David Howard Abbott - Publications

Affiliations: 
Wisconsin Regional Primate Research Center, Madison, WI, United States 
Area:
Behavioral Neuroendocrinology

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Zhou R, Bruns CM, Bird IM, Kemnitz JW, Dumesic DA, Abbott DH. Experimentally Induced Hyperinsulinemia Fails to Induce Polycystic Ovary Syndrome-like Traits in Female Rhesus Macaques. International Journal of Molecular Sciences. 23. PMID 35269778 DOI: 10.3390/ijms23052635  0.332
2019 Vyas AK, Veiga-Lopez A, Ye W, Abi Salloum B, Abbott DH, Yang S, Liao C, Kannan K, Padmanabhan V. Developmental programming: Sex-specific programming of growth upon prenatal bisphenol A exposure. Journal of Applied Toxicology : Jat. PMID 31338854 DOI: 10.1002/Jat.3836  0.33
2019 Kraynak M, Flowers M, Uhlrich D, Shapiro R, Kuehlmann A, Yohnk H, Abbott D, Levine J. SUN-469 Hypothalamic ERalpha Gene Silencing Diminishes Sexual Receptivity in Female Marmoset Monkeys Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-469  0.37
2019 Kraynak M, Goy R, Kapoor A, Levine J, Abbott D. MON-209 Systemic and Hypothalamic Hyperandrogenism Emerges Following Elimination of Ovarian and Extra-Ovarian Sources of Estradiol in Female Marmoset Monkeys Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-209  0.412
2018 Saltzman W, Abbott DH, Binkley N, Colman RJ. Maintenance of bone mass despite estrogen depletion in female common marmoset monkeys (Callithrix jacchus). American Journal of Primatology. e22905. PMID 30106167 DOI: 10.1002/Ajp.22905  0.551
2018 Abbott DH, Vepraskas SH, Horton TH, Terasawa E, Levine JE. Accelerated Episodic LH Release Accompanies Blunted Progesterone Regulation in PCOS-like Female Rhesus Monkeys (Macaca mulatta) Exposed to Testosterone During Early-to-Mid Gestation. Neuroendocrinology. PMID 29949806 DOI: 10.1159/000490570  0.326
2017 Kraynak M, Flowers MT, Shapiro RA, Kapoor A, Levine J, Abbott DH. Extra-Ovarian Gonadotropin Negative Feedback Revealed by Aromatase Inhibition in Female Marmoset Monkeys. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00058.2017. PMID 28679622 DOI: 10.1152/Ajpendo.00058.2017  0.376
2017 Abbott DH, Rayome BH, Dumesic DA, Lewis KC, Edwards AK, Wallen K, Wilson ME, Appt SE, Levine JE. Clustering of PCOS-like traits in naturally hyperandrogenic female rhesus monkeys. Human Reproduction (Oxford, England). 1-14. PMID 28333238 DOI: 10.1093/Humrep/Dex036  0.585
2017 Felder M, Kapur A, Simmons H, Abbott D, Patankar MS. Abstract TMEM-033: DEVELOPING A MONKEY MODEL FOR SPONTANEOUS TYPE I OVARIAN CANCER Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Tmem-033  0.318
2015 Mandel D, Kraynak M, Lewis K, Shah D, Bird I, Abbott D. 146: Discordant maternal effect on the DHEA/Cortisol ratio with mid versus late gestation initiation of 17OHPc in rhesus macaques American Journal of Obstetrics and Gynecology. 212: S89-S90. DOI: 10.1016/j.ajog.2014.10.192  0.306
2012 Aubert Y, Gustison ML, Gardner LA, Bohl MA, Lange JR, Allers KA, Sommer B, Datson NA, Abbott DH. Flibanserin and 8-OH-DPAT implicate serotonin in association between female marmoset monkey sexual behavior and changes in pair-bond quality. The Journal of Sexual Medicine. 9: 694-707. PMID 22304661 DOI: 10.1111/j.1743-6109.2011.02616.x  0.307
2011 Conley AJ, Plant TM, Abbott DH, Moeller BC, Stanley SD. Adrenal androgen concentrations increase during infancy in male rhesus macaques (Macaca mulatta). American Journal of Physiology. Endocrinology and Metabolism. 301: E1229-35. PMID 21900126 DOI: 10.1152/Ajpendo.00200.2011  0.383
2011 Saltzman W, Abbott DH. Hormonal and behavioral responses to stress in lactating and non-lactating female common marmosets (Callithrix jacchus). Physiology & Behavior. 104: 446-53. PMID 21600906 DOI: 10.1016/J.Physbeh.2011.05.005  0.624
2011 Saltzman W, Boettcher CA, Post JL, Abbott DH. Inhibition of maternal behaviour by central infusion of corticotrophin-releasing hormone in marmoset monkeys. Journal of Neuroendocrinology. 23: 1139-48. PMID 21554432 DOI: 10.1111/J.1365-2826.2011.02153.X  0.521
2011 Conley AJ, Moeller BC, Nguyen AD, Stanley SD, Plant TM, Abbott DH. Defining adrenarche in the rhesus macaque (Macaca mulatta), a non-human primate model for adrenal androgen secretion. Molecular and Cellular Endocrinology. 336: 110-6. PMID 21184803 DOI: 10.1016/J.Mce.2010.12.022  0.358
2010 Woller MJ, Tannenbaum PL, Schultz-Darken NJ, Eshelman BD, Abbott DH. Pulsatile gonadotropin-releasing hormone release from hypothalamic explants of male marmoset monkeys compared with male rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R70-8. PMID 19889867 DOI: 10.1152/ajpregu.00193.2009  0.635
2009 Dumesic DA, Patankar MS, Barnett DK, Lesnick TG, Hutcherson BA, Abbott DH. Early prenatal androgenization results in diminished ovarian reserve in adult female rhesus monkeys. Human Reproduction (Oxford, England). 24: 3188-95. PMID 19740899 DOI: 10.1093/humrep/dep324  0.348
2009 Pattison JC, Abbott DH, Saltzman W, Conley AJ, Bird IM. Plasticity of the zona reticularis in the adult marmoset adrenal cortex: voyages of discovery in the New World. The Journal of Endocrinology. 203: 313-26. PMID 19474057 DOI: 10.1677/Joe-08-0554  0.534
2009 Saltzman W, Abbott DH. Effects of elevated circulating cortisol concentrations on maternal behavior in common marmoset monkeys (Callithrix jacchus). Psychoneuroendocrinology. 34: 1222-34. PMID 19362777 DOI: 10.1016/J.Psyneuen.2009.03.012  0.543
2009 Saltzman W, Digby LJ, Abbott DH. Reproductive skew in female common marmosets: what can proximate mechanisms tell us about ultimate causes? Proceedings. Biological Sciences / the Royal Society. 276: 389-99. PMID 18945663 DOI: 10.1098/Rspb.2008.1374  0.635
2009 Abbott DH, Digby L, Saltzman W. Reproductive skew in female common marmosets: Contributionsof infanticide and subordinate self-restraint Reproductive Skew in Vertebrates: Proximate and Ultimate Causes. 337-368. DOI: 10.1017/CBO9780511641954.014  0.56
2008 Abbott DH, Zhou R, Bird IM, Dumesic DA, Conley AJ. Fetal programming of adrenal androgen excess: lessons from a nonhuman primate model of polycystic ovary syndrome. Endocrine Development. 13: 145-58. PMID 18493139 DOI: 10.1159/000134831  0.353
2008 Abbott DH, Barnett DK, Levine JE, Padmanabhan V, Dumesic DA, Jacoris S, Tarantal AF. Endocrine antecedents of polycystic ovary syndrome in fetal and infant prenatally androgenized female rhesus monkeys. Biology of Reproduction. 79: 154-63. PMID 18385445 DOI: 10.1095/Biolreprod.108.067702  0.308
2008 Saltzman W, Liedl KJ, Salper OJ, Pick RR, Abbott DH. Post-conception reproductive competition in cooperatively breeding common marmosets. Hormones and Behavior. 53: 274-86. PMID 18045596 DOI: 10.1016/J.Yhbeh.2007.10.005  0.594
2007 Tannenbaum PL, Schultz-Darken NJ, Woller MJ, Abbott DH. Gonadotrophin-releasing hormone (GnRH) release in marmosets II: pulsatile release of GnRH and pituitary gonadotrophin in adult females. Journal of Neuroendocrinology. 19: 354-63. PMID 17425610 DOI: 10.1111/j.1365-2826.2007.01535.x  0.6
2007 Tannenbaum PL, Schultz-Darken NJ, Saltzman W, Terasawa E, Woller MJ, Abbott DH. Gonadotrophin-releasing hormone (GnRH) release in marmosets I: in vivo measurement in ovary-intact and ovariectomised females. Journal of Neuroendocrinology. 19: 342-53. PMID 17425609 DOI: 10.1111/J.1365-2826.2007.01534.X  0.7
2007 Zhou R, Bruns CM, Bird IM, Kemnitz JW, Goodfriend TL, Dumesic DA, Abbott DH. Pioglitazone improves insulin action and normalizes menstrual cycles in a majority of prenatally androgenized female rhesus monkeys. Reproductive Toxicology (Elmsford, N.Y.). 23: 438-48. PMID 17306503 DOI: 10.1016/J.Reprotox.2006.12.009  0.337
2007 Pattison JC, Saltzman W, Abbott DH, Hogan BK, Nguyen AD, Husen B, Einspanier A, Conley AJ, Bird IM. Gender and gonadal status differences in zona reticularis expression in marmoset monkey adrenals: Cytochrome b5 localization with respect to cytochrome P450 17,20-lyase activity. Molecular and Cellular Endocrinology. 265: 93-101. PMID 17222503 DOI: 10.1016/J.Mce.2006.12.023  0.624
2006 Tardif S, Bales K, Williams L, Moeller EL, Abbott D, Schultz-Darken N, Mendoza S, Mason W, Bourgeois S, Ruiz J. Preparing New World monkeys for laboratory research. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 47: 307-15. PMID 16963811 DOI: 10.1093/Ilar.47.4.307  0.647
2006 Saltzman W, Hogan BK, Horman BM, Abbott DH. Social suppression of cortisol in female marmosets: role of luteinizing hormone/chorionic gonadotropin. General and Comparative Endocrinology. 149: 90-9. PMID 16806216 DOI: 10.1016/J.Ygcen.2006.05.007  0.634
2006 Alencar AI, Sousa MB, Abbott DH, Yamamoto ME. Contested dominance modifies the anovulatory consequences of social subordination in female marmosets. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 39: 647-58. PMID 16648903 DOI: 10.1590/S0100-879X2006000500012  0.395
2006 Saltzman W, Hogan BK, Allen AJ, Horman BM, Abbott DH. Hypoestrogenism does not mediate social suppression of cortisol in subordinate female marmosets. Psychoneuroendocrinology. 31: 692-702. PMID 16624494 DOI: 10.1016/J.Psyneuen.2006.01.006  0.651
2006 Abbott DH, Padmanabhan V, Dumesic DA. Contributions of androgen and estrogen to fetal programming of ovarian dysfunction. Reproductive Biology and Endocrinology : Rb&E. 4: 17. PMID 16606451 DOI: 10.1186/1477-7827-4-17  0.309
2006 Saltzman W, Hogan BK, Abbott DH. Diminished cortisol levels in subordinate female marmosets are associated with altered central drive to the hypothalamic-pituitary-adrenal axis. Biological Psychiatry. 60: 843-9. PMID 16499881 DOI: 10.1016/J.Biopsych.2005.12.006  0.604
2006 Barnett DK, Bunnell TM, Millar RP, Abbott DH. Gonadotropin-releasing hormone II stimulates female sexual behavior in marmoset monkeys. Endocrinology. 147: 615-23. PMID 16179411 DOI: 10.1210/en.2005-0662  0.305
2005 Zhou R, Bird IM, Dumesic DA, Abbott DH. Adrenal hyperandrogenism is induced by fetal androgen excess in a rhesus monkey model of polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism. 90: 6630-7. PMID 16174719 DOI: 10.1210/jc.2005-0691  0.329
2005 Dumesic DA, Schramm RD, Abbott DH. Early origins of polycystic ovary syndrome. Reproduction, Fertility, and Development. 17: 349-60. PMID 15745643 DOI: 10.1071/RD04092  0.378
2005 Saltzman W, Abbott DH. Diminished maternal responsiveness during pregnancy in multiparous female common marmosets. Hormones and Behavior. 47: 151-63. PMID 15664018 DOI: 10.1016/J.Yhbeh.2004.10.001  0.569
2005 Pattison JC, Abbott DH, Saltzman W, Nguyen AD, Henderson G, Jing H, Pryce CR, Allen AJ, Conley AJ, Bird IM. Male marmoset monkeys express an adrenal fetal zone at birth, but not a zona reticularis in adulthood. Endocrinology. 146: 365-74. PMID 15459122 DOI: 10.1210/En.2004-0689  0.573
2004 Bruns CM, Baum ST, Colman RJ, Eisner JR, Kemnitz JW, Weindruch R, Abbott DH. Insulin resistance and impaired insulin secretion in prenatally androgenized male rhesus monkeys. The Journal of Clinical Endocrinology and Metabolism. 89: 6218-23. PMID 15579780 DOI: 10.1210/Jc.2004-0918  0.323
2004 Schultz-Darken NJ, Pape RM, Tannenbaum PL, Saltzman W, Abbott DH. Novel restraint system for neuroendocrine studies of socially living common marmoset monkeys. Laboratory Animals. 38: 393-405. PMID 15479554 DOI: 10.1258/0023677041958918  0.686
2004 Pazol K, Kaplan JR, Abbott D, Appt SE, Wilson ME. Practical measurement of total and bioavailable estradiol in female macaques. Clinica Chimica Acta; International Journal of Clinical Chemistry. 340: 117-26. PMID 14734203 DOI: 10.1016/J.Cccn.2003.10.010  0.304
2004 Saltzman W, Prudom SL, Schultz-Darken NJ, Wittwer DJ, Abbott DH. Social suppression of cortisol in female marmoset monkeys: role of circulating ACTH levels and glucocorticoid negative feedback. Psychoneuroendocrinology. 29: 141-61. PMID 14604597 DOI: 10.1016/S0306-4530(02)00159-2  0.644
2004 Saltzman W, Pick RR, Salper OJ, Liedl KJ, Abbott DH. Onset of plural cooperative breeding in common marmoset families following replacement of the breeding male Animal Behaviour. 68: 59-73. DOI: 10.1016/J.Anbehav.2003.07.020  0.592
2003 Dumesic DA, Schramm RD, Bird IM, Peterson E, Paprocki AM, Zhou R, Abbott DH. Reduced intrafollicular androstenedione and estradiol levels in early-treated prenatally androgenized female rhesus monkeys receiving follicle-stimulating hormone therapy for in vitro fertilization. Biology of Reproduction. 69: 1213-9. PMID 12801996 DOI: 10.1095/biolreprod.102.015164  0.353
2003 Abbott DH, Keverne EB, Bercovitch FB, Shively CA, Mendoza SP, Saltzman W, Snowdon CT, Ziegler TE, Banjevic M, Garland T, Sapolsky RM. Are subordinates always stressed? A comparative analysis of rank differences in cortisol levels among primates. Hormones and Behavior. 43: 67-82. PMID 12614636 DOI: 10.1016/S0018-506X(02)00037-5  0.695
2003 Eisner JR, Dumesic DA, Kemnitz JW, Colman RJ, Abbott DH. Increased adiposity in female rhesus monkeys exposed to androgen excess during early gestation. Obesity Research. 11: 279-86. PMID 12582225 DOI: 10.1038/Oby.2003.42  0.417
2002 Riley RC, Tannenbaum PL, Abbott DH, Atkinson JP. Cutting edge: inhibiting measles virus infection but promoting reproduction: an explanation for splicing and tissue-specific expression of CD46. Journal of Immunology (Baltimore, Md. : 1950). 169: 5405-9. PMID 12421914  0.551
2002 Dumesic DA, Schramm RD, Peterson E, Paprocki AM, Zhou R, Abbott DH. Impaired developmental competence of oocytes in adult prenatally androgenized female rhesus monkeys undergoing gonadotropin stimulation for in vitro fertilization. The Journal of Clinical Endocrinology and Metabolism. 87: 1111-9. PMID 11889174 DOI: 10.1210/jcem.87.3.8287  0.345
2002 Eisner JR, Barnett MA, Dumesic DA, Abbott DH. Ovarian hyperandrogenism in adult female rhesus monkeys exposed to prenatal androgen excess. Fertility and Sterility. 77: 167-72. PMID 11779609 DOI: 10.1016/S0015-0282(01)02947-8  0.391
2000 Saltzman W, Prudom SL, Schultz-Darken NJ, Abbott DH. Reduced adrenocortical responsiveness to adrenocorticotropic hormone (ACTH) in socially subordinate female marmoset monkeys. Psychoneuroendocrinology. 25: 463-77. PMID 10818281 DOI: 10.1016/S0306-4530(00)00003-2  0.649
1999 Baker JV, Abbott DH, Saltzman W. Social determinants of reproductive failure in male common marmosets housed with their natal family. Animal Behaviour. 58: 501-513. PMID 10479365 DOI: 10.1006/Anbe.1999.1200  0.628
1998 Smith TE, Abbott DH. Behavioral discrimination between circumgenital odor from peri-ovulatory dominant and anovulatory female common marmosets (Callithrix jacchus). American Journal of Primatology. 46: 265-84. PMID 9839902 DOI: 10.1002/(SICI)1098-2345(1998)46:4<265::AID-AJP1>3.0.CO;2-D  0.379
1998 Abbott DH, Saltzman W, Schultz-Darken NJ, Tannenbaum PL. Adaptations to subordinate status in female marmoset monkeys. Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 119: 261-74. PMID 9826999 DOI: 10.1016/S0742-8413(98)00015-2  0.745
1998 Saltzman W, Schultz-Darken NJ, Wegner FH, Wittwer DJ, Abbott DH. Suppression of cortisol levels in subordinate female marmosets: Reproductive and social contributions Hormones and Behavior. 33: 58-74. PMID 9571014 DOI: 10.1006/Hbeh.1998.1436  0.65
1997 Faulkes CG, Abbott DH, O'Brien HP, Lau L, Roy MR, Wayne RK, Bruford MW. Micro- and macrogeographical genetic structure of colonies of naked mole-rats Heterocephalus glaber. Molecular Ecology. 6: 615-28. PMID 9226945 DOI: 10.1046/J.1365-294X.1997.00227.X  0.531
1997 Smith TE, Faulkes CG, Abbott DH. Combined olfactory contact with the parent colony and direct contact with nonbreeding animals does not maintain suppression of ovulation in female naked mole-rats (Heterocephalus glaber). Hormones and Behavior. 31: 277-88. PMID 9213141 DOI: 10.1006/Hbeh.1997.1384  0.641
1997 Saltzman W, Schultz-Darken NJ, Severin JM, Abbott DH. Escape from social suppression of sexual behavior and of ovulation in female common marmosets. Annals of the New York Academy of Sciences. 807: 567-70. PMID 9071400 DOI: 10.1111/J.1749-6632.1997.Tb51970.X  0.643
1997 Abbott DH, Saltzman W, Schultz-Darken NJ, Smith TE. Specific neuroendocrine mechanisms not involving generalized stress mediate social regulation of female reproduction in cooperatively breeding marmoset monkeys. Annals of the New York Academy of Sciences. 807: 219-38. PMID 9071354 DOI: 10.1111/J.1749-6632.1997.Tb51923.X  0.596
1997 Saltzman W, Severin JM, Schultz-Darken NJ, Abbott DH. Behavioral and social correlates of escape from suppression of ovulation in female common marmosets housed with the natal family. American Journal of Primatology. 41: 1-21. PMID 9064194 DOI: 10.1002/(Sici)1098-2345(1997)41:1<1::Aid-Ajp1>3.0.Co;2-0  0.58
1997 Saltzman W, Schultz-Darken NJ, Abbott DH. Familial influences on ovulatory function in common marmosets (Callithrix jacchus) American Journal of Primatology. 41: 159-177. PMID 9057963 DOI: 10.1002/(Sici)1098-2345(1997)41:3<159::Aid-Ajp1>3.0.Co;2-W  0.58
1997 Dumesic DA, Abbott DH, Eisner JR, Goy RW. Prenatal exposure of female rhesus monkeys to testosterone propionate increases serum luteinizing hormone levels in adulthood. Fertility and Sterility. 67: 155-63. PMID 8986701 DOI: 10.1016/S0015-0282(97)81873-0  0.662
1997 Smith TE, Abbott DH, Tomlinson AJ, Mlotkiewicz JA. Differential Display of Investigative Behavior Permits Discrimination of Scent Signatures from Familiar and Unfamiliar Socially Dominant Female Marmoset Monkeys (Callithrix jacchus) Journal of Chemical Ecology. 23: 2523-2546. DOI: 10.1023/B:JOEC.0000006664.38169.e5  0.339
1996 Saltzman W, Schultz-Darken NJ, Abbott DH. Behavioural and endocrine predictors of dominance and tolerance in female common marmosets, Callithrix jacchus Animal Behaviour. 51: 657-674. DOI: 10.1006/Anbe.1996.0070  0.643
1995 Margulis SW, Saltzman W, Abbott DH. Behavioral and hormonal changes in female naked mole-rats (Heterocephalus glaber) following removal of the breeding female from a colony Hormones and Behavior. 29: 227-247. PMID 7557925 DOI: 10.1006/Hbeh.1995.1017  0.629
1994 Saltzman W, Schultz-Darken NJ, Scheffler G, Wegner FH, Abbott DH. Social and reproductive influences on plasma cortisol in female marmoset monkeys Physiology and Behavior. 56: 801-810. PMID 7800752 DOI: 10.1016/0031-9384(94)90246-1  0.652
1991 Faulkes C, Abbott D, Smith T. Socially induced suppression of reproduction in colonies of naked mole-rats Applied Animal Behaviour Science. 31: 293-294. DOI: 10.1016/0168-1591(91)90022-P  0.597
1991 Abbott D, George L, Barrett J, Cheeseman D. Social dominance and the induction of infertility in subordinate female marmoset monkeys Applied Animal Behaviour Science. 31: 293. DOI: 10.1016/0168-1591(91)90021-O  0.38
1990 Faulkes CG, Abbott DH, Mellor AL. Investigation of genetic diversity in wild colonies of naked mole-rats (Heterocephalus glaber) by DNA fingerprinting Journal of Zoology. 221: 87-97. DOI: 10.1111/J.1469-7998.1990.Tb03778.X  0.542
1989 Abbott DH, Barrett J, Faulkes CG, George LM. Social contraception in naked mole-rats and marmoset monkeys Journal of Zoology. 219: 703-710. DOI: 10.1111/J.1469-7998.1989.Tb02616.X  0.627
1984 Abbott DH. Behavioral and physiological suppression of fertility in subordinate marmoset monkeys. American Journal of Primatology. 6: 169-186. PMID 31986838 DOI: 10.1002/ajp.1350060305  0.423
1984 French JA, Abbott DH, Snowdon CT. The effect of social environment on estrogen excretion, scent marking, and sociosexual behavior in tamarins (Saguinus oedipus). American Journal of Primatology. 6: 155-167. PMID 31986830 DOI: 10.1002/Ajp.1350060304  0.411
1984 Abbott DH, Holman SD, Berman M, Neff DA, Goy RW. Effects of opiate antagonists on hormones and behavior of male and female rhesus monkeys. Archives of Sexual Behavior. 13: 1-25. PMID 6424632 DOI: 10.1007/BF01542974  0.656
1983 French JA, Abbott DH, Scheffler G, Robinson JA, Goy RW. Cyclic excretion of urinary oestrogens in female tamarins (Saguinus oedipus). Journal of Reproduction and Fertility. 68: 177-84. PMID 6405030 DOI: 10.1530/Jrf.0.0680177  0.634
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