| Year |
Citation |
Score |
| 2023 |
Marzi SJ, Schilder BM, Nott A, Frigerio CS, Willaime-Morawek S, Bucholc M, Hanger DP, James C, Lewis PA, Lourida I, Noble W, Rodriguez-Algarra F, Sharif JA, Tsalenchuk M, Winchester LM, et al. Artificial intelligence for neurodegenerative experimental models. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37768001 DOI: 10.1002/alz.13479 |
0.536 |
|
| 2023 |
Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp MD, Jimenez-Sanchez M, Perkinton MS, Kassiou M, Golde TE, Hanger DP, Verkhratsky A, Perez-Nievas BG, Noble W. P2XR influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes. Brain, Behavior, and Immunity. 114: 414-429. PMID 37716378 DOI: 10.1016/j.bbi.2023.09.011 |
0.846 |
|
| 2023 |
Noble W, Hanger DP. Trimming away tau in neurodegeneration. Science (New York, N.Y.). 381: 377-378. PMID 37499007 DOI: 10.1126/science.adj0256 |
0.649 |
|
| 2023 |
Matafora V, Gorb A, Yang F, Noble W, Bachi A, Perez-Nievas BG, Jimenez-Sanchez M. Proteomics of the astrocyte secretome reveals changes in their response to soluble oligomeric Aβ. Journal of Neurochemistry. 166: 346-366. PMID 37303123 DOI: 10.1111/jnc.15875 |
0.413 |
|
| 2022 |
Beltran-Lobo P, Reid MJ, Jimenez-Sanchez M, Verkhratsky A, Perez-Nievas BG, Noble W. Astrocyte adaptation in Alzheimer's disease: a focus on astrocytic P2X7R. Essays in Biochemistry. PMID 36449279 DOI: 10.1042/EBC20220079 |
0.44 |
|
| 2022 |
Rupawala H, Shah K, Davies C, Rose J, Colom-Cadena M, Peng X, Granat L, Aljuhani M, Mizuno K, Troakes C, Perez-Nievas BG, Morgan A, So PW, Hortobagyi T, Spires-Jones TL, ... Noble W, et al. Cysteine string protein alpha accumulates with early pre-synaptic dysfunction in Alzheimer's disease. Brain Communications. 4: fcac192. PMID 35928052 DOI: 10.1093/braincomms/fcac192 |
0.366 |
|
| 2022 |
Gomez-Suaga P, Mórotz GM, Markovinovic A, Martín-Guerrero SM, Preza E, Arias N, Mayl K, Aabdien A, Gesheva V, Nishimura A, Annibali A, Lee Y, Mitchell JC, Wray S, Shaw C, ... Noble W, et al. Disruption of ER-mitochondria tethering and signalling in C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia. Aging Cell. e13549. PMID 35026048 DOI: 10.1111/acel.13549 |
0.518 |
|
| 2021 |
Sung K, Yang F, Noble W, Jimenez-Sanchez M. Investigating the non-cell autonomous role of glial chaperones in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058572. PMID 34971177 DOI: 10.1002/alz.058572 |
0.429 |
|
| 2021 |
Pollack SJ, Dakkak D, Guo T, Gómez-Suaga P, Noble W, Hanger DP. Autophagy and lysosomal defects in cells expressing disease-associated tau. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058299. PMID 34971173 DOI: 10.1002/alz.058299 |
0.74 |
|
| 2021 |
Goniotaki D, Tamagnini F, Biasetti L, Rumpf SL, Troakes C, Pollack SJ, Ukwesa S, Sun H, Serpell L, Noble W, Staras K, Hanger DP. HCN channelopathy couples disease-associated tau to synaptic dysfunction. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058346. PMID 34971152 DOI: 10.1002/alz.058346 |
0.64 |
|
| 2021 |
Perez-Nievas BG, Johnson L, Beltran-Lobo P, Hughes MM, Gammallieri L, Tarsitano F, Myszczynska MA, Vazquez-Villasenor I, Jimenez-Sanchez M, Troakes C, Wharton SB, Ferraiuolo L, Noble W. Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity. Journal of Neuroinflammation. 18: 306. PMID 34963475 DOI: 10.1186/s12974-021-02371-0 |
0.416 |
|
| 2021 |
Derkinderen P, Rolli-Derkinderen M, Chapelet G, Neunlist M, Noble W. Tau in the gut, does it really matter? Journal of Neurochemistry. PMID 33569813 DOI: 10.1111/jnc.15320 |
0.376 |
|
| 2020 |
Staurenghi E, Cerrato V, Gamba P, Testa G, Giannelli S, Leoni V, Caccia C, Buffo A, Noble W, Perez-Nievas BG, Leonarduzzi G. Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2. Redox Biology. 39: 101837. PMID 33360775 DOI: 10.1016/j.redox.2020.101837 |
0.397 |
|
| 2020 |
Reid MJ, Beltran-Lobo P, Johnson L, Perez-Nievas BG, Noble W. Astrocytes in Tauopathies. Frontiers in Neurology. 11: 572850. PMID 33071951 DOI: 10.3389/fneur.2020.572850 |
0.429 |
|
| 2020 |
Lau DHW, Paillusson S, Hartopp N, Rupawala H, Mórotz GM, Gomez-Suaga P, Greig J, Troakes C, Noble W, Miller CCJ. Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain. Neurobiology of Disease. 105020. PMID 32682953 DOI: 10.1016/J.Nbd.2020.105020 |
0.467 |
|
| 2020 |
Glennon EB, Lau DH, Gabriele RMC, Taylor MF, Troakes C, Opie-Martin S, Elliott C, Killick R, Hanger DP, Perez-Nievas BG, Noble W. Bridging Integrator-1 protein loss in Alzheimer's disease promotes synaptic tau accumulation and disrupts tau release. Brain Communications. 2. PMID 32500121 DOI: 10.1093/braincomms/fcaa011 |
0.75 |
|
| 2020 |
Prigent A, Chapelet G, De Guilhem de Lataillade A, Oullier T, Durieu E, Bourreille A, Duchalais E, Hardonnière K, Neunlist M, Noble W, Kerdine-Römer S, Derkinderen P, Rolli-Derkinderen M. Tau accumulates in Crohn's disease gut. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32436623 DOI: 10.1096/Fj.202000414R |
0.446 |
|
| 2019 |
Hanger DP, Goniotaki D, Noble W. Synaptic Localisation of Tau. Advances in Experimental Medicine and Biology. 1184: 105-112. PMID 32096032 DOI: 10.1007/978-981-32-9358-8_9 |
0.743 |
|
| 2019 |
Mórotz GM, Glennon EB, Greig J, Lau DHW, Bhembre N, Mattedi F, Muschalik N, Noble W, Vagnoni A, Miller CCJ. Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein. Acta Neuropathologica Communications. 7: 200. PMID 31806024 DOI: 10.1186/S40478-019-0857-5 |
0.409 |
|
| 2019 |
Howard R, Zubko O, Bradley R, Harper E, Pank L, O'Brien J, Fox C, Tabet N, Livingston G, Bentham P, McShane R, Burns A, Ritchie C, Reeves S, Lovestone S, ... ... Noble W, et al. Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial. Jama Neurology. PMID 31738372 DOI: 10.1001/Jamaneurol.2019.3762 |
0.471 |
|
| 2019 |
Noble W, Jimenez-Sanchez M, Perez-Nievas BG, Hanger DP. Considerations for future tau-targeted therapeutics: can they deliver? Expert Opinion On Drug Discovery. 1-3. PMID 31661994 DOI: 10.1080/17460441.2020.1685977 |
0.649 |
|
| 2019 |
Mauricio R, Benn C, Davis J, Dawson G, Dawson LA, Evans A, Fox N, Gallacher J, Hutton M, Isaac J, Jones DNC, Jones L, Lalli G, Libri V, Lovestone S, ... ... Noble W, et al. Tackling gaps in developing life-changing treatments for dementia. Alzheimer's & Dementia (New York, N. Y.). 5: 241-253. PMID 31297438 DOI: 10.1016/J.Trci.2019.05.001 |
0.339 |
|
| 2019 |
Mórotz GM, Glennon EB, Gomez-Suaga P, Lau DHW, Robinson ED, Sedlák É, Vagnoni A, Noble W, Miller CCJ. LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains. Acta Neuropathologica Communications. 7: 73. PMID 31068217 DOI: 10.1186/S40478-019-0715-5 |
0.388 |
|
| 2019 |
Gómez-Suaga P, Pérez-Nievas BG, Glennon EB, Lau DHW, Paillusson S, Mórotz GM, Calì T, Pizzo P, Noble W, Miller CCJ. The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity. Acta Neuropathologica Communications. 7: 35. PMID 30841933 DOI: 10.1186/S40478-019-0688-4 |
0.376 |
|
| 2019 |
Guo T, Dakkak D, Rodriguez-Martin T, Noble W, Hanger DP. A pathogenic tau fragment compromises microtubules, disrupts insulin signaling and induces the unfolded protein response. Acta Neuropathologica Communications. 7: 2. PMID 30606258 DOI: 10.1186/s40478-018-0651-9 |
0.705 |
|
| 2018 |
Lionnet A, Wade MA, Corbillé AG, Prigent A, Paillusson S, Tasselli M, Gonzales J, Durieu E, Rolli-Derkinderen M, Coron E, Duchalais E, Neunlist M, Perkinton MS, Hanger DP, Noble W, et al. Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy. Acta Neuropathologica Communications. 6: 65. PMID 30037345 DOI: 10.1186/S40478-018-0568-3 |
0.732 |
|
| 2018 |
Croft CL, Noble W. Preparation of organotypic brain slice cultures for the study of Alzheimer's disease. F1000research. 7: 592. PMID 29904599 DOI: 10.12688/F1000Research.14500.2 |
0.794 |
|
| 2018 |
Giacomini C, Koo CY, Yankova N, Tavares IA, Wray S, Noble W, Hanger DP, Morris JDH. A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies. Acta Neuropathologica Communications. 6: 37. PMID 29730992 DOI: 10.1186/S40478-018-0539-8 |
0.787 |
|
| 2017 |
Croft CL, Kurbatskaya K, Hanger DP, Noble W. Inhibition of glycogen synthase kinase-3 by BTA-EG4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer's disease. Scientific Reports. 7: 7434. PMID 28785087 DOI: 10.1038/S41598-017-07906-1 |
0.845 |
|
| 2017 |
Guo T, Noble W, Hanger DP. Roles of tau protein in health and disease. Acta Neuropathologica. PMID 28386764 DOI: 10.1007/s00401-017-1707-9 |
0.719 |
|
| 2017 |
Paillusson S, Gomez-Suaga P, Stoica R, Little D, Gissen P, Devine MJ, Noble W, Hanger DP, Miller CC. α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca(2+) homeostasis and mitochondrial ATP production. Acta Neuropathologica. PMID 28337542 DOI: 10.1007/S00401-017-1704-Z |
0.619 |
|
| 2017 |
Croft CL, Wade MA, Kurbatskaya K, Mastrandreas P, Hughes MM, Phillips EC, Pooler AM, Perkinton MS, Hanger DP, Noble W. Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures. Cell Death & Disease. 8: e2671. PMID 28300838 DOI: 10.1038/Cddis.2017.97 |
0.841 |
|
| 2017 |
Kerr F, Sofola-Adesakin O, Ivanov DK, Gatliff J, Gomez Perez-Nievas B, Bertrand HC, Martinez P, Callard R, Snoeren I, Cochemé HM, Adcott J, Khericha M, Castillo-Quan JI, Wells G, Noble W, et al. Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease. Plos Genetics. 13: e1006593. PMID 28253260 DOI: 10.1371/Journal.Pgen.1006593 |
0.499 |
|
| 2017 |
Gomez-Suaga P, Paillusson S, Stoica R, Noble W, Hanger DP, Miller CC. The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy. Current Biology : Cb. PMID 28132811 DOI: 10.1016/J.Cub.2016.12.038 |
0.572 |
|
| 2017 |
Hanger DP, Croft CL, Lau DH, Noble W. ACTIVITY-DEPENDENT TAU RELEASE: IMPLICATIONS FOR TAU PROPAGATION Alzheimer's & Dementia. 13: P888. DOI: 10.1016/J.Jalz.2017.07.288 |
0.819 |
|
| 2017 |
Giacomini C, Noble W, Hanger DP, Morris JD. [P1-223]: FUNCTIONAL ROLES FOR TAOK KINASES IN THE DEVELOPMENT OF TAU PATHOLOGY IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P328-P329. DOI: 10.1016/J.Jalz.2017.06.043 |
0.727 |
|
| 2016 |
Tiwari SS, Mizuno K, Ghosh A, Aziz W, Troakes C, Daoud J, Golash V, Noble W, Hortobágyi T, Giese KP. Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss. Brain : a Journal of Neurology. PMID 27524794 DOI: 10.1093/Brain/Aww205 |
0.533 |
|
| 2016 |
Stoica R, Paillusson S, Gomez-Suaga P, Mitchell JC, Lau DH, Gray EH, Sancho RM, Vizcay-Barrena G, De Vos KJ, Shaw CE, Hanger DP, Noble W, Miller CC. ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations. Embo Reports. PMID 27418313 DOI: 10.15252/Embr.201541726 |
0.6 |
|
| 2016 |
Bondulich MK, Guo T, Meehan C, Manion J, Rodriguez Martin T, Mitchell JC, Hortobagyi T, Yankova N, Stygelbout V, Brion JP, Noble W, Hanger DP. Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate. Brain : a Journal of Neurology. PMID 27297240 DOI: 10.1093/Brain/Aww137 |
0.733 |
|
| 2016 |
Lau DH, Hogseth M, Phillips EC, O'Neill MJ, Pooler AM, Noble W, Hanger DP. Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease. Acta Neuropathologica Communications. 4: 49. PMID 27193083 DOI: 10.1186/S40478-016-0317-4 |
0.777 |
|
| 2016 |
Kurbatskaya K, Phillips EC, Croft CL, Dentoni G, Hughes MM, Wade MA, Al-Sarraj S, Troakes C, O'Neill MJ, Perez-Nievas BG, Hanger DP, Noble W. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain. Acta Neuropathologica Communications. 4: 34. PMID 27036949 DOI: 10.1186/S40478-016-0299-2 |
0.824 |
|
| 2016 |
Hughes MM, Perez-Nievas BG, Troakes C, Perkinton M, Hanger DP, Noble W. Post-Mortem Brain Tissue Characterisation Of Inflammatory And Pathological Hallmarks Of Alzheimer’S Disease During Disease Progression Alzheimers & Dementia. 12: 462. DOI: 10.1016/J.Jalz.2016.06.903 |
0.398 |
|
| 2015 |
Tiwari SS, d'Orange M, Troakes C, Shurovi BN, Engmann O, Noble W, Hortobágyi T, Giese KP. Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease. Molecular Brain. 8: 6. PMID 25631211 DOI: 10.1186/S13041-015-0096-Z |
0.473 |
|
| 2015 |
Croft CL, Hanger DP, Noble W. P3-054: The amyloid-binding agent bta-eg4
reduces pathological tau species in a novel organotypic 3xTg-AD brain slice culture model that recapitulates key in vivo
degenerative phenotypes Alzheimer's & Dementia. 11: P639-P639. DOI: 10.1016/J.Jalz.2015.06.921 |
0.822 |
|
| 2014 |
Phillips EC, Croft CL, Kurbatskaya K, O'Neill MJ, Hutton ML, Hanger DP, Garwood CJ, Noble W. Astrocytes and neuroinflammation in Alzheimer's disease. Biochemical Society Transactions. 42: 1321-5. PMID 25233410 DOI: 10.1042/Bst20140155 |
0.833 |
|
| 2014 |
Hanger DP, Lau DH, Phillips EC, Bondulich MK, Guo T, Woodward BW, Pooler AM, Noble W. Intracellular and extracellular roles for tau in neurodegenerative disease. Journal of Alzheimer's Disease : Jad. 40: S37-45. PMID 24595196 DOI: 10.3233/Jad-132054 |
0.756 |
|
| 2014 |
Pooler AM, Noble W, Hanger DP. A role for tau at the synapse in Alzheimer's disease pathogenesis. Neuropharmacology. 76: 1-8. PMID 24076336 DOI: 10.1016/J.Neuropharm.2013.09.018 |
0.731 |
|
| 2014 |
Atherton J, Kurbatskaya K, Bondulich M, Croft CL, Garwood CJ, Chhabra R, Wray S, Jeromin A, Hanger DP, Noble W. Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease. Aging Cell. 13: 49-59. PMID 23919677 DOI: 10.1111/Acel.12148 |
0.818 |
|
| 2014 |
Killick R, Ribe EM, Al-Shawi R, Malik B, Hooper C, Fernandes C, Dobson R, Nolan PM, Lourdusamy A, Furney S, Lin K, Breen G, Wroe R, To AW, Leroy K, ... ... Noble W, et al. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway. Molecular Psychiatry. 19: 88-98. PMID 23164821 DOI: 10.1038/mp.2012.163 |
0.459 |
|
| 2014 |
Phillips EC, Garwood CJ, Hanger DP, Noble W. P1-116: ASTROCYTE ACTIVATION INFLUENCES THE DEVELOPMENT OF TAUOPATHY Alzheimer's & Dementia. 10: P343-P343. DOI: 10.1016/J.Jalz.2014.05.353 |
0.713 |
|
| 2014 |
Lau DH, Pooler AM, Noble W, Hanger DP. P1-115: IDENTIFICATION OF THE BINDING SITE BETWEEN TAU AND FYN: CONSEQUENCES FOR TAU RELEASE? Alzheimer's & Dementia. 10: P343-P343. DOI: 10.1016/J.Jalz.2014.05.352 |
0.602 |
|
| 2013 |
Noble W, Hanger DP, Miller CC, Lovestone S. The importance of tau phosphorylation for neurodegenerative diseases. Frontiers in Neurology. 4: 83. PMID 23847585 DOI: 10.3389/Fneur.2013.00083 |
0.777 |
|
| 2013 |
Vagnoni A, Glennon EB, Perkinton MS, Gray EH, Noble W, Miller CC. Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production. Human Molecular Genetics. 22: 4646-52. PMID 23825109 DOI: 10.1093/Hmg/Ddt313 |
0.427 |
|
| 2013 |
RodrÃguez-MartÃn T, Cuchillo-Ibáñez I, Noble W, Nyenya F, Anderton BH, Hanger DP. Tau phosphorylation affects its axonal transport and degradation. Neurobiology of Aging. 34: 2146-57. PMID 23601672 DOI: 10.1016/J.Neurobiolaging.2013.03.015 |
0.749 |
|
| 2013 |
Tavares IA, Touma D, Lynham S, Troakes C, Schober M, Causevic M, Garg R, Noble W, Killick R, Bodi I, Hanger DP, Morris JD. Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. The Journal of Biological Chemistry. 288: 15418-29. PMID 23585562 DOI: 10.1074/Jbc.M112.448183 |
0.749 |
|
| 2013 |
Pooler AM, Phillips EC, Lau DH, Noble W, Hanger DP. Physiological release of endogenous tau is stimulated by neuronal activity. Embo Reports. 14: 389-94. PMID 23412472 DOI: 10.1038/Embor.2013.15 |
0.725 |
|
| 2013 |
Pooler A, Phillips E, Lau D, Noble W, Hanger D. O2-01-03: Neuronal activity regulates secretion of endogenous tau Alzheimer's & Dementia. 9: P314-P315. DOI: 10.1016/J.Jalz.2013.04.137 |
0.65 |
|
| 2012 |
Johnson R, Noble W, Tartaglia GG, Buckley NJ. Neurodegeneration as an RNA disorder. Progress in Neurobiology. 99: 293-315. PMID 23063563 DOI: 10.1016/J.Pneurobio.2012.09.006 |
0.344 |
|
| 2012 |
Vagnoni A, Perkinton MS, Gray EH, Francis PT, Noble W, Miller CC. Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production. Human Molecular Genetics. 21: 2845-54. PMID 22434822 DOI: 10.1093/Hmg/Dds109 |
0.407 |
|
| 2012 |
Pooler AM, Usardi A, Evans CJ, Philpott KL, Noble W, Hanger DP. Dynamic association of tau with neuronal membranes is regulated by phosphorylation. Neurobiology of Aging. 33: 431.e27-38. PMID 21388709 DOI: 10.1016/J.Neurobiolaging.2011.01.005 |
0.706 |
|
| 2011 |
Noble W, Pooler AM, Hanger DP. Advances in tau-based drug discovery. Expert Opinion On Drug Discovery. 6: 797-810. PMID 22003359 DOI: 10.1517/17460441.2011.586690 |
0.736 |
|
| 2011 |
Hanger DP, Noble W. Functional implications of glycogen synthase kinase-3-mediated tau phosphorylation. International Journal of Alzheimer's Disease. 2011: 352805. PMID 21776376 DOI: 10.4061/2011/352805 |
0.748 |
|
| 2011 |
Usardi A, Pooler AM, Seereeram A, Reynolds CH, Derkinderen P, Anderton B, Hanger DP, Noble W, Williamson R. Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau. The Febs Journal. 278: 2927-37. PMID 21692989 DOI: 10.1111/J.1742-4658.2011.08218.X |
0.739 |
|
| 2011 |
Garwood CJ, Pooler AM, Atherton J, Hanger DP, Noble W. Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture. Cell Death & Disease. 2: e167. PMID 21633390 DOI: 10.1038/Cddis.2011.50 |
0.797 |
|
| 2010 |
Garwood CJ, Cooper JD, Hanger DP, Noble W. Anti-inflammatory impact of minocycline in a mouse model of tauopathy. Frontiers in Psychiatry. 1: 136. PMID 21423446 DOI: 10.3389/Fpsyt.2010.00136 |
0.814 |
|
| 2010 |
Noble W, Burns MP. Challenges in neurodegeneration research. Frontiers in Psychiatry. 1: 7. PMID 21423419 DOI: 10.3389/Fpsyt.2010.00007 |
0.647 |
|
| 2010 |
Noble W, Hanger DP, Gallo JM. Transgenic mouse models of tauopathy in drug discovery. Cns & Neurological Disorders Drug Targets. 9: 403-28. PMID 20522014 DOI: 10.2174/187152710791556131 |
0.709 |
|
| 2010 |
Garwood CJ, Hanger DP, Noble W. P1-315: Minocycline-mediated protection from Aβ is mediated primarily by suppression of astrocytic inflammatory responses Alzheimer's & Dementia. 6: S264-S265. DOI: 10.1016/J.Jalz.2010.05.868 |
0.737 |
|
| 2009 |
Hanger DP, Seereeram A, Noble W. Mediators of tau phosphorylation in the pathogenesis of Alzheimer's disease. Expert Review of Neurotherapeutics. 9: 1647-66. PMID 19903024 DOI: 10.1586/Ern.09.104 |
0.76 |
|
| 2009 |
Wray S, Noble W. Linking amyloid and tau pathology in Alzheimer's disease: the role of membrane cholesterol in Abeta-mediated tau toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9665-7. PMID 19657019 DOI: 10.1523/Jneurosci.2234-09.2009 |
0.686 |
|
| 2009 |
Lebouvier T, Scales TM, Williamson R, Noble W, Duyckaerts C, Hanger DP, Reynolds CH, Anderton BH, Derkinderen P. The microtubule-associated protein tau is also phosphorylated on tyrosine. Journal of Alzheimer's Disease : Jad. 18: 1-9. PMID 19542604 DOI: 10.3233/Jad-2009-1116 |
0.72 |
|
| 2009 |
Noble W, Garwood CJ, Hanger DP. Minocycline as a potential therapeutic agent in neurodegenerative disorders characterised by protein misfolding. Prion. 3: 78-83. PMID 19458490 DOI: 10.4161/Pri.3.2.8820 |
0.748 |
|
| 2009 |
Hanger DP, Anderton BH, Noble W. Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends in Molecular Medicine. 15: 112-9. PMID 19246243 DOI: 10.1016/J.Molmed.2009.01.003 |
0.775 |
|
| 2009 |
Noble W, Garwood C, Stephenson J, Kinsey AM, Hanger DP, Anderton BH. Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 739-50. PMID 19001528 DOI: 10.1096/Fj.08-113795 |
0.834 |
|
| 2008 |
Noble W, Garwood C, Hanger DP, Anderton BH. P3-342: Amyloid-mediated NCX3 cleavage by calpain is an early and toxic event Alzheimer's & Dementia. 4: T622-T622. DOI: 10.1016/J.Jalz.2008.05.1911 |
0.745 |
|
| 2008 |
Garwood CJ, Anderton BH, Hanger DP, Noble W. P2-381: Minocycline reduces caspase-3 activation and prevents cleavage and aggregation of Tau in vivo Alzheimer's & Dementia. 4: T484-T484. DOI: 10.1016/J.Jalz.2008.05.1459 |
0.77 |
|
| 2007 |
Kelleher I, Garwood C, Hanger DP, Anderton BH, Noble W. Kinase activities increase during the development of tauopathy in htau mice. Journal of Neurochemistry. 103: 2256-67. PMID 17908241 DOI: 10.1111/J.1471-4159.2007.04930.X |
0.813 |
|
| 2007 |
Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, et al. Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression. Journal of Neurochemistry. 103: 1132-44. PMID 17683481 DOI: 10.1111/J.1471-4159.2007.04829.X |
0.796 |
|
| 2007 |
Gallo JM, Noble W, Martin TR. RNA and protein-dependent mechanisms in tauopathies: Consequences for therapeutic strategies Cellular and Molecular Life Sciences. 64: 1701-1714. PMID 17453144 DOI: 10.1007/S00018-007-6513-4 |
0.58 |
|
| 2006 |
Currais A, Malik B, Noble W, Towlson C, Soriano S. AbstractPoster presentation: Tuesday posterP3-410: Analysis of the role of presenilin 1 on tau homeostasis Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1681 |
0.472 |
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| 2006 |
Noble W, Hanger DP, Anderton BH. O2-05-07: Minocycline reduces tau phosphorylation and protects against Aβ-induced neurotoxicity Alzheimer's & Dementia. 2: S41-S42. DOI: 10.1016/J.Jalz.2006.05.144 |
0.691 |
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| 2005 |
Utton MA, Noble WJ, Hill JE, Anderton BH, Hanger DP. Molecular motors implicated in the axonal transport of tau and alpha-synuclein. Journal of Cell Science. 118: 4645-54. PMID 16176937 DOI: 10.1242/jcs.02558 |
0.598 |
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| 2005 |
Derkinderen P, Scales TM, Hanger DP, Leung KY, Byers HL, Ward MA, Lenz C, Price C, Bird IN, Perera T, Kellie S, Williamson R, Noble W, Van Etten RA, Leroy K, et al. Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6584-93. PMID 16014719 DOI: 10.1523/Jneurosci.1487-05.2005 |
0.727 |
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| 2005 |
Noble W, Planel E, Zehr C, Olm V, Meyerson J, Suleman F, Gaynor K, Wang L, LaFrancois J, Feinstein B, Burns M, Krishnamurthy P, Wen Y, Bhat R, Lewis J, et al. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 6990-5. PMID 15867159 DOI: 10.1073/Pnas.0500466102 |
0.785 |
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| 2004 |
Noble WJ, Utton MA, Anderton BH, Hanger DP. P3-258 Molecular motors implicated in the fast axonal transport of tau Neurobiology of Aging. 25: S428. DOI: 10.1016/S0197-4580(04)81408-8 |
0.552 |
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| 2004 |
Noble WJ, Derkinderen P, Scales T, Price C, Bird IN, Kellie S, Varndell IM, Sheppard PW, Williamson R, Reynolds H, Anderton BH. P3-226 The microtubule-associated protein tau is phosphorylated on tyrosine 394 Neurobiology of Aging. 25: S419. DOI: 10.1016/S0197-4580(04)81376-9 |
0.359 |
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| 2004 |
Williamson R, Noble W, Kinsey AM, Hye A, Anderton B. P1-293 Rapid lipid RAFT reorganisation and tyrosine phosphorylation of lipid RAFT components in response to amyloid-B peptide-treatment of primary neuronal cultures: involvement of FYN Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80606-7 |
0.376 |
|
| 2004 |
Duff K, Noble W. S3-01-01 Symposia session Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80151-9 |
0.447 |
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| 2003 |
Burns M, Gaynor K, Olm V, Mercken M, LaFrancois J, Wang L, Mathews PM, Noble W, Matsuoka Y, Duff K. Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5645-9. PMID 12843267 |
0.719 |
|
| 2003 |
Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K, LaFrancois J, Wang L, Kondo T, Davies P, Burns M, Veeranna, Nixon R, Dickson D, et al. Cdk5 is a key factor in tau aggregation and tangle formation in vivo. Neuron. 38: 555-65. PMID 12765608 DOI: 10.1016/S0896-6273(03)00259-9 |
0.809 |
|
| 2003 |
Burns MP, Noble WJ, Olm V, Gaynor K, Casey E, LaFrancois J, Wang L, Duff K. Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques. Brain Research. Molecular Brain Research. 110: 119-25. PMID 12573540 DOI: 10.1016/S0169-328X(02)00647-2 |
0.7 |
|
| 2003 |
Burns M, Gaynor K, Olm V, Mercken M, LaFrancois J, Wang L, Mathews PM, Noble W, Matsuoka Y, Duff K. Presenilin Redistribution Associated with Aberrant Cholesterol Transport Enhances β-Amyloid Production In Vivo The Journal of Neuroscience. 23: 5645-5649. DOI: 10.1523/Jneurosci.23-13-05645.2003 |
0.69 |
|
| 2002 |
Duff K, Noble W, Gaynor K, Matsuoka Y. Organotypic slice cultures from transgenic mice as disease model systems. Journal of Molecular Neuroscience : Mn. 19: 317-20. PMID 12540058 DOI: 10.1385/Jmn:19:3:317 |
0.638 |
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