/Cshperspect.A033894  0.463
2018 Holcman D, Parutto P, Chambers JE, Fantham M, Young LJ, Marciniak SJ, Kaminski CF, Ron D, Avezov E. Single particle trajectories reveal active endoplasmic reticulum luminal flow. Nature Cell Biology. PMID 30224760 DOI: 10.1016/J.Bpj.2018.11.964  0.352
2018 Crespillo-Casado A, Claes Z, Choy MS, Peti W, Bollen M, Ron D. A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α. The Journal of Biological Chemistry. PMID 29618508 DOI: 10.1074/Jbc.Ra118.002325  0.365
2018 Zyryanova AF, Weis F, Faille A, Alard AA, Crespillo-Casado A, Sekine Y, Harding HP, Allen F, Parts L, Fromont C, Fischer PM, Warren AJ, Ron D. Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B. Science (New York, N.Y.). 359: 1533-1536. PMID 29599245 DOI: 10.1126/Science.Aar5129  0.392
2017 Amin-Wetzel N, Saunders RA, Kamphuis MJ, Rato C, Preissler S, Harding HP, Ron D. A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response. Cell. 171: 1625-1637.e13. PMID 29198525 DOI: 10.1016/J.Cell.2017.10.040  0.47
2017 Preissler S, Rohland L, Yan Y, Chen R, Read RJ, Ron D. AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife. 6. PMID 29064368 DOI: 10.7554/Elife.29428  0.415
2017 Huang HW, Zeng X, Rhim T, Ron D, Ryoo HD. The requirement of IRE1-XBP1 in resolving physiological stress during Drosophila development. Journal of Cell Science. PMID 28775151 DOI: 10.1242/Jcs.203612  0.463
2017 Kono N, Amin-Wetzel N, Ron D. Generic membrane spanning features endow IRE1α with responsiveness to membrane aberrancy. Molecular Biology of the Cell. PMID 28615323 DOI: 10.1091/Mbc.E17-03-0144  0.389
2017 Crespillo-Casado A, Chambers JE, Fischer PM, Marciniak SJ, Ron D. PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz. Elife. 6. PMID 28447936 DOI: 10.7554/Elife.26109  0.419
2017 Melo EP, Lopes C, Gollwitzer P, Lortz S, Lenzen S, Mehmeti I, Kaminski CF, Ron D, Avezov E. TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2. Bmc Biology. 15: 24. PMID 28347335 DOI: 10.1186/S12915-017-0367-5  0.312
2017 Tschurtschenthaler M, Adolph TE, Ashcroft JW, Niederreiter L, Bharti R, Saveljeva S, Bhattacharyya J, Flak MB, Shih DQ, Fuhler GM, Parkes M, Kohno K, Iwawaki T, Janneke van der Woude C, Harding HP, ... ... Ron D, et al. Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis. The Journal of Experimental Medicine. PMID 28082357 DOI: 10.1084/Jem.20160791  0.38
2017 Cheah K, Wang MC, Tan TZ, Tsang KY, Leung K, Itoh N, Ron D, Chan D. Mechanisms of chondrocyte adaptation and survival under ER stress Mechanisms of Development. 145. DOI: 10.1016/J.Mod.2017.04.589  0.329
2016 Preissler S, Rato C, Perera LA, Saudek V, Ron D. FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP. Nature Structural & Molecular Biology. PMID 27918543 DOI: 10.1038/Nsmb.3337  0.433
2016 Sekine Y, Zyryanova A, Crespillo-Casado A, Amin-Wetzel N, Harding HP, Ron D. Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells. Plos One. 11: e0166278. PMID 27812215 DOI: 10.1371/Journal.Pone.0166278  0.399
2016 Stone S, Ho Y, Li X, Jamison S, Harding HP, Ron D, Lin W. Dual role of the integrated stress response in medulloblastoma tumorigenesis. Oncotarget. 7: 64124-64135. PMID 27802424 DOI: 10.18632/Oncotarget.11873  0.39
2016 Ho Y, Li X, Jamison S, Harding HP, McKinnon PJ, Ron D, Lin W. PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis. The American Journal of Pathology. PMID 27181404 DOI: 10.1016/J.Ajpath.2016.03.004  0.339
2015 Preissler S, Rato C, Chen R, Antrobus R, Ding S, Fearnley IM, Ron D. AMPylation matches BiP activity to client protein load in the endoplasmic reticulum. Elife. 4. PMID 26673894 DOI: 10.7554/Elife.12621  0.47
2015 Murakami T, Qamar S, Lin JQ, Schierle GS, Rees E, Miyashita A, Costa AR, Dodd RB, Chan FT, Michel CH, Kronenberg-Versteeg D, Li Y, Yang SP, Wakutani Y, Meadows W, ... ... Ron D, et al. ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function. Neuron. PMID 26526393 DOI: 10.1016/J.Neuron.2015.10.030  0.302
2015 Konno T, Pinho Melo E, Lopes C, Mehmeti I, Lenzen S, Ron D, Avezov E. ERO1-independent production of H2O2 within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding. The Journal of Cell Biology. 211: 253-9. PMID 26504166 DOI: 10.1083/Jcb.201506123  0.331
2015 Miyake M, Nomura A, Ogura A, Takehana K, Kitahara Y, Takahara K, Tsugawa K, Miyamoto C, Miura N, Sato R, Kurahashi K, Harding HP, Oyadomari M, Ron D, Oyadomari S. Skeletal muscle-specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21-mediated non-cell-autonomous energy metabolism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26487695 DOI: 10.1096/Fj.15-275990  0.375
2015 Preissler S, Chambers JE, Crespillo-Casado A, Avezov E, Miranda E, Perez J, Hendershot LM, Harding HP, Ron D. Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker. Elife. 4. PMID 26473973 DOI: 10.7554/Elife.08961  0.41
2015 Abdulkarim B, Nicolino M, Igoillo-Esteve M, Daures M, Romero S, Philippi A, Senée V, Lopes M, Cunha DA, Harding HP, Derbois C, Bendelac N, Hattersley AT, Eizirik DL, Ron D, et al. A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly. Diabetes. 64: 3951-62. PMID 26159176 DOI: 10.2337/Db15-0477  0.317
2015 Sekine Y, Zyryanova A, Crespillo-Casado A, Fischer PM, Harding HP, Ron D. Stress responses. Mutations in a translation initiation factor identify the target of a memory-enhancing compound. Science (New York, N.Y.). 348: 1027-30. PMID 25858979 DOI: 10.1126/Science.Aaa6986  0.385
2015 Chen R, Rato C, Yan Y, Crespillo-Casado A, Clarke HJ, Harding HP, Marciniak SJ, Read RJ, Ron D. G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases. Elife. 4. PMID 25774600 DOI: 10.7554/Elife.04871  0.331
2015 Chambers JE, Dalton LE, Clarke HJ, Malzer E, Dominicus CS, Patel V, Moorhead G, Ron D, Marciniak SJ. Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation. Elife. 4. PMID 25774599 DOI: 10.7554/Elife.04872  0.355
2015 Halliday M, Radford H, Sekine Y, Moreno J, Verity N, le Quesne J, Ortori CA, Barrett DA, Fromont C, Fischer PM, Harding HP, Ron D, Mallucci GR. Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity. Cell Death & Disease. 6: e1672. PMID 25741597 DOI: 10.1038/Cddis.2015.49  0.428
2015 Avezov E, Konno T, Zyryanova A, Chen W, Laine R, Crespillo-Casado A, Melo EP, Ushioda R, Nagata K, Kaminski CF, Harding HP, Ron D. Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum. Bmc Biology. 13: 2. PMID 25575667 DOI: 10.1186/S12915-014-0112-2  0.328
2015 Volmer R, Ron D. Lipid-dependent regulation of the unfolded protein response. Current Opinion in Cell Biology. 33: 67-73. PMID 25543896 DOI: 10.1016/J.Ceb.2014.12.002  0.477
2015 Preissler S, Rato C, Chen R, Antrobus R, Ding S, Fearnley IM, Ron D. Author response: AMPylation matches BiP activity to client protein load in the endoplasmic reticulum Elife. DOI: 10.7554/Elife.12621.031  0.35
2015 Parzych K, Loaiza S, Chinn TM, May P, Porsch F, Karadimitris A, Driessen C, Harding HP, Ron D, Auner HW. Abstract 1261: Comprehensive failure of intracellular protein homeostasis kills myeloma and solid cancer cells following VCP/p97 inhibition Cancer Research. 75: 1261-1261. DOI: 10.1158/1538-7445.Am2015-1261  0.431
2014 Lin Y, Pang X, Huang G, Jamison S, Fang J, Harding HP, Ron D, Lin W. Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12182-91. PMID 25186761 DOI: 10.1523/Jneurosci.1373-14.2014  0.318
2014 Tsunoda S, Avezov E, Zyryanova A, Konno T, Mendes-Silva L, Pinho Melo E, Harding HP, Ron D. Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants. Elife. 3: e03421. PMID 25073928 DOI: 10.7554/Elife.03421  0.407
2014 Le Pape S, Dimitrova E, Hannaert P, Konovalov A, Volmer R, Ron D, Thuillier R, Hauet T. Polynomial algebra reveals diverging roles of the unfolded protein response in endothelial cells during ischemia-reperfusion injury. Febs Letters. 588: 3062-7. PMID 24945730 DOI: 10.1016/J.Febslet.2014.05.065  0.356
2014 Maurin AC, Benani A, Lorsignol A, Brenachot X, Parry L, Carraro V, Guissard C, Averous J, Jousse C, Bruhat A, Chaveroux C, B'chir W, Muranishi Y, Ron D, Pénicaud L, et al. Hypothalamic eIF2α signaling regulates food intake. Cell Reports. 6: 438-44. PMID 24485657 DOI: 10.1016/J.Celrep.2014.01.006  0.346
2014 Ravindran R, Khan N, Nakaya HI, Li S, Loebbermann J, Maddur MS, Park Y, Jones DP, Chappert P, Davoust J, Weiss DS, Virgin HW, Ron D, Pulendran B. Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentation. Science (New York, N.Y.). 343: 313-7. PMID 24310610 DOI: 10.1126/Science.1246829  0.301
2014 Liu H, Huang L, Bradley J, Liu K, Bardhan K, Ron D, Mellor AL, Munn DH, McGaha TL. GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology. Molecular and Cellular Biology. 34: 428-38. PMID 24248597 DOI: 10.1128/Mcb.00946-13  0.336
2014 Chambers JE, Dalton LE, Clarke HJ, Malzer E, Dominicus CS, Patel V, Moorhead G, Ron D, Marciniak SJ. Author response: Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation Elife. DOI: 10.7554/Elife.04872.021  0.34
2014 Tsunoda S, Avezov E, Zyryanova A, Konno T, Mendes-Silva L, Melo EP, Harding HP, Ron D. Author response: Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants Elife. DOI: 10.7554/Elife.03421.013  0.396
2013 Coelho DS, Cairrão F, Zeng X, Pires E, Coelho AV, Ron D, Ryoo HD, Domingos PM. Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila. Cell Reports. 5: 791-801. PMID 24183663 DOI: 10.1016/J.Celrep.2013.09.046  0.389
2013 Araki K, Iemura S, Kamiya Y, Ron D, Kato K, Natsume T, Nagata K. Ero1-α and PDIs constitute a hierarchical electron transfer network of endoplasmic reticulum oxidoreductases. The Journal of Cell Biology. 202: 861-74. PMID 24043701 DOI: 10.1083/Jcb.201303027  0.311
2013 Tomasio SM, Harding HP, Ron D, Cross BC, Bond PJ. Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modification. Molecular Biosystems. 9: 2408-16. PMID 23884086 DOI: 10.1039/C3Mb70234K  0.414
2013 Ozasa R, Okada T, Nadanaka S, Nagamine T, Zyryanova A, Harding H, Ron D, Mori K. The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation. Cell Structure and Function. 38: 183-95. PMID 23812432 DOI: 10.1247/Csf.13012  0.376
2013 Cho JA, Lee AH, Platzer B, Cross BC, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host & Microbe. 13: 558-69. PMID 23684307 DOI: 10.1016/J.Chom.2013.03.011  0.428
2013 Avezov E, Cross BC, Kaminski Schierle GS, Winters M, Harding HP, Melo EP, Kaminski CF, Ron D. Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox. The Journal of Cell Biology. 201: 337-49. PMID 23589496 DOI: 10.1083/Jcb.201211155  0.388
2013 Lin W, Lin Y, Li J, Fenstermaker AG, Way SW, Clayton B, Jamison S, Harding HP, Ron D, Popko B. Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5980-91. PMID 23554479 DOI: 10.1523/Jneurosci.1636-12.2013  0.327
2013 D'Antonio M, Musner N, Scapin C, Ungaro D, Del Carro U, Ron D, Feltri ML, Wrabetz L. Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice. The Journal of Experimental Medicine. 210: 821-38. PMID 23547100 DOI: 10.1084/Jem.20122005  0.39
2013 Volmer R, van der Ploeg K, Ron D. Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains. Proceedings of the National Academy of Sciences of the United States of America. 110: 4628-33. PMID 23487760 DOI: 10.1073/Pnas.1217611110  0.412
2013 Tsuru A, Fujimoto N, Takahashi S, Saito M, Nakamura D, Iwano M, Iwawaki T, Kadokura H, Ron D, Kohno K. Negative feedback by IRE1β optimizes mucin production in goblet cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 2864-9. PMID 23386727 DOI: 10.1073/Pnas.1212484110  0.418
2012 Ron D, Harding HP. Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation. Cold Spring Harbor Perspectives in Biology. 4. PMID 23209157 DOI: 10.1101/Cshperspect.A013177  0.477
2012 Harding HP, Zyryanova AF, Ron D. Uncoupling proteostasis and development in vitro with a small molecule inhibitor of the pancreatic endoplasmic reticulum kinase, PERK. The Journal of Biological Chemistry. 287: 44338-44. PMID 23148209 DOI: 10.1074/Jbc.M112.428987  0.412
2012 Cross BC, Ron D. New twists in the unfolded protein response. Elife. 1: e00243. PMID 23066509 DOI: 10.7554/Elife.00243  0.366
2012 Zito E, Hansen HG, Yeo GS, Fujii J, Ron D. Endoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in mice. Molecular Cell. 48: 39-51. PMID 22981861 DOI: 10.1016/J.Molcel.2012.08.010  0.344
2012 Landau G, Ran A, Bercovich Z, Feldmesser E, Horn-Saban S, Korkotian E, Jacob-Hirsh J, Rechavi G, Ron D, Kahana C. Expression profiling and biochemical analysis suggest stress response as a potential mechanism inhibiting proliferation of polyamine-depleted cells. The Journal of Biological Chemistry. 287: 35825-37. PMID 22942278 DOI: 10.1074/Jbc.M112.381335  0.435
2012 Chambers JE, Petrova K, Tomba G, Vendruscolo M, Ron D. ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load. The Journal of Cell Biology. 198: 371-85. PMID 22869598 DOI: 10.1083/Jcb.20120200511112014C  0.438
2012 Cunha DA, Igoillo-Esteve M, Gurzov EN, Germano CM, Naamane N, Marhfour I, Fukaya M, Vanderwinden JM, Gysemans C, Mathieu C, Marselli L, Marchetti P, Harding HP, Ron D, Eizirik DL, et al. Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis. Diabetes. 61: 2763-75. PMID 22773666 DOI: 10.2337/Db12-0123  0.438
2012 Pavitt GD, Ron D. New insights into translational regulation in the endoplasmic reticulum unfolded protein response. Cold Spring Harbor Perspectives in Biology. 4. PMID 22535228 DOI: 10.1101/Cshperspect.A012278  0.478
2012 Cross BC, Bond PJ, Sadowski PG, Jha BK, Zak J, Goodman JM, Silverman RH, Neubert TA, Baxendale IR, Ron D, Harding HP. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule. Proceedings of the National Academy of Sciences of the United States of America. 109: E869-78. PMID 22315414 DOI: 10.1073/Pnas.1115623109  0.377
2011 Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science (New York, N.Y.). 334: 1081-6. PMID 22116877 DOI: 10.1126/Science.1209038  0.474
2011 Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, Larsen MJ, Burr DA, Schultz PJ, Jacobs RR, Tamayo-Castillo G, ... Ron D, et al. Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response. Journal of Biomolecular Screening. 16: 825-35. PMID 21844328 DOI: 10.1177/1087057111414893  0.358
2011 Birkenfeld AL, Lee HY, Majumdar S, Jurczak MJ, Camporez JP, Jornayvaz FR, Frederick DW, Guigni B, Kahn M, Zhang D, Weismann D, Arafat AM, Pfeiffer AF, Lieske S, Oyadomari S, ... Ron D, et al. Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism. The Journal of Biological Chemistry. 286: 36163-70. PMID 21832042 DOI: 10.1074/Jbc.M111.228817  0.347
2011 Gao N, Shang J, Huynh D, Manthati VL, Arias C, Harding HP, Kaufman RJ, Mohr I, Ron D, Falck JR, Lehrman MA. Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides. Molecular Biology of the Cell. 22: 2994-3009. PMID 21737679 DOI: 10.1091/Mbc.E11-04-0286  0.396
2011 Wang D, Zavadil J, Martin L, Parisi F, Friedman E, Levy D, Harding H, Ron D, Gardner LB. Inhibition of nonsense-mediated RNA decay by the tumor microenvironment promotes tumorigenesis. Molecular and Cellular Biology. 31: 3670-80. PMID 21730287 DOI: 10.1128/Mcb.05704-11  0.399
2011 Lin W, Lin Y, Li J, Harding HP, Ron D, Jamison S. A deregulated integrated stress response promotes interferon-γ-induced medulloblastoma. Journal of Neuroscience Research. 89: 1586-95. PMID 21688289 DOI: 10.1002/Jnr.22693  0.413
2011 Cui W, Li J, Ron D, Sha B. The structure of the PERK kinase domain suggests the mechanism for its activation. Acta Crystallographica. Section D, Biological Crystallography. 67: 423-8. PMID 21543844 DOI: 10.1107/S0907444911006445  0.407
2011 Chin KT, Kang G, Qu J, Gardner LB, Coetzee WA, Zito E, Fishman GI, Ron D. The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2583-91. PMID 21507899 DOI: 10.1096/Fj.11-184622  0.313
2011 Tsaytler P, Harding HP, Ron D, Bertolotti A. Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science (New York, N.Y.). 332: 91-4. PMID 21385720 DOI: 10.1126/Science.1201396  0.451
2011 Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nature Cell Biology. 13: 184-90. PMID 21364565 DOI: 10.1038/Ncb0311-184  0.37
2011 Ron D, Ito K. Cell biology. A translational pause to localize. Science (New York, N.Y.). 331: 543-4. PMID 21292960 DOI: 10.1126/Science.1202075  0.404
2011 Marion V, Sankaranarayanan S, de Theije C, van Dijk P, Lindsey P, Lamers MC, Harding HP, Ron D, Lamers WH, Köhler SE. Arginine deficiency causes runting in the suckling period by selectively activating the stress kinase GCN2. The Journal of Biological Chemistry. 286: 8866-74. PMID 21239484 DOI: 10.1074/Jbc.M110.216119  0.335
2010 Zito E, Melo EP, Yang Y, Wahlander Ã…, Neubert TA, Ron D. Oxidative protein folding by an endoplasmic reticulum-localized peroxiredoxin. Molecular Cell. 40: 787-97. PMID 21145486 DOI: 10.1016/J.Molcel.2010.11.010  0.349
2010 Wang H, Blais J, Ron D, Cardozo T. Structural determinants of PERK inhibitor potency and selectivity. Chemical Biology & Drug Design. 76: 480-95. PMID 21070610 DOI: 10.1111/J.1747-0285.2010.01048.X  0.342
2010 Haynes CM, Ron D. The mitochondrial UPR - protecting organelle protein homeostasis. Journal of Cell Science. 123: 3849-55. PMID 21048161 DOI: 10.1242/Jcs.075119  0.346
2010 Marcinak SJ, Ron D. The unfolded protein response in lung disease. Proceedings of the American Thoracic Society. 7: 356-62. PMID 21030513 DOI: 10.1513/pats.201001-015AW  0.349
2010 Volchuk A, Ron D. The endoplasmic reticulum stress response in the pancreatic β-cell. Diabetes, Obesity & Metabolism. 12: 48-57. PMID 21029300 DOI: 10.1111/j.1463-1326.2010.01271.x  0.325
2010 Appenzeller-Herzog C, Riemer J, Zito E, Chin KT, Ron D, Spiess M, Ellgaard L. Disulphide production by Ero1α-PDI relay is rapid and effectively regulated. The Embo Journal. 29: 3318-29. PMID 20802462 DOI: 10.1038/Emboj.2010.203  0.37
2010 Onn A, Ron D. Modeling the endoplasmic reticulum unfolded protein response. Nature Structural & Molecular Biology. 17: 924-5. PMID 20683476 DOI: 10.1038/Nsmb0810-924  0.377
2010 Ye J, Kumanova M, Hart LS, Sloane K, Zhang H, De Panis DN, Bobrovnikova-Marjon E, Diehl JA, Ron D, Koumenis C. The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation. The Embo Journal. 29: 2082-96. PMID 20473272 DOI: 10.1038/Emboj.2010.81  0.39
2010 Blais JD, Chin KT, Zito E, Zhang Y, Heldman N, Harding HP, Fass D, Thorpe C, Ron D. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. The Journal of Biological Chemistry. 285: 20993-1003. PMID 20442408 DOI: 10.1074/Jbc.M110.126599  0.367
2010 Wiseman RL, Zhang Y, Lee KP, Harding HP, Haynes CM, Price J, Sicheri F, Ron D. Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Molecular Cell. 38: 291-304. PMID 20417606 DOI: 10.1016/J.Molcel.2010.04.001  0.401
2010 Zito E, Chin KT, Blais J, Harding HP, Ron D. ERO1-beta, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis. The Journal of Cell Biology. 188: 821-32. PMID 20308425 DOI: 10.1083/Jcb.200911086  0.32
2010 Ghosh R, Lipson KL, Sargent KE, Mercurio AM, Hunt JS, Ron D, Urano F. Transcriptional regulation of VEGF-A by the unfolded protein response pathway. Plos One. 5: e9575. PMID 20221394 DOI: 10.1371/Journal.Pone.0009575  0.42
2010 Haynes CM, Yang Y, Blais SP, Neubert TA, Ron D. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Molecular Cell. 37: 529-40. PMID 20188671 DOI: 10.1016/J.Molcel.2010.01.015  0.366
2010 Tao J, Petrova K, Ron D, Sha B. Crystal structure of P58(IPK) TPR fragment reveals the mechanism for its molecular chaperone activity in UPR. Journal of Molecular Biology. 397: 1307-15. PMID 20184891 DOI: 10.1016/J.Jmb.2010.02.028  0.334
2010 Wiseman RL, Haynes CM, Ron D. SnapShot: The unfolded protein response. Cell. 140: 590-590.e2. PMID 20178750 DOI: 10.1016/J.Cell.2010.02.006  0.371
2010 Masciarelli S, Fra AM, Pengo N, Bertolotti M, Cenci S, Fagioli C, Ron D, Hendershot LM, Sitia R. CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells. Molecular Immunology. 47: 1356-65. PMID 20044139 DOI: 10.1016/J.Molimm.2009.12.003  0.436
2010 Zhao L, Rosales C, Seburn K, Ron D, Ackerman SL. Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome. Human Molecular Genetics. 19: 25-35. PMID 19801575 DOI: 10.1093/Hmg/Ddp464  0.441
2009 Woo CW, Cui D, Arellano J, Dorweiler B, Harding H, Fitzgerald KA, Ron D, Tabas I. Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling. Nature Cell Biology. 11: 1473-80. PMID 19855386 DOI: 10.1038/Ncb1996  0.416
2009 Li G, Mongillo M, Chin KT, Harding H, Ron D, Marks AR, Tabas I. Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis. The Journal of Cell Biology. 186: 783-92. PMID 19752026 DOI: 10.1083/Jcb.200904060  0.381
2009 Cobbold SP, Adams E, Farquhar CA, Nolan KF, Howie D, Lui KO, Fairchild PJ, Mellor AL, Ron D, Waldmann H. Infectious tolerance via the consumption of essential amino acids and mTOR signaling. Proceedings of the National Academy of Sciences of the United States of America. 106: 12055-60. PMID 19567830 DOI: 10.1073/Pnas.0903919106  0.312
2009 Thorp E, Li G, Seimon TA, Kuriakose G, Ron D, Tabas I. Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP. Cell Metabolism. 9: 474-81. PMID 19416717 DOI: 10.1016/J.Cmet.2009.03.003  0.316
2009 Ron D. Targeting of mRNAs to their sites of unconventional splicing in the unfolded protein response. Molecular Cell. 34: 133-4. PMID 19394288 DOI: 10.1016/J.Molcel.2009.04.003  0.32
2009 Wiseman RL, Chin KT, Haynes CM, Stanhill A, Xu CF, Roguev A, Krogan NJ, Neubert TA, Ron D. Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle. The Journal of Biological Chemistry. 284: 15233-45. PMID 19349280 DOI: 10.1074/Jbc.M109.002121  0.399
2009 Harding HP, Zhang Y, Scheuner D, Chen JJ, Kaufman RJ, Ron D. Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development. Proceedings of the National Academy of Sciences of the United States of America. 106: 1832-7. PMID 19181853 DOI: 10.1073/Pnas.0809632106  0.441
2009 Wang Q, Mora-Jensen H, Weniger MA, Perez-Galan P, Wolford C, Hai T, Ron D, Chen W, Trenkle W, Wiestner A, Ye Y. ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 2200-5. PMID 19164757 DOI: 10.1073/Pnas.0807611106  0.455
2009 Lin JH, Li H, Zhang Y, Ron D, Walter P. Divergent effects of PERK and IRE1 signaling on cell viability. Plos One. 4: e4170. PMID 19137072 DOI: 10.1371/Journal.Pone.0004170  0.402
2008 Petrova K, Oyadomari S, Hendershot LM, Ron D. Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3. The Embo Journal. 27: 2862-72. PMID 18923430 DOI: 10.1038/Emboj.2008.199  0.359
2008 Lin W, Kunkler PE, Harding HP, Ron D, Kraig RP, Popko B. Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma. The American Journal of Pathology. 173: 1508-17. PMID 18818381 DOI: 10.2353/Ajpath.2008.080449  0.398
2008 Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ. Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. The Journal of Clinical Investigation. 118: 3378-89. PMID 18776938 DOI: 10.1172/Jci34587  0.383
2008 Mak BC, Wang Q, Laschinger C, Lee W, Ron D, Harding HP, Kaufman RJ, Scheuner D, Austin RC, McCulloch CA. Novel function of PERK as a mediator of force-induced apoptosis. The Journal of Biological Chemistry. 283: 23462-72. PMID 18550523 DOI: 10.1074/Jbc.M803194200  0.315
2008 Oyadomari S, Harding HP, Zhang Y, Oyadomari M, Ron D. Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice. Cell Metabolism. 7: 520-32. PMID 18522833 DOI: 10.1016/J.Cmet.2008.04.011  0.406
2008 Yun C, Stanhill A, Yang Y, Zhang Y, Haynes CM, Xu CF, Neubert TA, Mor A, Philips MR, Ron D. Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 105: 7094-9. PMID 18467495 DOI: 10.1073/Pnas.0707025105  0.413
2008 Iqbal J, Dai K, Seimon T, Jungreis R, Oyadomari M, Kuriakose G, Ron D, Tabas I, Hussain MM. IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA. Cell Metabolism. 7: 445-55. PMID 18460335 DOI: 10.1016/J.Cmet.2008.03.005  0.365
2008 Tao J, Wu Y, Ron D, Sha B. Preliminary X-ray crystallographic studies of mouse UPR responsive protein P58(IPK) TPR fragment. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 108-10. PMID 18259061 DOI: 10.1107/S1744309108000833  0.406
2008 Pennuto M, Tinelli E, Malaguti M, Del Carro U, D'Antonio M, Ron D, Quattrini A, Feltri ML, Wrabetz L. Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice. Neuron. 57: 393-405. PMID 18255032 DOI: 10.1016/J.Neuron.2007.12.021  0.423
2008 Ron D, Hubbard SR. How IRE1 reacts to ER stress. Cell. 132: 24-6. PMID 18191217 DOI: 10.1016/J.Cell.2007.12.017  0.388
2008 Harding HP, Lackey JG, Hsu HC, Zhang Y, Deng J, Xu RM, Damha MJ, Ron D. An intact unfolded protein response in Trpt1 knockout mice reveals phylogenic divergence in pathways for RNA ligation. Rna (New York, N.Y.). 14: 225-32. PMID 18094117 DOI: 10.1261/Rna.859908  0.424
2008 Su Q, Wang S, Gao HQ, Kazemi S, Harding HP, Ron D, Koromilas AE. Modulation of the eukaryotic initiation factor 2 alpha-subunit kinase PERK by tyrosine phosphorylation. The Journal of Biological Chemistry. 283: 469-75. PMID 17998206 DOI: 10.1074/Jbc.M704612200  0.377
2007 Haynes CM, Petrova K, Benedetti C, Yang Y, Ron D. ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans. Developmental Cell. 13: 467-80. PMID 17925224 DOI: 10.1016/J.Devcel.2007.07.016  0.401
2007 Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM. Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. The American Journal of Pathology. 171: 513-24. PMID 17620365 DOI: 10.2353/Ajpath.2007.070188  0.458
2007 Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nature Reviews. Molecular Cell Biology. 8: 519-29. PMID 17565364 DOI: 10.1038/Nrm2199  0.467
2007 Shang J, Gao N, Kaufman RJ, Ron D, Harding HP, Lehrman MA. Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux. The Journal of Cell Biology. 176: 605-16. PMID 17325203 DOI: 10.1083/Jcb.200607007  0.375
2007 Lin W, Bailey SL, Ho H, Harding HP, Ron D, Miller SD, Popko B. The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage. The Journal of Clinical Investigation. 117: 448-56. PMID 17273557 DOI: 10.1172/Jci29571  0.354
2007 Ron D, Harding HP. 13 eIF2α Phosphorylation in Cellular Stress Responses and Disease Cold Spring Harbor Monograph Archive. 48: 345-368. DOI: 10.1101/087969767.48.345  0.445
2006 Blais JD, Addison CL, Edge R, Falls T, Zhao H, Wary K, Koumenis C, Harding HP, Ron D, Holcik M, Bell JC. Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress. Molecular and Cellular Biology. 26: 9517-32. PMID 17030613 DOI: 10.1128/Mcb.01145-06  0.359
2006 Marciniak SJ, Ron D. Endoplasmic reticulum stress signaling in disease. Physiological Reviews. 86: 1133-49. PMID 17015486 DOI: 10.1152/Physrev.00015.2006  0.373
2006 Stanhill A, Haynes CM, Zhang Y, Min G, Steele MC, Kalinina J, Martinez E, Pickart CM, Kong XP, Ron D. An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity. Molecular Cell. 23: 875-85. PMID 16973439 DOI: 10.1016/J.Molcel.2006.07.023  0.436
2006 Clase AC, Dimcheff DE, Favara C, Dorward D, McAtee FJ, Parrie LE, Ron D, Portis JL. Oligodendrocytes are a major target of the toxicity of spongiogenic murine retroviruses. The American Journal of Pathology. 169: 1026-38. PMID 16936275 DOI: 10.2353/Ajpath.2006.051357  0.409
2006 Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding HP, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, Ron D. Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload. Cell. 126: 727-39. PMID 16923392 DOI: 10.1016/J.Cell.2006.06.051  0.466
2006 Ron D. Cell biology. Stressed cells cope with protein overload. Science (New York, N.Y.). 313: 52-3. PMID 16825557 DOI: 10.1126/Science.1130469  0.435
2006 Benedetti C, Haynes CM, Yang Y, Harding HP, Ron D. Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response. Genetics. 174: 229-39. PMID 16816413 DOI: 10.1534/Genetics.106.061580  0.381
2006 Berlanga JJ, Ventoso I, Harding HP, Deng J, Ron D, Sonenberg N, Carrasco L, de Haro C. Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses. The Embo Journal. 25: 1730-40. PMID 16601681 DOI: 10.1038/Sj.Emboj.7601073  0.354
2006 Lin W, Kemper A, Dupree JL, Harding HP, Ron D, Popko B. Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress. Brain : a Journal of Neurology. 129: 1306-18. PMID 16504972 DOI: 10.1093/Brain/Awl044  0.329
2006 Marciniak SJ, Garcia-Bonilla L, Hu J, Harding HP, Ron D. Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK. The Journal of Cell Biology. 172: 201-9. PMID 16418533 DOI: 10.1083/Jcb.200508099  0.401
2006 Huang G, Yao J, Zeng W, Mizuno Y, Kamm KE, Stull JT, Harding HP, Ron D, Muallem S. ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice. Journal of Cell Science. 119: 153-61. PMID 16352659 DOI: 10.1242/Jcs.02731  0.379
2006 Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding H, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, Ron D. Cotranslocational Degradation Protects the Stressed Endoplasmic Reticulum from Protein Overload (DOI:10.1016/j.cell.2006.06.051) Cell. 127: 1284. DOI: 10.1016/j.cell.2006.11.027  0.307
2005 Harding HP, Zhang Y, Khersonsky S, Marciniak S, Scheuner D, Kaufman RJ, Javitt N, Chang YT, Ron D. Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression. Cell Metabolism. 2: 361-71. PMID 16330322 DOI: 10.1016/J.Cmet.2005.11.005  0.455
2005 Skalet AH, Isler JA, King LB, Harding HP, Ron D, Monroe JG. Rapid B cell receptor-induced unfolded protein response in nonsecretory B cells correlates with pro- versus antiapoptotic cell fate. The Journal of Biological Chemistry. 280: 39762-71. PMID 16188879 DOI: 10.1074/Jbc.M502640200  0.366
2005 Bi M, Naczki C, Koritzinsky M, Fels D, Blais J, Hu N, Harding H, Novoa I, Varia M, Raleigh J, Scheuner D, Kaufman RJ, Bell J, Ron D, Wouters BG, et al. ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. The Embo Journal. 24: 3470-81. PMID 16148948 DOI: 10.1038/Sj.Emboj.7600777  0.378
2005 Silva RM, Ries V, Oo TF, Yarygina O, Jackson-Lewis V, Ryu EJ, Lu PD, Marciniak SJ, Ron D, Przedborski S, Kholodilov N, Greene LA, Burke RE. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. Journal of Neurochemistry. 95: 974-86. PMID 16135078 DOI: 10.1111/J.1471-4159.2005.03428.X  0.308
2005 Costa-Mattioli M, Gobert D, Harding H, Herdy B, Azzi M, Bruno M, Bidinosti M, Ben Mamou C, Marcinkiewicz E, Yoshida M, Imataka H, Cuello AC, Seidah N, Sossin W, Lacaille JC, ... Ron D, et al. Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2. Nature. 436: 1166-73. PMID 16121183 DOI: 10.1038/Nature03897  0.311
2005 Kantor L, Harding HP, Ron D, Schiffmann R, Kaneski CR, Kimball SR, Elroy-Stein O. Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients. Human Genetics. 118: 99-106. PMID 16041584 DOI: 10.1007/S00439-005-0024-X  0.443
2005 Federovitch CM, Ron D, Hampton RY. The dynamic ER: experimental approaches and current questions. Current Opinion in Cell Biology. 17: 409-14. PMID 15975777 DOI: 10.1016/J.Ceb.2005.06.010  0.331
2005 Lin W, Harding HP, Ron D, Popko B. Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma. The Journal of Cell Biology. 169: 603-12. PMID 15911877 DOI: 10.1083/Jcb.200502086  0.407
2005 Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, Mellor AL. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity. 22: 633-42. PMID 15894280 DOI: 10.1016/J.Immuni.2005.03.013  0.34
2005 Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science (New York, N.Y.). 307: 935-9. PMID 15705855 DOI: 10.1126/Science.1101902  0.394
2004 Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, Nagata K, Harding HP, Ron D. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes & Development. 18: 3066-77. PMID 15601821 DOI: 10.1101/Gad.1250704  0.464
2004 Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N, Harding HP, Ron D. Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Molecular and Cellular Biology. 24: 10161-8. PMID 15542827 DOI: 10.1128/Mcb.24.23.10161-10168.2004  0.419
2004 Lu PD, Harding HP, Ron D. Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. The Journal of Cell Biology. 167: 27-33. PMID 15479734 DOI: 10.1083/Jcb.200408003  0.434
2004 Ron D, Hampton RY. Membrane biogenesis and the unfolded protein response. The Journal of Cell Biology. 167: 23-5. PMID 15479733 DOI: 10.1083/Jcb.200408117  0.377
2004 Ron D, Oyadomari S. Lipid phase perturbations and the unfolded protein response. Developmental Cell. 7: 287-8. PMID 15363403 DOI: 10.1016/J.Devcel.2004.08.011  0.334
2004 Blais JD, Filipenko V, Bi M, Harding HP, Ron D, Koumenis C, Wouters BG, Bell JC. Activating transcription factor 4 is translationally regulated by hypoxic stress. Molecular and Cellular Biology. 24: 7469-82. PMID 15314157 DOI: 10.1128/Mcb.24.17.7469-7482.2004  0.496
2004 Yoneda T, Benedetti C, Urano F, Clark SG, Harding HP, Ron D. Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones. Journal of Cell Science. 117: 4055-66. PMID 15280428 DOI: 10.1242/Jcs.01275  0.355
2004 Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature. 429: 841-7. PMID 15215856 DOI: 10.1038/Nature02656  0.402
2004 Hartman MG, Lu D, Kim ML, Kociba GJ, Shukri T, Buteau J, Wang X, Frankel WL, Guttridge D, Prentki M, Grey ST, Ron D, Hai T. Role for activating transcription factor 3 in stress-induced beta-cell apoptosis. Molecular and Cellular Biology. 24: 5721-32. PMID 15199129 DOI: 10.1128/Mcb.24.13.5721-5732.2004  0.388
2004 Jiang HY, Wek SA, McGrath BC, Lu D, Hai T, Harding HP, Wang X, Ron D, Cavener DR, Wek RC. Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response. Molecular and Cellular Biology. 24: 1365-77. PMID 14729979 DOI: 10.1128/Mcb.24.3.1365-1377.2004  0.469
2004 Lu PD, Jousse C, Marciniak SJ, Zhang Y, Novoa I, Scheuner D, Kaufman RJ, Ron D, Harding HP. Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2. The Embo Journal. 23: 169-79. PMID 14713949 DOI: 10.1038/Sj.Emboj.7600030  0.436
2004 Klint P, Hellman U, Wernstedt C, Aman P, Ron D, Claesson-Welsh L. Translocated in liposarcoma (TLS) is a substrate for fibroblast growth factor receptor-1. Cellular Signalling. 16: 515-20. PMID 14709340 DOI: 10.1016/J.Cellsig.2003.09.007  0.352
2003 Jousse C, Oyadomari S, Novoa I, Lu P, Zhang Y, Harding HP, Ron D. Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells. The Journal of Cell Biology. 163: 767-75. PMID 14638860 DOI: 10.1083/Jcb.200308075  0.468
2003 Feng B, Yao PM, Li Y, Devlin CM, Zhang D, Harding HP, Sweeney M, Rong JX, Kuriakose G, Fisher EA, Marks AR, Ron D, Tabas I. The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages. Nature Cell Biology. 5: 781-92. PMID 12907943 DOI: 10.1038/Ncb1035  0.316
2003 Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M, Sadri N, Yun C, Popko B, Paules R, Stojdl DF, Bell JC, Hettmann T, Leiden JM, Ron D. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Molecular Cell. 11: 619-33. PMID 12667446 DOI: 10.1016/S1097-2765(03)00105-9  0.427
2003 Novoa I, Zhang Y, Zeng H, Jungreis R, Harding HP, Ron D. Stress-induced gene expression requires programmed recovery from translational repression. The Embo Journal. 22: 1180-7. PMID 12606582 DOI: 10.1093/Emboj/Cdg112  0.454
2003 Kimball SR, Horetsky RL, Ron D, Jefferson LS, Harding HP. Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes. American Journal of Physiology. Cell Physiology. 284: C273-84. PMID 12388085 DOI: 10.1152/Ajpcell.00314.2002  0.41
2002 Ryu EJ, Harding HP, Angelastro JM, Vitolo OV, Ron D, Greene LA. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10690-8. PMID 12486162 DOI: 10.1523/Jneurosci.22-24-10690.2002  0.419
2002 Harding HP, Ron D. Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes. 51: S455-61. PMID 12475790 DOI: 10.2337/Diabetes.51.2007.S455  0.415
2002 Yan W, Frank CL, Korth MJ, Sopher BL, Novoa I, Ron D, Katze MG. Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. Proceedings of the National Academy of Sciences of the United States of America. 99: 15920-5. PMID 12446838 DOI: 10.1073/Pnas.252341799  0.481
2002 Marcu MG, Doyle M, Bertolotti A, Ron D, Hendershot L, Neckers L. Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha. Molecular and Cellular Biology. 22: 8506-13. PMID 12446770 DOI: 10.1128/Mcb.22.24.8506-8513.2002  0.432
2002 Ron D. Translational control in the endoplasmic reticulum stress response. The Journal of Clinical Investigation. 110: 1383-8. PMID 12438433 DOI: 10.1172/Jci16784  0.436
2002 Urano F, Calfon M, Yoneda T, Yun C, Kiraly M, Clark SG, Ron D. A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. The Journal of Cell Biology. 158: 639-46. PMID 12186849 DOI: 10.1083/Jcb.200203086  0.486
2002 Deng J, Harding HP, Raught B, Gingras AC, Berlanga JJ, Scheuner D, Kaufman RJ, Ron D, Sonenberg N. Activation of GCN2 in UV-irradiated cells inhibits translation. Current Biology : Cb. 12: 1279-86. PMID 12176355 DOI: 10.1016/S0960-9822(02)01037-0  0.401
2002 Harding HP, Calfon M, Urano F, Novoa I, Ron D. Transcriptional and translational control in the Mammalian unfolded protein response. Annual Review of Cell and Developmental Biology. 18: 575-99. PMID 12142265 DOI: 10.1146/Annurev.Cellbio.18.011402.160624  0.442
2002 Hori O, Ichinoda F, Tamatani T, Yamaguchi A, Sato N, Ozawa K, Kitao Y, Miyazaki M, Harding HP, Ron D, Tohyama M, M Stern D, Ogawa S. Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease. The Journal of Cell Biology. 157: 1151-60. PMID 12082077 DOI: 10.1083/Jcb.200108103  0.399
2002 Yoneda T, Urano F, Ron D. Transmission of proteotoxicity across cellular compartments. Genes & Development. 16: 1307-13. PMID 12050110 DOI: 10.1101/Gad.1000902  0.35
2002 Ron D. Proteotoxicity in the endoplasmic reticulum: lessons from the Akita diabetic mouse. The Journal of Clinical Investigation. 109: 443-5. PMID 11854314 DOI: 10.1172/Jci15020  0.361
2002 Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, Clark SG, Ron D. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature. 415: 92-6. PMID 11780124 DOI: 10.1038/415092A  0.436
2001 Harding HP, Novoa I, Bertolotti A, Zeng H, Zhang Y, Urano F, Jousse C, Ron D. Translational regulation in the cellular response to biosynthetic load on the endoplasmic reticulum. Cold Spring Harbor Symposia On Quantitative Biology. 66: 499-508. PMID 12762052 DOI: 10.1101/Sqb.2001.66.499  0.325
2001 Jousse C, Bruhat A, Carraro V, Urano F, Ferrara M, Ron D, Fafournoux P. Inhibition of CHOP translation by a peptide encoded by an open reading frame localized in the chop 5'UTR. Nucleic Acids Research. 29: 4341-51. PMID 11691921 DOI: 10.1093/Nar/29.21.4341  0.434
2001 Sok J, Calfon M, Lu J, Lichtlen P, Clark SG, Ron D. Arsenite-inducible RNA-associated protein (AIRAP) protects cells from arsenite toxicity. Cell Stress & Chaperones. 6: 6-15. PMID 11525245 DOI: 10.1379/1466-1268(2001)006<0006:Airapa>2.0.Co;2  0.403
2001 Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, Ron D. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Molecular Cell. 7: 1153-63. PMID 11430819 DOI: 10.1016/S1097-2765(01)00264-7  0.453
2001 Kumar R, Azam S, Sullivan JM, Owen C, Cavener DR, Zhang P, Ron D, Harding HP, Chen JJ, Han A, White BC, Krause GS, DeGracia DJ. Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK. Journal of Neurochemistry. 77: 1418-21. PMID 11389192 DOI: 10.1046/J.1471-4159.2001.00387.X  0.318
2001 Novoa I, Zeng H, Harding HP, Ron D. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. The Journal of Cell Biology. 153: 1011-22. PMID 11381086 DOI: 10.1083/Jcb.153.5.1011  0.487
2001 Ron D. Hyperhomocysteinemia and function of the endoplasmic reticulum. The Journal of Clinical Investigation. 107: 1221-2. PMID 11375410 DOI: 10.1172/Jci13092  0.501
2001 Bertolotti A, Wang X, Novoa I, Jungreis R, Schlessinger K, Cho JH, West AB, Ron D. Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. The Journal of Clinical Investigation. 107: 585-93. PMID 11238559 DOI: 10.1172/Jci11476  0.397
2000 Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression. Nature Cell Biology. 2: 863-70. PMID 11146649 DOI: 10.1038/35046500  0.444
2000 Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, Ron D. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Molecular Cell. 6: 1099-108. PMID 11106749 DOI: 10.1016/S1097-2765(00)00108-8  0.475
2000 Urano F, Bertolotti A, Ron D. IRE1 and efferent signaling from the endoplasmic reticulum. Journal of Cell Science. 113: 3697-702. PMID 11034898  0.396
2000 Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Molecular Cell. 5: 897-904. PMID 10882126 DOI: 10.1016/S1097-2765(00)80330-5  0.483
2000 Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nature Cell Biology. 2: 326-32. PMID 10854322 DOI: 10.1038/35014014  0.465
2000 Kuroda M, Sok J, Webb L, Baechtold H, Urano F, Yin Y, Chung P, de Rooij DG, Akhmedov A, Ashley T, Ron D. Male sterility and enhanced radiation sensitivity in TLS(-/-) mice. The Embo Journal. 19: 453-62. PMID 10654943 DOI: 10.1093/Emboj/19.3.453  0.326
2000 Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP, Ron D. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science (New York, N.Y.). 287: 664-6. PMID 10650002 DOI: 10.1126/Science.287.5453.664  0.453
2000 Ron D, Harding HP. 15 PERK and Translational Control by Stress in the Endoplasmic Reticulum Cold Spring Harbor Monograph Archive. 39: 547-560. DOI: 10.1101/087969618.39.547  0.449
1999 Maytin EV, Lin JC, Krishnamurthy R, Batchvarova N, Ron D, Mitchell PJ, Habener JF. Keratin 10 gene expression during differentiation of mouse epidermis requires transcription factors C/EBP and AP-2. Developmental Biology. 216: 164-81. PMID 10588870 DOI: 10.1006/Dbio.1999.9460  0.52
1999 Wang XZ, Jolicoeur EM, Conte N, Chaffanet M, Zhang Y, Mozziconacci MJ, Feiner H, Birnbaum D, Pébusque MJ, Ron D. gamma-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line. Oncogene. 18: 5718-21. PMID 10523851 DOI: 10.1038/Sj.Onc.1202950  0.317
1999 Kuroda M, Wang X, Sok J, Yin Y, Chung P, Giannotti JW, Jacobs KA, Fitz LJ, Murtha-Riel P, Turner KJ, Ron D. Induction of a secreted protein by the myxoid liposarcoma oncogene. Proceedings of the National Academy of Sciences of the United States of America. 96: 5025-30. PMID 10220412 DOI: 10.1073/Pnas.96.9.5025  0.441
1999 Jousse C, Bruhat A, Harding HP, Ferrara M, Ron D, Fafournoux P. Amino acid limitation regulates CHOP expression through a specific pathway independent of the unfolded protein response. Febs Letters. 448: 211-6. PMID 10218478 DOI: 10.1016/S0014-5793(99)00373-7  0.397
1999 Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature. 397: 271-4. PMID 9930704 DOI: 10.1038/16729  0.468
1999 Sok J, Wang XZ, Batchvarova N, Kuroda M, Harding H, Ron D. CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI. Molecular and Cellular Biology. 19: 495-504. PMID 9858573 DOI: 10.1128/Mcb.19.1.495  0.41
1998 Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M, Ron D. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. The Embo Journal. 17: 5708-17. PMID 9755171 DOI: 10.1093/Emboj/17.19.5708  0.468
1998 Wang XZ, Kuroda M, Sok J, Batchvarova N, Kimmel R, Chung P, Zinszner H, Ron D. Identification of novel stress-induced genes downstream of chop. The Embo Journal. 17: 3619-30. PMID 9649432 DOI: 10.1093/Emboj/17.13.3619  0.486
1998 Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL, Ron D. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes & Development. 12: 982-95. PMID 9531536 DOI: 10.1101/Gad.12.7.982  0.404
1998 Powers CA, Mathur M, Raaka BM, Ron D, Samuels HH. TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors. Molecular Endocrinology (Baltimore, Md.). 12: 4-18. PMID 9440806 DOI: 10.1210/Mend.12.1.0043  0.331
1997 Bruhat A, Jousse C, Wang XZ, Ron D, Ferrara M, Fafournoux P. Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels. The Journal of Biological Chemistry. 272: 17588-93. PMID 9211906 DOI: 10.1074/Jbc.272.28.17588  0.434
1997 Zinszner H, Immanuel D, Yin Y, Liang F, Ron D. A topogenic role for the oncogenic N-terminus of TLS: nucleolar localization when transcription is inhibited. Oncogene. 14: 451-461. PMID 9053842 DOI: 10.1038/Sj.Onc.1200854  0.372
1996 Wang XZ, Lawson B, Brewer JW, Zinszner H, Sanjay A, Mi LJ, Boorstein R, Kreibich G, Hendershot LM, Ron D. Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Molecular and Cellular Biology. 16: 4273-80. PMID 8754828 DOI: 10.1128/Mcb.16.8.4273  0.431
1996 Ubeda M, Wang XZ, Zinszner H, Wu I, Habener JF, Ron D. Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element. Molecular and Cellular Biology. 16: 1479-89. PMID 8657121 DOI: 10.1128/Mcb.16.4.1479  0.607
1996 Wang XZ, Ron D. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science (New York, N.Y.). 272: 1347-9. PMID 8650547 DOI: 10.1126/Science.272.5266.1347  0.392
1995 Immanuel D, Zinszner H, Ron D. Association of SARFH (sarcoma-associated RNA-binding fly homolog) with regions of chromatin transcribed by RNA polymerase II. Molecular and Cellular Biology. 15: 4562-4571. PMID 7623847 DOI: 10.1128/Mcb.15.8.4562  0.345
1995 Batchvarova N, Wang XZ, Ron D. Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). The Embo Journal. 14: 4654-4661. DOI: 10.1002/J.1460-2075.1995.Tb00147.X  0.401
1994 Zhan Q, Lord KA, Alamo I, Hollander MC, Carrier F, Ron D, Kohn KW, Hoffman B, Liebermann DA, Fornace AJ. The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Molecular and Cellular Biology. 14: 2361-71. PMID 8139541 DOI: 10.1128/Mcb.14.4.2361  0.356
1994 Barone MV, Crozat A, Tabaee A, Philipson L, Ron D. CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes & Development. 8: 453-64. PMID 8125258 DOI: 10.1101/Gad.8.4.453  0.435
1994 Zinszner H, Albalat R, Ron D. A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP. Genes & Development. 8: 2513-26. PMID 7958914 DOI: 10.1101/Gad.8.21.2513  0.657
1994 Panagopoulos I, Åman P, Ron D, Höglund M, Mandahl N, Mitelman F. Two variants of the TLS-CHOP fusion transcript in myxoid liposarcomas with the 12;16 translocation Cancer Genetics and Cytogenetics. 77: 177. DOI: 10.1016/0165-4608(94)90343-3  0.309
1993 Crozat A, Åman P, Mandahl N, Ron D. Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Nature. 363: 640-644. PMID 8510758 DOI: 10.1038/363640A0  0.379
1993 Vallejo M, Ron D, Miller CP, Habener JF. C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements. Proceedings of the National Academy of Sciences of the United States of America. 90: 4679-83. PMID 8506317 DOI: 10.1073/Pnas.90.10.4679  0.549
1993 McGehee RE, Ron D, Brasier AR, Habener JF. Differentiation-specific element: a cis-acting developmental switch required for the sustained transcriptional expression of the angiotensinogen gene during hormonal-induced differentiation of 3T3-L1 fibroblasts to adipocytes. Molecular Endocrinology (Baltimore, Md.). 7: 551-60. PMID 7684818 DOI: 10.1210/Mend.7.4.7684818  0.541
1993 Brasier AR, Ron D. Luciferase reporter gene assay in mammalian cells. Methods in Enzymology. 216: 386-97. PMID 1336098 DOI: 10.1016/0076-6879(92)16036-J  0.368
1992 Ron D, Brasier AR, McGehee RE, Habener JF. Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/enhancer binding protein (C/EBP). The Journal of Clinical Investigation. 89: 223-33. PMID 1729273 DOI: 10.1172/Jci115566  0.586
1992 Ron D, Habener JF. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes & Development. 6: 439-53. PMID 1547942 DOI: 10.1101/Gad.6.3.439  0.595
1991 Ron D, Brasier AR, Habener JF. Angiotensinogen gene-inducible enhancer-binding protein 1, a member of a new family of large nuclear proteins that recognize nuclear factor kappa B-binding sites through a zinc finger motif. Molecular and Cellular Biology. 11: 2887-95. PMID 2017183 DOI: 10.1128/Mcb.11.5.2887  0.586
1991 Brasier AR, Ron D. Use of Firefly Luciferase Reporter Gene to Study Angiotensinogen Acute Phase Response Element Methods in Neurosciences. 5: 108-123. DOI: 10.1016/B978-0-12-185259-7.50012-0  0.344
1990 Ron D, Brasier AR, Wright KA, Habener JF. The permissive role of glucocorticoids on interleukin-1 stimulation of angiotensinogen gene transcription is mediated by an interaction between inducible enhancers. Molecular and Cellular Biology. 10: 4389-95. PMID 2370871 DOI: 10.1128/mcb.10.8.4389-4395.1990  0.549
1990 Brasier AR, Ron D, Tate JE, Habener JF. A family of constitutive C/EBP-like DNA binding proteins attenuate the IL-1 alpha induced, NF kappa B mediated trans-activation of the angiotensinogen gene acute-phase response element. The Embo Journal. 9: 3933-44. PMID 2174352 DOI: 10.1002/J.1460-2075.1990.Tb07614.X  0.574
1990 Ron D, Brasier AR, Habener JF. Transcriptional regulation of hepatic angiotensinogen gene expression by the acute-phase response. Molecular and Cellular Endocrinology. 74: C97-104. PMID 2128877 DOI: 10.1016/0303-7207(90)90221-S  0.569
1990 Ron D, Brasier AR, Wright KA, Tate JE, Habener JF. An inducible 50-kilodalton NF kappa B-like protein and a constitutive protein both bind the acute-phase response element of the angiotensinogen gene. Molecular and Cellular Biology. 10: 1023-32. PMID 2106065 DOI: 10.1128/Mcb.10.3.1023  0.573
1990 Brasier AR, Ron D, Tate JE, Habener JF. Synergistic enhansons located within an acute phase responsive enhancer modulate glucocorticoid induction of angiotensinogen gene transcription. Molecular Endocrinology (Baltimore, Md.). 4: 1921-33. PMID 1707127 DOI: 10.1210/Mend-4-12-1921  0.588
1989 Brasier AR, Tate JE, Ron D, Habener JF. Multiple cis-acting DNA regulatory elements mediate hepatic angiotensinogen gene expression. Molecular Endocrinology (Baltimore, Md.). 3: 1022-34. PMID 2544800 DOI: 10.1210/Mend-3-6-1022  0.54
Low-probability matches (unlikely to be authored by this person)
2014 Lin Y, Huang G, Jamison S, Li J, Harding HP, Ron D, Lin W. PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases. The American Journal of Pathology. 184: 507-19. PMID 24269558 DOI: 10.1016/J.Ajpath.2013.10.009  0.298
2017 Aprile FA, Källstig E, Limorenko G, Vendruscolo M, Ron D, Hansen C. The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation. Scientific Reports. 7: 9039. PMID 28831037 DOI: 10.1038/S41598-017-08324-Z  0.298
2005 Maurin AC, Jousse C, Averous J, Parry L, Bruhat A, Cherasse Y, Zeng H, Zhang Y, Harding HP, Ron D, Fafournoux P. The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores. Cell Metabolism. 1: 273-7. PMID 16054071 DOI: 10.1016/J.Cmet.2005.03.004  0.297
2015 Nobre L, Wise D, Ron D, Volmer R. Modulation of Innate Immune Signalling by Lipid-Mediated MAVS Transmembrane Domain Oligomerization. Plos One. 10: e0136883. PMID 26317833 DOI: 10.1371/Journal.Pone.0136883  0.295
1996 Åman P, Panagopoulos I, Lassen C, Fioretos T, Mencinger M, Toresson H, Höglund M, Forster A, Rabbitts TH, Ron D, Mandahl N, Mitelman F. Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUS Genomics. 37: 1-8. PMID 8921363 DOI: 10.1006/Geno.1996.0513  0.295
2006 Pereira RC, Stadmeyer L, Marciniak SJ, Ron D, Canalis E. C/EBP homologous protein is necessary for normal osteoblastic function. Journal of Cellular Biochemistry. 97: 633-40. PMID 16220546 DOI: 10.1002/Jcb.20660  0.295
2019 Amin-Wetzel N, Neidhardt L, Yan Y, Mayer MP, Ron D. Author response: Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR Elife. DOI: 10.7554/Elife.50793.Sa2  0.295
1999 Kanoe H, Nakayama T, Hosaka T, Murakami H, Yamamoto H, Nakashima Y, Tsuboyama T, Nakamura T, Ron D, Sasaki MS, Toguchida J. Characteristics of genomic breakpoints in TLS-CHOP translocations in liposarcomas suggest the involvement of Translin and topoisomerase II in the process of translocation. Oncogene. 18: 721-9. PMID 9989822 DOI: 10.1038/Sj.Onc.1202364  0.295
2006 Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metabolism. 4: 441-51. PMID 17141628 DOI: 10.1016/J.Cmet.2006.10.010  0.295
2011 Adams DR, Ron D, Kiely PA. RACK1, A multifaceted scaffolding protein: Structure and function. Cell Communication and Signaling : Ccs. 9: 22. PMID 21978545 DOI: 10.1186/1478-811X-9-22  0.294
2019 Harding HP, Ordonez A, Allen F, Parts L, Inglis AJ, Williams RL, Ron D. Author response: The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells Elife. DOI: 10.7554/Elife.50149.Sa2  0.292
2021 Marciniak SJ, Chambers JE, Ron D. Pharmacological targeting of endoplasmic reticulum stress in disease. Nature Reviews. Drug Discovery. PMID 34702991 DOI: 10.1038/s41573-021-00320-3  0.291
2015 Chen W, Avezov E, Schlachter SC, Gielen F, Laine RF, Harding HP, Hollfelder F, Ron D, Kaminski CF. A method to quantify FRET stoichiometry with phasor plot analysis and acceptor lifetime ingrowth. Biophysical Journal. 108: 999-1002. PMID 25762312 DOI: 10.1016/J.Bpj.2015.01.012  0.289
2017 Crespillo-Casado A, Chambers JE, Fischer PM, Marciniak SJ, Ron D. Author response: PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz Elife. DOI: 10.7554/Elife.26109.021  0.284
2013 Martino MB, Jones L, Brighton B, Ehre C, Abdulah L, Davis CW, Ron D, O'Neal WK, Ribeiro CM. The ER stress transducer IRE1β is required for airway epithelial mucin production. Mucosal Immunology. 6: 639-54. PMID 23168839 DOI: 10.1038/mi.2012.105  0.28
2015 Preissler S, Chambers JE, Crespillo-Casado A, Avezov E, Miranda E, Perez J, Hendershot LM, Harding HP, Ron D. Author response: Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker Elife. DOI: 10.7554/Elife.08961.028  0.28
2000 Adélaïde J, Chaffanet M, Mozziconacci MJ, Popovici C, Conte N, Fernandez F, Sobol H, Jacquemier J, Pébusque M, Ron D, Lafage-Pochitaloff M, Birnbaum D. Translocation and coamplification of loci from chromosome arms 8p and 11q in the MDA-MB-175 mammary carcinoma cell line. International Journal of Oncology. 16: 683-8. PMID 10717235 DOI: 10.3892/Ijo.16.4.683  0.279
2006 Ron D, Hinnebusch AG. Targeting translation in hypoxic tumors. Acs Chemical Biology. 1: 145-8. PMID 17163661 DOI: 10.1021/Cb600125Y  0.278
2008 Grosso S, Volta V, Sala LA, Vietri M, Marchisio PC, Ron D, Biffo S. PKCbetaII modulates translation independently from mTOR and through RACK1. The Biochemical Journal. 415: 77-85. PMID 18557705 DOI: 10.1042/BJ20080463  0.277
2013 Gulati P, Cheung MK, Antrobus R, Church CD, Harding HP, Tung YC, Rimmington D, Ma M, Ron D, Lehner PJ, Ashcroft FM, Cox RD, Coll AP, O'Rahilly S, Yeo GS. Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proceedings of the National Academy of Sciences of the United States of America. 110: 2557-62. PMID 23359686 DOI: 10.1073/Pnas.1222796110  0.276
1992 Åman P, Ron D, Mandahl N, Fioretos T, Heim S, Arheden K, Willén H, Rydholm A, Mitelman F. Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11). Genes, Chromosomes and Cancer. 5: 278-285. PMID 1283316 DOI: 10.1002/Gcc.2870050403  0.275
2013 Massie C, Baxter EJ, Nice FL, Gundem G, Wedge D, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, Godfrey AL, Hinton J, Martincorena I, Loo PV, Jones AV, ... ... Ron D, et al. The Genomic Landscape of Myeloproliferative Neoplasms: Somatic Calr Mutations in the Majority of JAK2-Wildtype Patients Blood. 122. DOI: 10.1182/Blood.V122.21.Lba-2.Lba-2  0.271
1999 Baechtold H, Kuroda M, Sok J, Ron D, Lopez BS, Akhmedov AT. Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation. The Journal of Biological Chemistry. 274: 34337-42. PMID 10567410 DOI: 10.1074/Jbc.274.48.34337  0.27
2012 Maurin AC, Chaveroux C, Lambert-Langlais S, Carraro V, Jousse C, Bruhat A, Averous J, Parry L, Ron D, Alliot J, Fafournoux P. The amino acid sensor GCN2 biases macronutrient selection during aging. European Journal of Nutrition. 51: 119-26. PMID 21614613 DOI: 10.1007/S00394-011-0205-4  0.266
2020 Zyryanova AF, Kashiwagi K, Rato C, Harding HP, Crespillo-Casado A, Perera LA, Sakamoto A, Nishimoto M, Yonemochi M, Shirouzu M, Ito T, Ron D. ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B. Molecular Cell. PMID 33220178 DOI: 10.1016/j.molcel.2020.10.031  0.265
2014 Chen R, Rato C, Yan Y, Crespillo-Casado A, Clarke HJ, Harding HP, Marciniak SJ, Read RJ, Ron D. Author response: G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases Elife. DOI: 10.7554/Elife.04871.028  0.263
2012 Neasta J, Kiely PA, He DY, Adams DR, O'Connor R, Ron D. Direct interaction between scaffolding proteins RACK1 and 14-3-3ζ regulates brain-derived neurotrophic factor (BDNF) transcription. The Journal of Biological Chemistry. 287: 322-36. PMID 22069327 DOI: 10.1074/jbc.M111.272195  0.26
2004 Preger E, Ziv I, Shabtay A, Sher I, Tsang M, Dawid IB, Altuvia Y, Ron D. Alternative splicing generates an isoform of the human Sef gene with altered subcellular localization and specificity. Proceedings of the National Academy of Sciences of the United States of America. 101: 1229-34. PMID 14742870 DOI: 10.1073/Pnas.0307952100  0.258
2005 Rubin C, Zwang Y, Vaisman N, Ron D, Yarden Y. Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways. The Journal of Biological Chemistry. 280: 9735-44. PMID 15637081 DOI: 10.1074/Jbc.M408308200  0.257
2012 Ma M, Harding HP, O'Rahilly S, Ron D, Yeo GS. Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate. The Biochemical Journal. 444: 183-7. PMID 22435707 DOI: 10.1042/Bj20120065  0.257
2017 Preissler S, Rohland L, Yan Y, Chen R, Read RJ, Ron D. Author response: AMPylation targets the rate-limiting step of BiP’s ATPase cycle for its functional inactivation Elife. DOI: 10.7554/Elife.29428.039  0.256
2012 Iqbal J, Queiroz J, Li Y, Jiang XC, Ron D, Hussain MM. Increased intestinal lipid absorption caused by Ire1β deficiency contributes to hyperlipidemia and atherosclerosis in apolipoprotein E-deficient mice. Circulation Research. 110: 1575-84. PMID 22556338 DOI: 10.1161/Circresaha.112.264283  0.255
2010 He DY, Neasta J, Ron D. Epigenetic regulation of BDNF expression via the scaffolding protein RACK1. The Journal of Biological Chemistry. 285: 19043-50. PMID 20410295 DOI: 10.1074/jbc.M110.100693  0.253
2013 Ron D, Adams DR, Baillie GS, Long A, O'Connor R, Kiely PA. RACK1 to the future--a historical perspective. Cell Communication and Signaling : Ccs. 11: 53. PMID 23915285 DOI: 10.1186/1478-811X-11-53  0.253
2013 Ahmadiantehrani S, Ron D. Dopamine D2 receptor activation leads to an up-regulation of glial cell line-derived neurotrophic factor via Gβγ-Erk1/2-dependent induction of Zif268. Journal of Neurochemistry. 125: 193-204. PMID 23373701 DOI: 10.1111/Jnc.12178  0.252
2013 Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, Godfrey AL, Hinton J, Martincorena I, Van Loo P, ... ... Ron D, et al. Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. The New England Journal of Medicine. 369: 2391-405. PMID 24325359 DOI: 10.1056/Nejmoa1312542  0.252
2018 Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. Cell Host & Microbe. 23: 571. PMID 29649448 DOI: 10.1016/j.chom.2018.03.005  0.252
2002 He DY, Vagts AJ, Yaka R, Ron D. Ethanol induces gene expression via nuclear compartmentalization of receptor for activated C kinase 1. Molecular Pharmacology. 62: 272-80. PMID 12130678 DOI: 10.1124/mol.62.2.272  0.25
1999 Ron D, Kazanietz MG. New insights into the regulation of protein kinase C and novel phorbol ester receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 1658-76. PMID 10506570 DOI: 10.1096/Fasebj.13.13.1658  0.25
2001 Bertolotti A, Ron D. Alterations in an IRE1-RNA complex in the mammalian unfolded protein response. Journal of Cell Science. 114: 3207-12. PMID 11590247  0.249
2001 Ma Y, Lu Y, Zeng H, Ron D, Mo W, Neubert TA. Characterization of phosphopeptides from protein digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nanoelectrospray quadrupole time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 15: 1693-700. PMID 11555868 DOI: 10.1002/Rcm.426  0.249
2006 Kiely PA, O'Gorman D, Luong K, Ron D, O'Connor R. Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and beta1 integrin to promote cell migration. Molecular and Cellular Biology. 26: 4041-51. PMID 16705158 DOI: 10.1128/MCB.01868-05  0.248
1989 Ron D, Powers AC, Pandian MR, Godine JE, Axelrod L. Increased insulin-like growth factor II production and consequent suppression of growth hormone secretion: a dual mechanism for tumor-induced hypoglycemia. The Journal of Clinical Endocrinology and Metabolism. 68: 701-6. PMID 2646313 DOI: 10.1210/Jcem-68-4-701  0.241
2012 Cho JA, Lee A, Plazer B, Harding HP, Ron D, Fiebiger E, Glimcher L, Kagan JC, Lencer WI. 1111 Innate Immune Sensing of a Bacterial Protein in the Endoplasmic Reticulum by Inositol-Requiring Enzyme 1 (Ire1α) Gastroenterology. 142: S-201. DOI: 10.1016/S0016-5085(12)60754-9  0.24
2019 Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross J, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, ... ... Ron D, et al. GDF15 mediates the effects of metformin on body weight and energy balance. Nature. PMID 31875646 DOI: 10.1038/S41586-019-1911-Y  0.239
2006 Ziv I, Fuchs Y, Preger E, Shabtay A, Harduf H, Zilpa T, Dym N, Ron D. The human sef-a isoform utilizes different mechanisms to regulate receptor tyrosine kinase signaling pathways and subsequent cell fate. The Journal of Biological Chemistry. 281: 39225-35. PMID 17035228 DOI: 10.1074/jbc.M607327200  0.238
2002 Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, Clark SG, Ron D. corrigendum: IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA Nature. 420: 202-202. DOI: 10.1038/Nature01193  0.236
1994 Ron D. Inducible growth arrest: new mechanistic insights. Proceedings of the National Academy of Sciences of the United States of America. 91: 1985-6. PMID 8134335 DOI: 10.1073/Pnas.91.6.1985  0.236
1998 Miralles F, Ron D, Baiget M, Félez J, Muñoz-Cánoves P. Differential regulation of urokinase-type plasminogen activator expression by basic fibroblast growth factor and serum in myogenesis. Requirement of a common mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 273: 2052-8. PMID 9442043 DOI: 10.1074/jbc.273.4.2052  0.235
2023 Perera LA, Hattersley AT, Harding HP, Wakeling MN, Flanagan SE, Mohsina I, Raza J, Gardham A, Ron D, De Franco E. Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP. Embo Molecular Medicine. e16491. PMID 36704923 DOI: 10.15252/emmm.202216491  0.235
2010 Zito E, Chin KT, Blais J, Harding HP, Ron D. ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis (The Journal of Cell Biology (2010) 188, 6 (821-832)) Journal of Cell Biology. 189: 769. DOI: 10.1083/Jcb.20091108620100423C  0.234
1988 Axelrod L, Ron D. Insulin-like growth factor II and the riddle of tumor-induced hypoglycemia. The New England Journal of Medicine. 319: 1477-1479. PMID 3185665 DOI: 10.1056/Nejm198812013192209  0.228
2018 Aprile FA, Källstig E, Limorenko G, Vendruscolo M, Ron D, Hansen C. Author Correction: The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation. Scientific Reports. 8: 11848. PMID 30068912 DOI: 10.1038/S41598-018-29893-7  0.228
1997 Ron D. New developments in the molecular genetics of cancer: AACR Meeting Disrupted Transcription Factors in Cancer, San Diego, CA, USA, 17–21 January 1997 Trends in Genetics. 13: 136-137. DOI: 10.1016/S0168-9525(97)01100-1  0.226
1999 Ron D, Jiang Z, Yao L, Vagts A, Diamond I, Gordon A. Coordinated movement of RACK1 with activated betaIIPKC. The Journal of Biological Chemistry. 274: 27039-46. PMID 10480917 DOI: 10.1074/Jbc.274.38.27039  0.224
2004 Thornton C, Tang KC, Phamluong K, Luong K, Vagts A, Nikanjam D, Yaka R, Ron D. Spatial and temporal regulation of RACK1 function and N-methyl-D-aspartate receptor activity through WD40 motif-mediated dimerization. The Journal of Biological Chemistry. 279: 31357-64. PMID 15140893 DOI: 10.1074/jbc.M402316200  0.22
2021 Yan Y, Harding HP, Ron D. Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nature Structural & Molecular Biology. 28: 835-846. PMID 34625748 DOI: 10.1038/s41594-021-00666-7  0.218
1999 Harding HP, Zhang Y, Ron D. Erratum: Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase Nature. 398: 90-90. DOI: 10.1038/18057  0.218
2021 Perera LA, Preissler S, Zaccai NR, Prévost S, Devos JM, Haertlein M, Ron D. Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD. Nature Communications. 12: 5004. PMID 34408154 DOI: 10.1038/s41467-021-25076-7  0.214
2012 Zak J, Ron D, Riva E, Harding HP, Cross BC, Baxendale IR. Establishing a flow process to coumarin-8-carbaldehydes as important synthetic scaffolds. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 9901-10. PMID 22782929 DOI: 10.1002/Chem.201201039  0.209
1983 Ron D, Oren I, Aviram M, Better OS, Brook JG. Accumulation of lipoprotein remnants in patients with chronic renal failure. Atherosclerosis. 46: 67-75. PMID 6838695 DOI: 10.1016/0021-9150(83)90165-X  0.208
2003 Ungless MA, Singh V, Crowder TL, Yaka R, Ron D, Bonci A. Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons. Neuron. 39: 401-7. PMID 12895416 DOI: 10.1016/S0896-6273(03)00461-6  0.205
2005 West DC, Rees CG, Duchesne L, Patey SJ, Terry CJ, Turnbull JE, Delehedde M, Heegaard CW, Allain F, Vanpouille C, Ron D, Fernig DG. Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. The Journal of Biological Chemistry. 280: 13457-64. PMID 15695515 DOI: 10.1074/Jbc.M410924200  0.203
1999 Ron D, Napolitano EW, Voronova A, Vasquez NJ, Roberts DN, Calio BL, Caothien RH, Pettiford SM, Wellik S, Mandac JB, Kauvar LM. Direct interaction in T-cells between thetaPKC and the tyrosine kinase p59fyn. The Journal of Biological Chemistry. 274: 19003-10. PMID 10383400 DOI: 10.1074/jbc.274.27.19003  0.202
2020 Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, ... ... Ron D, et al. Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance. Nature. PMID 32051582 DOI: 10.1038/S41586-020-2031-4  0.202
1983 Ron D, Aviram M, Brook JG. High density lipoprotein in octogenarians Biochemical Medicine. 30: 253-260. PMID 6651792 DOI: 10.1016/0006-2944(83)90091-1  0.2
2012 Fuchs Y, Brunwasser M, Haif S, Haddad J, Shneyer B, Goldshmidt-Tran O, Korsensky L, Abed M, Zisman-Rozen S, Koren L, Carmi Y, Apte R, Yang RB, Orian A, Bejar J, ... Ron D, et al. Sef is an inhibitor of proinflammatory cytokine signaling, acting by cytoplasmic sequestration of NF-κB. Developmental Cell. 23: 611-23. PMID 22975329 DOI: 10.1016/j.devcel.2012.07.013  0.199
2008 Jurd R, Thornton C, Wang J, Luong K, Phamluong K, Kharazia V, Gibb SL, Ron D. Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner. The Journal of Biological Chemistry. 283: 301-10. PMID 17962190 DOI: 10.1074/jbc.M705580200  0.199
2023 Marszalek J, De Los Rios P, Cyr D, Mayer MP, Adupa V, Andréasson C, Blatch GL, Braun JEA, Brodsky JL, Bukau B, Chapple JP, Conz C, Dementin S, Genevaux P, Genest O, ... ... Ron D, et al. J-domain proteins: From molecular mechanisms to diseases. Cell Stress & Chaperones. 29: 21-33. PMID 38320449 DOI: 10.1016/j.cstres.2023.12.002  0.198
1984 Ron D, Taitelman U, Michaelson M, Bar-Joseph G, Bursztein S, Better OS. Prevention of Acute Renal Failure in Traumatic Rhabdomyolysis Jama Internal Medicine. 144: 277-280. DOI: 10.1001/Archinte.1984.00350140077012  0.196
1999 Rodriguez MM, Ron D, Touhara K, Chen CH, Mochly-Rosen D. RACK1, a protein kinase C anchoring protein, coordinates the binding of activated protein kinase C and select pleckstrin homology domains in vitro. Biochemistry. 38: 13787-94. PMID 10529223 DOI: 10.1021/Bi991055K  0.194
2006 Ashique AM, Kharazia V, Yaka R, Phamluong K, Peterson AS, Ron D. Localization of the scaffolding protein RACK1 in the developing and adult mouse brain. Brain Research. 1069: 31-8. PMID 16414032 DOI: 10.1016/J.Brainres.2005.11.018  0.193
1997 Zinszner H, Sok J, Immanuel D, Yin Y, Ron D. TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling. Journal of Cell Science. 110: 1741-50. PMID 9264461  0.19
2011 Barak S, Ahmadiantehrani S, Kharazia V, Ron D. Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption. Translational Psychiatry. 1. PMID 22238721 DOI: 10.1038/Tp.2011.57  0.188
2022 Sekine Y, Ron D, Zyryanova AF. Fluorescence Intensity-Based eIF2B's Guanine Nucleotide-Exchange Factor Activity Assay. Methods in Molecular Biology (Clifton, N.J.). 2428: 187-196. PMID 35171481 DOI: 10.1007/978-1-0716-1975-9_12  0.187
2005 Maurin AC, Jousse C, Balage M, Averous J, Parry L, Bruhat A, Cherasse Y, Zeng H, Zhang Y, Harding H, Ron D, Fafournoux P. [GCN2 regulates feeding behavior to maintain amino acid homeostasis in omnivores]. Mã©Decine Sciences : M/S. 21: 799-801. PMID 16197891 DOI: 10.1051/Medsci/20052110799  0.187
2014 Lutwak E, Price CA, Abramovich SS, Rabinovitz S, Granot I, Dekel N, Ron D. Expression and regulation of the tumor suppressor, SEF, during folliculogenesis in humans and mice. Reproduction (Cambridge, England). 148: 507-17. PMID 25118304 DOI: 10.1530/Rep-14-0070  0.185
1995 Mochly-Rosen D, Smith BL, Chen CH, Disatnik MH, Ron D. Interaction of protein kinase C with RACKI, a receptor for activated C-kinase: A role in β protein kinase C mediated signal transduction Biochemical Society Transactions. 23: 596-600. PMID 8566424 DOI: 10.1042/Bst0230596  0.183
1997 Ron D. TLS-CHOP and the role of RNA-binding proteins in oncogenic transformation. Current Topics in Microbiology and Immunology. 220: 131-42. PMID 9103679 DOI: 10.1007/978-3-642-60479-9_8  0.182
2002 Trowbridge JM, Rudisill JA, Ron D, Gallo RL. Dermatan sulfate binds and potentiates activity of keratinocyte growth factor (FGF-7). The Journal of Biological Chemistry. 277: 42815-20. PMID 12215437 DOI: 10.1074/Jbc.M204959200  0.177
2006 He DY, Ron D. Autoregulation of glial cell line-derived neurotrophic factor expression: implications for the long-lasting actions of the anti-addiction drug, Ibogaine. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2420-2. PMID 17023388 DOI: 10.1096/fj.06-6394fje  0.177
2021 Ordóñez A, Harding HP, Marciniak SJ, Ron D. Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers. Cell Reports. 35: 109144. PMID 34010647 DOI: 10.1016/j.celrep.2021.109144  0.176
2006 Sher I, Zisman-Rozen S, Eliahu L, Whitelock JM, Maas-Szabowski N, Yamada Y, Breitkreutz D, Fusenig NE, Arikawa-Hirasawa E, Iozzo RV, Bergman R, Ron D. Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation. The Journal of Biological Chemistry. 281: 5178-87. PMID 16269412 DOI: 10.1074/Jbc.M509500200  0.176
2008 He DY, Ron D. Glial cell line-derived neurotrophic factor reverses ethanol-mediated increases in tyrosine hydroxylase immunoreactivity via altering the activity of heat shock protein 90. The Journal of Biological Chemistry. 283: 12811-8. PMID 18343820 DOI: 10.1074/jbc.M706216200  0.175
2003 Yaka R, He DY, Phamluong K, Ron D. Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1. The Journal of Biological Chemistry. 278: 9630-8. PMID 12524444 DOI: 10.1074/Jbc.M209141200  0.172
2020 Wiseman RL, Chin KT, Haynes CM, Stanhill A, Xu CF, Roguev A, Krogan NJ, Neubert TA, Ron D. Correction: Thioredoxin-related protein 32 is an arsenite-regulated thiol reductase of the proteasome 19 S particle. The Journal of Biological Chemistry. 295: 9267. PMID 32620695 DOI: 10.1074/jbc.AAC120.014712  0.172
2020 Preissler S, Rato C, Yan Y, Perera LA, Czako A, Ron D. Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes. Elife. 9. PMID 33295873 DOI: 10.7554/eLife.62601  0.168
1999 Berman B, Ostrovsky O, Shlissel M, Lang T, Regan D, Vlodavsky I, Ishai-Michaeli R, Ron D. Similarities and differences between the effects of heparin and glypican-1 on the bioactivity of acidic fibroblast growth factor and the keratinocyte growth factor. The Journal of Biological Chemistry. 274: 36132-8. PMID 10593896  0.168
2000 Ron D, Vagts AJ, Dohrman DP, Yaka R, Jiang Z, Yao L, Crabbe J, Grisel JE, Diamond I. Uncoupling of betaIIPKC from its targeting protein RACK1 in response to ethanol in cultured cells and mouse brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 2303-14. PMID 11053252 DOI: 10.1096/Fj.00-0143Com  0.166
2003 Vagts AJ, He DY, Yaka R, Ron D. Cellular adaptation to chronic ethanol results in altered compartmentalization and function of the scaffolding protein RACK1. Alcoholism, Clinical and Experimental Research. 27: 1599-605. PMID 14574230 DOI: 10.1097/01.Alc.0000089957.63597.A4  0.161
2013 Jeanblanc J, Logrip ML, Janak PH, Ron D. BDNF-mediated regulation of ethanol consumption requires the activation of the MAP kinase pathway and protein synthesis. The European Journal of Neuroscience. 37: 607-12. PMID 23189980 DOI: 10.1111/Ejn.12067  0.161
2013 Ron D, Messing RO. Signaling pathways mediating alcohol effects. Current Topics in Behavioral Neurosciences. 13: 87-126. PMID 21877259 DOI: 10.1007/7854_2011_161  0.159
2008 Patel VN, Likar KM, Zisman-Rozen S, Cowherd SN, Lassiter KS, Sher I, Yates EA, Turnbull JE, Ron D, Hoffman MP. Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation. The Journal of Biological Chemistry. 283: 9308-17. PMID 18230614 DOI: 10.1074/jbc.M709995200  0.159
2005 Kreuger J, Jemth P, Sanders-Lindberg E, Eliahu L, Ron D, Basilico C, Salmivirta M, Lindahl U. Fibroblast growth factors share binding sites in heparan sulphate. The Biochemical Journal. 389: 145-50. PMID 15769253 DOI: 10.1042/Bj20042129  0.156
2000 Sher I, Lang T, Lubinsky-Mink S, Kuhn J, Adir N, Chatterjee S, Schomburg D, Ron D. Identification of residues important both for primary receptor binding and specificity in fibroblast growth factor-7. The Journal of Biological Chemistry. 275: 34881-6. PMID 10950949 DOI: 10.1074/jbc.M003293200  0.156
1979 Ron D. The reticuloendothelial system and rheumatoid arthritis. The Lancet. 314: 901. PMID 90988 DOI: 10.1016/S0140-6736(79)92712-0  0.155
1999 Sher I, Weizman A, Lubinsky-Mink S, Lang T, Adir N, Schomburg D, Ron D. Mutations uncouple human fibroblast growth factor (FGF)-7 biological activity and receptor binding and support broad specificity in the secondary receptor binding site of FGFs. The Journal of Biological Chemistry. 274: 35016-22. PMID 10574979 DOI: 10.1074/jbc.274.49.35016  0.154
2000 Kopito RR, Ron D. Conformational disease. Nature Cell Biology. 2: E207-9. PMID 11056553 DOI: 10.1038/35041139  0.154
2008 Ron D, Fuchs Y, Chorev DS. Know thy Sef: a novel class of feedback antagonists of receptor tyrosine kinase signaling. The International Journal of Biochemistry & Cell Biology. 40: 2040-52. PMID 18450498 DOI: 10.1016/j.biocel.2008.03.013  0.154
2008 Grothe C, Claus P, Haastert K, Lutwak E, Ron D. Expression and regulation of Sef, a novel signaling inhibitor of receptor tyrosine kinases-mediated signaling in the nervous system. Acta Histochemica. 110: 155-62. PMID 17980404 DOI: 10.1016/j.acthis.2007.08.006  0.151
2009 Carnicella S, Ron D. GDNF--a potential target to treat addiction. Pharmacology & Therapeutics. 122: 9-18. PMID 19136027 DOI: 10.1016/J.Pharmthera.2008.12.001  0.15
2005 Harduf H, Halperin E, Reshef R, Ron D. Sef is synexpressed with FGFs during chick embryogenesis and its expression is differentially regulated by FGFs in the developing limb. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 301-12. PMID 15844098 DOI: 10.1002/dvdy.20364  0.15
2003 Sher I, Yeh BK, Mohammadi M, Adir N, Ron D. Structure-based mutational analyses in FGF7 identify new residues involved in specific interaction with FGFR2IIIb. Febs Letters. 552: 150-4. PMID 14527678 DOI: 10.1016/S0014-5793(03)00909-8  0.144
2015 Legastelois R, Darcq E, Wegner SA, Lombroso PJ, Ron D. Striatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking. Plos One. 10: e0127408. PMID 25992601 DOI: 10.1371/Journal.Pone.0127408  0.143
1991 Perego R, Ron D, Kruh G. Arg, A 145 Kd protein with tyrosine kinase activity belongs to the Abelson sub-family of non receptor tyrosine kinases European Journal of Cancer and Clinical Oncology. 27: S68. DOI: 10.1016/0277-5379(91)91462-R  0.137
2003 Yeh BK, Igarashi M, Eliseenkova AV, Plotnikov AN, Sher I, Ron D, Aaronson SA, Mohammadi M. Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors. Proceedings of the National Academy of Sciences of the United States of America. 100: 2266-71. PMID 12591959 DOI: 10.1073/Pnas.0436500100  0.136
1995 Ron D, Luo J, Mochly-Rosen D. C2 region-derived peptides inhibit translocation and function of β protein kinase C in vivo Journal of Biological Chemistry. 270: 24180-24187. PMID 7592622 DOI: 10.1074/Jbc.270.41.24180  0.136
2007 Zisman-Rozen S, Fink D, Ben-Izhak O, Fuchs Y, Brodski A, Kraus MH, Bejar J, Ron D. Downregulation of Sef, an inhibitor of receptor tyrosine kinase signaling, is common to a variety of human carcinomas. Oncogene. 26: 6093-8. PMID 17420726 DOI: 10.1038/sj.onc.1210424  0.134
2010 Wang J, Carnicella S, Ahmadiantehrani S, He DY, Barak S, Kharazia V, Ben Hamida S, Zapata A, Shippenberg TS, Ron D. Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14502-12. PMID 20980608 DOI: 10.1523/Jneurosci.3909-10.2010  0.133
2013 Sparta DR, Hopf FW, Gibb SL, Cho SL, Stuber GD, Messing RO, Ron D, Bonci A. Binge ethanol-drinking potentiates corticotropin releasing factor R1 receptor activity in the ventral tegmental area. Alcoholism, Clinical and Experimental Research. 37: 1680-7. PMID 23763790 DOI: 10.1111/acer.12153  0.132
2014 Darcq E, Hamida SB, Wu S, Phamluong K, Kharazia V, Xu J, Lombroso P, Ron D. Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption. Journal of Neurochemistry. 129: 1024-34. PMID 24588427 DOI: 10.1111/Jnc.12701  0.129
2011 Gibb SL, Hamida SB, Lanfranco MF, Ron D. Ethanol-induced increase in Fyn kinase activity in the dorsomedial striatum is associated with subcellular redistribution of protein tyrosine phosphatase α. Journal of Neurochemistry. 119: 879-89. PMID 21919909 DOI: 10.1111/j.1471-4159.2011.07485.x  0.129
2002 Ostrovsky O, Berman B, Gallagher J, Mulloy B, Fernig DG, Delehedde M, Ron D. Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes. The Journal of Biological Chemistry. 277: 2444-53. PMID 11714710 DOI: 10.1074/Jbc.M108540200  0.122
2002 Yaka R, Thornton C, Vagts AJ, Phamluong K, Bonci A, Ron D. NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1. Proceedings of the National Academy of Sciences of the United States of America. 99: 5710-5. PMID 11943848 DOI: 10.1073/Pnas.062046299  0.121
2005 Ron D, Jurd R. The "ups and downs" of signaling cascades in addiction. Science's Stke : Signal Transduction Knowledge Environment. 2005: re14. PMID 16278489 DOI: 10.1126/stke.3092005re14  0.121
2008 Logrip ML, Janak PH, Ron D. Dynorphin is a downstream effector of striatal BDNF regulation of ethanol intake. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2393-404. PMID 18310464 DOI: 10.1096/fj.07-099135  0.115
2014 Neasta J, Barak S, Hamida SB, Ron D. mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse. Journal of Neurochemistry. 130: 172-84. PMID 24666346 DOI: 10.1111/Jnc.12725  0.115
1999 Gengrinovitch S, Berman B, David G, Witte L, Neufeld G, Ron D. Glypican-1 is a VEGF165 binding proteoglycan that acts as an extracellular chaperone for VEGF165. The Journal of Biological Chemistry. 274: 10816-22. PMID 10196157  0.114
2006 Shaoul R, Eliahu L, Sher I, Hamlet Y, Miselevich I, Goldshmidt O, Ron D. Elevated expression of FGF7 protein is common in human gastric diseases. Biochemical and Biophysical Research Communications. 350: 825-33. PMID 17049492 DOI: 10.1016/j.bbrc.2006.08.198  0.111
2006 Jeanblanc J, He DY, McGough NN, Logrip ML, Phamluong K, Janak PH, Ron D. The dopamine D3 receptor is part of a homeostatic pathway regulating ethanol consumption. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1457-64. PMID 16452669 DOI: 10.1523/Jneurosci.3786-05.2006  0.11
2003 Thornton C, Yaka R, Dinh S, Ron D. H-Ras modulates N-methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity. The Journal of Biological Chemistry. 278: 23823-9. PMID 12695509 DOI: 10.1074/Jbc.M302389200  0.109
2013 Ben Hamida S, Darcq E, Wang J, Wu S, Phamluong K, Kharazia V, Ron D. Protein tyrosine phosphatase α in the dorsomedial striatum promotes excessive ethanol-drinking behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14369-78. PMID 24005290 DOI: 10.1523/Jneurosci.1954-13.2013  0.104
2010 Carnicella S, He DY, Yowell QV, Glick SD, Ron D. Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration. Addiction Biology. 15: 424-33. PMID 21040239 DOI: 10.1111/J.1369-1600.2010.00251.X  0.102
2007 Newton PM, Ron D. Protein kinase C and alcohol addiction. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 55: 570-7. PMID 17566760 DOI: 10.1016/j.phrs.2007.04.008  0.102
2015 Logrip ML, Barak S, Warnault V, Ron D. Corticostriatal BDNF and alcohol addiction. Brain Research. PMID 25801118 DOI: 10.1016/J.Brainres.2015.03.025  0.1
2003 Rudd T, Gallagher JT, Ron D, Nichols RJ, Fernig DG. A gravimetric analysis of protein-oligosaccharide interactions. Biochemical Society Transactions. 31: 349-51. PMID 12653635 DOI: 10.1042/Bst0310349  0.1
2006 Woodward JJ, Ron D, Winder D, Roberto M. From blue states to up states: a regional view of NMDA-ethanol interactions. Alcoholism, Clinical and Experimental Research. 30: 359-67. PMID 16441285 DOI: 10.1111/J.1530-0277.2006.00040.X  0.098
2010 Neasta J, Ben Hamida S, Yowell Q, Carnicella S, Ron D. Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders. Proceedings of the National Academy of Sciences of the United States of America. 107: 20093-8. PMID 21041654 DOI: 10.1073/Pnas.1005554107  0.096
2011 Gibb SL, Jeanblanc J, Barak S, Yowell QV, Yaka R, Ron D. Lyn kinase regulates mesolimbic dopamine release: implication for alcohol reward. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2180-7. PMID 21307254 DOI: 10.1523/Jneurosci.5540-10.2011  0.095
2016 Beckley JT, Laguesse S, Phamluong K, Morisot N, Wegner SA, Ron D. The First Alcohol Drink Triggers mTORC1-Dependent Synaptic Plasticity in Nucleus Accumbens Dopamine D1 Receptor Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 701-13. PMID 26791202 DOI: 10.1523/JNEUROSCI.2254-15.2016  0.09
2005 He DY, McGough NN, Ravindranathan A, Jeanblanc J, Logrip ML, Phamluong K, Janak PH, Ron D. Glial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 619-28. PMID 15659598 DOI: 10.1523/Jneurosci.3959-04.2005  0.087
2006 Janak PH, Wolf FW, Heberlein U, Pandey SC, Logrip ML, Ron D. BIG news in alcohol addiction: new findings on growth factor pathways BDNF, insulin, and GDNF. Alcoholism, Clinical and Experimental Research. 30: 214-21. PMID 16441270 DOI: 10.1111/J.1530-0277.2006.00026.X  0.086
2004 McGough NN, He DY, Logrip ML, Jeanblanc J, Phamluong K, Luong K, Kharazia V, Janak PH, Ron D. RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10542-52. PMID 15548669 DOI: 10.1523/Jneurosci.3714-04.2004  0.086
2008 Lackey JG, Ron D, Damha MJ, Harding HP. Toward the discovery of new antifungal agents: the design and validation of a novel 2'P-RNA probe and high throughput screening assay against 2'-phosphotransferase Tpt1p. Nucleic Acids Symposium Series (2004). 475-6. PMID 18776460 DOI: 10.1093/nass/nrn241  0.084
2006 Schilström B, Yaka R, Argilli E, Suvarna N, Schumann J, Chen BT, Carman M, Singh V, Mailliard WS, Ron D, Bonci A. Cocaine enhances NMDA receptor-mediated currents in ventral tegmental area cells via dopamine D5 receptor-dependent redistribution of NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8549-58. PMID 16914681 DOI: 10.1523/Jneurosci.5179-05.2006  0.083
2010 Wang J, Lanfranco MF, Gibb SL, Yowell QV, Carnicella S, Ron D. Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10187-98. PMID 20668202 DOI: 10.1523/Jneurosci.2268-10.2010  0.082
2009 Carnicella S, Ahmadiantehrani S, He DY, Nielsen CK, Bartlett SE, Janak PH, Ron D. Cabergoline decreases alcohol drinking and seeking behaviors via glial cell line-derived neurotrophic factor. Biological Psychiatry. 66: 146-53. PMID 19232578 DOI: 10.1016/J.Biopsych.2008.12.022  0.082
2007 Wang J, Carnicella S, Phamluong K, Jeanblanc J, Ronesi JA, Chaudhri N, Janak PH, Lovinger DM, Ron D. Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum: implications for alcohol drinking behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3593-602. PMID 17392475 DOI: 10.1523/Jneurosci.4749-06.2007  0.082
2011 Neasta J, Ben Hamida S, Yowell QV, Carnicella S, Ron D. AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors. Biological Psychiatry. 70: 575-82. PMID 21549353 DOI: 10.1016/J.Biopsych.2011.03.019  0.08
2011 Wang J, Lanfranco MF, Gibb SL, Ron D. Ethanol-mediated long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum. Channels (Austin, Tex.). 5: 205-9. PMID 21289476 DOI: 10.4161/Chan.5.3.14856  0.079
2004 Ron D. Signaling cascades regulating NMDA receptor sensitivity to ethanol. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10: 325-36. PMID 15271260 DOI: 10.1177/1073858404263516  0.079
2003 Yaka R, Phamluong K, Ron D. Scaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3623-32. PMID 12736333 DOI: 10.1523/Jneurosci.23-09-03623.2003  0.079
2013 Barak S, Liu F, Ben Hamida S, Yowell QV, Neasta J, Kharazia V, Janak PH, Ron D. Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse. Nature Neuroscience. 16: 1111-7. PMID 23792945 DOI: 10.1038/Nn.3439  0.076
2005 Suvarna N, Borgland SL, Wang J, Phamluong K, Auberson YP, Bonci A, Ron D. Ethanol alters trafficking and functional N-methyl-D-aspartate receptor NR2 subunit ratio via H-Ras. The Journal of Biological Chemistry. 280: 31450-9. PMID 16009711 DOI: 10.1074/jbc.M504120200  0.075
2005 Ron D, Janak PH. GDNF and addiction. Reviews in the Neurosciences. 16: 277-85. PMID 16519005 DOI: 10.1515/Revneuro.2005.16.4.277  0.074
2006 Szumlinski KK, Abernathy KE, Oleson EB, Klugmann M, Lominac KD, He DY, Ron D, During M, Kalivas PW. Homer isoforms differentially regulate cocaine-induced neuroplasticity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 768-77. PMID 16160706 DOI: 10.1038/Sj.Npp.1300890  0.074
2015 Wang J, Cheng Y, Wang X, Roltsch Hellard E, Ma T, Gil H, Ben Hamida S, Ron D. Alcohol Elicits Functional and Structural Plasticity Selectively in Dopamine D1 Receptor-Expressing Neurons of the Dorsomedial Striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11634-43. PMID 26290240 DOI: 10.1523/Jneurosci.0003-15.2015  0.072
2008 Carnicella S, Kharazia V, Jeanblanc J, Janak PH, Ron D. GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. Proceedings of the National Academy of Sciences of the United States of America. 105: 8114-9. PMID 18541917 DOI: 10.1073/Pnas.0711755105  0.072
2015 Warnault V, Darcq E, Morisot N, Phamluong K, Wilbrecht L, Massa SM, Longo FM, Ron D. The BDNF Valine 68 to Methionine Polymorphism Increases Compulsive Alcohol Drinking in Mice that Is Reversed by Tropomyosin Receptor Kinase B Activation. Biological Psychiatry. PMID 26204799 DOI: 10.1016/J.Biopsych.2015.06.007  0.07
2009 Logrip ML, Janak PH, Ron D. Escalating ethanol intake is associated with altered corticostriatal BDNF expression. Journal of Neurochemistry. 109: 1459-68. PMID 19453942 DOI: 10.1111/j.1471-4159.2009.06073.x  0.07
2009 Ron D, Hughes L. Energy security in the residential sector: An examination of rapid responses to home heating emergencies 2009 Ieee Electrical Power and Energy Conference, Epec 2009. DOI: 10.1109/EPEC.2009.5420986  0.068
2003 Gamady A, Koren R, Ron D, Liberman UA, Ravid A. Vitamin D enhances mitogenesis mediated by keratinocyte growth factor receptor in keratinocytes. Journal of Cellular Biochemistry. 89: 440-9. PMID 12761878 DOI: 10.1002/jcb.10508  0.067
2009 Rewal M, Jurd R, Gill TM, He DY, Ron D, Janak PH. Alpha4-containing GABAA receptors in the nucleus accumbens mediate moderate intake of alcohol. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 543-9. PMID 19144854 DOI: 10.1523/JNEUROSCI.3199-08.2009  0.067
2022 Russo A, Ron DA, Rasschaert M, Prenen H, Mehra R, Scilla K, Pauwels P, Rolfo C. Is There Room for Personalized Medicine in Small-Cell Lung Cancer (SCLC)? Remarkable Activity of Pazopanib in Refractory FGFR1-Amplified ED-SCLC. Jco Precision Oncology. 3: 1-8. PMID 35100736 DOI: 10.1200/PO.19.00243  0.066
2012 Wang J, Ben Hamida S, Darcq E, Zhu W, Gibb SL, Lanfranco MF, Carnicella S, Ron D. Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15124-32. PMID 23100433 DOI: 10.1523/Jneurosci.2783-12.2012  0.066
2012 Ben Hamida S, Neasta J, Lasek AW, Kharazia V, Zou M, Carnicella S, Janak PH, Ron D. The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15849-58. PMID 23136424 DOI: 10.1523/Jneurosci.2846-12.2012  0.066
2014 Darcq E, Warnault V, Phamluong K, Besserer GM, Liu F, Ron D. MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption. Molecular Psychiatry. PMID 25330738 DOI: 10.1038/mp.2014.120  0.063
2014 Darcq E, Warnault V, Phamluong K, Besserer GM, Liu F, Ron D. MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption. Molecular Psychiatry. PMID 25385365 DOI: 10.1038/Mp.2014.155  0.063
2015 Ron D, Servedio RA. Exponentially Improved Algorithms and Lower Bounds for Testing Signed Majorities Algorithmica. 72: 400-429. DOI: 10.1007/S00453-013-9858-0  0.061
2013 Ron D, Tsur G. On approximating the number of relevant variables in a function Acm Transactions On Computation Theory. 5. DOI: 10.1145/2493246.2493250  0.061
2009 Carnicella S, Ahmadiantehrani S, Janak PH, Ron D. GDNF is an endogenous negative regulator of ethanol-mediated reward and of ethanol consumption after a period of abstinence. Alcoholism, Clinical and Experimental Research. 33: 1012-24. PMID 19302086 DOI: 10.1111/J.1530-0277.2009.00922.X  0.061
2014 Ahmadiantehrani S, Barak S, Ron D. GDNF is a novel ethanol-responsive gene in the VTA: implications for the development and persistence of excessive drinking. Addiction Biology. 19: 623-33. PMID 23298382 DOI: 10.1111/Adb.12028  0.061
2009 Jeanblanc J, He DY, Carnicella S, Kharazia V, Janak PH, Ron D. Endogenous BDNF in the dorsolateral striatum gates alcohol drinking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13494-502. PMID 19864562 DOI: 10.1523/Jneurosci.2243-09.2009  0.06
2011 Chen G, Cuzon Carlson VC, Wang J, Beck A, Heinz A, Ron D, Lovinger DM, Buck KJ. Striatal involvement in human alcoholism and alcohol consumption, and withdrawal in animal models. Alcoholism, Clinical and Experimental Research. 35: 1739-48. PMID 21615425 DOI: 10.1111/J.1530-0277.2011.01520.X  0.059
2009 Raskhodnikova S, Ron D, Shpilka A, Smith A. Strong lower bounds for approximating distribution support size and the distinct elements problem Siam Journal On Computing. 39: 813-842. DOI: 10.1137/070701649  0.059
1999 Miller M, Shohat B, Shaklai M, Ron D, Rapaport L, Gordon C, Kott E, Bodemer W, Hannig H, Hunsmann G. Transmission of HTLV-I to rats via peripheral blood mononuclear cells and serum from a patient with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) with amyotrophic lateral sclerosis (ALS)-like features. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 20: 403-7. PMID 10096586  0.058
2011 Nie H, Rewal M, Gill TM, Ron D, Janak PH. Extrasynaptic delta-containing GABAA receptors in the nucleus accumbens dorsomedial shell contribute to alcohol intake. Proceedings of the National Academy of Sciences of the United States of America. 108: 4459-64. PMID 21368141 DOI: 10.1073/pnas.1016156108  0.058
2012 Rewal M, Donahue R, Gill TM, Nie H, Ron D, Janak PH. Alpha4 subunit-containing GABAA receptors in the accumbens shell contribute to the reinforcing effects of alcohol. Addiction Biology. 17: 309-21. PMID 21507158 DOI: 10.1111/j.1369-1600.2011.00333.x  0.058
2009 Logrip ML, Janak PH, Ron D. Blockade of ethanol reward by the kappa opioid receptor agonist U50,488H. Alcohol (Fayetteville, N.Y.). 43: 359-65. PMID 19671462 DOI: 10.1016/j.alcohol.2009.05.001  0.058
2015 Barak S, Wang J, Ahmadiantehrani S, Ben Hamida S, Kells AP, Forsayeth J, Bankiewicz KS, Ron D. Glial cell line-derived neurotrophic factor (GDNF) is an endogenous protector in the mesolimbic system against excessive alcohol consumption and relapse. Addiction Biology. 20: 629-42. PMID 24801661 DOI: 10.1111/Adb.12152  0.056
2013 Warnault V, Darcq E, Levine A, Barak S, Ron D. Chromatin remodeling--a novel strategy to control excessive alcohol drinking. Translational Psychiatry. 3: e231. PMID 23423140 DOI: 10.1038/Tp.2013.4  0.056
2014 Ron D, Shamir A. How did dread pirate roberts acquire and protect his bitcoin wealth? Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8438: 3-15. DOI: 10.1007/978-3-662-44774-1_1  0.054
2011 Barak S, Carnicella S, Yowell QV, Ron D. Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9885-94. PMID 21734280 DOI: 10.1523/Jneurosci.1750-11.2011  0.053
2003 Schechtman D, Mochly-Rosen D, Ron D. Glutathione S-transferase pull-down assay. Methods in Molecular Biology (Clifton, N.J.). 233: 345-50. PMID 12840520 DOI: 10.1385/1-59259-397-6:345  0.052
2003 Yaka R, Tang KC, Camarini R, Janak PH, Ron D. Fyn kinase and NR2B-containing NMDA receptors regulate acute ethanol sensitivity but not ethanol intake or conditioned reward. Alcoholism, Clinical and Experimental Research. 27: 1736-42. PMID 14634488 DOI: 10.1097/01.Alc.0000095924.87729.D8  0.052
2013 Seif T, Chang SJ, Simms JA, Gibb SL, Dadgar J, Chen BT, Harvey BK, Ron D, Messing RO, Bonci A, Hopf FW. Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake. Nature Neuroscience. 16: 1094-100. PMID 23817545 DOI: 10.1038/Nn.3445  0.05
2012 Ron D, Rubinfeld R, Safra M, Samorodnitsky A, Weinstein O. Approximating the influence of monotone Boolean functions in O(√n) query complexity Acm Transactions On Computation Theory. 4. DOI: 10.1145/2382559.2382562  0.049
2009 Carnicella S, Amamoto R, Ron D. Excessive alcohol consumption is blocked by glial cell line-derived neurotrophic factor. Alcohol (Fayetteville, N.Y.). 43: 35-43. PMID 19185208 DOI: 10.1016/J.Alcohol.2008.12.001  0.049
2014 Goldreich O, Ron D. On learning and testing dynamic environments Proceedings - Annual Ieee Symposium On Foundations of Computer Science, Focs. 336-343. DOI: 10.1145/3088509  0.047
2014 Ahmadiantehrani S, Warnault V, Legastelois R, Ron D. From Signaling Pathways to Behavior: The Light and Dark Sides of Alcohol Neurobiology of Alcohol Dependence. 155-171. DOI: 10.1016/B978-0-12-405941-2.00009-2  0.047
2010 Gonen M, Ron D. On the benefits of adaptivity in property testing of dense graphs Algorithmica (New York). 58: 811-830. DOI: 10.1007/S00453-008-9237-4  0.046
2013 Raskhodnikova S, Ron D, Rubinfeld R, Smith A. Sublinear algorithms for approximating string compressibility Algorithmica. 65: 685-709. DOI: 10.1007/S00453-012-9618-6  0.044
2001 Ron D, Swendsen RH. Calculation of effective Hamiltonians for renormalized or non-Hamiltonian systems. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 63: 066128. PMID 11415194 DOI: 10.1103/Physreve.63.066128  0.04
2014 Ron D, Tsur G. Testing properties of sparse images Acm Transactions On Algorithms. 10. DOI: 10.1145/2635806  0.038
2010 Fattal S, Ron D. Approximating the distance to monotonicity in high dimensions Acm Transactions On Algorithms. 6. DOI: 10.1145/1798596.1798605  0.038
2013 Dutta A, Levi R, Ron D, Rubinfeld R. A simple online competitive adaptation of Lempel-Ziv compression with efficient random access support Data Compression Conference Proceedings. 113-122. DOI: 10.1109/DCC.2013.19  0.037
2011 Goldreich O, Ron D. Algorithmic aspects of property testing in the dense graphs model Siam Journal On Computing. 40: 376-445. DOI: 10.1137/090749621  0.036
2012 Ron D, Tsur G. Testing computability by width-two OBDDs Theoretical Computer Science. 420: 64-79. DOI: 10.1016/J.Tcs.2011.11.007  0.035
2022 Sfeir A, Fishell G, Schier AF, Dustin ML, Gan WB, Joyner A, Lehmann R, Ron D, Roth D, Talbot WS, Yelon D, Zychlinsky A. Basic science under threat: Lessons from the Skirball Institute. Cell. 185: 755-758. PMID 35245477 DOI: 10.1016/j.cell.2022.02.008  0.035
2011 Carnicella S, Yowell QV, Ron D. Regulation of operant oral ethanol self-administration: a dose-response curve study in rats. Alcoholism, Clinical and Experimental Research. 35: 116-25. PMID 21039633 DOI: 10.1111/J.1530-0277.2010.01328.X  0.035
2013 Davies DL, Bortolato M, Finn DA, Ramaker MJ, Barak S, Ron D, Liang J, Olsen RW. Recent advances in the discovery and preclinical testing of novel compounds for the prevention and/or treatment of alcohol use disorders. Alcoholism, Clinical and Experimental Research. 37: 8-15. PMID 22671690 DOI: 10.1111/J.1530-0277.2012.01846.X  0.033
2011 Goldreich O, Ron D. On proximity-oblivious testing Siam Journal On Computing. 40: 534-566. DOI: 10.1137/100789646  0.033
2002 Ron D, Swendsen RH. Importance of multispin couplings in renormalized Hamiltonians. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 66: 056106. PMID 12513555 DOI: 10.1103/Physreve.66.056106  0.031
1999 Kearns M, Ron D. Algorithmic stability and sanity-check bounds for leave-one-out cross-validation. Neural Computation. 11: 1427-53. PMID 10423502 DOI: 10.1162/089976699300016304  0.03
2013 Warnault V, Ron D. Chromatin remodeling: a new landscape to treat harmful alcohol-use disorders. Future Medicinal Chemistry. 5: 2011-3. PMID 24215342 DOI: 10.4155/fmc.13.152  0.03
2014 Carnicella S, Ron D, Barak S. Intermittent ethanol access schedule in rats as a preclinical model of alcohol abuse. Alcohol (Fayetteville, N.Y.). 48: 243-52. PMID 24721195 DOI: 10.1016/J.Alcohol.2014.01.006  0.028
2009 Even G, Halldórsson MM, Kaplan L, Ron D. Scheduling with conflicts: Online and offline algorithms Journal of Scheduling. 12: 199-224. DOI: 10.1007/S10951-008-0089-1  0.027
2002 Ron D, Swendsen RH, Brandt A. Inverse Monte Carlo renormalization group transformations for critical phenomena. Physical Review Letters. 89: 275701. PMID 12513219 DOI: 10.1103/Physrevlett.89.275701  0.027
2015 Canonne CL, Ron D, Servedio RA. Testing probability distributions using conditional samples Siam Journal On Computing. 44: 540-616. DOI: 10.1137/130945508  0.026
2014 Czumaj A, Goldreich O, Ron D, Seshadhri C, Shapira A, Sohler C. Finding cycles and trees in sublinear time Random Structures and Algorithms. 45: 139-184. DOI: 10.1002/Rsa.20462  0.025
2013 Ben-Eliezer I, Kaufman T, Krivelevich M, Ron D. Comparing the strength of query types in property testing: The case of k-colorability Computational Complexity. 22: 89-135. DOI: 10.1007/S00037-012-0048-2  0.025
2007 Roberts MA, Alfonzo CG, Manke KJ, Ames WM, Ron DB, Varberg TD. Hyperfine structure in the electronic spectrum of ReO Molecular Physics. 105: 917-921. DOI: 10.1080/00268970601075295  0.022
2014 Becker HC, Ron D. Animal models of excessive alcohol consumption: recent advances and future challenges. Alcohol (Fayetteville, N.Y.). 48: 205-8. PMID 24811154 DOI: 10.1016/J.Alcohol.2014.04.001  0.02
2010 Ron D, Tsur G. Testing computability by width-2 OBDDs where the variable order is unknown Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6078: 131-142. DOI: 10.1007/978-3-642-13073-1_13  0.019
2018 Raez LE, Nogueira A, Santos ES, Dos Santos RS, Franceschini J, Ron DA, Block M, Yamaguchi N, Rolfo C. Challenges in Lung Cancer Screening in Latin America. Journal of Global Oncology. 1-10. PMID 30241252 DOI: 10.1200/JGO.17.00040  0.018
2014 Levi R, Ron D, Rubinfeld R. Testing similar means Siam Journal On Discrete Mathematics. 28: 1699-1724. DOI: 10.1137/120903737  0.018
2014 Levi R, Ron D, Rubinfeld R. Local algorithms for sparse spanning graphs Leibniz International Proceedings in Informatics, Lipics. 28: 826-842. DOI: 10.1007/S00453-019-00612-6  0.017
2011 Gonen M, Ron D, Shavitt Y. Counting stars and other small subgraphs in sublinear-time Siam Journal On Discrete Mathematics. 25: 1365-1411. DOI: 10.1137/100783066  0.017
2011 Orenstein Y, Ron D. Testing Eulerianity and connectivity in directed sparse graphs Theoretical Computer Science. 412: 6390-6408. DOI: 10.1016/J.Tcs.2011.06.038  0.016
2009 Goldreichy O, Ron D. On proximity oblivious testing Proceedings of the Annual Acm Symposium On Theory of Computing. 141-150. DOI: 10.1145/1536414.1536436  0.014
2013 Goldreich O, Goldwasser S, Ron D. On the possibilities and limitations of pseudodeterministic algorithms Itcs 2013 - Proceedings of the 2013 Acm Conference On Innovations in Theoretical Computer Science. 127-137. DOI: 10.1145/2422436.2422453  0.012
2010 Ron D, Safro I, Brandt A. A fast multigrid algorithm for energy minimization under planar density constraints Multiscale Modeling and Simulation. 8: 1599-1620. DOI: 10.1137/090771995  0.011
2015 Levi R, Ron D. A quasi-polynomial time partition oracle for graphs with an excluded minor Acm Transactions On Algorithms. 11. DOI: 10.1145/2629508  0.01
2015 Parnas M, Ron D, Rubinfeld R. Testing parenthesis languages Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2129: 261-272.  0.01
2015 Parnas M, Ron D, Samorodnitsky A. Proclaiming dictators and juntas or testing boolean formulae Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2129: 273-285.  0.01
2014 Even G, Medina M, Ron D. Deterministic stateless centralized local algorithms for bounded degree graphs Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8737: 394-405. DOI: 10.1007/978-3-662-44777-2_33  0.01
2014 Canonne C, Ron D, Servedio RA. Testing equivalence between distributions using conditional samples Proceedings of the Annual Acm-Siam Symposium On Discrete Algorithms. 1174-1192.  0.01
2013 Ron D, Shamir A. Quantitative analysis of the full Bitcoin transaction graph Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7859: 6-24. DOI: 10.1007/978-3-642-39884-1_2  0.01
2012 Onak K, Ron D, Rosen M, Rubinfeld R. A near-optimal sublinear-time algorithm for approximating the minimum vertex cover size Proceedings of the Annual Acm-Siam Symposium On Discrete Algorithms. 1123-1131.  0.01
2011 Ron D, Safro I, Brandt A. Relaxation-based coarsening and multiscale graph organization Multiscale Modeling and Simulation. 9: 407-423. DOI: 10.1137/100791142  0.01
2011 Goldreich O, Ron D. On testing expansion in bounded-degree graphs Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6650: 68-75. DOI: 10.1007/978-3-642-22670-0_9  0.01
2010 Ben-Eliezer I, Kaufman T, Krivelevich M, Ron D. Comparing the strength of query types in property testing: The case of testing k-colorability Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6390: 253-259. DOI: 10.1007/978-3-642-16367-8_17  0.01
2010 Dolev E, Ron D. Distribution-free testing algorithms for monomials with a sublinear number of queries Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6302: 531-544. DOI: 10.1007/978-3-642-15369-3_40  0.01
2010 Gonen M, Ron D, Shavitt Y. Counting stars and other small subgraphs in sublinear time Proceedings of the Annual Acm-Siam Symposium On Discrete Algorithms. 99-116.  0.01
2010 Woodbury DP, Parish JJ, Parish AS, Swanzy M, Ron D, Mortari D, Junkins JL. Stellar positioning system (Part II): Improving accuracy during implementation Navigation, Journal of the Institute of Navigation. 57: 13-24.  0.01
2009 Ron D. Algorithmic and analysis techniques in property testing Foundations and Trends in Theoretical Computer Science. 5: 73-205. DOI: 10.1561/0400000029  0.01
2009 Marko S, Ron D. Approximating the distance to properties in bounded-degree and general sparse graphs Acm Transactions On Algorithms. 5. DOI: 10.1145/1497290.1497298  0.01
2009 Ron D, Tsur G. Testing computability by width two OBDDs Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5687: 686-699. DOI: 10.1007/978-3-642-03685-9_51  0.01
2008 Ron D. Property testing: A learning theory perspective Foundations and Trends in Machine Learning. 1: 307-402. DOI: 10.1561/2200000004  0.01
2003 Olive MF, Ron D. Alcohol addiction. Methods in Molecular Biology (Clifton, N.J.). 233: 555-70. PMID 12840534 DOI: 10.1385/1-59259-397-6:555  0.01
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