| Year |
Citation |
Score |
| 2021 |
Sun D, Xie XP, Zhang X, Wang Z, Sait SF, Iyer SV, Chen YJ, Brown R, Laks DR, Chipman ME, Shern JF, Parada LF. Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression. Cell Stem Cell. PMID 34010628 DOI: 10.1016/j.stem.2021.04.029 |
0.63 |
|
| 2020 |
Wang Z, Sun D, Chen YJ, Xie X, Shi Y, Tabar V, Brennan CW, Bale TA, Jayewickreme CD, Laks DR, Alcantara Llaguno S, Parada LF. Cell Lineage-Based Stratification for Glioblastoma. Cancer Cell. PMID 32649888 DOI: 10.1016/J.Ccell.2020.06.003 |
0.636 |
|
| 2020 |
Sait SF, Tang K, Brown R, Sun D, Xie X, Neel B, Parada L. Abstract 1889: Allosteric inhibition of SHP2 prevents adaptive resistance to MEK inhibition in neurofibromatosis type 1 associated malignant peripheral nerve sheath tumors Cancer Research. 80: 1889-1889. DOI: 10.1158/1538-7445.Am2020-1889 |
0.34 |
|
| 2019 |
Shi Y, Lim SK, Liang Q, Iyer SV, Wang HY, Wang Z, Xie X, Sun D, Chen YJ, Tabar V, Gutin P, Williams N, De Brabander JK, Parada LF. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. PMID 30842654 DOI: 10.1038/S41586-019-0993-X |
0.607 |
|
| 2019 |
Llaguno SA, Sun D, Pedraza AM, Vera E, Wang Z, Burns DK, Parada LF. Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction. Nature Neuroscience. PMID 30778149 DOI: 10.1038/S41593-018-0333-8 |
0.303 |
|
| 2018 |
Sun D, Parada L. Abstract B14: A restricted cell population propagates MPNST growth after treatment Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-B14 |
0.315 |
|
| 2017 |
Ma Z, Zang T, Birnbaum SG, Wang Z, Johnson JE, Zhang CL, Parada LF. TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response. Nature Communications. 8: 1668. PMID 29162814 DOI: 10.1038/S41467-017-01709-8 |
0.653 |
|
| 2016 |
Llaguno SA, Wang Z, Sun D, Chen J, Pedraza A, Xu J, Kim E, Hatanpaa K, Raisanen J, Burns D, Johnson J, Parada L. TMOD-07. CELLULAR ORIGINS OF GLIOBLASTOMA: LESSONS FROM MOUSE MODELS Neuro-Oncology. 18: vi208-vi208. DOI: 10.1093/Neuonc/Now212.877 |
0.459 |
|
| 2015 |
Alcantara Llaguno SR, Wang Z, Sun D, Chen J, Xu J, Kim E, Hatanpaa KJ, Raisanen JM, Burns DK, Johnson JE, Parada LF. Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes. Cancer Cell. 28: 429-40. PMID 26461091 DOI: 10.1016/J.Ccell.2015.09.007 |
0.461 |
|
| 2014 |
Anastasia A, Deinhardt K, Wang S, Martin L, Nichol D, Irmady K, Trinh J, Parada L, Rafii S, Hempstead BL, Kermani P. Trkb signaling in pericytes is required for cardiac microvessel stabilization. Plos One. 9: e87406. PMID 24498100 DOI: 10.1371/Journal.Pone.0087406 |
0.357 |
|
| 2014 |
Amiri A, Sanchez-Ortiz E, Cho W, Birnbaum SG, Xu J, McKay RM, Parada LF. Analysis of FMR1 deletion in a subpopulation of post-mitotic neurons in mouse cortex and hippocampus. Autism Research : Official Journal of the International Society For Autism Research. 7: 60-71. PMID 24408886 DOI: 10.1002/aur.1342 |
0.341 |
|
| 2014 |
Haws ME, Jaramillo TC, Espinosa F, Widman AJ, Stuber GD, Sparta DR, Tye KM, Russo SJ, Parada LF, Stavarache M, Kaplitt M, Bonci A, Powell CM. PTEN knockdown alters dendritic spine/protrusion morphology, not density. The Journal of Comparative Neurology. 522: 1171-90. PMID 24264880 DOI: 10.1002/Cne.23488 |
0.518 |
|
| 2013 |
Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, ... Parada LF, et al. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 152: 1077-90. PMID 23434321 DOI: 10.1016/J.Cell.2013.01.053 |
0.327 |
|
| 2012 |
Li Y, Yui D, Luikart BW, McKay RM, Li Y, Rubenstein JL, Parada LF. Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development. Proceedings of the National Academy of Sciences of the United States of America. 109: 15491-6. PMID 22949667 DOI: 10.1073/Pnas.1212899109 |
0.697 |
|
| 2012 |
Chen J, Li Y, Yu TS, McKay RM, Burns DK, Kernie SG, Parada LF. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature. 488: 522-6. PMID 22854781 DOI: 10.1038/Nature11287 |
0.305 |
|
| 2012 |
Sanchez-Ortiz E, Yui D, Song D, Li Y, Rubenstein JL, Reichardt LF, Parada LF. TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4065-79. PMID 22442072 DOI: 10.1523/Jneurosci.6314-11.2012 |
0.327 |
|
| 2012 |
Li Y, Li Y, McKay RM, Riethmacher D, Parada LF. Neurofibromin modulates adult hippocampal neurogenesis and behavioral effects of antidepressants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3529-39. PMID 22399775 DOI: 10.1523/Jneurosci.3469-11.2012 |
0.376 |
|
| 2011 |
Zhou J, Shrikhande G, Xu J, McKay RM, Burns DK, Johnson JE, Parada LF. Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle. Genes & Development. 25: 1595-600. PMID 21828270 DOI: 10.1101/Gad.16750211 |
0.413 |
|
| 2011 |
Luikart BW, Bensen AL, Washburn EK, Perederiy JV, Su KG, Li Y, Kernie SG, Parada LF, Westbrook GL. miR-132 mediates the integration of newborn neurons into the adult dentate gyrus. Plos One. 6: e19077. PMID 21611182 DOI: 10.1371/Journal.Pone.0019077 |
0.713 |
|
| 2011 |
Blaiss CA, Yu TS, Zhang G, Chen J, Dimchev G, Parada LF, Powell CM, Kernie SG. Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4906-16. PMID 21451029 DOI: 10.1523/Jneurosci.5265-10.2011 |
0.484 |
|
| 2011 |
Harada C, Guo X, Namekata K, Kimura A, Nakamura K, Tanaka K, Parada LF, Harada T. Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration. Nature Communications. 2: 189. PMID 21304518 DOI: 10.1038/ncomms1190 |
0.306 |
|
| 2009 |
Choi SH, Li Y, Parada LF, Sisodia SS. Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF. Molecular Neurodegeneration. 4: 52. PMID 20025751 DOI: 10.1186/1750-1326-4-52 |
0.415 |
|
| 2009 |
Lauchle JO, Kim D, Le DT, Akagi K, Crone M, Krisman K, Warner K, Bonifas JM, Li Q, Coakley KM, Diaz-Flores E, Gorman M, Przybranowski S, Tran M, Kogan SC, ... ... Parada L, et al. Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature. 461: 411-4. PMID 19727076 DOI: 10.1038/Nature08279 |
0.332 |
|
| 2009 |
Zhou J, Blundell J, Ogawa S, Kwon CH, Zhang W, Sinton C, Powell CM, Parada LF. Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1773-83. PMID 19211884 DOI: 10.1523/JNEUROSCI.5685-08.2009 |
0.57 |
|
| 2009 |
Chen J, Kwon CH, Lin L, Li Y, Parada LF. Inducible site-specific recombination in neural stem/progenitor cells. Genesis (New York, N.Y. : 2000). 47: 122-31. PMID 19117051 DOI: 10.1002/Dvg.20465 |
0.354 |
|
| 2009 |
Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell. 15: 45-56. PMID 19111880 DOI: 10.1016/J.Ccr.2008.12.006 |
0.347 |
|
| 2008 |
Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron. 59: 399-412. PMID 18701066 DOI: 10.1016/J.Neuron.2008.06.023 |
0.703 |
|
| 2008 |
Luikart BW, Zhang W, Wayman GA, Kwon CH, Westbrook GL, Parada LF. Neurotrophin-dependent dendritic filopodial motility: a convergence on PI3K signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7006-12. PMID 18596174 DOI: 10.1523/Jneurosci.0195-08.2008 |
0.73 |
|
| 2008 |
Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF. Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Research. 68: 3286-94. PMID 18451155 DOI: 10.1158/0008-5472.Can-07-6867 |
0.332 |
|
| 2008 |
Lush ME, Li Y, Kwon CH, Chen J, Parada LF. Neurofibromin is required for barrel formation in the mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1580-7. PMID 18272679 DOI: 10.1523/Jneurosci.5236-07.2008 |
0.374 |
|
| 2008 |
Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment (DOI:10.1016/j.neuron.2008.06.023) Neuron. 60: 730. DOI: 10.1016/J.Neuron.2008.10.021 |
0.677 |
|
| 2007 |
Romero MI, Lin L, Lush ME, Lei L, Parada LF, Zhu Y. Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2124-34. PMID 17314307 DOI: 10.1523/JNEUROSCI.4363-06.2007 |
0.324 |
|
| 2007 |
Monteggia LM, Luikart B, Barrot M, Theobold D, Malkovska I, Nef S, Parada LF, Nestler EJ. Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biological Psychiatry. 61: 187-97. PMID 16697351 DOI: 10.1016/J.Biopsych.2006.03.021 |
0.643 |
|
| 2007 |
Yang F, Ingram D, Chen S, Robertson K, Li X, Yuan J, Knoll S, Horn W, Hutchins G, Parada L, Clapp DW. Imatinib Mesylate Reduces Plexiform Neurofibromas by Targeting the Hematopoietic Microenvironment. Blood. 110: 1915-1915. DOI: 10.1182/Blood.V110.11.1915.1915 |
0.345 |
|
| 2006 |
Luikart BW, Parada LF. Receptor tyrosine kinase B-mediated excitatory synaptogenesis. Progress in Brain Research. 157: 15-24. PMID 17167900 DOI: 10.1016/S0079-6123(06)57002-5 |
0.67 |
|
| 2006 |
Tran PV, Akana SF, Malkovska I, Dallman MF, Parada LF, Ingraham HA. Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF-1 gene dosage. The Journal of Comparative Neurology. 498: 637-48. PMID 16917842 DOI: 10.1002/Cne.21070 |
0.302 |
|
| 2006 |
Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, Li Y, Baker SJ, Parada LF. Pten regulates neuronal arborization and social interaction in mice. Neuron. 50: 377-88. PMID 16675393 DOI: 10.1016/J.Neuron.2006.03.023 |
0.739 |
|
| 2006 |
Kwon CH, Zhou J, Li Y, Kim KW, Hensley LL, Baker SJ, Parada LF. Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis (New York, N.Y. : 2000). 44: 130-5. PMID 16496331 DOI: 10.1002/Gene.20197 |
0.359 |
|
| 2006 |
Yang F, Ingram DA, Chen S, Yuan J, Li X, Horn W, Parada L, Clapp DW. Mast Cells Are Integral Components of the Tumor Microenvironment That Are Required for Plexiform Neurofibroma Progression. Blood. 108: 677-677. DOI: 10.1182/Blood.V108.11.677.677 |
0.338 |
|
| 2005 |
Lei L, Laub F, Lush M, Romero M, Zhou J, Luikart B, Klesse L, Ramirez F, Parada LF. The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons. Genes & Development. 19: 1354-64. PMID 15937222 DOI: 10.1101/Gad.1227705 |
0.681 |
|
| 2005 |
Luikart BW, Nef S, Virmani T, Lush ME, Liu Y, Kavalali ET, Parada LF. TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3774-86. PMID 15829629 DOI: 10.1523/Jneurosci.0041-05.2005 |
0.649 |
|
| 2005 |
Lauchle JO, Le D, Kim D, Tran M, Peterson A, Przybranowski S, Parada L, Wolff L, Leopold J, Shannon KM. Disease Stage Strongly Modulates Responsiveness to Targeted Agents in Nf1 Mutant Mice with Myeloprolfierative Disease (MPD) and Acute Myeloid Leukemia (AML). Blood. 106: 496-496. DOI: 10.1182/Blood.V106.11.496.496 |
0.343 |
|
| 2004 |
He XP, Kotloski R, Nef S, Luikart BW, Parada LF, McNamara JO. Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. Neuron. 43: 31-42. PMID 15233915 DOI: 10.1016/J.Neuron.2004.06.019 |
0.665 |
|
| 2004 |
Le DT, Kong N, Zhu Y, Lauchle JO, Aiyigari A, Braun BS, Wang E, Kogan SC, Le Beau MM, Parada L, Shannon KM. Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder. Blood. 103: 4243-50. PMID 14982883 DOI: 10.1182/Blood-2003-08-2650 |
0.367 |
|
| 2003 |
Luikart BW, Nef S, Shipman T, Parada LF. In vivo role of truncated trkb receptors during sensory ganglion neurogenesis. Neuroscience. 117: 847-58. PMID 12654337 DOI: 10.1016/S0306-4522(02)00719-4 |
0.676 |
|
| 2002 |
Kelly-Spratt KS, Klesse LJ, Parada LF. BDNF activated TrkB/IRR receptor chimera promotes survival of sympathetic neurons through Ras and PI-3 kinase signaling. Journal of Neuroscience Research. 69: 151-9. PMID 12111796 DOI: 10.1002/jnr.10172 |
0.305 |
|
| 2000 |
Liebl DJ, Klesse LJ, Tessarollo L, Wohlman T, Parada LF. Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 97: 2297-302. PMID 10681461 DOI: 10.1073/pnas.040562597 |
0.318 |
|
| 1999 |
Liebl DJ, Mbiene JP, Parada LF. NT4/5 mutant mice have deficiency in gustatory papillae and taste bud formation. Developmental Biology. 213: 378-89. PMID 10479455 DOI: 10.1006/dbio.1999.9385 |
0.319 |
|
| 1999 |
Kahn MA, Kumar S, Liebl D, Chang R, Parada LF, De Vellis J. Mice lacking NT-3, and its receptor TrkC, exhibit profound deficiencies in CNS glial cells. Glia. 26: 153-65. PMID 10384880 DOI: 10.1002/(Sici)1098-1136(199904)26:2<153::Aid-Glia6>3.0.Co;2-Z |
0.327 |
|
| 1998 |
Klesse LJ, Parada LF. p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10420-8. PMID 9852579 |
0.303 |
|
| 1997 |
Liebl DJ, Tessarollo L, Palko ME, Parada LF. Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9113-21. PMID 9364058 |
0.326 |
|
| 1995 |
Vogel KS, Brannan CI, Jenkins NA, Copeland NG, Parada LF. Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons. Cell. 82: 733-42. PMID 7671302 DOI: 10.1016/0092-8674(95)90470-0 |
0.325 |
|
| 1994 |
Tessarollo L, Vogel KS, Palko ME, Reid SW, Parada LF. Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 11844-8. PMID 7991545 |
0.305 |
|
| 1992 |
Holtzman DM, Li Y, Parada LF, Kinsman S, Chen CK, Valletta JS, Zhou J, Long JB, Mobley WC. p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF. Neuron. 9: 465-78. PMID 1524827 DOI: 10.1016/0896-6273(92)90184-F |
0.365 |
|
| 1986 |
Land H, Chen AC, Morgenstern JP, Parada LF, Weinberg RA. Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts. Molecular and Cellular Biology. 6: 1917-25. PMID 3785184 DOI: 10.1128/Mcb.6.6.1917 |
0.423 |
|
| 1985 |
Dotto GP, Parada LF, Weinberg RA. Specific growth response of ras-transformed embryo fibroblasts to tumour promoters. Nature. 318: 472-5. PMID 4069218 DOI: 10.1038/318472A0 |
0.443 |
|
| 1985 |
Parada LF, Land H, Chen A, Morganstern J, Weinberg RA. Cooperation between cellular oncogenes in the transformation of primary rat embryo fibroblasts. Progress in Medical Virology. Fortschritte Der Medizinischen Virusforschung. Progrã¨S En Virologie Mã©Dicale. 32: 115-28. PMID 4023262 |
0.363 |
|
| 1984 |
Parada LF, Land H, Weinberg RA, Wolf D, Rotter V. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature. 312: 649-51. PMID 6390217 DOI: 10.1038/312649A0 |
0.421 |
|
| 1984 |
Lenoir GM, Land H, Parada LF, Cunningham JM, Weinberg RA. Activated oncogenes in Burkitt's lymphoma. Current Topics in Microbiology and Immunology. 113: 6-14. PMID 6090072 DOI: 10.1007/978-3-642-69860-6_2 |
0.404 |
|
| 1983 |
Murray MJ, Cunningham JM, Parada LF, Dautry F, Lebowitz P, Weinberg RA. The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell. 33: 749-57. PMID 6683594 DOI: 10.1016/0092-8674(83)90017-X |
0.444 |
|
| 1983 |
Parada LF, Shih C, Murray M, Weinberg RA. The oncogene of a human bladder carcinoma. Progress in Nucleic Acid Research and Molecular Biology. 29: 269-72. PMID 6665172 DOI: 10.1016/S0079-6603(08)60458-4 |
0.388 |
|
| 1983 |
Land H, Parada LF, Weinberg RA. Cellular oncogenes and multistep carcinogenesis. Science (New York, N.Y.). 222: 771-8. PMID 6356358 DOI: 10.1126/Science.6356358 |
0.44 |
|
| 1983 |
Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 304: 596-602. PMID 6308472 DOI: 10.1038/304596A0 |
0.412 |
|
| 1983 |
Parada LF, Weinberg RA. Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene. Molecular and Cellular Biology. 3: 2298-301. PMID 6197628 |
0.422 |
|
| 1982 |
Parada LF, Tabin CJ, Shih C, Weinberg RA. Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene. Nature. 297: 474-8. PMID 6283357 DOI: 10.1038/297474A0 |
0.567 |
|
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