Year |
Citation |
Score |
2018 |
Zhao X, Kedei N, Michalowski AM, Lewin NE, Keck GE, Blumberg PM. Deletion of the C-26 Methyl Substituent from the Bryostatin Analogue Merle 23 has Negligible Impact on Its Biological Profile or Potency. Chembiochem : a European Journal of Chemical Biology. PMID 29517836 DOI: 10.1002/Cbic.201700677 |
0.393 |
|
2018 |
Cummins TJ, Kedei N, Czikora A, Lewin NE, Kirk S, Petersen ME, McGowan KM, Chen JQ, Luo X, Johnson RC, Ravichandran S, Blumberg PM, Keck GE. Synthesis and Biological Evaluation of Fluorescent Bryostatin Analogues. Chembiochem : a European Journal of Chemical Biology. PMID 29424951 DOI: 10.1002/Cbic.201700655 |
0.641 |
|
2016 |
Petersen ME, Kedei N, Lewin NE, Blumberg PM, Keck GE. Replacement of the Bryostatin A- and B-Pyran Rings With Phenyl Rings Leads to Loss of High Affinity Binding With PKC. Tetrahedron Letters. 57: 4749-4753. PMID 27713589 DOI: 10.1016/J.Tetlet.2016.09.040 |
0.686 |
|
2016 |
Baumann DO, McGowan KM, Kedei N, Peach ML, Blumberg PM, Keck GE. Synthesis and Biological Evaluation of Several Bryostatin Analogues Bearing a Diacylglycerol Lactone C-ring. The Journal of Organic Chemistry. PMID 27494208 DOI: 10.1021/Acs.Joc.6B01516 |
0.364 |
|
2016 |
Kelsey JS, Cataisson C, Chen J, Herrmann MA, Petersen ME, Baumann DA, McGowan KM, Yuspa SH, Keck GE, Blumberg PM. Biological activity of the bryostatin analog Merle 23 on mouse epidermal cells and mouse skin. Molecular Carcinogenesis. PMID 26859836 DOI: 10.1002/Mc.22460 |
0.643 |
|
2015 |
Kedei N, Kraft MB, Keck GE, Herald CL, Melody N, Pettit GR, Blumberg PM. Neristatin 1 provides critical insight into bryostatin 1 structure-function relationships. Journal of Natural Products. 78: 896-900. PMID 25808573 DOI: 10.1021/Acs.Jnatprod.5B00094 |
0.722 |
|
2014 |
Kraft MB, Poudel YB, Kedei N, Lewin NE, Peach ML, Blumberg PM, Keck GE. Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core. Journal of the American Chemical Society. 136: 13202-8. PMID 25207434 DOI: 10.1021/Ja5078188 |
0.798 |
|
2014 |
Kedei N, Chen JQ, Herrmann MA, Telek A, Goldsmith PK, Petersen ME, Keck GE, Blumberg PM. Molecular systems pharmacology: isoelectric focusing signature of protein kinase Cδ provides an integrated measure of its modulation in response to ligands. Journal of Medicinal Chemistry. 57: 5356-69. PMID 24906106 DOI: 10.1021/Jm500417B |
0.64 |
|
2014 |
Kelsey J, Kedei N, Cataisson C, Petersen M, Yuspa S, Keck G, Blumberg P. Abstract 1642: Bryostatin 1 and the simplified analog Merle 23 have similar and opposing properties on mouse epidermal cells and mouse skin Cancer Research. 74: 1642-1642. DOI: 10.1158/1538-7445.Am2014-1642 |
0.657 |
|
2013 |
Kedei N, Lewin NE, Géczy T, Selezneva J, Braun DC, Chen J, Herrmann MA, Heldman MR, Lim L, Mannan P, Garfield SH, Poudel YB, Cummins TJ, Rudra A, Blumberg PM, ... Keck GE, et al. Biological profile of the less lipophilic and synthetically more accessible bryostatin 7 closely resembles that of bryostatin 1. Acs Chemical Biology. 8: 767-77. PMID 23369356 DOI: 10.1021/Cb300671S |
0.783 |
|
2013 |
Kedei N, Telek A, Michalowski AM, Kraft MB, Li W, Poudel YB, Rudra A, Petersen ME, Keck GE, Blumberg PM. Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogs in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action. Biochemical Pharmacology. 85: 313-24. PMID 23146662 DOI: 10.1016/J.Bcp.2012.10.028 |
0.764 |
|
2013 |
Kelsey J, Kedei N, Cataisson C, Petersen M, Yuspa S, Keck G, Blumberg P. Abstract 2454: Comparison of the activity of the bryostatin derivative Merle 23 with that of bryostatin 1 and phorbol ester in mouse epidermal cells. Cancer Research. 73: 2454-2454. DOI: 10.1158/1538-7445.Am2013-2454 |
0.675 |
|
2013 |
Kedei N, Michalowski AM, Petersen ME, Keck GE, Blumberg PM. Abstract 2101: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogue in LNCaP and U937 cells provides insight into their differential mechanism. Cancer Research. 73: 2101-2101. DOI: 10.1158/1538-7445.Am2013-2101 |
0.649 |
|
2012 |
Keck GE, Poudel YB, Rudra A, Stephens JC, Kedei N, Lewin NE, Blumberg PM. Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity. Bioorganic & Medicinal Chemistry Letters. 22: 4084-8. PMID 22579485 DOI: 10.1016/J.Bmcl.2012.04.073 |
0.798 |
|
2012 |
Kedei N, Telek A, Michalowski AM, Kraft MB, Li W, Poudel YB, Rudra A, Petersen ME, Keck GE, Blumberg PM. Abstract 3815: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogues in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action Cancer Research. 72: 3815-3815. DOI: 10.1158/1538-7445.Am2012-3815 |
0.765 |
|
2011 |
Kedei N, Lubart E, Lewin NE, Telek A, Lim L, Mannan P, Garfield SH, Kraft MB, Keck GE, Kolusheva S, Jelinek R, Blumberg PM. Some phorbol esters might partially resemble bryostatin 1 in their actions on LNCaP prostate cancer cells and U937 leukemia cells. Chembiochem : a European Journal of Chemical Biology. 12: 1242-51. PMID 21542090 DOI: 10.1002/Cbic.201100064 |
0.754 |
|
2011 |
Kedei N, Telek A, Czap A, Lubart ES, Czifra G, Yang D, Chen J, Morrison T, Goldsmith PK, Lim L, Mannan P, Garfield SH, Kraft MB, Li W, Keck GE, et al. The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line. Biochemical Pharmacology. 81: 1296-308. PMID 21458422 DOI: 10.1016/J.Bcp.2011.03.018 |
0.766 |
|
2011 |
Keck GE, Poudel YB, Cummins TJ, Rudra A, Covel JA. Total synthesis of bryostatin 1. Journal of the American Chemical Society. 133: 744-7. PMID 21175177 DOI: 10.1021/Ja110198Y |
0.816 |
|
2011 |
Keck GE, Poudel YB, Cummins TJ, Rudra A, Covel JA. Synthesis of Bryostatin 1 Synfacts. 2011: 464-464. DOI: 10.1055/S-0030-1259787 |
0.79 |
|
2010 |
Keck GE, Poudel YB, Rudra A, Stephens JC, Kedei N, Lewin NE, Peach ML, Blumberg PM. Molecular modeling, total synthesis, and biological evaluations of C9-deoxy bryostatin 1. Angewandte Chemie (International Ed. in English). 49: 4580-4. PMID 20491108 DOI: 10.1002/Anie.201001200 |
0.773 |
|
2010 |
Kedei N, Telek A, Czifra G, Czap A, Chen J, Goldsmith PK, Keck GE, Blumberg PM. Abstract 4500: What distinguishes a PKC activator like phorbol ester from a PKC functional antagonist like bryostatin 1? Bryologues permit mechanistic insight Cancer Research. 70: 4500-4500. DOI: 10.1158/1538-7445.Am10-4500 |
0.315 |
|
2009 |
Keck GE, Li W, Kraft MB, Kedei N, Lewin NE, Blumberg PM. The bryostatin 1 A-ring acetate is not the critical determinant for antagonism of phorbol ester-induced biological responses. Organic Letters. 11: 2277-80. PMID 19419164 DOI: 10.1021/Ol900585T |
0.798 |
|
2009 |
Keck GE, Poudel YB, Welch DS, Kraft MB, Truong AP, Stephens JC, Kedei N, Lewin NE, Blumberg PM. Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters. Organic Letters. 11: 593-6. PMID 19113896 DOI: 10.1021/Ol8027253 |
0.794 |
|
2008 |
Keck GE, Giles RL, Cee VJ, Wager CA, Yu T, Kraft MB. Total synthesis of epothilones B and D: stannane equivalents for beta-keto ester dianions. The Journal of Organic Chemistry. 73: 9675-91. PMID 18991385 DOI: 10.1021/Jo802215V |
0.794 |
|
2008 |
Keck GE, Heumann SA. Diastereoselective synthesis of cyclopentapyridazinones via radical cyclization: synthetic studies toward halichlorine. Organic Letters. 10: 4783-6. PMID 18816137 DOI: 10.1021/Ol801849U |
0.413 |
|
2008 |
Heumann LV, Keck GE. A new method for the synthesis of H(4)-BINOL. The Journal of Organic Chemistry. 73: 4725-7. PMID 18489159 DOI: 10.1021/Jo8004556 |
0.77 |
|
2008 |
Keck GE, Kraft MB, Truong AP, Li W, Sanchez CC, Kedei N, Lewin NE, Blumberg PM. Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: bryostatin look-alikes that mimic phorbol ester function. Journal of the American Chemical Society. 130: 6660-1. PMID 18452293 DOI: 10.1021/Ja8022169 |
0.816 |
|
2007 |
Heumann LV, Keck GE. A catalytic asymmetric vinylogous Mukaiyama aldol reaction. Organic Letters. 9: 4275-8. PMID 17887693 DOI: 10.1021/Ol701851F |
0.786 |
|
2007 |
Heumann LV, Keck GE. A new construction of 2-alkoxypyrans by an acylation-reductive cyclization sequence. Organic Letters. 9: 1951-4. PMID 17428064 DOI: 10.1021/Ol070573H |
0.789 |
|
2006 |
Keck GE, Welch DS, Poudel YB. Synthetic Studies Toward Bryostatin 1: Preparation of a C(1)-C(16) Fragment by Pyran Annulation. Tetrahedron Letters. 47: 8267-8270. PMID 17404602 DOI: 10.1016/J.Tetlet.2006.09.094 |
0.807 |
|
2006 |
Keck GE, Welch DS, Vivian PK. Synthetic studies toward the bryostatins: a substrate-controlled approach to the A-ring. Organic Letters. 8: 3667-70. PMID 16898787 DOI: 10.1021/Ol061173H |
0.811 |
|
2005 |
Keck GE, McLaws MD. Stereoselective synthesis of the C(1)-C(13) segment of dolabelide B. Tetrahedron Letters. 46: 4911-4914. PMID 16909163 DOI: 10.1016/J.Tetlet.2005.04.146 |
0.801 |
|
2005 |
Sanchez CC, Keck GE. Total synthesis of (+)-dactylolide. Organic Letters. 7: 3053-6. PMID 15987203 DOI: 10.1021/Ol051040G |
0.732 |
|
2005 |
Keck GE, Truong AP. Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core. Organic Letters. 7: 2153-6. PMID 15901157 DOI: 10.1021/Ol050512O |
0.732 |
|
2005 |
Keck GE, Truong AP. Synthetic studies on the bryostatins: preparation of a truncated BC-ring intermediate by pyran annulation. Organic Letters. 7: 2149-52. PMID 15901156 DOI: 10.1021/Ol050511W |
0.75 |
|
2005 |
Keck GE, Yu T, McLaws MD. Enantio- and diastereoselective additions to aldehydes using the bifunctional reagent 2-(chloromethyl)-3-(tributylstannyl)propene: application to a synthesis of the C16-C27 segment of bryostatin 1. The Journal of Organic Chemistry. 70: 2543-50. PMID 15787541 DOI: 10.1021/Jo048308M |
0.83 |
|
2003 |
Keck GE, Krishnamurthy D. Catalytic Asymmetric Allylation Reactions:(S)‐1‐(Phenylmethoxy)‐4‐Penten‐2‐ol Organic Syntheses. 12-12. DOI: 10.1002/0471264180.Os075.02 |
0.37 |
|
2002 |
Keck GE, Welch DS. Intramolecular Baylis-Hillman and morita reactions using unsaturated thiol ester substrates containing enolizable aldehydes. Organic Letters. 4: 3687-90. PMID 12375919 DOI: 10.1021/Ol026638S |
0.794 |
|
2002 |
Keck GE, Truong AP. Directed reduction of beta-amino ketones to syn or anti 1,3-amino alcohol derivatives. Organic Letters. 4: 3131-4. PMID 12201734 DOI: 10.1021/Ol026456Y |
0.675 |
|
2002 |
Keck GE, Covel JA, Schiff T, Yu T. Pyran annulation: asymmetric synthesis of 2,6-disubstituted-4-methylene tetrahydropyrans. Organic Letters. 4: 1189-92. PMID 11922815 DOI: 10.1021/Ol025645D |
0.794 |
|
2001 |
Keck GE, Wager CA, Wager TT, Savin KA, Covel JA, McLaws MD, Krishnamurthy D, Cee VJ. Asymmetric Total Synthesis of Rhizoxin D. Angewandte Chemie (International Ed. in English). 40: 231-234. PMID 29711955 DOI: 10.1002/1521-3773(20010105)40:1<231::Aid-Anie231>3.0.Co;2-W |
0.786 |
|
2001 |
Keck GE, Knutson CE, Wiles SA. Total synthesis of the immunosupressant (-)-pironetin (PA48153C). Organic Letters. 3: 707-10. PMID 11259042 DOI: 10.1021/Ol015531M |
0.814 |
|
2001 |
Keck GE, Wager CA, Wager TT, Savin KA, Covel JA, McLaws MD, Krishnamurthy D, Cee VJ. Asymmetric Total Synthesis of Rhizoxin D Financial support has been provided by the National Institutes of Health (through grant GM-28961) and by Pfizer, Inc. Angewandte Chemie (International Ed. in English). 40: 231-234. PMID 11169722 DOI: 10.1002/1521-3773(20010105)40:1<231::AID-ANIE231>3.0.CO;2-W |
0.76 |
|
2000 |
Keck GE, Wager CA. The first directed reduction of beta-alkoxy ketones to anti-1,3-diol monoethers: identification of spectator and director alkoxy groups. Organic Letters. 2: 2307-9. PMID 10930270 DOI: 10.1021/Ol006072C |
0.313 |
|
2000 |
Keck GE, Sanchez C, Wager CA. Macrolactonization of hydroxy acids using a polymer bound carbodiimide Tetrahedron Letters. 41: 8673-8676. DOI: 10.1016/S0040-4039(00)01569-0 |
0.647 |
|
2000 |
Keck GE, McLaws MD, Wager TT. A direct and mild conversion of tertiary aryl amides to methyl esters using trimethyloxonium tetrafluoroborate: A very useful complement to directed metalation reactions Tetrahedron. 56: 9875-9883. DOI: 10.1016/S0040-4020(00)00969-8 |
0.797 |
|
1999 |
Keck GE, Li XY, Knutson CE. A versatile preparation of alpha,beta-unsaturated lactones from homoallylic alcohols. Organic Letters. 1: 411-3. PMID 10822582 DOI: 10.1021/Ol990632U |
0.794 |
|
1999 |
Keck GE, Yu T. Catalytic asymmetric allylation reactions using BITIP catalysis and 2-substituted allylstannanes as surrogates for beta-keto ester dianions. Organic Letters. 1: 289-91. PMID 10822564 DOI: 10.1021/Ol990603J |
0.397 |
|
1999 |
Keck GE, Lundquist GD. Synthetic studies toward the total synthesis of swinholide 1. Stereoselective construction of the C19-C35 subunit Journal of Organic Chemistry. 64: 4482-4491. DOI: 10.1021/Jo990291Y |
0.427 |
|
1999 |
Keck GE, McHardy SF, Murry JA. Diastereoselective 6-exo radical cyclizations of oxime ethers: Total synthesis of 7-deoxypancratistatin Journal of Organic Chemistry. 64: 4465-4476. DOI: 10.1021/Jo9902042 |
0.441 |
|
1999 |
Keck GE, Wager TT, Duarte Rodriquez JF. Total syntheses of (-)-lycoricidine, (+)-lycoricidine, and (+)- narciclasine via 6-exo cyclizations of substituted vinyl radicals with oxime ethers Journal of the American Chemical Society. 121: 5176-5190. DOI: 10.1021/Ja9826688 |
0.374 |
|
1999 |
Keck GE, Wager TT, McHardy SF. Reductive cleavage of N-O bonds in hydroxylamines and hydroxamic acid derivatives using samarium diiodide Tetrahedron. 55: 11755-11772. DOI: 10.1016/S0040-4020(99)00486-X |
0.352 |
|
1998 |
Keck GE, Wager TT, McHardy SF. A second-generation radical-based synthesis of (+)-7- deoxypancratistatin Journal of Organic Chemistry. 63: 9164-9165. DOI: 10.1021/Jo981890S |
0.33 |
|
1996 |
Keck GE, Krishnamurthy D. A simple and practical synthesis of (+)-2-bromobicyclo[2.2.1]hept-5-ene-2-carboxaldehyde via chiral Lewis acid catalyzed [4+2] cycloaddition Synthetic Communications. 26: 367-373. DOI: 10.1080/00397919608003625 |
0.397 |
|
1996 |
Keck GE, Wager TT. Total synthesis of ent-lycoricidine via a thiyl radical addition-cyclization sequence Journal of Organic Chemistry. 61: 8366-8367. DOI: 10.1021/Jo961619F |
0.346 |
|
1996 |
Keck GE, Savin KA, Weglarz MA, Cressman ENK. Synthetic studies on the rhizoxins. II. An approach to the C10-C26 subunit using "substrate directed" allylstannane additions to aldehydes Tetrahedron Letters. 37: 3291-3294. DOI: 10.1016/0040-4039(96)00578-3 |
0.395 |
|
1995 |
Keck GE, Li XY, Krishnamurthy D. Catalytic enantioselective synthesis of dihydropyrones via formal hetero Diels-Alder reactions of "Danishefsky's diene" with aldehydes Journal of Organic Chemistry. 60: 5998-5999. DOI: 10.1021/Jo00124A001 |
0.415 |
|
1995 |
Keck GE, McHardy SF, Murry JA. Total synthesis of (+)-7-deoxypancratistatin: A radical cyclization approach Journal of the American Chemical Society. 117: 7289-7290. DOI: 10.1021/Ja00132A047 |
0.368 |
|
1995 |
Keck GE, Dougherty SM, Savin KA. Intramolecular allylstannane-aldehyde cyclizations: Stereochemical results with flexible tethers for reactions forming vinylcyclohexanols Journal of the American Chemical Society. 117: 6210-6217. DOI: 10.1021/Ja00128A007 |
0.388 |
|
1995 |
Keck GE, McHardy SF, Wager TT. Reductive cleavage of NO bonds in hydroxylamine and hydroxamic acid derivatives using SmI2/THF Tetrahedron Letters. 36: 7419-7422. DOI: 10.1016/0040-4039(95)01557-4 |
0.327 |
|
1994 |
Keck GE, Savin KA, Cressman ENK, Abbott DE. Effects of olefin geometry on the stereochemistry of Lewis acid mediated additions of crotylstannanes to aldehydes Journal of Organic Chemistry. 59: 7889-7896. DOI: 10.1021/Jo00104A054 |
0.329 |
|
1994 |
Keck GE, Palani A, McHardy SF. Total synthesis of (+)-carbonolide B Journal of Organic Chemistry. 59: 3113-3122. DOI: 10.1021/Jo00090A032 |
0.41 |
|
1994 |
Keck GE, Krishnamurthy D, Chen X. Asymmetric synthesis of homopropargylic alcohols from aldehydes and allenyltri-n-butylstannane Tetrahedron Letters. 35: 8323-8324. DOI: 10.1016/S0040-4039(00)74397-8 |
0.316 |
|
1993 |
Keck GE, Krishnamurthy D, Grier MC. Catalytic asymmetric allylation reactions. 3. Extension to methallylstannane, comparison of procedures, and observation of a nonlinear effect Journal of Organic Chemistry. 58: 6543-6544. DOI: 10.1021/Jo00076A005 |
0.35 |
|
1993 |
Keck GE, Romer DR. An acylnitroso cycloaddition approach to the synthesis of highly oxygenated indolizidine alkaloids Journal of Organic Chemistry. 58: 6083-6089. DOI: 10.1021/Jo00074A040 |
0.803 |
|
1993 |
Keck GE, Park M, Krishnamurthy D. Synthetic studies on the rhizoxins. 1. Two stereoselective routes to a functionalized C1-C9 subunit Journal of Organic Chemistry. 58: 3787-3788. DOI: 10.1021/Jo00067A003 |
0.388 |
|
1993 |
Keck GE, Tarbet KH, Geraci LS. Catalytic asymmetric allylation of aldehydes Journal of the American Chemical Society. 115: 8467-8468. DOI: 10.1021/Ja00071A074 |
0.373 |
|
1993 |
Keck GE, Kordik CP. A three component free radical coupling reaction: Vicinal dialkylation of α,β-unsaturated ketones and esters Tetrahedron Letters. 34: 6875-6876. DOI: 10.1016/S0040-4039(00)91818-5 |
0.349 |
|
1993 |
Keck GE, McHardy SF, Murry JA. Some unusual reactions of weinreb amides Tetrahedron Letters. 34: 6215-6218. DOI: 10.1016/S0040-4039(00)73713-0 |
0.325 |
|
1993 |
Keck GE, Palani A. A conjunctive approach to the synthesis of functionalized piperidines from imines Tetrahedron Letters. 34: 3223-3224. DOI: 10.1016/S0040-4039(00)73666-5 |
0.349 |
|
1993 |
Keck GE, Geraci LS. Catalytic asymmetric allylation (CAA) reactions. II. A new enantioselective allylation procedure Tetrahedron Letters. 34: 7827-7828. DOI: 10.1016/S0040-4039(00)61486-7 |
0.399 |
|
1993 |
Keck GE, Tonnies SD. Intramolecular allylstannane-carbonyl condensations. Formation of vinylcyclopropane derivatives and an unusual dimeric product Tetrahedron Letters. 34: 4607-4610. DOI: 10.1016/S0040-4039(00)60636-6 |
0.392 |
|
1991 |
Keck GE, Murry JA. Total synthesis of (-)-colletol Journal of Organic Chemistry. 56: 6606-6611. DOI: 10.1021/Jo00023A029 |
0.396 |
|
1991 |
Keck GE, Andrus MB, Romer DR. A useful new enantiomerically pure synthon from malic acid: Chelation-controlled activation as a route to regioselectivity Journal of Organic Chemistry. 56: 417-420. DOI: 10.1021/Jo00001A076 |
0.773 |
|
1990 |
Keck GE, Tafesh AM. Radical Cyclization Reactions from α-Silyloxy Phenylselenides: An Alternative to Acyl Radicals Synlett. 1990: 257-258. DOI: 10.1055/S-1990-21054 |
0.3 |
|
1989 |
Keck GE, Tafesh AM. Free-radical addition-fragmentation reactions in synthesis: A "second generation" synthesis of (+)-pseudomonic acid C Journal of Organic Chemistry. 54: 5845-5846. DOI: 10.1021/Jo00286A008 |
0.328 |
|
1989 |
Keck GE, Cressman ENK, Enholm EJ. Intramolecular allylstannane cyclizations in alkaloid synthesis: Applications to pyrrolizidine alkaloids Journal of Organic Chemistry. 54: 4345-4349. DOI: 10.1021/Jo00279A022 |
0.307 |
|
1989 |
Keck GE, Boden EP, Wiley MR. Total synthesis of (+)-colletodiol: New methodology for the synthesis of macrolactones Journal of Organic Chemistry. 54: 896-906. DOI: 10.1021/Jo00265A033 |
0.4 |
|
1989 |
Keck GE, Andrus MB, Castellino S. The mechanism of tin tetrachloride promoted additions of allylstannanes to aldehydes: a response to Denmark, Wilson, and Willson Journal of the American Chemical Society. 111: 8136-8141. DOI: 10.1021/Ja00203A012 |
0.628 |
|
1989 |
Keck GE, Andrus MB, Castellino S. On the mechanism of SnCl4-promoted additions of allylstannanes to aldehydes: A response to Denmark, Wilson, and Willson Journal of the American Chemical Society. 111: 8136-8141. |
0.585 |
|
1988 |
Keck GE, Byers JH, Tafesh AM. A free radical addition-fragmentation reaction for the preparation of vinyl sulfones and phosphine oxides Journal of Organic Chemistry. 53: 1127-1128. DOI: 10.1021/Jo00240A049 |
0.302 |
|
1987 |
Keck GE, Burnett DA. β-Stannyl enones as radical traps: A very direct route to PGF2α Journal of Organic Chemistry. 52: 2958-2960. DOI: 10.1021/Jo00389A069 |
0.554 |
|
1987 |
Keck GE, Abbott DE, Wiley MR. New allylstannanes for the connective construction of monoprotected vicinal diols Tetrahedron Letters. 28: 139-142. DOI: 10.1016/S0040-4039(00)95669-7 |
0.359 |
|
1986 |
Keck GE, Kachensky DF. A highly convergent total synthesis of (+)-compactin Journal of Organic Chemistry. 51: 2487-2493. DOI: 10.1021/Jo00363A016 |
0.392 |
|
1985 |
Keck GE, Enholm EJ. Synthetic studies on pyrrolizidine alkaloids. II. Intramolecular additions of radicals and electrophiles to allylstannanes as methods for ring closure Tetrahedron Letters. 26: 3311-3314. DOI: 10.1016/S0040-4039(00)98285-6 |
0.377 |
|
1985 |
Keck GE, Enholm EJ, Yates JB, Wiley MR. One electron C-C bond forming reactions VIA allylstannanes: Scope and limitations Tetrahedron. 41: 4079-4094. DOI: 10.1016/S0040-4020(01)97185-6 |
0.363 |
|
1985 |
Keck GE, Boden EP, Mabury SA. A useful Wittig reagent for the stereoselective synthesis of trans α,β-unsaturated thiol esters Journal of Organic Chemistry. 50: 709-710. DOI: 10.1002/Chin.198531180 |
0.316 |
|
1984 |
Keck GE, Abbott DE. Stereochemical consequences for the Lewis acid mediated additions of allyl and crotyltri-n-butylstannane to chiral β-hydroxyaldehyde derivatives Tetrahedron Letters. 25: 1883-1886. DOI: 10.1016/S0040-4039(01)90066-8 |
0.34 |
|
1984 |
Keck GE, Enholm EJ, Kachensky DF. Two new methods for the synthesis of C-glycosides Tetrahedron Letters. 25: 1867-1870. DOI: 10.1016/S0040-4039(01)90062-0 |
0.419 |
|
1984 |
Keck GE, Boden EP. Stereocontrolled additions of allyltri-n-butyl-stannane to α-hydroxyaldehyde derivatives. A useful route to monoprotected erythro or threo diols. Tetrahedron Letters. 25: 265-268. DOI: 10.1016/S0040-4039(00)99857-5 |
0.353 |
|
1984 |
Keck GE, Abbott DE, Boden EP, Enholm EJ. Observations on the choice of Lewis acid and mode of addition for the Lewis acid mediated reaction of crotyltri-n-butylstannane with aldehydes: convenient and highly selective access to both erythro and threo products Tetrahedron Letters. 25: 3927-3930. DOI: 10.1016/0040-4039(84)80032-5 |
0.346 |
|
1984 |
Keck GE, Kachensky DF, Enholm EJ. Total synthesis of pseudomonic acid C Journal of Organic Chemistry. 49: 1462-1464. DOI: 10.1002/Chin.198439312 |
0.397 |
|
1982 |
Keck GE, Webb RR. A versatile method for the preparation of allenic alcohols Tetrahedron Letters. 23: 3051-3054. DOI: 10.1016/S0040-4039(00)87530-9 |
0.302 |
|
1982 |
Keck GE, Yates JB. A novel synthesis of (.+-.)-perhydrohistrionicotoxin The Journal of Organic Chemistry. 47: 3590-3591. DOI: 10.1002/Chin.198305337 |
0.408 |
|
1982 |
Keck GE, Webb RR. Alkaloid synthesis via intramolecular ene reaction. 2. Application to dl-mesembrine and dl-dihydromaritidine Journal of Organic Chemistry. 47: 1302-1309. DOI: 10.1002/Chin.198239363 |
0.398 |
|
1981 |
Keck GE, Webb RR. Alkaloid synthesis via intramolecular ene reactions. 1. Application to (.+-.)-crinane Journal of the American Chemical Society. 103: 3173-3177. DOI: 10.1021/Ja00401A039 |
0.406 |
|
1981 |
Keck GE, Boden E, Sonnewald U. Synthetic studies on lycoridicine. II. An effect route to cis dihydrolycoricidine Tetrahedron Letters. 22: 2615-2618. DOI: 10.1016/S0040-4039(01)92951-X |
0.322 |
|
1981 |
Keck GE, Webb RR, Yates JB. A versatile method for carbon-nitrogen bond formation via ene reactions of acylnitroso compounds Tetrahedron. 37: 4007-4016. DOI: 10.1016/S0040-4020(01)93275-2 |
0.424 |
|
1981 |
Keck GE, Webb RRI. Alkaloid Synthesis Via Intramolecular Ene Reactions. 1. Application To (.+-.)-Crinane Cheminform. 12. DOI: 10.1002/Chin.198138344 |
0.406 |
|
1979 |
Keck GE, Fleming S, Nickell D, Weider P. Mild and Efficient Methods for the Reductive Cleavage of Nitrogen-Oxygen Bonds Synthetic Communications. 9: 281-286. DOI: 10.1080/00397917908064153 |
0.656 |
|
1979 |
Keck GE, Yates JB. Allylic amidation. An investigation of nitrosocarbonylmethane for direct allylic functionalization of olefins Tetrahedron Letters. 20: 4627-4630. DOI: 10.1016/S0040-4039(01)86667-3 |
0.417 |
|
1979 |
ZIMMERMAN HE, GANNETT TP, KECK GE. ChemInform Abstract: MECHANISTIC AND EXPLORATORY ORGANIC PHOTOCHEMISTRY. 118. STEREOCHEMISTRY OF THE ARYL-VINYL VERSION OF THE DI-Π-METHANE REARRANGEMENT Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197943117 |
0.455 |
|
1979 |
Zimmerman HE, Gannett TP, Keck GE. Mechanistic and exploratory organic photochemistry. 118. Stereochemistry of the aryl-vinyl version of the di-.pi.-methane rearrangement The Journal of Organic Chemistry. 44: 1982-1989. DOI: 10.1002/Chin.197943117 |
0.442 |
|
1979 |
COREY EJ, DANHEISER RL, CHANDRASEKARAN S, KECK GE, GOPALAN B, LARSEN SD, SIRET P, GRAS J. ChemInform Abstract: STEREOSPECIFIC TOTAL SYNTHESIS OF GIBBERELLIC ACID Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197912390 |
0.561 |
|
1979 |
Zimmerman HE, Gannett TP, Keck GE. Stereochemistry of the aryl-vinyl version of the di-π-methane rearrangement Journal of Organic Chemistry. 44: 1982-1989. |
0.505 |
|
1978 |
Corey EJ, Danheiser RL, Chandrasekaran S, Keck GE, Gopalan B, Larsen SD, Siret P, Gras JL. Stereospecific total synthesis of gibberellic acid Journal of the American Chemical Society. 100: 8034-8036. DOI: 10.1021/Ja00493A056 |
0.703 |
|
1978 |
Zimmerman HE, Gannett TP, Keck GE. Stereochemistry in the di-π-methane rearrangement: Aryl migration. Exploratory and mechanistic organic photochemistry [28] Journal of the American Chemical Society. 100: 323-324. DOI: 10.1021/Ja00469A075 |
0.439 |
|
1978 |
Keck GE, Fleming SA. Model studies on Narcissus alkaloids. Synthetic methodology for the synthesis of lycoricidine analogues Tetrahedron Letters. 19: 4763-4766. DOI: 10.1016/S0040-4039(01)85725-7 |
0.687 |
|
1978 |
ZIMMERMAN HE, GANNETT TP, KECK GE. ChemInform Abstract: STEREOCHEMISTRY IN THE DI-Π-METHANE REARRANGEMENT- ARYL MIGRATION. EXPLORATORY AND MECHANISTIC ORGANIC PHOTOCHEMISTRY Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197817106 |
0.446 |
|
1978 |
Corey EJ, Danheiser RL, Chandrasekaran S, Keck GE, Gopalan B, Larsen SD, Siret P, Gras JL. Stereospecific total synthesis of gibberellic acid [24] Journal of the American Chemical Society. 100: 8034-8036. |
0.554 |
|
1978 |
Corey EJ, Danheiser RL, Chandrasekaran S, Siret P, Keck GE, Gras JL. Stereospecific total synthesis of gibberellic acid. A key tricyclic intermediate [23] Journal of the American Chemical Society. 100: 8031-8034. |
0.576 |
|
1977 |
Corey EJ, Keck GE, Szekely I. Synthesis of Vane's prostaglandin X, 6,9alpha-oxido9alpha,15alpha-dihydroxyprosta-(Z)5,(E)13-dienoic acid. Journal of the American Chemical Society. 99: 2006-8. PMID 839023 DOI: 10.1021/Ja00448A069 |
0.313 |
|
1977 |
COREY EJ, KECK GE, SZEKELY I. ChemInform Abstract: SYNTHESIS OF VANE′S PROSTAGLANDIN X, 6,9α-OXIDO-9α,15α-DIHYDROXYPROSTA-(Z)5,(E)13-DIENOIC ACID Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/Chin.197724394 |
0.308 |
|
1976 |
Zimmerman HE, Keck GE, Pflederer JL. Molecular rearrangements of excited states generated by intramolecular dioxetane scission. Photochemistry without light. Mechanistic and exploratory organic photochemistry Journal of the American Chemical Society. 98: 5574-5581. DOI: 10.1021/Ja00434A028 |
0.387 |
|
1976 |
Zimmerman HE, Boettcher RJ, Buehler NE, Keck GE, Steinmetz MG. Independent generation of cyclopropyldicarbinyl diradical species of the Di-π-methane rearrangement. Excited singlet, triplet, and ground-state hypersurfaces of barrelene photochemistry. Mechanistic and exploratory organic photochemistry Journal of the American Chemical Society. 98: 7680-7689. DOI: 10.1002/Chin.197709142 |
0.447 |
|
1975 |
Zimmerman HE, Boettcher RJ, Buehler NE, Keck GE. Generation of photochemical species on ground, excited singlet, and triplet hypersurfaces in barrelene photochemistry [38] Journal of the American Chemical Society. 97: 5635-5637. DOI: 10.1021/Ja00852A081 |
0.35 |
|
1975 |
Zimmerman HE, Keck GE. Photochemical rearrangement without light. 95. Dioxetane effected photochemistry by direct intramolecular excitation Journal of the American Chemical Society. 97: 3527-3528. DOI: 10.1021/Ja00845A047 |
0.395 |
|
1975 |
ZIMMERMAN HE, BOETTCHER RJ, BUEHLER NE, KECK GE. ChemInform Abstract: MECHANISTIC AND EXPLORATORY ORGANIC PHOTOCHEMISTRY PART 98, GENERATION OF PHOTOCHEMICAL SPECIES ON GROUND, EXCITED SINGLET, AND TRIPLET HYPERSURFACES IN BARRELENE PHOTOCHEMISTRY Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197549154 |
0.443 |
|
1975 |
ZIMMERMAN HE, KECK GE. ChemInform Abstract: A PHOTOCHEMICAL REARRANGEMENT WITHOUT LIGHT. DIOXETANE EFFECTED PHOTOCHEMISTRY BY DIRECT INTRAMOLECULAR EXCITATION PART 95 Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197534120 |
0.475 |
|
1975 |
Zimmerman HE, Keck GE. A photochemical rearrangement without light. Dioxetane effected photochemistry by direct intramolecular excitation [11] Journal of the American Chemical Society. 97: 3527-3528. |
0.395 |
|
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