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Todd Macfarlan, Ph.D. - Publications

Affiliations: 
2005 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Du C, Jiang J, Li Y, Yu M, Jin J, Chen S, Fan H, Macfarlan TS, Cao B, Sun MA. Regulation of endogenous retrovirus-derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells. Genome Research. PMID 36806146 DOI: 10.1101/gr.277150.122  0.344
2021 Agarwal S, Bonefas KM, Garay PM, Brookes E, Murata-Nakamura Y, Porter RS, Macfarlan TS, Ren B, Iwase S. KDM1A maintains genome-wide homeostasis of transcriptional enhancers. Genome Research. PMID 33414108 DOI: 10.1101/gr.234559.118  0.437
2020 Bertozzi TM, Elmer JL, Macfarlan TS, Ferguson-Smith AC. KRAB zinc finger protein diversification drives mammalian interindividual methylation variability. Proceedings of the National Academy of Sciences of the United States of America. 117: 31290-31300. PMID 33239447 DOI: 10.1073/pnas.2017053117  0.369
2020 Kumar J, Kaur G, Ren R, Lu Y, Lin K, Li J, Huang Y, Patel A, Barton MC, Macfarlan T, Zhang X, Cheng X. KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells. Nar Cancer. 2: zcaa007. PMID 32743551 DOI: 10.1093/narcan/zcaa007  0.382
2020 Mahgoub M, Paiano J, Bruno M, Wu W, Pathuri S, Zhang X, Ralls S, Cheng X, Nussenzweig A, Macfarlan TS. Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice. Elife. 9. PMID 32352380 DOI: 10.7554/Elife.53360  0.43
2020 Chen C, Sun MA, Warzecha C, Bachu M, Dey A, Wu T, Adams PD, Macfarlan T, Love P, Ozato K. HIRA, a DiGeorge Syndrome Candidate Gene, Confers Proper Chromatin Accessibility on HSCs and Supports All Stages of Hematopoiesis. Cell Reports. PMID 32075733 DOI: 10.1016/J.Celrep.2020.01.062  0.463
2020 Yang F, Huang X, Zang R, Chen J, Fidalgo M, Sanchez-Priego C, Yang J, Caichen A, Ma F, Macfarlan T, Wang H, Gao S, Zhou H, Wang J. DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State. Cell Stem Cell. 26: 234-250.e7. PMID 32032525 DOI: 10.1016/J.Stem.2020.01.004  0.303
2019 Seah MKY, Wang Y, Goy PV, Loh HM, Peh WJ, Loh DHP, Han BY, Wong E, Leong EL, Wolf G, Mzoughi S, Wollmann H, Macfarlan TS, Guccione E, Messerschmidt DM. The KRAB-Zinc finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons. Development (Cambridge, England). PMID 30846446 DOI: 10.1242/dev.170266  0.408
2018 Patel A, Yang P, Tinkham M, Pradhan M, Sun MA, Wang Y, Hoang D, Wolf G, Horton JR, Zhang X, Macfarlan T, Cheng X. DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins. Cell. PMID 29551271 DOI: 10.1016/J.Cell.2018.02.058  0.391
2017 Yang P, Wang Y, Macfarlan TS. The Role of KRAB-ZFPs in Transposable Element Repression and Mammalian Evolution. Trends in Genetics : Tig. PMID 28935117 DOI: 10.1016/J.Tig.2017.08.006  0.404
2016 Wang C, Lee JE, Lai B, Macfarlan TS, Xu S, Zhuang L, Liu C, Peng W, Ge K. Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition. Proceedings of the National Academy of Sciences of the United States of America. PMID 27698142 DOI: 10.1073/Pnas.1606857113  0.331
2016 Thompson PJ, Macfarlan TS, Lorincz MC. Long Terminal Repeats: From Parasitic Elements to Building Blocks of the Transcriptional Regulatory Repertoire. Molecular Cell. 62: 766-776. PMID 27259207 DOI: 10.1016/j.molcel.2016.03.029  0.331
2015 Geeven G, Zhu Y, Kim BJ, Bartholdy BA, Yang SM, Macfarlan TS, Gifford WD, Pfaff SL, Verstegen MJ, Pinto H, Vermunt MW, Creyghton MP, Wijchers PJ, Stamatoyannopoulos JA, Skoultchi AI, et al. Local compartment changes and regulatory landscape alterations in histone H1-depleted cells. Genome Biology. 16: 289. PMID 26700097 DOI: 10.1186/S13059-015-0857-0  0.537
2015 Wolf G, Yang P, Füchtbauer AC, Füchtbauer EM, Silva AM, Park C, Wu W, Nielsen AL, Pedersen FS, Macfarlan TS. The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses. Genes & Development. 29: 538-54. PMID 25737282 DOI: 10.1101/Gad.252767.114  0.491
2015 Yang P, Wu W, Macfarlan TS. Maternal histone variants and their chaperones promote paternal genome activation and boost somatic cell reprogramming. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 52-9. PMID 25328107 DOI: 10.1002/Bies.201400072  0.492
2013 Rowe HM, Kapopoulou A, Corsinotti A, Fasching L, Macfarlan TS, Tarabay Y, Viville S, Jakobsson J, Pfaff SL, Trono D. TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells. Genome Research. 23: 452-61. PMID 23233547 DOI: 10.1101/Gr.147678.112  0.427
2011 Macfarlan TS, Gifford WD, Agarwal S, Driscoll S, Lettieri K, Wang J, Andrews SE, Franco L, Rosenfeld MG, Ren B, Pfaff SL. Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A. Genes & Development. 25: 594-607. PMID 21357675 DOI: 10.1101/Gad.2008511  0.338
2009 Loomis RJ, Naoe Y, Parker JB, Savic V, Bozovsky MR, Macfarlan T, Manley JL, Chakravarti D. Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation. Molecular Cell. 33: 450-61. PMID 19250906 DOI: 10.1016/J.Molcel.2009.02.003  0.774
2006 Macfarlan T, Parker JB, Nagata K, Chakravarti D. Thanatos-associated protein 7 associates with template activating factor-Ibeta and inhibits histone acetylation to repress transcription. Molecular Endocrinology (Baltimore, Md.). 20: 335-47. PMID 16195249 DOI: 10.1210/Me.2005-0248  0.814
2005 Macfarlan T, Kutney S, Altman B, Montross R, Yu J, Chakravarti D. Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor. The Journal of Biological Chemistry. 280: 7346-58. PMID 15561719 DOI: 10.1074/Jbc.M411675200  0.687
2004 Hong R, Macfarlan T, Kutney SN, Seo SB, Mukai Y, Yelin F, Pasternack GR, Chakravarti D. The identification of phosphorylation sites of pp32 and biochemical purification of a cellular pp32-kinase. Biochemistry. 43: 10157-65. PMID 15287743 DOI: 10.1021/Bi0493968  0.63
2004 Kutney SN, Hong R, Macfarlan T, Chakravarti D. A signaling role of histone-binding proteins and INHAT subunits pp32 and Set/TAF-Ibeta in integrating chromatin hypoacetylation and transcriptional repression. The Journal of Biological Chemistry. 279: 30850-5. PMID 15136563 DOI: 10.1074/Jbc.M404969200  0.689
2002 Li F, Macfarlan T, Pittman RN, Chakravarti D. Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities. The Journal of Biological Chemistry. 277: 45004-12. PMID 12297501 DOI: 10.1074/Jbc.M205259200  0.784
2002 Seo SB, Macfarlan T, McNamara P, Hong R, Mukai Y, Heo S, Chakravarti D. Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex. The Journal of Biological Chemistry. 277: 14005-10. PMID 11830591 DOI: 10.1074/Jbc.M112455200  0.813
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