Ken J. Kellar - Publications

Affiliations: 
Georgetown University, Washington, DC 
Area:
nicotine

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Year Citation  Score
2020 Alaiyed S, McCann M, Mahajan G, Rajkowska G, Stockmeier CA, Kellar KJ, Wu JY, Conant K. Venlafaxine stimulates an MMP-9-dependent increase in excitatory/inhibitory balance in a stress model of depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32269106 DOI: 10.1523/Jneurosci.2387-19.2020  0.473
2019 Dezfuli G, Olson TT, Martin LM, Keum Y, Siegars BA, Desai A, Uitz M, Sahibzada N, Gillis RA, Kellar KJ. α4β2 nicotinic acetylcholine receptors intrinsically influence body weight in mice. Neuropharmacology. 107921. PMID 31881170 DOI: 10.1016/J.Neuropharm.2019.107921  0.352
2019 Rezvani AH, Wells C, Slade S, Xiao Y, Kellar KJ, Levin ED. Oral sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, reduces nicotine self-administration in rats. Pharmacology, Biochemistry, and Behavior. PMID 30794849 DOI: 10.1016/J.Pbb.2019.02.007  0.388
2018 Harris AC, Muelken P, Smethells JR, Yershova K, Stepanov I, Olson TT, Kellar KJ, LeSage MG. Effects of nicotine-containing and "nicotine-free" e-cigarette refill liquids on intracranial self-stimulation in rats. Drug and Alcohol Dependence. 185: 1-9. PMID 29413432 DOI: 10.1016/j.drugalcdep.2017.11.032  0.439
2017 DeDominicis KE, Sahibzada N, Olson TT, Xiao Y, Wolfe BB, Kellar KJ, Yasuda RP. The stoichiometry (α4)3(β2)2 of the nicotinic acetylcholine receptor predominates in the rat motor cortex. Molecular Pharmacology. PMID 28698187 DOI: 10.1124/Mol.116.106880  0.424
2017 Rezvani AH, Slade S, Wells C, Yenugonda VM, Liu Y, Brown ML, Xiao Y, Kellar KJ, Levin ED. Differential efficacies of the nicotinic α4β2 desensitizing agents in reducing nicotine self-administration in female rats. Psychopharmacology. PMID 28555315 DOI: 10.1007/S00213-017-4641-6  0.497
2015 Forcelli PA, Turner JR, Lee BG, Olson TT, Xie T, Xiao Y, Blendy JA, Kellar KJ. Anxiolytic- and Antidepressant-like Effects of the Methadone Metabolite 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (EMDP). Neuropharmacology. PMID 26365569 DOI: 10.1016/J.Neuropharm.2015.09.012  0.752
2015 Tuan EW, Horti AG, Olson TT, Gao Y, Stockmeier CA, Al-Muhtasib N, Bowman Dalley C, Lewin AE, Wolfe BB, Sahibzada N, Xiao Y, Kellar KJ. AT-1001 Is a Partial Agonist with High Affinity and Selectivity at Human and Rat α3β4 Nicotinic Cholinergic Receptors. Molecular Pharmacology. 88: 640-9. PMID 26162864 DOI: 10.1124/Mol.115.099978  0.829
2015 Ton HT, Smart AE, Aguilar BL, Olson TT, Kellar KJ, Ahern GP. Menthol Enhances the Desensitization of Human α3β4 Nicotinic Acetylcholine Receptors. Molecular Pharmacology. 88: 256-64. PMID 25964258 DOI: 10.1124/Mol.115.098285  0.519
2015 Levin ED, Rezvani AH, Xiao Y, Yenugonda VM, Brown ML, Kellar KJ. Nicotinic treatments not only for tobacco, but also other addictions Biochemical Pharmacology. 97: 635. DOI: 10.1016/J.Bcp.2015.08.040  0.366
2014 Liu Y, Paige M, Olson TT, Al-Muhtasib N, Xie T, Hou S, White MP, Cordova A, Guo JL, Kellar KJ, Xiao Y, Brown ML. Synthesis and pharmacological characterization of new neuronal nicotinic acetylcholine receptor ligands derived from Sazetidine-A. Bioorganic & Medicinal Chemistry Letters. 24: 2954-6. PMID 24844195 DOI: 10.1016/J.Bmcl.2014.04.036  0.354
2014 Horti AG, Gao Y, Kuwabara H, Wang Y, Abazyan S, Yasuda RP, Tran T, Xiao Y, Sahibzada N, Holt DP, Kellar KJ, Pletnikov MV, Pomper MG, Wong DF, Dannals RF. 18F-ASEM, a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor with PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 672-7. PMID 24556591 DOI: 10.2967/Jnumed.113.132068  0.329
2014 Hussmann GP, DeDominicis KE, Turner JR, Yasuda RP, Klehm J, Forcelli PA, Xiao Y, Richardson JR, Sahibzada N, Wolfe BB, Lindstrom J, Blendy JA, Kellar KJ. Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain. Journal of Neurochemistry. 129: 721-31. PMID 24422997 DOI: 10.1111/Jnc.12653  0.826
2013 Yenugonda VM, Xiao Y, Levin ED, Rezvani AH, Tran T, Al-Muhtasib N, Sahibzada N, Xie T, Wells C, Slade S, Johnson JE, Dakshanamurthy S, Kong HS, Tomita Y, Liu Y, ... ... Kellar KJ, et al. Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands. Journal of Medicinal Chemistry. 56: 8404-21. PMID 24047231 DOI: 10.1021/Jm4008455  0.496
2013 Levin ED, Sexton HG, Gordon K, Gordon CJ, Xiao Y, Kellar KJ, Yenugonda VM, Liu Y, White MP, Paige M, Brown ML, Rezvani AH. Effects of the sazetidine-a family of compounds on the body temperature in wildtype, nicotinic receptor β2-/- and α7-/- mice. European Journal of Pharmacology. 718: 167-72. PMID 24036108 DOI: 10.1016/J.Ejphar.2013.08.037  0.423
2013 Liu Y, Richardson J, Tran T, Al-Muhtasib N, Xie T, Yenugonda VM, Sexton HG, Rezvani AH, Levin ED, Sahibzada N, Kellar KJ, Brown ML, Xiao Y, Paige M. Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats. Journal of Medicinal Chemistry. 56: 3000-11. PMID 23540678 DOI: 10.1021/Jm4000374  0.372
2013 Rezvani AH, Cauley M, Xiao Y, Kellar KJ, Levin ED. Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically-induced impaired attention in rats. Psychopharmacology. 226: 35-43. PMID 23100170 DOI: 10.1007/S00213-012-2895-6  0.469
2012 Hussmann GP, Turner JR, Lomazzo E, Venkatesh R, Cousins V, Xiao Y, Yasuda RP, Wolfe BB, Perry DC, Rezvani AH, Levin ED, Blendy JA, Kellar KJ. Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain. The Journal of Pharmacology and Experimental Therapeutics. 343: 441-50. PMID 22899752 DOI: 10.1124/Jpet.112.198085  0.796
2012 Hussmann GP, Kellar KJ. A new radioligand binding assay to measure the concentration of drugs in rodent brain ex vivo. The Journal of Pharmacology and Experimental Therapeutics. 343: 434-40. PMID 22899751 DOI: 10.1124/jpet.112.198069  0.806
2012 Rezvani AH, Timofeeva O, Sexton HG, DeCuir D, Xiao Y, Gordon CJ, Kellar KJ, Levin ED. Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats. European Journal of Pharmacology. 682: 110-7. PMID 22387853 DOI: 10.1016/J.Ejphar.2012.02.031  0.474
2012 Johnson JE, Slade S, Wells C, Petro A, Sexton H, Rezvani AH, Brown ML, Paige MA, McDowell BE, Xiao Y, Kellar KJ, Levin ED. Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats. Psychopharmacology. 222: 269-76. PMID 22297831 DOI: 10.1007/S00213-012-2642-Z  0.365
2011 Hussmann GP, Yasuda RP, Xiao Y, Wolfe BB, Kellar KJ. Endogenously expressed muscarinic receptors in HEK293 cells augment up-regulation of stably expressed α4β2 nicotinic receptors. The Journal of Biological Chemistry. 286: 39726-37. PMID 21940627 DOI: 10.1074/Jbc.M111.289546  0.851
2011 Lomazzo E, Hussmann GP, Wolfe BB, Yasuda RP, Perry DC, Kellar KJ. Effects of chronic nicotine on heteromeric neuronal nicotinic receptors in rat primary cultured neurons. Journal of Neurochemistry. 119: 153-64. PMID 21806615 DOI: 10.1111/J.1471-4159.2011.07408.X  0.823
2011 Turner JR, Ortinski PI, Sherrard RM, Kellar KJ. Cerebellar nicotinic cholinergic receptors are intrinsic to the cerebellum: implications for diverse functional roles. Cerebellum (London, England). 10: 748-57. PMID 21562921 DOI: 10.1007/S12311-011-0285-Y  0.682
2011 Rezvani AH, Cauley M, Sexton H, Xiao Y, Brown ML, Paige MA, McDowell BE, Kellar KJ, Levin ED. Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague-Dawley rats. Psychopharmacology. 215: 621-30. PMID 21274704 DOI: 10.1007/S00213-010-2161-8  0.42
2011 Xiao Y, Tuan E, Yasuda RP, Sahibzada N, Wolfe BB, Horton L, Tran T, Al-Muhtasib N, Iwueze AF, Dipietro JR, Xie T, Paige M, Brown ML, Kellar KJ. Pharmacological properties of sazetidine A, a selective ligand of α4β2 nicotinic acetylcholine receptors Biochemical Pharmacology. 82: 1029. DOI: 10.1016/J.Bcp.2011.07.019  0.834
2010 Lomazzo E, MacArthur L, Yasuda RP, Wolfe BB, Kellar KJ. Quantitative analysis of the heteromeric neuronal nicotinic receptors in the rat hippocampus. Journal of Neurochemistry. 115: 625-34. PMID 20796176 DOI: 10.1111/J.1471-4159.2010.06967.X  0.852
2010 Saba W, Valette H, Granon S, Xiao Y, Kellar KJ, Dollé F, Bottlaender M. [18F]ZW-104, a new radioligand for imaging alpha2-alpha3-alpha4/beta2 central nicotinic acetylcholine receptors: Evaluation in mutant mice. Synapse (New York, N.Y.). 64: 570-2. PMID 20222155 DOI: 10.1002/Syn.20776  0.382
2010 Levin ED, Rezvani AH, Xiao Y, Slade S, Cauley M, Wells C, Hampton D, Petro A, Rose JE, Brown ML, Paige MA, McDowell BE, Kellar KJ. Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 332: 933-9. PMID 20007754 DOI: 10.1124/Jpet.109.162073  0.469
2009 Valette H, Xiao Y, Peyronneau MA, Damont A, Kozikowski AP, Wei ZL, Kassiou M, Kellar KJ, Dollé F, Bottlaender M. 18F-ZW-104: a new radioligand for imaging neuronal nicotinic acetylcholine receptors--in vitro binding properties and PET studies in baboons. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1349-55. PMID 19652217 DOI: 10.2967/jnumed.108.061374  0.324
2009 Xiao Y, Abdrakhmanova GR, Baydyuk M, Hernandez S, Kellar KJ. Rat neuronal nicotinic acetylcholine receptors containing alpha7 subunit: pharmacological properties of ligand binding and function. Acta Pharmacologica Sinica. 30: 842-50. PMID 19448648 DOI: 10.1038/Aps.2009.69  0.753
2008 Cucchiaro G, Xiao Y, Gonzalez-Sulser A, Kellar KJ. Analgesic effects of Sazetidine-A, a new nicotinic cholinergic drug. Anesthesiology. 109: 512-9. PMID 18719450 DOI: 10.1097/Aln.0B013E3181834490  0.403
2008 Chen J, Higby R, Tian D, Tan D, Johnson MD, Xiao Y, Kellar KJ, Feng S, Shields PG. Toxicological analysis of low-nicotine and nicotine-free cigarettes. Toxicology. 249: 194-203. PMID 18599178 DOI: 10.1016/J.Tox.2008.05.009  0.364
2008 Cox BC, Marritt AM, Perry DC, Kellar KJ. Transport of multiple nicotinic acetylcholine receptors in the rat optic nerve: high densities of receptors containing alpha6 and beta3 subunits. Journal of Neurochemistry. 105: 1924-38. PMID 18266937 DOI: 10.1111/J.1471-4159.2008.05282.X  0.768
2008 Moaddel R, Oliveira RV, Kimura T, Hyppolite P, Juhaszova M, Xiao Y, Kellar KJ, Bernier M, Wainer IW. Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type. Analytical Chemistry. 80: 48-54. PMID 18062706 DOI: 10.1021/Ac701943B  0.34
2008 Mao D, Perry DC, Yasuda RP, Wolfe BB, Kellar KJ. The alpha4beta2alpha5 nicotinic cholinergic receptor in rat brain is resistant to up-regulation by nicotine in vivo. Journal of Neurochemistry. 104: 446-56. PMID 17961152 DOI: 10.1111/j.1471-4159.2007.05011.x  0.742
2007 Kozikowski AP, Chellappan SK, Xiao Y, Bajjuri KM, Yuan H, Kellar KJ, Petukhov PA. Chemical medicine: novel 10-substituted cytisine derivatives with increased selectivity for alpha4beta2 nicotinic acetylcholine receptors. Chemmedchem. 2: 1157-61. PMID 17530728 DOI: 10.1002/Cmdc.200700073  0.484
2007 Perry DC, Mao D, Gold AB, McIntosh JM, Pezzullo JC, Kellar KJ. Chronic nicotine differentially regulates alpha6- and beta3-containing nicotinic cholinergic receptors in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 322: 306-15. PMID 17446303 DOI: 10.1124/jpet.107.121228  0.716
2007 Kozikowski AP, Chellappan SK, Henderson D, Fulton R, Giboureau N, Xiao Y, Wei ZL, Guilloteau D, Emond P, Dolle F, Kellar KJ, Kassiou M. Acetylenic pyridines for use in PET imaging of nicotinic receptors. Chemmedchem. 2: 54-7. PMID 17096450 DOI: 10.1002/Cmdc.200600220  0.377
2006 Ortinski PI, Turner JR, Barberis A, Motamedi G, Yasuda RP, Wolfe BB, Kellar KJ, Vicini S. Deletion of the GABA(A) receptor alpha1 subunit increases tonic GABA(A) receptor current: a role for GABA uptake transporters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9323-31. PMID 16957088 DOI: 10.1523/Jneurosci.2610-06.2006  0.55
2006 Mao D, Yasuda RP, Fan H, Wolfe BB, Kellar KJ. Heterogeneity of nicotinic cholinergic receptors in rat superior cervical and nodose Ganglia. Molecular Pharmacology. 70: 1693-9. PMID 16882879 DOI: 10.1124/mol.106.027458  0.707
2006 Xiao Y, Fan H, Musachio JL, Wei ZL, Chellappan SK, Kozikowski AP, Kellar KJ. Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them. Molecular Pharmacology. 70: 1454-60. PMID 16857741 DOI: 10.1124/Mol.106.027318  0.547
2006 Chellappan SK, Xiao Y, Tueckmantel W, Kellar KJ, Kozikowski AP. Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity. Journal of Medicinal Chemistry. 49: 2673-6. PMID 16640326 DOI: 10.1021/Jm051196M  0.353
2006 Ohtani M, Oka T, Badyuk M, Xiao Y, Kellar KJ, Daly JW. Mouse beta-TC6 insulinoma cells: high expression of functional alpha3beta4 nicotinic receptors mediating membrane potential, intracellular calcium, and insulin release. Molecular Pharmacology. 69: 899-907. PMID 16332988 DOI: 10.1124/Mol.105.014902  0.486
2005 Turner JR, Kellar KJ. Nicotinic cholinergic receptors in the rat cerebellum: multiple heteromeric subtypes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9258-65. PMID 16207885 DOI: 10.1523/Jneurosci.2112-05.2005  0.719
2005 Marritt AM, Cox BC, Yasuda RP, McIntosh JM, Xiao Y, Wolfe BB, Kellar KJ. Nicotinic cholinergic receptors in the rat retina: simple and mixed heteromeric subtypes. Molecular Pharmacology. 68: 1656-68. PMID 16129735 DOI: 10.1124/Mol.105.012369  0.788
2005 Wei ZL, Xiao Y, Yuan H, Baydyuk M, Petukhov PA, Musachio JL, Kellar KJ, Kozikowski AP. Novel pyridyl ring C5 substituted analogues of epibatidine and 3-(1-methyl-2(S)-pyrrolidinylmethoxy)pyridine (A-84543) as highly selective agents for neuronal nicotinic acetylcholine receptors containing beta2 subunits. Journal of Medicinal Chemistry. 48: 1721-4. PMID 15771418 DOI: 10.1021/Jm0492406  0.466
2004 Hernandez SC, Vicini S, Xiao Y, Dávila-García MI, Yasuda RP, Wolfe BB, Kellar KJ. The nicotinic receptor in the rat pineal gland is an alpha3beta4 subtype. Molecular Pharmacology. 66: 978-87. PMID 15247319 DOI: 10.1124/Mol.104.002345  0.81
2004 Wei ZL, Xiao Y, Kellar KJ, Kozikowski AP. Synthesis and pharmacological characterization of bivalent ligands of epibatidine at neuronal nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 14: 1855-8. PMID 15050615 DOI: 10.1016/J.Bmcl.2003.10.071  0.465
2004 Xiao Y, Baydyuk M, Wang HP, Davis HE, Kellar KJ. Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells. Bioorganic & Medicinal Chemistry Letters. 14: 1845-8. PMID 15050613 DOI: 10.1016/J.Bmcl.2003.09.105  0.536
2004 Xiao Y, Kellar KJ. The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells. The Journal of Pharmacology and Experimental Therapeutics. 310: 98-107. PMID 15016836 DOI: 10.1124/Jpet.104.066787  0.588
2003 Wei ZL, Xiao Y, George C, Kellar KJ, Kozikowski AP. Functionalization of the alicyclic skeleton of epibatidine: synthesis and nicotinic acetylcholine receptor binding affinities of epibatidine analogues. Organic & Biomolecular Chemistry. 1: 3878-81. PMID 14664377 DOI: 10.1039/B308906A  0.497
2003 Jozwiak K, Hernandez SC, Kellar KJ, Wainer IW. Enantioselective interactions of dextromethorphan and levomethorphan with the alpha 3 beta 4-nicotinic acetylcholine receptor: comparison of chromatographic and functional data. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 797: 373-9. PMID 14630163 DOI: 10.1016/S1570-0232(03)00608-1  0.747
2003 Avila AM, Dávila-García MI, Ascarrunz VS, Xiao Y, Kellar KJ. Differential regulation of nicotinic acetylcholine receptors in PC12 cells by nicotine and nerve growth factor. Molecular Pharmacology. 64: 974-86. PMID 14500754 DOI: 10.1124/Mol.64.4.974  0.543
2003 Dávila-García MI, Musachio JL, Kellar KJ. Chronic nicotine administration does not increase nicotinic receptors labeled by [125I]epibatidine in adrenal gland, superior cervical ganglia, pineal or retina. Journal of Neurochemistry. 85: 1237-46. PMID 12753083 DOI: 10.1046/j.1471-4159.2003.01774.x  0.595
2003 Fitch RW, Xiao Y, Kellar KJ, Daly JW. Membrane potential fluorescence: a rapid and highly sensitive assay for nicotinic receptor channel function. Proceedings of the National Academy of Sciences of the United States of America. 100: 4909-14. PMID 12657731 DOI: 10.1073/Pnas.0630641100  0.429
2003 Wei ZL, Petukhov PA, Xiao Y, Tückmantel W, George C, Kellar KJ, Kozikowski AP. Synthesis, nicotinic acetylcholine receptor binding affinities, and molecular modeling of constrained epibatidine analogues. Journal of Medicinal Chemistry. 46: 921-4. PMID 12620069 DOI: 10.1021/Jm025613W  0.35
2002 Perry DC, Xiao Y, Nguyen HN, Musachio JL, Dávila-García MI, Kellar KJ. Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography. Journal of Neurochemistry. 82: 468-81. PMID 12153472 DOI: 10.1046/J.1471-4159.2002.00951.X  0.506
2002 Ferreira M, Sahibzada N, Shi M, Panico W, Niedringhaus M, Wasserman A, Kellar KJ, Verbalis J, Gillis RA. CNS site of action and brainstem circuitry responsible for the intravenous effects of nicotine on gastric tone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2764-79. PMID 11923442 DOI: 10.1523/Jneurosci.22-07-02764.2002  0.441
2001 Fan H, Scheffel UA, Rauseo P, Xiao Y, Dogan AS, Yokoi F, Hilton J, Kellar KJ, Wong DF, Musachio JL. [125/123I] 5-Iodo-3-pyridyl ethers. syntheses and binding to neuronal nicotinic acetylcholine receptors. Nuclear Medicine and Biology. 28: 911-21. PMID 11711310 DOI: 10.1016/S0969-8051(01)00258-X  0.472
2001 Yeh J, Ferreira M, Ebert S, Yasuda RP, Kellar KJ, Wolfe BB. Axotomy and nerve growth factor regulate levels of neuronal nicotinic acetylcholine receptor alpha3 subunit protein in the rat superior cervical ganglion. Journal of Neurochemistry. 79: 258-65. PMID 11677253 DOI: 10.1046/J.1471-4159.2001.00545.X  0.381
2001 Xiao Y, Smith RD, Caruso FS, Kellar KJ. Blockade of rat alpha3beta4 nicotinic receptor function by methadone, its metabolites, and structural analogs. The Journal of Pharmacology and Experimental Therapeutics. 299: 366-71. PMID 11561100  0.538
2001 Meyer EL, Xiao Y, Kellar KJ. Agonist regulation of rat alpha 3 beta 4 nicotinic acetylcholine receptors stably expressed in human embryonic kidney 293 cells. Molecular Pharmacology. 60: 568-76. PMID 11502889  0.592
2001 Yeh JJ, Yasuda RP, Dávila-García MI, Xiao Y, Ebert S, Gupta T, Kellar KJ, Wolfe BB. Neuronal nicotinic acetylcholine receptor alpha3 subunit protein in rat brain and sympathetic ganglion measured using a subunit-specific antibody: regional and ontogenic expression. Journal of Neurochemistry. 77: 336-46. PMID 11279289 DOI: 10.1046/J.1471-4159.2001.T01-1-00259.X  0.433
2001 Ferreira M, Ebert SN, Perry DC, Yasuda RP, Baker CM, Dávila-García MI, Kellar KJ, Gillis RA. Evidence of a functional alpha7-neuronal nicotinic receptor subtype located on motoneurons of the dorsal motor nucleus of the vagus. The Journal of Pharmacology and Experimental Therapeutics. 296: 260-9. PMID 11160606  0.398
2000 Ferreira M, Singh A, Dretchen KL, Kellar KJ, Gillis RA. Brainstem nicotinic receptor subtypes that influence intragastric and arterial blood pressures. The Journal of Pharmacology and Experimental Therapeutics. 294: 230-8. PMID 10871317  0.502
2000 Hernandez SC, Bertolino M, Xiao Y, Pringle KE, Caruso FS, Kellar KJ. Dextromethorphan and its metabolite dextrorphan block alpha3beta4 neuronal nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 293: 962-7. PMID 10869398  0.796
1999 Kellar KJ, Dávila-García MI, Xiao Y. Pharmacology of neuronal nicotinic acetylcholine recceptors: effects of acute and chronic nicotine. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 1: S117-20; discussion . PMID 11768167 DOI: 10.1080/14622299050011921  0.587
1999 Lukas RJ, Changeux JP, Le Novère N, Albuquerque EX, Balfour DJ, Berg DK, Bertrand D, Chiappinelli VA, Clarke PB, Collins AC, Dani JA, Grady SR, Kellar KJ, Lindstrom JM, Marks MJ, et al. International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits. Pharmacological Reviews. 51: 397-401. PMID 10353988  0.506
1999 Zhang J, Xiao Y, Abdrakhmanova G, Wang W, Cleemann L, Kellar KJ, Morad M. Activation and Ca2+ permeation of stably transfected alpha3/beta4 neuronal nicotinic acetylcholine receptor. Molecular Pharmacology. 55: 970-81. PMID 10347237 DOI: 10.1124/Mol.55.6.970  0.443
1999 Perry DC, Dávila-García MI, Stockmeier CA, Kellar KJ. Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies. The Journal of Pharmacology and Experimental Therapeutics. 289: 1545-52. PMID 10336551  0.668
1999 Wainer IW, Zhang Y, Xiao Y, Kellar KJ. Liquid chromatographic studies with immobilized neuronal nicotinic acetylcholine receptor stationary phases: effects of receptor subtypes, pH and ionic strength on drug-receptor interactions. Journal of Chromatography. B, Biomedical Sciences and Applications. 724: 65-72. PMID 10202958 DOI: 10.1016/S0378-4347(98)00579-9  0.469
1999 Dávila-García MI, Houghtling RA, Qasba SS, Kellar KJ. Nicotinic receptor binding sites in rat primary neuronal cells in culture: characterization and their regulation by chronic nicotine. Brain Research. Molecular Brain Research. 66: 14-23. PMID 10095073 DOI: 10.1016/S0169-328X(98)00344-1  0.532
1998 Zhang Y, Xiao Y, Kellar KJ, Wainer IW. Immobilized nicotinic receptor stationary phase for on-line liquid chromatographic determination of drug-receptor affinities. Analytical Biochemistry. 264: 22-5. PMID 9784183 DOI: 10.1006/Abio.1998.2828  0.48
1998 Xiao Y, Meyer EL, Thompson JM, Surin A, Wroblewski J, Kellar KJ. Rat alpha3/beta4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: pharmacology of ligand binding and function. Molecular Pharmacology. 54: 322-33. PMID 9687574 DOI: 10.1124/Mol.54.2.322  0.54
1998 Zhang Y, Xiao Y, Kellar KJ, Wainer IW. Chromatography stationary phase based upon immobilized nicotinic receptor for on-line determination of ligands-receptor affinities Journal De Pharmacie De Belgique. 53: 125.  0.433
1997 Flores CM, Dávila-García MI, Ulrich YM, Kellar KJ. Differential regulation of neuronal nicotinic receptor binding sites following chronic nicotine administration. Journal of Neurochemistry. 69: 2216-9. PMID 9349569  0.767
1997 Dávila-García MI, Musachio JL, Perry DC, Xiao Y, Horti A, London ED, Dannals RF, Kellar KJ. [125I]IPH, an epibatidine analog, binds with high affinity to neuronal nicotinic cholinergic receptors. The Journal of Pharmacology and Experimental Therapeutics. 282: 445-51. PMID 9223586  0.538
1997 Bertolino M, Kellar KJ, Vicini S, Gillis RA. Nicotinic receptor mediates spontaneous GABA release in the rat dorsal motor nucleus of the vagus. Neuroscience. 79: 671-81. PMID 9219932 DOI: 10.1016/S0306-4522(97)00026-2  0.459
1996 Davila-Garefa MI, Xiao Y, Meyer EL, Wroblewski JT, Surin A, Kellar KJ. Regulation of non-α4/β2 high affinity nicotinic receptors in IMR-32 cells Faseb Journal. 10: A689.  0.365
1996 Mellon RD, Hemandez MC, Flores LR, Kellar KJ, Baver BM. Immunosuppression by morphine, nicotine, and epibatidine: Autonomic nervous system involvement Faseb Journal. 10: A129.  0.365
1996 Xiao Y, Meyer EL, Houghtling RA, Thompson JM, Kellar KJ. Characterization of the rat nicotinic acetylcholine receptor subtypes stably expressed in mammalian cells Faseb Journal. 10: A688.  0.519
1995 London ED, Scheffel U, Kimes AS, Kellar KJ. In vivo labeling of nicotinic acetylcholine receptors in brain with [3H]epibatidine. European Journal of Pharmacology. 278: R1-2. PMID 7664806 DOI: 10.1016/0014-2999(95)00178-N  0.523
1995 Houghtling RA, Dávila-García MI, Kellar KJ. Characterization of (+/-)(-)[3H]epibatidine binding to nicotinic cholinergic receptors in rat and human brain. Molecular Pharmacology. 48: 280-7. PMID 7651361  0.556
1995 Hilakivi-Clarke LA, Corduban TD, Taira T, Hitri A, Deutsch S, Korpi ER, Goldberg R, Kellar KJ. Alterations in brain monoamines and GABAA receptors in transgenic mice overexpressing TGF alpha. Pharmacology, Biochemistry, and Behavior. 50: 593-600. PMID 7617706 DOI: 10.1016/0091-3057(94)00347-5  0.304
1995 Perry DC, Kellar KJ. [3H]epibatidine labels nicotinic receptors in rat brain: an autoradiographic study. The Journal of Pharmacology and Experimental Therapeutics. 275: 1030-4. PMID 7473129  0.457
1992 Flores CM, Rogers SW, Pabreza LA, Wolfe BB, Kellar KJ. A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment. Molecular Pharmacology. 41: 31-7. PMID 1732720  0.759
1992 Kellar KJ, Hulihan-Giblin BA, Mulroney SE, Lumpkin MD, Flores CM. Stimulation of serotonin1A receptors increases release of prolactin in the rat. Neuropharmacology. 31: 643-7. PMID 1357574 DOI: 10.1016/0028-3908(92)90142-C  0.646
1992 Flores CM, Hulihan-Giblin BA, Hornby PJ, Lumpkin MD, Kellar KJ. Partial characterization of a neurotransmitter pathway regulating the in vivo release of prolactin. Neuroendocrinology. 55: 519-28. PMID 1350068 DOI: 10.1159/000126176  0.674
1992 Grimm LJ, Blendy JA, Kellar KJ, Perry DC. Chronic reserpine administration selectively up-regulates beta 1- and alpha 1b-adrenergic receptors in rat brain: an autoradiographic study. Neuroscience. 47: 77-86. PMID 1315939 DOI: 10.1016/0306-4522(92)90122-I  0.691
1991 Henderson TR, Gray AP, Platz RD, Kellar KJ, Dretchen KL. Inhibition of brain choline acetyltransferase in vivo: (E)-1-methyl-4-(1-naphthylvinyl)-1,2,3,6-tetrahydropyridine hydrochloride (B115), a depot form of a potent inhibitor. Toxicology and Applied Pharmacology. 107: 336-43. PMID 1994515 DOI: 10.1016/0041-008X(91)90213-X  0.331
1991 Pabreza LA, Dhawan S, Kellar KJ. [3H]cytisine binding to nicotinic cholinergic receptors in brain. Molecular Pharmacology. 39: 9-12. PMID 1987453  0.526
1991 Blendy JA, Perry DC, Pabreza LA, Kellar KJ. Electroconvulsive shock increases alpha 1b- but not alpha 1a-adrenoceptor binding sites in rat cerebral cortex. Journal of Neurochemistry. 57: 1548-55. PMID 1681031 DOI: 10.1111/j.1471-4159.1991.tb06350.x  0.623
1990 Wagster MV, Whitehouse PJ, Walker LC, Kellar KJ, Price DL. Laminar organization and age-related loss of cholinergic receptors in temporal neocortex of rhesus monkey. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2879-85. PMID 2398366 DOI: 10.1523/Jneurosci.10-09-02879.1990  0.329
1990 Wahlestedt C, Blendy JA, Kellar KJ, Heilig M, Widerlöv E, Ekman R. Electroconvulsive shocks increase the concentration of neocortical and hippocampal neuropeptide Y (NPY)-like immunoreactivity in the rat. Brain Research. 507: 65-8. PMID 2302581 DOI: 10.1016/0006-8993(90)90523-E  0.553
1990 Hulihan-Giblin BA, Lumpkin MD, Kellar KJ. Effects of chronic administration of nicotine on prolactin release in the rat: inactivation of prolactin response by repeated injections of nicotine. The Journal of Pharmacology and Experimental Therapeutics. 252: 21-5. PMID 2299591  0.51
1990 Hulihan-Giblin BA, Lumpkin MD, Kellar KJ. Acute effects of nicotine on prolactin release in the rat: agonist and antagonist effects of a single injection of nicotine. The Journal of Pharmacology and Experimental Therapeutics. 252: 15-20. PMID 2299587  0.474
1990 Blendy JA, Grimm LJ, Perry DC, West-Johnsrud L, Kellar KJ. Electroconvulsive shock differentially increases binding to alpha-1 adrenergic receptor subtypes in discrete regions of rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2580-6. PMID 1974919  0.638
1989 Kellar KJ, Giblin BA, Lumpkin MD. Regulation of brain nicotinic cholinergic recognition sites and prolactin release by nicotine. Progress in Brain Research. 79: 209-16. PMID 2685897  0.426
1989 Flores CM, Hulihan-Giblin BA, Kellar KJ. Naltrexone blocks nicotine-induced prolactin release. Neuropharmacology. 28: 1287-90. PMID 2594167 DOI: 10.1016/0028-3908(89)90225-6  0.719
1989 Stockmeier CA, Kellar KJ. Serotonin depletion unmasks serotonergic component of [3H]dihydroalprenolol binding in rat brain. Molecular Pharmacology. 36: 903-11. PMID 2557537  0.611
1988 Whitehouse PJ, Martino AM, Marcus KA, Zweig RM, Singer HS, Price DL, Kellar KJ. Reductions in acetylcholine and nicotine binding in several degenerative diseases. Archives of Neurology. 45: 722-4. PMID 3390025 DOI: 10.1001/archneur.1988.00520310028012  0.462
1988 Whitehouse PJ, Martino AM, Wagster MV, Price DL, Mayeux R, Atack JR, Kellar KJ. Reductions in [3H]nicotinic acetylcholine binding in Alzheimer's disease and Parkinson's disease: an autoradiographic study. Neurology. 38: 720-3. PMID 3362368 DOI: 10.1212/Wnl.38.5.720  0.349
1988 Gillis RA, Kellar KJ, Quest JA, Namath IJ, Martino-Barrows A, Hill K, Gatti PJ, Dretchen K. Experimental studies on the neurocardiovascular effects of urapidil. Drugs. 35: 20-33. PMID 2900129 DOI: 10.2165/00003495-198800356-00004  0.324
1988 Blendy JA, Stockmeier CA, Kellar KJ. Electroconvulsive shock and reserpine increase alpha 1-adrenoceptor binding sites but not norepinephrine-stimulated phosphoinositide hydrolysis in rat brain. European Journal of Pharmacology. 156: 267-70. PMID 2853676 DOI: 10.1016/0014-2999(88)90330-5  0.721
1988 Stockmeier CA, Kellar KJ. Electroconvulsive shock decreases beta-adrenoceptors despite serotonin lesions. European Journal of Pharmacology. 153: 135-9. PMID 2850925 DOI: 10.1016/0014-2999(88)90598-5  0.604
1987 Martino-Barrows AM, Kellar KJ. [3H]acetylcholine and [3H](-)nicotine label the same recognition site in rat brain. Molecular Pharmacology. 31: 169-74. PMID 3807893  0.452
1987 Kellar KJ, Whitehouse PJ, Martino-Barrows AM, Marcus K, Price DL. Muscarinic and nicotinic cholinergic binding sites in Alzheimer's disease cerebral cortex. Brain Research. 436: 62-8. PMID 3690354 DOI: 10.1016/0006-8993(87)91556-3  0.419
1987 Kellar KJ. Effects of electroconvulsive shock on noradrenergic and serotonergic receptors in rat brain. Pharmacopsychiatry. 20: 30-4. PMID 3547420 DOI: 10.1055/s-2007-1017070  0.318
1987 Ksir C, Hakan RL, Kellar KJ. Chronic nicotine and locomotor activity: influences of exposure dose and test dose. Psychopharmacology. 92: 25-9. PMID 3110825 DOI: 10.1007/Bf00215474  0.31
1987 Kellar KJ, Stockmeier CA, Martino AM. Regulation of beta adrenergic and serotonin-S2 receptors in brain by electroconvulsive shock and serotonin. Psychopharmacology Series. 3: 99-106. PMID 3029757 DOI: 10.1007/978-3-642-71288-3_12  0.614
1987 Whitehouse PJ, Kellar KJ. Nicotinic and muscarinic cholinergic receptors in Alzheimer's disease and related disorders. Journal of Neural Transmission. Supplementum. 24: 175-82. PMID 2960781  0.315
1987 Stockmeier CA, McLeskey SW, Blendy JA, Armstrong NR, Kellar KJ. Electroconvulsive shock but not antidepressant drugs increases alpha 1-adrenoceptor binding sites in rat brain. European Journal of Pharmacology. 139: 259-66. PMID 2822432 DOI: 10.1016/0014-2999(87)90582-6  0.711
1986 Whitehouse PJ, Martino AM, Antuono PG, Lowenstein PR, Coyle JT, Price DL, Kellar KJ. Nicotinic acetylcholine binding sites in Alzheimer's disease. Brain Research. 371: 146-51. PMID 3708340 DOI: 10.1016/0006-8993(86)90819-X  0.42
1986 Kellar KJ, Stockmeier CA. Effects of electroconvulsive shock and serotonin axon lesions on beta-adrenergic and serotonin-2 receptors in rat brain. Annals of the New York Academy of Sciences. 462: 76-90. PMID 3010791 DOI: 10.1111/J.1749-6632.1986.Tb51242.X  0.598
1986 Stockmeier CA, Kellar KJ. In vivo regulation of the serotonin-2 receptor in rat brain. Life Sciences. 38: 117-27. PMID 2935693 DOI: 10.1016/0024-3205(86)90003-2  0.551
1985 Ksir C, Hakan R, Hall DP, Kellar KJ. Exposure to nicotine enhances the behavioral stimulant effect of nicotine and increases binding of [3H]acetylcholine to nicotinic receptors. Neuropharmacology. 24: 527-31. PMID 4022267 DOI: 10.1016/0028-3908(85)90058-9  0.51
1985 Kellar KJ, Martino AM, Hall DP, Schwartz RD, Taylor RL. High-affinity binding of [3H]acetylcholine to muscarinic cholinergic receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 1577-82. PMID 4009247  0.386
1985 Schwartz RD, Kellar KJ. In vivo regulation of [3H]acetylcholine recognition sites in brain by nicotinic cholinergic drugs. Journal of Neurochemistry. 45: 427-33. PMID 4009168  0.525
1985 Stockmeier CA, Martino AM, Kellar KJ. A strong influence of serotonin axons on beta-adrenergic receptors in rat brain. Science (New York, N.Y.). 230: 323-5. PMID 2996132 DOI: 10.1126/Science.2996132  0.623
1985 Kellar KJ, Stockmeier CA, Gomez JM. Regulation of serotonin neurotransmission by antidepressant drugs and electroconvulsive shock: the fall and rise of serotonin receptors. Acta Pharmacologica Et Toxicologica. 56: 138-45. PMID 2984881 DOI: 10.1111/J.1600-0773.1985.Tb02505.X  0.552
1985 Stockmeier CA, Kellar KJ. Evidence for a strong influence of serotonin (5-HT) neurotransmission on beta-adrenergic receptors in rat brain Federation Proceedings. 44: No. 7118.  0.6
1985 Armstrong NA, Stockmeier CA, Kellar KJ. Neurochemical effects of repeated administration of sertraline Federation Proceedings. 44: No. 2780.  0.486
1984 Schwartz RD, Lehmann J, Kellar KJ. Presynaptic nicotinic cholinergic receptors labeled by [3H]acetylcholine on catecholamine and serotonin axons in brain. Journal of Neurochemistry. 42: 1495-8. PMID 6707650  0.41
1984 Rainbow TC, Schwartz RD, Parsons B, Kellar KJ. Quantitative autoradiography of nicotinic [3H]acetylcholine binding sites in rat brain. Neuroscience Letters. 50: 193-6. PMID 6493626 DOI: 10.1016/0304-3940(84)90485-3  0.43
1984 Kellar KJ, Quest JA, Spera AC, Buller A, Conforti A, Dias Souza J, Gillis RA. Comparative effects of urapidil, prazosin, and clonidine on ligand binding to central nervous system receptors, arterial pressure, and heart rate in experimental animals. The American Journal of Medicine. 77: 87-95. PMID 6091452 DOI: 10.1016/S0002-9343(84)80042-X  0.362
1984 Kellar KJ, Schwartz RD, Martino AM, Hall DP. 3H-ACETYLCHOLINE EIN lNG TO MUSCARINIC AND I ICOTINIC CHOLINE GIC RECEPTORS IN BRAIN Clinical Neuropharmacology. 7: S518. DOI: 10.1097/00002826-198406001-00473  0.383
1984 Schwartz RD, Taylor RL, Kellar KJ. Muscarinic cholinergic receptors labeled by [3H]acetylcholine in rat brain Federation Proceedings. 43: no. 1647.  0.425
1983 Schwartz RD, Kellar KJ. Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo. Science (New York, N.Y.). 220: 214-6. PMID 6828889  0.514
1983 Cascio CS, Kellar KJ. Characterization of [3H]tryptamine binding sites in brain. European Journal of Pharmacology. 95: 31-9. PMID 6667714 DOI: 10.1016/0014-2999(83)90264-9  0.312
1983 Schwartz RD, Kellar KJ. [3H]acetylcholine binding sites in brain. Effect of disulfide bond modification. Molecular Pharmacology. 24: 387-91. PMID 6633505  0.395
1983 Kellar KJ, Bergstrom DA. Electroconvulsive shock: effects on biochemical correlates of neurotransmitter receptors in rat brain. Neuropharmacology. 22: 401-6. PMID 6304557 DOI: 10.1016/0028-3908(83)90189-2  0.441
1982 Schwartz RD, McGee R, Kellar KJ. Nicotinic cholinergic receptors labeled by [3H]acetylcholine in rat brain. Molecular Pharmacology. 22: 56-62. PMID 7121451  0.522
1982 Anderson RJ, Brigham P, Cady WJ, Kellar KJ. Role of alpha-2 adrenergic affinity in the action of a non-sedative antispasticity agent. Acta Neurologica Scandinavica. 66: 248-58. PMID 6291304  0.442
1982 Schwartz RD, Moerschbaecher JM, Thompson DM, Kellar KJ. Effects of chronic phencyclidine on fixed-ratio responding: no relation to neurotransmitter receptor binding in rat cerebral cortex. Pharmacology, Biochemistry, and Behavior. 16: 647-52. PMID 6280207 DOI: 10.1016/0091-3057(82)90431-2  0.369
1981 Kellar KJ, Cascio CS, Butler JA, Kurtzke RN. Differential effects of electroconvulsive shock and antidepressant drugs on serotonin-2 receptors in rat brain. European Journal of Pharmacology. 69: 515-8. PMID 7250184 DOI: 10.1016/0014-2999(81)90460-X  0.322
1981 Kellar KJ, Cascio CS, Bergstrom DA, Butler JA, Iadarola P. Electroconvulsive shock and reserpine: effects on beta-adrenergic receptors in rat brain. Journal of Neurochemistry. 37: 830-6. PMID 6275033 DOI: 10.1111/j.1471-4159.1981.tb04468.x  0.422
1980 Treiser S, Kellar KJ. Lithium: effects on serotonin receptors in rat brain. European Journal of Pharmacology. 64: 183-5. PMID 7398763 DOI: 10.1016/0014-2999(80)90044-8  0.395
1979 Treiser S, Kellar KJ. Lithium effects on adrenergic receptor supersensitivity in rat brain. European Journal of Pharmacology. 58: 85-6. PMID 227699 DOI: 10.1016/0014-2999(79)90343-1  0.382
1979 Bergstrom DA, Kellar KJ. Effect of electroconvulsive shock on monoaminergic receptor binding sites in rat brain. Nature. 278: 464-6. PMID 221821  0.376
1979 Bergstrom DA, Kellar KJ. Adrenergic and serotonergic receptor binding in rat brain after chronic desmethylimipramine treatment. The Journal of Pharmacology and Experimental Therapeutics. 209: 256-61. PMID 220405  0.494
1978 Bergstrom DA, Borts RJ, Kellar KJ. Adrenergic and serotonergic receptor binding in brain after chronic desipramime (DMI) treatment Federation Proceedings. 37: No. 1939.  0.375
Low-probability matches (unlikely to be authored by this person)
2010 Rezvani AH, Slade S, Wells C, Petro A, Lumeng L, Li TK, Xiao Y, Brown ML, Paige MA, McDowell BE, Rose JE, Kellar KJ, Levin ED. Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats. Psychopharmacology. 211: 161-74. PMID 20535453 DOI: 10.1007/S00213-010-1878-8  0.296
2018 Levin ED, Rezvani AH, Wells C, Slade S, Yenugonda VM, Liu Y, Brown ML, Xiao Y, Kellar KJ. α4β2 Nicotinic receptor desensitizing compounds can decrease self-administration of cocaine and methamphetamine in rats. European Journal of Pharmacology. PMID 30529197 DOI: 10.1016/J.Ejphar.2018.12.010  0.29
1990 Mandal AK, Zhong PY, Kellar KJ, Gillis RA. Ventrolateral medulla: an important site of action for the hypotensive effect of drugs that activate serotonin-1A receptors. Journal of Cardiovascular Pharmacology. 15: S49-60. PMID 1702487 DOI: 10.1097/00005344-199000157-00007  0.28
1986 Cascio CS, Kellar KJ. Effects of pargyline, reserpine and neurotoxin lesions on [3H]tryptamine binding sites in rat brain. European Journal of Pharmacology. 120: 101-5. PMID 3948908 DOI: 10.1016/0014-2999(86)90646-1  0.278
1982 Kellar KJ, Cascio CS. [3H]Tryptamine: high affinity binding sites in rat brain. European Journal of Pharmacology. 78: 475-8. PMID 7075681 DOI: 10.1016/0014-2999(82)90492-7  0.276
2013 Gao Y, Kellar KJ, Yasuda RP, Tran T, Xiao Y, Dannals RF, Horti AG. Derivatives of dibenzothiophene for positron emission tomography imaging of α7-nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 56: 7574-89. PMID 24050653 DOI: 10.1021/Jm401184F  0.273
1981 Treiser SL, Cascio CS, O'Donohue TL, Thoa NB, Jacobowitz DM, Kellar KJ. Lithium increases serotonin release and decreases serotonin receptors in the hippocampus. Science (New York, N.Y.). 213: 1529-31. PMID 6269180 DOI: 10.1126/science.6269180  0.268
1989 Atack JR, Wenk GL, Wagster MV, Kellar KJ, Whitehouse PJ, Rapoport SI. Bilateral changes in neocortical [3H]pirenzepine and [3H]oxotremorine-M binding following unilateral lesions of the rat nucleus basalis magnocellularis: an autoradiographic study. Brain Research. 483: 367-72. PMID 2706526 DOI: 10.1016/0006-8993(89)90182-0  0.264
1978 Treiser S, Bergstrom DA, Bortz RJ, Kellar KJ. Monoamine binding sites following chronic lithium administration in rats Federation Proceedings. 37: No. 1940.  0.256
2008 Gao Y, Kuwabara H, Spivak CE, Xiao Y, Kellar K, Ravert HT, Kumar A, Alexander M, Hilton J, Wong DF, Dannals RF, Horti AG. Discovery of (-)-7-methyl-2-exo-[3′-(6-[18F]nuoropyridin- 2-yl)-5′-pyridinyl]-7-azabicyclo[2.2.1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (α4β2-nAChR) with optimal positron emission tomography imaging properties Journal of Medicinal Chemistry. 51: 4751-4764. PMID 18605717 DOI: 10.1021/Jm800323D  0.256
2005 Dennis PA, Van Waes C, Gutkind JS, Kellar KJ, Vinson C, Mukhin AG, Spitz MR, Bailey-Wilson JE, Yeh GC, Anderson LM, Wiest JS. The biology of tobacco and nicotine: bench to bedside. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 764-7. PMID 15824140 DOI: 10.1158/1055-9965.Epi-04-0652  0.255
1996 Meyer EL, Xiao Y, Kellar KJ. Pharmacology of the neuronal nicotinic receptor subtypes α2/β4 and α3/β4 Faseb Journal. 10: A689.  0.252
2012 Newhouse P, Kellar K, Aisen P, White H, Wesnes K, Coderre E, Pfaff A, Wilkins H, Howard D, Levin ED. Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. Neurology. 78: 91-101. PMID 22232050 DOI: 10.1212/WNL.0b013e31823efcbb  0.252
1989 Gillis RA, Hill KJ, Kirby JS, Quest JA, Hamosh P, Norman WP, Kellar KJ. Effect of activation of central nervous system serotonin 1A receptors on cardiorespiratory function. The Journal of Pharmacology and Experimental Therapeutics. 248: 851-7. PMID 2521902  0.245
1989 Mandal AK, Kellar KJ, Friedman E, Pineo SV, Hamosh P, Gillis RA. Importance of central nervous system serotonin-1A receptors for mediating the hypotensive effect of urapidil. The Journal of Pharmacology and Experimental Therapeutics. 251: 563-70. PMID 2530339  0.241
1982 Cascio CS, Kellar KJ. Tetrahydro-beta-carbolines: affinities for tryptamine and serotonergic binding sites. Neuropharmacology. 21: 1219-21. PMID 7177348 DOI: 10.1016/0028-3908(82)90185-X  0.239
1988 Perry DC, Grimm LJ, Kettler KG, Kellar KJ. [3H]tryptamine binding sites are not identical to monoamine oxidase in rat brain. Journal of Neurochemistry. 51: 1535-40. PMID 3139835 DOI: 10.1111/j.1471-4159.1988.tb01122.x  0.239
2016 Dezfuli G, Kellar KJ, Dretchen KL, Tizabi Y, Sahibzada N, Gillis RA. Evidence for the role of β2* nAChR desensitization in regulating body weight in obese mice. Neuropharmacology. PMID 27444741 DOI: 10.1016/J.Neuropharm.2016.07.020  0.217
1994 Mulroney SE, Skudlarek C, Shemer A, Lumpkin MD, Kellar KJ. Tandospirone stimulates prolactin secretion in the rat by an action at serotonin-1A receptors. The Journal of Pharmacology and Experimental Therapeutics. 268: 862-7. PMID 8113999  0.214
2015 Gao Y, Mease RC, Olson TT, Kellar KJ, Dannals RF, Pomper MG, Horti AG. [(125)I]Iodo-ASEM, a specific in vivo radioligand for α7-nAChR. Nuclear Medicine and Biology. 42: 488-93. PMID 25687449 DOI: 10.1016/J.Nucmedbio.2014.12.008  0.211
1991 Mandal AK, Kellar KJ, Gillis RA. The role of serotonin-1A receptor activation and alpha-1 adrenoceptor blockade in the hypotensive effect of 5-methyl-urapidil. The Journal of Pharmacology and Experimental Therapeutics. 257: 861-9. PMID 1674536  0.199
1982 Kellar KJ, Cascio CS. Tryptamine binding sites: potential site of action of tetrahydro-beta-carbolines. Progress in Clinical and Biological Research. 90: 209-12. PMID 7111320  0.19
1994 Travagli RA, Gillis RA, Kellar KJ. S-adenosyl-L-methionine modulates firing rate of dorsal motor nucleus of the vagus neurones in vitro. European Journal of Pharmacology. 264: 385-90. PMID 7698179 DOI: 10.1016/0014-2999(94)00504-4  0.148
1975 Kellar KJ, Sterling GH. Lesions in the ventromedial hypothalamus of rats produced by goldthioglucose Federation Proceedings. 34: No. 371.  0.14
1978 Helke CJ, Kellar KJ, Gillis RA. Effect of arrhythmogenic doses of deslanoside on the uptake of monoamines in brain tissue and in cardiac tissue. European Journal of Pharmacology. 52: 47-55. PMID 31290 DOI: 10.1016/0014-2999(78)90020-1  0.138
1990 Mandal AK, Kellar KJ, Norman WP, Gillis RA. Stimulation of serotonin2 receptors in the ventrolateral medulla of the cat results in nonuniform increases in sympathetic outflow. Circulation Research. 67: 1267-80. PMID 2225358 DOI: 10.1161/01.Res.67.5.1267  0.129
1975 Kellar KJ, Sterling GH, O'Neill JJ. Effect of diabetes on gold thioglucose lesions in rats. Proceedings of the Western Pharmacology Society. 18: 380-3. PMID 1101273  0.109
1999 Mirski DF, Barkin K, Cohen-Mansfield J, Kellar K, Bachman D, Sallee F, Mintzer JE. PLATELET PAROXETINE BINDING TO 5-HT UPTAKE SITES IN ELDERLY PATIENTS WITH ALZHEIMER's DISEASE WITH AGITATION AND AGGRESSION The American Journal of Geriatric Psychiatry. 7: 50-51. DOI: 10.1097/00019442-199911001-00146  0.106
1979 Helke CJ, Kellar KJ, Gillis RA. Effect of in vivo deslanoside on the uptake of serotonin into platelets. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 242: 44-9. PMID 543748  0.072
1978 Helke CJ, Yuhaniak PA, Kellar KJ, Gillis RA. Effect of deslanoside on brain and spinal cord levels of serotonin and 5-hydroxy-indoleacetic acid and tryptophan hydroxylase activity. Biochemical Pharmacology. 27: 2459-61. PMID 728197 DOI: 10.1016/0006-2952(78)90360-X  0.072
1977 Vernikos-Danellis J, Kellar KJ, Kent D, Gonzales C, Berger PA, Barchas JD. Serotonin involvement in pituitary-adrenal function. Annals of the New York Academy of Sciences. 297: 518-26. PMID 279261  0.061
2006 Kellar KJ. Overcoming inhibitions. Proceedings of the National Academy of Sciences of the United States of America. 103: 13263-4. PMID 16938861 DOI: 10.1073/pnas.0606052103  0.055
1978 Gillis RA, Helke CJ, Kellar KJ, Quest JA. Autonomic nervous system actions of cardiac glycosides. Biochemical Pharmacology. 27: 849-56. PMID 350228 DOI: 10.1016/0006-2952(78)90408-2  0.055
1975 Kellar KJ, Langley AE, Marks BH, O'Neill JJ. Ventral medial hypothalamus: involvement in hypoglycemic convulsions. Science (New York, N.Y.). 187: 746-8. PMID 1090001  0.053
1977 Kellar KJ, Brown PA, Madrid J, Bernstein M, Vernikos-Danellis J, Mehler WR. Origins of serotonin innervation of forebrain structures. Experimental Neurology. 56: 52-62. PMID 862695 DOI: 10.1016/0014-4886(77)90138-8  0.051
1973 Kellar KJ, Langley AE, Marks BH, O'Neill JJ. Hypothalamic lesions block hypoglycemic convulsions Pharmacologist. 15: 230.  0.05
1974 Kellar KJ, O'Neill JJ. Neurochemical changes associated with goldthioglucose lesions of the ventral medial hypothalamus Trans.Amer.Soc.Neurochem.. 5: 186.  0.041
1975 Kellar KJ, Elliott GR, Holman RB. Tryptolines: inhibitors of 5 hydroxytryptamine uptake Pharmacologist. 17: No.459.  0.035
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