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Yanfang Xian, Ph.D. - Publications

Affiliations: 
2013 The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Neuroscience Biology, Pharmacology, Cell Biology, Molecular Biology
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yang W, Liu Y, Xu QQ, Xian YF, Lin ZX. Sulforaphene Ameliorates Neuroinflammation and Hyperphosphorylated Tau Protein via Regulating the PI3K/Akt/GSK-3 Pathway in Experimental Models of Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2020: 4754195. PMID 32963694 DOI: 10.1155/2020/4754195  0.407
2020 Yuan Q, Xian YF, Huang YF, Wu W, Song YQ, Lin ZX. Intracisternal injection of beta-amyloid seeds promotes cerebral amyloid angiopathy. Brain, Behavior, and Immunity. PMID 32739364 DOI: 10.1016/J.Bbi.2020.07.038  0.348
2020 Xian YF, Qu C, Liu Y, Ip SP, Yuan QJ, Yang W, Lin ZX. Magnolol Ameliorates Behavioral Impairments and Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2020: 5920476. PMID 32714487 DOI: 10.1155/2020/5920476  0.4
2020 Zhao J, Lan X, Liu Y, Liu Y, Xian Y, Lin Z, Xu F. Anti-aging role of Chinese herbel medicine: an overview of scientific evidence from 2008 to 2018. Annals of Palliative Medicine. PMID 32389009 DOI: 10.21037/Apm.2020.04.09  0.322
2020 Chen L, Pan H, Bai Y, Li H, Yang W, Lin ZX, Cui W, Xian YF. Gelsemine, a natural alkaloid extracted from Gelsemium elegans Benth. alleviates neuroinflammation and cognitive impairments in Aβ oligomer-treated mice. Psychopharmacology. PMID 32363440 DOI: 10.1007/S00213-020-05522-Y  0.357
2020 Hu S, Xian Y, Fan Y, Mak S, Wang J, Tang J, Pang Y, Pi R, Tsim KW, Liu F, Lin Z, Han Y. Significant combination of Aβ aggregation inhibitory and neuroprotective properties in silico, in vitro and in vivo by bis(propyl)-cognitin, a multifunctional anti-Alzheimer's agent. European Journal of Pharmacology. 173065. PMID 32171792 DOI: 10.1016/J.Ejphar.2020.173065  0.359
2019 Li C, Ai G, Wang Y, Lu Q, Luo C, Tan L, Lin G, Liu Y, Li Y, Zeng H, Chen J, Lin Z, Xian Y, Huang X, Xie J, et al. Oxyberberine, a novel gut microbiota-mediated metabolite of berberine, possesses superior anti-colitis effect: impact on intestinal epithelial barrier, gut microbiota profile and TLR4-MyD88-NF-κB pathway. Pharmacological Research. 104603. PMID 31863867 DOI: 10.1016/J.Phrs.2019.104603  0.383
2019 Chen Y, Xian YF, Loo S, Lai Z, Chan WY, Liu L, Lin ZX. Huang-Lian-Jie-Du extract ameliorates atopic dermatitis-like skin lesions induced by 2,4-dinitrobenzene in mice via suppression of MAPKs and NF-κB pathways. Journal of Ethnopharmacology. 112367. PMID 31678637 DOI: 10.1016/J.Jep.2019.112367  0.342
2019 Xie JH, Lai ZQ, Zheng XH, Xian YF, Li Q, Ip SP, Xie YL, Chen JN, Su ZR, Lin ZX, Yang XB. Apoptosis induced by bruceine D in human non‑small‑cell lung cancer cells involves mitochondrial ROS‑mediated death signaling. International Journal of Molecular Medicine. PMID 31638181 DOI: 10.3892/Ijmm.2019.4363  0.317
2019 Li HQ, Ip SP, Yuan QJ, Zheng GQ, Kw Tsim K, Tx Dong T, Lin G, Han Y, Liu Y, Xian YF, Lin ZX. Isorhynchophylline Ameliorates Cognitive Impairment via Modulating Amyloid Pathology, Tau Hyperphosphorylation and Neuroinflammation: Studies in a Transgenic Mouse Model of Alzheimer's Disease. Brain, Behavior, and Immunity. PMID 31476414 DOI: 10.1016/J.Bbi.2019.08.194  0.413
2019 Yang W, Ip SP, Liu L, Xian YF, Lin ZX. Uncaria rhynchophylla and Its Major Constituents on Central Nervous System: A Review on Their Pharmacological Actions. Current Vascular Pharmacology. PMID 31272356 DOI: 10.2174/1570161117666190704092841  0.302
2019 Xian YF, Ip SP, Li HQ, Qu C, Su ZR, Chen JN, Lin ZX. Isorhynchophylline exerts antidepressant-like effects in mice modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3β signaling pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802743RR. PMID 31233346 DOI: 10.1096/Fj.201802743Rr  0.4
2019 Zhang C, Wu X, Xian Y, Zhu L, Lin G, Lin ZX. Evidence on Integrating Pharmacokinetics to Find Truly Therapeutic Agent for Alzheimer's Disease: Comparative Pharmacokinetics and Disposition Kinetics Profiles of Stereoisomers Isorhynchophylline and Rhynchophylline in Rats. Evidence-Based Complementary and Alternative Medicine : Ecam. 2019: 4016323. PMID 30854007 DOI: 10.1155/2019/4016323  0.344
2018 Xian YF, Hu Z, Ip SP, Chen JN, Su ZR, Lai XP, Lin ZX. Comparison of the anti-inflammatory effects of Sinapis alba and Brassica juncea in mouse models of inflammation. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 50: 196-204. PMID 30466979 DOI: 10.1016/J.Phymed.2018.05.010  0.38
2018 Zhang ZB, Luo DD, Xie JH, Xian YF, Lai ZQ, Liu YH, Liu WH, Chen JN, Lai XP, Lin ZX, Su ZR. Curcumin's Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects Through Suppression of TAK1-NF-κB Pathway. Frontiers in Pharmacology. 9: 1181. PMID 30386242 DOI: 10.3389/Fphar.2018.01181  0.42
2018 Mo ZZ, Lin ZX, Su ZR, Zheng L, Li HL, Xie JH, Xian YF, Yi TG, Huang SQ, Chen JP. Angelica sinensis Supercritical Fluid CO Extract Attenuates D-Galactose-Induced Liver and Kidney Impairment in Mice by Suppressing Oxidative Stress and Inflammation. Journal of Medicinal Food. PMID 30109956 DOI: 10.1089/Jmf.2017.4061  0.363
2018 Chen HM, Lai ZQ, Liao HJ, Xie JH, Xian YF, Chen YL, Ip SP, Lin ZX, Su ZR. Synergistic antitumor effect of brusatol combined with cisplatin on colorectal cancer cells. International Journal of Molecular Medicine. PMID 29328398 DOI: 10.3892/Ijmm.2018.3372  0.316
2017 Lai ZQ, Ip SP, Liao HJ, Lu Z, Xie JH, Su ZR, Chen YL, Xian YF, Leung PS, Lin ZX. Brucein D, a Naturally Occurring Tetracyclic Triterpene Quassinoid, Induces Apoptosis in Pancreatic Cancer through ROS-Associated PI3K/Akt Signaling Pathway. Frontiers in Pharmacology. 8: 936. PMID 29311937 DOI: 10.3389/Fphar.2017.00936  0.369
2017 Huang YF, Zhou JT, Qu C, Dou YX, Huang QH, Lin ZX, Xian YF, Xie JH, Xie YL, Lai XP, Su ZR. Anti-inflammatory effects of Brucea javanica oil emulsion by suppressing NF-κB activation on dextran sulfate sodium-induced ulcerative colitis in mice. Journal of Ethnopharmacology. PMID 28119098 DOI: 10.1016/J.Jep.2017.01.042  0.372
2017 Mo Z, Liu Y, Li C, Xu L, Wen L, Xian Y, Lin Z, Zhan JY, Chen J, Xu F, Su ZR. Protective effect of SFE-CO2 of Ligusticum chuanxiong Hort against D-galactose induced injury in the mouse liver and kidney. Rejuvenation Research. PMID 28056664 DOI: 10.1089/Rej.2016.1870  0.332
2017 Yang W, Liu Y, Liang J, Lin Z, Kong Q, Xian Y, Guo D, Lai Z, Su Z, Huang X. β-Patchoulene, isolated from patchouli oil, suppresses inflammatory mediators in LPS-stimulated RAW264.7 macrophages: European Journal of Inflammation. 15: 136-141. DOI: 10.1177/1721727X17714694  0.333
2016 Xian YF, Fan D, Ip SP, Mao QQ, Lin ZX. Antidepressant-Like Effect of Isorhynchophylline in Mice. Neurochemical Research. PMID 27900600 DOI: 10.1007/S11064-016-2124-5  0.401
2016 Xian YF, Ip SP, Mao QQ, Lin ZX. Neuroprotective effects of honokiol against beta-amyloid-induced neurotoxicity via GSK-3β and β-catenin signaling pathway in PC12 cells. Neurochemistry International. PMID 27131736 DOI: 10.1016/J.Neuint.2016.04.014  0.377
2016 Xie J, Lin Z, Xian Y, Kong S, Lai Z, Ip S, Chen H, Guo H, Su Z, Yang X, Xu Y, Su Z. (-)-Patchouli alcohol protects against Helicobacter pylori urease-induced apoptosis, oxidative stress and inflammatory response in human gastric epithelial cells. International Immunopharmacology. 35: 43-52. PMID 27017292 DOI: 10.1016/J.Intimp.2016.02.022  0.373
2016 Chen Y, Xian Y, Lai Z, Loo S, Chan W, Lin ZX. Anti-inflammatory and anti-allergic effects and underlying mechanisms of Huang-Lian-Jie-Du Extract: Implication for atopic dermatitis treatment. Journal of Ethnopharmacology. PMID 26976763 DOI: 10.1016/J.Jep.2016.03.028  0.369
2014 Li YC, Xian YF, Su ZR, Ip SP, Xie JH, Liao JB, Wu DW, Li CW, Chen JN, Lin ZX, Lai XP. Pogostone suppresses proinflammatory mediator production and protects against endotoxic shock in mice. Journal of Ethnopharmacology. 157: 212-21. PMID 25256685 DOI: 10.1016/J.Jep.2014.09.023  0.375
2014 Feng XX, Yu XT, Li WJ, Kong SZ, Liu YH, Zhang X, Xian YF, Zhang XJ, Su ZR, Lin ZX. Effects of topical application of patchouli alcohol on the UV-induced skin photoaging in mice. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 63: 113-23. PMID 25033712 DOI: 10.1016/J.Ejps.2014.07.001  0.332
2014 Xian YF, Su ZR, Chen JN, Lai XP, Mao QQ, Cheng CH, Ip SP, Lin ZX. Isorhynchophylline improves learning and memory impairments induced by D-galactose in mice. Neurochemistry International. 76: 42-9. PMID 24984171 DOI: 10.1016/J.Neuint.2014.06.011  0.375
2014 Mao QQ, Huang Z, Zhong XM, Xian YF, Ip SP. Piperine reverses the effects of corticosterone on behavior and hippocampal BDNF expression in mice. Neurochemistry International. 74: 36-41. PMID 24816193 DOI: 10.1016/J.Neuint.2014.04.017  0.371
2014 Mao QQ, Huang Z, Zhong XM, Xian YF, Ip SP. Piperine reverses chronic unpredictable mild stress-induced behavioral and biochemical alterations in rats. Cellular and Molecular Neurobiology. 34: 403-8. PMID 24401942 DOI: 10.1007/S10571-014-0025-1  0.325
2014 Mao QQ, Huang Z, Zhong XM, Xian YF, Ip SP. Brain-derived neurotrophic factor signalling mediates the antidepressant-like effect of piperine in chronically stressed mice. Behavioural Brain Research. 261: 140-5. PMID 24361910 DOI: 10.1016/J.Bbr.2013.12.020  0.371
2014 Xian YF, Mao QQ, Wu JC, Su ZR, Chen JN, Lai XP, Ip SP, Lin ZX. Isorhynchophylline treatment improves the amyloid-β-induced cognitive impairment in rats via inhibition of neuronal apoptosis and tau protein hyperphosphorylation. Journal of Alzheimer's Disease : Jad. 39: 331-46. PMID 24164737 DOI: 10.3233/Jad-131457  0.389
2013 Xian YF, Lin ZX, Mao QQ, Chen JN, Su ZR, Lai XP, Ip PS. Isorhynchophylline Protects PC12 Cells Against Beta-Amyloid-Induced Apoptosis via PI3K/Akt Signaling Pathway. Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 163057. PMID 24319473 DOI: 10.1155/2013/163057  0.379
2013 Kong SZ, Xian YF, Ip SP, Lai XP, Shi XG, Lin ZX, Su ZR. Protective effects of hydroxysafflor yellow A on β-amyloid-induced neurotoxicity in PC12 cells. Neurochemical Research. 38: 951-60. PMID 23420419 DOI: 10.1007/S11064-013-1002-7  0.38
2013 Xian YF, Lin ZX, Ip SP, Su ZR, Chen JN, Lai XP. Comparison the neuropreotective effect of Cortex Phellodendri chinensis and Cortex Phellodendri amurensis against beta-amyloid-induced neurotoxicity in PC12 cells. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 20: 187-93. PMID 23123224 DOI: 10.1016/J.Phymed.2012.09.028  0.313
2012 Yang JM, Ip SP, Xian Y, Zhao M, Lin ZX, Yeung JH, Chan RC, Lee SS, Che CT. Impact of the herbal medicine Sophora flavescens on the oral pharmacokinetics of indinavir in rats: the involvement of CYP3A and P-glycoprotein. Plos One. 7: e31312. PMID 22359586 DOI: 10.1371/Journal.Pone.0031312  0.315
2011 Li YC, Xian YF, Ip SP, Su ZR, Su JY, He JJ, Xie QF, Lai XP, Lin ZX. Anti-inflammatory activity of patchouli alcohol isolated from Pogostemonis Herba in animal models. Fitoterapia. 82: 1295-301. PMID 21958968 DOI: 10.1016/J.Fitote.2011.09.003  0.391
2011 Xian YF, Mao QQ, Ip SP, Lin ZX, Che CT. Comparison on the anti-inflammatory effect of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis in 12-O-tetradecanoyl-phorbol-13-acetate-induced ear edema in mice. Journal of Ethnopharmacology. 137: 1425-30. PMID 21875660 DOI: 10.1016/J.Jep.2011.08.014  0.372
2011 Mao QQ, Xian YF, Ip SP, Che CT. Involvement of serotonergic system in the antidepressant-like effect of piperine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 1144-7. PMID 21477634 DOI: 10.1016/J.Pnpbp.2011.03.017  0.346
2011 Chen Y, Ip SP, Ko KM, Poon TC, Ng EW, Lai PB, Mao QQ, Xian YF, Che CT. A proteomic approach in investigating the hepatoprotective mechanism of Schisandrin B: role of raf kinase inhibitor protein. Journal of Proteome Research. 10: 299-304. PMID 21155602 DOI: 10.1021/Pr100871H  0.3
2011 Mao QQ, Xian YF, Ip SP, Tsai SH, Che CT. Protective effects of peony glycosides against corticosterone-induced cell death in PC12 cells through antioxidant action. Journal of Ethnopharmacology. 133: 1121-5. PMID 21111797 DOI: 10.1016/J.Jep.2010.11.043  0.357
2010 Mao QQ, Xian YF, Ip SP, Tsai SH, Che CT. Long-term treatment with peony glycosides reverses chronic unpredictable mild stress-induced depressive-like behavior via increasing expression of neurotrophins in rat brain. Behavioural Brain Research. 210: 171-7. PMID 20176057 DOI: 10.1016/J.Bbr.2010.02.026  0.345
2009 Mao QQ, Ip SP, Ko KM, Tsai SH, Xian YF, Che CT. Effects of peony glycosides on mice exposed to chronic unpredictable stress: further evidence for antidepressant-like activity. Journal of Ethnopharmacology. 124: 316-20. PMID 19375493 DOI: 10.1016/J.Jep.2009.04.019  0.329
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