Richard Bazinet - Publications

Affiliations: 
Nutritional Sciences University of Toronto, Toronto, ON, Canada 
Area:
Nutrition, Neuroscience Biology

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lin L, Metherel AH, Di Miceli M, Liu Z, Sahin C, Fioramonti X, Cummins CL, Layé S, Bazinet RP. Tetracosahexaenoylethanolamide, a novel n-acylethanolamide, is elevated in ischemia and increases neuronal output. Journal of Lipid Research. PMID 32826272 DOI: 10.1194/jlr.RA120001024  0.44
2019 Alashmali SM, Lin L, Trépanier MO, Cisbani G, Bazinet RP. The effects of n-6 polyunsaturated fatty acid deprivation on the inflammatory gene response to lipopolysaccharide in the mouse hippocampus. Journal of Neuroinflammation. 16: 237. PMID 31775778 DOI: 10.1186/s12974-019-1615-0  0.52
2019 Otoki Y, Metherel AH, Pedersen T, Yang J, Hammock BD, Bazinet RP, Newman JW, Taha AY. Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. Lipids. PMID 31691988 DOI: 10.1002/lipd.12197  0.44
2019 Santaren ID, Bazinet RP, Liu Z, Johnston LW, Sievenpiper JL, Giacca A, Retnakaran R, Harris SB, Zinman B, Hanley AJ. The Distribution of Fatty Acid Biomarkers of Dairy Intake across Serum Lipid Fractions: The Prospective Metabolism and Islet Cell Evaluation (PROMISE) Cohort. Lipids. PMID 31429083 DOI: 10.1002/lipd.12185  0.44
2019 Bazinet RP, Metherel AH, Chen CT, Raza Shaikh S, Nadjar A, Joffre C, Layé S. Brain eicosapentaenoic acid metabolism as a lead for novel therapeutics in major depression. Brain, Behavior, and Immunity. PMID 31278982 DOI: 10.1016/j.bbi.2019.07.001  0.44
2019 Pitino MA, Alashmali SM, Hopperton KE, Unger S, Pouliot Y, Doyen A, O'Connor DL, Bazinet RP. Oxylipin concentration, but not fatty acid composition, is altered in human donor milk pasteurized using both thermal and non-thermal techniques. The British Journal of Nutrition. 1-21. PMID 31006410 DOI: 10.1017/S0007114519000916  0.36
2019 Metherel AH, Irfan M, Chouinard-Watkins R, Trépanier MO, Stark KD, Bazinet RP. DHA Cycling Halves the DHA Supplementation Needed to Maintain Blood and Tissue Concentrations via Higher Synthesis from ALA in Long-Evans Rats. The Journal of Nutrition. PMID 30715388 DOI: 10.1093/jn/nxy282  0.52
2018 Taha AY, Trepanier MO, Coibanu FA, Saxena A, Jeffrey MA, Taha NMY, Burnham WM, Bazinet RP. Dietary Omega-3 Polyunsaturated Fatty Acid Deprivation Does Not Alter Seizure Thresholds but May Prevent the Anti-seizure Effects of Injected Docosahexaenoic Acid in Rats. Frontiers in Neurology. 9: 1188. PMID 30804888 DOI: 10.3389/fneur.2018.01188  0.44
2018 Hennebelle M, Metherel AH, Kitson AP, Otoki Y, Yang J, Lee KSS, Hammock BD, Bazinet RP, Taha AY. Brain oxylipin concentrations following hypercapnia / ischemia: effects of brain dissection and dissection time. Journal of Lipid Research. PMID 30463986 DOI: 10.1194/jlr.D084228  0.44
2018 Lin L, Metherel AH, Kitson AP, Alashmali SM, Hopperton KE, Trépanier MO, Jones PJ, Bazinet RP. Dietary fatty acids augment tissue levels of n-acylethanolamines in n-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) knockout mice. The Journal of Nutritional Biochemistry. 62: 134-142. PMID 30290332 DOI: 10.1016/j.jnutbio.2018.08.015  0.52
2018 Giuliano V, Scott Lacombe RJ, Hopperton KE, Bazinet RP. Applying stable carbon isotopic analysis at the natural abundance level to determine the origin of docosahexaenoic acid in the brain of the fat-1 mouse. Biochimica Et Biophysica Acta. PMID 30075211 DOI: 10.1016/j.bbalip.2018.07.014  0.36
2018 Lin YH, Hibbeln JR, Domenichiello AF, Ramsden CE, Salem NM, Chen CT, Jin H, Courville AB, Majchrzak-Hong SF, Rapoport SI, Bazinet RP, Miller BV. Quantitation of Human Whole-Body Synthesis-Secretion Rates of Docosahexaenoic Acid and Eicosapentaenoate Acid from Circulating Unesterified α-Linolenic Acid at Steady State. Lipids. PMID 30074625 DOI: 10.1002/lipd.12055  0.44
2018 Metherel AH, Lacombe RJS, Aristizabal Henao JJ, Morin-Rivron D, Kitson AP, Hopperton KE, Chalil D, Masoodi M, Stark KD, Bazinet RP. Two weeks of docosahexaenoic acid (DHA) supplementation increases synthesis-secretion kinetics of n-3 polyunsaturated fatty acids compared to 8 weeks of DHA supplementation. The Journal of Nutritional Biochemistry. 60: 24-34. PMID 30041049 DOI: 10.1016/j.jnutbio.2018.07.002  0.36
2018 Johnston LW, Liu Z, Retnakaran R, Zinman B, Giacca A, Harris SB, Bazinet RP, Hanley AJ. Clusters of fatty acids in the serum triacylglyceride fraction associate with the disorders of type 2 diabetes. Journal of Lipid Research. PMID 29986954 DOI: 10.1194/jlr.P084970  0.44
2018 Trépanier MO, Hopperton KE, Giuliano V, Masoodi M, Bazinet RP. Increased brain docosahexaenoic acid has no effect on the resolution of neuroinflammation following intracerebroventricular lipopolysaccharide injection. Neurochemistry International. PMID 29792954 DOI: 10.1016/j.neuint.2018.05.010  0.52
2018 Trépanier MO, Hildebrand KD, Nyamoya SD, Amor S, Bazinet RP, Kipp M. Phosphatidylcholine 36:1 concentration decreases along with demyelination in the cuprizone animal model and post-mortem of multiple sclerosis brain tissue. Journal of Neurochemistry. PMID 29574981 DOI: 10.1111/jnc.14335  0.52
2017 Johnston LW, Harris SB, Retnakaran R, Giacca A, Liu Z, Bazinet RP, Hanley AJ. Association of NEFA composition with insulin sensitivity and beta cell function in the Prospective Metabolism and Islet Cell Evaluation (PROMISE) cohort. Diabetologia. PMID 29275428 DOI: 10.1007/s00125-017-4534-6  0.44
2017 Hopperton KE, Mohammad D, Trépanier MO, Giuliano V, Bazinet RP. Markers of microglia in post-mortem brain samples from patients with Alzheimer's disease: a systematic review. Molecular Psychiatry. PMID 29230021 DOI: 10.1038/mp.2017.246  0.52
2017 Metherel AH, Lacombe RJS, Chouinard-Watkins RE, Hopperton KE, Bazinet RP. Complete assessment of whole-body n-3 and n-6 PUFA synthesis-secretion kinetics and DHA turnover in a rodent model. Journal of Lipid Research. PMID 29229739 DOI: 10.1194/jlr.M081380  0.36
2017 Metherel AH, Chouinard-Watkins R, Trépanier MO, Lacombe RJS, Bazinet RP. Retroconversion is a minor contributor to increases in eicosapentaenoic acid following docosahexaenoic acid feeding as determined by compound specific isotope analysis in rat liver. Nutrition & Metabolism. 14: 75. PMID 29209405 DOI: 10.1186/s12986-017-0230-2  0.52
2017 Hopperton KE, James NCE, Mohammad D, Irfan M, Bazinet RP. Dietary fish oil, and to a lesser extent the fat-1 transgene, increases astrocyte activation in response to intracerebroventricular amyloid-β 1-40 in mice. Nutritional Neuroscience. 1-7. PMID 29113539 DOI: 10.1080/1028415X.2017.1396068  0.36
2017 Hopperton KE, Trépanier MO, James NCE, Chouinard-Watkins R, Bazinet RP. Fish oil feeding attenuates neuroinflammatory gene expression without concomitant changes in brain eicosanoids and docosanoids in a mouse model of Alzheimer's disease. Brain, Behavior, and Immunity. PMID 29109025 DOI: 10.1016/j.bbi.2017.11.002  0.52
2017 Metherel AH, Kitson AP, Domenichiello AF, Lacombe RJS, Hopperton KE, Trépanier MO, Alashmali SM, Lin L, Bazinet RP. Docosahexaenoic acid (DHA) accretion in the placenta but not the fetus is matched by plasma unesterified DHA uptake rates in pregnant Long Evans rats. Placenta. 58: 90-97. PMID 28962703 DOI: 10.1016/j.placenta.2017.08.072  0.52
2017 Chouinard-Watkins R, Chen CT, Metherel AH, Lacombe RJS, Thies F, Masoodi M, Bazinet RP. Phospholipid class-specific brain enrichment in response to lysophosphatidylcholine docosahexaenoic acid infusion. Biochimica Et Biophysica Acta. 1862: 1092-1098. PMID 28760485 DOI: 10.1016/j.bbalip.2017.07.013  0.44
2017 Hennebelle M, Zhang Z, Metherel AH, Kitson AP, Otoki Y, Richardson CE, Yang J, Lee KSS, Hammock BD, Zhang L, Bazinet RP, Taha AY. Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. Scientific Reports. 7: 4342. PMID 28659576 DOI: 10.1038/s41598-017-02914-7  0.44
2017 Metherel AH, Kitson AP, Domenichiello AF, Lacombe RJS, Hopperton KE, Trépanier MO, Alashmali SM, Lin L, Bazinet RP. Maternal liver docosahexaenoic acid (DHA) stores are increased via higher serum unesterified DHA uptake in pregnant long Evans rats. The Journal of Nutritional Biochemistry. 46: 143-150. PMID 28628798 DOI: 10.1016/j.jnutbio.2017.05.011  0.52
2017 Islam R, Trépanier MO, Milenkovic M, Horsfall W, Salahpour A, Bazinet RP, Ramsey AJ. Vulnerability to omega-3 deprivation in a mouse model of NMDA receptor hypofunction. Npj Schizophrenia. 3: 12. PMID 28560258 DOI: 10.1038/s41537-017-0014-8  0.52
2016 Trépanier MO, Eiden M, Morin-Rivron D, Bazinet RP, Masoodi M. High-resolution lipidomics coupled with rapid fixation reveals novel ischemia-induced signaling in the rat neurolipidome. Journal of Neurochemistry. PMID 28002627 DOI: 10.1111/jnc.13934  0.52
2016 Domenichiello AF, Kitson AP, Metherel AH, Chen CT, Hopperton KE, Stavro PM, Bazinet RP. Whole-Body Docosahexaenoic Acid Synthesis-Secretion Rates in Rats Are Constant across a Large Range of Dietary α-Linolenic Acid Intakes. The Journal of Nutrition. PMID 27852871 DOI: 10.3945/jn.116.232074  0.44
2016 Hopperton KE, Trépanier MO, Giuliano V, Bazinet RP. Brain omega-3 polyunsaturated fatty acids modulate microglia cell number and morphology in response to intracerebroventricular amyloid-β 1-40 in mice. Journal of Neuroinflammation. 13: 257. PMID 27688126 DOI: 10.1186/s12974-016-0721-5  0.52
2016 Metherel AH, Domenichiello AF, Kitson AP, Hopperton KE, Bazinet RP. Whole-body DHA synthesis-secretion kinetics from plasma eicosapentaenoic acid and alpha-linolenic acid in the free-living rat. Biochimica Et Biophysica Acta. PMID 27263420 DOI: 10.1016/j.bbalip.2016.05.014  0.36
2016 Johnston LW, Harris SB, Retnakaran R, Zinman B, Giacca A, Liu Z, Bazinet RP, Hanley AJ. Longitudinal associations of phospholipid and cholesteryl ester fatty acids with disorders underlying diabetes. The Journal of Clinical Endocrinology and Metabolism. jc20154267. PMID 27144932 DOI: 10.1210/jc.2015-4267  1
2016 Kitson AP, Metherel AH, Chen CT, Domenichiello AF, Trépanier MO, Berger A, Bazinet RP. Effect of dietary docosahexaenoic acid (DHA) in phospholipids or triglycerides on brain DHA uptake and accretion. The Journal of Nutritional Biochemistry. 33: 91-102. PMID 27135386 DOI: 10.1016/j.jnutbio.2016.02.009  1
2016 Domenichiello AF, Kitson AP, Chen CT, Trépanier MO, Stavro PM, Bazinet RP. The effect of linoleic acid on the whole body synthesis rates of polyunsaturated fatty acids from α-linolenic acid and linoleic acid in free-living rats. The Journal of Nutritional Biochemistry. 30: 167-76. PMID 27012633 DOI: 10.1016/j.jnutbio.2015.11.016  0.52
2016 Alashmali SM, Hopperton KE, Bazinet RP. Lowering dietary n-6 polyunsaturated fatty acids: interaction with brain arachidonic and docosahexaenoic acids. Current Opinion in Lipidology. 27: 54-66. PMID 26709472 DOI: 10.1097/MOL.0000000000000255  0.36
2015 Chen CT, Kitson AP, Hopperton KE, Domenichiello AF, Trépanier MO, Lin LE, Ermini L, Post M, Thies F, Bazinet RP. Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain. Scientific Reports. 5: 15791. PMID 26511533 DOI: 10.1038/srep15791  1
2015 Sánchez-Hernández D, Poon AN, Kubant R, Kim H, Huot PS, Cho CE, Pannia E, Reza-López SA, Pausova Z, Bazinet RP, Anderson GH. High vitamin A intake during pregnancy modifies dopaminergic reward system and decreases preference for sucrose in Wistar rat offspring. The Journal of Nutritional Biochemistry. PMID 26456562 DOI: 10.1016/j.jnutbio.2015.08.020  1
2015 Trépanier MO, Kwong KM, Domenichiello AF, Chen CT, Bazinet RP, Burnham WM. Intravenous infusion of docosahexaenoic acid increases serum concentrations in a dose-dependent manner and increases seizure latency in the maximal PTZ model. Epilepsy & Behavior : E&B. 50: 71-76. PMID 26141815 DOI: 10.1016/j.yebeh.2015.05.034  1
2015 Trépanier MO, Hopperton KE, Orr SK, Bazinet RP. N-3 polyunsaturated fatty acids in animal models with neuroinflammation: An update. European Journal of Pharmacology. PMID 26036964 DOI: 10.1016/j.ejphar.2015.05.045  1
2015 Pillon NJ, Azizi PM, Li YE, Liu J, Wang C, Chan KL, Hopperton KE, Bazinet RP, Heit B, Bilan PJ, Lee WL, Klip A. Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promotes monocyte adhesion and impairs insulin transcytosis. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00611.2014. PMID 25944880 DOI: 10.1152/ajpendo.00611.2014  0.36
2015 Cho CE, Pannia E, Huot PS, Sánchez-Hernández D, Kubant R, Dodington DW, Ward WE, Bazinet RP, Anderson GH. Methyl vitamins contribute to obesogenic effects of a high multivitamin gestational diet and epigenetic alterations in hypothalamic feeding pathways in Wistar rat offspring. Molecular Nutrition & Food Research. 59: 476-89. PMID 25488374 DOI: 10.1002/mnfr.201400663  1
2015 Lin LE, Chen CT, Hildebrand KD, Liu Z, Hopperton KE, Bazinet RP. Chronic dietary n-6 PUFA deprivation leads to conservation of arachidonic acid and more rapid loss of DHA in rat brain phospholipids. Journal of Lipid Research. 56: 390-402. PMID 25477531 DOI: 10.1194/jlr.M055590  0.44
2015 Parrott MD, Winocur G, Bazinet RP, Ma DW, Greenwood CE. Whole-food diet worsened cognitive dysfunction in an Alzheimer's disease mouse model. Neurobiology of Aging. 36: 90-9. PMID 25212462 DOI: 10.1016/j.neurobiolaging.2014.08.013  1
2015 Chen CT, Bazinet RP. β-oxidation and rapid metabolism, but not uptake regulate brain eicosapentaenoic acid levels. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 92: 33-40. PMID 24986271 DOI: 10.1016/j.plefa.2014.05.007  0.44
2014 Nishi S, Kendall CW, Gascoyne AM, Bazinet RP, Bashyam B, Lapsley KG, Augustin LS, Sievenpiper JL, Jenkins DJ. Effect of almond consumption on the serum fatty acid profile: a dose-response study. The British Journal of Nutrition. 112: 1137-46. PMID 25138064 DOI: 10.1017/S0007114514001640  1
2014 Ha V, Sievenpiper JL, de Souza RJ, Jayalath VH, Mirrahimi A, Agarwal A, Chiavaroli L, Mejia SB, Sacks FM, Di Buono M, Bernstein AM, Leiter LA, Kris-Etherton PM, Vuksan V, Bazinet RP, et al. Effect of dietary pulse intake on established therapeutic lipid targets for cardiovascular risk reduction: a systematic review and meta-analysis of randomized controlled trials. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 186: E252-62. PMID 24710915 DOI: 10.1503/cmaj.131727  1
2014 Trépanier MO, Lim J, Lai TK, Cho HJ, Domenichiello AF, Chen CT, Taha AY, Bazinet RP, Burnham WM. Intraperitoneal administration of docosahexaenoic acid for 14days increases serum unesterified DHA and seizure latency in the maximal pentylenetetrazol model. Epilepsy & Behavior : E&B. 33: 138-43. PMID 24662925 DOI: 10.1016/j.yebeh.2014.02.020  1
2014 Chen CT, Trépanier MO, Hopperton KE, Domenichiello AF, Masoodi M, Bazinet RP. Inhibiting mitochondrial β-oxidation selectively reduces levels of nonenzymatic oxidative polyunsaturated fatty acid metabolites in the brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 376-9. PMID 24326387 DOI: 10.1038/jcbfm.2013.221  0.52
2014 Francis BM, Yang J, Song BJ, Gupta S, Maj M, Bazinet RP, Robinson B, Mount HT. Reduced levels of mitochondrial complex I subunit NDUFB8 and linked complex I + III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 39: 347-55. PMID 24217272 DOI: 10.3233/JAD-131499  1
2014 Domenichiello AF, Chen CT, Trepanier MO, Stavro PM, Bazinet RP. Whole body synthesis rates of DHA from α-linolenic acid are greater than brain DHA accretion and uptake rates in adult rats. Journal of Lipid Research. 55: 62-74. PMID 24212299 DOI: 10.1194/jlr.M042275  1
2014 Hopperton KE, Duncan RE, Bazinet RP, Archer MC. Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity. Experimental Cell Research. 320: 302-10. PMID 24200503 DOI: 10.1016/j.yexcr.2013.10.016  1
2013 Taha AY, Zahid T, Epps T, Trepanier MO, Burnham WM, Bazinet RP, Zhang L. Selective reduction of excitatory hippocampal sharp waves by docosahexaenoic acid and its methyl ester analog ex-vivo. Brain Research. 1537: 9-17. PMID 24036166 DOI: 10.1016/j.brainres.2013.09.004  1
2013 Orr SK, Palumbo S, Bosetti F, Mount HT, Kang JX, Greenwood CE, Ma DW, Serhan CN, Bazinet RP. Unesterified docosahexaenoic acid is protective in neuroinflammation. Journal of Neurochemistry. 127: 378-93. PMID 23919613 DOI: 10.1111/jnc.12392  1
2013 Chen CT, Domenichiello AF, Trépanier MO, Liu Z, Masoodi M, Bazinet RP. The low levels of eicosapentaenoic acid in rat brain phospholipids are maintained via multiple redundant mechanisms. Journal of Lipid Research. 54: 2410-22. PMID 23836105 DOI: 10.1194/jlr.M038505  0.52
2013 Taha AY, Trepanier MO, Ciobanu FA, Taha NM, Ahmed M, Zeng Q, Cheuk WI, Ip B, Filo E, Scott BW, Burnham WM, Bazinet RP. A minimum of 3 months of dietary fish oil supplementation is required to raise amygdaloid afterdischarge seizure thresholds in rats--implications for treating complex partial seizures. Epilepsy & Behavior : E&B. 27: 49-58. PMID 23376336 DOI: 10.1016/j.yebeh.2012.12.004  1
2013 Orr SK, Trépanier MO, Bazinet RP. n-3 Polyunsaturated fatty acids in animal models with neuroinflammation. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 88: 97-103. PMID 22770766 DOI: 10.1016/j.plefa.2012.05.008  1
2012 Ramadeen A, Connelly KA, Leong-Poi H, Hu X, Fujii H, Laurent G, Domenichiello AF, Bazinet RP, Dorian P. Docosahexaenoic acid, but not eicosapentaenoic acid, supplementation reduces vulnerability to atrial fibrillation. Circulation. Arrhythmia and Electrophysiology. 5: 978-83. PMID 22923273 DOI: 10.1161/CIRCEP.112.971515  1
2012 Arsenault D, Julien C, Chen CT, Bazinet RP, Calon F. Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in mice. Journal of Neurochemistry. 122: 427-43. PMID 22551210 DOI: 10.1111/j.1471-4159.2012.07772.x  1
2012 Ramadeen A, Connelly KA, Leong-Poi H, Hu X, Fujii H, Van Krieken R, Laurent G, Holub BJ, Bazinet RP, Dorian P. N-3 polyunsaturated fatty acid supplementation does not reduce vulnerability to atrial fibrillation in remodeling atria. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 1115-1122.e4. PMID 22342864 DOI: 10.1016/j.hrthm.2012.02.013  1
2012 Trépanier MO, Taha AY, Mantha RL, Ciobanu FA, Zeng QH, Tchkhartichvili GM, Domenichiello AF, Bazinet RP, Burnham WM. Increases in seizure latencies induced by subcutaneous docosahexaenoic acid are lost at higher doses. Epilepsy Research. 99: 225-32. PMID 22285511 DOI: 10.1016/j.eplepsyres.2011.12.001  1
2012 Shi SY, Martin RG, Duncan RE, Choi D, Lu SY, Schroer SA, Cai EP, Luk CT, Hopperton KE, Domenichiello AF, Tang C, Naples M, Dekker MJ, Giacca A, Adeli K, ... ... Bazinet RP, et al. Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. The Journal of Biological Chemistry. 287: 10277-88. PMID 22275361 DOI: 10.1074/jbc.M111.317453  1
2011 Chen CT, Liu Z, Bazinet RP. Rapid de-esterification and loss of eicosapentaenoic acid from rat brain phospholipids: an intracerebroventricular study. Journal of Neurochemistry. 116: 363-73. PMID 21091476 DOI: 10.1111/j.1471-4159.2010.07116.x  0.44
2010 Song BJ, Elbert A, Rahman T, Orr SK, Chen CT, Febbraio M, Bazinet RP. Genetic ablation of CD36 does not alter mouse brain polyunsaturated fatty acid concentrations. Lipids. 45: 291-9. PMID 20306148 DOI: 10.1007/s11745-010-3398-z  1
2010 Orr SK, Tong JY, Kang JX, Ma DW, Bazinet RP. The fat-1 mouse has brain docosahexaenoic acid levels achievable through fish oil feeding. Neurochemical Research. 35: 811-9. PMID 20177777 DOI: 10.1007/s11064-010-0139-x  1
2010 Rahman T, Taha AY, Song BJ, Orr SK, Liu Z, Chen CT, Bazinet RP. The very low density lipoprotein receptor is not necessary for maintaining brain polyunsaturated fatty acid concentrations. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 82: 141-5. PMID 20106645 DOI: 10.1016/j.plefa.2009.11.003  1
2010 Lee HJ, Bazinet RP, Rapoport SI, Bhattacharjee AK. Brain arachidonic acid cascade enzymes are upregulated in a rat model of unilateral Parkinson disease. Neurochemical Research. 35: 613-9. PMID 19997776 DOI: 10.1007/s11064-009-0106-6  1
2010 Green JT, Liu Z, Bazinet RP. Brain phospholipid arachidonic acid half-lives are not altered following 15 weeks of N-3 polyunsaturated fatty acid adequate or deprived diet. Journal of Lipid Research. 51: 535-43. PMID 19661256 DOI: 10.1194/jlr.M000786  0.64
2009 Crawford MA, Bazinet RP, Sinclair AJ. Fat intake and CNS functioning: ageing and disease. Annals of Nutrition & Metabolism. 55: 202-28. PMID 19752543 DOI: 10.1159/000229003  1
2009 Sievenpiper JL, Kendall CW, Esfahani A, Wong JM, Carleton AJ, Jiang HY, Bazinet RP, Vidgen E, Jenkins DJ. Effect of non-oil-seed pulses on glycaemic control: a systematic review and meta-analysis of randomised controlled experimental trials in people with and without diabetes. Diabetologia. 52: 1479-95. PMID 19526214 DOI: 10.1007/s00125-009-1395-7  1
2009 Ouellet M, Emond V, Chen CT, Julien C, Bourasset F, Oddo S, LaFerla F, Bazinet RP, Calon F. Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood-brain barrier: An in situ cerebral perfusion study. Neurochemistry International. 55: 476-82. PMID 19442696 DOI: 10.1016/j.neuint.2009.04.018  1
2009 Chen CT, Liu Z, Ouellet M, Calon F, Bazinet RP. Rapid beta-oxidation of eicosapentaenoic acid in mouse brain: an in situ study. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 80: 157-63. PMID 19237271 DOI: 10.1016/j.plefa.2009.01.005  1
2009 Taha AY, Chen CT, Liu Z, Kim JH, Mount HT, Bazinet RP. Brainstem concentrations of cholesterol are not influenced by genetic ablation of the low-density lipoprotein receptor. Neurochemical Research. 34: 311-5. PMID 18607722 DOI: 10.1007/s11064-008-9777-7  1
2008 Chen CT, Green JT, Orr SK, Bazinet RP. Regulation of brain polyunsaturated fatty acid uptake and turnover. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 79: 85-91. PMID 18938067 DOI: 10.1016/j.plefa.2008.09.003  1
2008 Milligan LA, Bazinet RP. Evolutionary modifications of human milk composition: evidence from long-chain polyunsaturated fatty acid composition of anthropoid milks. Journal of Human Evolution. 55: 1086-95. PMID 18809203 DOI: 10.1016/j.jhevol.2008.07.010  1
2008 Orr SK, Bazinet RP. The emerging role of docosahexaenoic acid in neuroinflammation. Current Opinion in Investigational Drugs (London, England : 2000). 9: 735-43. PMID 18600579  1
2008 Bhattacharjee AK, Chang L, Chen M, White L, Bell JM, Bazinet RP, Rapoport SI. Chronic d-amphetamine depresses an imaging marker of arachidonic acid metabolism in rat brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 957-69. PMID 18570702 DOI: 10.1017/S1461145708008833  1
2008 Rao JS, Lee HJ, Rapoport SI, Bazinet RP. Mode of action of mood stabilizers: is the arachidonic acid cascade a common target? Molecular Psychiatry. 13: 585-96. PMID 18347600 DOI: 10.1038/mp.2008.31  1
2008 Bhattacharjee AK, Chang L, White L, Bazinet RP, Rapoport SI. Imaging apomorphine stimulation of brain arachidonic acid signaling via D2-like receptors in unanesthetized rats. Psychopharmacology. 197: 557-66. PMID 18274730 DOI: 10.1007/s00213-008-1073-3  1
2008 Green JT, Orr SK, Bazinet RP. The emerging role of group VI calcium-independent phospholipase A2 in releasing docosahexaenoic acid from brain phospholipids. Journal of Lipid Research. 49: 939-44. PMID 18252846 DOI: 10.1194/jlr.R700017-JLR200  1
2008 Lee HJ, Ertley RN, Rapoport SI, Bazinet RP, Rao JS. Chronic administration of lamotrigine downregulates COX-2 mRNA and protein in rat frontal cortex. Neurochemical Research. 33: 861-6. PMID 18080190 DOI: 10.1007/s11064-007-9526-3  1
2008 Lee HJ, Rao JS, Chang L, Rapoport SI, Bazinet RP. Chronic N-methyl-D-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat. Journal of Lipid Research. 49: 162-8. PMID 17957090 DOI: 10.1194/jlr.M700406-JLR200  1
2008 Chen CT, Ma DW, Kim JH, Mount HT, Bazinet RP. The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations. Journal of Lipid Research. 49: 147-52. PMID 17932396 DOI: 10.1194/jlr.M700386-JLR200  0.44
2008 Milligan LA, Rapoport SI, Cranfield MR, Dittus W, Glander KE, Oftedal OT, Power ML, Whittier CA, Bazinet RP. Fatty acid composition of wild anthropoid primate milks. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 149: 74-82. PMID 17916436 DOI: 10.1016/j.cbpb.2007.08.006  1
2007 Lee HJ, Rao JS, Rapoport SI, Bazinet RP. Antimanic therapies target brain arachidonic acid signaling: lessons learned about the regulation of brain fatty acid metabolism. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 77: 239-46. PMID 18042366 DOI: 10.1016/j.plefa.2007.10.018  1
2007 Vuksan V, Whitham D, Sievenpiper JL, Jenkins AL, Rogovik AL, Bazinet RP, Vidgen E, Hanna A. Supplementation of conventional therapy with the novel grain Salba (Salvia hispanica L.) improves major and emerging cardiovascular risk factors in type 2 diabetes: results of a randomized controlled trial. Diabetes Care. 30: 2804-10. PMID 17686832 DOI: 10.2337/dc07-1144  1
2007 Bhattacharjee AK, Meister LM, Chang L, Bazinet RP, White L, Rapoport SI. In vivo imaging of disturbed pre- and post-synaptic dopaminergic signaling via arachidonic acid in a rat model of Parkinson's disease. Neuroimage. 37: 1112-21. PMID 17681816 DOI: 10.1016/j.neuroimage.2007.06.012  1
2007 Rao JS, Bazinet RP, Rapoport SI, Lee HJ. Chronic treatment of rats with sodium valproate downregulates frontal cortex NF-kappaB DNA binding activity and COX-2 mRNA. Bipolar Disorders. 9: 513-20. PMID 17680922 DOI: 10.1111/j.1399-5618.2007.00361.x  1
2007 Rao JS, Ertley RN, Rapoport SI, Bazinet RP, Lee HJ. Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A2 and its transcription factor, activator protein-2. Journal of Neurochemistry. 102: 1918-27. PMID 17550430 DOI: 10.1111/j.1471-4159.2007.04648.x  1
2007 Lee HJ, Rao JS, Chang L, Rapoport SI, Bazinet RP. Chronic lamotrigine does not alter the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat: implications for the treatment of bipolar disorder. Psychopharmacology. 193: 467-74. PMID 17487474 DOI: 10.1007/s00213-007-0803-2  1
2007 Lee HJ, Rao JS, Ertley RN, Chang L, Rapoport SI, Bazinet RP. Chronic fluoxetine increases cytosolic phospholipase A(2) activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat. Psychopharmacology. 190: 103-15. PMID 17093977 DOI: 10.1007/s00213-006-0582-1  1
2007 Rao JS, Ertley RN, DeMar JC, Rapoport SI, Bazinet RP, Lee HJ. Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex. Molecular Psychiatry. 12: 151-7. PMID 16983392 DOI: 10.1038/sj.mp.4001887  1
2007 Rao JS, Ertley RN, Lee HJ, DeMar JC, Arnold JT, Rapoport SI, Bazinet RP. n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. Molecular Psychiatry. 12: 36-46. PMID 16983391 DOI: 10.1038/sj.mp.4001888  1
2007 Rao JS, Bazinet RP, Rapoport SI, Lee HJ. Chronic administration of carbamazepine down-regulates AP-2 DNA-binding activity and AP-2alpha protein expression in rat frontal cortex. Biological Psychiatry. 61: 154-61. PMID 16806101 DOI: 10.1016/j.biopsych.2006.03.029  1
2007 Ertley RN, Bazinet RP, Lee HJ, Rapoport SI, Rao JS. Chronic treatment with mood stabilizers increases membrane GRK3 in rat frontal cortex. Biological Psychiatry. 61: 246-9. PMID 16697355 DOI: 10.1016/j.biopsych.2006.03.022  1
2006 DeMar JC, Lee HJ, Ma K, Chang L, Bell JM, Rapoport SI, Bazinet RP. Brain elongation of linoleic acid is a negligible source of the arachidonate in brain phospholipids of adult rats. Biochimica Et Biophysica Acta. 1761: 1050-9. PMID 16920015 DOI: 10.1016/j.bbalip.2006.06.006  1
2006 Rao JS, Ertley RN, Lee HJ, Rapoport SI, Bazinet RP. Chronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortex. The Pharmacogenomics Journal. 6: 413-20. PMID 16636684 DOI: 10.1038/sj.tpj.6500391  1
2006 Bhattacharjee AK, Chang L, White L, Bazinet RP, Rapoport SI. D-Amphetamine stimulates D2 dopamine receptor-mediated brain signaling involving arachidonic acid in unanesthetized rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 1378-88. PMID 16511499 DOI: 10.1038/sj.jcbfm.9600290  1
2005 Bazinet RP, Lee HJ, Felder CC, Porter AC, Rapoport SI, Rosenberger TA. Rapid high-energy microwave fixation is required to determine the anandamide (N-arachidonoylethanolamine) concentration of rat brain. Neurochemical Research. 30: 597-601. PMID 16176062 DOI: 10.1007/s11064-005-2746-5  1
2004 Bazinet RP, Douglas H, McMillan EG, Wilkie BN, Cunnane SC. Dietary 18:3omega3 influences immune function and the tissue fatty acid response to antigens and adjuvant. Immunology Letters. 95: 85-90. PMID 15325802 DOI: 10.1016/j.imlet.2004.06.007  1
2003 Bazinet RP, Douglas H, McMillan EG, Wilkie BN, Cunnane SC. Intramuscular injection of antigens and adjuvant preferentially decreases 18:2n-6 and 18:3n-3 in pig neck muscle. Lipids. 38: 1221-6. PMID 14870924 DOI: 10.1007/s11745-003-1182-x  1
2003 Cunnane SC, Ryan MA, Nadeau CR, Bazinet RP, Musa-Veloso K, McCloy U. Why is carbon from some polyunsaturates extensively recycled into lipid synthesis? Lipids. 38: 477-84. PMID 12848297 DOI: 10.1007/s11745-003-1087-8  1
2003 Bazinet RP, McMillan EG, Seebaransingh R, Hayes AM, Cunnane SC. Whole-body beta-oxidation of 18:2omega6 and 18:3omega3 in the pig varies markedly with weaning strategy and dietary 18:3omega3. Journal of Lipid Research. 44: 314-9. PMID 12576513 DOI: 10.1194/jlr.M200153-JLR200  1
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