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Bakul S. Bhatnagar, Ph.D. - Publications

Affiliations: 
2006 University of Connecticut, Storrs, CT, United States 
Area:
Pharmaceutical Chemistry, Pharmacology
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sebastião IB, Bhatnagar B, Tchessalov S. A Kinetic Model for Spray-Freezing of Pharmaceuticals. Journal of Pharmaceutical Sciences. PMID 33278411 DOI: 10.1016/j.xphs.2020.11.032  0.319
2020 Sane P, Bogner RH, Bhatnagar B, Tchessalov S. Reconstitution of Highly-Concentrated Lyophilized Proteins: Part 1 Amorphous Formulations. Journal of Pharmaceutical Sciences. PMID 32070705 DOI: 10.1016/J.Xphs.2020.02.006  0.605
2020 Bhatnagar BS, Sonje J, Shalaev E, Martin SWH, Teagarden DL, Suryanarayanan R. A refined phase diagram of the tert-butanol-water system and implications on lyophilization process optimization of pharmaceuticals. Physical Chemistry Chemical Physics : Pccp. PMID 31894786 DOI: 10.1039/C9Cp06576H  0.383
2019 Bhatnagar B, Zakharov B, Fisyuk A, Wen X, Karim F, Lee K, Seryotkin Y, Mogodi M, Fitch A, Boldyreva E, Kostyuchenko A, Shalaev E. Protein/Ice Interaction: High-Resolution Synchrotron X-ray Diffraction Differentiates Pharmaceutical Proteins from Lysozyme. The Journal of Physical Chemistry. B. PMID 31260313 DOI: 10.1021/Acs.Jpcb.9B02443  0.421
2019 Sebastião IB, Bhatnagar B, Tchessalov S, Ohtake S, Plitzko M, Luy B, Alexeenko A. Bulk Dynamic Spray Freeze-Drying Part 2: Model-Based Parametric Study for sssssSpray-Freezing Process Characterization. Journal of Pharmaceutical Sciences. PMID 30682340 DOI: 10.1016/J.Xphs.2019.01.011  0.378
2019 Sebastião IB, Bhatnagar B, Tchessalov S, Ohtake S, Plitzko M, Luy B, Alexeenko A. Bulk Dynamic Spray Freeze-Drying Part 1: Modeling of Droplet Cooling and Phase Change. Journal of Pharmaceutical Sciences. PMID 30677417 DOI: 10.1016/J.Xphs.2019.01.009  0.385
2018 Huang M, Childs E, Roffi K, Karim F, Juneau J, Bhatnagar B, Tchessalov S. Investigation of fogging behavior in a lyophilized drug product. Journal of Pharmaceutical Sciences. PMID 30339866 DOI: 10.1016/J.Xphs.2018.10.015  0.311
2014 Walters RH, Bhatnagar B, Tchessalov S, Izutsu K, Tsumoto K, Ohtake S. Next generation drying technologies for pharmaceutical applications. Journal of Pharmaceutical Sciences. 103: 2673-95. PMID 24916125 DOI: 10.1002/Jps.23998  0.314
2011 Bhatnagar BS, Martin SW, Hodge TS, Das TK, Joseph L, Teagarden DL, Shalaev EY, Suryanarayanan R. Investigation of PEG crystallization in frozen and freeze-dried PEGylated recombinant human growth hormone-sucrose systems: implications on storage stability. Journal of Pharmaceutical Sciences. 100: 3062-75. PMID 21491456 DOI: 10.1002/Jps.22562  0.409
2010 Bhatnagar BS, Martin SM, Teagarden DL, Shalaev EY, Suryanarayanan R. Investigation of PEG crystallization in frozen PEG-sucrose-water solutions: II. Characterization of the equilibrium behavior during freeze-thawing. Journal of Pharmaceutical Sciences. 99: 4510-24. PMID 20845450 DOI: 10.1002/Jps.22182  0.49
2010 Bhatnagar BS, Martin SM, Teagarden DL, Shalaev EY, Suryanarayanan R. Investigation of PEG crystallization in frozen PEG-sucrose-water solutions. I. Characterization of the nonequilibrium behavior during freeze-thawing. Journal of Pharmaceutical Sciences. 99: 2609-19. PMID 20091827 DOI: 10.1002/jps.22040  0.316
2008 Bhatnagar BS, Pikal MJ, Bogner RH. Study of the individual contributions of ice formation and freeze-concentration on isothermal stability of lactate dehydrogenase during freezing. Journal of Pharmaceutical Sciences. 97: 798-814. PMID 17506511 DOI: 10.1002/Jps.21017  0.61
2007 Bhatnagar BS, Bogner RH, Pikal MJ. Protein stability during freezing: separation of stresses and mechanisms of protein stabilization. Pharmaceutical Development and Technology. 12: 505-23. PMID 17963151 DOI: 10.1080/10837450701481157  0.586
2005 Bhatnagar BS, Nehm SJ, Pikal MJ, Bogner RH. Post-thaw aging affects activity of lactate dehydrogenase. Journal of Pharmaceutical Sciences. 94: 1382-8. PMID 15858849 DOI: 10.1002/Jps.20345  0.568
2005 Bhatnagar BS, Cardon S, Pikal MJ, Bogner RH. Reliable determination of freeze-concentration using DSC Thermochimica Acta. 425: 149-163. DOI: 10.1016/J.Tca.2004.06.017  0.573
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