Wen-jun Gao - Publications

Neurobiology and Anatomy Drexel University College of Medicine, Philadelphia, PA, United States 

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Xing B, Li YC, Gao WJ. GSK3β Hyperactivity during an Early Critical Period Impairs Prefrontal Synaptic Plasticity and Induces Lasting Deficits in Spine Morphology and Working Memory. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27353310 DOI: 10.1038/npp.2016.110  1
2016 Li YC, Yang SS, Gao WJ. Disruption of Akt signaling decreases dopamine sensitivity in modulation of inhibitory synaptic transmission in rat prefrontal cortex. Neuropharmacology. PMID 27163190 DOI: 10.1016/j.neuropharm.2016.05.002  1
2016 Xing B, Li YC, Gao WJ. Norepinephrine versus Dopamine and their Interaction in Modulating Synaptic Function in the Prefrontal Cortex. Brain Research. PMID 26790349 DOI: 10.1016/j.brainres.2016.01.005  1
2015 Li ML, Yang SS, Xing B, Ferguson BR, Gulchina Y, Li YC, Li F, Hu XQ, Gao WJ. LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment. Experimental Neurology. PMID 26341392 DOI: 10.1016/j.expneurol.2015.08.019  1
2015 Monaco SA, Gulchina Y, Gao WJ. NR2B subunit in the prefrontal cortex: A double-edged sword for working memory function and psychiatric disorders. Neuroscience and Biobehavioral Reviews. PMID 26143512 DOI: 10.1016/j.neubiorev.2015.06.022  1
2015 Li ML, Hu XQ, Li F, Gao WJ. Perspectives on the mGluR2/3 agonists as a therapeutic target for schizophrenia: Still promising or a dead end? Progress in Neuro-Psychopharmacology & Biological Psychiatry. 60: 66-76. PMID 25724760 DOI: 10.1016/j.pnpbp.2015.02.012  1
2015 Urban KR, Gao WJ. Evolution of the Study of Methylphenidate and Its Actions on the Adult Versus Juvenile Brain. Journal of Attention Disorders. 19: 603-19. PMID 22923783 DOI: 10.1177/1087054712455504  1
2014 Ferguson BR, Gao WJ. Development of thalamocortical connections between the mediodorsal thalamus and the prefrontal cortex and its implication in cognition. Frontiers in Human Neuroscience. 8: 1027. PMID 25620923 DOI: 10.3389/fnhum.2014.01027  1
2014 Chandler DJ, Waterhouse BD, Gao WJ. New perspectives on catecholaminergic regulation of executive circuits: evidence for independent modulation of prefrontal functions by midbrain dopaminergic and noradrenergic neurons. Frontiers in Neural Circuits. 8: 53. PMID 24904299 DOI: 10.3389/fncir.2014.00053  1
2014 Urban KR, Gao WJ. Performance enhancement at the cost of potential brain plasticity: neural ramifications of nootropic drugs in the healthy developing brain. Frontiers in Systems Neuroscience. 8: 38. PMID 24860437 DOI: 10.3389/fnsys.2014.00038  1
2014 Chandler DJ, Gao WJ, Waterhouse BD. Heterogeneous organization of the locus coeruleus projections to prefrontal and motor cortices. Proceedings of the National Academy of Sciences of the United States of America. 111: 6816-21. PMID 24753596 DOI: 10.1073/pnas.1320827111  1
2014 Pitcher J, Abt A, Myers J, Han R, Snyder M, Graziano A, Festa L, Kutzler M, Garcia F, Gao WJ, Fischer-Smith T, Rappaport J, Meucci O. Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction. The Journal of Clinical Investigation. 124: 656-69. PMID 24401274 DOI: 10.1172/JCI70090  1
2013 Urban KR, Gao WJ. Methylphenidate and the juvenile brain: enhancement of attention at the expense of cortical plasticity? Medical Hypotheses. 81: 988-94. PMID 24095262 DOI: 10.1016/j.mehy.2013.09.009  1
2013 Wang MJ, Li YC, Snyder MA, Wang H, Li F, Gao WJ. Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons. Plos One. 8: e61787. PMID 23593498 DOI: 10.1371/journal.pone.0061787  1
2013 Snyder MA, Gao WJ. NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia. Frontiers in Cellular Neuroscience. 7: 31. PMID 23543703 DOI: 10.3389/fncel.2013.00031  1
2013 Urban KR, Li YC, Gao WJ. Treatment with a clinically-relevant dose of methylphenidate alters NMDA receptor composition and synaptic plasticity in the juvenile rat prefrontal cortex. Neurobiology of Learning and Memory. 101: 65-74. PMID 23333502 DOI: 10.1016/j.nlm.2013.01.004  1
2013 Snyder MA, Adelman AE, Gao WJ. Gestational methylazoxymethanol exposure leads to NMDAR dysfunction in hippocampus during early development and lasting deficits in learning. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 328-40. PMID 22968815 DOI: 10.1038/npp.2012.180  1
2013 Li YC, Gao WJ. Corrigendum to GSK-3β activity and hyperdopamine-dependent behaviors [Neurosci. Biobehav. Rev. 35(January (3)) (2011) 645-654] Neuroscience and Biobehavioral Reviews. 37: 549. DOI: 10.1016/j.neubiorev.2013.01.023  1
2013 Li YC, Wang MJ, Gao WJ. Hyperdopaminergic Modulation of Inhibitory Transmission is Dependent on GSK-3β Signaling-Mediated Trafficking of GABAA Receptors Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 100-101. DOI: 10.1016/B978-0-12-800044-1.00087-8  1
2012 Li YC, Wang MJ, Gao WJ. Hyperdopaminergic modulation of inhibitory transmission is dependent on GSK-3β signaling-mediated trafficking of GABAA receptors. Journal of Neurochemistry. 122: 308-20. PMID 22676038 DOI: 10.1111/j.1471-4159.2012.07790.x  1
2012 Urban KR, Waterhouse BD, Gao WJ. Distinct age-dependent effects of methylphenidate on developing and adult prefrontal neurons. Biological Psychiatry. 72: 880-8. PMID 22609367 DOI: 10.1016/j.biopsych.2012.04.018  1
2012 Wang HX, Gao WJ. Prolonged exposure to NMDAR antagonist induces cell-type specific changes of glutamatergic receptors in rat prefrontal cortex. Neuropharmacology. 62: 1808-22. PMID 22182778 DOI: 10.1016/j.neuropharm.2011.11.024  1
2011 Agster KL, Clark BD, Gao WJ, Shumsky JS, Wang HX, Berridge CW, Waterhouse BD. Experimental strategies for investigating psychostimulant drug actions and prefrontal cortical function in ADHD and related attention disorders. Anatomical Record (Hoboken, N.J. : 2007). 294: 1698-712. PMID 21901844 DOI: 10.1002/ar.21403  1
2011 Li YC, Kellendonk C, Simpson EH, Kandel ER, Gao WJ. D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 108: 12107-12. PMID 21730148 DOI: 10.1073/pnas.1109718108  1
2011 Xi D, Li YC, Snyder MA, Gao RY, Adelman AE, Zhang W, Shumsky JS, Gao WJ. Group II metabotropic glutamate receptor agonist ameliorates MK801-induced dysfunction of NMDA receptors via the Akt/GSK-3β pathway in adult rat prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1260-74. PMID 21326193 DOI: 10.1038/npp.2011.12  1
2011 Li YC, Gao WJ. GSK-3β activity and hyperdopamine-dependent behaviors. Neuroscience and Biobehavioral Reviews. 35: 645-54. PMID 20727368 DOI: 10.1016/j.neubiorev.2010.08.001  1
2010 Wang LD, Zhou FY, Li XM, Sun LD, Song X, Jin Y, Li JM, Kong GQ, Qi H, Cui J, Zhang LQ, Yang JZ, Li JL, Li XC, Ren JL, ... ... Gao WJ, et al. Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nature Genetics. 42: 759-63. PMID 20729853 DOI: 10.1038/ng.648  0.6
2010 Hu JL, Liu G, Li YC, Gao WJ, Huang YQ. Dopamine D1 receptor-mediated NMDA receptor insertion depends on Fyn but not Src kinase pathway in prefrontal cortical neurons. Molecular Brain. 3: 20. PMID 20569495 DOI: 10.1186/1756-6606-3-20  1
2010 Wang HX, Gao WJ. Development of calcium-permeable AMPA receptors and their correlation with NMDA receptors in fast-spiking interneurons of rat prefrontal cortex. The Journal of Physiology. 588: 2823-38. PMID 20547673 DOI: 10.1113/jphysiol.2010.187591  1
2010 Li YC, Liu G, Hu JL, Gao WJ, Huang YQ. Dopamine D(1) receptor-mediated enhancement of NMDA receptor trafficking requires rapid PKC-dependent synaptic insertion in the prefrontal neurons. Journal of Neurochemistry. 114: 62-73. PMID 20374423 DOI: 10.1111/j.1471-4159.2010.06720.x  1
2009 Li YC, Xi D, Roman J, Huang YQ, Gao WJ. Activation of glycogen synthase kinase-3 beta is required for hyperdopamine and D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15551-63. PMID 20007479 DOI: 10.1523/JNEUROSCI.3336-09.2009  1
2009 Ji Y, Yang F, Papaleo F, Wang HX, Gao WJ, Weinberger DR, Lu B. Role of dysbindin in dopamine receptor trafficking and cortical GABA function. Proceedings of the National Academy of Sciences of the United States of America. 106: 19593-8. PMID 19887632 DOI: 10.1073/pnas.0904289106  1
2009 Xi D, Zhang W, Wang HX, Stradtman GG, Gao WJ. Dizocilpine (MK-801) induces distinct changes of N-methyl-D-aspartic acid receptor subunits in parvalbumin-containing interneurons in young adult rat prefrontal cortex. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 1395-408. PMID 19435549 DOI: 10.1017/S146114570900042X  1
2009 Wang HX, Gao WJ. Cell type-specific development of NMDA receptors in the interneurons of rat prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2028-40. PMID 19242405 DOI: 10.1038/npp.2009.20  1
2009 Xi D, Keeler B, Zhang W, Houle JD, Gao WJ. NMDA receptor subunit expression in GABAergic interneurons in the prefrontal cortex: application of laser microdissection technique. Journal of Neuroscience Methods. 176: 172-81. PMID 18845188 DOI: 10.1016/j.jneumeth.2008.09.013  1
2008 Wang H, Stradtman GG, Wang XJ, Gao WJ. A specialized NMDA receptor function in layer 5 recurrent microcircuitry of the adult rat prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 105: 16791-6. PMID 18922773 DOI: 10.1073/pnas.0804318105  1
2007 Gao WJ. Acute clozapine suppresses synchronized pyramidal synaptic network activity by increasing inhibition in the ferret prefrontal cortex. Journal of Neurophysiology. 97: 1196-208. PMID 17182915 DOI: 10.1152/jn.00400.2006  1
2006 Gao WJ, Goldman-Rakic PS. NMDA receptor-mediated epileptiform persistent activity requires calcium release from intracellular stores in prefrontal neurons. Experimental Neurology. 197: 495-504. PMID 16289054 DOI: 10.1016/j.expneurol.2005.05.018  1
2004 Gao WJ, Zheng ZH. Target-specific differences in somatodendritic morphology of layer V pyramidal neurons in rat motor cortex. The Journal of Comparative Neurology. 476: 174-85. PMID 15248197 DOI: 10.1002/cne.20224  1
2003 Gao WJ, Wang Y, Goldman-Rakic PS. Dopamine modulation of perisomatic and peridendritic inhibition in prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1622-30. PMID 12629166 DOI: 10.1523/JNEUROSCI.23-05-01622.2003  1
2003 Gao WJ, Goldman-Rakic PS. Selective modulation of excitatory and inhibitory microcircuits by dopamine. Proceedings of the National Academy of Sciences of the United States of America. 100: 2836-41. PMID 12591942 DOI: 10.1073/pnas.262796399  1
2003 Gao W, Goldman-Rakic P. Target cell-specific modulation of excitatory synaptic transmission by dopamine in the prefrontal cortex Schizophrenia Research. 60: 106. DOI: 10.1016/S0920-9964(03)80842-3  1
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