Tooru M. Mizuno - Publications

Affiliations: 
Physiology University of Manitoba, Winnipeg, Manitoba, Canada 
Area:
Physiology Biology, Molecular Biology, Neuroscience Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Aldhshan MS, Mizuno TM. Environmental enrichment accentuates glucose-induced feeding suppression and glial cell line-derived neurotrophic factor gene expression in the hypothalamus of mice. Nutritional Neuroscience. 1-14. PMID 36634108 DOI: 10.1080/1028415X.2023.2165938  0.493
2022 Aldhshan MS, Jhanji G, Mizuno TM. Glucose and fructose directly stimulate brain-derived neurotrophic factor gene expression in microglia. Neuroreport. 33: 583-589. PMID 36049163 DOI: 10.1097/WNR.0000000000001820  0.418
2022 Aldhshan MS, Jhanji G, Poritsanos NJ, Mizuno TM. Glucose Stimulates Glial Cell Line-Derived Neurotrophic Factor Gene Expression in Microglia through a GLUT5-Independent Mechanism. International Journal of Molecular Sciences. 23. PMID 35806073 DOI: 10.3390/ijms23137073  0.745
2021 Mizuno TM, Lew PS, Jhanji G. Regulation of the Fructose Transporter Gene Expression by Glucose in Cultured Microglial Cells. International Journal of Molecular Sciences. 22. PMID 34884473 DOI: 10.3390/ijms222312668  0.455
2019 Mizuno T, Lew PS. SAT-183 Activating Transcription Factor 4 (ATF4) As A Possible Mediator Of Gluconeogenic And Lipogenic Actions Of Fat Mass And Obesity Associated (FTO) In Liver Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-183  0.386
2018 Mizuno TM. Fat Mass and Obesity Associated () Gene and Hepatic Glucose and Lipid Metabolism. Nutrients. 10. PMID 30388740 DOI: 10.3390/Nu10111600  0.579
2018 Bhavya S, Lew PS, Mizuno TM. Stimulation of white adipose tissue lipolysis by xenin, a neurotensin-related peptide. Biochemical and Biophysical Research Communications. PMID 29530527 DOI: 10.1016/J.Bbrc.2018.03.067  0.448
2017 Anderson JE, Zhu A, Mizuno TM. Nitric oxide treatment attenuates muscle atrophy during hind limb suspension in mice. Free Radical Biology & Medicine. 115: 458-470. PMID 29277394 DOI: 10.1016/J.Freeradbiomed.2017.12.021  0.351
2017 Bhavya S, Lew PS, Mizuno TM. Central action of xenin affects the expression of lipid metabolism-related genes and proteins in mouse white adipose tissue. Neuropeptides. PMID 28190525 DOI: 10.1016/J.Npep.2017.01.007  0.502
2016 Mizuno TM, Lew PS, Luo Y, Leckstrom A. Negative regulation of hepatic fat mass and obesity associated (Fto) gene expression by insulin. Life Sciences. PMID 27914922 DOI: 10.1016/J.Lfs.2016.11.027  0.558
2016 Kim ER, Lew PS, Spirkina A, Mizuno TM. Xenin-induced feeding suppression is not mediated through the activation of central extracellular signal-regulated kinase signaling in mice. Behavioural Brain Research. PMID 27316340 DOI: 10.1016/J.Bbr.2016.06.026  0.368
2015 Mizuno TM. β-Hydroxypyruvate: a new diabetogenic factor? Diabetes. 64: 1099-101. PMID 25805762 DOI: 10.2337/Db14-1830  0.475
2014 Kim ER, Xu Y, Mizuno TM. Impaired suppression of feeding by the gut hormone xenin in type I interleukin-1 receptor-deficient mice. Behavioural Brain Research. 261: 60-4. PMID 24333379 DOI: 10.1016/J.Bbr.2013.12.005  0.374
2013 Mizuno TM, Lew PS, Spirkina A, Xu Y. Mediation of glucose-induced anorexia by central nervous system interleukin 1 signaling. Behavioural Brain Research. 256: 512-9. PMID 24013028 DOI: 10.1016/J.Bbr.2013.08.050  0.435
2011 Poritsanos NJ, Lew PS, Fischer J, Mobbs CV, Nagy JI, Wong D, Rüther U, Mizuno TM. Impaired hypothalamic Fto expression in response to fasting and glucose in obese mice. Nutrition & Diabetes. 1: e19. PMID 23154321 DOI: 10.1038/Nutd.2011.15  0.766
2011 Leckstrom A, Lew PS, Poritsanos NJ, Mizuno TM. Central melanocortin receptor agonist reduces hepatic lipogenic gene expression in streptozotocin-induced diabetic mice. Life Sciences. 88: 664-9. PMID 21315740 DOI: 10.1016/J.Lfs.2011.01.026  0.758
2011 Leckstrom A, Lew PS, Poritsanos NJ, Mizuno TM. Treatment with a melanocortin agonist improves abnormal lipid metabolism in streptozotocin-induced diabetic mice. Neuropeptides. 45: 123-9. PMID 21216462 DOI: 10.1016/J.Npep.2010.12.005  0.742
2010 Poritsanos NJ, Lew PS, Mizuno TM. Relationship between blood glucose levels and hepatic Fto mRNA expression in mice. Biochemical and Biophysical Research Communications. 400: 713-7. PMID 20816934 DOI: 10.1016/J.Bbrc.2010.08.133  0.777
2010 Sangle GV, Zhao R, Mizuno TM, Shen GX. Involvement of RAGE, NADPH oxidase, and Ras/Raf-1 pathway in glycated LDL-induced expression of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells. Endocrinology. 151: 4455-66. PMID 20630999 DOI: 10.1210/En.2010-0323  0.366
2010 Kim ER, Mizuno TM. Xenin delays gastric emptying rate and activates the brainstem in mice. Neuroscience Letters. 481: 59-63. PMID 20599589 DOI: 10.1016/J.Neulet.2010.06.055  0.3
2010 Kim ER, Mizuno TM. Role of neurotensin receptor 1 in the regulation of food intake by neuromedins and neuromedin-related peptides. Neuroscience Letters. 468: 64-7. PMID 19857548 DOI: 10.1016/J.Neulet.2009.10.064  0.374
2009 Lew PS, Wong D, Yamaguchi T, Leckstrom A, Schwartz J, Dodd JG, Mizuno TM. Tail suspension increases energy expenditure independently of the melanocortin system in mice. Canadian Journal of Physiology and Pharmacology. 87: 839-49. PMID 20052010 DOI: 10.1139/Y09-074  0.37
2009 Poritsanos NJ, Mizuno TM, Lautatzis ME, Vrontakis M. Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. International Journal of Obesity (2005). 33: 1381-9. PMID 19773738 DOI: 10.1038/Ijo.2009.187  0.725
2009 Parkinson FE, Xiong W, Zamzow CR, Chestley T, Mizuno T, Duckworth ML. Transgenic expression of human equilibrative nucleoside transporter 1 in mouse neurons. Journal of Neurochemistry. 109: 562-72. PMID 19222701 DOI: 10.1111/J.1471-4159.2009.05991.X  0.429
2009 Leckstrom A, Kim ER, Wong D, Mizuno TM. Xenin, a gastrointestinal peptide, regulates feeding independent of the melanocortin signaling pathway. Diabetes. 58: 87-94. PMID 18984739 DOI: 10.14341/2071-8713-4884  0.317
2008 Poritsanos NJ, Wong D, Vrontakis ME, Mizuno TM. Regulation of hepatic PPARgamma2 and lipogenic gene expression by melanocortin. Biochemical and Biophysical Research Communications. 376: 384-8. PMID 18789887 DOI: 10.1016/J.Bbrc.2008.08.162  0.744
2008 Kim ER, Leckstrom A, Mizuno TM. Impaired anorectic effect of leptin in neurotensin receptor 1-deficient mice. Behavioural Brain Research. 194: 66-71. PMID 18639588 DOI: 10.1016/J.Bbr.2008.06.024  0.432
2008 Zhao R, Mizuno T, Lecksrom A, Moghadasain M, Shen GX. Involvement of heat shock factor-1(HSF1) in upregulation of plasminogen activator lnhihitor-1 in streptozotocin-induced diabetic, apolipoprotein E-knockout mice and fibroblasts from HSF1- knockout mice. Canadian Journal of Diabetes. 32: 309. DOI: 10.1016/S1499-2671(08)24045-1  0.359
2007 Yang XJ, Mastaitis J, Mizuno T, Mobbs CV. Glucokinase regulates reproductive function, glucocorticoid secretion, food intake, and hypothalamic gene expression. Endocrinology. 148: 1928-32. PMID 17218412 DOI: 10.1210/En.2006-1312  0.496
2005 Watson E, Hahm S, Mizuno TM, Windsor J, Montgomery C, Scherer PE, Mobbs CV, Salton SR. VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity. Endocrinology. 146: 5151-63. PMID 16141392 DOI: 10.1210/En.2005-0588  0.44
2005 Mobbs CV, Isoda F, Makimura H, Mastaitis J, Mizuno T, Shu IW, Yen K, Yang XJ. Impaired glucose signaling as a cause of obesity and the metabolic syndrome: the glucoadipostatic hypothesis. Physiology & Behavior. 85: 3-23. PMID 15924903 DOI: 10.1016/J.Physbeh.2005.04.005  0.435
2004 Mizuno TM, Funabashi T, Kleopoulos SP, Mobbs CV. Specific preservation of biosynthetic responses to insulin in adipose tissue may contribute to hyperleptinemia in insulin-resistant obese mice. The Journal of Nutrition. 134: 1045-50. PMID 15113943 DOI: 10.1093/Jn/134.5.1045  0.412
2003 Mizuno TM, Kelley KA, Pasinetti GM, Roberts JL, Mobbs CV. Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese mice. Diabetes. 52: 2675-83. PMID 14578285 DOI: 10.2337/Diabetes.52.11.2675  0.535
2003 Mizuno TM, Makimura H, Mobbs CV. The physiological function of the agouti-related peptide gene: the control of weight and metabolic rate. Annals of Medicine. 35: 425-33. PMID 14572167 DOI: 10.1080/07853890310012076  0.35
2003 Makimura H, Mizuno TM, Isoda F, Beasley J, Silverstein JH, Mobbs CV. Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression. Bmc Physiology. 3: 5. PMID 12848900 DOI: 10.1186/1472-6793-3-5  0.37
2003 Makimura H, Mizuno TM, Beasley J, Silverstein JH, Mobbs CV. Adrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesity. Bmc Physiology. 3: 4. PMID 12795810 DOI: 10.1186/1472-6793-3-4  0.368
2002 Makimura H, Mizuno TM, Mastaitis JW, Agami R, Mobbs CV. Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake. Bmc Neuroscience. 3: 18. PMID 12423556 DOI: 10.1186/1471-2202-3-18  0.352
2002 Makimura H, Mizuno TM, Bergen H, Mobbs CV. Adiponectin is stimulated by adrenalectomy in ob/ob mice and is highly correlated with resistin mRNA. American Journal of Physiology. Endocrinology and Metabolism. 283: E1266-71. PMID 12388167 DOI: 10.1152/Ajpendo.00227.2002  0.434
2002 Hahm S, Fekete C, Mizuno TM, Windsor J, Yan H, Boozer CN, Lee C, Elmquist JK, Lechan RM, Mobbs CV, Salton SR. VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6929-38. PMID 12177191 DOI: 10.1523/Jneurosci.22-16-06929.2002  0.408
2001 Makimura H, Mizuno TM, Yang XJ, Silverstein J, Beasley J, Mobbs CV. Cerulenin mimics effects of leptin on metabolic rate, food intake, and body weight independent of the melanocortin system, but unlike leptin, cerulenin fails to block neuroendocrine effects of fasting. Diabetes. 50: 733-9. PMID 11289036 DOI: 10.2337/Diabetes.50.4.733  0.456
2000 Makimura H, Mizuno TM, Roberts J, Silverstein J, Beasley J, Mobbs CV. Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice. Diabetes. 49: 1917-23. PMID 11078460 DOI: 10.2337/Diabetes.49.11.1917  0.435
1999 Mizuno TM, Makimura H, Silverstein J, Roberts JL, Lopingco T, Mobbs CV. Fasting Regulates Hypothalamic Neuropeptide Y, Agouti-Related Peptide, and Proopiomelanocortin in Diabetic Mice Independent of Changes in Leptin or Insulin1. Endocrinology. 140: 4551-4557. PMID 28200441 DOI: 10.1210/endo.140.10.6966  0.314
1999 Bergen HT, Mizuno T, Taylor J, Mobbs CV. Resistance to diet-induced obesity is associated with increased proopiomelanocortin mRNA and decreased neuropeptide Y mRNA in the hypothalamus. Brain Research. 851: 198-203. PMID 10642844 DOI: 10.1016/S0006-8993(99)02186-1  0.352
1999 Mizuno TM, Makimura H, Silverstein J, Roberts JL, Lopingco T, Mobbs CV. Fasting regulates hypothalamic neuropeptide Y, agouti-related peptide, and proopiomelanocortin in diabetic mice independent of changes in leptin or insulin. Endocrinology. 140: 4551-7. PMID 10499510 DOI: 10.1210/Endo.140.10.6966  0.461
1999 Hahm S, Mizuno TM, Wu TJ, Wisor JP, Priest CA, Kozak CA, Boozer CN, Peng B, McEvoy RC, Good P, Kelley KA, Takahashi JS, Pintar JE, Roberts JL, Mobbs CV, et al. Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance. Neuron. 23: 537-48. PMID 10433265 DOI: 10.1016/S0896-6273(00)80806-5  0.37
1999 Mizuno TM, Mobbs CV. Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting. Endocrinology. 140: 814-7. PMID 9927310 DOI: 10.1210/Endo.140.2.6491  0.331
1998 Bergen HT, Mizuno TM, Taylor J, Mobbs CV. Hyperphagia and weight gain after gold-thioglucose: relation to hypothalamic neuropeptide Y and proopiomelanocortin. Endocrinology. 139: 4483-8. PMID 9794456 DOI: 10.1210/Endo.139.11.6324  0.337
1998 Mizuno TM, Kleopoulos SP, Bergen HT, Roberts JL, Priest CA, Mobbs CV. Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin. Diabetes. 47: 294-7. PMID 9519731 DOI: 10.2337/Diab.47.2.294  0.324
1998 Mueller WM, Gregoire FM, Stanhope KL, Mobbs CV, Mizuno TM, Warden CH, Stern JS, Havel PJ. Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology. 139: 551-8. PMID 9449624 DOI: 10.1210/Endo.139.2.5716  0.391
1996 Mizuno T, Bergen H, Kleopoulos S, Bauman WA, Mobbs CV. Effects of nutritional status and aging on leptin gene expression in mice: importance of glucose. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 28: 679-84. PMID 9013741 DOI: 10.1055/s-2007-979877  0.387
1996 Mizuno TM, Bergen H, Funabashi T, Kleopoulos SP, Zhong YG, Bauman WA, Mobbs CV. Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity. Proceedings of the National Academy of Sciences of the United States of America. 93: 3434-8. PMID 8622953 DOI: 10.1073/Pnas.93.8.3434  0.473
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