Jason M. Dwyer - Publications

Affiliations: 
Yale University, New Haven, CT 

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Deyama S, Bang E, Wohleb ES, Li XY, Kato T, Gerhard DM, Dutheil S, Dwyer JM, Taylor SR, Picciotto MR, Duman RS. Role of Neuronal VEGF Signaling in the Prefrontal Cortex in the Rapid Antidepressant Effects of Ketamine. The American Journal of Psychiatry. appiajp201817121368. PMID 30606046 DOI: 10.1176/appi.ajp.2018.17121368  1
2016 Lepack AE, Bang E, Lee B, Dwyer JM, Duman RS. Fast-acting antidepressants rapidly stimulate ERK signaling and BDNF release in primary neuronal cultures. Neuropharmacology. PMID 27634096 DOI: 10.1016/j.neuropharm.2016.09.011  1
2015 Navarria A, Wohleb ES, Voleti B, Ota KT, Dutheil S, Lepack AE, Dwyer JM, Fuchikami M, Becker A, Drago F, Duman RS. Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors. Neurobiology of Disease. 82: 254-261. PMID 26102021 DOI: 10.1016/j.nbd.2015.06.012  1
2015 Dwyer JM, Maldonado-Avilés JG, Lepack AE, DiLeone RJ, Duman RS. Ribosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 112: 6188-93. PMID 25918363 DOI: 10.1073/pnas.1505289112  1
2015 Lepack AE, Fuchikami M, Dwyer JM, Banasr M, Duman RS. BDNF release is required for the behavioral actions of ketamine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25539510 DOI: 10.1093/ijnp/pyu033  1
2015 Navarria A, Wohleb ES, Voleti B, Ota KT, Dutheil S, Lepack AE, Dwyer JM, Fuchikami M, Becker A, Drago F, Duman RS. Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors Neurobiology of Disease. 82: 254-261. DOI: 10.1016/j.nbd.2015.06.012  1
2013 Dwyer JM, Lepack AE, Duman RS. mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure. Journal of Molecular Psychiatry. 1: 15. PMID 25408908 DOI: 10.1186/2049-9256-1-15  1
2013 Liu RJ, Fuchikami M, Dwyer JM, Lepack AE, Duman RS, Aghajanian GK. GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2268-77. PMID 23680942 DOI: 10.1038/npp.2013.128  1
2013 Dwyer JM, Duman RS. Activation of mammalian target of rapamycin and synaptogenesis: role in the actions of rapid-acting antidepressants. Biological Psychiatry. 73: 1189-98. PMID 23295207 DOI: 10.1016/j.biopsych.2012.11.011  1
2013 Hughes ZA, Neal SJ, Smith DL, Sukoff Rizzo SJ, Pulicicchio CM, Lotarski S, Lu S, Dwyer JM, Brennan J, Olsen M, Bender CN, Kouranova E, Andree TH, Harrison JE, Whiteside GT, et al. Negative allosteric modulation of metabotropic glutamate receptor 5 results in broad spectrum activity relevant to treatment resistant depression. Neuropharmacology. 66: 202-14. PMID 22551786 DOI: 10.1016/j.neuropharm.2012.04.007  1
2012 Dwyer JM, Lepack AE, Duman RS. mTOR activation is required for the antidepressant effects of mGluR₂/₃ blockade. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 429-34. PMID 22114864 DOI: 10.1017/S1461145711001702  1
2011 Banasr M, Dwyer JM, Duman RS. Cell atrophy and loss in depression: reversal by antidepressant treatment. Current Opinion in Cell Biology. 23: 730-7. PMID 21996102 DOI: 10.1016/j.ceb.2011.09.002  1
2011 Sukoff Rizzo SJ, Leonard SK, Gilbert A, Dollings P, Smith DL, Zhang MY, Di L, Platt BJ, Neal S, Dwyer JM, Bender CN, Zhang J, Lock T, Kowal D, Kramer A, et al. The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise? The Journal of Pharmacology and Experimental Therapeutics. 338: 345-52. PMID 21508084 DOI: 10.1124/jpet.110.177378  1
2011 Li N, Liu RJ, Dwyer JM, Banasr M, Lee B, Son H, Li XY, Aghajanian G, Duman RS. Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biological Psychiatry. 69: 754-61. PMID 21292242 DOI: 10.1016/j.biopsych.2010.12.015  1
2011 Gilbert AM, Bursavich MG, Lombardi S, Adedoyin A, Dwyer JM, Hughes Z, Kern JC, Khawaja X, Rosenzweig-Lipson S, Moore WJ, Neal SJ, Olsen M, Rizzo SJ, Springer D. 3-(Pyridin-2-yl-ethynyl)benzamide metabotropic glutamate receptor 5 negative allosteric modulators: hit to lead studies. Bioorganic & Medicinal Chemistry Letters. 21: 195-9. PMID 21126874 DOI: 10.1016/j.bmcl.2010.11.038  1
2010 Li N, Lee B, Liu RJ, Banasr M, Dwyer JM, Iwata M, Li XY, Aghajanian G, Duman RS. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science (New York, N.Y.). 329: 959-64. PMID 20724638 DOI: 10.1126/science.1190287  1
2010 Whiteside GT, Dwyer JM, Harrison JE, Beyer CE, Cummons T, Manzino L, Mark L, Johnston GH, Strassle BW, Adedoyin A, Lu P, Piesla MJ, Pulicicchio CM, Erve JC, Platt BJ, et al. WAY-318068: a novel, potent and selective noradrenaline re-uptake inhibitor with activity in rodent models of pain and depression. British Journal of Pharmacology. 160: 1105-18. PMID 20590604 DOI: 10.1111/j.1476-5381.2010.00690.x  1
2010 Kelly MP, Logue SF, Brennan J, Day JP, Lakkaraju S, Jiang L, Zhong X, Tam M, Sukoff Rizzo SJ, Platt BJ, Dwyer JM, Neal S, Pulito VL, Agostino MJ, Grauer SM, et al. Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 107: 8457-62. PMID 20404172 DOI: 10.1073/pnas.1000730107  1
2010 Beyer CE, Dwyer JM, Piesla MJ, Platt BJ, Shen R, Rahman Z, Chan K, Manners MT, Samad TA, Kennedy JD, Bingham B, Whiteside GT. Depression-like phenotype following chronic CB1 receptor antagonism. Neurobiology of Disease. 39: 148-55. PMID 20381618 DOI: 10.1016/j.nbd.2010.03.020  1
2010 Beyer CE, Dwyer JM, Platt BJ, Neal S, Luo B, Ling HP, Lin Q, Mark RJ, Rosenzweig-Lipson S, Schechter LE. Angiotensin IV elevates oxytocin levels in the rat amygdala and produces anxiolytic-like activity through subsequent oxytocin receptor activation. Psychopharmacology. 209: 303-11. PMID 20224888 DOI: 10.1007/s00213-010-1791-1  1
2010 Dwyer JM, Platt BJ, Rizzo SJ, Pulicicchio CM, Wantuch C, Zhang MY, Cummons T, Leventhal L, Bender CN, Zhang J, Kowal D, Lu S, Rajarao SJ, Smith DL, Shilling AD, et al. Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 1193-205. PMID 20047711 DOI: 10.1017/S1461145709991088  1
2010 Ring RH, Schechter LE, Leonard SK, Dwyer JM, Platt BJ, Graf R, Grauer S, Pulicicchio C, Resnick L, Rahman Z, Sukoff Rizzo SJ, Luo B, Beyer CE, Logue SF, Marquis KL, et al. Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist. Neuropharmacology. 58: 69-77. PMID 19615387 DOI: 10.1016/j.neuropharm.2009.07.016  1
2009 Kelly MP, Logue SF, Dwyer JM, Beyer CE, Majchrowski H, Cai Z, Liu Z, Adedoyin A, Rosenzweig-Lipson S, Comery TA. The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers. Pharmacology, Biochemistry, and Behavior. 92: 649-54. PMID 19303035 DOI: 10.1016/j.pbb.2009.03.003  1
2009 Balu DT, Hodes GE, Hill TE, Ho N, Rahman Z, Bender CN, Ring RH, Dwyer JM, Rosenzweig-Lipson S, Hughes ZA, Schechter LE, Lucki I. Flow cytometric analysis of BrdU incorporation as a high-throughput method for measuring adult neurogenesis in the mouse. Journal of Pharmacological and Toxicological Methods. 59: 100-7. PMID 19121403 DOI: 10.1016/j.vascn.2008.12.002  1
2009 Dwyer JM, Rizzo SJ, Neal SJ, Lin Q, Jow F, Arias RL, Rosenzweig-Lipson S, Dunlop J, Beyer CE. Acid sensing ion channel (ASIC) inhibitors exhibit anxiolytic-like activity in preclinical pharmacological models. Psychopharmacology. 203: 41-52. PMID 18949460 DOI: 10.1007/s00213-008-1373-7  1
2008 Arias RL, Sung ML, Vasylyev D, Zhang MY, Albinson K, Kubek K, Kagan N, Beyer C, Lin Q, Dwyer JM, Zaleska MM, Bowlby MR, Dunlop J, Monaghan M. Amiloride is neuroprotective in an MPTP model of Parkinson's disease. Neurobiology of Disease. 31: 334-41. PMID 18606547 DOI: 10.1016/j.nbd.2008.05.008  1
2008 Hughes ZA, Liu F, Platt BJ, Dwyer JM, Pulicicchio CM, Zhang G, Schechter LE, Rosenzweig-Lipson S, Day M. WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology. 54: 1136-42. PMID 18423777 DOI: 10.1016/j.neuropharm.2008.03.004  1
2008 Leonard SK, Dwyer JM, Sukoff Rizzo SJ, Platt B, Logue SF, Neal SJ, Malberg JE, Beyer CE, Schechter LE, Rosenzweig-Lipson S, Ring RH. Pharmacology of neuropeptide S in mice: therapeutic relevance to anxiety disorders. Psychopharmacology. 197: 601-11. PMID 18311561 DOI: 10.1007/s00213-008-1080-4  1
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