| Year |
Citation |
Score |
| 2020 |
Reshetnyak YK, Moshnikova A, Andreev OA, Engelman DM. Targeting Acidic Diseased Tissues by pH-Triggered Membrane-Associated Peptide Folding. Frontiers in Bioengineering and Biotechnology. 8: 335. PMID 32411684 DOI: 10.3389/Fbioe.2020.00335 |
0.367 |
|
| 2020 |
Slaybaugh G, Weerakkody D, Engelman DM, Andreev OA, Reshetnyak YK. Kinetics of pHLIP peptide insertion into and exit from a membrane. Proceedings of the National Academy of Sciences of the United States of America. PMID 32409607 DOI: 10.1073/Pnas.1917857117 |
0.396 |
|
| 2020 |
Kaplan AR, Pham H, Liu Y, Oyaghire S, Bahal R, Engelman DM, Glazer PM. Ku80-targeted pH-sensitive peptide-PNA conjugates are tumor selective and sensitize cancer cells to ionizing radiation. Molecular Cancer Research : McR. PMID 32098827 DOI: 10.1158/1541-7786.Mcr-19-0661 |
0.314 |
|
| 2019 |
Svoronos AA, Bahal R, Pereira MC, Barrera FN, Deacon JC, Bosenberg M, DiMaio D, Glazer PM, Engelman DM. Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules using a pH-Low Insertion Peptide. Molecular Pharmaceutics. PMID 31855437 DOI: 10.1021/Acs.Molpharmaceut.9B00883 |
0.384 |
|
| 2019 |
Paralkar V, Aiello RJ, Marshall D, Csengery J, Bourassa P, Zhang Q, Robinson BS, Lopresti-Morrow L, Bechtold J, Tylaska L, Paradis T, Slaybaugh G, Visca H, Moshnikova A, Weerakkody D, ... ... Engelman D, et al. Abstract 2981: Targeting solid tumor acidic microenvironment with an alphalex PARP inhibitor Cancer Research. 79: 2981-2981. DOI: 10.1158/1538-7445.Am2019-2981 |
0.313 |
|
| 2019 |
Reshetnyak YK, Andreev OA, Engelman D. Abstract A102: pHLIP technology for targeting acidity at surface of tumor cells and extracellular and intracellular delivery of imaging and therapeutic agents Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-A102 |
0.419 |
|
| 2018 |
Karabadzhak AG, Weerakkody D, Deacon J, Andreev OA, Reshetnyak YK, Engelman DM. Bilayer Thickness and Curvature Influence Binding and Insertion of a pHLIP Peptide. Biophysical Journal. 114: 2107-2115. PMID 29742404 DOI: 10.1016/J.Bpj.2018.03.036 |
0.473 |
|
| 2018 |
Wyatt LC, Moshnikova A, Crawford T, Engelman DM, Andreev OA, Reshetnyak YK. Peptides of pHLIP family for targeted intracellular and extracellular delivery of cargo molecules to tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507241 DOI: 10.1073/Pnas.1715350115 |
0.392 |
|
| 2017 |
Karabadzhak AG, Petti LM, Barrera FN, Edwards APB, Moya-Rodríguez A, Polikanov YS, Freites JA, Tobias DJ, Engelman DM, DiMaio D. Two transmembrane dimers of the bovine papillomavirus E5 oncoprotein clamp the PDGF β receptor in an active dimeric conformation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808001 DOI: 10.1073/Pnas.1705622114 |
0.377 |
|
| 2017 |
Wyatt LC, Lewis JS, Andreev OA, Reshetnyak YK, Engelman DM. Applications of pHLIP Technology for Cancer Imaging and Therapy. Trends in Biotechnology. PMID 28438340 DOI: 10.1016/J.Tibtech.2017.03.014 |
0.357 |
|
| 2016 |
Anderson M, Moshnikova A, Engelman DM, Reshetnyak YK, Andreev OA. Probe for the measurement of cell surface pH in vivo and ex vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 27382181 DOI: 10.1073/Pnas.1608247113 |
0.317 |
|
| 2016 |
Moshnikova A, Anderson M, Adochite R, Engelman DM, Andreev OA, Reshetnyak YK. Abstract 4250: pHLIP® technology for imaging acidic tumors Cancer Research. 76: 4250-4250. DOI: 10.1158/1538-7445.Am2016-4250 |
0.348 |
|
| 2016 |
Engelman D, Reshetnyak YK, Andreev OA. pHLIP®: Uses in Measuring Cell Surface pH, Imaging Tumors, and Delivering Therapeutics Biophysical Journal. 110: 418a. DOI: 10.1016/J.Bpj.2015.11.2259 |
0.379 |
|
| 2015 |
Popot JL, Engelman DM. Membranes do not tell proteins how to fold. Biochemistry. PMID 26649989 DOI: 10.1021/Acs.Biochem.5B01134 |
0.474 |
|
| 2015 |
Heim EN, Marston JL, Federman RS, Edwards AP, Karabadzhak AG, Petti LM, Engelman DM, DiMaio D. Biologically active LIL proteins built with minimal chemical diversity. Proceedings of the National Academy of Sciences of the United States of America. 112: E4717-25. PMID 26261320 DOI: 10.1073/Pnas.1514230112 |
0.36 |
|
| 2015 |
Tapmeier TT, Moshnikova A, Beech J, Allen D, Kinchesh P, Smart S, Harris A, McIntyre A, Engelman DM, Andreev OA, Reshetnyak YK, Muschel RJ. The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions. Proceedings of the National Academy of Sciences of the United States of America. 112: 9710-5. PMID 26195776 DOI: 10.1073/Pnas.1509488112 |
0.306 |
|
| 2015 |
Deacon JC, Engelman DM, Barrera FN. Targeting acidity in diseased tissues: mechanism and applications of the membrane-inserting peptide, pHLIP. Archives of Biochemistry and Biophysics. 565: 40-8. PMID 25444855 DOI: 10.1016/J.Abb.2014.11.002 |
0.433 |
|
| 2015 |
Karabadzhak AG, Weerakkody D, Andreev OA, Reshetnyak YK, Engelman DM. Lipid Composition Influences the Insertion and Folding of pHLIP Peptides Biophysical Journal. 108: 555a. DOI: 10.1016/J.Bpj.2014.11.3042 |
0.475 |
|
| 2015 |
Engelman DM, Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera FN, Liu C, Svoronos A, Braddock DT, Glazer PM, Saltzman WM, Slack FJ. pHLIP® Targeting and Delivery of PNA to Silence MicroRNA in Tumor Cells§ Biophysical Journal. 108: 552a. DOI: 10.1016/J.Bpj.2014.11.3029 |
0.322 |
|
| 2014 |
Karabadzhak AG, An M, Yao L, Langenbacher R, Moshnikova A, Adochite RC, Andreev OA, Reshetnyak YK, Engelman DM. pHLIP-FIRE, a cell insertion-triggered fluorescent probe for imaging tumors demonstrates targeted cargo delivery in vivo. Acs Chemical Biology. 9: 2545-53. PMID 25184440 DOI: 10.1021/Cb500388M |
0.586 |
|
| 2014 |
Cohen EB, Jun SJ, Bears Z, Barrera FN, Alonso M, Engelman DM, DiMaio D. Mapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor. Plos One. 9: e95593. PMID 24788775 DOI: 10.1371/Journal.Pone.0095593 |
0.386 |
|
| 2014 |
Viola-Villegas NT, Carlin SD, Ackerstaff E, Sevak KK, Divilov V, Serganova I, Kruchevsky N, Anderson M, Blasberg RG, Andreev OA, Engelman DM, Koutcher JA, Reshetnyak YK, Lewis JS. Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: 7254-9. PMID 24785505 DOI: 10.1073/Pnas.1405240111 |
0.304 |
|
| 2014 |
Andreev OA, Engelman DM, Reshetnyak YK. Targeting diseased tissues by pHLIP insertion at low cell surface pH. Frontiers in Physiology. 5: 97. PMID 24659971 DOI: 10.3389/Fphys.2014.00097 |
0.4 |
|
| 2014 |
Kohlway A, Pirakitikulr N, Barrera FN, Potapova O, Engelman DM, Pyle AM, Lindenbach BD. Hepatitis C virus RNA replication and virus particle assembly require specific dimerization of the NS4A protein transmembrane domain. Journal of Virology. 88: 628-42. PMID 24173222 DOI: 10.1128/Jvi.02052-13 |
0.322 |
|
| 2014 |
Cheng CJ, Engelman DM, Saltzman M, Slack FJ. Abstract 974: Targeting the tumor microenvironment with antimiRs that exploit oncomiR addiction in lymphoma Cancer Research. 74: 974-974. DOI: 10.1158/1538-7445.Am2014-974 |
0.303 |
|
| 2014 |
Karabadzhak A, Yao L, Langenbacher R, Moshnikova A, Adochite R, An M, Andreev OA, Reshetnyak YK, Engelman DM. Phlip-Fire: A High-Contrast, Insertion-Triggered Fluorescent Probe for Targeting Tumors In Vivo Biophysical Journal. 106: 88a-89a. DOI: 10.1016/J.Bpj.2013.11.561 |
0.607 |
|
| 2014 |
An M, Onyango J, Chung MS, Lapid RJ, Gordon EA, Langenbacher R, Winge-Barnes S, Chandler RA, Engelman DM, Yao L. Towards PHLIP Insertion in the Plasmamembrane of Cancer Cells at Physiological Tumor Acidity Biophysical Journal. 106: 296a. DOI: 10.1016/J.Bpj.2013.11.1724 |
0.798 |
|
| 2014 |
Engelman DM, An M, Andreev OA, Barrera FN, Bahal R, Bosenberg MW, Cheng C, Glazer PM, Karabadzhak A, Reshetnyak YK, Saltzman WM, Slack FJ, Svoronos AA, Thevenin D. Imaging and Treating Tumors by Targeting their Acidity with Phlip, a Ph-Sensitve Insertion Peptide Biophysical Journal. 106: 231a. DOI: 10.1016/J.Bpj.2013.11.1350 |
0.737 |
|
| 2013 |
Fendos J, Barrera FN, Engelman DM. Aspartate embedding depth affects pHLIP's insertion pKa. Biochemistry. 52: 4595-604. PMID 23721379 DOI: 10.1021/Bi400252K |
0.8 |
|
| 2013 |
Weerakkody D, Moshnikova A, Thakur MS, Moshnikova V, Daniels J, Engelman DM, Andreev OA, Reshetnyak YK. Family of pH (low) insertion peptides for tumor targeting. Proceedings of the National Academy of Sciences of the United States of America. 110: 5834-9. PMID 23530249 DOI: 10.1073/Pnas.1303708110 |
0.354 |
|
| 2013 |
Li N, Yin L, Thévenin D, Yamada Y, Limmon G, Chen J, Chow VT, Engelman DM, Engelward BP. Peptide targeting and imaging of damaged lung tissue in influenza-infected mice. Future Microbiology. 8: 257-69. PMID 23374130 DOI: 10.2217/Fmb.12.134 |
0.553 |
|
| 2013 |
Sosunov EA, Anyukhovsky EP, Sosunov AA, Moshnikova A, Wijesinghe D, Engelman DM, Reshetnyak YK, Andreev OA. pH (low) insertion peptide (pHLIP) targets ischemic myocardium. Proceedings of the National Academy of Sciences of the United States of America. 110: 82-6. PMID 23248283 DOI: 10.1073/Pnas.1220038110 |
0.302 |
|
| 2013 |
Svoronos AA, Cheng CJ, Barrera FN, Saltzman WM, Bosenberg MW, Engelman DM. Targeting of Melanoma by pH (Low) Insertion Peptide (pHLIP) Biophysical Journal. 104: 677a. DOI: 10.1016/J.Bpj.2012.11.3740 |
0.399 |
|
| 2013 |
Barrera FN, Karabadzhak AG, Engelman DM. Characterization of an Intermediate for the Formation of the Transmembrane Helix of pHLIP Peptide Biophysical Journal. 104: 596a. DOI: 10.1016/J.Bpj.2012.11.3309 |
0.459 |
|
| 2013 |
Andreev OA, Engelman DM, Reshetnyak YK. Novel Concept of Delivery of Diagnostic and Therapeutic Agents to Cells in Acidic Diseased Tissue using Energy of Membrane-Associated Folding Biophysical Journal. 104: 362a. DOI: 10.1016/J.Bpj.2012.11.2013 |
0.456 |
|
| 2013 |
Yao L, Langenbacher R, Karabadzhak A, Engelman DM, An M. Visualizing pHLIP Insertion in Plasmamembrane and Endosomal Membrane Biophysical Journal. 104: 238a. DOI: 10.1016/J.Bpj.2012.11.1342 |
0.642 |
|
| 2012 |
Barrera FN, Fendos J, Engelman DM. Membrane physical properties influence transmembrane helix formation. Proceedings of the National Academy of Sciences of the United States of America. 109: 14422-7. PMID 22908237 DOI: 10.1073/Pnas.1212665109 |
0.825 |
|
| 2012 |
Karabadzhak AG, Weerakkody D, Wijesinghe D, Thakur MS, Engelman DM, Andreev OA, Markin VS, Reshetnyak YK. Modulation of the pHLIP transmembrane helix insertion pathway. Biophysical Journal. 102: 1846-55. PMID 22768940 DOI: 10.1016/J.Bpj.2012.03.021 |
0.456 |
|
| 2012 |
Fendos J, Engelman D. pHLIP and acidity as a universal biomarker for cancer. The Yale Journal of Biology and Medicine. 85: 29-35. PMID 22461741 |
0.771 |
|
| 2012 |
Macholl S, Morrison MS, Iveson P, Arbo BE, Andreev OA, Reshetnyak YK, Engelman DM, Johannesen E. In vivo pH imaging with (99m)Tc-pHLIP. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 14: 725-34. PMID 22371188 DOI: 10.1007/S11307-012-0549-Z |
0.311 |
|
| 2011 |
Wijesinghe D, Engelman DM, Andreev OA, Reshetnyak YK. Tuning a polar molecule for selective cytoplasmic delivery by a pH (Low) insertion peptide. Biochemistry. 50: 10215-22. PMID 22029270 DOI: 10.1021/Bi2009773 |
0.405 |
|
| 2011 |
Barrera FN, Weerakkody D, Anderson M, Andreev OA, Reshetnyak YK, Engelman DM. Roles of carboxyl groups in the transmembrane insertion of peptides. Journal of Molecular Biology. 413: 359-71. PMID 21888917 DOI: 10.1016/J.Jmb.2011.08.010 |
0.438 |
|
| 2011 |
Matthews EE, Thévenin D, Rogers JM, Gotow L, Lira PD, Reiter LA, Brissette WH, Engelman DM. Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2234-44. PMID 21402716 DOI: 10.1096/Fj.10-178673 |
0.724 |
|
| 2011 |
Reshetnyak YK, Yao L, Zheng S, Kuznetsov S, Engelman DM, Andreev OA. Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 13: 1146-56. PMID 21181501 DOI: 10.1007/S11307-010-0457-Z |
0.362 |
|
| 2011 |
Barrera FN, An M, Wijesinghe DD, Weerakkody DA, Anderson M, Andreev OA, Reshetnyak YK, Engelman DM. Abstract C2: Aspartic acid residues drive the membrane translocation of pHLIP, a therapeutic and imaging agent for solid tumors Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C2 |
0.663 |
|
| 2011 |
Weerakkody DA, Karabadzhak AG, Thakur MS, Rossi B, Engelman DM, Andreev OA, Reshetnyak YK. Correlation between Properties of pHLIP Peptide-Lipid Interaction and Tumor Targeting In Vivo Biophysical Journal. 100: 498a. DOI: 10.1016/J.Bpj.2010.12.2918 |
0.418 |
|
| 2011 |
Karabadzhak AG, Weerakkody D, Thakur MS, Anderson MD, Engelman DM, Andreev OA, Markin VS, Reshetnyak YK. First Step in Folding of Nonconstitutive Membrane Proteins: Spontaneous Insertion of a Polypeptide into a Lipid Bilayer and Formation of Helical Structure Biophysical Journal. 100: 346a. DOI: 10.1016/J.Bpj.2010.12.2088 |
0.488 |
|
| 2010 |
Miyauchi K, Curran AR, Long Y, Kondo N, Iwamoto A, Engelman DM, Matsuda Z. The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein. Retrovirology. 7: 95. PMID 21073746 DOI: 10.1186/1742-4690-7-95 |
0.375 |
|
| 2010 |
An M, Wijesinghe D, Andreev OA, Reshetnyak YK, Engelman DM. pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 107: 20246-50. PMID 21048084 DOI: 10.1073/Pnas.1014403107 |
0.615 |
|
| 2010 |
Andreev OA, Engelman DM, Reshetnyak YK. pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents. Molecular Membrane Biology. 27: 341-52. PMID 20939768 DOI: 10.3109/09687688.2010.509285 |
0.454 |
|
| 2010 |
Patel PV, Gianoulis TA, Bjornson RD, Yip KY, Engelman DM, Gerstein MB. Analysis of membrane proteins in metagenomics: networks of correlated environmental features and protein families. Genome Research. 20: 960-71. PMID 20430783 DOI: 10.1101/Gr.102814.109 |
0.382 |
|
| 2010 |
Andreev OA, Karabadzhak AG, Weerakkody D, Andreev GO, Engelman DM, Reshetnyak YK. pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path. Proceedings of the National Academy of Sciences of the United States of America. 107: 4081-6. PMID 20160113 DOI: 10.1073/Pnas.0914330107 |
0.44 |
|
| 2010 |
Cammett TJ, Jun SJ, Cohen EB, Barrera FN, Engelman DM, Dimaio D. Construction and genetic selection of small transmembrane proteins that activate the human erythropoietin receptor. Proceedings of the National Academy of Sciences of the United States of America. 107: 3447-52. PMID 20142506 DOI: 10.1073/Pnas.0915057107 |
0.383 |
|
| 2010 |
Musial-Siwek M, Karabadzhak A, Andreev OA, Reshetnyak YK, Engelman DM. Tuning the insertion properties of pHLIP. Biochimica Et Biophysica Acta. 1798: 1041-6. PMID 19766589 DOI: 10.1016/J.Bbamem.2009.08.023 |
0.462 |
|
| 2010 |
Engelman DM. An Implication of the Structure of Bacteriorhodopsin: Globular Membrane Proteins are Stabilized by Polar Interactions. Biophysical Journal. 37: 187-8. PMID 19431470 DOI: 10.1016/S0006-3495(82)84662-6 |
0.434 |
|
| 2010 |
Steitz TA, Goldman A, Engelman DM. Quantitative application of the helical hairpin hypothesis to membrane proteins. Biophysical Journal. 37: 124-5. PMID 19431438 DOI: 10.1016/S0006-3495(82)84633-X |
0.414 |
|
| 2010 |
Karabadzhak AG, Weerakkody D, Thakur MS, Andreev GO, Engelman DM, Andreev OA, Reshetnyak YK. Membrane-Associated Folding and Unfolding Biophysical Journal. 98: 88a. DOI: 10.1016/J.Bpj.2009.12.499 |
0.455 |
|
| 2010 |
Barrera FN, Musial-Siwek M, Andreev OA, Reshetnyak YK, Engelman DM. Energy Barriers and Helix Plasticity in the Membrane Insertion of pHLIP Biophysical Journal. 98: 82a. DOI: 10.1016/J.Bpj.2009.12.466 |
0.469 |
|
| 2010 |
Thévenin D, Matthews EE, Rogers JM, An M, Gotow L, Lira PD, Reiter LA, Brissette WH, Engelman DM. Involvement of Transmembrane Helix Dimerization and Rotation in Signaling by the Thrombopoietin Receptor Biophysical Journal. 98: 420a. DOI: 10.1016/J.Bpj.2009.12.2269 |
0.781 |
|
| 2010 |
An M, Wijesinghe D, Andreev OA, Reshetnyak YK, Engelman DM. Cancer Cell Proliferation is Inhibited by Phlip Mediated Delivery of Membrane Impermeable Toxin Phalloidin Biophysical Journal. 98: 277a-278a. DOI: 10.1016/J.Bpj.2009.12.1516 |
0.566 |
|
| 2009 |
Andreev OA, Engelman DM, Reshetnyak YK. Targeting acidic diseased tissue: New technology based on use of the pH (Low) Insertion Peptide (pHLIP). Chimica Oggi. 27: 34-37. PMID 20037661 |
0.313 |
|
| 2009 |
Arinaminpathy Y, Khurana E, Engelman DM, Gerstein MB. Computational analysis of membrane proteins: the largest class of drug targets. Drug Discovery Today. 14: 1130-5. PMID 19733256 DOI: 10.1016/J.Drudis.2009.08.006 |
0.429 |
|
| 2009 |
Thévenin D, An M, Engelman DM. pHLIP-mediated translocation of membrane-impermeable molecules into cells. Chemistry & Biology. 16: 754-62. PMID 19635412 DOI: 10.1016/J.Chembiol.2009.06.006 |
0.753 |
|
| 2009 |
Talbert-Slagle K, Marlatt S, Barrera FN, Khurana E, Oates J, Gerstein M, Engelman DM, Dixon AM, Dimaio D. Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor. Journal of Virology. 83: 9773-85. PMID 19605488 DOI: 10.1128/Jvi.00946-09 |
0.352 |
|
| 2009 |
Kim JH, Hartley TL, Curran AR, Engelman DM. Molecular dynamics studies of the transmembrane domain of gp41 from HIV-1. Biochimica Et Biophysica Acta. 1788: 1804-12. PMID 19540828 DOI: 10.1016/J.Bbamem.2009.06.011 |
0.407 |
|
| 2009 |
V?vere AL, Biddlecombe GB, Spees WM, Garbow JR, Wijesinghe D, Andreev OA, Engelman DM, Reshetnyak YK, Lewis JS. A novel technology for the imaging of acidic prostate tumors by positron emission tomography. Cancer Research. 69: 4510-6. PMID 19417132 DOI: 10.1158/0008-5472.Can-08-3781 |
0.324 |
|
| 2009 |
Yao L, Zheng S, Engelman DM, Reshetnyak YK, Andreev OA. pHLIP-bionanosyringe for Targeting Acidic Solid Tumors and Selective Delivery of Nanomaterials Biophysical Journal. 96: 632a. DOI: 10.1016/J.Bpj.2008.12.3344 |
0.36 |
|
| 2009 |
Karabadzhak A, Weerakkody D, Engelman DM, Andreev OA, Reshetnyak YK. Kinetics Of Peptide (pHLIP) Insertion And Folding In A Lipid Bilayer Membrane Biophysical Journal. 96: 453a. DOI: 10.1016/J.Bpj.2008.12.2327 |
0.44 |
|
| 2008 |
Reshetnyak YK, Andreev OA, Segala M, Markin VS, Engelman DM. Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane. Proceedings of the National Academy of Sciences of the United States of America. 105: 15340-5. PMID 18829441 DOI: 10.1016/J.Bpj.2008.12.1836 |
0.447 |
|
| 2008 |
Zoonens M, Reshetnyak YK, Engelman DM. Bilayer interactions of pHLIP, a peptide that can deliver drugs and target tumors. Biophysical Journal. 95: 225-35. PMID 18359793 DOI: 10.1529/Biophysj.107.124156 |
0.473 |
|
| 2008 |
Dupuy AD, Engelman DM. Protein area occupancy at the center of the red blood cell membrane. Proceedings of the National Academy of Sciences of the United States of America. 105: 2848-52. PMID 18287056 DOI: 10.1073/Pnas.0712379105 |
0.807 |
|
| 2008 |
Gohon Y, Dahmane T, Ruigrok RW, Schuck P, Charvolin D, Rappaport F, Timmins P, Engelman DM, Tribet C, Popot JL, Ebel C. Bacteriorhodopsin/amphipol complexes: structural and functional properties. Biophysical Journal. 94: 3523-37. PMID 18192360 DOI: 10.1529/Biophysj.107.121848 |
0.375 |
|
| 2008 |
Yip KY, Patel P, Kim PM, Engelman DM, McDermott D, Gerstein M. An integrated system for studying residue coevolution in proteins. Bioinformatics (Oxford, England). 24: 290-2. PMID 18056067 DOI: 10.1093/Bioinformatics/Btm584 |
0.306 |
|
| 2007 |
Reshetnyak YK, Segala M, Andreev OA, Engelman DM. A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers. Biophysical Journal. 93: 2363-72. PMID 17557792 DOI: 10.1529/Biophysj.107.109967 |
0.45 |
|
| 2007 |
Andreev OA, Dupuy AD, Segala M, Sandugu S, Serra DA, Chichester CO, Engelman DM, Reshetnyak YK. Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 7893-8. PMID 17483464 DOI: 10.1073/Pnas.0702439104 |
0.806 |
|
| 2006 |
Matthews EE, Zoonens M, Engelman DM. Dynamic helix interactions in transmembrane signaling. Cell. 127: 447-50. PMID 17081964 DOI: 10.1016/J.Cell.2006.10.016 |
0.685 |
|
| 2006 |
Sachs JN, Engelman DM. Introduction to the membrane protein reviews: the interplay of structure, dynamics, and environment in membrane protein function. Annual Review of Biochemistry. 75: 707-12. PMID 16756508 DOI: 10.1146/Annurev.Biochem.75.110105.142336 |
0.409 |
|
| 2006 |
Miyauchi K, Curran R, Matthews E, Komano J, Hoshino T, Engelman DM, Matsuda Z. Mutations of conserved glycine residues within the membrane-spanning domain of human immunodeficiency virus type 1 gp41 can inhibit membrane fusion and incorporation of Env onto virions. Japanese Journal of Infectious Diseases. 59: 77-84. PMID 16632906 |
0.638 |
|
| 2006 |
Dixon AM, Stanley BJ, Matthews EE, Dawson JP, Engelman DM. Invariant chain transmembrane domain trimerization: a step in MHC class II assembly. Biochemistry. 45: 5228-34. PMID 16618111 DOI: 10.1021/Bi052112E |
0.757 |
|
| 2006 |
Reshetnyak YK, Andreev OA, Lehnert U, Engelman DM. Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix. Proceedings of the National Academy of Sciences of the United States of America. 103: 6460-5. PMID 16608910 DOI: 10.1073/Pnas.0601463103 |
0.376 |
|
| 2006 |
Finger C, Volkmer T, Prodöhl A, Otzen DE, Engelman DM, Schneider D. The stability of transmembrane helix interactions measured in a biological membrane. Journal of Molecular Biology. 358: 1221-8. PMID 16574146 DOI: 10.1016/J.Jmb.2006.02.065 |
0.478 |
|
| 2006 |
Engelman DM, Moore PB. Small‐angle neutron scattering International Tables For Crystallography. DOI: 10.1107/97809553602060000701 |
0.452 |
|
| 2005 |
Engelman DM. Membranes are more mosaic than fluid. Nature. 438: 578-80. PMID 16319876 DOI: 10.1038/Nature04394 |
0.428 |
|
| 2005 |
Chin CN, Sachs JN, Engelman DM. Transmembrane homodimerization of receptor-like protein tyrosine phosphatases. Febs Letters. 579: 3855-8. PMID 15978577 DOI: 10.1016/J.Febslet.2005.05.071 |
0.442 |
|
| 2005 |
Freeman-Cook LL, Edwards AP, Dixon AM, Yates KE, Ely L, Engelman DM, Dimaio D. Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor. Journal of Molecular Biology. 345: 907-21. PMID 15588835 DOI: 10.1016/J.Jmb.2004.10.072 |
0.34 |
|
| 2004 |
Lehnert U, Xia Y, Royce TE, Goh CS, Liu Y, Senes A, Yu H, Zhang ZL, Engelman DM, Gerstein M. Computational analysis of membrane proteins: genomic occurrence, structure prediction and helix interactions. Quarterly Reviews of Biophysics. 37: 121-46. PMID 15999419 DOI: 10.1017/S003358350400397X |
0.733 |
|
| 2004 |
Schneider D, Engelman DM. Motifs of two small residues can assist but are not sufficient to mediate transmembrane helix interactions. Journal of Molecular Biology. 343: 799-804. PMID 15476801 DOI: 10.1016/J.Jmb.2004.08.083 |
0.401 |
|
| 2004 |
Braun R, Engelman DM, Schulten K. Molecular Dynamics Simulations of Micelle Formation around Dimeric Glycophorin A Transmembrane Helices. Biophysical Journal. 87: 754-63. PMID 15298884 DOI: 10.1529/Biophysj.104.040279 |
0.386 |
|
| 2004 |
Freeman-Cook LL, Dixon AM, Frank JB, Xia Y, Ely L, Gerstein M, Engelman DM, DiMaio D. Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor. Journal of Molecular Biology. 338: 907-20. PMID 15111056 DOI: 10.1016/J.Jmb.2004.03.044 |
0.349 |
|
| 2004 |
Mitra K, Ubarretxena-Belandia I, Taguchi T, Warren G, Engelman DM. Modulation of the bilayer thickness of exocytic pathway membranes by membrane proteins rather than cholesterol. Proceedings of the National Academy of Sciences of the United States of America. 101: 4083-8. PMID 15016920 DOI: 10.1073/Pnas.0307332101 |
0.437 |
|
| 2004 |
Liu Y, Gerstein M, Engelman DM. Transmembrane protein domains rarely use covalent domain recombination as an evolutionary mechanism. Proceedings of the National Academy of Sciences of the United States of America. 101: 3495-7. PMID 14993608 DOI: 10.1073/Pnas.0307330101 |
0.428 |
|
| 2004 |
Melnyk RA, Kim S, Curran AR, Engelman DM, Bowie JU, Deber CM. The affinity of GXXXG motifs in transmembrane helix-helix interactions is modulated by long-range communication. The Journal of Biological Chemistry. 279: 16591-7. PMID 14766751 DOI: 10.1074/Jbc.M313936200 |
0.418 |
|
| 2003 |
Engelman DM, Chen Y, Chin CN, Curran AR, Dixon AM, Dupuy AD, Lee AS, Lehnert U, Matthews EE, Reshetnyak YK, Senes A, Popot JL. Membrane protein folding: beyond the two stage model. Febs Letters. 555: 122-5. PMID 14630331 DOI: 10.1016/S0014-5793(03)01106-2 |
0.797 |
|
| 2003 |
Fisher LE, Engelman DM, Sturgis JN. Effect of detergents on the association of the glycophorin a transmembrane helix. Biophysical Journal. 85: 3097-105. PMID 14581210 DOI: 10.1016/S0006-3495(03)74728-6 |
0.642 |
|
| 2003 |
Popot JL, Berry EA, Charvolin D, Creuzenet C, Ebel C, Engelman DM, Flötenmeyer M, Giusti F, Gohon Y, Hong Q, Lakey JH, Leonard K, Shuman HA, Timmins P, Warschawski DE, et al. Amphipols: polymeric surfactants for membrane biology research. Cellular and Molecular Life Sciences : Cmls. 60: 1559-74. PMID 14513831 DOI: 10.1007/S00018-003-3169-6 |
0.418 |
|
| 2003 |
Curran AR, Engelman DM. Sequence motifs, polar interactions and conformational changes in helical membrane proteins. Current Opinion in Structural Biology. 13: 412-7. PMID 12948770 DOI: 10.1016/S0959-440X(03)00102-7 |
0.453 |
|
| 2003 |
Constantinescu SN, Keren T, Russ WP, Ubarretxena-Belandia I, Malka Y, Kubatzky KF, Engelman DM, Lodish HF, Henis YI. The erythropoietin receptor transmembrane domain mediates complex formation with viral anemic and polycythemic gp55 proteins. The Journal of Biological Chemistry. 278: 43755-63. PMID 12930840 DOI: 10.1074/Jbc.M302974200 |
0.315 |
|
| 2003 |
Dawson JP, Melnyk RA, Deber CM, Engelman DM. Sequence context strongly modulates association of polar residues in transmembrane helices. Journal of Molecular Biology. 331: 255-62. PMID 12875850 DOI: 10.1016/S0022-2836(03)00714-9 |
0.702 |
|
| 2003 |
Engelman DM. Electrostatic fasteners hold the T cell receptor-CD3 complex together. Molecular Cell. 11: 5-6. PMID 12535514 DOI: 10.1016/S1097-2765(03)00016-9 |
0.336 |
|
| 2003 |
Schneider D, Engelman DM. GALLEX, a measurement of heterologous association of transmembrane helices in a biological membrane. The Journal of Biological Chemistry. 278: 3105-11. PMID 12446730 DOI: 10.1074/Jbc.M206287200 |
0.468 |
|
| 2002 |
Bowen ME, Engelman DM, Brunger AT. Mutational analysis of synaptobrevin transmembrane domain oligomerization. Biochemistry. 41: 15861-6. PMID 12501216 DOI: 10.1021/Bi0269411 |
0.456 |
|
| 2002 |
Schneider D, Liu Y, Gerstein M, Engelman DM. Thermostability of membrane protein helix-helix interaction elucidated by statistical analysis. Febs Letters. 532: 231-6. PMID 12459496 DOI: 10.1016/S0014-5793(02)03687-6 |
0.482 |
|
| 2002 |
Liu Y, Engelman DM, Gerstein M. Genomic analysis of membrane protein families: abundance and conserved motifs. Genome Biology. 3: research0054. PMID 12372142 DOI: 10.1186/Gb-2002-3-10-Research0054 |
0.393 |
|
| 2002 |
Mitra K, Steitz TA, Engelman DM. Rational design of 'water-soluble' bacteriorhodopsin variants. Protein Engineering. 15: 485-92. PMID 12082167 DOI: 10.1093/Protein/15.6.485 |
0.422 |
|
| 2002 |
Dawson JP, Weinger JS, Engelman DM. Motifs of serine and threonine can drive association of transmembrane helices. Journal of Molecular Biology. 316: 799-805. PMID 11866532 DOI: 10.1006/Jmbi.2001.5353 |
0.693 |
|
| 2001 |
Fleming KG, Engelman DM. Computation and mutagenesis suggest a right-handed structure for the synaptobrevin transmembrane dimer. Proteins. 45: 313-7. PMID 11746678 DOI: 10.1002/Prot.1151 |
0.641 |
|
| 2001 |
Fleming KG, Engelman DM. Specificity in transmembrane helix-helix interactions can define a hierarchy of stability for sequence variants. Proceedings of the National Academy of Sciences of the United States of America. 98: 14340-4. PMID 11724930 DOI: 10.1073/Pnas.251367498 |
0.664 |
|
| 2001 |
Leeds JA, Boyd D, Huber DR, Sonoda GK, Luu HT, Engelman DM, Beckwith J. Genetic selection for and molecular dynamic modeling of a protein transmembrane domain multimerization motif from a random Escherichia coli genomic library. Journal of Molecular Biology. 313: 181-95. PMID 11601855 DOI: 10.1006/Jmbi.2001.5007 |
0.78 |
|
| 2001 |
Senes A, Ubarretxena-Belandia I, Engelman DM. The Calpha ---H...O hydrogen bond: a determinant of stability and specificity in transmembrane helix interactions. Proceedings of the National Academy of Sciences of the United States of America. 98: 9056-61. PMID 11481472 DOI: 10.1073/Pnas.161280798 |
0.66 |
|
| 2001 |
Ubarretxena-Belandia I, Engelman DM. Helical membrane proteins: diversity of functions in the context of simple architecture. Current Opinion in Structural Biology. 11: 370-6. PMID 11406389 DOI: 10.1016/S0959-440X(00)00217-7 |
0.461 |
|
| 2001 |
Li H, Cocco MJ, Steitz TA, Engelman DM. Conversion of phospholamban into a soluble pentameric helical bundle. Biochemistry. 40: 6636-45. PMID 11380258 DOI: 10.1021/Bi0026573 |
0.484 |
|
| 2001 |
Fisher LE, Engelman DM. High-yield synthesis and purification of an alpha-helical transmembrane domain. Analytical Biochemistry. 293: 102-8. PMID 11373085 DOI: 10.1006/Abio.2001.5122 |
0.633 |
|
| 2001 |
Zhou FX, Merianos HJ, Brunger AT, Engelman DM. Polar residues drive association of polyleucine transmembrane helices. Proceedings of the National Academy of Sciences of the United States of America. 98: 2250-5. PMID 11226225 DOI: 10.1073/Pnas.041593698 |
0.535 |
|
| 2000 |
Petrache HI, Grossfield A, MacKenzie KR, Engelman DM, Woolf TB. Modulation of glycophorin A transmembrane helix interactions by lipid bilayers: molecular dynamics calculations. Journal of Molecular Biology. 302: 727-46. PMID 10986130 DOI: 10.1006/Jmbi.2000.4072 |
0.428 |
|
| 2000 |
Popot JL, Engelman DM. Helical membrane protein folding, stability, and evolution. Annual Review of Biochemistry. 69: 881-922. PMID 10966478 DOI: 10.1146/Annurev.Biochem.69.1.881 |
0.458 |
|
| 2000 |
Senes A, Gerstein M, Engelman DM. Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions. Journal of Molecular Biology. 296: 921-36. PMID 10677292 DOI: 10.1006/Jmbi.1999.3488 |
0.692 |
|
| 2000 |
Russ WP, Engelman DM. The GxxxG motif: a framework for transmembrane helix-helix association. Journal of Molecular Biology. 296: 911-9. PMID 10677291 DOI: 10.1006/Jmbi.1999.3489 |
0.385 |
|
| 2000 |
Zhou FX, Cocco MJ, Russ WP, Brunger AT, Engelman DM. Interhelical hydrogen bonding drives strong interactions in membrane proteins. Nature Structural Biology. 7: 154-60. PMID 10655619 DOI: 10.1038/72430 |
0.58 |
|
| 1999 |
Fisher LE, Engelman DM, Sturgis JN. Detergents modulate dimerization, but not helicity, of the glycophorin A transmembrane domain. Journal of Molecular Biology. 293: 639-51. PMID 10543956 DOI: 10.1006/Jmbi.1999.3126 |
0.655 |
|
| 1999 |
McNew JA, Weber T, Engelman DM, Söllner TH, Rothman JE. The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion. Molecular Cell. 4: 415-21. PMID 10518222 DOI: 10.1016/S1097-2765(00)80343-3 |
0.428 |
|
| 1999 |
Bu Z, Engelman DM. A method for determining transmembrane helix association and orientation in detergent micelles using small angle x-ray scattering. Biophysical Journal. 77: 1064-73. PMID 10423450 DOI: 10.1016/S0006-3495(99)76956-0 |
0.363 |
|
| 1999 |
Schubert C, Hirsch JA, Gurevich VV, Engelman DM, Sigler PB, Fleming KG. Visual arrestin activity may be regulated by self-association. The Journal of Biological Chemistry. 274: 21186-90. PMID 10409673 DOI: 10.1074/Jbc.274.30.21186 |
0.6 |
|
| 1999 |
Koide S, Bu Z, Risal D, Pham TN, Nakagawa T, Tamura A, Engelman DM. Multistep denaturation of Borrelia burgdorferi OspA, a protein containing a single-layer beta-sheet. Biochemistry. 38: 4757-67. PMID 10200164 DOI: 10.1021/Bi982443+ |
0.332 |
|
| 1999 |
Russ WP, Engelman DM. TOXCAT: a measure of transmembrane helix association in a biological membrane. Proceedings of the National Academy of Sciences of the United States of America. 96: 863-8. PMID 9927659 DOI: 10.1073/Pnas.96.3.863 |
0.489 |
|
| 1998 |
Adams PD, Lee AS, Brünger AT, Engelman DM. Models for the transmembrane region of the phospholamban pentamer: which is correct? Annals of the New York Academy of Sciences. 853: 178-85. PMID 10603945 DOI: 10.1111/J.1749-6632.1998.Tb08265.X |
0.436 |
|
| 1998 |
MacKenzie KR, Engelman DM. Structure-based prediction of the stability of transmembrane helix-helix interactions: the sequence dependence of glycophorin A dimerization. Proceedings of the National Academy of Sciences of the United States of America. 95: 3583-90. PMID 9520409 DOI: 10.1073/Pnas.95.7.3583 |
0.448 |
|
| 1998 |
Fleming KG, Ackerman AL, Engelman DM. Free energy measurements of transmembrane helix-helix interactions Chemtracts. 11: 985-990. |
0.548 |
|
| 1997 |
Hunt JF, Rath P, Rothschild KJ, Engelman DM. Spontaneous, pH-dependent membrane insertion of a transbilayer alpha-helix. Biochemistry. 36: 15177-92. PMID 9398245 DOI: 10.1021/Bi970147B |
0.496 |
|
| 1997 |
Hunt JF, Earnest TN, Bousché O, Kalghatgi K, Reilly K, Horváth C, Rothschild KJ, Engelman DM. A biophysical study of integral membrane protein folding. Biochemistry. 36: 15156-76. PMID 9398244 DOI: 10.1021/Bi970146J |
0.465 |
|
| 1997 |
Hunt JF, McCrea PD, Zaccaï G, Engelman DM. Assessment of the aggregation state of integral membrane proteins in reconstituted phospholipid vesicles using small angle neutron scattering. Journal of Molecular Biology. 273: 1004-19. PMID 9367787 DOI: 10.1006/Jmbi.1997.1330 |
0.421 |
|
| 1997 |
Fleming KG, Ackerman AL, Engelman DM. The effect of point mutations on the free energy of transmembrane alpha-helix dimerization. Journal of Molecular Biology. 272: 266-75. PMID 9299353 DOI: 10.1006/Jmbi.1997.1236 |
0.645 |
|
| 1997 |
Arkin IT, Brünger AT, Engelman DM. Are there dominant membrane protein families with a given number of helices? Proteins. 28: 465-6. PMID 9261863 DOI: 10.1002/(Sici)1097-0134(199708)28:4<465::Aid-Prot1>3.0.Co;2-9 |
0.393 |
|
| 1997 |
Arkin IT, Adams PD, Brünger AT, Smith SO, Engelman DM. Structural perspectives of phospholamban, a helical transmembrane pentamer. Annual Review of Biophysics and Biomolecular Structure. 26: 157-79. PMID 9241417 DOI: 10.1146/Annurev.Biophys.26.1.157 |
0.374 |
|
| 1997 |
MacKenzie KR, Prestegard JH, Engelman DM. A transmembrane helix dimer: structure and implications. Science (New York, N.Y.). 276: 131-3. PMID 9082985 DOI: 10.1126/Science.276.5309.131 |
0.437 |
|
| 1997 |
Arkin IT, Adams PD, Brünger AT, Aimoto S, Engelman DM, Smith SO. Structure of the transmembrane cysteine residues in phospholamban. The Journal of Membrane Biology. 155: 199-206. PMID 9050443 DOI: 10.1007/S002329900172 |
0.437 |
|
| 1997 |
Burke CL, Lemmon MA, Coren BA, Engelman DM, Stern DF. Dimerization of the p185neu transmembrane domain is necessary but not sufficient for transformation. Oncogene. 14: 687-96. PMID 9038376 DOI: 10.1038/Sj.Onc.1200873 |
0.573 |
|
| 1997 |
Lemmon MA, Bu Z, Ladbury JE, Zhou M, Pinchasi D, Lax I, Engelman DM, Schlessinger J. Two EGF molecules contribute additively to stabilization of the EGFR dimer. The Embo Journal. 16: 281-94. PMID 9029149 DOI: 10.1093/Emboj/16.2.281 |
0.624 |
|
| 1996 |
Engelman DM. Crossing the hydrophobic barrier: insertion of membrane proteins. Science (New York, N.Y.). 274: 1850-1. PMID 8984645 DOI: 10.1126/Science.274.5294.1850 |
0.405 |
|
| 1996 |
Adams PD, Engelman DM, Brünger AT. Improved prediction for the structure of the dimeric transmembrane domain of glycophorin A obtained through global searching. Proteins. 26: 257-61. PMID 8953647 DOI: 10.1002/(Sici)1097-0134(199611)26:3<257::Aid-Prot2>3.0.Co;2-B |
0.356 |
|
| 1996 |
Smith CK, Bu Z, Anderson KS, Sturtevant JM, Engelman DM, Regan L. Surface point mutations that significantly alter the structure and stability of a protein's denatured state. Protein Science : a Publication of the Protein Society. 5: 2009-19. PMID 8897601 DOI: 10.1002/Pro.5560051007 |
0.303 |
|
| 1996 |
MacKenzie KR, Prestegard JH, Engelman DM. Leucine side-chain rotamers in a glycophorin A transmembrane peptide as revealed by three-bond carbon-carbon couplings and 13C chemical shifts. Journal of Biomolecular Nmr. 7: 256-60. PMID 8785502 DOI: 10.1007/Bf00202043 |
0.318 |
|
| 1996 |
Ludlam CF, Arkin IT, Liu XM, Rothman MS, Rath P, Aimoto S, Smith SO, Engelman DM, Rothschild KJ. Fourier transform infrared spectroscopy and site-directed isotope labeling as a probe of local secondary structure in the transmembrane domain of phospholamban. Biophysical Journal. 70: 1728-36. PMID 8785331 DOI: 10.1016/S0006-3495(96)79735-7 |
0.455 |
|
| 1996 |
Rodgers KK, Bu Z, Fleming KG, Schatz DG, Engelman DM, Coleman JE. A zinc-binding domain involved in the dimerization of RAG1. Journal of Molecular Biology. 260: 70-84. PMID 8676393 DOI: 10.1006/Jmbi.1996.0382 |
0.626 |
|
| 1996 |
Peled-Zehavi H, Arkin IT, Engelman DM, Shai Y. Coassembly of synthetic segments of shaker K+ channel within phospholipid membranes. Biochemistry. 35: 6828-38. PMID 8639634 DOI: 10.1021/Bi952988T |
0.419 |
|
| 1996 |
Arkin IT, MacKenzie KR, Fisher L, Aimoto S, Engelman DM, Smith SO. Mapping the lipid-exposed surfaces of membrane proteins. Nature Structural Biology. 3: 240-3. PMID 8605625 DOI: 10.1038/Nsb0396-240 |
0.7 |
|
| 1995 |
Hare BJ, Prestegard JH, Engelman DM. Small angle x-ray scattering studies of magnetically oriented lipid bilayers. Biophysical Journal. 69: 1891-6. PMID 8580332 DOI: 10.1016/S0006-3495(95)80059-7 |
0.344 |
|
| 1995 |
Arkin IT, Rothman M, Ludlam CF, Aimoto S, Engelman DM, Rothschild KJ, Smith SO. Structural model of the phospholamban ion channel complex in phospholipid membranes. Journal of Molecular Biology. 248: 824-34. PMID 7752243 DOI: 10.1006/Jmbi.1995.0263 |
0.479 |
|
| 1995 |
Adams PD, Arkin IT, Engelman DM, Brünger AT. Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban. Nature Structural Biology. 2: 154-62. PMID 7749920 DOI: 10.1038/Nsb0295-154 |
0.347 |
|
| 1994 |
Lemmon MA, Engelman DM. Specificity and promiscuity in membrane helix interactions. Febs Letters. 346: 17-20. PMID 8206151 DOI: 10.1016/0014-5793(94)00467-6 |
0.656 |
|
| 1994 |
Adair BD, Engelman DM. Glycophorin A helical transmembrane domains dimerize in phospholipid bilayers: a resonance energy transfer study. Biochemistry. 33: 5539-44. PMID 8180176 DOI: 10.1021/Bi00184A024 |
0.384 |
|
| 1994 |
Samatey FA, Zaccaï G, Engelman DM, Etchebest C, Popot JL. Rotational orientation of transmembrane α-helices in bacteriorhodopsin. A neutron diffraction study Journal of Molecular Biology. 236: 1093-1104. PMID 8120889 DOI: 10.1016/0022-2836(94)90014-0 |
0.358 |
|
| 1994 |
Lemmon MA, Engelman DM. Specificity and promiscuity in membrane helix interactions. Quarterly Reviews of Biophysics. 27: 157-218. PMID 7984776 DOI: 10.1017/S0033583500004522 |
0.683 |
|
| 1994 |
Lemmon MA, Treutlein HR, Adams PD, Brünger AT, Engelman DM. A dimerization motif for transmembrane alpha-helices. Nature Structural Biology. 1: 157-63. PMID 7656033 DOI: 10.1038/Nsb0394-157 |
0.663 |
|
| 1994 |
Arkin IT, Adams PD, MacKenzie KR, Lemmon MA, Brünger AT, Engelman DM. Structural organization of the pentameric transmembrane alpha-helices of phospholamban, a cardiac ion channel. The Embo Journal. 13: 4757-64. PMID 7525269 DOI: 10.1002/J.1460-2075.1994.Tb06801.X |
0.638 |
|
| 1993 |
Engelman DM, Adair BD, Brünger A, Flanagan JM, Hunt JF, Lemmon MA, Treutlein H, Zhang J. Dimerization of glycophorin A transmembrane helices: mutagenesis and modeling. Society of General Physiologists Series. 48: 11-21. PMID 8503039 |
0.54 |
|
| 1993 |
Flanagan JM, Kataoka M, Fujisawa T, Engelman DM. Mutations can cause large changes in the conformation of a denatured protein Biochemistry. 32: 10359-10370. PMID 8399179 DOI: 10.1021/Bi00090A011 |
0.347 |
|
| 1993 |
Engelman DM, Adair BD, Brunger A, Flanagan JM, Hunt JF, Lemmon MA, Treutlein H, Zhang J. Dimerization of glycophorin A transmembrane helices: Mutagenesis and modeling Journal of General Physiology. 101: 11-21. DOI: 10.1007/978-94-011-2718-9_11 |
0.62 |
|
| 1992 |
Flanagan JM, Kataoka M, Shortle D, Engelman DM. Truncated staphylococcal nuclease is compact but disordered Proceedings of the National Academy of Sciences of the United States of America. 89: 748-752. PMID 1731350 DOI: 10.1073/Pnas.89.2.748 |
0.36 |
|
| 1992 |
Kahn TW, Engelman DM. Bacteriorhodopsin can be refolded from two independently stable transmembrane helices and the complementary five-helix fragment Biochemistry. 31: 6144-6151. PMID 1627558 DOI: 10.1021/Bi00141A027 |
0.399 |
|
| 1992 |
Lemmon MA, Flanagan JM, Hunt JF, Adair BD, Bormann BJ, Dempsey CE, Engelman DM. Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices. The Journal of Biological Chemistry. 267: 7683-9. PMID 1560003 |
0.593 |
|
| 1992 |
Kataoka M, Kahn TW, Tsujiuchi Y, Engelman DM, Tokunaga F. Bacteriorhodopsin reconstituted from two individual helices and the complementary five-helix fragment is photoactive Photochemistry and Photobiology. 56: 895-901. PMID 1492135 DOI: 10.1111/J.1751-1097.1992.Tb09710.X |
0.328 |
|
| 1992 |
Cramer WA, Engelman DM, Von Heijne G, Rees DC. Forces involved in the assembly and stabilization of membrane proteins Faseb Journal. 6: 3397-3402. PMID 1464373 DOI: 10.1096/Fasebj.6.15.1464373 |
0.497 |
|
| 1992 |
Treutlein HR, Lemmon MA, Engelman DM, Brünger AT. The glycophorin A transmembrane domain dimer: sequence-specific propensity for a right-handed supercoil of helices. Biochemistry. 31: 12726-32. PMID 1463744 DOI: 10.1021/Bi00166A003 |
0.591 |
|
| 1992 |
Lemmon MA, Flanagan JM, Treutlein HR, Zhang J, Engelman DM. Sequence specificity in the dimerization of transmembrane α-helices Biochemistry. 31: 12719-12725. PMID 1463743 DOI: 10.1021/Bi00166A002 |
0.657 |
|
| 1992 |
Kahn TW, Sturtevant JM, Engelman DM. Thermodynamic measurements of the contributions of helix-connecting loops and of retinal to the stability of bacteriorhodopsin. Biochemistry. 31: 8829-39. PMID 1390670 DOI: 10.1021/Bi00152A020 |
0.361 |
|
| 1992 |
Bormann BJ, Engelman DM. Intramembrane helix-helix association in oligomerization and transmembrane signaling Annual Review of Biophysics and Biomolecular Structure. 21: 223-242. PMID 1326354 DOI: 10.1146/Annurev.Bb.21.060192.001255 |
0.408 |
|
| 1992 |
Lemmon MA, Engelman DM. Helix-helix interactions inside lipid bilayers Current Opinion in Structural Biology. 2: 511-518. DOI: 10.1016/0959-440X(92)90080-Q |
0.647 |
|
| 1991 |
McCrea PD, Engelman DM, Popot JL. Topography of integral membrane proteins: hydrophobicity analysis vs. immunolocalization. Trends in Biochemical Sciences. 13: 289-90. PMID 3154280 DOI: 10.1016/0968-0004(88)90120-X |
0.311 |
|
| 1991 |
Kataoka M, Head JF, Persechini A, Kretsinger RH, Engelman DM. Small-angle X-ray scattering studies of calmodulin mutants with deletions in the linker region of the central helix indicate that the linker region retains a predominantly alpha-helical conformation. Biochemistry. 30: 1188-92. PMID 1991098 DOI: 10.1021/Bi00219A004 |
0.356 |
|
| 1990 |
Popot JL, Engelman DM, Zaccai G, de Vitry C. The "microassembly" of integral membrane proteins: applications & implications Progress in Clinical and Biological Research. 343: 237-262. PMID 2198582 |
0.386 |
|
| 1990 |
Popot JL, Engelman DM. Membrane protein folding and oligomerization: The two-stage model Biochemistry. 29: 4031-4037. PMID 1694455 DOI: 10.1021/Bi00469A001 |
0.465 |
|
| 1990 |
Engelman DM, Adair BD, Hunt JF, Kahn TW, Popot JL. Chapter 6 Bacteriorhodopsin Folding in Membranes: A Two-Stage Process Current Topics in Membranes and Transport. 36: 71-78. DOI: 10.1016/S0070-2161(08)60168-9 |
0.412 |
|
| 1989 |
Popot JL, Engelman DM, Gurel O, Zaccaï G. Tertiary structure of bacteriorhodopsin. Positions and orientations of helices A and B in the structural map determined by neutron diffraction Journal of Molecular Biology. 210: 829-847. PMID 2614846 DOI: 10.1016/0022-2836(89)90111-3 |
0.401 |
|
| 1988 |
Capel MS, Kjeldgaard M, Engelman DM, Moore PB. Positions of S2, S13, S16, S17, S19 and S21 in the 30 S ribosomal subunit of Escherichia coli. Journal of Molecular Biology. 200: 65-87. PMID 3288761 DOI: 10.1016/0022-2836(88)90334-8 |
0.469 |
|
| 1988 |
Capel M, Engelman D, Freeborn B, Kjeldgaard M, Langer J, Ramakrishnan V, Schindler D, Schneider D, Schoenborn B, Sillers I, Yabuki S, Moore P. A complete mapping of the positions of the proteins in the small ribosomal subunit of escherichia coli Makromolekulare Chemie. Macromolecular Symposia. 15: 123-130. DOI: 10.1002/Masy.19880150109 |
0.49 |
|
| 1987 |
Popot JL, Gerchman SE, Engelman DM. Refolding of bacteriorhodopsin in lipid bilayers. A thermodynamically controlled two-stage process Journal of Molecular Biology. 198: 655-676. PMID 3430624 DOI: 10.1016/0022-2836(87)90208-7 |
0.41 |
|
| 1987 |
McCrea PD, Popot JL, Engelman DM. Transmembrane topography of the nicotinic acetylcholine receptor delta subunit Embo Journal. 6: 3619-3626. PMID 3428268 DOI: 10.1002/J.1460-2075.1987.Tb02693.X |
0.349 |
|
| 1987 |
Capel MS, Engelman DM, Freeborn BR, Kjeldgaard M, Langer JA, Ramakrishnan V, Schindler DG, Schneider DK, Schoenborn BP, Sillers IY. A complete mapping of the proteins in the small ribosomal subunit of Escherichia coli. Science (New York, N.Y.). 238: 1403-6. PMID 3317832 DOI: 10.1126/Science.3317832 |
0.301 |
|
| 1986 |
Moore PB, Capel M, Kjeldgaard M, Engelman DM. Quaternary Organization of the 30S Ribosomal Subunit of Escherichia Coli. Biophysical Journal. 49: 13-5. PMID 19431616 DOI: 10.1016/S0006-3495(86)83573-1 |
0.432 |
|
| 1986 |
Trewhella J, Popot JL, Zaccaï G, Engelman DM. Localization of two chymotryptic fragments in the structure of renatured bacteriorhodopsin by neutron diffraction. The Embo Journal. 5: 3045-9. PMID 3792306 DOI: 10.1002/J.1460-2075.1986.Tb04604.X |
0.616 |
|
| 1986 |
Popot JL, Trewhella J, Engelman DM. Reformation of crystalline purple membrane from purified bacteriorhodopsin fragments. The Embo Journal. 5: 3039-44. PMID 3792305 DOI: 10.1002/J.1460-2075.1986.Tb04603.X |
0.623 |
|
| 1986 |
Engelman DM, Steitz TA, Goldman A. Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteins Annual Review of Biophysics and Biophysical Chemistry. 15: 321-353. PMID 3521657 DOI: 10.1146/annurev.bb.15.060186.001541 |
0.307 |
|
| 1986 |
Trewhella J, Popot JL, Engelman DM, Zaccai G. Neutron diffraction studies of bacteriorhodopsin Physica B+C. 136: 249-251. DOI: 10.1016/S0378-4363(86)80067-5 |
0.506 |
|
| 1985 |
Dumont ME, Trewhella J, Engelman DM, Richards FM. Stability of transmembrane regions in bacteriorhodopsin studied by progressive proteolysis. The Journal of Membrane Biology. 88: 233-47. PMID 3913776 DOI: 10.1007/Bf01871088 |
0.648 |
|
| 1984 |
Gogol EP, Engelman DM. Neutron scattering shows that cytochrome b5 penetrates deeply into the lipid bilayer Biophysical Journal. 46: 491-495. PMID 6498267 DOI: 10.1016/S0006-3495(84)84046-1 |
0.351 |
|
| 1984 |
Ramakrishnan V, Capel M, Kjeldgaard M, Engelman DM, Moore PB. Positions of proteins S14, S18 and S20 in the 30 S ribosomal subunit of Escherichia coli. Journal of Molecular Biology. 174: 265-84. PMID 6371250 DOI: 10.1016/0022-2836(84)90338-3 |
0.443 |
|
| 1984 |
Moore PB, Engelman DM, Langer JA, Ramakrishnan VR, Schindler DG, Schoenborn BP, Sillers IY, Yabuki S. Neutron scattering and the 30 S ribosomal subunit of E. coli. Basic Life Sciences. 27: 73-91. PMID 6370225 DOI: 10.1007/978-1-4899-0375-4_4 |
0.464 |
|
| 1983 |
Trewhella J, Anderson S, Fox R, Gogol E, Khan S, Engelman D, Zaccai G. Assignment of segments of the bacteriorhodopsin sequence to positions in the structural map Biophysical Journal. 42: 233-241. PMID 6871370 DOI: 10.1016/S0006-3495(83)84391-4 |
0.596 |
|
| 1983 |
Lewis BA, Engelman DM. Lipid bilayer thickness varies linearly with acyl chain length in fluid phosphatidylcholine vesicles Journal of Molecular Biology. 166: 211-217. PMID 6854644 DOI: 10.1016/S0022-2836(83)80007-2 |
0.303 |
|
| 1983 |
Lewis BA, Engelman DM. Bacteriorhodopsin remains dispersed in fluid phospholipid bilayers over a wide range of bilayer thicknesses Journal of Molecular Biology. 166: 203-210. PMID 6854643 DOI: 10.1016/S0022-2836(83)80006-0 |
0.387 |
|
| 1983 |
Gogol EP, Engelman DM, Zaccai G. Neutron diffraction analysis of cytochrome b5 reconstituted in deuterated lipid multilayers Biophysical Journal. 43: 285-292. PMID 6626669 DOI: 10.1016/S0006-3495(83)84352-5 |
0.411 |
|
| 1983 |
Pearson LT, Chan SI, Lewis BA, Engelman DM. Pair distribution functions of bacteriorhodopsin and rhodopsin in model bilayers. Biophysical Journal. 43: 167-74. PMID 6616005 DOI: 10.1016/S0006-3495(83)84337-9 |
0.323 |
|
| 1982 |
Engelman DM, Goldman A, Steitz TA. [11] The identification of helical segments in the polypeptide chain of bacteriorhodopsin Methods in Enzymology. 88: 81-88. DOI: 10.1016/0076-6879(82)88014-2 |
0.428 |
|
| 1981 |
Engelman DM, Steitz TA. The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis Cell. 23: 411-422. PMID 7471207 DOI: 10.1016/0092-8674(81)90136-7 |
0.492 |
|
| 1981 |
Goodsaid-Zalduondo F, Engelman DM. Conformation of liquid N-alkanes Biophysical Journal. 35: 587-594. PMID 7272453 DOI: 10.1016/S0006-3495(81)84814-X |
0.382 |
|
| 1981 |
Ramakrishnan VR, Yabuki S, Sillers IY, Schindler DG, Engelman DM, Moore PB. Positions of proteins S6, S11 and S15 in the 30 S ribosomal subunit of Escherichia coli. Journal of Molecular Biology. 153: 739-60. PMID 7040690 DOI: 10.1016/0022-2836(81)90416-2 |
0.462 |
|
| 1981 |
Burks C, Engelman DM. Cholesteryl myristate conformation in liquid crystalline mesophases determined by neutron scattering Proceedings of the National Academy of Sciences of the United States of America. 78: 6863-6867. PMID 6947261 DOI: 10.1073/Pnas.78.11.6863 |
0.339 |
|
| 1980 |
Yeager M, Schoenborn B, Engelman D, Moore P, Stryer L. Neutron diffraction analysis of the structure of rod photoreceptor membranes in intact retinas. Journal of Molecular Biology. 137: 315-48. PMID 6973637 DOI: 10.1016/0022-2836(80)90319-8 |
0.519 |
|
| 1980 |
Engelman DM, Zaccai G. Bacteriorhodopsin is an inside-out protein Proceedings of the National Academy of Sciences of the United States of America. 77: 5894-5898. PMID 6934521 DOI: 10.1073/Pnas.77.10.5894 |
0.416 |
|
| 1979 |
Schindler DG, Langer JA, Engelman DM, Moore PB. Positions of proteins S10, S11 and S12 in the 30 S ribosomal subunit of Escherichia coli. Journal of Molecular Biology. 134: 595-620. PMID 395318 DOI: 10.1016/0022-2836(79)90369-3 |
0.46 |
|
| 1979 |
Moore PB, Engelman DM. [49] On the feasibility and interpretation of intersubunit distance measurements using neutron scattering Methods in Enzymology. 59: 629-638. DOI: 10.1016/0076-6879(79)59118-6 |
0.456 |
|
| 1978 |
Wallace BA, Engelman DM. The planar distributions of surface proteins and intramembrane particles in Acholeplasma laidlawii are differentially affected by the physical state of membrane lipids Bba - Biomembranes. 508: 431-449. PMID 638151 DOI: 10.1016/0005-2736(78)90090-1 |
0.402 |
|
| 1978 |
Laughrea M, Engelman DM, Moore PB. X-ray and neutron small-angle scattering studies of the complex between protein S1 and the 30-S ribosomal subunit European Journal of Biochemistry. 85: 529-534. PMID 348475 DOI: 10.1111/J.1432-1033.1978.Tb12268.X |
0.72 |
|
| 1978 |
Langer JA, Engelman DM, Moore PB. Neutron-scattering studies of the ribosome of Escherichia coli: a provisional map of the locations of proteins S3, S4, S5, S7, S8 and S9 in the 30 S subunit. Journal of Molecular Biology. 119: 463-85. PMID 347087 DOI: 10.1016/0022-2836(78)90197-3 |
0.468 |
|
| 1978 |
Moore PB, Langer JA, Engelman DM. The measurement of the locations and radii of gyration of proteins in the 30S ribosomal subunit ofE. coliby neutron scattering Journal of Applied Crystallography. 11: 479-482. DOI: 10.1107/S0021889878013643 |
0.476 |
|
| 1977 |
Moore PB, Engelman DM. Model calculations of protein pair interference functions Journal of Molecular Biology. 112: 228-234. PMID 875017 DOI: 10.1016/S0022-2836(77)80140-X |
0.478 |
|
| 1977 |
Moore PB, Langer JA, Schoenborn BP, Engelman DM. Triangulation of proteins in the 30 S ribosomal subunit of Exherichia coli. Journal of Molecular Biology. 112: 199-227. PMID 327074 DOI: 10.1016/S0022-2836(77)80139-3 |
0.443 |
|
| 1976 |
Wallace BA, Richards FM, Engelman DM. The influence of lipid state on the planar distribution of membrane proteins in Acholeplasma laidlawii Journal of Molecular Biology. 107: 255-269. PMID 1003469 DOI: 10.1016/S0022-2836(76)80004-6 |
0.399 |
|
| 1976 |
Engelman DM, Moore PB. Neutron-scattering studies of the ribosome Scientific American. 235: 44-54. PMID 968478 DOI: 10.1038/Scientificamerican1076-44 |
0.436 |
|
| 1975 |
Engelman DM, Moore PB, Schoenborn BP. Neutron scattering measurements of separation and shape of proteins in 30S ribosomal subunit of Escherichia coli:S2-S5, S5-S8, S3-S7 Proceedings of the National Academy of Sciences of the United States of America. 72: 3888-3892. PMID 1105567 DOI: 10.1073/Pnas.72.10.3888 |
0.48 |
|
| 1975 |
Moore PB, Engelman DM, Schoenborn BP. A neutron scattering study of the distribution of protein and RNA in the 30 S ribosomal subunit of Escherichia coli Journal of Molecular Biology. 91: 101-120. PMID 1102695 DOI: 10.1016/0022-2836(75)90374-5 |
0.46 |
|
| 1974 |
Steitz TA, Richmond TJ, Wise D, Engelman D. The lac repressor protein: molecular shape, subunit structure, and proposed model for operator interaction based on structural studies of microcrystals. Proceedings of the National Academy of Sciences of the United States of America. 71: 593-7. PMID 4595565 DOI: 10.1073/Pnas.71.3.593 |
0.311 |
|
| 1974 |
Moore PB, Engelman DM, Schoenborn BP. Asymmetry in the 50S ribosomal subunit of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 71: 172-176. PMID 4589891 DOI: 10.1073/Pnas.71.1.172 |
0.483 |
|
| 1972 |
Metcalfe SM, Metcalfe JC, Engelman DM. Structural comparisons of native and reaggregated membranes from Mycoplasma laidawii and erythrocytes using a fluorescence probe. Biochimica Et Biophysica Acta. 241: 422-30. PMID 5159792 DOI: 10.1016/0005-2736(71)90042-3 |
0.402 |
|
| 1972 |
Metcalfe JC, Metcalfe SM, Engelman DM. Structural comparisons of native and reaggregated membranes from Mycoplasma laidlawii and erythrocytes by x-ray diffraction and nuclear magnetic resonance techniques. Biochimica Et Biophysica Acta. 241: 412-21. PMID 5159791 DOI: 10.1016/0005-2736(71)90041-1 |
0.445 |
|
| 1972 |
Engelman DM. The molecular structure of the membrane of Acholeplasma laidlawii Chemistry and Physics of Lipids. 8: 298-302. PMID 5041943 DOI: 10.1016/0009-3084(72)90058-8 |
0.426 |
|
| 1972 |
Engelman DM, Moore PB. A new method for the determination of biological quarternary structure by neutron scattering Proceedings of the National Academy of Sciences of the United States of America. 69: 1997-1999. PMID 4506067 DOI: 10.1073/Pnas.69.8.1997 |
0.474 |
|
| 1972 |
Rothman JE, Engelman DM. Molecular mechanism for the interaction of phospholipid with cholesterol Nature: New Biology. 237: 42-44. PMID 4503742 DOI: 10.1038/Newbio237042A0 |
0.312 |
|
| 1971 |
Wilkins MH, Blaurock AE, Engelman DM. Bilayer structure in membranes. Nature: New Biology. 230: 72-6. PMID 5279041 DOI: 10.1038/Newbio230072A0 |
0.797 |
|
| 1971 |
Engelman DM. Lipid bilayer structure in the membrane of Mycoplasma laidlawii. Journal of Molecular Biology. 58: 153-65. PMID 5088924 DOI: 10.1016/0022-2836(71)90238-5 |
0.421 |
|
| 1970 |
Engelman DM. X-ray diffraction studies of phase transitions in the membrane of Mycoplasma laidlawii. Journal of Molecular Biology. 47: 115-7. PMID 5413340 DOI: 10.1016/0022-2836(70)90407-9 |
0.355 |
|
| 1969 |
Engelman DM. Surface Area per Lipid Molecule in the Intact Membrane of the Human Red Cell Nature. 223: 1279-1280. PMID 5811911 DOI: 10.1038/2231279A0 |
0.367 |
|
| 1969 |
Stoeckenius W, Engelman DM. Current models for the structure of biological membranes. The Journal of Cell Biology. 42: 613-46. PMID 4895596 DOI: 10.1083/Jcb.42.3.613 |
0.636 |
|
| 1968 |
Engelman DM, Morowitz HJ. Characterization of the plasma membrane of Mycoplasma laidlawii. IV. Structure and composition of membrane and aggregated components. Biochimica Et Biophysica Acta. 150: 385-96. PMID 5650391 DOI: 10.1016/0005-2736(68)90137-5 |
0.565 |
|
| 1968 |
Engelman DM, Morowitz HJ. Characterization of the plasma membrane of Mycoplasma laidlawii. 3. The formation and aggregation of small lipoprotein structures derived from sodium dodecyl sulfate-solubilized membrane components. Biochimica Et Biophysica Acta. 150: 376-84. PMID 5650390 DOI: 10.1016/0005-2736(68)90136-3 |
0.587 |
|
| 1967 |
Terry TM, Engelman DM, Morowitz HJ. Characterization of the plasma membrane of Mycoplasma laidlawii. II. Modes of aggregation of solubilized membrane components. Biochimica Et Biophysica Acta. 135: 391-405. PMID 6058126 DOI: 10.1016/0005-2736(67)90029-6 |
0.53 |
|
| 1967 |
Engelman DM, Terry TM, Morowitz HJ. Characterization of the plasma membrane of Mycoplasma laidlawii. I. Sodium dodecyl sulfate solubilization. Biochimica Et Biophysica Acta. 135: 381-90. PMID 6048810 DOI: 10.1016/0005-2736(67)90028-4 |
0.591 |
|
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