Richard Bazinet - Publications

Affiliations: 
Nutritional Sciences University of Toronto, Toronto, ON, Canada 
Area:
Nutrition, Neuroscience Biology

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Year Citation  Score
2023 Metherel AH, Klievik BJ, Cisbani G, Smith ME, Cumberford G, Bazinet RP. Blood and tissue docosahexaenoic acid (DHA, 22:6n-3) turnover rates from Ahiflower® oil are not different than from DHA ethyl ester oil in a diet switch mouse model. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1869: 159422. PMID 37977491 DOI: 10.1016/j.bbalip.2023.159422  0.334
2023 Chen DK, Metherel AH, Rezaei K, Parzanini C, Chen CT, Ramsden CE, Horowitz M, Faurot KR, MacIntosh B, Zamora D, Bazinet RP. Analysis of omega-3 and omega-6 polyunsaturated fatty acid metabolism by compound-specific isotope analysis in humans. Journal of Lipid Research. 100424. PMID 37572791 DOI: 10.1016/j.jlr.2023.100424  0.388
2023 Valenzuela R, Metherel AH, Cisbani G, Smith ME, Chouinard-Watkins R, Klievik BJ, Videla LA, Bazinet RP. Protein concentrations and activities of fatty acid desaturase and elongase enzymes in liver, brain, testicle, and kidney from mice: Substrate dependency. Biofactors (Oxford, England). PMID 37470206 DOI: 10.1002/biof.1992  0.412
2023 Martinsen A, Saleh RNM, Chouinard-Watkins R, Bazinet R, Harden G, Dick J, Tejera N, Pontifex MG, Vauzour D, Minihane AM. The Influence of Genotype, DHA, and Flavanol Intervention on Brain DHA and Lipidomics Profile in Aged Transgenic Mice. Nutrients. 15. PMID 37432149 DOI: 10.3390/nu15092032  0.508
2023 Klievik BJ, Tyrrell AD, Chen CT, Bazinet RP. Measuring brain docosahexaenoic acid turnover as a marker of metabolic consumption. Pharmacology & Therapeutics. 248: 108437. PMID 37201738 DOI: 10.1016/j.pharmthera.2023.108437  0.505
2023 Shaikh SR, Bazinet RP. Heterogeneity in the response to n-3 polyunsaturated fatty acids. Current Opinion in Clinical Nutrition and Metabolic Care. 26: 284-287. PMID 36943155 DOI: 10.1097/MCO.0000000000000930  0.379
2022 Lacombe RJS, Smith ME, Perlman K, Turecki G, Mechawar N, Bazinet RP. Quantitative and Carbon Isotope Ratio Analysis of Fatty Acids Isolated from Human Brain Hemispheres. Journal of Neurochemistry. PMID 36196762 DOI: 10.1111/jnc.15702  0.562
2022 Liu J, Sahin C, Ahmad S, Magomedova L, Zhang M, Jia Z, Metherel AH, Orellana A, Poda G, Bazinet RP, Attisano L, Cummins CL, Peng H, Krause HM. The omega-3 hydroxy fatty acid 7()-HDHA is a high-affinity PPARα ligand that regulates brain neuronal morphology. Science Signaling. 15: eabo1857. PMID 35857636 DOI: 10.1126/scisignal.abo1857  0.339
2022 Di Miceli M, Martinat M, Rossitto M, Aubert A, Alashmali S, Bosch-Bouju C, Fioramonti X, Joffre C, Bazinet RP, Layé S. Dietary Long-Chain n-3 Polyunsaturated Fatty Acid Supplementation Alters Electrophysiological Properties in the Nucleus Accumbens and Emotional Behavior in Naïve and Chronically Stressed Mice. International Journal of Molecular Sciences. 23. PMID 35743093 DOI: 10.3390/ijms23126650  0.397
2022 Hopperton KE, Pitino MA, Walton K, Kiss A, Unger SL, O'Connor DL, Bazinet RP. Docosahexaenoic acid and arachidonic acid levels are correlated in human milk: Implications for new European infant formula regulations. Lipids. PMID 35170053 DOI: 10.1002/lipd.12338  0.339
2022 Sylvestre DA, Otoki Y, Metherel AH, Bazinet RP, Slupsky CM, Taha AY. Effects of hypercapnia / ischemia and dissection on the rat brain metabolome. Neurochemistry International. 105294. PMID 35104537 DOI: 10.1016/j.neuint.2022.105294  0.363
2022 Cisbani G, Koppel A, Metherel AH, Smith ME, Aji KN, Andreazza AC, Mizrahi R, Bazinet RP. Serum lipid analysis and isotopic enrichment is suggestive of greater lipogenesis in young long-term cannabis users: A secondary analysis of a case-control study. Lipids. PMID 35075659 DOI: 10.1002/lipd.12336  0.353
2021 Furber KL, Lacombe RJS, Caine S, Thangaraj MP, Read S, Rosendahl SM, Bazinet RP, Popescu BF, Nazarali AJ. Biochemical Alterations in White Matter Tracts of the Aging Mouse Brain Revealed by FTIR Spectroscopy Imaging. Neurochemical Research. PMID 34820737 DOI: 10.1007/s11064-021-03491-y  0.313
2021 Smith ME, Cisbani G, Metherel AH, Bazinet RP. The Majority of Brain Palmitic Acid is Maintained by Lipogenesis from Dietary Sugars and is Augmented in Mice fed Low Palmitic Acid Levels from Birth. Journal of Neurochemistry. PMID 34780089 DOI: 10.1111/jnc.15539  0.442
2021 Cisbani G, Metherel AH, Smith ME, Bazinet RP. Murine and human microglial cells are relatively enriched with eicosapentaenoic acid compared to the whole brain. Neurochemistry International. 150: 105154. PMID 34384851 DOI: 10.1016/j.neuint.2021.105154  0.539
2021 Chouinard-Watkins R, Calleja M, Bazinet RP, Josse AR. Dairy product consumption is associated with a lowering of linoleic acid within serum triglycerides in adolescent females with overweight or obesity: a secondary analysis. The British Journal of Nutrition. 1-30. PMID 34027846 DOI: 10.1017/S0007114521001677  0.383
2021 Metherel AH, Rezaei K, Lacombe RJS, Bazinet RP. Plasma unesterified eicosapentaenoic acid is converted to docosahexaenoic acid (DHA) in the liver and supplies the brain with DHA in the presence or absence of dietary DHA. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1866: 158942. PMID 33845223 DOI: 10.1016/j.bbalip.2021.158942  0.5
2021 Simopoulos AP, Serhan CN, Bazinet RP. The need for precision nutrition, genetic variation and resolution in Covid-19 patients. Molecular Aspects of Medicine. 77: 100943. PMID 33551236 DOI: 10.1016/j.mam.2021.100943  0.427
2020 McCusker MR, Bazinet RP, Metherel AH, Klein RY, Kundra A, Haibe-Kains B, Li M. Nonesterified Fatty Acids and Depression in Cancer Patients and Caregivers. Current Developments in Nutrition. 4: nzaa156. PMID 33447694 DOI: 10.1093/cdn/nzaa156  0.33
2020 Pal A, Metherel AH, Fiabane L, Buddenbaum N, Bazinet RP, Shaikh SR. Do Eicosapentaenoic Acid and Docosahexaenoic Acid Have the Potential to Compete against Each Other? Nutrients. 12. PMID 33276463 DOI: 10.3390/nu12123718  0.474
2020 Cisbani G, Bazinet RP. The role of peripheral fatty acids as biomarkers for Alzheimer's disease and brain inflammation. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 164: 102205. PMID 33271431 DOI: 10.1016/j.plefa.2020.102205  0.401
2020 Lin L, Metherel AH, Di Miceli M, Liu Z, Sahin C, Fioramonti X, Cummins CL, Layé S, Bazinet RP. Tetracosahexaenoylethanolamide, a novel n-acylethanolamide, is elevated in ischemia and increases neuronal output. Journal of Lipid Research. PMID 32826272 DOI: 10.1194/Jlr.Ra120001024  0.531
2020 Chamorro R, Gonzalez MF, Aliaga R, Gengler V, Balladares C, Barrera C, Bascuñan KA, Bazinet RP, Valenzuela R. Diet, Plasma, Erythrocytes, and Spermatozoa Fatty Acid Composition Changes in Young Vegan Men. Lipids. PMID 32757304 DOI: 10.1002/lipd.12265  0.356
2020 Gabrielson DK, Brezden-Masley C, Keith M, Bazinet RP, Sykes J, Darling PB. Evaluation of Nutritional, Inflammatory, and Fatty Acid Status in Patients with Gastric and Colorectal Cancer Receiving Chemotherapy. Nutrition and Cancer. 1-13. PMID 32340493 DOI: 10.1080/01635581.2020.1756351  0.346
2020 Ho M, Anderson GH, Lin L, Bazinet RP, Kubant R. Ethanolamides of essential α-linolenic and linoleic fatty acids suppress short-term food intake in rats. Food & Function. PMID 32191234 DOI: 10.1039/c9fo02884f  0.499
2020 Cisbani G, Koppel A, Knezevic D, Suridjan I, Mizrahi R, Bazinet RP. Peripheral cytokine and fatty acid associations with neuroinflammation in AD and aMCI patients: an exploratory study. Brain, Behavior, and Immunity. PMID 32135194 DOI: 10.1016/j.bbi.2020.02.014  0.303
2020 Best LM, Williams B, Le Foll B, Mansouri E, Bazinet RP, Lin L, De Luca V, Lagzdins D, Rusjan P, Tyndale RF, Wilson AA, Hendershot CS, Heilig M, Houle S, Tong J, et al. Lower brain fatty acid amide hydrolase in treatment-seeking patients with alcohol use disorder: a positron emission tomography study with [C-11]CURB. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31910433 DOI: 10.1038/S41386-020-0606-2  0.461
2020 Gaudette E, Watling S, Warsh J, McCluskey T, Tong J, Houle S, Rusjan PM, Rhind SG, Bazinet R, Tyndale RF, Richardson JD, Hill MN, Jelty R, Kish S, Boileau I. Endocannabinoid Metabolism in Posttraumatic Stress Disorder: Results From a Neuroimaging Study With the Novel Fatty Acid Amide Hydrolase Probe, [C-11] Curb Biological Psychiatry. 87: S282-S283. DOI: 10.1016/J.Biopsych.2020.02.729  0.425
2019 Metherel AH, Lacombe RJS, Chouinard-Watkins R, Bazinet RP. Erratum: Docosahexaenoic acid is both a product of and a precursor to tetracosahexaenoic acid in the rat. Journal of Lipid Research. 60: 2102. PMID 31792023 DOI: 10.1194/jlr.ERR119000440  0.353
2019 Metherel AH, Harris WS, Ge L, Gibson RA, Chouinard-Watkins R, Bazinet RP, Liu L, Brenna JT, Aristizabal-Henao JJ, Stark KD, Block RC. Interlaboratory Assessment of Dried Blood Spot Fatty Acid Compositions. Lipids. PMID 31782523 DOI: 10.1002/Lipd.12203  0.451
2019 Alashmali SM, Lin L, Trépanier MO, Cisbani G, Bazinet RP. The effects of n-6 polyunsaturated fatty acid deprivation on the inflammatory gene response to lipopolysaccharide in the mouse hippocampus. Journal of Neuroinflammation. 16: 237. PMID 31775778 DOI: 10.1186/s12974-019-1615-0  0.591
2019 Lacombe RJS, Lee CC, Bazinet R. Turnover of brain DHA in mice is accurately determined by tracer-free natural abundance carbon isotope ratio analysis. Journal of Lipid Research. PMID 31712249 DOI: 10.1194/jlr.D119000518  0.463
2019 Otoki Y, Metherel AH, Pedersen T, Yang J, Hammock BD, Bazinet RP, Newman JW, Taha AY. Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. Lipids. PMID 31691988 DOI: 10.1002/Lipd.12197  0.467
2019 Metherel AH, Bazinet RP. Updates to the n-3 polyunsaturated fatty acid biosynthesis pathway: DHA synthesis rates, tetracosahexaenoic acid and (minimal) retroconversion. Progress in Lipid Research. 101008. PMID 31626820 DOI: 10.1016/j.plipres.2019.101008  0.433
2019 Santaren ID, Bazinet RP, Liu Z, Johnston LW, Sievenpiper JL, Giacca A, Retnakaran R, Harris SB, Zinman B, Hanley AJ. The Distribution of Fatty Acid Biomarkers of Dairy Intake across Serum Lipid Fractions: The Prospective Metabolism and Islet Cell Evaluation (PROMISE) Cohort. Lipids. PMID 31429083 DOI: 10.1002/Lipd.12185  0.3
2019 Bazinet RP, Metherel AH, Chen CT, Raza Shaikh S, Nadjar A, Joffre C, Layé S. Brain eicosapentaenoic acid metabolism as a lead for novel therapeutics in major depression. Brain, Behavior, and Immunity. PMID 31278982 DOI: 10.1016/J.Bbi.2019.07.001  0.431
2019 Yang B, Lin L, Bazinet RP, Chien YC, Chang JP, Satyanarayanan SK, Su H, Su KP. Clinical Efficacy and Biological Regulations of ω-3 PUFA-Derived Endocannabinoids in Major Depressive Disorder. Psychotherapy and Psychosomatics. 1-10. PMID 31269506 DOI: 10.1159/000501158  0.447
2019 Pitino MA, Alashmali SM, Hopperton KE, Unger S, Pouliot Y, Doyen A, O'Connor DL, Bazinet RP. Oxylipin concentration, but not fatty acid composition, is altered in human donor milk pasteurized using both thermal and non-thermal techniques. The British Journal of Nutrition. 1-21. PMID 31006410 DOI: 10.1017/S0007114519000916  0.373
2019 Bazinet RP, Bernoud-Hubac N, Lagarde M. How the plasma lysophospholipid and unesterified fatty acid pools supply the brain with docosahexaenoic acid. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 142: 1-3. PMID 30773208 DOI: 10.1016/j.plefa.2018.12.003  0.509
2019 Chouinard-Watkins R, Lacombe RJS, Metherel AH, Masoodi M, Bazinet RP. DHA Esterified to Phosphatidylserine or Phosphatidylcholine is More Efficient at Targeting the Brain than DHA Esterified to Triacylglycerol. Molecular Nutrition & Food Research. e1801224. PMID 30768751 DOI: 10.1002/mnfr.201801224  0.535
2019 Metherel AH, Irfan M, Chouinard-Watkins R, Trépanier MO, Stark KD, Bazinet RP. DHA Cycling Halves the DHA Supplementation Needed to Maintain Blood and Tissue Concentrations via Higher Synthesis from ALA in Long-Evans Rats. The Journal of Nutrition. PMID 30715388 DOI: 10.1093/jn/nxy282  0.408
2018 Taha AY, Trepanier MO, Coibanu FA, Saxena A, Jeffrey MA, Taha NMY, Burnham WM, Bazinet RP. Dietary Omega-3 Polyunsaturated Fatty Acid Deprivation Does Not Alter Seizure Thresholds but May Prevent the Anti-seizure Effects of Injected Docosahexaenoic Acid in Rats. Frontiers in Neurology. 9: 1188. PMID 30804888 DOI: 10.3389/fneur.2018.01188  0.318
2018 Hennebelle M, Metherel AH, Kitson AP, Otoki Y, Yang J, Lee KSS, Hammock BD, Bazinet RP, Taha AY. Brain oxylipin concentrations following hypercapnia / ischemia: effects of brain dissection and dissection time. Journal of Lipid Research. PMID 30463986 DOI: 10.1194/Jlr.D084228  0.343
2018 Chouinard-Watkins R, Bazinet RP. ACSL6 is critical for maintaining brain DHA levels. Proceedings of the National Academy of Sciences of the United States of America. PMID 30446610 DOI: 10.1073/pnas.1817557115  0.386
2018 Lin L, Metherel AH, Kitson AP, Alashmali SM, Hopperton KE, Trépanier MO, Jones PJ, Bazinet RP. Dietary fatty acids augment tissue levels of n-acylethanolamines in n-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) knockout mice. The Journal of Nutritional Biochemistry. 62: 134-142. PMID 30290332 DOI: 10.1016/j.jnutbio.2018.08.015  0.548
2018 Giuliano V, Scott Lacombe RJ, Hopperton KE, Bazinet RP. Applying stable carbon isotopic analysis at the natural abundance level to determine the origin of docosahexaenoic acid in the brain of the fat-1 mouse. Biochimica Et Biophysica Acta. PMID 30075211 DOI: 10.1016/j.bbalip.2018.07.014  0.581
2018 Lin YH, Hibbeln JR, Domenichiello AF, Ramsden CE, Salem NM, Chen CT, Jin H, Courville AB, Majchrzak-Hong SF, Rapoport SI, Bazinet RP, Miller BV. Quantitation of Human Whole-Body Synthesis-Secretion Rates of Docosahexaenoic Acid and Eicosapentaenoate Acid from Circulating Unesterified α-Linolenic Acid at Steady State. Lipids. PMID 30074625 DOI: 10.1002/Lipd.12055  0.369
2018 Johnston LW, Liu Z, Retnakaran R, Zinman B, Giacca A, Harris SB, Bazinet RP, Hanley AJ. Clusters of fatty acids in the serum triacylglyceride fraction associate with the disorders of type 2 diabetes. Journal of Lipid Research. PMID 29986954 DOI: 10.1194/Jlr.P084970  0.309
2018 Lacombe RJS, Giuliano V, Chouinard-Watkins R, Bazinet RP. Natural Abundance Carbon Isotopic Analysis Indicates the Equal Contribution of Local Synthesis and Plasma Uptake to Palmitate Levels in the Mouse Brain. Lipids. PMID 29923600 DOI: 10.1002/lipd.12046  0.467
2018 Trépanier MO, Hopperton KE, Giuliano V, Masoodi M, Bazinet RP. Increased brain docosahexaenoic acid has no effect on the resolution of neuroinflammation following intracerebroventricular lipopolysaccharide injection. Neurochemistry International. PMID 29792954 DOI: 10.1016/j.neuint.2018.05.010  0.428
2018 Trépanier MO, Hildebrand KD, Nyamoya SD, Amor S, Bazinet RP, Kipp M. Phosphatidylcholine 36:1 concentration decreases along with demyelination in the cuprizone animal model and post-mortem of multiple sclerosis brain tissue. Journal of Neurochemistry. PMID 29574981 DOI: 10.1111/jnc.14335  0.464
2018 Lacombe RJS, Chouinard-Watkins R, Bazinet RP. Brain docosahexaenoic acid uptake and metabolism. Molecular Aspects of Medicine. PMID 29305120 DOI: 10.1016/j.mam.2017.12.004  0.526
2018 Layé S, Nadjar A, Joffre C, Bazinet RP. Anti-Inflammatory Effects of Omega-3 Fatty Acids in the Brain: Physiological Mechanisms and Relevance to Pharmacology. Pharmacological Reviews. 70: 12-38. PMID 29217656 DOI: 10.1124/pr.117.014092  0.563
2018 Gabrielson D, Bazinet R, Brezden-Masley C, Keith M, Darling P. Nutritional, Inflammatory, and Fatty Acid Status in Gastrointestinal Cancer Journal of the Academy of Nutrition and Dietetics. 118. DOI: 10.1016/J.Jand.2018.06.274  0.439
2018 Best LM, Hendershot CS, Samantha J, Tong J, Le Foll B, Houle S, Tyndale RF, Bazinet R, Kish S, Boileau I. S265. Endocannabinoid Metabolism and Alcohol Consumption in Youth: A PET Study With the Fatty Acid Amide Hydrolase Radioligand [11C]CURB Biological Psychiatry. 83: S451. DOI: 10.1016/J.Biopsych.2018.02.1157  0.361
2018 Boileau I, Westwood D, Richardson D, Rhind S, Tyndale RF, Lanius R, Bazinet R, Lobaugh NJ, Houle S. 51. Investigating Endocannabinoid Mechanisms in Posttraumatic Stress Disorder: Neuroimaging Studies With the Novel Fatty Acid Amide Hydrolase Probe, [11C]CURB Biological Psychiatry. 83: S21. DOI: 10.1016/J.Biopsych.2018.02.068  0.432
2017 Metherel AH, Lacombe RJS, Chouinard-Watkins RE, Hopperton KE, Bazinet RP. Complete assessment of whole-body n-3 and n-6 PUFA synthesis-secretion kinetics and DHA turnover in a rodent model. Journal of Lipid Research. PMID 29229739 DOI: 10.1194/jlr.M081380  0.359
2017 Chouinard-Watkins R, Lacombe RJS, Bazinet RP. Mechanisms regulating brain docosahexaenoic acid uptake: what is the recent evidence? Current Opinion in Clinical Nutrition and Metabolic Care. PMID 29206690 DOI: 10.1097/MCO.0000000000000440  0.537
2017 Hopperton KE, James NCE, Mohammad D, Irfan M, Bazinet RP. Dietary fish oil, and to a lesser extent the fat-1 transgene, increases astrocyte activation in response to intracerebroventricular amyloid-β 1-40 in mice. Nutritional Neuroscience. 1-7. PMID 29113539 DOI: 10.1080/1028415X.2017.1396068  0.447
2017 Hopperton KE, Trépanier MO, James NCE, Chouinard-Watkins R, Bazinet RP. Fish oil feeding attenuates neuroinflammatory gene expression without concomitant changes in brain eicosanoids and docosanoids in a mouse model of Alzheimer's disease. Brain, Behavior, and Immunity. PMID 29109025 DOI: 10.1016/j.bbi.2017.11.002  0.478
2017 Metherel AH, Kitson AP, Domenichiello AF, Lacombe RJS, Hopperton KE, Trépanier MO, Alashmali SM, Lin L, Bazinet RP. Docosahexaenoic acid (DHA) accretion in the placenta but not the fetus is matched by plasma unesterified DHA uptake rates in pregnant Long Evans rats. Placenta. 58: 90-97. PMID 28962703 DOI: 10.1016/j.placenta.2017.08.072  0.398
2017 Alashmali SM, Kitson AP, Lin L, Lacombe RJS, Bazinet RP. Maternal dietary n-6 polyunsaturated fatty acid deprivation does not exacerbate post-weaning reductions in arachidonic acid and its mediators in the mouse hippocampus. Nutritional Neuroscience. 1-12. PMID 28903622 DOI: 10.1080/1028415X.2017.1372160  0.568
2017 Chouinard-Watkins R, Chen CT, Metherel AH, Lacombe RJS, Thies F, Masoodi M, Bazinet RP. Phospholipid class-specific brain enrichment in response to lysophosphatidylcholine docosahexaenoic acid infusion. Biochimica Et Biophysica Acta. 1862: 1092-1098. PMID 28760485 DOI: 10.1016/j.bbalip.2017.07.013  0.471
2017 Lacombe RJS, Giuliano V, Colombo SM, Arts MT, Bazinet RP. Compound specific isotope analysis resolves the dietary origin of docosahexaenoic acid (DHA) in the mouse brain. Journal of Lipid Research. PMID 28694298 DOI: 10.1194/jlr.D077990  0.501
2017 Hennebelle M, Zhang Z, Metherel AH, Kitson AP, Otoki Y, Richardson CE, Yang J, Lee KSS, Hammock BD, Zhang L, Bazinet RP, Taha AY. Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. Scientific Reports. 7: 4342. PMID 28659576 DOI: 10.1038/S41598-017-02914-7  0.451
2017 Metherel AH, Kitson AP, Domenichiello AF, Lacombe RJS, Hopperton KE, Trépanier MO, Alashmali SM, Lin L, Bazinet RP. Maternal liver docosahexaenoic acid (DHA) stores are increased via higher serum unesterified DHA uptake in pregnant long Evans rats. The Journal of Nutritional Biochemistry. 46: 143-150. PMID 28628798 DOI: 10.1016/j.jnutbio.2017.05.011  0.429
2017 Islam R, Trépanier MO, Milenkovic M, Horsfall W, Salahpour A, Bazinet RP, Ramsey AJ. Vulnerability to omega-3 deprivation in a mouse model of NMDA receptor hypofunction. Npj Schizophrenia. 3: 12. PMID 28560258 DOI: 10.1038/s41537-017-0014-8  0.43
2017 Lin L, Metherel AH, Jones PJ, Bazinet RP. Fatty acid amide hydrolase (FAAH) regulates hypercapnia/ischemia-induced increases in n-acylethanolamines in mouse brain. Journal of Neurochemistry. PMID 28488728 DOI: 10.1111/jnc.14067  0.548
2017 Best L, Tong J, Le Foll B, Bazinet R, Tyndale RF, Mizrahi R, Lobaugh NJ, Houle S, Kish S, Boileau I. 619. Brain Levels of Fatty Acid Amide Hydrolase Are Not Altered in Overweight Healthy Individuals: A Pilot PET Study with [11C]CURB Biological Psychiatry. 81: S250-S251. DOI: 10.1016/J.Biopsych.2017.02.489  0.534
2016 Metherel AH, Domenichiello AF, Kitson AP, Lin YH, Bazinet RP. Serum n-3 Tetracosapentaenoic Acid and Tetracosahexaenoic Acid Increase Following Higher Dietary α-Linolenic Acid but not Docosahexaenoic Acid. Lipids. PMID 28005226 DOI: 10.1007/s11745-016-4223-0  0.425
2016 Lee HJ, Rao JS, Ertley RN, Chang L, Rapoport SI, Bazinet RP. Retraction note to: Chronic fluoxetine increases cytosolic phospholipase A2 activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat. Psychopharmacology. PMID 27999922 DOI: 10.1007/S00213-016-4499-Z  0.387
2016 Domenichiello AF, Kitson AP, Metherel AH, Chen CT, Hopperton KE, Stavro PM, Bazinet RP. Whole-Body Docosahexaenoic Acid Synthesis-Secretion Rates in Rats Are Constant across a Large Range of Dietary α-Linolenic Acid Intakes. The Journal of Nutrition. PMID 27852871 DOI: 10.3945/jn.116.232074  0.531
2016 Hopperton KE, Trépanier MO, Giuliano V, Bazinet RP. Brain omega-3 polyunsaturated fatty acids modulate microglia cell number and morphology in response to intracerebroventricular amyloid-β 1-40 in mice. Journal of Neuroinflammation. 13: 257. PMID 27688126 DOI: 10.1186/s12974-016-0721-5  0.416
2016 Metherel AH, Domenichiello AF, Kitson AP, Hopperton KE, Bazinet RP. Whole-body DHA synthesis-secretion kinetics from plasma eicosapentaenoic acid and alpha-linolenic acid in the free-living rat. Biochimica Et Biophysica Acta. PMID 27263420 DOI: 10.1016/j.bbalip.2016.05.014  0.342
2016 Kitson AP, Metherel AH, Chen CT, Domenichiello AF, Trépanier MO, Berger A, Bazinet RP. Effect of dietary docosahexaenoic acid (DHA) in phospholipids or triglycerides on brain DHA uptake and accretion. The Journal of Nutritional Biochemistry. 33: 91-102. PMID 27135386 DOI: 10.1016/j.jnutbio.2016.02.009  0.45
2016 Domenichiello AF, Kitson AP, Chen CT, Trépanier MO, Stavro PM, Bazinet RP. The effect of linoleic acid on the whole body synthesis rates of polyunsaturated fatty acids from α-linolenic acid and linoleic acid in free-living rats. The Journal of Nutritional Biochemistry. 30: 167-76. PMID 27012633 DOI: 10.1016/j.jnutbio.2015.11.016  0.437
2016 Alashmali SM, Hopperton KE, Bazinet RP. Lowering dietary n-6 polyunsaturated fatty acids: interaction with brain arachidonic and docosahexaenoic acids. Current Opinion in Lipidology. 27: 54-66. PMID 26709472 DOI: 10.1097/MOL.0000000000000255  0.567
2015 Chen CT, Kitson AP, Hopperton KE, Domenichiello AF, Trépanier MO, Lin LE, Ermini L, Post M, Thies F, Bazinet RP. Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain. Scientific Reports. 5: 15791. PMID 26511533 DOI: 10.1038/Srep15791  0.423
2015 Trépanier MO, Hopperton KE, Orr SK, Bazinet RP. N-3 polyunsaturated fatty acids in animal models with neuroinflammation: An update. European Journal of Pharmacology. PMID 26036964 DOI: 10.1016/J.Ejphar.2015.05.045  0.744
2015 Domenichiello AF, Kitson AP, Bazinet RP. Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain? Progress in Lipid Research. 59: 54-66. PMID 25920364 DOI: 10.1016/j.plipres.2015.04.002  0.46
2015 Lin LE, Chen CT, Hildebrand KD, Liu Z, Hopperton KE, Bazinet RP. Chronic dietary n-6 PUFA deprivation leads to conservation of arachidonic acid and more rapid loss of DHA in rat brain phospholipids. Journal of Lipid Research. 56: 390-402. PMID 25477531 DOI: 10.1194/jlr.M055590  0.489
2015 Chen CT, Bazinet RP. β-oxidation and rapid metabolism, but not uptake regulate brain eicosapentaenoic acid levels. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 92: 33-40. PMID 24986271 DOI: 10.1016/j.plefa.2014.05.007  0.483
2014 Bazinet RP, Layé S. Polyunsaturated fatty acids and their metabolites in brain function and disease. Nature Reviews. Neuroscience. 15: 771-85. PMID 25387473 DOI: 10.1038/nrn3820  0.56
2014 Mason JK, Kharotia S, Wiggins AK, Kitson AP, Chen J, Bazinet RP, Thompson LU. 17β-estradiol increases liver and serum docosahexaenoic acid in mice fed varying levels of α-linolenic acid. Lipids. 49: 745-56. PMID 24913495 DOI: 10.1007/S11745-014-3913-8  0.389
2014 Trépanier MO, Lim J, Lai TK, Cho HJ, Domenichiello AF, Chen CT, Taha AY, Bazinet RP, Burnham WM. Intraperitoneal administration of docosahexaenoic acid for 14days increases serum unesterified DHA and seizure latency in the maximal pentylenetetrazol model. Epilepsy & Behavior : E&B. 33: 138-43. PMID 24662925 DOI: 10.1016/j.yebeh.2014.02.020  0.341
2014 Chen CT, Trépanier MO, Hopperton KE, Domenichiello AF, Masoodi M, Bazinet RP. Inhibiting mitochondrial β-oxidation selectively reduces levels of nonenzymatic oxidative polyunsaturated fatty acid metabolites in the brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 376-9. PMID 24326387 DOI: 10.1038/jcbfm.2013.221  0.332
2014 Bazinet RP, Chu MW. Omega-6 polyunsaturated fatty acids: is a broad cholesterol-lowering health claim appropriate? Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 186: 434-9. PMID 24218530 DOI: 10.1503/cmaj.130253  0.346
2014 Domenichiello AF, Chen CT, Trepanier MO, Stavro PM, Bazinet RP. Whole body synthesis rates of DHA from α-linolenic acid are greater than brain DHA accretion and uptake rates in adult rats. Journal of Lipid Research. 55: 62-74. PMID 24212299 DOI: 10.1194/jlr.M042275  0.452
2014 Hopperton KE, Duncan RE, Bazinet RP, Archer MC. Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity. Experimental Cell Research. 320: 302-10. PMID 24200503 DOI: 10.1016/j.yexcr.2013.10.016  0.329
2014 Trépanier M, Taha AY, Bazinet RP, Burnham W. 1. Daily DHA injections raise seizure thresholds and blood but not brain free DHA levels in rats Clinical Neurophysiology. 125: e9. DOI: 10.1016/j.clinph.2013.09.014  0.403
2013 Taha AY, Zahid T, Epps T, Trepanier MO, Burnham WM, Bazinet RP, Zhang L. Selective reduction of excitatory hippocampal sharp waves by docosahexaenoic acid and its methyl ester analog ex-vivo. Brain Research. 1537: 9-17. PMID 24036166 DOI: 10.1016/j.brainres.2013.09.004  0.377
2013 Orr SK, Palumbo S, Bosetti F, Mount HT, Kang JX, Greenwood CE, Ma DW, Serhan CN, Bazinet RP. Unesterified docosahexaenoic acid is protective in neuroinflammation. Journal of Neurochemistry. 127: 378-93. PMID 23919613 DOI: 10.1111/Jnc.12392  0.771
2013 Chen CT, Domenichiello AF, Trépanier MO, Liu Z, Masoodi M, Bazinet RP. The low levels of eicosapentaenoic acid in rat brain phospholipids are maintained via multiple redundant mechanisms. Journal of Lipid Research. 54: 2410-22. PMID 23836105 DOI: 10.1194/jlr.M038505  0.471
2013 Orr SK, Trépanier MO, Bazinet RP. n-3 Polyunsaturated fatty acids in animal models with neuroinflammation. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 88: 97-103. PMID 22770766 DOI: 10.1016/J.Plefa.2012.05.008  0.756
2013 Trepanier MO, Taha A, Bazinet R, Burnham M. 1. The anticonvulsant effects of n-3 PUFA: Animal studies Clinical Neurophysiology. 124: e5. DOI: 10.1016/J.Clinph.2012.08.029  0.308
2012 Ramadeen A, Connelly KA, Leong-Poi H, Hu X, Fujii H, Laurent G, Domenichiello AF, Bazinet RP, Dorian P. Docosahexaenoic acid, but not eicosapentaenoic acid, supplementation reduces vulnerability to atrial fibrillation. Circulation. Arrhythmia and Electrophysiology. 5: 978-83. PMID 22923273 DOI: 10.1161/CIRCEP.112.971515  0.336
2012 Arsenault D, Julien C, Chen CT, Bazinet RP, Calon F. Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in mice. Journal of Neurochemistry. 122: 427-43. PMID 22551210 DOI: 10.1111/j.1471-4159.2012.07772.x  0.404
2012 Ramadeen A, Connelly KA, Leong-Poi H, Hu X, Fujii H, Van Krieken R, Laurent G, Holub BJ, Bazinet RP, Dorian P. N-3 polyunsaturated fatty acid supplementation does not reduce vulnerability to atrial fibrillation in remodeling atria. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 1115-1122.e4. PMID 22342864 DOI: 10.1016/j.hrthm.2012.02.013  0.348
2011 Chen CT, Liu Z, Bazinet RP. Rapid de-esterification and loss of eicosapentaenoic acid from rat brain phospholipids: an intracerebroventricular study. Journal of Neurochemistry. 116: 363-73. PMID 21091476 DOI: 10.1111/j.1471-4159.2010.07116.x  0.48
2010 Song BJ, Elbert A, Rahman T, Orr SK, Chen CT, Febbraio M, Bazinet RP. Genetic ablation of CD36 does not alter mouse brain polyunsaturated fatty acid concentrations. Lipids. 45: 291-9. PMID 20306148 DOI: 10.1007/S11745-010-3398-Z  0.753
2010 Orr SK, Tong JY, Kang JX, Ma DW, Bazinet RP. The fat-1 mouse has brain docosahexaenoic acid levels achievable through fish oil feeding. Neurochemical Research. 35: 811-9. PMID 20177777 DOI: 10.1007/S11064-010-0139-X  0.726
2010 Duncan RE, Bazinet RP. Brain arachidonic acid uptake and turnover: implications for signaling and bipolar disorder. Current Opinion in Clinical Nutrition and Metabolic Care. 13: 130-8. PMID 20145439 DOI: 10.1097/MCO.0b013e328336b615  0.537
2010 Rahman T, Taha AY, Song BJ, Orr SK, Liu Z, Chen CT, Bazinet RP. The very low density lipoprotein receptor is not necessary for maintaining brain polyunsaturated fatty acid concentrations. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 82: 141-5. PMID 20106645 DOI: 10.1016/J.Plefa.2009.11.003  0.743
2010 Boudrault C, Bazinet RP, Kang JX, Ma DW. Cyclooxygenase-2 and n-6 PUFA are lower and DHA is higher in the cortex of fat-1 mice. Neurochemistry International. 56: 585-9. PMID 20064570 DOI: 10.1016/j.neuint.2009.12.022  0.478
2010 Lee HJ, Bazinet RP, Rapoport SI, Bhattacharjee AK. Brain arachidonic acid cascade enzymes are upregulated in a rat model of unilateral Parkinson disease. Neurochemical Research. 35: 613-9. PMID 19997776 DOI: 10.1007/S11064-009-0106-6  0.301
2010 Bazinet RP. Aspirin, arachidonic acid and the regulation of mood. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 82: 7-8. PMID 19910174 DOI: 10.1016/j.plefa.2009.10.008  0.387
2010 Green JT, Liu Z, Bazinet RP. Brain phospholipid arachidonic acid half-lives are not altered following 15 weeks of N-3 polyunsaturated fatty acid adequate or deprived diet. Journal of Lipid Research. 51: 535-43. PMID 19661256 DOI: 10.1194/jlr.M000786  0.489
2009 Bazinet RP. Is the brain arachidonic acid cascade a common target of drugs used to manage bipolar disorder? Biochemical Society Transactions. 37: 1104-9. PMID 19754461 DOI: 10.1042/BST0371104  0.495
2009 Ouellet M, Emond V, Chen CT, Julien C, Bourasset F, Oddo S, LaFerla F, Bazinet RP, Calon F. Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood-brain barrier: An in situ cerebral perfusion study. Neurochemistry International. 55: 476-82. PMID 19442696 DOI: 10.1016/J.Neuint.2009.04.018  0.453
2009 Chen CT, Liu Z, Ouellet M, Calon F, Bazinet RP. Rapid beta-oxidation of eicosapentaenoic acid in mouse brain: an in situ study. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 80: 157-63. PMID 19237271 DOI: 10.1016/j.plefa.2009.01.005  0.49
2008 Chen CT, Green JT, Orr SK, Bazinet RP. Regulation of brain polyunsaturated fatty acid uptake and turnover. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 79: 85-91. PMID 18938067 DOI: 10.1016/J.Plefa.2008.09.003  0.771
2008 Milligan LA, Bazinet RP. Evolutionary modifications of human milk composition: evidence from long-chain polyunsaturated fatty acid composition of anthropoid milks. Journal of Human Evolution. 55: 1086-95. PMID 18809203 DOI: 10.1016/J.Jhevol.2008.07.010  0.462
2008 Orr SK, Bazinet RP. The emerging role of docosahexaenoic acid in neuroinflammation. Current Opinion in Investigational Drugs (London, England : 2000). 9: 735-43. PMID 18600579  0.77
2008 Rao JS, Lee HJ, Rapoport SI, Bazinet RP. Mode of action of mood stabilizers: is the arachidonic acid cascade a common target? Molecular Psychiatry. 13: 585-96. PMID 18347600 DOI: 10.1038/mp.2008.31  0.371
2008 Green JT, Orr SK, Bazinet RP. The emerging role of group VI calcium-independent phospholipase A2 in releasing docosahexaenoic acid from brain phospholipids. Journal of Lipid Research. 49: 939-44. PMID 18252846 DOI: 10.1194/Jlr.R700017-Jlr200  0.732
2008 Lee HJ, Rao JS, Chang L, Rapoport SI, Bazinet RP. Chronic N-methyl-D-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat. Journal of Lipid Research. 49: 162-8. PMID 17957090 DOI: 10.1194/Jlr.M700406-Jlr200  0.488
2008 Chen CT, Ma DW, Kim JH, Mount HT, Bazinet RP. The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations. Journal of Lipid Research. 49: 147-52. PMID 17932396 DOI: 10.1194/jlr.M700386-JLR200  0.54
2008 Milligan LA, Rapoport SI, Cranfield MR, Dittus W, Glander KE, Oftedal OT, Power ML, Whittier CA, Bazinet RP. Fatty acid composition of wild anthropoid primate milks. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 149: 74-82. PMID 17916436 DOI: 10.1016/J.Cbpb.2007.08.006  0.445
2007 Lee HJ, Rao JS, Rapoport SI, Bazinet RP. Antimanic therapies target brain arachidonic acid signaling: lessons learned about the regulation of brain fatty acid metabolism. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 77: 239-46. PMID 18042366 DOI: 10.1016/J.Plefa.2007.10.018  0.562
2007 Lee HJ, Rao JS, Chang L, Rapoport SI, Bazinet RP. Chronic lamotrigine does not alter the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat: implications for the treatment of bipolar disorder. Psychopharmacology. 193: 467-74. PMID 17487474 DOI: 10.1007/S00213-007-0803-2  0.457
2007 Milligan LA, Bazinet RP. Is docosahexaenoic acid a red herring for the aquatic diet?--Comments by Milligan and Bazinet. The British Journal of Nutrition. 97: 1023-4; discussion 1. PMID 17408532 DOI: 10.1017/S0007114507669232  0.354
2007 Lee HJ, Rao JS, Ertley RN, Chang L, Rapoport SI, Bazinet RP. Chronic fluoxetine increases cytosolic phospholipase A(2) activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat. Psychopharmacology. 190: 103-15. PMID 17093977 DOI: 10.1007/S00213-006-0582-1  0.371
2007 Rao JS, Ertley RN, DeMar JC, Rapoport SI, Bazinet RP, Lee HJ. Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex. Molecular Psychiatry. 12: 151-7. PMID 16983392 DOI: 10.1038/sj.mp.4001887  0.437
2007 Rao JS, Ertley RN, Lee HJ, DeMar JC, Arnold JT, Rapoport SI, Bazinet RP. n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. Molecular Psychiatry. 12: 36-46. PMID 16983391 DOI: 10.1038/sj.mp.4001888  0.371
2007 Bazinet RP, Bhattacharjee AK, Lee HJ. Haloperidol targets brain arachidonic acid signaling. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 314-5; author reply . PMID 16797815 DOI: 10.1016/j.pnpbp.2006.03.038  0.463
2007 Pillai VC, Bazinet RP, Rapoport SI, Weis MT. Identification and characterisation of substrate requirements for brain long chain fatty acyl CoA synthase (LCAFCoAS) isoforms The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A607-A  0.386
2006 DeMar JC, Lee HJ, Ma K, Chang L, Bell JM, Rapoport SI, Bazinet RP. Brain elongation of linoleic acid is a negligible source of the arachidonate in brain phospholipids of adult rats. Biochimica Et Biophysica Acta. 1761: 1050-9. PMID 16920015 DOI: 10.1016/J.Bbalip.2006.06.006  0.433
2006 Lee HJ, Mayette J, Rapoport SI, Bazinet RP. Selective remodeling of cardiolipin fatty acids in the aged rat heart. Lipids in Health and Disease. 5: 2. PMID 16430781 DOI: 10.1186/1476-511X-5-2  0.38
2006 Bazinet RP, Weis MT, Rapoport SI, Rosenberger TA. Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder. Psychopharmacology. 184: 122-9. PMID 16344985 DOI: 10.1007/S00213-005-0272-4  0.534
2006 Bazinet RP, Rao JS, Chang L, Rapoport SI, Lee HJ. Chronic carbamazepine decreases the incorporation rate and turnover of arachidonic acid but not docosahexaenoic acid in brain phospholipids of the unanesthetized rat: relevance to bipolar disorder. Biological Psychiatry. 59: 401-7. PMID 16182257 DOI: 10.1016/J.Biopsych.2005.07.024  0.507
2005 Lee HJ, Ghelardoni S, Chang L, Bosetti F, Rapoport SI, Bazinet RP. Topiramate does not alter the kinetics of arachidonic or docosahexaenoic acid in brain phospholipids of the unanesthetized rat. Neurochemical Research. 30: 677-83. PMID 16176072 DOI: 10.1007/S11064-005-2756-3  0.477
2005 Bazinet RP, Lee HJ, Felder CC, Porter AC, Rapoport SI, Rosenberger TA. Rapid high-energy microwave fixation is required to determine the anandamide (N-arachidonoylethanolamine) concentration of rat brain. Neurochemical Research. 30: 597-601. PMID 16176062 DOI: 10.1007/S11064-005-2746-5  0.405
2005 Bazinet RP, Rao JS, Chang L, Rapoport SI, Lee HJ. Chronic valproate does not alter the kinetics of docosahexaenoic acid within brain phospholipids of the unanesthetized rat. Psychopharmacology. 182: 180-5. PMID 15986187 DOI: 10.1007/S00213-005-0059-7  0.556
2005 Ghelardoni S, Bazinet RP, Rapoport SI, Bosetti F. Topiramate does not alter expression in rat brain of enzymes of arachidonic acid metabolism. Psychopharmacology. 180: 523-9. PMID 15719218 DOI: 10.1007/S00213-005-2189-3  0.386
Low-probability matches (unlikely to be authored by this person)
2003 Bazinet RP, McMillan EG, Cunnane SC. Dietary alpha-linolenic acid increases the n-3 PUFA content of sow's milk and the tissues of the suckling piglet. Lipids. 38: 1045-9. PMID 14669969  0.299
2016 Johnston LW, Harris SB, Retnakaran R, Zinman B, Giacca A, Liu Z, Bazinet RP, Hanley AJ. Longitudinal associations of phospholipid and cholesteryl ester fatty acids with disorders underlying diabetes. The Journal of Clinical Endocrinology and Metabolism. jc20154267. PMID 27144932 DOI: 10.1210/Jc.2015-4267  0.298
2018 Metherel AH, Lacombe RJS, Aristizabal Henao JJ, Morin-Rivron D, Kitson AP, Hopperton KE, Chalil D, Masoodi M, Stark KD, Bazinet RP. Two weeks of docosahexaenoic acid (DHA) supplementation increases synthesis-secretion kinetics of n-3 polyunsaturated fatty acids compared to 8 weeks of DHA supplementation. The Journal of Nutritional Biochemistry. 60: 24-34. PMID 30041049 DOI: 10.1016/j.jnutbio.2018.07.002  0.298
2017 Metherel AH, Chouinard-Watkins R, Trépanier MO, Lacombe RJS, Bazinet RP. Retroconversion is a minor contributor to increases in eicosapentaenoic acid following docosahexaenoic acid feeding as determined by compound specific isotope analysis in rat liver. Nutrition & Metabolism. 14: 75. PMID 29209405 DOI: 10.1186/s12986-017-0230-2  0.297
2003 Bazinet RP, Douglas H, Cunnane SC. Whole-body utilization of n-3 PUFA in n-6 PUFA-deficient rats. Lipids. 38: 187-9. PMID 12733752  0.295
2018 Metherel AH, Lacombe RJS, Chouinard-Watkins R, Bazinet RP. Docosahexaenoic acid is both a product of and a precursor to tetracosahexaenoic acid in the rat. Journal of Lipid Research. PMID 30573561 DOI: 10.1194/jlr.M090373  0.295
2023 Klievik BJ, Metherel AH, Cisbani G, Valenzuela R, Bazinet RP. Novel C enrichment technique reveals early turnover of DHA in peripheral tissues. Journal of Lipid Research. 64: 100357. PMID 36948271 DOI: 10.1016/j.jlr.2023.100357  0.29
2009 Boudrault C, Bazinet RP, Ma DW. Experimental models and mechanisms underlying the protective effects of n-3 polyunsaturated fatty acids in Alzheimer's disease. The Journal of Nutritional Biochemistry. 20: 1-10. PMID 18824343 DOI: 10.1016/j.jnutbio.2008.05.016  0.285
2022 Yehia NA, Lai KZH, Semnani-Azad Z, Blanco Mejia S, Bazinet RP, Beaudry JL, Hanley AJ. Association of branched chain fatty acids with cardiometabolic disorders in humans: a systematic review. Nutrition Reviews. PMID 36029228 DOI: 10.1093/nutrit/nuac051  0.283
2022 Lai KZH, Yehia NA, Semnani-Azad Z, Mejia SB, Boucher BA, Malik V, Bazinet RP, Hanley AJ. Lifestyle Factors Associated with Circulating Very Long-Chain Saturated Fatty Acids in Humans: A Systematic Review of Observational Studies. Advances in Nutrition (Bethesda, Md.). 14: 99-114. PMID 36811597 DOI: 10.1016/j.advnut.2022.10.004  0.283
2018 Scola G, Versace A, Metherel AH, Monsalve-Castro LA, Phillips ML, Bazinet RP, Andreazza AC. Alterations in peripheral fatty acid composition in bipolar and unipolar depression. Journal of Affective Disorders. PMID 29336895 DOI: 10.1016/J.Jad.2017.12.025  0.275
2012 Trépanier MO, Taha AY, Mantha RL, Ciobanu FA, Zeng QH, Tchkhartichvili GM, Domenichiello AF, Bazinet RP, Burnham WM. Increases in seizure latencies induced by subcutaneous docosahexaenoic acid are lost at higher doses. Epilepsy Research. 99: 225-32. PMID 22285511 DOI: 10.1016/j.eplepsyres.2011.12.001  0.272
2005 Bhattacharjee AK, Chang L, Lee HJ, Bazinet RP, Seemann R, Rapoport SI. D2 but not D1 dopamine receptor stimulation augments brain signaling involving arachidonic acid in unanesthetized rats. Psychopharmacology. 180: 735-42. PMID 16163535 DOI: 10.1007/S00213-005-2208-4  0.27
2006 Rao JS, Ertley RN, Lee HJ, Rapoport SI, Bazinet RP. Chronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortex. The Pharmacogenomics Journal. 6: 413-20. PMID 16636684 DOI: 10.1038/sj.tpj.6500391  0.267
2021 Hopperton KE, Pitino MA, Chouinard-Watkins R, Shama S, Sammut N, Bando N, Williams BA, Walton K, Kiss A, Unger SL, Bazinet RP, O'Connor DL. Determinants of fatty acid content and composition of human milk fed to infants born weighing <1250 g. The American Journal of Clinical Nutrition. PMID 34254983 DOI: 10.1093/ajcn/nqab222  0.264
2008 Bhattacharjee AK, Chang L, White L, Bazinet RP, Rapoport SI. Imaging apomorphine stimulation of brain arachidonic acid signaling via D2-like receptors in unanesthetized rats. Psychopharmacology. 197: 557-66. PMID 18274730 DOI: 10.1007/S00213-008-1073-3  0.263
2021 Yashpal S, Liese AD, Boucher BA, Wagenknecht LE, Haffner SM, Johnston LW, Bazinet RP, Rewers M, Rotter JI, Watkins SM, Hanley AJ. Metabolomic profiling of the Dietary Approaches to Stop Hypertension (DASH) diet provides novel insights for the nutritional epidemiology of type 2 diabetes mellitus (T2DM). The British Journal of Nutrition. 1-29. PMID 34511138 DOI: 10.1017/S0007114521003561  0.26
2008 Bhattacharjee AK, Chang L, Chen M, White L, Bell JM, Bazinet RP, Rapoport SI. Chronic d-amphetamine depresses an imaging marker of arachidonic acid metabolism in rat brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 957-69. PMID 18570702 DOI: 10.1017/S1461145708008833  0.258
2013 Taha AY, Trepanier MO, Ciobanu FA, Taha NM, Ahmed M, Zeng Q, Cheuk WI, Ip B, Filo E, Scott BW, Burnham WM, Bazinet RP. A minimum of 3 months of dietary fish oil supplementation is required to raise amygdaloid afterdischarge seizure thresholds in rats--implications for treating complex partial seizures. Epilepsy & Behavior : E&B. 27: 49-58. PMID 23376336 DOI: 10.1016/j.yebeh.2012.12.004  0.255
2022 Badewy R, Azarpazhooh A, Tenenbaum H, Connor KL, Lai JY, Sgro M, Bazinet RP, Fine N, Watson E, Sun C, Saha S, Glogauer M. The Association between Maternal Oral Inflammation and Neutrophil Phenotypes and Poly-Unsaturated Fatty Acids Composition in Human Milk: A Prospective Cohort Study. Cells. 11. PMID 36552874 DOI: 10.3390/cells11244110  0.252
2016 Trépanier MO, Eiden M, Morin-Rivron D, Bazinet RP, Masoodi M. High-resolution lipidomics coupled with rapid fixation reveals novel ischemia-induced signaling in the rat neurolipidome. Journal of Neurochemistry. PMID 28002627 DOI: 10.1111/jnc.13934  0.25
2019 Colombo SM, Rodgers TFM, Diamond ML, Bazinet RP, Arts MT. Projected declines in global DHA availability for human consumption as a result of global warming. Ambio. PMID 31512173 DOI: 10.1007/S13280-019-01234-6  0.247
2016 Trépanier MO, Hopperton KE, Mizrahi R, Mechawar N, Bazinet RP. Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review. Molecular Psychiatry. 21: 1009-26. PMID 27271499 DOI: 10.1038/Mp.2016.90  0.242
2016 Lewis E, Perkins B, Lovblom E, Bazinet R, Wolever T, Bril V. One Year of Seal Oil Omega-3 Supplementation Stops the Progression of Diabetic Sensorimotor Polyneuropathy: Results from a Clinical Pilot Trial Canadian Journal of Diabetes. 40: S73. DOI: 10.1016/J.Jcjd.2016.08.212  0.241
2006 Bhattacharjee AK, Chang L, White L, Bazinet RP, Rapoport SI. D-Amphetamine stimulates D2 dopamine receptor-mediated brain signaling involving arachidonic acid in unanesthetized rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 1378-88. PMID 16511499 DOI: 10.1038/Sj.Jcbfm.9600290  0.234
2009 Taha AY, Chen CT, Liu Z, Kim JH, Mount HT, Bazinet RP. Brainstem concentrations of cholesterol are not influenced by genetic ablation of the low-density lipoprotein receptor. Neurochemical Research. 34: 311-5. PMID 18607722 DOI: 10.1007/s11064-008-9777-7  0.234
2022 Umaru BA, Kagawa Y, Ohsaki Y, Pan Y, Chen CT, Chen DK, Abe T, Shil SK, Miyazaki H, Kobayashi S, Maekawa M, Yamamoto Y, Wannakul T, Yang S, Bazinet RP, et al. Oleic acid-bound FABP7 drives glioma cell proliferation through regulation of nuclear lipid droplet formation. The Febs Journal. PMID 36325660 DOI: 10.1111/febs.16672  0.23
2008 Lee HJ, Ertley RN, Rapoport SI, Bazinet RP, Rao JS. Chronic administration of lamotrigine downregulates COX-2 mRNA and protein in rat frontal cortex. Neurochemical Research. 33: 861-6. PMID 18080190 DOI: 10.1007/S11064-007-9526-3  0.227
2007 Rao JS, Bazinet RP, Rapoport SI, Lee HJ. Chronic treatment of rats with sodium valproate downregulates frontal cortex NF-kappaB DNA binding activity and COX-2 mRNA. Bipolar Disorders. 9: 513-20. PMID 17680922 DOI: 10.1111/J.1399-5618.2007.00361.X  0.226
2003 Bazinet RP, McMillan EG, Seebaransingh R, Hayes AM, Cunnane SC. Whole-body beta-oxidation of 18:2omega6 and 18:3omega3 in the pig varies markedly with weaning strategy and dietary 18:3omega3. Journal of Lipid Research. 44: 314-9. PMID 12576513 DOI: 10.1194/jlr.M200153-JLR200  0.223
2020 Lewis EJH, Lovblom LE, Cisbani G, Chen DK, Bazinet RP, Wolever TMS, Perkins BA, Bril V. Baseline omega-3 level is associated with nerve regeneration following 12-months of omega-3 nutrition therapy in patients with type 1 diabetes. Journal of Diabetes and Its Complications. 107798. PMID 33309385 DOI: 10.1016/j.jdiacomp.2020.107798  0.223
2011 Iakoubov R, Ahmed A, Lauffer LM, Bazinet RP, Brubaker PL. Essential role for protein kinase Cζ in oleic acid-induced glucagon-like peptide-1 secretion in vivo in the rat. Endocrinology. 152: 1244-52. PMID 21325047 DOI: 10.1210/En.2010-1352  0.22
2017 Hopperton KE, Mohammad D, Trépanier MO, Giuliano V, Bazinet RP. Markers of microglia in post-mortem brain samples from patients with Alzheimer's disease: a systematic review. Molecular Psychiatry. PMID 29230021 DOI: 10.1038/mp.2017.246  0.22
2021 Tran A, He W, Chen JTC, Wellhauser L, Hopperton KE, Bazinet RP, Belsham DD. Palmitate-mediated induction of neuropeptide Y expression occurs through intracellular metabolites and not direct exposure to proinflammatory cytokines. Journal of Neurochemistry. PMID 34482548 DOI: 10.1111/jnc.15504  0.219
2020 Metherel AH, Irfan M, Klingel SL, Mutch DM, Bazinet RP. Higher Increase in Plasma DHA in Females Compared to Males Following EPA Supplementation May Be Influenced by a Polymorphism in ELOVL2: An Exploratory Study. Lipids. PMID 33174255 DOI: 10.1002/lipd.12291  0.218
2023 Lai KZH, Semnani-Azad Z, Boucher BA, Retnakaran R, Harris SB, Malik V, Bazinet RP, Hanley AJ. Association of serum very long-chain saturated fatty acids with changes in insulin sensitivity and beta-cell function: the PROspective Metabolism and Islet cell Evaluation (PROMISE) cohort. Diabetes. PMID 37586083 DOI: 10.2337/db22-1050  0.217
2020 Pal A, Al-Shaer AE, Guesdon W, Torres MJ, Armstrong M, Quinn K, Davis T, Reisdorph N, Neufer PD, Spangenburg EE, Carroll I, Bazinet RP, Halade GV, Clària J, Shaikh SR. Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32579292 DOI: 10.1096/Fj.202000830R  0.216
2004 Bazinet RP, Douglas H, McMillan EG, Wilkie BN, Cunnane SC. Dietary 18:3omega3 influences immune function and the tissue fatty acid response to antigens and adjuvant. Immunology Letters. 95: 85-90. PMID 15325802 DOI: 10.1016/J.Imlet.2004.06.007  0.215
2023 Boachie N, Gaudette E, Bazinet RP, Lin L, Tyndale RF, Mansouri E, Huestis MA, Tong J, Le Foll B, Kish SJ, George TP, Boileau I. Circulating Endocannabinoids and N-Acylethanolamines in Individuals with Cannabis Use Disorder-Preliminary Findings. Brain Sciences. 13. PMID 37891745 DOI: 10.3390/brainsci13101375  0.213
2021 Osmond ATY, Arts MT, Hall JR, Rise ML, Bazinet RP, Armenta RE, Colombo SM. sp. (T18) Oil as a Fish Oil Replacement in Diets for Juvenile Rainbow Trout (): Effects on Growth Performance, Tissue Fatty Acid Content, and Lipid-Related Transcript Expression. Animals : An Open Access Journal From Mdpi. 11. PMID 33924273 DOI: 10.3390/ani11041185  0.212
2003 Bazinet RP, Douglas H, McMillan EG, Wilkie BN, Cunnane SC. Intramuscular injection of antigens and adjuvant preferentially decreases 18:2n-6 and 18:3n-3 in pig neck muscle. Lipids. 38: 1221-6. PMID 14870924 DOI: 10.1007/S11745-003-1182-X  0.211
2023 Cisbani G, Chouinard-Watkins R, Smith ME, Malekanian A, Valenzuela R, Metherel AH, Bazinet RP. Dietary triacetin, but not medium chain triacylglycerides, blunts weight gain in diet-induced rat model of obesity. Lipids. PMID 37997471 DOI: 10.1002/lipd.12381  0.206
2019 YASHPAL S, LIESE AD, WAGENKNECHT LE, HAFFNER SM, JOHNSTON LW, BOUCHER B, BAZINET RP, REWERS M, ROTTER JI, WATKINS SM, HANLEY A. 1576-P: Metabolomic Profiling of the Dietary Approaches to Stop Hypertension (DASH) Diet: Novel Insights for the Nutritional Epidemiology of Type 2 Diabetes Mellitus (T2DM) Diabetes. 68: 1576-P. DOI: 10.2337/Db19-1576-P  0.205
2021 Perlman K, Chouinard-Watkins R, Tanti A, Cisbani G, Orri M, Turecki G, Bazinet RP, Mechawar N. Fatty acid dysregulation in the anterior cingulate cortex of depressed suicides with a history of child abuse. Translational Psychiatry. 11: 535. PMID 34663786 DOI: 10.1038/s41398-021-01657-4  0.201
2007 Rao JS, Ertley RN, Rapoport SI, Bazinet RP, Lee HJ. Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A2 and its transcription factor, activator protein-2. Journal of Neurochemistry. 102: 1918-27. PMID 17550430 DOI: 10.1111/J.1471-4159.2007.04648.X  0.199
2023 Yehia NA, Isai L, Semnani-Azad Z, Lai KZH, Retnakaran R, Harris SB, Beaudry JL, Bazinet RP, Hanley AJ. Association of circulating branched chain fatty acids with insulin sensitivity and beta cell function in the PROMISE cohort. Lipids. PMID 37165723 DOI: 10.1002/lipd.12373  0.197
2015 Bazinet R. Book review Pharmanutrition. 3: 65-66. DOI: 10.1016/J.Phanu.2014.11.001  0.196
2017 Lewis EJH, Perkins BA, Lovblom LE, Bazinet RP, Wolever TMS, Bril V. Effect of omega-3 supplementation on neuropathy in type 1 diabetes: A 12-month pilot trial. Neurology. PMID 28515269 DOI: 10.1212/WNL.0000000000004033  0.196
2003 Cunnane SC, Ryan MA, Nadeau CR, Bazinet RP, Musa-Veloso K, McCloy U. Why is carbon from some polyunsaturates extensively recycled into lipid synthesis? Lipids. 38: 477-84. PMID 12848297 DOI: 10.1007/s11745-003-1087-8  0.192
2019 Metherel AH, Irfan M, Klingel SL, Mutch DM, Bazinet RP. Compound-specific isotope analysis reveals no retroconversion of DHA to EPA but substantial conversion of EPA to DHA following supplementation: a randomized control trial. The American Journal of Clinical Nutrition. PMID 31204771 DOI: 10.1093/ajcn/nqz097  0.179
2015 Parrott MD, Winocur G, Bazinet RP, Ma DW, Greenwood CE. Whole-food diet worsened cognitive dysfunction in an Alzheimer's disease mouse model. Neurobiology of Aging. 36: 90-9. PMID 25212462 DOI: 10.1016/J.Neurobiolaging.2014.08.013  0.175
2017 Santaren ID, Watkins SM, Liese AD, Wagenknecht LE, Rewers MJ, Haffner SM, Lorenzo C, Festa A, Bazinet RP, Hanley AJ. Individual Serum Saturated Fatty Acids and Markers of Chronic Subclinical Inflammation: The Insulin Resistance Atherosclerosis Study (IRAS). Journal of Lipid Research. PMID 28928169 DOI: 10.1194/Jlr.P076836  0.171
2017 Shi SY, Schroer SA, Luk CT, Kim MJ, Dodington DW, Lin L, Sivasubramaniyam T, Cai EP, Lu SY, Wagner KU, Bazinet RP, Woo M. Janus kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. The Journal of Biological Chemistry. PMID 28100771 DOI: 10.1074/Jbc.M116.752519  0.169
2014 Nishi S, Kendall CW, Gascoyne AM, Bazinet RP, Bashyam B, Lapsley KG, Augustin LS, Sievenpiper JL, Jenkins DJ. Effect of almond consumption on the serum fatty acid profile: a dose-response study. The British Journal of Nutrition. 112: 1137-46. PMID 25138064 DOI: 10.1017/S0007114514001640  0.168
2015 Trépanier MO, Kwong KM, Domenichiello AF, Chen CT, Bazinet RP, Burnham WM. Intravenous infusion of docosahexaenoic acid increases serum concentrations in a dose-dependent manner and increases seizure latency in the maximal PTZ model. Epilepsy & Behavior : E&B. 50: 71-76. PMID 26141815 DOI: 10.1016/j.yebeh.2015.05.034  0.167
2022 He W, Tran A, Chen CT, Loganthan N, Bazinet RP, Belsham DD. Oleate restores altered autophagic flux to rescue palmitate lipotoxicity in hypothalamic neurons. Molecular and Cellular Endocrinology. 111753. PMID 35981630 DOI: 10.1016/j.mce.2022.111753  0.166
2015 Pillon NJ, Azizi PM, Li YE, Liu J, Wang C, Chan KL, Hopperton KE, Bazinet RP, Heit B, Bilan PJ, Lee WL, Klip A. Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promotes monocyte adhesion and impairs insulin transcytosis. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00611.2014. PMID 25944880 DOI: 10.1152/Ajpendo.00611.2014  0.165
2012 Shi SY, Martin RG, Duncan RE, Choi D, Lu SY, Schroer SA, Cai EP, Luk CT, Hopperton KE, Domenichiello AF, Tang C, Naples M, Dekker MJ, Giacca A, Adeli K, ... ... Bazinet RP, et al. Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. The Journal of Biological Chemistry. 287: 10277-88. PMID 22275361 DOI: 10.1074/Jbc.M111.317453  0.165
2021 Smith ME, Cisbani G, Lacombe RJS, Bazinet RP. A Scoping Review of Clinical Studies in Infants Fed Formulas Containing Palm Oil or Palm Olein and Sn-2 Palmitate. The Journal of Nutrition. 151: 2997-3035. PMID 34510181 DOI: 10.1093/jn/nxab246  0.165
2007 Bhattacharjee AK, Meister LM, Chang L, Bazinet RP, White L, Rapoport SI. In vivo imaging of disturbed pre- and post-synaptic dopaminergic signaling via arachidonic acid in a rat model of Parkinson's disease. Neuroimage. 37: 1112-21. PMID 17681816 DOI: 10.1016/J.Neuroimage.2007.06.012  0.164
2019 Klingel SL, Metherel AH, Irfan M, Rajna A, Chabowski A, Bazinet RP, Mutch DM. EPA and DHA have divergent effects on serum triglycerides and lipogenesis, but similar effects on lipoprotein lipase activity: a randomized controlled trial. The American Journal of Clinical Nutrition. PMID 31535138 DOI: 10.1093/ajcn/nqz234  0.163
2009 Crawford MA, Bazinet RP, Sinclair AJ. Fat intake and CNS functioning: ageing and disease. Annals of Nutrition & Metabolism. 55: 202-28. PMID 19752543 DOI: 10.1159/000229003  0.163
2017 Sivasubramaniyam T, Schroer SA, Li A, Luk CT, Shi SY, Besla R, Dodington DW, Metherel AH, Kitson AP, Brunt JJ, Lopes J, Wagner KU, Bazinet RP, Bendeck MP, Robbins CS, et al. Hepatic JAK2 protects against atherosclerosis through circulating IGF-1. Jci Insight. 2. PMID 28724798 DOI: 10.1172/Jci.Insight.93735  0.162
2005 Maoz D, Lee HJ, Deutsch J, Rapoport SI, Bazinet RP. Immediate no-flow ischemia decreases rat heart nonesterified fatty acid and increases acyl-CoA species concentrations. Lipids. 40: 1149-54. PMID 16459927 DOI: 10.1007/S11745-005-1479-9  0.161
2015 Kubant R, Poon AN, Sánchez-Hernández D, Domenichiello AF, Huot PS, Pannia E, Cho CE, Hunschede S, Bazinet RP, Anderson GH. A comparison of effects of lard and hydrogenated vegetable shortening on the development of high-fat diet-induced obesity in rats. Nutrition & Diabetes. 5: e188. PMID 26657014 DOI: 10.1038/nutd.2015.40  0.158
2021 Racey M, MacFarlane AJ, Carlson S, Stark KD, Plourde M, Field CJ, Yates AA, Wells GA, Grantham A, Bazinet RP, Ma DWL. Dietary Reference Intakes Based on Chronic Disease Endpoints: Outcomes from a case study workshop for omega 3's EPA and DHA. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. PMID 33583256 DOI: 10.1139/apnm-2020-0994  0.153
2017 Desai HR, Sivasubramaniyam T, Revelo XS, Schroer SA, Luk CT, Rikkala PR, Metherel AH, Dodington DW, Park YJ, Kim MJ, Rapps JA, Besla R, Robbins CS, Wagner KU, Bazinet RP, et al. Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation. Scientific Reports. 7: 7653. PMID 28794431 DOI: 10.1038/S41598-017-07923-0  0.147
2015 Sánchez-Hernández D, Poon AN, Kubant R, Kim H, Huot PS, Cho CE, Pannia E, Reza-López SA, Pausova Z, Bazinet RP, Anderson GH. High vitamin A intake during pregnancy modifies dopaminergic reward system and decreases preference for sucrose in Wistar rat offspring. The Journal of Nutritional Biochemistry. PMID 26456562 DOI: 10.1016/J.Jnutbio.2015.08.020  0.142
2021 Sivasubramaniyam T, Yang J, Pollock E, Chon J, Schroer SA, Li YZ, Metherel AH, Dodington DW, Bazinet RP, Woo M. Hepatic Igf1-deficiency protects against atherosclerosis in female mice. Endocrinology. PMID 33647942 DOI: 10.1210/endocr/bqab040  0.139
2020 Lacombe RJS, Bazinet RP. Natural abundance carbon isotope ratio analysis and its application in the study of diet and metabolism. Nutrition Reviews. PMID 33141222 DOI: 10.1093/nutrit/nuaa109  0.135
2015 Cho CE, Pannia E, Huot PS, Sánchez-Hernández D, Kubant R, Dodington DW, Ward WE, Bazinet RP, Anderson GH. Methyl vitamins contribute to obesogenic effects of a high multivitamin gestational diet and epigenetic alterations in hypothalamic feeding pathways in Wistar rat offspring. Molecular Nutrition & Food Research. 59: 476-89. PMID 25488374 DOI: 10.1002/mnfr.201400663  0.133
2014 Ha V, Sievenpiper JL, de Souza RJ, Jayalath VH, Mirrahimi A, Agarwal A, Chiavaroli L, Mejia SB, Sacks FM, Di Buono M, Bernstein AM, Leiter LA, Kris-Etherton PM, Vuksan V, Bazinet RP, et al. Effect of dietary pulse intake on established therapeutic lipid targets for cardiovascular risk reduction: a systematic review and meta-analysis of randomized controlled trials. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 186: E252-62. PMID 24710915 DOI: 10.1503/Cmaj.131727  0.129
2007 Rao JS, Bazinet RP, Rapoport SI, Lee HJ. Chronic administration of carbamazepine down-regulates AP-2 DNA-binding activity and AP-2alpha protein expression in rat frontal cortex. Biological Psychiatry. 61: 154-61. PMID 16806101 DOI: 10.1016/J.Biopsych.2006.03.029  0.125
2014 Francis BM, Yang J, Song BJ, Gupta S, Maj M, Bazinet RP, Robinson B, Mount HT. Reduced levels of mitochondrial complex I subunit NDUFB8 and linked complex I + III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 39: 347-55. PMID 24217272 DOI: 10.3233/JAD-131499  0.122
2024 Nisha Aji K, Cisbani G, Weidenauer A, Koppel A, Hafizi S, Da Silva T, Kiang M, Rusjan PM, Bazinet RP, Mizrahi R. Neurofilament light-chain (NfL) and 18 kDa translocator protein in early psychosis and its putative high-risk. Brain, Behavior, & Immunity - Health. 37: 100742. PMID 38495956 DOI: 10.1016/j.bbih.2024.100742  0.12
2024 Smith ME, Chen CT, Gohel CA, Cisbani G, Chen DK, Rezaei K, McCutcheon A, Bazinet RP. Upregulated hepatic lipogenesis from dietary sugars in response to low palmitate feeding supplies brain palmitate. Nature Communications. 15: 490. PMID 38233416 DOI: 10.1038/s41467-023-44388-4  0.12
2021 Nishi SK, Viguiliouk E, Blanco Mejia S, Kendall CWC, Bazinet RP, Hanley AJ, Comelli EM, Salas Salvadó J, Jenkins DJA, Sievenpiper JL. Are fatty nuts a weighty concern? A systematic review and meta-analysis and dose-response meta-regression of prospective cohorts and randomized controlled trials. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. e13330. PMID 34494363 DOI: 10.1111/obr.13330  0.115
2009 Sievenpiper JL, Kendall CW, Esfahani A, Wong JM, Carleton AJ, Jiang HY, Bazinet RP, Vidgen E, Jenkins DJ. Effect of non-oil-seed pulses on glycaemic control: a systematic review and meta-analysis of randomised controlled experimental trials in people with and without diabetes. Diabetologia. 52: 1479-95. PMID 19526214 DOI: 10.1007/s00125-009-1395-7  0.115
2007 Vuksan V, Whitham D, Sievenpiper JL, Jenkins AL, Rogovik AL, Bazinet RP, Vidgen E, Hanna A. Supplementation of conventional therapy with the novel grain Salba (Salvia hispanica L.) improves major and emerging cardiovascular risk factors in type 2 diabetes: results of a randomized controlled trial. Diabetes Care. 30: 2804-10. PMID 17686832 DOI: 10.2337/dc07-1144  0.11
2010 Grigoriadis S, Barrett J, Pittini R, Herer E, Zaltz A, Bazinet RP, Bradley L, Kennedy S, Steiner M, Levitt A. Omega-3 supplements in pregnancy: are we too late to identify the possible benefits? Journal of Obstetrics and Gynaecology Canada : Jogc = Journal D'ObstéTrique Et GynéCologie Du Canada : Jogc. 32: 209-16. PMID 20500964 DOI: 10.1016/S1701-2163(16)34446-2  0.1
2021 Semnani-Azad Z, Blanco Mejia S, Connelly PW, Bazinet RP, Retnakaran R, Jenkins DJA, Harris SB, Hanley AJ. The association of soluble CD163, a novel biomarker of macrophage activation, with type 2 diabetes mellitus and its underlying physiological disorders: A systematic review. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. PMID 33913230 DOI: 10.1111/obr.13257  0.096
2023 Carey CN, Paquette M, Sahye-Pudaruth S, Dadvar A, Dinh D, Khodabandehlou K, Liang F, Mishra E, Sidhu M, Brown R, Tandon S, Wanyan J, Bazinet RP, Hanley AJ, Malik V, et al. The Environmental Sustainability of Plant-Based Dietary Patterns: A Scoping Review. The Journal of Nutrition. PMID 36809853 DOI: 10.1016/j.tjnut.2023.02.001  0.095
2023 Pitino MA, Unger S, Doyen A, Pouliot Y, Kothari A, Sergius-Ronot M, Bazinet RP, Stone D, O'Connor DL. Digestion of human milk processed by high pressure processing and Holder pasteurization using a dynamic in vitro model of the preterm infant. Food Chemistry. 411: 135477. PMID 36701922 DOI: 10.1016/j.foodchem.2023.135477  0.091
2007 Ertley RN, Bazinet RP, Lee HJ, Rapoport SI, Rao JS. Chronic treatment with mood stabilizers increases membrane GRK3 in rat frontal cortex. Biological Psychiatry. 61: 246-9. PMID 16697355 DOI: 10.1016/J.Biopsych.2006.03.022  0.09
2021 Semnani-Azad Z, Connelly PW, Bazinet RP, Retnakaran R, Jenkins DJA, Harris SB, Zinman B, Hanley AJ. Adipose Tissue Insulin Resistance Is Longitudinally Associated With Adipose Tissue Dysfunction, Circulating Lipids, and Dysglycemia: The PROMISE Cohort. Diabetes Care. PMID 34001534 DOI: 10.2337/dc20-1918  0.088
2017 Rao JS, Ertley RN, Lee HJ, Rapoport SI, Bazinet RP. Chronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortex. The Pharmacogenomics Journal. PMID 29053139 DOI: 10.1038/tpj.2017.42  0.078
2020 Cisbani G, Bazinet R. TitBrain, Behavior, Immunity and Diet. Brain, Behavior, and Immunity. PMID 32173453 DOI: 10.1016/j.bbi.2020.03.008  0.077
2019 Seneviratne AK, Xu M, Henao JJA, Fajardo VA, Hao Z, Voisin V, Xu GW, Hurren R, Kim S, MacLean N, Wang X, Gronda M, Jeyaraju D, Jitkova Y, Ketela T, ... ... Bazinet R, et al. The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids. Cell Stem Cell. PMID 30930145 DOI: 10.1016/J.Stem.2019.02.020  0.077
2019 Schwartz A, Hunschede S, Lacombe RJS, Chatterjee D, Sánchez-Hernández D, Kubant R, Bazinet R, Hamilton JK, Anderson GH. Acute decrease in plasma testosterone and appetite after either glucose or protein beverages in adolescent males. Clinical Endocrinology. PMID 31055857 DOI: 10.1111/cen.14005  0.074
2009 Kendall C, Sievenpiper J, Carleton A, Esfahani A, Wong J, Jiang H, Bazinet R, Vidgen E, Jenkins D. Effect of dietary pulses on glycaemic control in people with without diabetes: Meta-analyses metaregression models of experimental randomized trials Canadian Journal of Diabetes. 33: 192. DOI: 10.1016/S1499-2671(09)33031-2  0.067
2015 Viguiliouk E, Stewart SE, Jayalath VH, Ng AP, Mirrahimi A, de Souza RJ, Hanley AJ, Bazinet RP, Blanco Mejia S, Leiter LA, Josse RG, Kendall CW, Jenkins DJ, Sievenpiper JL. Effect of Replacing Animal Protein with Plant Protein on Glycemic Control in Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 7: 9804-24. PMID 26633472 DOI: 10.3390/Nu7125509  0.062
2017 Lewis EJ, Perkins BA, Lovblom LE, Bazinet RP, Wolever TM, Bril V. Using in vivo corneal confocal microscopy to identify diabetic sensorimotor polyneuropathy risk profiles in patients with type 1 diabetes. Bmj Open Diabetes Research & Care. 5: e000251. PMID 28243447 DOI: 10.1136/bmjdrc-2016-000251  0.06
2023 Ayoub-Charette S, McGlynn ND, Lee D, Khan TA, Blanco Mejia S, Chiavaroli L, Kavanagh ME, Seider M, Taibi A, Chen CT, Ahmed A, Asbury R, Erlich M, Chen YT, Malik VS, ... Bazinet RP, et al. Rationale, Design and Participants Baseline Characteristics of a Crossover Randomized Controlled Trial of the Effect of Replacing SSBs with NSBs versus Water on Glucose Tolerance, Gut Microbiome and Cardiometabolic Risk in Overweight or Obese Adult SSB Consumer: Strategies to Oppose SUGARS with Non-Nutritive Sweeteners or Water (STOP Sugars NOW) Trial and Ectopic Fat Sub-Study. Nutrients. 15. PMID 36904237 DOI: 10.3390/nu15051238  0.059
2021 Kalache A, Bazinet RP, Carlson S, Evans WJ, Kim CH, Lanham-New S, Visioli F, Griffiths JC. Science-based policy: targeted nutrition for all ages and the role of bioactives. European Journal of Nutrition. PMID 34427766 DOI: 10.1007/s00394-021-02662-5  0.059
2019 Seneviratne AK, Xu M, Aristizabal Henao JJ, Fajardo VA, Hao Z, Voisin V, Xu GW, Hurren R, Kim S, MacLean N, Wang X, Gronda M, Jeyaraju D, Jitkova Y, Ketela T, ... ... Bazinet RP, et al. The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids. Cell Stem Cell. 24: 1007. PMID 31173706 DOI: 10.1016/J.Stem.2019.04.020  0.059
2017 Johnston LW, Harris SB, Retnakaran R, Giacca A, Liu Z, Bazinet RP, Hanley AJ. Association of NEFA composition with insulin sensitivity and beta cell function in the Prospective Metabolism and Islet Cell Evaluation (PROMISE) cohort. Diabetologia. PMID 29275428 DOI: 10.1007/S00125-017-4534-6  0.053
2016 Hafizi S, Tseng HH, Rao N, Selvanathan T, Kenk M, Bazinet RP, Suridjan I, Wilson AA, Meyer JH, Remington G, Houle S, Rusjan PM, Mizrahi R. Imaging Microglial Activation in Untreated First-Episode Psychosis: A PET Study With [(18)F]FEPPA. The American Journal of Psychiatry. appiajp201616020171. PMID 27609240 DOI: 10.1176/Appi.Ajp.2016.16020171  0.051
2023 Badewy R, Cardoso E, Glogauer M, Sgro M, Connor KL, Lai JY, Bazinet RP, Tenenbaum HC, Azarpazhooh A. Oral health-related quality of life among women early postpartum: a cross-sectional study. Journal of Periodontology. PMID 37326008 DOI: 10.1002/JPER.23-0236  0.05
2021 Nishi SK, Kendall CWC, Bazinet RP, Hanley AJ, Comelli EM, Jenkins DJA, Sievenpiper JL. Almond Bioaccessibility in a Randomized Crossover Trial: Is a Calorie a Calorie? Mayo Clinic Proceedings. PMID 33853731 DOI: 10.1016/j.mayocp.2021.01.026  0.046
2009 Sievenpiper J, Kendall C, Esfahani A, Wong J, Carleton A, Bazinet R, Jenkins D. Abstract: P1411 DIETARY PULSES IMPROVE GLYCEMIC CONTROL: A METAANALYSIS OF RANDOMIZED CONTROLLED EXPERIMENTAL TRIALS Atherosclerosis Supplements. 10: e1461. DOI: 10.1016/S1567-5688(09)71419-9  0.042
2020 Khan TA, Chiavaroli L, Bazinet RP, Sievenpiper JL. Apparent conflicts of interest do not preclude scientific rigor. The American Journal of Clinical Nutrition. 111: 915-916. PMID 32266399 DOI: 10.1093/ajcn/nqaa005  0.041
2010 Bazinet RP. From Richard P. Bazinet—New Editor-in-Chief Prostaglandins, Leukotrienes and Essential Fatty Acids. 83: 119. DOI: 10.1016/j.plefa.2010.08.001  0.01
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